diff --git "a/OPI_DATA/AP/Function/test/UniProtSeq_function_test.jsonl" "b/OPI_DATA/AP/Function/test/UniProtSeq_function_test.jsonl"
new file mode 100644--- /dev/null
+++ "b/OPI_DATA/AP/Function/test/UniProtSeq_function_test.jsonl"
@@ -0,0 +1,4562 @@
+{"id": "function_test_0", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MWLKLFFLLLYFLVLFVLARFFEAIVWYETGIFATQLVDPVALSFKKLKTILECRGLGYSGLPEKKDVRELVEKSGDLMEGELYSALKEEEASESVSSTNFSGEMHFYELVEDTKDGIWLVQVIANDRSPLVGKIHWEKMVKKVSRFGIRTGTFNCSSDPRYCRRRGWVRSTLIMSVPQTSTSKGKVMLKEYSGRKIEVEHIFKWITAHAASRIKTIYNAEHLKEEWNKSDQYWLKIYLFANLDQPPAFFSALSIKFTGRVEFIFVNVENWDNKSYMTDIGIYNMPSYILRTPEGIYRYGNHTGEFISLQAMDSFLRSLQPEVNDLFVLSLVLVNLMAWMDLFITQGATIKRFVVLISTLGTYNSLLIISWLPVLGFLQLPYLDSFYEYSLKLLRYSNTTTLASWVRADWMFYSSHPALFLSTYLGHGLLIDYFEKKRRRNNNNDEVNANNLEWLSSLWDWYTSYLFHPIASFQNFPVESDWDEDPDLFLERLAFPDLWLHPLIPTDYIKNLPMWRFKCLGVQSEEEMSEGSQDTENDSESENTDTLSSEKEVFEDKQSVLHNSPGTASHCDAEACSCANKYCQTSPCERKGRSYGSYNTNEDMEPDWLTWPADMLHCTECVVCLENFENGCLLMGLPCGHVFHQNCIVMWLAGGRHCCPVCRWPSYKKKQPYAQHQPLSNDVPS", "output": "Acts as an E2-dependent E3 ubiquitin-protein ligase, probably involved in the ER-associated protein degradation pathway."}]}
+{"id": "function_test_1", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MASCSFTRDQATRRLRGAAAAAAAALAAVVTTPLLSSGTPTALIGTGSSCPGAMWLSTATGSRSDSESEEEDLPVGEEVCKRGYLRKQKHGHRRYFVLKLETADAPARLEYYENARKFRHSVRAAAAAAAAAASGAAIPPLIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMVAENESEQESWYLLLSRLILESKRRRCGTLGAQPDGEPAALAAAAAAEPPFYKDVWQVIVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYSISIGAHLLTLLSARRHLGLVPLEPGGWLRRSRFEQFCHLRAIGDGEDEMLFTRRFVTPSEPVAHSRRGRLHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKECKEAKEVKDAEIPEGAARGPHRARAFDEDEDDPYVPMRPGVATPLVSSSDYMPMAPQNVSASKKRHSRSPFEDSRGYMMMFPRVSPPPAPSPPKAPDTNKEDDSKDNDSESDYMFMAPGAGAIPKNPRNPQGGSSSKSWSSYFSLPNPFRSSPLGQNDNSEYVPMLPGKFLGRGLDKEVSYNWDPKDAASKPSGEGSFSKPGDGGSPSKPSDHEPPKNKAKRPNRLSFITKGYKIKPKPQKPTHEQREADSSSDYVNMDFTKRESNTPAPSTQGLPDSWGIIAEPRQSAFSNYVNVEFGVPFPNPANDLSDLLRAIPRANPLSLDSARWPLPPLPLSATGSNAIEEEGDYIEVIFNSAMTPAMALADSAIRYDAETGRIYVVDPFSECCMDISLSPSRCSEPPPVARLLQEEEQERRRPQSRSQSFFAAARAAVSAFPTDSLERDLSPSSAPAVASAAEPTLALSQVVAAASALAAAPGIGAAAAAAGFDSASARWFQPVANAADAEAVRGAQDVAGGSNPGAHNPSANLARGDNQAGGAAAAAAAPEPPPRSRRVPRPPEREDSDNDDDTHVRMDFARRDNQFDSPKRGR", "output": "Acts as an interface between multiple growth factor receptors possessing tyrosine kinase activity, such as insulin receptor, IGF1R and FGFR1, and a complex network of intracellular signaling molecules containing SH2 domains. Involved in the IGF1R mitogenic signaling pathway. Promotes the AKT1 signaling pathway and BAD phosphorylation during insulin stimulation without activation of RPS6KB1 or the inhibition of apoptosis. Interaction with GRB2 enhances insulin-stimulated mitogen-activated protein kinase activity. May be involved in nonreceptor tyrosine kinase signaling in myoblasts. Plays a pivotal role in the proliferation/differentiation of hepatoblastoma cell through EPHB2 activation upon IGF1 stimulation. May play a role in the signal transduction in response to insulin and to a lesser extent in response to IL4 and GH on mitogenesis. Plays a role in growth, reproduction and glucose homeostasis. May act as negative regulators of the IGF1 signaling pathway by suppressing the function of IRS1 and IRS2."}]}
+{"id": "function_test_2", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSPVLHFYVRPSGHEGAAPGHTRRKLQGKLPELQGVETELCYNVNWTAEALPSAEETKKLMWLFGCPLLLDDVARESWLLPGSNDLLLEVGPRLNFSTPTSTNIVSVCRATGLGPVDRVETTRRYRLSFAHPPSAEVEAIALATLHDRMTEQHFPHPIQSFSPESMPEPLNGPINILGEGRLALEKANQELGLALDSWDLDFYTKRFQELQRNPSTVEAFDLAQSNSEHSRHWFFKGQLHVDGQKLVHSLFESIMSTQESSNPNNVLKFCDNSSAIQGKEVRFLRPEDPTRPSRFQQQQGLRHVVFTAETHNFPTGVCPFSGATTGTGGRIRDVQCTGRGAHVVAGTAGYCFGNLHIPGYNLPWEDPSFQYPGNFARPLEVAIEASNGASDYGNKFGEPVLAGFARSLGLQLPDGQRREWIKPIMFSGGIGSMEADHISKEAPEPGMEVVKVGGPVYRIGVGGGAASSVQVQGDNTSDLDFGAVQRGDPEMEQKMNRVIRACVEAPKGNPICSLHDQGAGGNGNVLKELSDPAGAIIYTSRFQLGDPTLNALEIWGAEYQESNALLLRSPNRDFLTHVSARERCPACFVGTITGDRRIVLVDDRECPVRRNGQGDAPPTPLPTPVDLELEWVLGKMPRKEFFLQRKPPMLQPLALPPGLSVHQALERVLRLPAVASKRYLTNKVDRSVGGLVAQQQCVGPLQTPLADVAVVALSHEELIGAATALGEQPVKSLLDPKVAARLAVAEALTNLVFALVTDLRDVKCSGNWMWAAKLPGEGAALADACEAMVAVMAALGVAVDGGKDSLSMAARVGTETVRAPGSLVISAYAVCPDITATVTPDLKHPEGRGHLLYVALSPGQHRLGGTALAQCFSQLGEHPPDLDLPENLVRAFSITQGLLKDRLLCSGHDVSDGGLVTCLLEMAFAGNCGLQVDVPVPRVDVLSVLFAEEPGLVLEVQEPDLAQVLKRYRDAGLHCLELGHTGEAGPHAMVRVSVNGAVVLEEPVGELRALWEETSFQLDRLQAEPRCVAEEERGLRERMGPSYCLPPTFPKASVPREPGGPSPRVAILREEGSNGDREMADAFHLAGFEVWDVTMQDLCSGAIGLDTFRGVAFVGGFSYADVLGSAKGWAAAVTFHPRAGAELRRFRKRPDTFSLGVCNGCQLLALLGWVGGDPNEDAAEMGPDSQPARPGLLLRHNLSGRYESRWASVRVGPGPALMLRGMEGAVLPVWSAHGEGYVAFSSPELQAQIEARGLAPLHWADDDGNPTEQYPLNPNGSPGGVAGICSCDGRHLAVMPHPERAVRPWQWAWRPPPFDTLTTSPWLQLFINARNWTLEGSC", "output": "Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate."}]}
+{"id": "function_test_3", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKSLSLLLAVALGLATAVSAGPAVIECWFVEDASGKGLAKRPGALLLRQGPGEPPPRPDLDPELYLSVHDPAGALQAAFRRYPRGAPAPHCEMSRFVPLPASAKWASGLTPAQNCPRALDGAWLMVSISSPVLSLSSLLRPQPEPQQEPVLITMATVVLTVLTHTPAPRVRLGQDALLDLSFAYMPPTSEAASSLAPGPPPFGLEWRRQHLGKGHLLLAATPGLNGQMPAAQEGAVAFAAWDDDEPWGPWTGNGTFWLPTVQPFQEGTYLATIHLPYLQGQVTLELAVYKPPKVSLMPATLARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSALRHHSDGSVSLSGHLQPPPVTTEQHGARYACRIHHPSLPASGRSAEVTLEVAGLSGPSLEDSVGLFLSAFLLLGLFKALGWAAVYLSTCKDSKKKAE", "output": "Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading)."}]}
+{"id": "function_test_4", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVEAFCATWKLTNSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDKVVIRTLSTFKNTEISFQLGEEFDETTADDRNCKSVVSLDGDKLVHIQKWDGKETNFVREIKDGKMVMTLTFGDVVAVRHYEKA", "output": "B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers (By similarity)."}]}
+{"id": "function_test_5", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSSHHTTFPFDPERRVRSTLKKVFGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPALLAKGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQERKELLADLEREKPQTKILYITPEMAASSSFQPTLNSLVSRHLLSYLVVDEAHCVSQWGHDFRPDYLRLGALRSRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYDVQFKELISDPYGNLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRNDRDQVSFLIRKEVAKLQEKRGNKASDKATIMAFDALVTFCEELGCRHAAIAKYFGDALPACAKGCDHCQNPTAVRRRLEALERSSSWSKTCIGPSQGNGFDPELYEGGRKGYGDFSRYDEGSGGSGDEGRDEAHKREWNLFYQKQMQLRKGKDPKIEEFVPPDENCPLKEASSRRIPRLTVKAREHCLRLLEEALSSNRQSTRTADEADLRAKAVELEHETFRNAKVANLYKASVLKKVADIHRASKDGQPYDMGGSAKSCSAQAEPPEPNEYDIPPASHVYSLKPKRVGAGFPKGSCPFQTATELMETTRIREQAPQPERGGEHEPPSRPCGLLDEDGSEPLPGPRGEVPGGSAHYGGPSPEKKAKSSSGGSSLAKGRASKKQQLLATAAHKDSQSIARFFCRRVESPALLASAPEAEGACPSCEGVQGPPMAPEKYTGEEDGAGGHSPAPPQTEECLRERPSTCPPRDQGTPEVQPTPAKDTWKGKRPRSQQENPESQPQKRPRPSAKPSVVAEVKGSVSASEQGTLNPTAQDPFQLSAPGVSLKEAANVVVKCLTPFYKEGKFASKELFKGFARHLSHLLTQKTSPGRSVKEEAQNLIRHFFHGRARCESEADWHGLCGPQR", "output": "DNA helicase that plays an important role in DNA replication, transcription and repair . Binds to the RNA polymerase II subunit POLR2A during transcription elongation and suppresses transcription-associated genomic instability . Associates also with POLR1A and enforces the stability of ribosomal DNA arrays . Plays an important role in mitotic chromosome separation after cross-over events and cell cycle progress . Mechanistically, removes RAD51 filaments protecting stalled replication forks at common fragile sites and stimulates MUS81-EME1 endonuclease leading to mitotic DNA synthesis . Required for efficient DNA repair, including repair of inter-strand cross-links . Stimulates DNA decatenation mediated by TOP2A. Prevents sister chromatid exchange and homologous recombination."}]}
+{"id": "function_test_6", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLRRPAPALAPAARLLLAGLLCGGGVWAARVNKHKPWLEPTYHGIVTENDNTVLLDPPLIALDKDAPLRFAESFEVTVTKEGEICGFKIHGQNVPFDAVVVDKSTGEGVIRSKEKLDCELQKDYSFTIQAYDCGKGPDGTNVKKSHKATVHIQVNDVNEYAPVFKEKSYKATVIEGKQYDSILRVEAVDADCSPQFSQICSYEIITPDVPFTVDKDGYIKNTEKLNYGKEHQYKLTVTAYDCGKKRATEDVLVKISIKPTCTPGWQGWNNRIEYEPGTGALAVFPNIHLETCDEPVASVQATVELETSHIGKGCDRDTYSEKSLHRLCGAAAGTAELLPSPSGSLNWTMGLPTDNGHDSDQVFEFNGTQAVRIPDGVVSVSPKEPFTISVWMRHGPFGRKKETILCSSDKTDMNRHHYSLYVHGCRLIFLFRQDPSEEKKYRPAEFHWKLNQVCDEEWHHYVLNVEFPSVTLYVDGTSHEPFSVTEDYPLHPSKIETQLVVGACWQEFSGVENDNETEPVTVASAGGDLHMTQFFRGNLAGLTLRSGKLADKKVIDCLYTCKEGLDLQVLEDSGRGVQIQAHPSQLVLTLEGEDLGELDKAMQHISYLNSRQFPTPGIRRLKITSTIKCFNEATCISVPPVDGYVMVLQPEEPKISLSGVHHFARAASEFESSEGVFLFPELRIISTITREVEPEGDGAEDPTVQESLVSEEIVHDLDTCEVTVEGEELNHEQESLEVDMARLQQKGIEVSSSELGMTFTGVDTMASYEEVLHLLRYRNWHARSLLDRKFKLICSELNGRYISNEFKVEVNVIHTANPMEHANHMAAQPQFVHPEHRSFVDLSGHNLANPHPFAVVPSTATVVIVVCVSFLVFMIILGVFRIRAAHRRTMRDQDTGKENEMDWDDSALTITVNPMETYEDQHSSEEEEEEEEEEESEDGEEEDDITSAESESSEEEEGEQGDPQNATRQQQLEWDDSTLSY", "output": "Postsynaptic adhesion molecule that binds to presynaptic neurexins to mediate both excitatory and inhibitory synapse formation (By similarity). Promotes synapse development by acting as a cell adhesion molecule at the postsynaptic membrane, which associates with neurexin-alpha at the presynaptic membrane (By similarity). Also functions as a cargo in axonal anterograde transport by acting as a molecular adapter that promotes KLC1 association with vesicles . Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation .; "}]}
+{"id": "function_test_7", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MALSQSVPFSATELLLASAIFCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANVIGAMCFGQHFPESSDEMLSLVKNTHEFVETASSGNPLDFFPILRYLPNPALQRFKAFNQRFLWFLQKTVQEHYQDFDKNSVRDITGALFKHSKKGPRASGNLIPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSVPPGVKVDLTPIYGLTMKHARCEHVQARLRFSIN", "output": "A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins . Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase) . Catalyzes the hydroxylation of carbon-hydrogen bonds . Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E2 . Metabolizes cholesterol toward 25-hydroxycholesterol, a physiological regulator of cellular cholesterol homeostasis . May act as a major enzyme for all-trans retinoic acid biosynthesis in the liver. Catalyzes two successive oxidative transformation of all-trans retinol to all-trans retinal and then to the active form all-trans retinoic acid . Primarily catalyzes stereoselective epoxidation of the last double bond of polyunsaturated fatty acids (PUFA), displaying a strong preference for the (R,S) stereoisomer . Catalyzes bisallylic hydroxylation and omega-1 hydroxylation of PUFA . May also participate in eicosanoids metabolism by converting hydroperoxide species into oxo metabolites (lipoxygenase-like reaction, NADPH-independent) . Plays a role in the oxidative metabolism of xenobiotics. Catalyzes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin . Metabolizes caffeine via N3-demethylation (Probable)."}]}
+{"id": "function_test_8", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGVKASQTGFVVLVLLQCCSAYKLVCYYTSWSQYREGDGSCFPDALDRFLCTHIIYSFANISNDHIDTWEWNDVTLYGMLNTLKNRNPNLKTLLSVGGWNFGSQRFSKIASNTQSRRTFIKSVPPFLRTHGFDGLDLAWLYPGRRDKQHFTTLIKEMKAEFIKEAQPGKKQLLLSAALSAGKVTIDSSYDIAKISQHLDFISIMTYDFHGAWRGTTGHHSPLFRGQEDASPDRFSNTDYAVGYMLRLGAPASKLVMGIPTFGRSFTLASSETGVGAPISGPGIPGRFTKEAGTLAYYEICDFLRGATVHRILGQQVPYATKGNQWVGYDDQESVKSKVQYLKDRQLAGAMVWALDLDDFQGSFCGQDLRFPLTNAIKDALAAT", "output": "Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung."}]}
+{"id": "function_test_9", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSSGAPQKSSPMASGAEETPGFLDTLLQDFPALLNPEDPLPWKAPGTVLSQEEVEGELAELAMGFLGSRKAPPPLAAALAHEAVSQLLQTDLSEFRKLPREEEEEEEDDDEEEKAPVTLLDAQSLAQSFFNRLWEVAGQWQKQVPLAARASQRQWLVSIHAIRNTRRKMEDRHVSLPSFNQLFGLSDPVNRAYFAVFDGHGGVDAARYAAVHVHTNAARQPELPTDPEGALREAFRRTDQMFLRKAKRERLQSGTTGVCALIAGATLHVAWLGDSQVILVQQGQVVKLMEPHRPERQDEKARIEALGGFVSHMDCWRVNGTLAVSRAIGDVFQKPYVSGEADAASRALTGSEDYLLLACDGFFDVVPHQEVVGLVQSHLTRQQGSGLRVAEELVAAARERGSHDNITVMVVFLRDPQELLEGGNQGEGDPQAEGRRQDLPSSLPEPETQAPPRS", "output": "Dephosphorylates and concomitantly deactivates CaM-kinase II activated upon autophosphorylation, and CaM-kinases IV and I activated upon phosphorylation by CaM-kinase kinase. Promotes apoptosis."}]}
+{"id": "function_test_10", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPVLSARRRELADHAGSGRRSGPSPTARSGPHLSALRAQPARAAHLSGRGTYVRRDTAGGGPGQARPLGPPGTSLLGRGARRSGEGWCPGAFESGARAARPPSRVEPRLATAASREGAGLPRAEVAAGSGRGARSGEWGLAAAGAWETMHHCKRYRSPEPDPYLSYRWKRRRSYSREHEGRLRYPSRREPPPRRSRSRSHDRLPYQRRYRERRDSDTYRCEERSPSFGEDYYGPSRSRHRRRSRERGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERSFHTSRNPSR", "output": "Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Phosphorylates SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells."}]}
+{"id": "function_test_11", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAAGCLLALTLTLFQSLLIGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDIYEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASNEVVYYNAKDDLDPEKNDSEPGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVLNELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRRRPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQDVSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIMLFTDGGEERAQEIFNKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIRINTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNITGQFENKTNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKPIGVGIPTINLRKRRPNIQNPKSQEPVTLDFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSLALVLPTYSFYYIKAKLEETITQARYSETLKPDNFEESGYTFIAPRDYCNDLKISDNNTEFLLNFNEFIDRKTPNNPSCNADLINRVLLDAGFTNELVQNYWSKQKNIKGVKARFVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGAYESGIMVSKAVEIYIQGKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVILDDGGFLLMANHDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAAPKQGAGHRSAYVPSVADILQIGWWATAAAWSILQQFLLSLTFPRLLEAVEMEDDDFTASLSKQSCITEQTQYFFDNDSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIMVESKGTCPCDTRLLIQAEQTSDGPNPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWYIIGIQFLLLWLVSGSTHRLL", "output": "The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel . Plays an important role in excitation-contraction coupling (By similarity)."}]}
+{"id": "function_test_12", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGRWAWVPSPWPPPGLGPFLLLLLLLLLLPRGFQPQPGGNRTESPEPNATATPAIPTILVTSVTSETPATSAPEAEGPQSGGLPPPPRAVPSSSSPQAQALTEDGRPCRFPFRYGGRMLHACTSEGSAHRKWCATTHNYDRDRAWGYCVEATPPPGGPAALDPCASGPCLNGGSCSNTQDPQSYHCSCPRAFTGKDCGTEKCFDETRYEYLEGGDRWARVRQGHVEQCECFGGRTWCEGTRHTACLSSPCLNGGTCHLIVATGTTVCACPPGFAGRLCNIEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRIRPPRRLVAPS", "output": "Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form."}]}
+{"id": "function_test_13", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MELDLSPPHLSSSPEDLCPAPGTPPGTPRPPDTPLPEEVKRSQPLLIPTTGRKLREEERRATSLPSIPNPFPELCSPPSQSPILGGPSSARGLLPRDASRPHVVKVYSEDGACRSVEVAAGATARHVCEMLVQRAHALSDETWGLVECHPHLALERGLEDHESVVEVQAAWPVGGDSRFVFRKNFAKYELFKSSPHSLFPEKMVSSCLDAHTGISHEDLIQNFLNAGSFPEIQGFLQLRGSGRKLWKRFFCFLRRSGLYYSTKGTSKDPRHLQYVADVNESNVYVVTQGRKLYGMPTDFGFCVKPNKLRNGHKGLRIFCSEDEQSRTCWLAAFRLFKYGVQLYKNYQQAQSRHLHPSCLGSPPLRSASDNTLVAMDFSGHAGRVIENPREALSVALEEAQAWRKKTNHRLSLPMPASGTSLSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLNRGILPCLLRHCCTRVAL", "output": "Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granules. Binds to the 5'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress (By similarity)."}]}
+{"id": "function_test_14", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKKMYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSFFDSKTRSTIVYEILKRTTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQRHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRKQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPCNHHNTKACPDSLGSPAPSHAYHGGVL", "output": "Calcium-activated chloride channel (CaCC) . Plays a role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development. Required for CFTR activation by enhancing endoplasmic reticulum Ca(2+) store release and is also required for CFTR membrane expression . Required for basal and ATP-dependent mucus secretion in airways and intestine, probably by controlling exocytosis of mucus-filled granules by providing Ca(2+) to an apical signaling compartment (By similarity). Contributes to airway mucus expression induced by interleukins IL3 and IL8 and by the asthma-associated protein CLCA1 and is required for expression of mucin MUC5AC . However, was shown in another study not to be required for MUC5AC expression . Plays a role in the propagation of Ca(2+) waves in Kolliker's organ in the cochlea and contributes to the refinement of auditory brainstem circuitries prior to hearing onset (By similarity). In vomeronasal sensory neurons, modulates spontaneous firing patterns in the absence of stimuli as well as the firing pattern of pheromone-evoked activity (By similarity). Responsible for calcium-activated chloride channel activity in type I taste cells of the vallate papillae (By similarity). Acts as a heat sensor in nociceptive neurons (By similarity). In dorsal root ganglion neurons, plays a role in mediating non-histaminergic Mas-related G-protein coupled receptor (MRGPR)-dependent itching, acting as a downstream effector of MRGPRs (By similarity). In the developing brain, required for the Ca(2+)-dependent process extension of radial glial cells (By similarity).; "}]}
+{"id": "function_test_15", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDPECAQLLPALCAVLVDPRQPVADDTCLEKLLDWFKTVTEGESSVVLLQEHPCLVELLSHVLKVQDLSSGVLSFSLRLAGTFAAQENCFQYLQQGELLPGLFGEPGPLGRATWAVPTVRSGWIQGLRSLAQHPSALRFLADHGAVDTIFSLQGDSSLFVASAASQLLVHVLALSMRGGAEGQPCLPGGDWPACAQKIMDHVEESLCSAATPKVTQALNVLTTTFGRCQSPWTEALWVRLSPRVACLLERDPIPAAHSFVDLLLCVARSPVFSSSDGSLWETVARALSCLGPTHMGPLALGILKLEHCPQALRTQAFQVLLQPLACVLKATVQAPGPPGLLDGTADDATTVDTLLASKSSCAGLLCRTLAHLEELQPLPQRPSPWPQASLLGATVTVLRLCDGSAAPASSVGGHLCGTLAGCVRVQRAALDFLGTLSQGTGPQELVTQALAVLLECLESPGSSPTVLKKAFQATLRWLLSSPKTPGCSDLGPLIPQFLRELFPVLQKRLCHPCWEVRDSALEFLTQLSRHWGGQADFRCALLASEVPQLALQLLQDPESYVRASAVTAMGQLSSQGLHAPTSPEHAEARQSLFLELLHILSVDSEGFPRRAVMQVFTEWLRDGHADAAQDTEQFVATVLQAASRDLDWEVRAQGLELALVFLGQTLGPPRTHCPYAVALPEVAPAQPLTEALRALCHVGLFDFAFCALFDCDRPVAQKSCDLLLFLRDKIASYSSLREARGSPNTASAEATLPRWRAGEQAQPPGDQEPEAVLAMLRSLDLEGLRSTLAESSDHVEKSPQSLLQDMLATGGFLQGDEADCY", "output": "Involved in DNA damage response; activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress . Plays a role in regulating mitochondrial function and cell proliferation . Required for protein stability of MTOR and MTOR-related proteins, and cell cycle progress by growth factors ."}]}
+{"id": "function_test_16", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAAPSGVHLLVRRGSHRIFSSPLNHIYLHKQSSSQQRRNFFFRRQRDISHSIVLPAAVSSAHPVPKHIKKPDYVTTGIVPDWGDSIEVKNEDQIQGLHQACQLARHVLLLAGKSLKVDMTTEEIDALVHREIISHNAYPSPLGYGGFPKSVCTSVNNVLCHGIPDSRPLQDGDIINIDVTVYYNGYHGDTSETFLVGNVDECGKKLVEVARRCRDEAIAACRAGAPFSVIGNTISHITHQNGFQVCPHFVGHGIGSYFHGHPEIWHHANDSDLPMEEGMAFTIEPIITEGSPEFKVLEDAWTVVSLDNQRSAQFEHTVLITSRGAQILTKLPHEA", "output": "Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed (By similarity). May play a role in colon tumorigenesis."}]}
+{"id": "function_test_17", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRLPWELLVLQSFILCLADDSTLHGPIFIQEPSPVMFPLDSEEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMDFRYSVVEGSLLINNPNKTQDAGTYQCTATNSFGTIVSREAKLQFAYLDNFKTRTRSTVSVRRGQGMVLLCGPPPHSGELSYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVGNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARRHKSNGILEIPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQPNWIQKINDIHVAMEENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEITDTTAQLSWRPGPDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPYGKMIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWRHEDKEENARKIRTVGNQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRWNRQSSTSVIETNKTSVELSLPFDEDYIIEIKPFSDGGDGSSSEQIRIPKISNAYARGSGASTSNACTLSAISTIMISLTARSSL", "output": "Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity. May be involved in synaptogenesis."}]}
+{"id": "function_test_18", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MWRAKLRRGTCEPAVKGSPSACYSPSSPVQVLEDSTYFSPDFQLYSGRHETSALTVEATSSIREKVVEDPLCNFHSPNFLRISEVEMRGSEDAAAGTVLQRLIQEQLRYGTPTENMNLLAIQHQATGSAGPAHPTNNFSSTENLTQEDPQMVYQSARQEPQGQEHQVDNTVMEKQVRSTQPQQNNEELPTYEEAKAQSQFFRGQQQQQQQQGAVGHGYYMAGGTSQKSRTEGRPTVNRANSGQAHKDEALKELKQGHVRSLSERIMQLSLERNGAKQHLPGSGNGKGFKVGGGPSPAQPAGKVLDPRGPPPEYPFKTKQMMSPVSKTQEHGLFYGDQHPGMLHEMVKPYPAPQPVRTDVAVLRYQPPPEYGVTSRPCQLPFPSTMQQHSPMSSQTSSASGPLHSVSLPLPLPMALGAPQPPPAASPSQQLGPDAFAIVERAQQMVEILTEENRVLHQELQGYYDNADKLHKFEKELQRISEAYESLVKSTTKRESLDKAMRNKLEGEIRRLHDFNRDLRDRLETANRQLSSREYEGHEDKAAEGHYASQNKEFLKEKEKLEMELAAVRTASEDHRRHIEILDQALSNAQARVIKLEEELREKQAYVEKVEKLQQALTQLQSACEKREQMERRLRTWLERELDALRTQQKHGNGQPANMPEYNAPALLELVREKEERILALEADMTKWEQKYLEESTIRHFAMNAAATAAAERDTTIINHSRNGSYGESSLEAHIWQEEEEVVQANRRCQDMEYTIKNLHAKIIEKDAMIKVLQQRSRKDAGKTDSSSLRPARSVPSIAAATGTHSRQTSLTSSQLAEEKKEEKTWKGSIGLLLGKEHHEHASAPLLPPPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRLSTTPAHSPVLKHPAAKGTAEKLENSPGHGKSPDHRGRVSSLLHKPEFPDGEMMEVLI", "output": "Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus."}]}
+{"id": "function_test_19", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAIEGGERTCGVHELICIRKVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLES", "output": "May be involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Is Ca(2+)-independent."}]}
+{"id": "function_test_20", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPEKRLTAEPPTITEEEFEDSLATDDFLVDYFNEFLSLPTFSEAIRFNADYGVFEVANDAPQFLEKQLKKILQNQQPRNPIYDVVRKGKNEVKPVQMNAPDEDETINVNYNIMCLSREEGIKWIKKERLPAFLESDCYFEYRLAKLVSQVRWSKSGMNFTVGSNFSPWIVKKPPSLPPPATEEDNLVIMKKFYVSLGEASYTQTKDWFALAKQSQQTVSTFSLPCCVPYNKLKSPAISSVSENFIFDDGVHPRTKKDPSKTNKLISEFEEEEGEEEEVSVSLQDTPSQALLRVYLEKKQDVDESLTMHFSTCEEFLSSYIYFILRGAIQQIVGKPVGETPDYINFNNITKVSFDDCFESIHGKNFLSELVQTTKERSEEIEQTSLSSKNESAGPESRADWCISHRTYDIGNRKEFERFKKFIKGTLGERYWWLWMDIERLKVLKDPGRHQRHLEKMKKCYLVSNGDYYLSAEILSKFKLLDGSQWNEEHLRNIQSEVLKPLLLYWAPRFCVTHSASTKYASAELKFWHLRQAKPRKDIDPFPQMATLLPLRPKSCIPQIPEIQKEEFSLSQPPKSPNKSPEVKTATQKPWKRELLYPGSSKDDVIEKGSKYMSESSKVIHLTSFTDISECLKPQLDRRYAYTEEPRVKTVSDVGALGGSDMENLLQSLYVENRAGFFFTKFCEHSGNKLWKNSVYFWFDLQAYHQLFYQETLQPFKVCKQAQYLFATYVAPSATLDIGLQQEKKKEIYMKIQPPFEDLFDTAEEYILLLLLEPWTKMVKSDQIAYKKVELVEETRQLDSTYFRKLQALHKETFSKKAEDTTCEIGTGILSLSNVSKRTEYWDNVPAEYKHFKFSDLLNNKLEFEHFRQFLETHSSSMDLMCWTDIEQFRRITYRDRNQRKAKSIYIKNKYLNKKYFFGPNSPASLYQQNQVMHLSGGWGKILHEQLDAPVLVEIQKHVQNRLENVWLPLFLASEQFAARQKIKVQMKDIAEELLLQKAEKKIGVWKPVESKWISSSCKIIAFRKALLNPVTSRQFQRFVALKGDLLENGLLFWQEVQKYKDLCHSHCDESVIQKKITTIINCFINSSIPPALQIDIPVEQAQKIIEHRKELGPYVFREAQMTIFGVLFKFWPQFCEFRKNLTDENIMSVLERRQEYNKQKKKLAVLEDEKSGKDGIKQYANTSVPAIKTALLSDSFLGLQPYGRQPTWCYSKYIEALEQERILLKIQEELEKKLFAGLQPLTNFKASSSTMSLKKNMSAHSSQK", "output": "Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form."}]}
+{"id": "function_test_21", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSRDPGSGGWEEAPRAAAALCTLYHEAGQRLRRLQDQLAARDALIARLRARLAALEGDAAPSLVDALLEQVARFREQLRRQEGGAAEAQMRQEIERLTERLEEKEREMQQLLSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQSVIEKLQEENRLLKQKVTHVEDLNAKWQRYNASRDEYVRGLHAQLRGLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSREPDAGRIHAGSKTAKYLAADALELMVPGGWRPGTGSQQPEPPAEGGHPGAAQRGQGDLQCPHCLQCFSDEQGEELLRHVAECCQ", "output": "Inhibits NF-kappa-B activation by blocking the interaction of RIPK1 with its downstream effector NEMO/IKBKG. Forms a ternary complex with NFKB1 and MAP3K8 but appears to function upstream of MAP3K8 in the TLR4 signaling pathway that regulates MAP3K8 activation. Involved in activation of the MEK/ERK signaling pathway during innate immune response; this function seems to be stimulus- and cell type specific. Required for stability of MAP3K8. Involved in regulation of apoptosis in endothelial cells; promotes TEK agonist-stimulated endothelial survival. May act as transcriptional coactivator when translocated to the nucleus. Enhances CHUK-mediated NF-kappa-B activation involving NF-kappa-B p50-p65 and p50-c-Rel complexes."}]}
+{"id": "function_test_22", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MELHILEHRVRVLSVARPGLWLYTHPLIKLLFLPRRSRCKFFSLTETPEDYTLMVDEEGFKELPPSEFLQVAEATWLVLNVSSHSGAAVQAAGVTKIARSVIAPLAEHHVSVLMLSTYQTDFILVREQDLSVVIHTLAQEFDIYREVGGEPVPVTRDDSSNGFPRTQHGPSPTVHPIQSPQNRFCVLTLDPETLPAIATTLIDVLFYSHSTPKEAASSSPEPSSITFFAFSLIEGYISIVMDAETQKKFPSDLLLTSSSGELWRMVRIGGQPLGFDECGIVAQIAGPLAAADISAYYISTFNFDHALVPEDGIGSVIEVLQRRQEGLAS", "output": "Functions as an intracellular arginine sensor within the amino acid-sensing branch of the TORC1 signaling pathway . As a homodimer or a heterodimer with CASTOR2, binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1 . Binding of arginine to CASTOR1 allosterically disrupts the interaction of CASTOR1-containing dimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway ."}]}
+{"id": "function_test_23", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEEFRRSYSRLCRESGAEPQEAVLQQLHQLPRGRLDLATQSLTVETCRALGKLLPRETLCTELVLSDCMLSEEGATLLLRGLCANTVLRFLDLKGNNLRAAGAEALGKLLQQNKSIQSLTLEWNSLGTWDDAFATFCGGLAANGALQRLDLRNNQISHKGAEELALALKGNTTLQQLDLRWNNVGLLGGRALMNCLPSNRTLWRLDLAGNNIPGDVLRAVEQAMGHSQDRLTTFQENQARTHVLSKEVQHLREEKSKQFLDLMETIDKQREEMAKSSRASAARVGQLQEALNERHSIINALKAKLQMTEAALALSEQKAQDLGELLATAEQEQLSLSQRQAKELKLEQQEAAERESKLLRDLSAANEKNLLLQNQVDELERKFRCQQEQLFQTRQEMTSMSAELKMRAIQAEERLDMEKRRCRQSLEDSESLRIKEVEHMTRHLEESEKAMQERVQRLEAARLSLEEELSRVKAAALSERGQAEEELIKAKSQARLEEQQRLAHLEDKLRLLAQARDEAQGACLQQKQVVAEAQTRVSQLGLQVEGLRRRLEELQQELSLKDQERVAEVSRVRVELQEQNGRLQAELAAQEALREKAAALERQLKVMASDHREALLDRESENASLREKLRLREAEIARIRDEEAQRASFLQNAVLAYVQASPVRTLSPPK", "output": "Component of the proteinaceous fiber-like linker between two centrioles, required for centrosome cohesion."}]}
+{"id": "function_test_24", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVGEGPYLISDLDQRGRRRSFAERYDPSLKTMIPVRPCARLAPNPVDDAGLLSFATFSWLTPVMVKGYRQRLTVDTLPPLSTYDSSDTNAKRFRVLWDEEVARVGPEKASLSHVVWKFQRTRVLMDIVANILCIIMAAIGPVILIHQILQQTERTSGKVWVGIGLCIALFATEFTKVFFWALAWAINYRTAIRLKVALSTLVFENLVSFKTLTHISVGEVLNILSSDSYSLFEAALFCPLPATIPILMVFCAAYAFFILGPTALIGISVYVIFIPVQMFMAKLNSAFRRSAILVTDKRVQTMNEFLTCIRLIKMYAWEKSFTNTIQDIRRRERKLLEKAGFVQSGNSALAPIVSTIAIVLTLSCHILLRRKLTAPVAFSVIAMFNVMKFSIAILPFSIKAMAEANVSLRRMKKILIDKSPPSYITQPEDPDTVLLLANATLTWEHEASRKSTPKKLQNQKRHLCKKQRSEAYSERSPPAKGATGPEEQSDSLKSVLHSISFVVRKGKILGICGNVGSGKSSLLAALLGQMQLQKGVVAVNGTLAYVSQQAWIFHGNVRENILFGEKYDHQRYQHTVRVCGLQKDLSNLPYGDLTEIGERGLNLSGGQRQRISLARAVYSDRQLYLLDDPLSAVDAHVGKHVFEECIKKTLRGKTVVLVTHQLQFLESCDEVILLEDGEICEKGTHKELMEERGRYAKLIHNLRGLQFKDPEHLYNAAMVEAFKESPAEREEDAGIIVLAPGNEKDEGKESETGSEFVDTKVPEHQLIQTESPQEGTVTWKTYHTYIKASGGYLLSLFTVFLFLLMIGSAAFSNWWLGLWLDKGSRMTCGPQGNRTMCEVGAVLADIGQHVYQWVYTASMVFMLVFGVTKGFVFTKTTLMASSSLHDTVFDKILKSPMSFFDTTPTGRLMNRFSKDMDELDVRLPFHAENFLQQFFMVVFILVILAAVFPAVLLVVASLAVGFFILLRIFHRGVQELKKVENVSRSPWFTHITSSMQGLGIIHAYGKKESCITYHLLYFNCALRWFALRMDVLMNILTFTVALLVTLSFSSISTSSKGLSLSYIIQLSGLLQVCVRTGTETQAKFTSVELLREYISTCVPECTHPLKVGTCPKDWPSRGEITFRDYQMRYRDNTPLVLDSLNLNIQSGQTVGIVGRTGSGKSSLGMALFRLVEPASGTIFIDEVDICILSLEDLRTKLTVIPQDPVLFVGTVRYNLDPFESHTDEMLWQVLERTFMRDTIMKLPEKLQAEVTENGENFSVGERQLLCVARALLRNSKIILLDEATASMDSKTDTLVQNTIKDAFKGCTVLTIAHRLNTVLNCDHVLVMENGKVIEFDKPEVLAEKPDSAFAMLLAAEVRL", "output": "Probable transporter, its substrate specificity is unknown."}]}
+{"id": "function_test_25", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLKLSGEGLRDSYHSRRDQIALKNLQSDVTEAKSDFTKETLASQNTKMISSIVISQMIDENKSRENRASLPLPCAIAQSRAHHAKQSLANRSGVNIHRAFALLPGRLGIPAPSDERGPEAELPPKEERPCGGPRRGFASITITARRVGPPARALVWGTAGDSLCPKCRAEDTLFQAPPALANGAHPGRHQRSFACTEFSRNSSVVRLKVPEAHTGLCERRKYWVTHADDKETSFSPDTPLSGKSPLVFSSCVHLRVSQQCPDSIYYVDKSLSVPIEPPQIASPKMHRSVLSLNLNCSSHRLTADGVDGLVNREPISEALKQELLEGDQDLVGQRWNPGLQESHLKETPSLRRVHLGTGACPWSGSFPLENTELANVGANQVTVRKGEKDHTTHCHASDHANQLSIHIPGWSYRAVHTKVFSGSSKRQQGEVCMTVSAPPVEQKPTRHFLPIGDSSPSDDCLSRDLSEPTERRHQSFLKPRILFPGFLCPLQDVCASLQEDNGVQIESKFPKGDYTCCDLVVKIKECKKSEDPTTPEPSPAAPSPAPRDGAGSPGLSEDCSESQQTPARSLTLQEALEVRKPQFISRSQERLKKLEHMVQQRKAQRKEDLRQKQSLLPIRTSKKQFTIPHPLSDNLFKPKERCISEKEMHMRSKRIYDNLPEVKKKKEEQRKRVILQSNRLRAEVFKKQLLDQLLQRNAV", "output": "Tumor suppressor that is required to sustain G2/M checkpoint after DNA damage. Acts as a p53/TP53 activator by inhibiting MDM2 binding to p53/TP53 and stimulating non-proteolytic polyubiquitination of p53/TP53. Exhibits ubiquitin ligase (E3) activity and assemble ubiquitin polymers through 'Lys-11'- (K11-), 'Lys-29'- (K29-) and 'Lys-63'- (K63)-linkages, independently of the ubiquitin-conjugating enzyme (E2). Promotes p53/TP53-dependent transcription of CDKN1A/p21, leading to robust checkpoint response. Mediates CDKN1A/p21 protein stability in a ubiquitin-independent manner. Interacts with HDAC1 and prevents binding of HDAC1 to CDKN1A/p21 and facilitates the acetylation and stabilization of CDKN1A/p21 (By similarity). May have a role in the assembly of primary cilia (Probable)."}]}
+{"id": "function_test_26", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGNAGSMDSQQTDFRAHNVPLKLPMPEPGELEERFAIVLNAMNLPPDKARLLRQYDNEKKWELICDQERFQVKNPPHTYIQKLKGYLDPAVTRKKFRRRVQESTQVLRELEISLRTNHIGWVREFLNEENKGLDVLVEYLSFAQYAVTFDFESVESTVESSVDKSKPWSRSIEDLHRGSNLPSPVGNSVSRSGRHSALRYNTLPSRRTLKNSRLVSKKDDVHVCIMCLRAIMNYQYGFNMVMSHPHAVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHEIILSAFDNFKEVCGEKQRFEKLMEHFRNEDNNIDFMVASMQFINIVVHSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTESDKLQVQIQAYLDNVFDVGALLEDAETKNAALERVEELEENISHLSEKLQDTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGTIKIQKKGDGDIAILPVVASGTLSMGSEVVAGNSVGPTMGAASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLPGPAAETVPAPPLAPPLPSAPPLPGTSSPTVVFNSGLAAVKIKKPIKTKFRMPVFNWVALKPNQINGTVFNEIDDERILEDLNVDEFEEIFKTKAQGPAIDLSSSKQKIPQKGSNKVTLLEANRAKNLAITLRKAGKTADEICKAIHVFDLKTLPVDFVECLMRFLPTENEVKVLRLYERERKPLENLSDEDRFMMQFSKIERLMQKMTIMAFIGNFAESIQMLTPQLHAIIAASVSIKSSQKLKKILEIILALGNYMNSSKRGAVYGFKLQSLDLLLDTKSTDRKQTLLHYISNVVKEKYHQVSLFYNELHYVEKAAAVSLENVLLDVKELQRGMDLTKREYTMHDHNTLLKEFILNNEGKLKKLQDDAKIAQDAFDDVVKYFGENPKTTPPSVFFPVFVRFVKAYKQAEEENELRKKQEQALMEKLLEQEALMEQQDPKSPSHKSKRQQQELIAELRRRQVKDNRHVYEGKDGAIEDIITVLKTVPFTARTAKRGSRFFCEPVLTEEYHY", "output": "Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics."}]}
+{"id": "function_test_27", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTTKRSLFVRLVPCRCLRGEEETVTTLDYSHCSLEQVPKEIFTFEKTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKNGIQEFPENIKNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFGRLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFIPGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPLIPLQKETDSETQKMVLTNYMFPQQPRTEDVMFISDNESFNPSLWEEQRKQRAQVAFECDEDKDEREAPPREGNLKRYPTPYPDELKNMVKTVQTIVHRLKDEETNEDSGRDLKPHEDQQDINKDVGVKTSESTTTVKSKVDEREKYMIGNSVQKISEPEAEISPGSLPVTANMKASENLKHIVNHDDVFEESEELSSDEEMKMAEMRPPLIETSINQPKVVALSNNKKDDTKETDSLSDEVTHNSNQNNSNCSSPSRMSDSVSLNTDSSQDTSLCSPVKQTHIDINSKIRQEDENFNSLLQNGDILNSSTEEKFKAHDKKDFNLPEYDLNVEERLVLIEKSVDSTATADDTHKLDHINMNLNKLITNDTFQPEIMERSKTQDIVLGTSFLSINSKEETEHLENGNKYPNLESVNKVNGHSEETSQSPNRTEPHDSDCSVDLGISKSTEDLSPQKSGPVGSVVKSHSITNMEIGGLKIYDILSDNGPQQPSTTVKITSAVDGKNIVRSKSATLLYDQPLQVFTGSSSSSDLISGTKAIFKFDSNHNPEEPNIIRGPTSGPQSAPQIYGPPQYNIQYSSSAAVKDTLWHSKQNPQIDHASFPPQLLPRSESTENQSYAKHSANMNFSNHNNVRANTAYHLHQRLGPARHGEMWAISPNDRLIPAVTRSTIQRQSSVSSTASVNLGDPGSTRRAQIPEGDYLSYREFHSAGRTPPMMPGSQRPLSARTYSIDGPNASRPQSARPSINEIPERTMSVSDFNYSRTSPSKRPNARVGSEHSLLDPPGKSKVPRDWREQVLRHIEAKKLEKKHPQTSSSGDPCQDGIFISGQQNYSSATLSHKDVPPDSLMKMPLSNGQMGQPLRPQANYSQIHHPPQASVARHPSREQLIDYLMLKVAHQPPYTQPHCSPRQGHELAKQEIRVRVEKDPELGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASKLLQPGDKIIQANGYSFINIEHGQAVSLLKTFQNTVELIIVREVSS", "output": "Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated 'Tyr-1248' of receptor ERBB2, it may contribute to stabilize this unphosphorylated state . Inhibits NOD2-dependent NF-kappa-B signaling and pro-inflammatory cytokine secretion ."}]}
+{"id": "function_test_28", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MATTAAPAGGARNGAGPEWGGFEENIQGGGSAVIDMENMDDTSGSSFEDMGELHQRLREEEVDADAADAAAAEEEDGEFLGMKGFKGQLSRQVADQMWQAGKRQASRAFSLYANIDILRPYFDVEPAQVRSRLLESMIPIKMVNFPQKIAGELYGPLMLVFTLVAILLHGMKTSDTIIREGTLMGTAIGTCFGYWLGVSSFIYFLAYLCNAQITMLQMLALLGYGLFGHCIVLFITYNIHLHALFYLFWLLVGGLSTLRMVAVLVSRTVGPTQRLLLCGTLAALHMLFLLYLHFAYHKVVEGILDTLEGPNIPPIQRVPRDIPAMLPAARLPTTVLNATAKAVAVTLQSH", "output": "Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis."}]}
+{"id": "function_test_29", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAAAAGGGSCPGPGSARGRFPGRPRGAGGGGGRGGRGNGAERVRVALRRGGGATGPGGAEPGEDTALLRLLGLRRGLRRLRRLWAGPRVQRGRGRGRGRGWGPSRGCVPEEESSDGESDEEEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRDRQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLPSHHGKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERLAKKGRTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAHPGPEEQDSLLQRKSARRCVKQRPSYDIFEDSDDSEPGGPPAPRRRTPRENELPLPEPEEQSRPRKPTLQPVLQLKARRRLDKDALAPGPFASFPNGWTGKQKSPDGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGPPMVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGRGSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGATPGKNWDVEWSGDYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLSDEDYEILSGLPDSVLYTCGPCAGAAQPRWREALSGALQGGLRQVLQGLLSSKVVGPLLLCTQCGPDGKQLHPGPCGLQAVSQRFEDGHYKSVHSFMEDMVGILMRHSEEGETPDRRAGGQMKGLLLKLLESAFGWFDAHDPKYWRRSTRLPNGVLPNAVLPPSLDHVYAQWRQQEPETPESGQPPGDPSAAFQGKDPAAFSHLEDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFEENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKVFCQKHTDLLDGKEIVNPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIRIDSLGTLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRCRILEYRPWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSPDDKENQAPKRTGPHLRFEISSEDGFSVEAESLEGAWRTLIEKVQEARGHARLRHLSFSGMSGARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEGQE", "output": "Histone methyltransferase that catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4) via a non-processive mechanism. Part of chromatin remodeling machinery predominantly forms H3K4me1 and H3K4me2 methylation marks at active chromatin sites where transcription and DNA repair take place . Likely plays a redundant role with KMT2C in enriching H3K4me1 marks on primed and active enhancer elements . Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2 . Plays an important role in controlling bulk H3K4me during oocyte growth and preimplantation development (By similarity). Required during the transcriptionally active period of oocyte growth for the establishment and/or maintenance of bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption of meiosis, oocyte survival and normal zygotic genome activation (By similarity)."}]}
+{"id": "function_test_30", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MHFSTVTRDMEAFTASSLSSLGAAGGFPGAASPGADPYGPREPPPPPPRYDPCAAAAPGAPGPPPPPHAYPFAPAAGAATSAAAEPEGPGASCAAAAKAPVKKNAKVAGVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRDCDPEDWPRNHRPGALPLMSAFARSRNPVASPTQPSGTEKGGHVLKDKEVKAETSRNTPEREVELLRDAGGCVNLGLPCPAECQPFNTQGLVAGRTAGDRLC", "output": "Probable transcriptional regulator involved in developmental processes (By similarity). Binds to the palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence . Is required for normal development of the pharyngeal arch arteries (By similarity)."}]}
+{"id": "function_test_31", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNVFRILGDLSHLLAMILLLGKIWRSKCCKGISGKSQILFALVFTTRYLDLFTNFISIYNTVMKVVFLLCAYVTVYMIYGKFRKTFDSENDTFRLEFLLVPVIGLSFLENYSFTLLEILWTFSIYLESVAILPQLFMISKTGEAETITTHYLFFLGLYRALYLANWIRRYQTENFYDQIAVVSGVVQTIFYCDFFYLYVTKVLKGKKLSLPMPI", "output": "Receptor for the C-terminal sequence motif K-D-E-L that is present on endoplasmic reticulum resident proteins and that mediates their recycling from the Golgi back to the endoplasmic reticulum."}]}
+{"id": "function_test_32", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAPDPVAAETAAQGPTPRYFTWDEVAQRSGCEERWLVIDRKVYNISEFTRRHPGGSRVISHYAGQDATDPFVAFHINKGLVKKYMNSLLIGELSPEQPSFEPTKNKELTDEFRELRATVERMGLMKANHVFFLLYLLHILLLDGAAWLTLWVFGTSFLPFLLCAVLLSAVQAQAGWLQHDFGHLSVFSTSKWNHLLHHFVIGHLKGAPASWWNHMHFQHHAKPNCFRKDPDINMHPFFFALGKILSVELGKQKKKYMPYNHQHKYFFLIGPPALLPLYFQWYIFYFVIQRKKWVDLAWMITFYVRFFLTYVPLLGLKAFLGLFFIVRFLESNWFVWVTQMNHIPMHIDHDRNMDWVSTQLQATCNVHKSAFNDWFSGHLNFQIEHHLFPTMPRHNYHKVAPLVQSLCAKHGIEYQSKPLLSAFADIIHSLKESGQLWLDAYLHQ", "output": "[Isoform 1]: Acts as a front-end fatty acyl-coenzyme A (CoA) desaturase that introduces a cis double bond at carbon 5 located between a preexisting double bond and the carboxyl end of the fatty acyl chain. Involved in biosynthesis of highly unsaturated fatty acids (HUFA) from the essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3) precursors. Specifically, desaturates dihomo-gamma-linoleoate (DGLA) (20:3n-6) and eicosatetraenoate (ETA) (20:4n-3) to generate arachidonate (AA) (20:4n-6) and eicosapentaenoate (EPA) (20:5n-3), respectively . As a rate limiting enzyme for DGLA (20:3n-6) and AA (20:4n-6)-derived eicosanoid biosynthesis, controls the metabolism of inflammatory lipids like prostaglandin E2, critical for efficient acute inflammatory response and maintenance of epithelium homeostasis. Contributes to membrane phospholipid biosynthesis by providing AA (20:4n-6) as a major acyl chain esterified into phospholipids. In particular, regulates phosphatidylinositol-4,5-bisphosphate levels, modulating inflammatory cytokine production in T-cells (By similarity). Also desaturates (11E)-octadecenoate (trans-vaccenoate)(18:1n-9), a metabolite in the biohydrogenation pathway of LA (18:2n-6) (By similarity).; "}]}
+{"id": "function_test_33", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKDSENKGASSPDMEPSYGGGLFDMVKGGAGRLFSNLKDNLKDTLKDTSSRVIQSVTSYTKGDLDFTYVTSRIIVMSFPLDNVDIGFRNQVDDIRSFLDSRHLDHYTVYNLSPKSYRTAKFHSRVSECSWPIRQAPSLHNLFAVCRNMYNWLLQNPKNVCVVHCLDGRAASSILVGAMFIFCNLYSTPGPAIRLLYAKRPGIGLSPSHRRYLGYMCDLLADKPYRPHFKPLTIKSITVSPIPFFNKQRNGCRPYCDVLIGETKIYSTCTDFERMKEYRVQDGKIFIPLNITVQGDVVVSMYHLRSTIGSRLQAKVTNTQIFQLQFHTGFIPLDTTVLKFTKPELDACDVPEKYPQLFQVTLDVELQPHDKVIDLTPPWEHYCTKDVNPSILFSSHQEHQDTLALGGQAPIDIPPDNPRHYGQSGFFASLCWQDQKSEKSFCEEDHAALVNQESEQSDDELLTLSSPHGNANGDKPHGVKKPSKKQQEPAAPPPPEDVDLLGLEGSAMSNSFSPPAAPPTNSELLSDLFGGGGAAGPTQAGQSGVEDVFHPSGPASTQSTPRRSATSTSASPTLRVGEGATFDPFGAPSKPSGQDLLGSFLNTSSASSDPFLQPTRSPSPTVHASSTPAVNIQPDVSGGWDWHAKPGGFGMGSKSAATSPTGSSHGTPTHQSKPQTLDPFADLGTLGSSSFASKPTTPTGLGGGFPPLSSPQKASPQPMGGGWQQGGAYNWQQPQPKPQPSMPHSSPQNRPNYNVSFSAMPGGQNERGKGSSNLEGKQKAADFEDLLSGQGFNAHKDKKGPRTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMHTVLWAGETKWKPVGMADLVTPEQVKKVYRKAVLVVHPDKATGQPYEQYAKMIFMELNDAWSEFENQGQKPLY", "output": "Recruits HSPA8/HSC70 to clathrin-coated vesicles and promotes uncoating of clathrin-coated vesicles. Plays a role in clathrin-mediated endocytosis in neurons (By similarity)."}]}
+{"id": "function_test_34", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGNNFSSIPSLPRGNPSRAPRGHPQNLKDSIGGPFPVTSHRCHHKQKHCPAVLPSGGLPATPLLFHPHTKGSQILMDLSHKAVKRQASFCNAITFSNRPVLIYEQVRLKITKKQCCWSGALRLGFTSKDPSRIHPDSLPKYACPDLVSQSGFWAKALPEEFANEGNIIAFWVDKKGRVFHRINDSAVMLFFSGVRTADPLWALVDVYGLTRGVQLLDSELVLPDCLRPRSFTALRRPSLRREADDARLSVSLCDLNVPGADGDEAAPAAGCPIPQNSLNSQHSRALPAQLDGDLRFHALRAGAHVRILDEQTVARVEHGRDERALVFTSRPVRVAETIFVKVTRSGGARPGALSFGVTTCDPGTLRPADLPFSPEALVDRKEFWAVCRVPGPLHSGDILGLVVNADGELHLSHNGAAAGMQLCVDASQPLWMLFGLHGTITQIRILGSTILAERGIPSLPCSPASTPTSPSALGSRLSDPLLSTCSSGPLGSSAGGTAPNSPVSLPESPVTPGLGQWSDECTICYEHAVDTVIYTCGHMCLCYACGLRLKKALHACCPICRRPIKDIIKTYRSS", "output": "Plays a role in hippocampal-dependent synaptic plasticity, learning and memory. Involved in the formation of spines and functional synaptic contacts by modulating the translational activity of the cytoplasmic polyadenylation element-binding protein CPEB3. Promotes ubiquitination of CPEB3, and hence induces CPEB3-dependent mRNA translation activation of glutamate receptor GRIA1 and GRIA2. Can function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1 (in vitro), thereby regulating the Notch pathway. Acts as a tumor suppressor; inhibits malignant cell transformation of medulloblastoma (MB) cells by inhibiting the Notch signaling pathway."}]}
+{"id": "function_test_35", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEDSHKSTTSETAPQPGSAVQGAHISHIAQQVSSLSESEESQDSSDSIGSSQKAHGILARRPSYRKILKDLSSEDTRGRKGDGENSGVSAAVTSMSVPTPIYQTSSGQYIAIAPNGALQLASPGTDGVQGLQTLTMTNSGSTQQGTTILQYAQTSDGQQILVPSNQVVVQTASGDMQTYQIRTTPSATSLPQTVVMTSPVTLTSQTTKTDDPQLKREIRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKTLKDLYSNKSV", "output": "This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation."}]}
+{"id": "function_test_36", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEKKWKYCAVYYIIQIHFVKGVWEKTVNTEENVYATLGSDVNLTCQTQTVGFFVQMQWSKVTNKIDLIAVYHPQYGFYCAYGRPCESLVTFTETPENGSKWTLHLRNMSCSVSGRYECMLVLYPEGIQTKIYNLLIQTHVTADEWNSNHTIEIEINQTLEIPCFQNSSSKISSEFTYAWSVENSSTDSWVLLSKGIKEDNGTQETLISQNHLISNSTLLKDRVKLGTDYRLHLSPVQIFDDGRKFSCHIRVGPNKILRSSTTVKVFAKPEIPVIVENNSTDVLVERRFTCLLKNVFPKANITWFIDGSFLHDEKEGIYITNEERKGKDGFLELKSVLTRVHSNKPAQSDNLTIWCMALSPVPGNKVWNISSEKITFLLGSEISSTDPPLSVTESTLDTQPSPASSVSPARYPATSSVTLVDVSALRPNTTPQPSNSSMTTRGFNYPWTSSGTDTKKSVSRIPSETYSSSPSGAGSTLHDNVFTSTARAFSEVPTTANGSTKTNHVHITGIVVNKPKDGMSWPVIVAALLFCCMILFGLGVRKWCQYQKEIMERPPPFKPPPPPIKYTCIQEPNESDLPYHEMETL", "output": "May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation."}]}
+{"id": "function_test_37", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEPRPTAPSSGAPGLAGVGETPSAAALAAARVELPGTAVPSVPEDAAPASRDGGGVRDEGPAAAGDGLGRPLGPTPSQSRFQVDLVSENAGRAAAAAAAAAAAAAAAGAGAGAKQTPADGEASGESEPAKGSEEAKGRFRVNFVDPAASSSAEDSLSDAAGVGVDGPNVSFQNGGDTVLSEGSSLHSGGGGGSGHHQHYYYDTHTNTYYLRTFGHNTMDAVPRIDHYRHTAAQLGEKLLRPSLAELHDELEKEPFEDGFANGEESTPTRDAVVTYTAESKGVVKFGWIKGVLVRCMLNIWGVMLFIRLSWIVGQAGIGLSVLVIMMATVVTTITGLSTSAIATNGFVRGGGAYYLISRSLGPEFGGAIGLIFAFANAVAVAMYVVGFAETVVELLKEHSILMIDEINDIRIIGAITVVILLGISVAGMEWEAKAQIVLLVILLLAIGDFVIGTFIPLESKKPKGFFGYKSEIFNENFGPDFREEETFFSVFAIFFPAATGILAGANISGDLADPQSAIPKGTLLAILITTLVYVGIAVSVGSCVVRDATGNVNDTIVTELTNCTSAACKLNFDFSSCESSPCSYGLMNNFQVMSMVSGFTPLISAGIFSATLSSALASLVSAPKIFQALCKDNIYPAFQMFAKGYGKNNEPLRGYILTFLIALGFILIAELNVIAPIISNFFLASYALINFSVFHASLAKSPGWRPAFKYYNMWISLLGAILCCIVMFVINWWAALLTYVIVLGLYIYVTYKKPDVNWGSSTQALTYLNALQHSIRLSGVEDHVKNFRPQCLVMTGAPNSRPALLHLVHDFTKNVGLMICGHVHMGPRRQAMKEMSIDQAKYQRWLIKNKMKAFYAPVHADDLREGAQYLMQAAGLGRMKPNTLVLGFKKDWLQADMRDVDMYINLFHDAFDIQYGVVVIRLKEGLDISHLQGQEELLSSQEKSPGTKDVVVSVEYSKKSDLDTSKPLSEKPITHKVEEEDGKTATQPLLKKESKGPIVPLNVADQKLLEASTQFQKKQGKNTIDVWWLFDDGGLTLLIPYLLTTKKKWKDCKIRVFIGGKINRIDHDRRAMATLLSKFRIDFSDIMVLGDINTKPKKENIIAFEEIIEPYRLHEDDKEQDIADKMKEDEPWRITDNELELYKTKTYRQIRLNELLKEHSSTANIIVMSLPVARKGAVSSALYMAWLEALSKDLPPILLVRGNHQSVLTFYS", "output": "Cation-chloride cotransporter which mediates the electroneutral transport of chloride, potassium and/or sodium ions across the membrane . Plays a vital role in the regulation of ionic balance and cell volume."}]}
+{"id": "function_test_38", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNRGGGSPSAAANYLLCTNCRKVLRKDKRIRVSQPLTRGPSAFIPEKEVVQANTVDERTNFLVEEYSTSGRLDNITQVMSLHTQYLESFLRSQFYMLRMDGPLPLPYRHYIAIMAAARHQCSYLINMHVDEFLKTGGIAEWLNGLEYVPQRLKNLNEINKLLAHRPWLITKEHIQKLVKTGENNWSLPELVHAVVLLAHYHALASFVFGSGINPERDPEISNGFRLISVNNFCVCDLANDNNIENASLSGSNFGIVDSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSDFEDDMIITSDVSRYIEDPGFGYEDFARRGEEHLPTFRAQDYTWENHGFSLVNRLYSDIGHLLDEKFRMVYNLTYNTMATHEDVDTTMLRRALFNYVHCMFGIRYDDYDYGEVNQLLERSLKVYIKTVTCYPERTTKRMYDSYWRQFKHSEKVHVNLLLMEARMQAELLYALRAITRHLT", "output": "May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway . May also regulate the insulin-receptor signaling pathway through activation of TORC2 (By similarity). This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses (By similarity). May prevent the accumulation of reactive oxygen species (ROS) through the alkylhydroperoxide reductase activity born by the N-terminal domain of the protein (By similarity)."}]}
+{"id": "function_test_39", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAEVGEDSGARALLALRSAPCSPVLCAAAAAAAFPAAAPPPAPAQPQPPPGPPPPPPPPLPPGAIAGAGSSGGSSGVSGDSAVAGAAPALVAAAAASVRQSPGPALARLEGREFEFLMRQPSVTIGRNSSQGSVDLSMGLSSFISRRHLQLSFQEPHFYLRCLGKNGVFVDGAFQRRGAPALQLPKQCTFRFPSTAIKIQFTSLYHKEEAPASPLRPLYPQISPLKIHIPEPDLRSMVSPVPSPTGTISVPNSCPASPRGAGSSSYRFVQNVTSDLQLAAEFAAKAASEQQADTSGGDSPKDESKPPFSYAQLIVQAISSAQDRQLTLSGIYAHITKHYPYYRTADKGWQNSIRHNLSLNRYFIKVPRSQEEPGKGSFWRIDPASEAKLVEQAFRKRRQRGVSCFRTPFGPLSSRSAPASPTHPGLMSPRSGGLQTPECLSREGSPIPHDPEFGSKLASVPEYRYSQSAPGSPVSAQPVIMAVPPRPSSLVAKPVAYMPASIVTSQQPAGHAIHVVQQAPTVTMVRVVTTSANSANGYILTSQGAAGGSHDAAGAAVLDLGSEARGLEEKPTIAFATIPAAGGVIQTVASQMAPGVPGHTVTILQPATPVTLGQHHLPVRAVTQNGKHAVPTNSLAGNAYALTSPLQLLATQASSSAPVVVTRVCEVGPKEPAAAVAATATTTPATATTASASASSTGEPEVKRSRVEEPSGAVTTPAGVIAAAGPQGPGTGE", "output": "Transcriptional regulator involved in different processes such as glucose metabolism, aerobic glycolysis, muscle cell differentiation and autophagy (By similarity). Recognizes and binds the forkhead DNA sequence motif (5'-GTAAACA-3') and can both act as a transcription activator or repressor, depending on the context . Together with FOXK2, acts as a key regulator of metabolic reprogramming towards aerobic glycolysis, a process in which glucose is converted to lactate in the presence of oxygen (By similarity). Acts by promoting expression of enzymes for glycolysis (such as hexokinase-2 (HK2), phosphofructokinase, pyruvate kinase (PKLR) and lactate dehydrogenase), while suppressing further oxidation of pyruvate in the mitochondria by up-regulating pyruvate dehydrogenase kinases PDK1 and PDK4 (By similarity). Probably plays a role in gluconeogenesis during overnight fasting, when lactate from white adipose tissue and muscle is the main substrate (By similarity). Involved in mTORC1-mediated metabolic reprogramming: in response to mTORC1 signaling, translocates into the nucleus and regulates the expression of genes associated with glycolysis and downstream anabolic pathways, such as HIF1A, thereby regulating glucose metabolism (By similarity). Together with FOXK2, acts as a negative regulator of autophagy in skeletal muscle: in response to starvation, enters the nucleus, binds the promoters of autophagy genes and represses their expression, preventing proteolysis of skeletal muscle proteins (By similarity). Acts as a transcriptional regulator of the myogenic progenitor cell population in skeletal muscle (By similarity). Binds to the upstream enhancer region (CCAC box) of myoglobin (MB) gene, regulating the myogenic progenitor cell population (By similarity). Promotes muscle progenitor cell proliferation by repressing the transcriptional activity of FOXO4, thereby inhibiting myogenic differentiation (By similarity). Involved in remodeling processes of adult muscles that occur in response to physiological stimuli (By similarity). Required to correct temporal orchestration of molecular and cellular events necessary for muscle repair (By similarity). Represses myogenic differentiation by inhibiting MEFC activity (By similarity). Positively regulates Wnt/beta-catenin signaling by translocating DVL into the nucleus . Reduces virus replication, probably by binding the interferon stimulated response element (ISRE) to promote antiviral gene expression ."}]}
+{"id": "function_test_40", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLSEVLLVSAPGKVILHGEHAVVHGKVALAVSLNLRTFLRLQPHSNGKVDLSLPNIGIKRAWDVARLQSLDTSFLEQGDVTTPTSEQVEKLKEVAGLPDDCAVTERLAVLAFLYLYLSICRKQRALPSLDIVVWSELPPGAGLGSSAAYSVCLAAALLTVCEEIPNPLKDGDCVNRWTKEDLELINKWAFQGERMIHGNPSGVDNAVSTWGGALRYHQGKISSLKRSPALQILLTNTKVPRNTRALVAGVRNRLLKFPEIVAPLLTSIDAISLECERVLGEMGEAPAPEQYLVLEELIDMNQHHLNALGVGHASLDQLCQVTRARGLHSKLTGAGGGGCGITLLKPGLEQPEVEATKQALTSCGFDCLETSIGAPGVSIHSATSLDSRVQQALDGL", "output": "Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis ."}]}
+{"id": "function_test_41", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGAARGSPARPRRLPLLSVLLLPLLGGTQTAIVFIKQPSSQDALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTCLPPKGLPEPSVWWEHAGVRLPTHGRVYQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEFDKEATVPCSATGREKPTIKWERADGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSVGAAVAYIIAVLGLMFYCKKRCKAKRLQKQPEGEEPEMECLNGGPLQNGQPSAEIQEEVALTSLGSGPAATNKRHSTSDKMHFPRSSLQPITTLGKSEFGEVFLAKAQGLEEGVAETLVLVKSLQSKDEQQQLDFRRELEMFGKLNHANVVRLLGLCREAEPHYMVLEYVDLGDLKQFLRISKSKDEKLKSQPLSTKQKVALCTQVALGMEHLSNNRFVHKDLAARNCLVSAQRQVKVSALGLSKDVYNSEYYHFRQAWVPLRWMSPEAILEGDFSTKSDVWAFGVLMWEVFTHGEMPHGGQADDEVLADLQAGKARLPQPEGCPSKLYRLMQRCWALSPKDRPSFSEIASALGDSTVDSKP", "output": "Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis."}]}
+{"id": "function_test_42", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIAAQAKLVYHLNKYYNEKCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLNEMDNRYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRDRYVVQITPAFKCTGIWPRSAAHWPLPHIPWPGPNRVAEVKAEGFNLLSKECHSLAGKQSSAESDAWVLQFAEAENRLQMGGCRKKCLSILKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALENAAKQTWRLAREILTNPKSLEKL", "output": "Putative nucleotidyltransferase required for several aspects of embryonic development including normal development of the eye . It is unclear whether it displays nucleotidyltransferase activity in vivo . Binds single-stranded RNA (ssRNA) ."}]}
+{"id": "function_test_43", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MARDYDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQERFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRILVGNKNDDPERKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQQQQQNDVVKLTKNSKRKKRCC", "output": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in the process of endocytosis and is an essential rate-limiting regulator of the fast recycling pathway back to the plasma membrane. During cytokinesis, required for the postfurrowing terminal steps, namely for intercellular bridge stability and abscission, possibly by controlling phosphatidylinositol 4,5-bis phosphate (PIP2) and SEPT2 localization at the intercellular bridge. May indirectly regulate neurite outgrowth. Together with TBC1D13 may be involved in regulation of insulin-induced glucose transporter SLC2A4/GLUT4 translocation to the plasma membrane in adipocytes."}]}
+{"id": "function_test_44", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNNLSFSELCCLFCCPPCPGKIASKLAFLPPDPTYTLMCDESGSRWTLHLSERADWQYSSREKDAIECFMTRTSKGNRIACMFVRCSPNAKYTLLFSHGNAVDLGQMSSFYIGLGSRINCNIFSYDYSGYGASSGKPTEKNLYADIEAAWLALRTRYGIRPENVIIYGQSIGTVPSVDLAARYESAAVILHSPLTSGMRVAFPDTKKTYCFDAFPNIDKISKITSPVLIIHGTEDEVIDFSHGLALFERCQRPVEPLWVEGAGHNDVELYGQYLERLKQFVSQELVNL", "output": "Hydrolyzes fatty acids from S-acylated cysteine residues in proteins . Has depalmitoylating activity towards DLG4/PSD95 . Has depalmitoylating activity towards GAP43 (By similarity). Has depalmitoylating activity towards MAP6 (By similarity). Has depalmitoylating activity towards NRAS ."}]}
+{"id": "function_test_45", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLPDCLSAEGELRCRRLLAGATARLRARPASAAVLVPLCSVRGVPALLYTLRSSRLTGRHKGDVSFPGGKCDPADQDVVHTALRETREELGLAVPEEHVWGLLRPVYDPQKATVVPVLAGVGPLDPQSLRPNSEEVDEVFALPLAHLLQTQNQGYTHFCRGGHFRYTLPVFLHGPHRVWGLTAVITEFALQLLAPGTYQPRLAGLTCSGAEGLARPKQPLASPCQASSTPGLNKGL", "output": "Acyl-CoA diphosphatase that mediates the hydrolysis of a wide range of CoA and CoA esters yielding 3',5'-ADP and the corresponding 4'-phosphopantetheine derivative as products (By similarity). Hydrolyzes short- and medium-chain acyl-CoAs, exhibiting the highest activity toward free CoA, hexanoyl-CoA, and octanoyl-CoA and the lowest activity against acetyl-CoA (By similarity). Exhibits decapping activity towards dpCoA-capped RNAs in vitro (By similarity)."}]}
+{"id": "function_test_46", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDTSDLFASCRKGDVGRVRYLLEQRDVEVNVRDKWDSTPLYYACLCGHEELVLYLLANGARCEANTFDGERCLYGALSDPIRRALRDYKQVTASCRRRDYYDDFLQRLLEQGIHSDVVFVVHGKPFRVHRCVLGARSAYFANMLDTKWKGKSVVVLRHPLINPVAFGALLQYLYTGRLDIGVEHVSDCERLAKQCQLWDLLSDLEAKCEKVSEFVASKPGTCVKVLTIEPPPADPRLREDMALLADCALPPELRGDLWELPFPCPDGFNSCPDICFRVAGCSFLCHKAFFCGRSDYFRALLDDHFRESEEPATSGGPPAVTLHGISPDVFTHVLYYMYSDHTELSPEAAYDVLSVADMYLLPGLKRLCGRSLAQMLDEDTVVGVWRVAKLFRLARLEDQCTEYMAKVIEKLVEREDFVEAVKEEAAAVAARQETDSIPLVDDIRFHVASTVQTYSAIEEAQQRLRALEDLLVSIGLDC", "output": "May act as a mediator of the PTEN growth-suppressive signaling pathway. May play a role in developmental processes."}]}
+{"id": "function_test_47", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDLSNNTMSLSVRTPGLSRRLSSQSVIGRPRGMSASSVGSGYGGSAFGFGASCGGGFSAASMFGSSSGFGGGSGSSMAGGLGAGYGRALGGGSFGGLGMGFGGSPGGGSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTGTADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQGVEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMDAAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTDLRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAERQNVDHQRLLNVKARLELEIETYRRLLDGEAQGDGLEESLFVTDSKSQAQSTDSSKDPTKTRKIKTVVQEMVNGEVVSSQVQEIEELM", "output": "Involved in corneal epithelium organization, integrity and corneal keratin expression."}]}
+{"id": "function_test_48", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGVPTALEAGSWRWGSLLFALFLAASLGPVAAFKVATPYSLYVCPEGQNVTLTCRLLGPVDKGHDVTFYKTWYRSSRGEVQTCSERRPIRNLTFQDLHLHHGGHQAANTSHDLAQRHGLESASDHHGNFSITMRNLTLLDSGLYCCLVVEIRHHHSEHRVHGAMELQVQTGKDAPSNCVVYPSSSQDSENITAAALATGACIVGILCLPLILLLVYKQRQAASNRRAQELVRMDSNIQGIENPGFEASPPAQGIPEAKVRHPLSYVAQRQPSESGRHLLSEPSTPLSPPGPGDVFFPSLDPVPDSPNFEVI", "output": "Immunoregulatory receptor which inhibits the T-cell response . May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling (By similarity). May stimulate MMP14-mediated MMP2 activation ."}]}
+{"id": "function_test_49", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MVSSAQMGFNLQALLEQLSQDELSKFKYLITTFSLAHELQKIPHKEVDKADGKQLVEILTTHCDSYWVEMASLQVFEKMHRMDLSERAKDEVREAALKSFNKRKPLSLGITRKERPPLDVDEMLERFKTEAQAFTETKGNVICLGKEVFKGKKPDKDNRCRYILKTKFREMWKSWPGDSKEVQVMAERYKMLIPFSNPRVLPGPFSYTVVLYGPAGLGKTTLAQKLMLDWAEDNLIHKFKYAFYLSCRELSRLGPCSFAELVFRDWPELQDDIPHILAQARKILFVIDGFDELGAAPGALIEDICGDWEKKKPVPVLLGSLLNRVMLPKAALLVTTRPRALRDLRILAEEPIYIRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPTCLTRTGLFLRFLCSRFPQGAQLRGALRTLSLLAAQGLWAQTSVLHREDLERLGVQESDLRLFLDGDILRQDRVSKGCYSFIHLSFQQFLTALFYTLEKEEEEDRDGHTWDIGDVQKLLSGVERLRNPDLIQAGYYSFGLANEKRAKELEATFGCRMSPDIKQELLRCDISCKGGHSTVTDLQELLGCLYESQEEELVKEVMAQFKEISLHLNAVDVVPSSFCVKHCRNLQKMSLQVIKENLPENVTASESDAEVERSQDDQHMLPFWTDLCSIFGSNKDLMGLAINDSFLSASLVRILCEQIASDTCHLQRVVFKNISPADAHRNLCLALRGHKTVTYLTLQGNDQDDMFPALCEVLRHPECNLRYLGLVSCSATTQQWADLSLALEVNQSLTCVNLSDNELLDEGAKLLYTTLRHPKCFLQRLSLENCHLTEANCKDLAAVLVVSRELTHLCLAKNPIGNTGVKFLCEGLRYPECKLQTLVLWNCDITSDGCCDLTKLLQEKSSLLCLDLGLNHIGVKGMKFLCEALRKPLCNLRCLWLWGCSIPPFSCEDLCSALSCNQSLVTLDLGQNPLGSSGVKMLFETLTCSSGTLRTLRLKIDDFNDELNKLLEEIEEKNPQLIIDTEKHHPWAERPSSHDFMI", "output": "Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature pro-inflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of pro-inflammatory caspases."}]}
+{"id": "function_test_50", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKMLLLLHCLGVFLSCSGHIQDEHPQYHSPPDVVIPVRITGTTRGMTPPGWLSYILPFGGQKHIIHIKVKKLLFSKHLPVFTYTDQGAILEDQPFVQNNCYYHGYVEGDPESLVSLSTCFGGFQGILQINDFAYEIKPLAFSTTFEHLVYKMDSEEKQFSTMRSGFMQNEITCRMEFEEIDNSTQKQSSYVGWWIHFRIVEIVVVIDNYLYIRYERNDSKLLEDLYVIVNIVDSILDVIGVKVLLFGLEIWTNKNLIVVDDVRKSVHLYCKWKSENITPRMQHDTSHLFTTLGLRGLSGIGAFRGMCTPHRSCAIVTFMNKTLGTFSIAVAHHLGHNLGMNHDEDTCRCSQPRCIMHEGNPPITKFSNCSYGDFWEYTVERTKCLLETVHTKDIFNVKRCGNGVVEEGEECDCGPLKHCAKDPCCLSNCTLTDGSTCAFGLCCKDCKFLPSGKVCRKEVNECDLPEWCNGTSHKCPDDFYVEDGIPCKERGYCYEKSCHDRNEQCRRIFGAGANTASETCYKELNTLGDRVGHCGIKNATYIKCNISDVQCGRIQCENVTEIPNMSDHTTVHWARFNDIMCWSTDYHLGMKGPDIGEVKDGTECGIDHICIHRHCVHITILNSNCSPAFCNKRGICNNKHHCHCNYLWDPPNCLIKGYGGSVDSGPPPKRKKKKKFCYLCILLLIVLFILLCCLYRLCKKSKPIKKQQDVQTPSAKEEEKIQRRPHELPPQSQPWVMPSQSQPPVTPSQSHPQVMPSQSQPPVTPSQSQPRVMPSQSQPPVMPSQSHPQLTPSQSQPPVTPSQRQPQLMPSQSQPPVTPS", "output": "May be involved in spermatogenesis and fertilization. Seems to be a non catalytic metalloprotease-like protein."}]}
+{"id": "function_test_51", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGLFGKTQEKPPKELVNEWSLKIRKEMRVVDRQIRDIQREEEKVKRSVKDAAKKGQKDVCIVLAKEMIRSRKAVSKLYASKAHMNSVLMGMKNQLAVLRVAGSLQKSTEVMKAMQSLVKIPEIQATMRELSKEMMKAGIIEEMLEDTFESMDDQEEMEEEAEMEIDRILFEITAGALGKAPSKVTDALPEPEPPGAMAASEDEEEEEEALEAMQSRLATLRS", "output": "Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Selectively binds to phosphatidylinositol 3,5-bisphosphate PtdIns(3,5)P2 and PtdIns(3,4)P2 in preference to other phosphoinositides tested. Involved in late stages of cytokinesis. Plays a role in endosomal sorting/trafficking of EGF receptor. Isoform 2 prevents stress-mediated cell death and accumulation of reactive oxygen species when expressed in yeast cells."}]}
+{"id": "function_test_52", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEKMLAGCFLLILGQIVLLPAEARERSRGRSISRGRHARTHPQTALLESSCENKRADLVFIIDSSRSVNTHDYAKVKEFIVDILQFLDIGPDVTRVGLLQYGSTVKNEFSLKTFKRKSEVERAVKRMRHLSTGTMTGLAIQYALNIAFSEAEGARPLRENVPRVIMIVTDGRPQDSVAEVAAKARDTGILIFAIGVGQVDFNTLKSIGSEPHEDHVFLVANFSQIETLTSVFQKKLCTAHMCSTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQLCVNVPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECVNADGSYLCQCHEGFALNPDKKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKTCRRINYCALNKPGCEHECVNMEESYYCRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCLNTEDSFVCQCSEGFLINEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFVCQCFEGYILREDGKTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKRCRRKDVCKSTHHGCEHICVNNGNSYICKCSEGFVLAEDGRRCKKCTEGPIDLVFVIDGSKSLGEENFEVVKQFVTGIIDSLTISPKAARVGLLQYSTQVHTEFTLRNFNSAKDMKKAVAHMKYMGKGSMTGLALKHMFERSFTQGEGARPLSTRVPRAAIVFTDGRAQDDVSEWASKAKANGITMYAVGVGKAIEEELQEIASEPTNKHLFYAEDFSTMDEISEKLKKGICEALEDSDGRQDSPAGELPKTVQQPTESEPVTINIQDLLSCSNFAVQHRYLFEEDNLLRSTQKLSHSTKPSGSPLEEKHDQCKCENLIMFQNLANEEVRKLTQRLEEMTQRMEALENRLRYR", "output": "Involved in matrix assembly."}]}
+{"id": "function_test_53", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MQNEPLTPGYHGFPARDSQGNQEPTTTPDAMVQPFTTIPFPPPPQNGIPTEYGVPHTQDYAGQTGEHNLTLYGSTQAHGEQSSNSPSTQNGSLTTEGGAQTDGQQSQTQSSENSESKSTPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKMVTPYANGWKLSPVVGAVYGPELYAASSFQADVSLGNDAAVPLSGRGGINTYIPLISLPLVPGFPYPTAATTAAAFRGAHLRGRGRTVYGAVRAVPPTAIPAYPGVVYQDGFYGADLYGGYAAYRYAQPATATAATAAAAAAAAYSDGYGRVYTADPYHALAPAASYGVGAVASLYRGGYSRFAPY", "output": "RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis (By similarity). RNA-binding protein that seems to act as a coregulatory factor of ER-alpha."}]}
+{"id": "function_test_54", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRRRRAGGRTMVERASKFVLVVAGSVCFMLILYQYAGPGLSLGAPGGRAPPDDLDLFPTPDPHYEKKYYFPVRELERSLRFDMKGDDVIVFLHIQKTGGTTFGRHLVQNVRLEVPCDCRPGQKKCTCYRPNRRETWLFSRFSTGWSCGLHADWTELTNCVPGVLDRRDSAALRTPRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQEFMDCPYNLANNRQVRMLADLSLVGCYNLSFIPEGKRAQLLLESAKKNLRGMAFFGLTEFQRKTQYLFERTFNLKFIRPFMQYNSTRAGGVEVDEDTIRRIEELNDLDMQLYDYAKDLFQQRYQYKRQLERREQRLRSREERLLHRAKEALPREDADEPGRVPTEDYMSHIIEKW", "output": "6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. Critical for normal neuronal development where it may play a role in neuron branching. May also play a role in limb development. May prefer iduronic acid."}]}
+{"id": "function_test_55", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIPQFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDIINEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTEAEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQALGDVAGRGNEKKPSSVRALSIVLPIVLLVFLCLGVFLLWKNWRLKNINSINFDNPVYQKTTEDEVHICHNQDGYSYPSRQMVSLEDDVA", "output": "Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.; "}]}
+{"id": "function_test_56", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MYGKIIFVLLLSEIVSISASSTTGVAMHTSTSSSVTKSYISSQTNDTHKRDTYAATPRAHEVSEISVRTVYPPEEETGERVQLAHHFSEPEITLIIFGVMAGVIGTILLISYGIRRLIKKSPSDVKPLPSPDTDVPLSSVEIENPETSDQ", "output": "Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV)."}]}
+{"id": "function_test_57", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAPPPAPLLAPRPGETRPGCRKPGTVSFADVAVYFSPEEWGCLRPAQRALYRDVMQETYGHLGALGFPGPKPALISWMEQESEAWSPAAQDPEKGERLGGARRGDVPNRKEEEPEEVPRAKGPRKAPVKESPEVLVERNPDPAISVAPARAQPPKNAAWDPTTGAQPPAPIPSMDAQAGQRRHVCTDCGRRFTYPSLLVSHRRMHSGERPFPCPECGMRFKRKFAVEAHQWIHRSCSGGRRGRRPGIRAVPRAPVRGDRDPPVLFRHYPDIFEECG", "output": "May be involved in transcriptional regulation."}]}
+{"id": "function_test_58", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNVALQELGAGSNMVEYKRATLRDEDAPETPVEGGASPDAMEVGKGASPFSPGPSPGMTPGTPRSSGLFWRVTCPHLRSISGLCSRTMVGFQKGTRQLLGSRTQLELVLAGASLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLLSPLELSDSEPVVVYGMDYLQQVSELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW", "output": "Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May play a role in amyloid-beta processing (By similarity)."}]}
+{"id": "function_test_59", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MASEIHMTGPMCLIENTNGRLMANPEALKILSAITQPMVVVAIVGLYRTGKSYLMNKLAGKKKGFSLGSTVQSHTKGIWMWCVPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAVLLSSTFVYNSIGTINQQAMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVWTLRDFSLDLEADGQPLTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDRPVHRRKLAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIQVNGPRLESLVLTYVNAISSGDLPCMENAVLALAQIENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMRRRKACTIS", "output": "Interferon (IFN)-inducible GTPase that plays important roles in innate immunity against a diverse range of bacterial, viral and protozoan pathogens . Hydrolyzes GTP to GMP in two consecutive cleavage reactions: GTP is first hydrolyzed to GDP and then to GMP in a processive manner . Following infection, recruited to the pathogen-containing vacuoles or vacuole-escaped bacteria and promotes both autophagy and inflammasome assembly . Promotes host defense against bacterial infections by regulating bacteriolytic peptide generation via its interaction with ubiquitin-binding protein SQSTM1, which delivers monoubiquitinated proteins to autolysosomes for the generation of bacteriolytic peptides (By similarity). Also acts as a positive regulator of inflammasome assembly by promoting the release of inflammasome ligands from bacteria . Acts by promoting lysis of pathogen-containing vacuoles, releasing pathogens into the cytosol (By similarity). Following pathogen release in the cytosol, promotes recruitment of proteins that mediate bacterial cytolysis: this liberates ligands that are detected by inflammasomes, such as lipopolysaccharide (LPS) that activates the non-canonical CASP4/CASP11 inflammasome or double-stranded DNA (dsDNA) that activates the AIM2 inflammasome . Confers protection to several pathogens, including the bacterial pathogens L.monocytogenes and M.bovis BCG as well as the protozoan pathogen T.gondii . Exhibits antiviral activity against influenza virus ."}]}
+{"id": "function_test_60", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSTRESFNPESYELDKSFRLTRFTELKGTGCKVPQDVLQKLLESLQENHFQEDEQFLGAVMPRLGIGMDTCVIPLRHGGLSLVQTTDYIYPIVDDPYMMGRIACANVLSDLYAMGVTECDNMLMLLGVSNKMTDRERDKVMPLIIQGFKDAAEEAGTSVTGGQTVLNPWIVLGGVATTVCQPNEFIMPDNAVPGDVLVLTKPLGTQVAVAVHQWLDIPEKWNKIKLVVTQEDVELAYQEAMMNMARLNRTAAGLMHTFNAHAATDITGFGILGHAQNLAKQQRNEVSFVIHNLPVLAKMAAVSKACGNMFGLMHGTCPETSGGLLICLPREQAARFCAEIKSPKYGEGHQAWIIGIVEKGNRTARIIDKPRIIEVAPQVATQNVNPTPGATS", "output": "Synthesizes selenophosphate from selenide and ATP."}]}
+{"id": "function_test_61", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAPGEKIKAKIKKNLPVTGPQAPTIKELMRWYCLNTNTHGCRRIVVSRGRLRRLLWIGFTLTAVALILWQCALLVFSFYTVSVSIKVHFRKLDFPAVTICNINPYKYSTVRHLLADLEQETREALKSLYGFPESRKRREAESWNSVSEGKQPRFSHRIPLLIFDQDEKGKARDFFTGRKRKVGGSIIHKASNVMHIESKQVVGFQLCSNDTSDCATYTFSSGINAIQEWYKLHYMNIMAQVPLEKKINMSYSAEELLVTCFFDGVSCDARNFTLFHHPMHGNCYTFNNRENETILSTSMGGSEYGLQVILYINEEEYNPFLVSSTGAKVIIHRQDEYPFVEDVGTEIETAMVTSIGMHLTESFKLSEPYSQCTEDGSDVPIRNIYNAAYSLQICLHSCFQTKMVEKCGCAQYSQPLPPAANYCNYQQHPNWMYCYYQLHRAFVQEELGCQSVCKEACSFKEWTLTTSLAQWPSVVSEKWLLPVLTWDQGRQVNKKLNKTDLAKLLIFYKDLNQRSIMESPANSIEMLLSNFGGQLGLWMSCSVVCVIEIIEVFFIDFFSIIARRQWQKAKEWWAWKQAPPCPEAPRSPQGQDNPALDIDDDLPTFNSALHLPPALGTQVPGTPPPKYNTLRLERAFSNQLTDTQMLDEL", "output": "Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception."}]}
+{"id": "function_test_62", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRNVNLEYQVKINAPKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTEECQEYSKDTLGRNIACWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTRNGYLQIEKLMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREWFVIVIMATICFILLILSLICKICHLWIKLFPPIPAPKSNIKDLFVTTNYEKAGSSETEIEVICYIEKPGVETLEDSVF", "output": "Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils . Acts by forming an heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5 . In unstimulated conditions, interacts constitutively with JAK2. Heterodimeric receptor activation leads to JAK2 stimulation and subsequent activation of the JAK-STAT pathway ."}]}
+{"id": "function_test_63", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAGHLASDFAFSPPPGGGGDGPGGPEPGWVDPRTWLSFQGPPGGPGIGPGVGPGSEVWGIPPCPPPYEFCGGMAYCGPQVGVGLVPQGGLETSQPEGEAGVGVESNSDGASPEPCTVTPGAVKLEKEKLEQNPEESQDIKALQKELEQFAKLLKQKRITLGYTQADVGLTLGVLFGKVFSQTTICRFEALQLSFKNMCKLRPLLQKWVEEADNNENLQEICKAETLVQARKRKRTSIENRVRGNLENLFLQCPKPTLQQISHIAQQLGLEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPLAPGPHFGTPGYGSPHFTALYSSVPFPEGEAFPPVSVTTLGSPMHSN", "output": "Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency."}]}
+{"id": "function_test_64", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAFAWWPCLILALLSSLAASGFPRSPFRLLGKRSLPEGVANGIEVYSTKINSKVTSRFAHNVVTMRAVNRADTAKEVSFDVELPKTAFITNFTLTIDGVTYPGNVKEKEVAKKQYEKAVSQGKTAGLVKASGRKLEKFTVSVNVAAGSKVTFELTYEELLKRHKGKYEMYLKVQPKQLVKHFEIEVDIFEPQGISMLDAEASFITNDLLGSALTKSFSGKKGHVSFKPSLDQQRSCPTCTDSLLNGDFTITYDVNRESPGNVQIVNGYFVHFFAPQGLPVVPKNVAFVIDISGSMAGRKLEQTKEALLRILEDMQEEDYLNFILFSGDVSTWKEHLVQATPENLQEARTFVKSMEDKGMTNINDGLLRGISMLNKAREEHRIPERSTSIVIMLTDGDANVGESRPEKIQENVRNAIGGKFPLYNLGFGNNLNYNFLENMALENHGFARRIYEDSDADLQLQGFYEEVANPLLTGVEMEYPENAILDLTQNTYQHFYDGSEIVVAGRLVDEDMNSFKADVKGHGATNDLTFTEEVDMKEMEKALQERDYIFGNYIERLWAYLTIEQLLEKRKNAHGEEKENLTARALDLSLKYHFVTPLTSMVVTKPEDNEDERAIADKPGEDAEATPVSPAMSYLTSYQPPQNPYYYVDGDPHFIIQIPEKDDALCFNIDEAPGTVLRLIQDAVTGLTVNGQITGDKRGSPDSKTRKTYFGKLGIANAQMDFQVEVTTEKITLWNRAVPSTFSWLDTVTVTQDGLSMMINRKNMVVSFGDGVTFVVVLHQVWKKHPVHRDFLGFYVVDSHRMSAQTHGLLGQFFQPFDFKVSDIRPGSDPTKPDATLVVKNHQLIVTRGSQKDYRKDASIGTKVVCWFVHNNGEGLIDGVHTDYIVPNLF", "output": "May act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes."}]}
+{"id": "function_test_65", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MASAGNAAEPQDRGGGGSGCIGAPGRPAGGGRRRRTGGLRRAAAPDRDYLHRPSYCDAAFALEQISKGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQLTKQRLVDADGIINPSAFYIYLTAWVSNDPVAYAASQANIRPHRPEWVHDKADYMPETRLRIPAAEPIEYAQFPFYLNGLRDTSDFVEAIEKVRTICSNYTSLGLSSYPNGYPFLFWEQYIGLRHWLLLFISVVLACTFLVCAVFLLNPWTAGIIVMVLALMTVELFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSFFGPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSN", "output": "Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis."}]}
+{"id": "function_test_66", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MHGGRSCGPRTRREPSSGEEAAPVTAMAAESALQVVEKLQARLAANPDPKKLLKYLKKLSTLPITVDILAETGVGKTVNSLRKHEHVGSFARDLVAQWKKLVPVERNAEPDEQDFEKSNSRKRPRDALQKEEEMEGDYQETWKATGSRSYSPDHRQKKHRKLSELERPHKVSHGHERRDERKRCHRMSPTYSSDPESSDYGHVQSPPSCTSPHQMYVDHYRSLEEDQEPIVSHQKPGKGHSNAFQDRLGASQERHLGEPHGKGVVSQNKEHKSSHKDKRPVDAKSDEKASVVSREKSHKALSKEENRRPPSGDNAREKPPSSGVKKEKDREGSSLKKKCLPPSEAASDNHLKKPKHRDPEKAKLDKSKQGLDSFDTGKGAGDLLPKVKEKGSNNLKTPEGKVKTNLDRKSLGSLPKVEETDMEDEFEQPTMSFESYLSYDQPRKKKKKIVKTSATALGDKGLKKNDSKSTGKNLDSVQKLPKVNKTKSEKPAGADLAKLRKVPDVLPVLPDLPLPAIQANYRPLPSLELISSFQPKRKAFSSPQEEEEAGFTGRRMNSKMQVYSGSKCAYLPKMMTLHQQCIRVLKNNIDSIFEVGGVPYSVLEPVLERCTPDQLYRIEEYNHVLIEETDQLWKVHCHRDFKEERPEEYESWREMYLRLQDAREQRLRVLTKNIQFAHANKPKGRQAKMAFVNSVAKPPRDVRRRQEKFGTGGAAVPEKIKIKPAPYPMGSSHASASSISFNPSPEEPAYDGPSTSSAHLAPVVSSTVSYDPRKPTVKKIAPMMAKTIKAFKNRFSRR", "output": "SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).; "}]}
+{"id": "function_test_67", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSPGLLTTRKEALMAFRDVAVAFTQKEWKLLSSAQRTLYREVMLENYSHLVSLGIAFSKPKLIEQLEQGDEPWREENEHLLDLCPEPRTEFQPSFPHLVAFSSSQLLRQYALSGHPTQIFPSSSAGGDFQLEAPRCSSEKGESGETEGPDSSLRKRPSRISRTFFSPHQGDPVEWVEGNREGGTDLRLAQRMSLGGSDTMLKGADTSESGAVIRGNYRLGLSKKSSLFSHQKHHVCPECGRGFCQRSDLIKHQRTHTGEKPYLCPECGRRFSQKASLSIHQRKHSGEKPYVCRECGRHFRYTSSLTNHKRIHSGERPFVCQECGRGFRQKIALLLHQRTHLEEKPFVCPECGRGFCQKASLLQHQSSHTGERPFLCLECGRSFRQQSLLLSHQVTHSGEKPYVCAECGHSFRQKVTLIRHQRTHTGEKPYLCPQCGRGFSQKVTLIGHQRTHTGEKPYLCPDCGRGFGQKVTLIRHQRTHTGEKPYLCPKCGRAFGFKSLLTRHQRTHSEEELYVDRVCGQGLGQKSHLISDQRTHSGEKPCICDECGRGFGFKSALIRHQRTHSGEKPYVCRECGRGFSQKSHLHRHRRTKSGHQLLPQEVF", "output": "May be involved in transcriptional regulation."}]}
+{"id": "function_test_68", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAKERCLKKSFQDSLEDIKKRMKEKRNKNLAEIGKRRSFIAAPCQIITNTSTLLKNYQDNNKMLVLALENEKSKVKEAQDIILQLRKECYYLTCQLYALKGKLTSQQTVEPAQNQEICSSGMDPNSDDSSRNLFVKDLPQIPLEETELPGQGESFQIEDQIPTIPQDTLGVDFDSGEAKSTDNVLPRTVSVRSSLKKHCNSICQFDSLDDFETSHLAGKSFEFERVGFLDPLVNMHIPENVQHNACQWSKDQVNLSPKLIQPGTFTKTKEDILESKSEQTKSKQRDTQERKREEKRKANRRKSKRMSKYKENKSENKKTVPQKKMHKSVSSNDAYNFNLEEGVHLTPFRQKVSNDSNREENNESEVSLCESSGSGDDSDDLYLPTCKYIQNPTSNSDRPVTRPLAKRALKYTDEKETEGSKPTKTPTTTPPETQQSPHLSLKDITNVSLYPVVKIRRLSLSPKKNKASPAVALPKRRCTASVNYKEPTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKKRALEVSPAKEAIFILYYVREFVSRFPDCRKCKLETHICLR", "output": "Plays a central role in chromosome cohesion during mitosis by preventing premature dissociation of cohesin complex from centromeres after prophase, when most of cohesin complex dissociates from chromosomes arms. May act by preventing phosphorylation of the STAG2 subunit of cohesin complex at the centromere, ensuring cohesin persistence at centromere until cohesin cleavage by ESPL1/separase at anaphase. Essential for proper chromosome segregation during mitosis and this function requires interaction with PPP2R1A. Its phosphorylated form is necessary for chromosome congression and for the proper attachment of spindle microtubule to the kinetochore. Necessary for kinetochore localization of PLK1 and CENPF. May play a role in the tension sensing mechanism of the spindle-assembly checkpoint by regulating PLK1 kinetochore affinity. Isoform 3 plays a role in maintaining centriole cohesion involved in controlling spindle pole integrity. Involved in centromeric enrichment of AUKRB in prometaphase."}]}
+{"id": "function_test_69", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLRLGLCAAALLCVCRPGAVRADCWLIEGDKGYVWLAICSQNQPPYETIPQHINSTVHDLRLNENKLKAVLYSSLNRFGNLTDLNLTKNEISYIEDGAFLGQSSLQVLQLGYNKLSNLTEGMLRGMSRLQFLFVQHNLIEVVTPTAFSECPSLISIDLSSNRLSRLDGATFASLASLMVCELAGNPFNCECDLFGFLAWLVVFNNVTKNYDRLQCESPREFAGYPLLVPRPYHSLNAITVLQAKCRNGSLPARPVSHPTPYSTDAQREPDENSGFNPDEILSVEPPASSTTDASAGPAIKLHHVTFTSATLVVIIPHPYSKMYILVQYNNSYFSDVMTLKNKKEIVTLDKLRAHTEYTFCVTSLRNSRRFNHTCLTFTTRDPVPGDLAPSTSTTTHYIMTILGCLFGMVIVLGAVYYCLRKRRMQEEKQKSVNVKKTILEMRYGADVDAGSIVHAAQKLGEPPVLPVSRMASIPSMIGEKLPTAKGLEAGLDTPKVATKGNYIEVRTGAGGDGLARPEDDLPDLENGQGSAAEISTIAKEVDKVNQIINNCIDALKLDSASFLGGGSSSGDPELAFECQSLPAAAAASSATGPGALERPSFLSPPYKESSHHPLQRQLSADAAVTRKTCSVSSSGSIKSAKVFSLDVPDHPAATGLAKGDSKYIEKGSPLNSPLDRLPLVPAGSGGGSGGGGGIHHLEVKPAYHCSEHRHSFPALYYEEGADSLSQRVSFLKPLTRSKRDSTYSQLSPRHYYSGYSSSPEYSSESTHKIWERFRPYKKHHREEVYMAAGHALRKKVQFAKDEDLHDILDYWKGVSAQQKL", "output": "Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes."}]}
+{"id": "function_test_70", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTTEVILHYRPCESDPTQLPKIAEKAIQDFPTRPLSRFIPWFPYDGSKLPLRPKRSPPVISEEAAEDVKQYLTISEHDAKSHSYDCTVDLLEFQPSLKKQHLTWSHTLKEQTNSGNLGKQSEKGKQHKRRSWSISLPSNNCTKNVSPLSKKLQDSLKALNLHSLYRARWTIEHTICNSQTLEDIWTKLNQIIRHNELPSCNATIQRHLGQIWVFCDIMYCEYVGSLLKGRLALTGKINLFVHKYGVIFSM", "output": "Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection. Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres."}]}
+{"id": "function_test_71", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTRGARLRSDARAQLNQLSLDGGTGSGQKGKCEEFPSSLSSVSPGLEAAALLLAVTMDPLETPIKDGILYQQHVKFGKKCWRKVWALLYAGGPSGVARLESWEVRDGGLGAAGDRSAGPGRRGERRVIRLADCVSVLPADGESCPRDTGAFLLTTTERSHLLAAQHRQAWMGPICQLAFPGTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPALLVLGPDAIQLREAKGTQALYSWPYHFLRKFGSDKGVFSFEAGRRCHSGEGLFAFSTPCAPDLCRAVAGAIARQRERLPELTRPQPCPLPRATSLPSLDTPGELREMPPGPEPPTSRKMHLAEPGPQSLPLLLGPEPNDLASGLYASVCKRASGPPGNEHLYENLCVLEASPTLHGGEPEPHEGPGSRSPTTSPIYHNGQDLSWPGPANDSTLEAQYRRLLELDQVEGTGRPDPQAGFKAKLVTLLSRERRKGPAPCDRP", "output": "DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function (By similarity)."}]}
+{"id": "function_test_72", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKSDSSTSAAPLRGLGGPLRSSEPVRAVPARAPAVDLLEEAADLLVVHLDFRAALETCERAWQSLANHAVAEEPAGTSLEVKCSLCVVGIQALAEMDRWQEVLSWVLQYYQVPEKLPPKVLELCILLYSKMQEPGAVLDVVGAWLQDPANQNLPEYGALAEFHVQRVLLPLGCLSEAEELVVGSAAFGEERRLDVLQAIHTARQQQKQEHSGSEEAQKPNLEGSVSHKFLSLPMLVRQLWDSAVSHFFSLPFKKSLLAALILCLLVVRFDPASPSSLHFLYKLAQLFRWIRKAAFSRLYQLRIRD", "output": "Peroxisomal docking factor that anchors PEX1 and PEX6 to peroxisome membranes . PEX26 is therefore required for the formation of the PEX1-PEX6 AAA ATPase complex, a complex that mediates the extraction of the PEX5 receptor from peroxisomal membrane ."}]}
+{"id": "function_test_73", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLLLGILTLAFAGRTAGGSEPEREVVVPIRLDPDINGRRYYWRGPEDSGDQGLIFQITAFQEDFYLHLTPDAQFLAPAFSTEHLGVPLQGLTGGSSDLRRCFYSGDVNAEPDSFAAVSLCGGLRGAFGYRGAEYVISPLPNASAPAAQRNSQGAHLLQRRGVPGGPSGDPTSRCGVASGWNPAILRALDPYKPRRAGFGESRSRRRSGRAKRFVSIPRYVETLVVADESMVKFHGADLEHYLLTLLATAARLYRHPSILNPINIVVVKVLLLRDRDSGPKVTGNAALTLRNFCAWQKKLNKVSDKHPEYWDTAILFTRQDLCGATTCDTLGMADVGTMCDPKRSCSVIEDDGLPSAFTTAHELGHVFNMPHDNVKVCEEVFGKLRANHMMSPTLIQIDRANPWSACSAAIITDFLDSGHGDCLLDQPSKPISLPEDLPGASYTLSQQCELAFGVGSKPCPYMQYCTKLWCTGKAKGQMVCQTRHFPWADGTSCGEGKLCLKGACVERHNLNKHRVDGSWAKWDPYGPCSRTCGGGVQLARRQCTNPTPANGGKYCEGVRVKYRSCNLEPCPSSASGKSFREEQCEAFNGYNHSTNRLTLAVAWVPKYSGVSPRDKCKLICRANGTGYFYVLAPKVVDGTLCSPDSTSVCVQGKCIKAGCDGNLGSKKRFDKCGVCGGDNKSCKKVTGLFTKPMHGYNFVVAIPAGASSIDIRQRGYKGLIGDDNYLALKNSQGKYLLNGHFVVSAVERDLVVKGSLLRYSGTGTAVESLQASRPILEPLTVEVLSVGKMTPPRVRYSFYLPKEPREDKSSHPKDPRGPSVLHNSVLSLSNQVEQPDDRPPARWVAGSWGPCSASCGSGLQKRAVDCRGSAGQRTVPACDAAHRPVETQACGEPCPTWELSAWSPCSKSCGRGFQRRSLKCVGHGGRLLARDQCNLHRKPQELDFCVLRPC", "output": "Metalloprotease which has proteolytic activity against the proteoglycan VCAN, cleaving it at the 'Glu-1428-|-1429-Ala' site. Cleaves VCAN in the pericellular matrix surrounding myoblasts, facilitating myoblast contact and fusion which is required for skeletal muscle development and regeneration."}]}
+{"id": "function_test_74", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MARCERLRGAALRDVLGRAQGVLFDCDGVLWNGERAVPGAPELLERLARAGKAALFVSNNSRRARPELALRFARLGFGGLRAEQLFSSALCAARLLRQRLPGPPDAPGAVFVLGGEGLRAELRAAGLRLAGDPSAGDGAAPRVRAVLVGYDEHFSFAKLREACAHLRDPECLLVATDRDPWHPLSDGSRTPGTGSLAAAVETASGRQALVVGKPSPYMFECITENFSIDPARTLMVGDRLETDILFGHRCGMTTVLTLTGVSRLEEAQAYLAAGQHDLVPHYYVESIADLTEGLED", "output": "Functions as a pyridoxal phosphate (PLP) phosphatase, which also catalyzes the dephosphorylation of pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), with order of substrate preference PLP > PNP > PMP and therefore plays a role in vitamin B6 metabolism . Also functions as a protein serine phosphatase that specifically dephosphorylates 'Ser-3' in proteins of the actin-depolymerizing factor (ADF)/cofilin family like CFL1 and DSTN. Thereby, regulates cofilin-dependent actin cytoskeleton reorganization, being required for normal progress through mitosis and normal cytokinesis. Does not dephosphorylate phosphothreonines in LIMK1. Does not dephosphorylate peptides containing phosphotyrosine ."}]}
+{"id": "function_test_75", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAAAGAAATHLEVARGKRAALFFAAVAIVLGLPLWWKTTETYRASLPYSQISGLNALQLRLMVPVTVVFTRESVPLDDQEKLPFTVVHEREIPLKYKMKIKCRFQKAYRRALDHEEEALSSGSVQEAEAMLDEPQEQAEGSLTVYVISEHSSLLPQDMMSYIGPKRTAVVRGIMHREAFNIIGRRIVQVAQAMSLTEDVLAAALADHLPEDKWSAEKRRPLKSSLGYEITFSLLNPDPKSHDVYWDIEGAVRRYVQPFLNALGAAGNFSVDSQILYYAMLGVNPRFDSASSSYYLDMHSLPHVINPVESRLGSSAASLYPVLNFLLYVPELAHSPLYIQDKDGAPVATNAFHSPRWGGIMVYNVDSKTYNASVLPVRVEVDMVRVMEVFLAQLRLLFGIAQPQLPPKCLLSGPTSEGLMTWELDRLLWARSVENLATATTTLTSLAQLLGKISNIVIKDDVASEVYKAVAAVQKSAEELASGHLASAFVASQEAVTSSELAFFDPSLLHLLYFPDDQKFAIYIPLFLPMAVPILLSLVKIFLETRKSWRKPEKTD", "output": "Component of the GPI transamidase complex. Essential for transfer of GPI to proteins, particularly for formation of carbonyl intermediates."}]}
+{"id": "function_test_76", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSEAYFRVESGALGPEENFLSLDDILMSHEKLPVRTETAMPRLGAFFLERSAGAETDNAVPQGSKLELPLWLAKGLFDNKRRILSVELPKIYQEGWRTVFSADPNVVDLHKMGPHFYGFGSQLLHFDSPENADISQSLLQTFIGRFRRIMDSSQNAYNEDTSALVARLDEMERGLFQTGQKGLNDFQCWEKGQASQITASNLVQNYKKRKFTDMED", "output": "Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks . GINS complex is a core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built ."}]}
+{"id": "function_test_77", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEPLASNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVDVESLVFGGEAELLRGFVAGQEHSYSHGGGAWL", "output": "Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation (By similarity)."}]}
+{"id": "function_test_78", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSSDEKGISPAHKTSTPTHRSASSSTSSQRDSRQSIHILERTASSSTEPSVSRQLLEPEPVPLSKEADSWEIIEGLKIGQTNVQKPDKHEGFMLKKRKWPLKGWHKRFFVLDNGMLKYSKAPLDIQKGKVHGSIDVGLSVMSIKKKARRIDLDTEEHIYHLKVKSQDWFDAWVSKLRHHRLYRQNEIVRSPRDASFHIFPSTSTAESSPAANVSVMDGKMQPNSFPWQSPLPCSNSLPATCTTGQSKVAAWLQDSEEMDRCAEDLAHCQSNLVELSKLLQNLEILQRTQSAPNFTDMQANCVDISKKDKRVTRRWRTKSVSKDTKIQLQVPFSATMSPVRLHSSNPNLCADIEFQTPPSHLTDPLESSTDYTKLQEEFCLIAQKVHSLLKSAFNSIAIEKEKLKQMVSEQDHSKGHSTQMARLRQSLSQALNQNAELRSRLNRIHSESIICDQVVSVNIIPSPDEAGEQIHVSLPLSQQVANESRLSMSESVSEFFDAQEVLLSASSSENEASDDESYISDVSDNISEDNTSVADNISRQILNGELTGGAFRNGRRACLPAPCPDTSNINLWNILRNNIGKDLSKVSMPVELNEPLNTLQHLCEEMEYSELLDKASETDDPYERMVLVAAFAVSGYCSTYFRAGSKPFNPVLGETYECIREDKGFRFFSEQVSHHPPISACHCESKNFVFWQDIRWKNKFWGKSMEILPVGTLNVMLPKYGDYYVWNKVTTCIHNILSGRRWIEHYGEVTIRNTKSSVCICKLTFVKVNYWNSNMNEVQGVVIDQEGKAVYRLFGKWHEGLYCGVAPSAKCIWRPGSMPTNYELYYGFTRFAIELNELDPVLKDLLPPTDARFRPDQRFLEEGNLEAAASEKQRVEELQRSRRRYMEENNLEHIPKFFKKVIDANQREAWVSNDTYWELRKDPGFSKVDSPVLW", "output": "Regulates cellular transport and efflux of cholesterol . Plays a role in phosphatidylinositol-4-phophate (PI4P) turnover at the neuronal membrane (By similarity). Binds via its PH domain PI4P, phosphatidylinositol-4,5-diphosphate, phosphatidylinositol-3,4,5-triphosphate, and phosphatidic acid (By similarity). Weakly binds 25-hydroxycholesterol ."}]}
+{"id": "function_test_79", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSAQAQMRALLDQLMGTARDGDETRQRVKFTDDRVCKSHLLDCCPHDILAGTRMDLGECTKIHDLALRADYEIASKERDLFFELDAMDHLESFIAECDRRTELAKKRLAETQEEISAEVSAKAEKVHELNEEIGKLLAKAEQLGAEGNVDESQKILMEVEKVRAKKKEAEEEYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSRTRDRRRSRSRDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKYKFSRERASREESWESGRSERGPPDWRLESSNGKMASRRSEEKEAGEI", "output": "May bind to RNA via its Arg/Ser-rich domain."}]}
+{"id": "function_test_80", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSVGRRRIKLLGILMMANVFIYFIMEVSKSSSQEKNGKGEVIIPKEKFWKISTPPEAYWNREQEKLNRQYNPILSMLTNQTGEAGRLSNISHLNYCEPDLRVTSVVTGFNNLPDRFKDFLLYLRCRNYSLLIDQPDKCAKKPFLLLAIKSLTPHFARRQAIRESWGQESNAGNQTVVRVFLLGQTPPEDNHPDLSDMLKFESEKHQDILMWNYRDTFFNLSLKEVLFLRWVSTSCPDTEFVFKGDDDVFVNTHHILNYLNSLSKTKAKDLFIGDVIHNAGPHRDKKLKYYIPEVVYSGLYPPYAGGGGFLYSGHLALRLYHITDQVHLYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIEEKNKNNICSYVDLMLVHSRKPQEMIDIWSQLQSAHLKC", "output": "Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains. Shows a marked preference for Gal(beta1-4)Glc(NAc)-based acceptors . Probably constitutes the main polylactosamine synthase."}]}
+{"id": "function_test_81", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAARPLSRMLRRLLRSSARSCSSGAPVTQPCPGESARAASEEVSRRRQFLREHAAPFSAFLTDSFGRQHSYLRISLTEKCNLRCQYCMPEEGVPLTPKANLLTTEEILTLARLFVKEGIDKIRLTGGEPLIRPDVVDIVAQLQRLEGLRTIGVTTNGINLARLLPQLQKAGLSAINISLDTLVPAKFEFIVRRKGFHKVMEGIHKAIELGYNPVKVNCVVMRGLNEDELLDFAALTEGLPLDVRFIEYMPFDGNKWNFKKMVSYKEMLDTVRQQWPELEKVPEEESSTAKAFKIPGFQGQISFITSMSEHFCGTCNRLRITADGNLKVCLFGNSEVSLRDHLRAGASEQELLRIIGAAVGRKKRQHAGMFSISQMKNRPMILIELFLMFPNSPPANPSIFSWDPLHVQGLRPRMSFSSQVATLWKGCRVPQTPPLAQQRLGSGSFQRHYTSRADSDANSKCLSPGSWASAAPSGPQLTSEQLTHVDSEGRAAMVDVGRKPDTERVAVASAVVLLGPVAFKLVQQNQLKKGDALVVAQLAGVQAAKVTSQLIPLCHHVALSHIQVQLELDSTRHAVKIQASCRARGPTGVEMEALTSAAVAALTLYDMCKAVSRDIVLEEIKLISKTGGQRGDFHRA", "output": "Isoform MOCS1A and isoform MOCS1B probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP). MOCS1A catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate and MOCS1B catalyzes the subsequent conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cPMP."}]}
+{"id": "function_test_82", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTRLLGYVDPLDPSFVAAVITITFNPLYWNVVARWEHKTRKLSRAFGSPYLACYSLSVTILLLNFLRSHCFTQAMLSQPRMESLDTPAAYSLGLALLGLGVVLVLSSFFALGFAGTFLGDYFGILKEARVTVFPFNILDNPMYWGSTANYLGWAIMHASPTGLLLTVLVALTYIVALLYEEPFTAEIYRQKASGSHKRS", "output": "Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure . Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step . Responsible for approximately 30% of hepatic PC with the CDP-choline pathway accounting for the other 70% (Probable).; "}]}
+{"id": "function_test_83", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAQHHLWILLLCLQTWPEAAGKDSEIFTVNGILGESVTFPVNIQEPRQVKIIAWTSKTSVAYVTPGDSETAPVVTVTHRNYYERIHALGPNYNLVISDLRMEDAGDYKADINTQADPYTTTKRYNLQIYRRLGKPKITQSLMASVNSTCNVTLTCSVEKEEKNVTYNWSPLGEEGNVLQIFQTPEDQELTYTCTAQNPVSNNSDSISARQLCADIAMGFRTHHTGLLSVLAMFFLLVLILSSVFLFRLFKRRQGRIFPEGSCLNTFTKNPYAASKKTIYTYIMASRNTQPAESRIYDEILQSKVLPSKEEPVNTVYSEVQFADKMGKASTQDSKPPGTSSYEIVI", "output": "Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Can mediate natural killer (NK) cell cytotoxicity dependent on SH2D1A and SH2D1B (By similarity). Increases proliferative responses of activated T-cells and SH2D1A/SAP does not seem be required for this process. Homophilic interactions enhance interferon gamma/IFNG secretion in lymphocytes and induce platelet stimulation via a SH2D1A-dependent pathway. May serve as a marker for hematopoietic progenitor cells  Required for a prolonged T-cell:B-cell contact, optimal T follicular helper function, and germinal center formation. In germinal centers involved in maintaining B-cell tolerance and in preventing autoimmunity (By similarity). In mast cells negatively regulates high affinity immunoglobulin epsilon receptor signaling; independent of SH2D1A and SH2D1B but implicating FES and PTPN6/SHP-1 . In macrophages enhances LPS-induced MAPK phosphorylation and NF-kappaB activation and modulates LPS-induced cytokine secretion; involving ITSM 2 (By similarity). Positively regulates macroautophagy in primary dendritic cells via stabilization of IRF8; inhibits TRIM21-mediated proteasomal degradation of IRF8 ."}]}
+{"id": "function_test_84", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAECGRGGAAGGALPTSPGPALGAKGALKAGVGEGGGGGGRLGHGRARYDSGGVSNGDCSLGVSGDEARASPTRGPRGVALAPTPSAVVCTLPRESKPGGLPRRSSIIKDGTKQKRERKKTVSFSSMPTEKKISSASDCINSMVEGSELKKVRSNSRIYHRYFLLDADMQSLRWEPSKKDSEKAKIDIKSIKEVRTGKNTDIFRSNGISDQISEDCAFSVIYGENYESLDLVANSADVANIWVTGLRYLISYGKHTLDMLESSQDNMRTSWVSQMFSEIDVDNLGHITLCNAVQCIRNLNPGLKTSKIELKFKELHKSKDKAGTEVTKEEFIEVFHELCTRPEIYFLLVQFSSNKEFLDTKDLMMFLEAEQGVAHINEEISLEIIHKYEPSKEGQEKGWLSIDGFTNYLMSPDCYIFDPEHKKVCQDMKQPLSHYFINSSHNTYLIEDQFRGPSDITGYIRALKMGCRSVELDVWDGPDNEPVIYTGHTMTSQIVFRSVIDIINKYAFFASEYPLILCLENHCSIKQQKVMVQHMKKLLGDKLYTTSPNVEESYLPSPDVLKGKILIKAKKLSSNCSGVEGDVTDEDEGAEMSQRMGKENMEQPNNVPVKRFQLCKELSELVSICKSVQFKEFQVSFQVQKYWEVCSFNEVLASKYANENPGDFVNYNKRFLARVFPSPMRIDSSNMNPQDFWKCGCQIVAMNFQTPGLMMDLNIGWFRQNGNCGYVLRPAIMREEVSFFSANTKDSVPGVSPQLLHIKIISGQNFPKPKGSGAKGDVVDPYVYVEIHGIPADCAEQRTKTVHQNGDAPIFDESFEFQINLPELAMVRFVVLDDDYIGDEFIGQYTIPFECLQTGYRHVPLQSLTGEVLAHASLFVHVAITNRRGGGKPHKRGLSVRKGKKSREYASLRTLWIKTVDEVFKNAQPPIRDATDLRENMQNAVVSFKELCGLSSVANLMQCMLAVSPRFLGPDNTPLVVLNLSEQYPTMELQGIVPEVLKKIVTTYDMMIQSLKALIENADAVYEKIVHCQKAAMEFHEHLHSIGTKEGLKERKLQKAVESFTWNITILKGQADLLKYAKNETLENLKQIHFAAVSCGLNKPGTENADVQKPRRSLEVIPEKANDETGE", "output": "May play an role in the regulation of Ins(1,4,5)P3 around the endoplasmic reticulum."}]}
+{"id": "function_test_85", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSVDLIKTYKHINEVYYAKKKRRAQQAPPQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERLPGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLRMLEYEPAARISPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSSDNRTYRYSNRYCGGPGPPITDCEMNSPQVPPSQPLRPWAGGDVPHKTHQAPASASSLPGTGAQLPPQPRYLGRPPSPTSPPPPELMDVSLVGGPADCSPPHPAPAPQHPAASALRTRMTGGRPPLPPPDDPATLGPHLGLRGVPQSTAASS", "output": "Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Plays an essential role in ribosomal DNA (rDNA) double-strand break repair and rDNA copy number maintenance . During DNA damage, mediates transcription silencing in part via phosphorylating and enforcing DSB accumulation of the histone methyltransferase EHMT2 . Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase catalytic subunit 1 (G6PC1)."}]}
+{"id": "function_test_86", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNHSERFVFIAEWYDPNASLLRRYELLFYPGDGSVEMHDVKNHRTFLKRTKYDNLHLEDLFIGNKVNVFSRQLVLIDYGDQYTARQLGSRKEKTLALIKPDAISKAGEIIEIINKAGFTITKLKMMMLSRKEALDFHVDHQSRPFFNELIQFITTGPIIAMEILRDDAICEWKRLLGPANSGVARTDASESIRALFGTDGIRNAAHGPDSFASAAREMELFFPSSGGCGPANTAKFTNCTCCIVKPHAVSEGLLGKILMAIRDAGFEISAMQMFNMDRVNVEEFYEVYKGVVTEYHDMVTEMYSGPCVAMEIQQNNATKTFREFCGPADPEIARHLRPGTLRAIFGKTKIQNAVHCTDLPEDGLLEVQYFFKILDN", "output": "Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (By similarity)."}]}
+{"id": "function_test_87", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDFPGHFEQIFQQLNYQRLHGQLCDCVIVVGNRHFKAHRSVLAACSTHFRALFSVAEGDQTMNMIQLDSEVVTAEAFAALIDMMYTSTLMLGESNVMDVLLAASHLHLNSVVKACKHYLTTRTLPMSPPSERVQEQSARMQRSFMLQQLGLSIVSSALNSSQNGEEQPAPMSSSMRSNLDQRTPFPMRRLHKRKQSAEERARQRLRPSIDESAISDVTPENGPSGVHSREEFFSPDSLKIVDNPKADGMTDNQEDSAIMFDQSFGTQEDAQVPSQSDNSAGNMAQLSMASRATQVETSFDQEAAPEKSSFQCENPEVGLGEKEHMRVVVKSEPLSSPEPQDEVSDVTSQAEGSESVEVEGVVVSAEKIDLSPESSDRSFSDPQSSTDRVGDIHILEVTNNLEHKSTFSISNFLNKSRGNNFTANQNNDDNIPNTTSDCRLESEAPYLLSPEAGPAGGPSSAPGSHVENPFSEPADSHFVRPMQEVMGLPCVQTSGYQGGEQFGMDFSRSGLGLHSSFSRVMIGSPRGGASNFPYYRRIAPKMPVVTSVRSSQIPENSTSSQLMMNGATSSFENGHPSQPGPPQLTRASADVLSKCKKALSEHNVLVVEGARKYACKICCKTFLTLTDCKKHIRVHTGEKPYACLKCGKRFSQSSHLYKHSKTTCLRWQSSNLPSTLL", "output": "May be involved in transcriptional regulation."}]}
+{"id": "function_test_88", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNMTQARVLVAAVVGLVAVLLYASIHKIEEGHLAVYYRGGALLTSPSGPGYHIMLPFITTFRSVQTTLQTDEVKNVPCGTSGGVMIYIDRIEVVNMLAPYAVFDIVRNYTADYDKTLIFNKIHHELNQFCSAHTLQEVYIELFDQIDENLKQALQKDLNLMAPGLTIQAVRVTKPKIPEAIRRNFELMEAEKTKLLIAAQKQKVVEKEAETERKKAVIEAEKIAQVAKIRFQQKVMEKETEKRISEIEDAAFLAREKAKADAEYYAAHKYATSNKHKLTPEYLELKKYQAIASNSKIYFGSNIPNMFVDSSCALKYSDIRTGRESSLPSKEALEPSGENVIQNKESTG", "output": "Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex .; "}]}
+{"id": "function_test_89", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAATELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYKKHRRTMIISPERLDPFADGGKTPDPKMNARTYMDVMREQHLTKEEREIRQQLAEKAKAGELKVVNGAAASQPPSKRKRRWDQTADQTPGATPKKLSSWDQAETPGHTPSLRWDETPGRAKGSETPGATPGSKIWDPTPSHTPAGAATPGRGDTPGHATPGHGGATSSARKNRWDETPKTERDTPGHGSGWAETPRTDRGGDSIGETPTPGASKRKSRWDETPASQMGGSTPVLTPGKTPIGTPAMNMATPTPGHIMSMTPEQLQAWRWEREIDERNRPLSDEELDAMFPEGYKVLPPPAGYVPIRTPARKLTATPTPLGGMTGFHMQTEDRTMKSVNDQPSGNLPFLKPDDIQYFDKLLVDVDESTLSPEEQKERKIMKLLLKIKNGTPPMRKAALRQITDKAREFGAGPLFNQILPLLMSPTLEDQERHLLVKVIDRILYKLDDLVRPYVHKILVVIEPLLIDEDYYARVEGREIISNLAKAAGLATMISTMRPDIDNMDEYVRNTTARAFAVVASALGIPSLLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGCAILPHLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAATPYGIESFDSVLKPLWKGIRQHRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFQSPDEEMKKIVLKVVKQCCGTDGVEANYIKTEILPPFFKHFWQHRMALDRRNYRQLVDTTVELANKVGAAEIISRIVDDLKDEAEQYRKMVMETIEKIMGNLGAADIDHKLEEQLIDGILYAFQEQTTEDSVMLNGFGTVVNALGKRVKPYLPQICGTVLWRLNNKSAKVRQQAADLISRTAVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMHKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIADRGAEYVSAREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPALMNEYRVPELNVQNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGVYGFGCEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMLQYCLQGLFHPARKVRDVYWKIYNSIYIGSQDALIAHYPRIYNDDKNTYIRYELDYIL", "output": "Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex . SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA . Together with other U2 snRNP complex components may also play a role in the selective processing of microRNAs (miRNAs) from the long primary miRNA transcript, pri-miR-17-92 (By similarity). May also be involved in the assembly of the 'E' complex . As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs  (Probable)."}]}
+{"id": "function_test_90", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTMESGAENQQSGDAAVTEAENQQMTVQAQPQIATLAQVSMPAAHATSSAPTVTLVQLPNGQTVQVHGVIQAAQPSVIQSPQVQTVQISTIAESEDSQESVDSVTDSQKRREILSRRPSYRKILNDLSSDAPGVPRIEEEKSEEETSAPAITTVTVPTPIYQTSSGQYIAITQGGAIQLANNGTDGVQGLQTLTMTNAAATQPGTTILQYAQTTDGQQILVPSNQVVVQAASGDVQTYQIRTAPTSTIAPGVVMASSPALPTQPAEEAARKREVRLMKNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKALKDLYCHKSD", "output": "Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-119 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells."}]}
+{"id": "function_test_91", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPEIRLRHVVSCSSQDSTHCAENLLKADTYRKWRAAKAGEKTISVVLQLEKEEQIHSVDIGNDGSAFVEVLVGSSAGGAGEQDYEVLLVTSSFMSPSESRSGSNPNRVRMFGPDKLVRAAAEKRWDRVKIVCSQPYSKDSPFGLSFVRFHSPPDKDEAEAPSQKVTVTKLGQFRVKEEDESANSLRPGALFFSRINKTSPVTASDPAGPSYAAATLQASSAASSASPVSRAIGSTSKPQESPKGKRKLDLNQEEKKTPSKPPAQLSPSVPKRPKLPAPTRTPATAPVPARAQGAVTGKPRGEGTEPRRPRAGPEELGKILQGVVVVLSGFQNPFRSELRDKALELGAKYRPDWTRDSTHLICAFANTPKYSQVLGLGGRIVRKEWVLDCHRMRRRLPSQRYLMAGPGSSSEEDEASHSGGSGDEAPKLPQKQPQTKTKPTQAAGPSSPQKPPTPEETKAASPVLQEDIDIEGVQSEGQDNGAEDSGDTEDELRRVAEQKEHRLPPGQEENGEDPYAGSTDENTDSEEHQEPPDLPVPELPDFFQGKHFFLYGEFPGDERRKLIRYVTAFNGELEDYMSDRVQFVITAQEWDPSFEEALMDNPSLAFVRPRWIYSCNEKQKLLPHQLYGVVPQA", "output": "Scaffold protein involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes . Negatively regulates ADP-ribosyltransferase activity of PARP1 during base-excision repair in order to prevent excessive PARP1 activity . Recognizes and binds poly-ADP-ribose chains: specifically binds auto-poly-ADP-ribosylated PARP1, limiting its activity ."}]}
+{"id": "function_test_92", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA", "output": "AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis . This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates . Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported . AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface (By similarity). Phosphorylation of PTPN1 at 'Ser-50' negatively modulates its phosphatase activity preventing dephosphorylation of the insulin receptor and the attenuation of insulin signaling (By similarity). Phosphorylation of TBC1D4 triggers the binding of this effector to inhibitory 14-3-3 proteins, which is required for insulin-stimulated glucose transport . AKT regulates also the storage of glucose in the form of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at 'Ser-9', resulting in inhibition of its kinase activity (By similarity). Phosphorylation of GSK3 isoforms by AKT is also thought to be one mechanism by which cell proliferation is driven (By similarity). AKT regulates also cell survival via the phosphorylation of MAP3K5 (apoptosis signal-related kinase) . Phosphorylation of 'Ser-83' decreases MAP3K5 kinase activity stimulated by oxidative stress and thereby prevents apoptosis . AKT mediates insulin-stimulated protein synthesis by phosphorylating TSC2 at 'Ser-939' and 'Thr-1462', thereby activating the TORC1 signaling pathway, and leading to both phosphorylation of 4E-BP1 and in activation of RPS6KB1 . Also regulates the TORC1 signaling pathway by catalyzing phosphorylation of CASTOR1 . AKT is involved in the phosphorylation of members of the FOXO factors (Forkhead family of transcription factors), leading to binding of 14-3-3 proteins and cytoplasmic localization . In particular, FOXO1 is phosphorylated at 'Thr-24', 'Ser-256' and 'Ser-319' . FOXO3 and FOXO4 are phosphorylated on equivalent sites . AKT has an important role in the regulation of NF-kappa-B-dependent gene transcription and positively regulates the activity of CREB1 (cyclic AMP (cAMP)-response element binding protein) . The phosphorylation of CREB1 induces the binding of accessory proteins that are necessary for the transcription of pro-survival genes such as BCL2 and MCL1 . AKT phosphorylates 'Ser-454' on ATP citrate lyase (ACLY), thereby potentially regulating ACLY activity and fatty acid synthesis (By similarity). Activates the 3B isoform of cyclic nucleotide phosphodiesterase (PDE3B) via phosphorylation of 'Ser-273', resulting in reduced cyclic AMP levels and inhibition of lipolysis (By similarity). Phosphorylates PIKFYVE on 'Ser-318', which results in increased PI(3)P-5 activity (By similarity). The Rho GTPase-activating protein DLC1 is another substrate and its phosphorylation is implicated in the regulation cell proliferation and cell growth. AKT plays a role as key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation (By similarity). Signals downstream of phosphatidylinositol 3-kinase (PI(3)K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I) . AKT mediates the antiapoptotic effects of IGF-I (By similarity). Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly . May be involved in the regulation of the placental development (By similarity). Phosphorylates STK4/MST1 at 'Thr-120' and 'Thr-387' leading to inhibition of its: kinase activity, nuclear translocation, autophosphorylation and ability to phosphorylate FOXO3 . Phosphorylates STK3/MST2 at 'Thr-117' and 'Thr-384' leading to inhibition of its: cleavage, kinase activity, autophosphorylation at Thr-180, binding to RASSF1 and nuclear translocation . Phosphorylates SRPK2 and enhances its kinase activity towards SRSF2 and ACIN1 and promotes its nuclear translocation . Phosphorylates RAF1 at 'Ser-259' and negatively regulates its activity . Phosphorylation of BAD stimulates its pro-apoptotic activity . Phosphorylates KAT6A at 'Thr-369' and this phosphorylation inhibits the interaction of KAT6A with PML and negatively regulates its acetylation activity towards p53/TP53 . Phosphorylates palladin (PALLD), modulating cytoskeletal organization and cell motility . Phosphorylates prohibitin (PHB), playing an important role in cell metabolism and proliferation . Phosphorylates CDKN1A, for which phosphorylation at 'Thr-145' induces its release from CDK2 and cytoplasmic relocalization . These recent findings indicate that the AKT1 isoform has a more specific role in cell motility and proliferation . Phosphorylates CLK2 thereby controlling cell survival to ionizing radiation . Phosphorylates PCK1 at 'Ser-90', reducing the binding affinity of PCK1 to oxaloacetate and changing PCK1 into an atypical protein kinase activity using GTP as donor . Also acts as an activator of TMEM175 potassium channel activity in response to growth factors: forms the lysoK(GF) complex together with TMEM175 and acts by promoting TMEM175 channel activation, independently of its protein kinase activity . Acts as an inhibitor of tRNA methylation by mediating phosphorylation of the N-terminus of METTL1, thereby inhibiting METTL1 methyltransferase activity ."}]}
+{"id": "function_test_93", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDSKHQCVKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSDSFASHPNYPYSDEY", "output": "Cytosolic aldo-keto reductase that catalyzes the NADH and NADPH-dependent reduction of ketosteroids to hydroxysteroids. Acts as a NAD(P)(H)-dependent 3-, 17- and 20-ketosteroid reductase on the steroid nucleus and side chain and regulates the metabolism of androgens, estrogens and progesterone . Displays the ability to catalyze both oxidation and reduction in vitro, but most probably acts as a reductase in vivo since the oxidase activity measured in vitro is inhibited by physiological concentration of NADPH . Acts preferentially as a 17-ketosteroid reductase and has the highest catalytic efficiency of the AKR1C enzyme for the reduction of delta4-androstenedione to form testosterone . Reduces prostaglandin (PG) D2 to 11beta-prostaglandin F2, progesterone to 20alpha-hydroxyprogesterone and estrone to 17beta-estradiol . Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol) . Also displays retinaldehyde reductase activity toward 9-cis-retinal ."}]}
+{"id": "function_test_94", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MARARPPPPPSPPPGLLPLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAGRVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHGAGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEGIASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQYIAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAGEFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQTLPVQV", "output": "Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Generally has an overlapping and redundant function with EPHB2. Like EPHB2, functions in axon guidance during development regulating for instance the neurons forming the corpus callosum and the anterior commissure, 2 major interhemispheric connections between the temporal lobes of the cerebral cortex. In addition to its role in axon guidance also plays an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and the formation of excitatory synapses. Controls other aspects of development through regulation of cell migration and positioning. This includes angiogenesis, palate development and thymic epithelium development for instance. Forward and reverse signaling through the EFNB2/EPHB3 complex also regulate migration and adhesion of cells that tubularize the urethra and septate the cloaca. Finally, plays an important role in intestinal epithelium differentiation segregating progenitor from differentiated cells in the crypt."}]}
+{"id": "function_test_95", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGSAFERVVRRVVQELDHGGEFIPVTSLQSSTGFQPYCLVVRKPSSSWFWKPRYKCVNLSIKDILEPDAAEPDVQRGRSFHFYDAMDGQIQGSVELAAPGQAKIAGGAAVSDSSSTSMNVYSLSVDPNTWQTLLHERHLRQPEHKVLQQLRSRGDNVYVVTEVLQTQKEVEVTRTHKREGSGRFSLPGATCLQGEGQGHLSQKKTVTIPSGSTLAFRVAQLVIDSDLDVLLFPDKKQRTFQPPATGHKRSTSEGAWPQLPSGLSMMRCLHNFLTDGVPAEGAFTEDFQGLRAEVETISKELELLDRELCQLLLEGLEGVLRDQLALRALEEALEQGQSLGPVEPLDGPAGAVLECLVLSSGMLVPELAIPVVYLLGALTMLSETQHKLLAEALESQTLLGPLELVGSLLEQSAPWQERSTMSLPPGLLGNSWGEGAPAWVLLDECGLELGEDTPHVCWEPQAQGRMCALYASLALLSGLSQEPH", "output": "[Gasdermin-D]: Precursor of a pore-forming protein that plays a key role in host defense against pathogen infection and danger signals . This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-D, N-terminal) binds to membranes and forms pores, triggering pyroptosis .; "}]}
+{"id": "function_test_96", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGLLLLVLILTPSLAAYRHPDFPLLEKAQQLLQSTGSPYSTNCWLCTSSSTETPGTAYPASPREWTSIEAELHISYRWDPNLKGLMRPANSLLSTVKQDFPDIRQKPPIFGPIFTNINLMGIAPICVMAKRKNGTNVGTLPSTVCNVTFTVDSNQQTYQTYTHNQFRHQPRFPKPPNITFPQGTLLDKSSRFCQGRPSSCSTRNFWFRPADYNQCLQISNLSSTAEWVLLDQTRNSLFWENKTKGANQSQTPCVQVLAGMTIATSYLGISAVSEFFGTSLTPLFHFHISTCLKTQGAFYICGQSIHQCLPSNWTGTCTIGYVTPDIFIAPGNLSLPIPIYGNSPLPRVRRAIHFIPLLAGLGILAGTGTGIAGITKASLTYSQLSKEIANNIDTMAKALTTMQEQIDSLAAVVLQNRRGLDMLTAAQGGICLALDEKCCFWVNQSGKVQDNIRQLLNQASSLRERATQGWLNWEGTWKWFSWVLPLTGPLVSLLLLLLFGPCLLNLITQFVSSRLQAIKLQTNLSAGRHPRNIQESPF", "output": "This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process .; "}]}
+{"id": "function_test_97", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MQRGKPCRALPTLKCQTFCQRHGLMFEVVDLRWGIRNIEATDHLTTELCLEEVDRCWKTSIGPAFVALIGDQYGPCLIPSRIDEKEWEVLRDHLTARPSDLELVARYFQRDENAFPPTYVLQAPGTGEACEPEEATLTSVLRSGAQEARRLGLITQEQWQHYHRSVIEWEIERSLLSSEDREQGATVFLREIQDLHKHILEDCALRMVDRLADGCLDADAQNLLSSLKSHITDMHPGVLKTHRLPWSRDLVNPKNKTHACYLKELGEQFVVRANHQVLTRLRELDTAGQELAWLYQEIRHHLWQSSEVIQTFCGRQELLARLGQQLRHDDSKQHTPLVLFGPPGIGKTALMCKLAEQMPRLLGHKTVTVLRLLGTSQMSSDARGLLKSICFQVCLAYGLPLPPAQVLDAHTRVVQFFHTLLHTVSCRNFESLVLLLDAMDDLDSVRHARRVPWLPLNCPPRVHLILSACSGALGVLDTLQRVLLDPEAYWEVKPLSGNQGQQMIQLLLAAARRTLSPVHTDLLWASLPECGNPGRLRLAFEEARKWASFTVPVPLATTAEEATHQLCTRLEQTHGQLLVAHVLGYIVSSRHGLSEAELKDVLSLDDEVLQDVYRDWTPPSKELLRFPPLLWVRLRRDLGYYLARRPVDGFTLLAIAHRQLVEVVRERYLSGSERAKRHGVLADFFSGTWSQGTKKLITLPLVGKPLNLDRKVAPQPLWFSHTVANLRKLKELPYHLLHSGRLEELKQEVLGSMSWISCRGISGGIEDLLDDFDLCAPHLDSPEVGLVREALQLCRPAVELRGMERSLLYTELLARLHFFATSHPALVGQLCQQAQSWFQLCAHPVLVPLGGFLQPPGGPLRATLSGCHKGITAMAWGVEEKLLVIGTQDGIMAVWDMEEQHVIHMLTGHTGEVRCVKIFAKGTLANSASKDYTLHLWNLLSGQEKFTIWDGGSKNPAEPQIWNLHVDEAHKVVYSASGSKINAWNLETAEPVFHILGDASDPWMCMAVLASQATLLTVSRDGVVSLWSSATGKLQGKQHMSSIKEETPTCAVSVQKQGKLVTGFSNGSISLVSSKGDRLLEKLPDAVRFLVVSEDESLLAAGFGRSVRIFLADSRGFRRFMAMDLEHEDMVETAVFGTENNLIITGSLDALIQVWSLSEQGTLLDILEGVGAPVSLLARGGALVASASPQSSSFKVWDLSDAHRSRVPAPFLDRTGLTAVSHNGSYVYFPKIGDKNKVTIWDLAEGEEQDSLDTSSEIRCLEVAEQRKLLFTGLVSGVVLVFPLNSRQDVICIPPPEARKAINCMSLSKCEDRLAIAYDNIVLVLDITSGDPCPVIDGPRYTFYTQLPETLSSVAILTDYRVVYSMTNGDLFLYECATSKAFPLETHRSRVACVEVSHKEQLVVSGSEDALLCLWDLQARKWKFEMSYTSSYCRGVQCACFSKDDKYVYVGLKDRSILVWSVLDGTLLTVQFVHAVVNRIIPTTSGFIAPTRHGYLIRENFQCLSAKASPQDPLKNFKKAMWMVKSRQREELVAAAGAPQDLESESAQGNETKSNKCSQVCLIV", "output": "May play a role in the control of androgen receptor (AR) protein steady-state levels."}]}
+{"id": "function_test_98", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAVSTGVKVPRNFRLLEELEEGQKGVGDGTVSWGLEDDEDMTLTRWTGMIIGPPRTNYENRIYSLKVECGPKYPEAPPSVRFVTKINMNGINNSSGMVDARSIPVLAKWQNSYSIKVVLQELRRLMMSKENMKLPQPPEGQTYNN", "output": "Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage."}]}
+{"id": "function_test_99", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSFGSEHYLCSSSSYRKVFGDGSRLSARLSGAGGAGGFRSQSLSRSNVASSAACSSASSLGLGLAYRRPPASDGLDLSQAAARTNEYKIIRTNEKEQLQGLNDRFAVFIEKVHQLETQNRALEAELAALRQRHAEPSRVGELFQRELRDLRAQLEEASSARSQALLERDGLAEEVQRLRARCEEESRGREGAERALKAQQRDVDGATLARLDLEKKVESLLDELAFVRQVHDEEVAELLATLQASSQAAAEVDVTVAKPDLTSALREIRAQYESLAAKNLQSAEEWYKSKFANLNEQAARSTEAIRASREEIHEYRRQLQARTIEIEGLRGANESLERQILELEERHSAEVAGYQDSIGQLENDLRNTKSEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTSGLSISGLNPLPNPSYLLPPRILSATTSKVSSTGLSLKKEEEEEEASKVASKKTSQIGESFEEILEETVISTKKTEKSNIEETTISSQKI", "output": "Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NEFL to form the filamentous backbone to which NEFM and NEFH attach to form the cross-bridges. May also cooperate with the neuronal intermediate filament protein PRPH to form filamentous networks (By similarity)."}]}
+{"id": "function_test_100", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKAARFVLRSAGSLNGAGLVPREVEHFSRYSPSPLSMKQLLDFGSENACERTSFAFLRQELPVRLANILKEIDILPTQLVNTSSVQLVKSWYIQSLMDLVEFHEKSPDDQKALSDFVDTLIKVRNRHHNVVPTMAQGIIEYKDACTVDPVTNQNLQYFLDRFYMNRISTRMLMNQHILIFSDSQTGNPSHIGSIDPNCDVVAVVQDAFECSRMLCDQYYLSSPELKLTQVNGKFPDQPIHIVYVPSHLHHMLFELFKNAMRATVEHQENQPSLTPIEVIVVLGKEDLTIKISDRGGGVPLRIIDRLFSYTYSTAPTPVMDNSRNAPLAGFGYGLPISRLYAKYFQGDLNLYSLSGYGTDAIIYLKALSSESIEKLPVFNKSAFKHYQMSSEADDWCIPSREPKNLAKEVAM", "output": "Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Inhibition of pyruvate dehydrogenase decreases glucose utilization and increases fat metabolism in response to prolonged fasting and starvation. Plays an important role in maintaining normal blood glucose levels under starvation, and is involved in the insulin signaling cascade. Via its regulation of pyruvate dehydrogenase activity, plays an important role in maintaining normal blood pH and in preventing the accumulation of ketone bodies under starvation. In the fed state, mediates cellular responses to glucose levels and to a high-fat diet. Regulates both fatty acid oxidation and de novo fatty acid biosynthesis. Plays a role in the generation of reactive oxygen species. Protects detached epithelial cells against anoikis. Plays a role in cell proliferation via its role in regulating carbohydrate and fatty acid metabolism."}]}
+{"id": "function_test_101", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAFSGCQAPYLSPAVPFSGTIQGGLQDGFQITVNGAVLSCSGTRFAVDFQTGFSGNDIAFHFNPRFEDGGYVVCNTRQKGTWGPEERKMHMPFQKGMPFDLCFLVQSSDFKVMVNGSLFVQYFHRVPFHRVDTISVNGSVQLSYISFQNPRAVPVQPAFSTVPFSQPVCFPPRPRGRRQKPPSVRPANPAPITQTVIHTVQSASGQMFSQTPAIPPMMYPHPAYPMPFITTIPGGLYPSKSIILSGTVLPSAQRFHINLCSGSHIAFHMNPRFDENAVVRNTQINNSWGSEERSLPRKMPFVRGQSFSVWILCEAHCLKVAVDGQHVFEYYHRLRNLPTINKLEVGGDIQLTHVQT", "output": "Binds galactosides."}]}
+{"id": "function_test_102", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAAAPRAGRRRGQPLLALLLLLLAPLPPGAPPGADAYFPEERWSPESPLQAPRVLIALLARNAAHALPTTLGALERLRHPRERTALWVATDHNMDNTSTVLREWLVAVKSLYHSVEWRPAEEPRSYPDEEGPKHWSDSRYEHVMKLRQAALKSARDMWADYILFVDADNLILNPDTLSLLIAENKTVVAPMLDSRAAYSNFWCGMTSQGYYKRTPAYIPIRKRDRRGCFAVPMVHSTFLIDLRKAASRNLAFYPPHPDYTWSFDDIIVFAFSCKQAEVQMYVCNKEEYGFLPVPLRAHSTLQDEAESFMHVQLEVMVKHPPAEPSRFISAPTKTPDKMGFDEVFMINLRRRQDRRERMLRALQAQEIECRLVEAVDGKAMNTSQVEALGIQMLPGYRDPYHGRPLTKGELGCFLSHYNIWKEVVDRGLQKSLVFEDDLRFEIFFKRRLMNLMRDVEREGLDWDLIYVGRKRMQVEHPEKAVPRVRNLVEADYSYWTLAYVISLQGARKLLAAEPLSKMLPVDEFLPVMFDKHPVSEYKAHFSLRNLHAFSVEPLLIYPTHYTGDDGYVSDTETSVVWNNEHVKTDWDRAKSQKMREQQALSREAKNSDVLQSPLDSAARDEL", "output": "Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of type I collagen . By acting on collagen glycosylation, facilitates the formation of collagen triple helix . Also involved in the biosynthesis of collagen type IV ."}]}
+{"id": "function_test_103", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAGAAAESGRELWTFAGSRDPSAPRLAYGYGPGSLRELRAREFSRLAGTVYLDHAGATLFSQSQLESFTSDLMENTYGNPHSQNISSKLTHDTVEQVRYRILAHFHTTAEDYTVIFTAGSTAALKLVAEAFPWVSQGPESSGSRFCYLTDSHTSVVGMRNVTMAINVISTPVRPEDLWSAEERSASASNPDCQLPHLFCYPAQSNFSGVRYPLSWIEEVKSGRLHPVSTPGKWFVLLDAASYVSTSPLDLSAHQADFVPISFYKIFGFPTGLGALLVHNRAAPLLRKTYFGGGTASAYLAGEDFYIPRQSVAQRFEDGTISFLDVIALKHGFDTLERLTGGMENIKQHTFTLAQYTYVALSSLQYPNGAPVVRIYSDSEFSSPEVQGPIINFNVLDDKGNIIGYSQVDKMASLYNIHLRTGCFCNTGACQRHLGISNEMVRKHFQAGHVCGDNMDLIDGQPTGSVRISFGYMSTLDDVQAFLRFIIDTRLHSSGDWPVPQAHADTGETGAPSADSQADVIPAVMGRRSLSPQEDALTGSRVWNNSSTVNAVPVAPPVCDVARTQPTPSEKAAGVLEGALGPHVVTNLYLYPIKSCAAFEVTRWPVGNQGLLYDRSWMVVNHNGVCLSQKQEPRLCLIQPFIDLRQRIMVIKAKGMEPIEVPLEENSERTQIRQSRVCADRVSTYDCGEKISSWLSTFFGRPCHLIKQSSNSQRNAKKKHGKDQLPGTMATLSLVNEAQYLLINTSSILELHRQLNTSDENGKEELFSLKDLSLRFRANIIINGKRAFEEEKWDEISIGSLRFQVLGPCHRCQMICIDQQTGQRNQHVFQKLSESRETKVNFGMYLMHASLDLSSPCFLSVGSQVLPVLKENVEGHDLPASEKHQDVTS", "output": "Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. In vitro, the C-terminal domain is able to reduce N-hydroxylated prodrugs, such as benzamidoxime."}]}
+{"id": "function_test_104", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPVMKGLLAPQNTFLDTIATRFDGTHSNFILANAQVAKGFPIVYCSDGFCELAGFARTEVMQKSCSCKFLFGVETNEQLMLQIEKSLEEKTEFKGEIMFYKKNGSPFWCLLDIVPIKNEKGDVVLFLASFKDITDTKVKITPEDKKEDKVKGRSRAGTHFDSARRRSRAVLYHISGHLQRREKNKLKINNNVFVDKPAFPEYKVSDAKKSKFILLHFSTFKAGWDWLILLATFYVAVTVPYNVCFIGNDDLSTTRSTTVSDIAVEILFIIDIILNFRTTYVSKSGQVIFEARSICIHYVTTWFIIDLIAALPFDLLYAFNVTVVSLVHLLKTVRLLRLLRLLQKLDRYSQHSTIVLTLLMSMFALLAHWMACIWYVIGKMEREDNSLLKWEVGWLHELGKRLESPYYGNNTLGGPSIRSAYIAALYFTLSSLTSVGFGNVSANTDAEKIFSICTMLIGALMHALVFGNVTAIIQRMYSRWSLYHTRTKDLKDFIRVHHLPQQLKQRMLEYFQTTWSVNNGIDSNELLKDFPDELRSDITMHLNKEILQLSLFECASRGCLRSLSLHIKTSFCAPGEYLLRQGDALQAIYFVCSGSMEVLKDSMVLAILGKGDLIGANLSIKDQVIKTNADVKALTYCDLQCIILKGLFEVLDLYPEYAHKFVEDIQHDLTYNLREGHESDVISRLSNKSMVSQSEPKGNGNINKRLPSIVEDEEEEEEGEEEEAVSLSPICTRGSSSRNKKVGSNKAYLGLSLKQLASGTVPFHSPIRVSRSNSPKTKQEIDPPNHNKRKEKNLKLQLSTLNNAGPPDLSPRIVDGIEDGNSSEESQTFDFGSERIRSEPRISPPLGDPEIGAAVLFIKAEETKQQINKLNSEVTTLTQEVSQLGKDMRNVIQLLENVLSPQQPSRFCSLHSTSVCPSRESLQTRTSWSAHQPCLHLQTGGAAYTQAQLCSSNITSDIWSVDPSSVGSSPQRTGAHEQNPADSELYHSPSLDYSPSHYQVVQEGHLQFLRCISPHSDSTLTPLQSISATLSSSVCSSSETSLHLVLPSRSEEGSFSQGTVSSFSLENLPGSWNQEGMASASTKPLENLPLEVVTSTAEVKDNKAINV", "output": "Pore-forming (alpha) subunit of voltage-gated potassium channel. Elicits a slowly activating, outward rectifying current. Channel properties may be modulated by cAMP and subunit assembly."}]}
+{"id": "function_test_105", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGDQQLYKTNHVAHGSENLFYQQPPLGVHSGLNHNYGNAVTGGGMDAPQASPISPHFPQDTRDGLGLPVGSKNLGQMDTSRQGGWGSHAGPGNHVQLRGNLANSNMMWGAPAQAEPTDGYQYTYSQASEIRTQKLTSGVLHKLDSFTQVFANQNLRIQVNNMAQVLHTQSAVMDGAPDSALRQLLSQKPMEPPAPAIPSRYQQVPQQPHPGFTGGLSKPALQVGQHPTQGHLYYDYQQPLAQVPVQGGQPLQAPQMLSQHMQQMQQHQYYPPQQQQQAGQQRISMQEIQTQPQQIRPSQPQPPPQQQQPQQLQLQQRQGSMQIPQYYQPQPMMQHLQEQQQQQMHLQPPSYHRDPHQYTPEQAHTVQLIPLGSMSQYYYQEPQQPYSHPLYQQSHLSQHQQREDSQLKTYSSDRQAQAMLSSHGDLGPPDTGMGDPASSDLTRVSSTLPHRPLLSPSGIHLNNMGPQHQQLSPSAMWPQMHLPDGRAQPGSPESSGQPKGAFGEQFDAKNKLTCSICLKEFKNLPALNGHMRSHGGMRASPNLKQEEGEKVLPPQPQPPLPPPPPPPPPPQLPPEAESLTPMVMPVSVPVKLLPPKPSSQGFTNSTVAAPSARDKPASSMSDDEMPVLEIPRKHQPSVPKAEEPLKTVQEKKKFRHRPEPLFIPPPPSYNPNPAASYSGATLYQSQLRSPRVLGDHLLLDPTHELPPYTPPPMLSPVRQGSGLFSNVLISGHGPGAHPQLPLTPLTPTPRVLLCRSNSIDGSNVTVTPGPGEQTVDVEPRINIGLRFQAEIPELQDISALAQDTHKATLVWKPWPELENHDLQQRVENLLNLCCSSALPGGGTNSEFALHSLFEAKGDVMVALEMLLLRKPVRLKCHPLANYHYAGSDKWTSLERKLFNKALATYSKDFIFVQKMVKSKTVAQCVEYYYTWKKIMRLGRKHRTRLAEIIDDCVTSEEEEELEEEEEEDPEEDRKSTKEEESEVPKSPEPPPVPVLAPTEGPPLQALGQPSGSFICEMPNCGAVFSSRQALNGHARIHGGTNQVTKARGAIPSGKQKPGGTQSGYCSVKSSPSHSTTSGETDPTTIFPCKECGKVFFKIKSRNAHMKTHRQQEEQQRQKAQKAAFAAEMAATIERTTGPVGAPGLLPLDQLSLIKPIKDVDILDDDVVQQLGGVMEEAEVVDTDLLLDDQDSVLLQGDAEL", "output": "Binds DNA and activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1."}]}
+{"id": "function_test_106", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEMKKKINLELRNRSPEEVTELVLDNCLCVNGEIEGLNDTFKELEFLSMANVELSSLARLPSLNKLRKLELSDNIISGGLEVLAEKCPNLTYLNLSGNKIKDLSTVEALQNLKNLKSLDLFNCEITNLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAEDDGEEEDD", "output": "Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AZ1 in the nucleosome. May stabilize the evicted H2A.Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state . Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis."}]}
+{"id": "function_test_107", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKTLETQPLAPDCCPSDQDPAPAHPSPHASPMNKNADSELMPPPPERGDPPRLSPDPVAGSAVSQELREGDPVSLSTPLETEFGSPSELSPRIEEQELSENTSLPAEEANGSLSEEEANGPELGSGKAMEDTSGEPAAEDEGDTAWNYSFSQLPRFLSGSWSEFSTQPENFLKGCKWAPDGSCILTNSADNILRIYNLPPELYHEGEQVEYAEMVPVLRMVEGDTIYDYCWYSLMSSAQPDTSYVASSSRENPIHIWDAFTGELRASFRAYNHLDELTAAHSLCFSPDGSQLFCGFNRTVRVFSTARPGRDCEVRATFAKKQGQSGIISCIAFSPAQPLYACGSYGRSLGLYAWDDGSPLALLGGHQGGITHLCFHPDGNRFFSGARKDAELLCWDLRQSGYPLWSLGREVTTNQRIYFDLDPTGQFLVSGSTSGAVSVWDTDGPGNDGKPEPVLSFLPQKDCTNGVSLHPSLPLLATASGQRVFPEPTESGDEGEELGLPLLSTRHVHLECRLQLWWCGGAPDSSIPDDHQGEKGQGGTEGGVGELI", "output": "RNA chaperone that plays a key role in telomere maintenance and RNA localization to Cajal bodies . Specifically recognizes and binds the Cajal body box (CAB box) present in both small Cajal body RNAs (scaRNAs) and telomerase RNA template component (TERC) . Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes . In the telomerase holoenzyme complex, required to stimulate the catalytic activity of the complex . Acts by specifically binding the CAB box of the TERC RNA and controlling the folding of the CR4/CR5 region of the TERC RNA, a critical step for telomerase activity . In addition, also controls telomerase holoenzyme complex localization to Cajal body . During S phase, required for delivery of TERC to telomeres during S phase and for telomerase activity . In addition to its role in telomere maintenance, also required for Cajal body formation, probably by mediating localization of scaRNAs to Cajal bodies . Also plays a role in DNA repair: phosphorylated by ATM in response to DNA damage and relocalizes to sites of DNA double-strand breaks to promote the repair of DNA double-strand breaks . Acts by recruiting the ubiquitin ligase RNF8 to DNA breaks and promote both homologous recombination (HR) and non-homologous end joining (NHEJ) ."}]}
+{"id": "function_test_108", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVNSCCGSVCSDQGCGLENCCRPSYCQTTCCRTTCCRPSCCVSSCCRPQCCQTTCCRTTCCHPSCCVSSCCRPQCCQSVCCQPTCCRPQCCQTTCCRTTCCRPSCCRPQCCQSVCCQPTCCCPSYCVSSCCRPQCCQTTCCRTTCCRPSCCVSRCYRPHCGQSLCC", "output": "In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins."}]}
+{"id": "function_test_109", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAELYVKPGNKERGWNDPPQFSYGLQTQAGGPRRSLLTKRVAAPQDGSPRVPASETSPGPPPMGPPPPSSKAPRSPPVGSGPASGVEPTSFPVESEAVMEDVLRPLEQALEDCRGHTRKQVCDDISRRLALLQEQWAGGKLSIPVKKRMALLVQELSSHRWDAADDIHRSLMVDHVTEVSQWMVGVKRLIAEKRSLFSEEAANEEKSAATAEKNHTIPGFQQAS", "output": "Functional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis."}]}
+{"id": "function_test_110", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGSQPPLGSPLSREEGEAPPPAPASEGRRRSRRVRLRGSCRHRPSFLGCRELAASAPARPAPASSEIMASAAKEFKMDNFSPKAGTSKLQQTVPADASPDSKCPICLDRFDNVSYLDRCLHKFCFRCVQEWSKNKAECPLCKQPFDSIFHSVRAEDDFKEYVLRPSYNGSFVTPDRRFRYRTTLTRERNASVYSPSGPVNRRTTTPPDSGVLFEGLGISTRPRDVEIPQFMRQIAVRRPTTADERSLRKIQEQDIINFRRTLYRAGARVRNIEDGGRYRDISAEFFRRNPACLHRLVPWLKRELTVLFGAHGSLVNIVQHIIMSNVTRYDLESQAFVSDLRPFLLNRTEHFIHEFISFARSPFNMAAFDQHANYDCPAPSYEEGSHSDSSVITISPDEAETQELDINVATVSQAPWDDETPGPSYSSSEQVHVTMSSLLNTSDSSDEELVTGGATSQIQGVQTNDDLNNDSDDSSDNCVIVGFVKPLAERTPELVELSSDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASRSPVVITIDSDSDKDSEVKEDTECDNSGPQDPLQNEFLAPSLEPFETKDVVTIEAEFGVLDKECDIATLSNNLNNANKTVDNIPPLAASVEQTLDVREESTFVSDLENQPSNIVSLQTEPSRQLPSPRTSLMSVCLGRDCDMS", "output": "Functions as an E3 ubiquitin-protein ligase and as an E3 SUMO1-protein ligase. Probable tumor suppressor involved in cell growth, cell proliferation and apoptosis that regulates p53/TP53 stability through ubiquitin-dependent degradation. May regulate chromatin modification through sumoylation of several chromatin modification-associated proteins. May be involved in DNA damage-induced cell death through IKBKE sumoylation."}]}
+{"id": "function_test_111", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSLLNCENSCGSSQSESDCCVAMASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEFDPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPDNFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILKDCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPIPCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIHQLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV", "output": "E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2 . Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation . Leads to the activation of NF-kappa-B and JUN . Seems to also play a role in dendritic cells (DCs) maturation and/or activation (By similarity). Represses c-Myb-mediated transactivation, in B-lymphocytes . Adapter protein that seems to play a role in signal transduction initiated via TNF receptor, IL-1 receptor and IL-17 receptor . Regulates osteoclast differentiation by mediating the activation of adapter protein complex 1 (AP-1) and NF-kappa-B, in response to RANK-L stimulation (By similarity). Together with MAP3K8, mediates CD40 signals that activate ERK in B-cells and macrophages, and thus may play a role in the regulation of immunoglobulin production (By similarity). Participates also in the TCR signaling by ubiquitinating LAT ."}]}
+{"id": "function_test_112", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGLHFKWPLGAPMLAAIYAMSMVLKMLPALGMACPPKCRCEKLLFYCDSQGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWLHLDHNQISTVKEDAFQGLYKLKELILSSNKIFYLPNTTFTQLINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDLTVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGNLWECSARICALASWLGSFQGRWEHSILCHSPDHTQGEDILDAVHGFQLCWNLSTTVTVMATTYRDPTTEYTKRISSSSYHVGDKEIPTTAGIAVTTEEHFPEPDNAIFTQRVITGTMALLFSFFFIIFIVFISRKCCPPTLRRIRQCSMVQNHRQLRSQTRLHMSNMSDQGPYNEYEPTHEGPFIIINGYGQCKCQQLPYKECEV", "output": "Involved in the development and maintenance of excitatory synapses in the vertebrate nervous system. Regulates surface expression of AMPA receptors and instructs the development of functional glutamate release sites. Acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B (By similarity)."}]}
+{"id": "function_test_113", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSSSRPEPGPWAPLSPRLQPLSQSSSSLLGEGREQRPELRKTASSTVWQAQLGEASTRPQAPEEEGNPPESMKPARASGPKARPSAGGHWWSSTVGNVSTMGGSDLCRLRAPSAAAMQRSHSDLVRSTQMRGHSGARKASLSCSALGSSPVHRAQLQPGGTSGQGGQAPAGLERDLAPEDETSNSAWMLGASQLSVPPLDLGDTTAHSSSAQAEPKAAEQLATTTCHALPPAALLCGMREVRAGGCCHALPATGILAFPKLVASVSESGLQAQHGVKIHCRLSGGLPGHSHCCAHLWGPAGLVPEPGSRTKDVWTMTSANDLAPAEASPLSAQDAGVQAAPVAACKAVATSPSLEAPAALHVFPEVTLGSSLEEVPSPVRDVRWDAEGMTWEVYGAAVDLEVLGVAIQKHLEMQFEQLQRAPASEDSLSVEGRRGPLRAVMQSLRRPSCCGCSGAAPE", "output": "May be involved in neurite outgrowth."}]}
+{"id": "function_test_114", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGCFFSKRRKADKESRPENEEERPKQYSWDQREKVDPKDYMFSGLKDETVGRLPGTVAGQQFLIQDCENCNIYIFDHSATVTIDDCTNCIIFLGPVKGSVFFRNCRDCKCTLACQQFRVRDCRKLEVFLCCATQPIIESSSNIKFGCFQWYYPELAFQFKDAGLSIFNNTWSNIHDFTPVSGELNWSLLPEDAVVQDYVPIPTTEELKAVRVSTEANRSIVPISRGQRQKSSDESCLVVLFAGDYTIANARKLIDEMVGKGFFLVQTKEVSMKAEDAQRVFREKAPDFLPLLNKGPVIALEFNGDGAVEVCQLIVNEIFNGTKMFVSESKETASGDVDSFYNFADIQMGI", "output": "Acts as a GTPase-activating protein (GAP) involved in trafficking between the Golgi and the ciliary membrane. Involved in localization of proteins, such as NPHP3, to the cilium membrane by inducing hydrolysis of GTP ARL3, leading to the release of UNC119 (or UNC119B). Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor towards ADP-ribosylation factor-like proteins."}]}
+{"id": "function_test_115", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAANMYRVGDYVYFENSSSNPYLVRRIEELNKTANGNVEAKVVCLFRRRDISSSLNSLADSNAREFEEESKQPGVSEQQRHQLKHRELFLSRQFESLPATHIRGKCSVTLLNETDILSQYLEKEDCFFYSLVFDPVQKTLLADQGEIRVGCKYQAEIPDRLVEGESDNRNQQKMEMKVWDPDNPLTDRQIDQFLVVARAVGTFARALDCSSSIRQPSLHMSAAAASRDITLFHAMDTLQRNGYDLAKAMSTLVPQGGPVLCRDEMEEWSASEAMLFEEALEKYGKDFNDIRQDFLPWKSLASIVQFYYMWKTTDRYIQQKRLKAAEADSKLKQVYIPTYTKPNPNQIISVGSKPGMNGAGFQKGLTCESCHTTQSAQWYAWGPPNMQCRLCASCWIYWKKYGGLKTPTQLEGATRGTTEPHSRGHLSRPEAQSLSPYTTSANRAKLLAKNRQTFLLQTTKLTRLARRMCRDLLQPRRAARRPYAPINANAIKAECSIRLPKAAKTPLKIHPLVRLPLATIVKDLVAQAPLKPKTPRGTKTPINRNQLSQNRGLGGIMVKRAYETMAGAGVPFSANGRPLASGIRSSSQPAAKRQKLNPADAPNPVVFVATKDTRALRKALTHLEMRRAARRPNLPLKVKPTLIAVRPPVPLPAPSHPASTNEPIVLED", "output": "May function as a transcriptional coregulator . Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin ."}]}
+{"id": "function_test_116", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEECERAVIDFVAFQDISIKRLQRLLQALEAPEGWGPTPRAGRAALQLKLRRRLTELLGAQDGALLVRLLQALRVARMPGLERSVRERFLPVH", "output": "Decoy receptor that can neutralize the cytotoxic ligands TNFS14/LIGHT, TNFSF15 and TNFSF6/FASL. Protects against apoptosis."}]}
+{"id": "function_test_117", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLPPGTATLLTLLLAAGSLGQKPQRPRRPASPISTIQPKANFDAQQFAGTWLLVAVGSACRFLQEQGHRAEATTLHVAPQGTAMAVSTFRKLDGICWQVRQLYGDTGVLGRFLLQARDARGAVHVVVAETDYQSFAVLYLERAGQLSVKLYARSLPVSDSVLSGFEQRVQEAHLTEDQIFYFPKYGFCEAADQFHVLDEVRR", "output": "C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol."}]}
+{"id": "function_test_118", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSTGGDFGNPLRKFKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALPGMESTQDRSREDMIDIKLEKPQEQPVSEGGCSC", "output": "Regulator of COPI-independent retrograde transport from the Golgi apparatus towards the endoplasmic reticulum (ER) . Has a low GTPase activity . Recruits VPS13B to the Golgi membrane . Plays a role in neuron projection development (Probable)."}]}
+{"id": "function_test_119", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGSACIKVTKYFLFLFNLIFFILGAVILGFGVWILADKSSFISVLQTSSSSLRMGAYVFIGVGAVTMLMGFLGCIGAVNEVRCLLGLYFAFLLLILIAQVTAGALFYFNMGKLKQEMGGIVTELIRDYNSSREDSLQDAWDYVQAQVKCCGWVSFYNWTDNAELMNRPEVTYPCSCEVKGEEDNSLSVRKGFCEAPGNRTQSGNHPEDWPVYQEGCMEKVQAWLQENLGIILGVGVGVAIIELLGMVLSICLCRHVHSEDYSKVPKY", "output": "Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway."}]}
+{"id": "function_test_120", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRFTFTSRCLALFLLLNHPTPILPAFSNQTYPTIEPKPFLYVVGRKKMMDAQYKCYDRMQQLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEKVTKYCDEKGVWFKHPENNRTWSNYTMCNAFTPEKLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVFPWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGRRPSNRSARAAAAAAEAGDIPIYICHQELRNEPANNQGEESAEIIPLNIIEQESSA", "output": "This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin.; "}]}
+{"id": "function_test_121", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAEDEPDAKSPKTGGRAPPGGAEAGEPTTLLQRLRGTISKAVQNKVEGILQDVQKFSDNDKLYLYLQLPSGPTTGDKSSEPSTLSNEEYMYAYRWIRNHLEEHTDTCLPKQSVYDAYRKYCESLACCRPLSTANFGKIIREIFPDIKARRLGGRGQSKYCYSGIRRKTLVSMPPLPGLDLKGSESPEMGPEVTPAPRDELVEAACALTCDWAERILKRSFSSIVEVARFLLQQHLISARSAHAHVLKAMGLAEEDEHAPRERSSKPKNGLENPEGGAHKKPERLAQPPKDLEARTGAGPLARGERKKSVVESSAPGANNLQVNALVARLPLLLPRAPRSLIPPIPVSPPILAPRLSSGALKVATLPLSSRAGAPPAAVPIINMILPTVPALPGPGPGPGRAPPGGLTQPRGTENREVGIGGDQGPHDKGVKRTAEVPVSEASGQAPPAKAAKQDIEDTASDAKRKRGRPRKKSGGSGERNSTPLKSAAAMESAQSSRLPWETWGSGGEGNSAGGAERPGPMGEAEKGAVLAQGQGDGTVSKGGRGPGSQHTKEAEDKIPLVPSKVSVIKGSRSQKEAFPLAKGEVDTAPQGNKDLKEHVLQSSLSQEHKDPKATPP", "output": "Activates transcription from class II MHC promoters. Recognizes X-boxes. Mediates cooperative binding between RFX and NF-Y. RFX binds the X1 box of MHC-II promoters."}]}
+{"id": "function_test_122", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MYSFMGGGLFCAWVGTILLVVAMATDHWMQYRLSGSFAHQGLWRYCLGNKCYLQTDSIAYWNATRAFMILSALCAISGIIMGIMAFAHQPTFSRISRPFSAGIMFFSSTLFVVLALAIYTGVTVSFLGRRFGDWRFSWSYILGWVAVLMTFFAGIFYMCAYRVHECRRLSTPR", "output": "Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis."}]}
+{"id": "function_test_123", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAGEEINEDYPVEIHEYLSAFENSIGAVDEMLKTMMSVSRNELLQKLDPLEQAKVDLVSAYTLNSMFWVYLATQGVNPKEHPVKQELERIRVYMNRVKEITDKKKAGKLDRGAASRFVKNALWEPKSKNASKVANKGKSKS", "output": "Plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA; this function may include MPHOSPH6. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a p53/TP53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB (By similarity)."}]}
+{"id": "function_test_124", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSKRLRSSEVCADCSGPDPSWASVNRGTFLCDECCSVHRSLGRHISQVRHLKHTPWPPTLLQMVETLYNNGANSIWEHSLLDPASIMSGRRKANPQDKVHPNKAEFIRAKYQMLAFVHRLPCRDDDSVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGNTPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPVDYARQGGHHELAERLVEIQYELTDRLAFYLCGRKPDHKNGQHFIIPQMADSSLDLSELAKAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVWLATQNHSALVTETTVVPFLPVNPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQGSSLSGSKDNVELILKTINNQHSVESQDNDQPDYDSVASDEDTDLETTASKTNRQKSLDSDLSDGPVTVQEFMEVKNALVASEAKIQQLMKVNNNLSDELRIMQKKLQTLQSENSNLRKQATTNVYQVQTGSEYTDTSNHSSLKRRPSARGSRPMSMYETGSGQKPYLPMGEASRPEESRMRLQPFPAHIGRSALVTSSSSLPSFPSTLSWSRDESARRASRLEKQNSTPESDYDNTPNDMEPDGMGSSRKGRQRSMVWPGDGLVPDTAEPHVAPSPTLPSTEDVIRKTEQITKNIQELLRAAQENKHDSYIPCSERIHVAVTEMAALFPKKPKSDMVRTSLRLLTSSAYRLQSECKKTLPGDPGSPTDVQLVTQQVIQCAYDIAKAAKQLVTITTKENNN", "output": "GTPase-activating protein for ADP ribosylation factor family members, including ARF1."}]}
+{"id": "function_test_125", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MMNRTTPDQELAPASEPVWERPWSVEEIRRSSQSWSLAADAGLLQFLQEFSQQTISRTHEIKKQVDGLIRETKATDCRLHNVFNDFLMLSNTQFIENRVYDEEVEEPVLKAEAEKTEQEKTREQKEVDLIPKVQEAVNYGLQVLDSAFEQLDIKAGNSDSEEDDANGRVELILEPKDLYIDRPLPYLIGSKLFMEQEDVGLGELSSEEGSVGSDRGSIVDTEEEKEEEESDEDFAHHSDNEQNRHTTQMSDEEEDDDGCDLFADSEKEEEDIEDIEENTRPKRSRPTSFADELAARIKGDAVGRVDEEPTTLPSGEAKPRKTLKEKKERRTPSDDEEDNLFAPPKLTDEDFSPFGSGGGLFSGGKGLFDDEDEESDLFTEAPQDRQAGASVKEESSSSKPGKKIPAGAVSVFLGDTDVFGAASVPSMKEPQKPEQPTPRKSPYGPPPTGLFDDDDGDDDDDFFSAPHSKPSKTGKVQSTADIFGDEEGDLFKEKAVASPEATVSQTDENKARAEKKVTLSSSKNLKPSSETKTQKGLFSDEEDSEDLFSSQSASKLKGASLLPGKLPTLVSLFDDEDEEDNLFGGTAAKKQTLCLQAQREEKAKASELSKKKASALLFSSDEEDQWNIPASQTHLASDSRSKGEPRDSGTLQSQEAKAVKKTSLFEEDEEDDLFAIAKDSQKKTQRVSLLFEDDVDSGGSLFGSPPTSVPPATKKKETVSEAPPLLFSDEEEKEAQLGVKSVDKKVESAKESLKFGRTDVAESEKEGLLTRSAQETVKHSDLFSSSSPWDKGTKPRTKTVLSLFDEEEDKMEDQNIIQAPQKEVGKGRDPDAHPKSTGVFQDEELLFSHKLQKDNDPDVDLFAGTKKTKLLEPSVGSLFGDDEDDDLFSSAKSQPLVQEKKRVVKKDHSVDSFKNQKHPESIQGSKEKGIWKPETPQDSSGLAPFKTKEPSTRIGKIQANLAINPAALLPTAASQISEVKPVLPELAFPSSEHRRSHGLESVPVLPGSGEAGVSFDLPAQADTLHSANKSRVKMRGKRRPQTRAARRLAAQESSETEDMSVPRGPIAQWADGAISPNGHRPQLRAASGEDSTEEALAAAAAPWEGGPVPGVDRSPFAKSLGHSRGEADLFDSGDIFSTGTGSQSVERTKPKAKIAENPANPPVGGKAKSPMFPALGEASSDDDLFQSAKPKPAKKTNPFPLLEDEDDLFTDQKVKKNETKSNSQQDVILTTQDIFEDDIFATEAIKPSQKTREKEKTLESNLFDDNIDIFADLTVKPKEKSKKKVEAKSIFDDDMDDIFSSGIQAKTTKPKSRSAQAAPEPRFEHKVSNIFDDPLNAFGGQ", "output": "Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes inhibits WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization and is involved in the fission of tubules that serve as transport intermediates during endosome sorting. Mediates the recruitment of the WASH core complex to endosome membranes via binding to phospholipids and VPS35 of the retromer CSC. Mediates the recruitment of the F-actin-capping protein dimer to the WASH core complex probably promoting localized F-actin polymerization needed for vesicle scission. Via its C-terminus binds various phospholipids, most strongly phosphatidylinositol 4-phosphate (PtdIns-(4)P), phosphatidylinositol 5-phosphate (PtdIns-(5)P) and phosphatidylinositol 3,5-bisphosphate (PtdIns-(3,5)P2). Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1. Required for the association of DNAJC13, ENTR1, ANKRD50 with retromer CSC subunit VPS35. Required for the endosomal recruitment of CCC complex subunits COMMD1 and CCDC93 as well as the retriever complex subunit VPS35L."}]}
+{"id": "function_test_126", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRPGLSFLLALLFFLGQAAGDLGDVGPPIPSPGFSSFPGVDSSSSFSSSSRSGSSSSRSLGSGGSVSQLFSNFTGSVDDRGTCQCSVSLPDTTFPVDRVERLEFTAHVLSQKFEKELSKVREYVQLISVYEKKLLNLTVRIDIMEKDTISYTELDFELIKVEVKEMEKLVIQLKESFGGSSEIVDQLEVEIRNMTLLVEKLETLDKNNVLAIRREIVALKTKLKECEASKDQNTPVVHPPPTPGSCGHGGVVNISKPSVVQLNWRGFSYLYGAWGRDYSPQHPNKGLYWVAPLNTDGRLLEYYRLYNTLDDLLLYINARELRITYGQGSGTAVYNNNMYVNMYNTGNIARVNLTTNTIAVTQTLPNAAYNNRFSYANVAWQDIDFAVDENGLWVIYSTEASTGNMVISKLNDTTLQVLNTWYTKQYKPSASNAFMVCGVLYATRTMNTRTEEIFYYYDTNTGKEGKLDIVMHKMQEKVQSINYNPFDQKLYVYNDGYLLNYDLSVLQKPQ", "output": "May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin."}]}
+{"id": "function_test_127", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKTLPLFVCICALSACFSFSEGRERDHELRHRRHHHQSPKSHFELPHYPGLLAHQKPFIRKSYKCLHKRCRPKLPPSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQTTTSVTTQTTTTKQPTSAPGQNKISRFLLYMKNLLNRIIDDMVEQ", "output": "May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili."}]}
+{"id": "function_test_128", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAGGPPNTKAEMEMSLAEELNHGRQGENQEHLVIAEMMELGSRSRGASQKKQKLEQKAAGSASAKRVWNMTATRPKKMGSQLPKPRMLRESGHGDAHLQEYAGNFQGIRFHYDRNPGTDAVAQTSLEEFNVLEMEVMRRQLYAVNRRLRALEEQGATWRHRETLIIAVLVSASIANLWLWMNQ", "output": "Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis . May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling ."}]}
+{"id": "function_test_129", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGRGWGFLFGLLGAVWLLSSGHGEEQPPETAAQRCFCQVSGYLDDCTCDVETIDRFNNYRLFPRLQKLLESDYFRYYKVNLKRPCPFWNDISQCGRRDCAVKPCQSDEVPDGIKSASYKYSEEANNLIEECEQAERLGAVDESLSEETQKAVLQWTKHDDSSDNFCEADDIQSPEAEYVDLLLNPERYTGYKGPDAWKIWNVIYEENCFKPQTIKRPLNPLASGQGTSEENTFYSWLEGLCVEKRAFYRLISGLHASINVHLSARYLLQETWLEKKWGHNITEFQQRFDGILTEGEGPRRLKNLYFLYLIELRALSKVLPFFERPDFQLFTGNKIQDEENKMLLLEILHEIKSFPLHFDENSFFAGDKKEAHKLKEDFRLHFRNISRIMDCVGCFKCRLWGKLQTQGLGTALKILFSEKLIANMPESGPSYEFHLTRQEIVSLFNAFGRISTSVKELENFRNLLQNIH", "output": "Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the proper folding of immunoglobulins . Plays an important role in ER stress-induced, CHOP-dependent apoptosis by activating the inositol 1,4,5-trisphosphate receptor IP3R1. Involved in the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae, thereby playing a role in retrotranslocation of the toxin."}]}
+{"id": "function_test_130", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSCGRPPPDVDGMITLKVDNLTYRTSPDSLRRVFEKYGRVGDVYIPREPHTKAPRGFAFVRFHDRRDAQDAEAAMDGAELDGRELRVQVARYGRRDLPRSRQGEPRGRSRGGGYGRRSRSYGRRSRSPRRRHRSRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRESRYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKSSSARRSKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKSRSRSKRPPKSPEEEGQMSS", "output": "Involved in pre-mRNA alternative splicing."}]}
+{"id": "function_test_131", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPAFNRLFPLASLVLIYWVSVCFPVCVEVPSETEAVQGNPMKLRCISCMKREEVEATTVVEWFYRPEGGKDFLIYEYRNGHQEVESPFQGRLQWNGSKDLQDVSITVLNVTLNDSGLYTCNVSREFEFEAHRPFVKTTRLIPLRVTEEAGEDFTSVVSEIMMYILLVFLTLWLLIEMIYCYRKVSKAEEAAQENASDYLAIPSENKENSAVPVEE", "output": "Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons (By similarity)."}]}
+{"id": "function_test_132", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTSEEMTASVLIPVTQRKVVSAQSAADESSEKVSDINISKAHTVRRSGETSHTISQLNKLKEEPSGSNLPKILSIAREKIVSDENSNEKCWEKIMPDSAKNLNINCNNILRNHQHGLPQRQFYEMYNSVAEEDLCLETGIPSPLERKVFPGIQLELDRPSMGISPLGNQSVIIETGRAHPDSRRAVFHFHYEVDRRMSDTFCTLSENLILDDCGNCVPLPGGEEKQKKNYVAYTCKLMELAKNCDNKNEQLQCDHCDTLNDKYFCFEGSCEKVDMVYSGDSFCRKDFTDSQAAKTFLSHFEDFPDNCDDVEEDAFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLTAWSYIDQKRNGPLLPCGRVMEPPSTVEIRQDGSQRLSEAQWYPIYNAVRREETENTVGSLLHFLTKLPASETAHGRISVGPCLKQCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGARSGLLSTFGGSTGRMMLKERQPGPSVANSNALPSSSAGISKELIDLQPLIQFPEEVASILMEQEQTIYRRVLPVDYLCFLTRDLGTPECQSSLPCLKASISASILTTQNGEHNALEDLVMRFNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQFMDQSDIETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGASGLMKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQVIRSCNRSLETDEEDSPSEGNSSRKSSLKDKSRWQFIIGDLLDSDNDIFEQSKEYDSHGSEDSQKAFDHGTELIPWYVLSIQADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWVKPTTASPASSKAKLGVLNNTAEPGKFPLLGNAGLSSLTEGVLDLFAVKAVYMGHPGIDIHTVCVQNKLGSMFLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQQWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSARNPSPGTSAKNAEKPNMQRNNTLGISTTKKKKKILMRGESGEVTDDEMATRKAKMHKECRSRSGSDPQDINEQEESEVNAIANPPNPLPSRRAHSLTTAGSPNLAAGTSSPIRPVSSPVLSSSNKSPSSAWSSSSWHGRIKGGMKGFQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDVYAVPCNRSGSESAPLYTNLTIDENTSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSLGIFGVGILQLNDFLVNCQGEHCTYDEILSIIQKFEPSISMCHQGLMSFEGFARFLMDKENFASKNDESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTVFGEKLVTKFLFETDFSDDPMLPSPDQLRKKVLLKNKKLKAHQTPVDILKQKAHQLASMQVQAYNGGNANPRPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEEIPKRIKKADNSACNKGKVYDMELGEEFYLDQNKKESRQIAPELSDLVIYCQAVKFPGLSTLNASGSSRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSCEGIRQTWEESSSPLNPTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLTQHTACQLLRTYPAATRIDSSNPNPLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDSMDPAVYSLTIVSGQNVCPSNSMGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQFLFHVHFEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFINSRRMEENSSGNTMSASSMFNTEERKCLQTHRVTVHGVPGPEPFTVFTINGGTKAKQLLQQILTNEQDIKPVTTDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIMQILSSWFPEEGYMGRIVLKTQQENLEEKNIVQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTTNKKTTTPKSSQRVLLDQECVFQAQSKWKGAGKFILKLKEQVQASREDKKKGISFASELKKLTKSTKQPRGLTSPSQLLTSESIQTKEEKPVGGLSSSDTMDYRQ", "output": "The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. PLCE1 is a bifunctional enzyme which also regulates small GTPases of the Ras superfamily through its Ras guanine-exchange factor (RasGEF) activity. As an effector of heterotrimeric and small G-protein, it may play a role in cell survival, cell growth, actin organization and T-cell activation. In podocytes, is involved in the regulation of lamellipodia formation. Acts downstream of AVIL to allow ARP2/3 complex assembly ."}]}
+{"id": "function_test_133", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLPRLICINDYEQHAKSVLPKSIYDYYRSGANDEETLADNIAAFSRWKLYPRMLRNVAETDLSTSVLGQRVSMPICVGATAMQRMAHVDGELATVRACQSLGTGMMLSSWATSSIEEVAEAGPEALRWLQLYIYKDREVTKKLVRQAEKMGYKAIFVTVDTPYLGNRLDDVRNRFKLPPQLRMKNFETSTLSFSPEENFGDDSGLAAYVAKAIDPSISWEDIKWLRRLTSLPIVAKGILRGDDAREAVKHGLNGILVSNHGARQLDGVPATIDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGRPIVWGLAFQGEKGVQDVLEILKEEFRLAMALSGCQNVKVIDKTLVRKNPLAVSKI", "output": "Broad substrate specificity (S)-2-hydroxy-acid oxidase that preferentially oxidizes glycolate . The glyoxylate produced by the oxidation of glycolate can then be utilized by alanine-glyoxylate aminotransferase for the peroxisomal synthesis of glycine; this pathway appears to be an important step for the detoxification of glyoxylate which, if allowed to accumulate, may be metabolized to oxalate with formation of kidney stones . Can also catalyze the oxidation of glyoxylate, and long chain hydroxyacids such as 2-hydroxyhexadecanoate and 2-hydroxyoctanoate, albeit with much lower catalytic efficiency . Active in vitro with the artificial electron acceptor 2,6-dichlorophenolindophenol (DCIP), but O2 is believed to be the physiological electron acceptor, leading to the production of H2O2 . Is not active on L-lactate and 2-hydroxybutanoate ."}]}
+{"id": "function_test_134", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MREIVHIQIGQCGNQIGAKFWEVIGEEHGIDCAGSYCGTSALQLERISVYYNEAYGKKYVPRAVLVDLEPGTMDSIRSSRLGVLFQPDSFVHGNSGAGNNWAKGHYTEGAELIENVMDVVRRESESCDCLQGFQIVHSLGGGTGSGMGTLLMNKIREEYPDRILNSFSVMPSPKVSDTVVEPYNAVLSIHQLIENTDACFCIDNEALYDICFRTLRLTTPTYGDLNHLVSLTMSGITTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTAQGSQQYRALSVAELTQQMFDARNIMAACDPRRGRYLTVACIFRGKMSTKEVDQQLLSIQTRNSNCFVEWIPNNVKVAVCDIPPRGLNMAATFLGNNTAIQELFTRVSEHFSAMFRRRAFVHWYTSEGMDISEFGEAESDIHDLVSEYQQFQDVRAGLEDSEEDVEEAEVEAEDKDH", "output": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin."}]}
+{"id": "function_test_135", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MADSVAAGLGDENETENEDKEREKRLFSGVKKMEKQAAASDVTETLGFYERKAKCKDRKTNVSDLSLVRFISAELTRGYFLEHNEAKYTERRERVYTCLRIPKELEKLMIFGYFLCLDVFLYVFTLLPLRVLLALVRLLTLPCCGLSGSRILQPAQVCDVLKGFIMVLCYFMMHYVDYSMMYHLIRGQSVIKLYIIYNMLEVADRLFSSFGQDILDALYWTATEPKERKRAHIGVIPHFFMAVLYVFLHAILIMVQATTLNVAFNSHNKSLLTIMMSNNFVEIKGSVFKKFEKNNLFQMSNSDIKERFTNYTLLLIVCLRNMEQFSWNPDHLWVLFPDVCMVIASEIAVDVVKHAFITKFNDITADVYSEYRASLAFDLVSSRQKNAYTDYSDSVSRRMGFIPLPLALLLIRVVTSSVKIQGSLSIVCVLLFYLGMITLKVLNSIVLLGKSCMYVKEANMEEKLFQNPPSAAPSRVSSRAHRTKHTREPPGDPAEEGMSASVTTQPTQQDECPAPQIPTSESDQFLTTPDESEEKSLIQDDSELKHRAPKKDLLEIDRFTICGNRID", "output": "Plays a role in primary cilia formation . Involved in cartilage and bone development . May play a role in the differentiation of cranial neural crest cells . May act as a downstream effector of hoxc8 during development (By similarity)."}]}
+{"id": "function_test_136", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAEAEAGGDEVRCVRLSAERAKLLLAEVDTLLFDCDGVLWRGETAVPGAPETLRALRARGKRLGFITNNSSKTRTAYAEKLRRLGFGGPMGPEAGLEVFGTAYCSALYLRQRLAGVPDPKAYVLGSPALAAELEAVGVTSVGVGPDVLHGDGPSDWLAVPLEPDVRAVVVGFDPHFSYMKLTKAVRYLQQPDCLLVGTNMDNRLPLENGRFIAGTGCLVRAVEMAAQRQADIIGKPSRFIFDCVSQEYGINPERTVMVGDRLDTDILLGSTCSLKTILTLTGVSSLEDVKSNQESDCMFKKKMVPDFYVDSIADLLPALQG", "output": "Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3-phosphate into glycerol . Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear (By similarity). In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP (By similarity)."}]}
+{"id": "function_test_137", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MANIESEAVDFEPEEDDLMDEEGTAIDGADVSPRAGHPRLKSAIAGANGESAKKTKGRGFREEKDSDRQRRLSSRDFESLGSDGRPGPQRSVEGWIILVSGVHEETQEEDITNAFGDFGEIKNLNLNLDRRSGYVKGYALIEYEKKEEAQSAISAMNGAELLTQNVSVDWAFSSGPSGGESYRRKNSRYGRSQRSRSPRRRY", "output": "Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all stages of mRNA metabolism thereby influencing downstream processes including nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD). The MAGO-Y14 heterodimer inhibits the ATPase activity of EIF4A3, thereby trapping the ATP-bound EJC core onto spliced mRNA in a stable conformation. The MAGO-Y14 heterodimer interacts with the EJC key regulator PYM leading to EJC disassembly in the cytoplasm (By similarity). Can increase in vitro the expression from reporter constructs that contain leader introns required for the expression of different genes. In association with MAGO and PYM, participates in intron-mediated enhancement of gene expression . The MAGO-Y14 heterodimer works synergistically with the NMD pathway to regulate male gametophyte development ."}]}
+{"id": "function_test_138", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKKQKSFPMSAYEDLLGKITAPTITVENWEGILAFCDMINNDFEGSKTGIKSLRKRLNNRDPHVVLLAISVLDSCWANCEERFRKEVSSAQFINELKALCTSSQRQVAEKMRLTVQKWVDTECKTEQSLSLIVTLHKNLVADGYSFVVDDPKSKTKAIDAKFANDPNYVGSAQEEEAIAKAIAASLADAEKQEKAKKSTSTMYPSAKASSPAVQTNSNIPEKNVRALYDFEAAESNELSFVAGDIITITDESNPHWWTGRIGTQQGLFPSSFVTNQLDDLKSKETDSSQKAPEVVASINEAILVRCLQVLHECDPTGERQDPEDLAQLEAASYAQGNLIDAHLASIDRQSNSLAQIDVAIRDVLALYDDAIQKGGFQHQSQGMYQQPMQQYNYQQPPNRAYYPPTGPVQQQQPQQYPPQHYPAPGAQPQYACPPNSVPQPQQQQQQWPAPSSQPQQY", "output": "Binds, sorts and targets the polycystin complex (lov-1 and pkd-2) for lysosomal degradation, acting on early endosomes located at the ciliary base. Functions in the germline together with the ephrin receptor (vab-1) signaling pathway to negatively regulate MAPK activation. May have a role as a positive regulator of meiotic maturation in oocytes, acting independently of vab-1."}]}
+{"id": "function_test_139", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVTLASGPAPARCLPGHKEEEDGEGAGSGEQGSGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAPVNALVSHLLVVEPEKLYAMPDPASPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGDLGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEAMMD", "output": "Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle (By similarity)."}]}
+{"id": "function_test_140", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKLLAITSCPNGIAHTYMAAENLQKAADRLGVSIKVETQGGIGVENKLTEEEIREADAIIIAADRSVNKDRFIGKKLLSVGVQDGIRKPEELIQKALNGDIPVYRSATKSESGNHQEKKQNPIYRHLMNGVSFMVPFIVVGGLLIAVALTLGGEKTPKGLVIPDDSFWKTIEQIGSASFSFMIPILAGYIAYSIADKPGLVPGMIGGYIAATGSFYDSASGAGFLGGIIAGFLAGYAALWIKKLKVPKAIQPIMPIIIIPVFASLIVGLAFVFLIGAPVAQIFASLTVWLAGMKGSSSILLALILGAMISFDMGGPVNKVAFLFGSAMIGEGNYEIMGPIAVAICIPPIGLGIATFLGKRKFEASQREMGKAAFTMGLFGITEGAIPFAAQDPLRVIPSIMAGSMTGSVIAMIGNVGDRVAHGGPIVAVLGAVDHVLMFFIAVIAGSLVTALFVNVLKKDITASPVLSETAPTSAPSEAAAANEIKQPIQSQKAEMSEFKKLTDIISPELIEPNLSGETSDDIIDELIQKLSRRGALLSESGFKQAILNREQQGTTAIGMNIAIPHGKSEAVREPSVAFGIKRSGVDWNSLDGSEAKLIFMIAVPKESGGNQHLKILQMLSRKLMDDNYRERLLSVQTTEEAYKLLEEIE", "output": "The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in mannose transport."}]}
+{"id": "function_test_141", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAFANFRRILRLSTFEKRKSREYEHVRRDLDPNDVWEIVGELGDGAFGKVYKAKNKETGALAAAKVIETKSEEELEDYIVEIEILATCDHPYIVKLLGAYYYDGKLWIMIEFCPGGAVDAIMLELDRGLTEPQIQVVCRQMLEALNFLHGKRIIHRDLKAGNVLMTLEGDIRLADFGVSAKNLKTLQKRDSFIGTPYWMAPEVVLCETMKDAPYDYKADIWSLGITLIEMAQIEPPHHELNPMRVLLKIAKSDPPTLLTPSKWSVEFRDFLKIALDKNPETRPSAAQLLQHPFVSRVTSNKALRELVAEAKAEVMEEIEDGREDGEEEDAVDAVPPLVNHTQDSANVTQPSLDSNKLLQDSSTPLPPSQPQEPVSGSCSQPSGDGPLQTTSPADGLSKNDNDLKVPVPLRKSRPLSMDARIQMDEEKQIPDQDENPSPAASKSQKANQSRPNSSALETLGGEALTNGGLELPSSVTPSHSKRASDCSNLSTSESMDYGTSLSADLSLNKETGSLSLKGSKLHNKTLKRTRRFVVDGVEVSITTSKIISEDEKKDEEMRFLRRQELRELRLLQKEEHRNQTQLSSKHELQLEQMHKRFEQEINAKKKFYDVELENLERQQKQQVEKMEQDHSVRRKEEAKRIRLEQDRDYAKFQEQLKQMKKEVKSEVEKLPRQQRKESMKQKMEEHSQKKQRLDRDFVAKQKEDLELAMRKLTTENRREICDKERDCLSKKQELLRDREAALWEMEEHQLQERHQLVKQQLKDQYFLQRHDLLRKHEKEREQMQRYNQRMMEQLKVRQQQEKARLPKIQRSDGKTRMAMYKKSLHINGAGSASEQREKIKQFSQQEEKRQKAERLQQQQKHENQMRDMVAQCESNMSELQQLQNEKCHLLVEHETQKLKALDESHNQSLKEWRDKLRPRKKALEEDLNQKKREQEMFFKLSEEAEPRPTTPSKASNFFPYSSGDAS", "output": "Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo."}]}
+{"id": "function_test_142", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTTEVGSASEVKKGSDQAGADASKEKAKEVENEQTPVSEPEEEKGSQPGPPVERQSTPRLRKRGKDPSENRGISRFIPPWLKKQRSYNLVVAKDGGDKKEPTQADVEDQILGKEESLPEEESRAKGDAEEMAQRKHLEVQVEVREAKPALKSSVETQPAEEVRKDKEETIQDTQEEKLEGGAAKRETKEVQTSELKAEVASQKATKKTKTVLAKVTLLDGTEYSCDLEKRAKGQVLFDRVCEHLNLLEKDYFGLLFQDHPEQKNWLDPAKEIKRQLKNLPWLFTFNVKFYPPDPSQLTEDITRYFLCLQLRQDIASGRLPCSFVTHALLGSYTLQAEHGDYDPEEYDSIDLGDFQFAPAHTKELEEKVSELHKTHRGLSPAQADSQFLENAKRLSMYGVDLHHAKDSEGVDIKLGVCANGLLIYKDRLRINRFAWPKILKISYKRSNFYIKVRPAELEQFESTIGFKLPNHRAAKRLWKVCVEHHTFYRLVSPEQPPKTKFLTLGSKFRYSGRTQAQTREASTLIDRPAPQFERASSKRVSRSLDGAPIGVVDQSPPGEGSVPGPGVISYTTIQDGRRDSKSPTKATPLPAEGKKNTLRVDGDNIYVRHSNLMLEDLDKAQEAILKHQASISELKRNFMASTPEPRPSEWEKRRVTPLPFQPQASSHETLNVVEEKKRAEVGKDESVITEEMNGKEMSPGHGPGETRKVEPVAHKDSTSLSSESSSSSSESEEDVGEYQPHHRVTEGTIREEQEECDEELEEEPGQGAKVVEREAAVPDAVPDRQAGASVLPVETEAQEHVVAQKLPGEKGAHGGTAEQDPREEAEEDPHRVNGEVPHLDLDGLPEIICCSEPPVVKTEMVTISDASQRTEISTKEVPIVQTETKTITYESPQIDGGAGGDSGVLLTAQTITSESASTTTTTHITKTVKGGISETRIEKRIVITGDAALDHDQALAQAIREAREQHPDMSVTRVVVHKETELAEEGEE", "output": "Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase."}]}
+{"id": "function_test_143", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSSGSRPSSGGGGGGGGASGGAGGGAPGGGGGGIRGFFSKLRKPSDQPNGNQVQVGTRTFEAHELQKLIPQLEEAISRKDAQLRQQQTIVEGHIKRISELEGEVTTLQRECDKLRSVLEQKAQSAASPGGQPPSPSPRTDQLGNDLQQKAVLPADGVQRAKKIAVSAEPTNFENKPATLQHYNKTVGAKQMIRDAVQKNDFLKQLAKEQIIELVNCMYEMRARAGQWVIQEGEPGDRLFVVAEGELQVSREGALLGKMRAGTVMGELAILYNCTRTASVQALTDVQLWVLDRSVFQMITQRLGMERHSQLMNFLTKVSIFQNLSEDRISKMADVMDQDYYDGGHYIIRQGEKGDAFFVINSGQVKVTQQIEGETEPREIRVLNQGDFFGERALLGEEVRTANIIAQAPGVEVLTLDRESFGKLIGDLESLKKDYGDKERLAQVVREPPSPVKIVDDFREEFAQVTLKNVKRLATLGVGGFGRVELVCVNGDKAKTFALKALKKKHIVDTRQQEHIFAERNIMMETSTDWIVKLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYLHRKNIVYRDLKPENCLLANTGYLKLVDFGFAKKLASGRKTWTFCGTPEYVSPEIILNKGHDQAADYWALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATALVKKLCRDNPGERLGSGSGGVNDIRKHRWFMGFDWEGLRSRTLKPPILPKVSNPADVTNFDNYPPDNDVPPDEFSGWDEGF", "output": "Promotes chemoreceptor gene expression in response to increased cGMP levels by antagonizing the gene repression functions of the class II HDAC hda-4 and the mef-2 transcription factor . Regulates gene expression via recruitment of a histone deacetylase complex containing hda-2, saeg-1 and saeg-2 . Represses body size and lifespan through the dbl-1 and insulin pathways, respectively . May also signal through daf-3 and/or daf-5. Role in egg-laying, dauer formation and motility . Regulates behavioral responses to various chemosensory stimuli in sensory neurons . Required for the initiation of long term adaptation to prolonged odor exposure which results in a decrease in odor seeking behavior . May regulate this process by phosphorylating tax-2, a subunit of cyclic nucleotide-gated channel tax-2/tax-4 . In ASH sensory neurons, negatively regulates avoidance behavior to some bitter tastants, such as quinine, probably by phosphorylating rgs-2 and rgs-3 which are 2 regulator of G-protein signaling proteins . In AWB sensory neurons, involved in avoidance behavior to some repellent odors . In ASE left (ASEL) sensory neuron, involved in the sensing of environmental alkalinity downstream of receptor-type guanylate cyclase gcy-14 . In sensory neurons, involved in the signaling pathway downstream of insulin, TGF-beta and receptor-type guanylate cyclase responsible for inducing quiescence after food intake . Might play a role in aversive olfactory learning in AWC neurons when an odor is associated with food deprivation, depending on the ins-1/age-1 signal from the AIA to the AWC neurons . Probably by regulating neuronal transmission downstream of lin-3 and receptor lin-23 and phospholipase plc-3 in ALA neurons, involved in the decrease in locomotion during the quiescent state that precedes each larval molt ."}]}
+{"id": "function_test_144", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRSALAQEATQQHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLKGDMGDVQHFADDVIAQRGVRHGHLQCLPKED", "output": "Transcriptional repressor of the nikABCDE operon. Is active in the presence of excessive concentrations of intracellular nickel."}]}
+{"id": "function_test_145", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIATGATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTNGLFITLPEDDLSFQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLDAKEHGAVILTAHEVTGLIREGATVCGVRVRNHLTGETQALHAPVVVNAAGIWGQHIAEYADLRIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYNEIDDNRVTAEEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCTTADLALPGSQEPAEVTLRKVISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVENLNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTSAQSIEQLSTFLNERWKGVQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL", "output": "Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor."}]}
+{"id": "function_test_146", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRQLPAGPSSLACSGCKAGRLVTVPFSSRDAEDQGSREGIGWQPPGRSWAHTTEQEGKHQVAKATVHPPGPDALLLNQVDPVQCCPTRL", "output": "Unknown for isoform 4. Csen is involved in calcium-dependent transcriptional repression, regulation of potassium channels, and perhaps in processing of PSEN2 and apoptosis."}]}
+{"id": "function_test_147", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSDAVTIRTRKVISNPLLARKQFVVDVLHPNRANVSKDELREKLAEVYKAEKDAVSVFGFRTQFGGGKSVGFGLVYNSVAEAKKFEPTYRLVRYGLAEKVEKASRQQRKQKKNRDKKIFGTGKRLAKKVARRNAD", "output": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel."}]}
+{"id": "function_test_148", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSQRKFAGLRDNFNLLGEKNKILVANRGEIPIRIFRTAHELSMQTVAIYSHEDRLSTHKQKADEAYVIGEVGQYTPVGAYLAIDEIISIAQKHQVDFIHPGYGFLSENSEFADKVVKAGITWIGPPAEVIDSVGDKVSARNLAAKANVPTVPGTPGPIETVEEALDFVNEYGYPVIIKAAFGGGGRGMRVVREGDDVADAFQRATSEARTAFGNGTCFVERFLDKPKHIEVQLLADNHGNVVHLFERDCSVQRRHQKVVEVAPAKTLPREVRDAILTDAVKLAKECGYRNAGTAEFLVDNQNRHYFIEINPRIQVEHTITEEITGIDIVAAQIQIAAGASLPQLGLFQDKITTRGFAIQCRITTEDPAKNFQPDTGRIEVYRSAGGNGVRLDGGNAYAGTIISPHYDSMLVKCSCSGSTYEIVRRKMIRALIEFRIRGVKTNIPFLLTLLTNPVFIEGTYWTTFIDDTPQLFQMVSSQNRAQKLLHYLADVAVNGSSIKGQIGLPKLKSNPSVPHLHDAQGNVINVTKSAPPSGWRQVLLEKGPAEFARQVRQFNGTLLMDTTWRDAHQSLLATRVRTHDLATIAPTTAHALAGRFALECWGGATFDVAMRFLHEDPWERLRKLRSLVPNIPFQMLLRGANGVAYSSLPDNAIDHFVKQAKDNGVDIFRVFDALNDLEQLKVGVDAVKKAGGVVEATVCFSGDMLQPGKKYNLDYYLEIAEKIVQMGTHILGIKDMAGTMKPAAAKLLIGSLRAKYPDLPIHVHTHDSAGTAVASMTACALAGADVVDVAINSMSGLTSQPSINALLASLEGNIDTGINVEHVRELDAYWAEMRLLYSCFEADLKGPDPEVYQHEIPGGQLTNLLFQAQQLGLGEQWAETKRAYREANYLLGDIVKVTPTSKVVGDLAQFMVSNKLTSDDVRRLANSLDFPDSVMDFFEGLIGQPYGGFPEPFRSDVLRNKRRKLTCRPGLELEPFDLEKIREDLQNRFGDVDECDVASYNMYPRVYEDFQKMRETYGDLSVLPTRSFLSPLETDEEIEVVIEQGKTLIIKLQAVGDLNKKTGEREVYFDLNGEMRKIRVADRSQKVETVTKSKADMHDPLHIGAPMAGVIVEVKVHKGSLIKKGQPVAVLSAMKMEMIISSPSDGQVKEVFVSDGENVDSSDLLVLLEDQVPVETKA", "output": "Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second."}]}
+{"id": "function_test_149", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKQRAALGPVLRLAILALLAVSYVQSQATCRDCSNRGCFCVGEKGSMGAPGPQGPPGTQGIRGFPGPEGLAGPKGLKGAQGPPGPVGIKGDRGAVGVPGFPGNDGGNGRPGEPGPPGAPGWDGCNGTDGAPGIPGRPGPPGMPGFPGPPGMDGLKGEPAIGYAGAPGEKGDGGMPGMPGLPGPSGRDGYPGEKGDRGDTGNAGPRGPPGEAGSPGNPGIGSIGPKGDPGDLGSVGPPGPPGPREFTGSGSIVGPRGNPGEKGDKGEPGEGGQRGYPGNGGLSGQPGLPGMKGEKGLSGPAGPRGKEGRPGNAGPPGFKGDRGLDGLGGIPGLPGQKGEAGYPGRDGPKGNSGPPGPPGGGTFNDGAPGPPGLPGRPGNPGPPGTDGYPGAPGPAGPIGNTGGPGLPGYPGNEGLPGPKGDKGDGGIPGAPGVSGPSGIPGLPGPKGEPGYRGTPGQSIPGLPGKDGKPGLDGAPGRKGENGLPGVRGPPGDSLNGLPGAPGQRGAPGPNGYDGRDGVNGLPGAPGTKGDRGGTCSACAPGTKGEKGLPGYSGQPGPQGDRGLPGMPGPVGDAGDDGLPGPAGRPGSPGPPGQDGFPGLPGQKGEPTQLTLRPGPPGYPGLKGENGFPGQPGVDGLPGPSGPVGPPGAPGYPGEKGDAGLPGLSGKPGQDGLPGLPGNKGEAGYGQPGQPGFPGAKGDGGLPGLPGTPGLQGMPGEPAPENQVNPAPPGQPGLPGLPGTKGEGGYPGRPGEVGQPGFPGLPGMKGDSGLPGPPGLPGHPGVPGDKGFGGVPGLPGIPGPKGDVGNPGLPGLNGQKGEPGVGVPGQPGSPGFPGLKGDAGLPGLPGTPGLEGQRGFPGAPGLKGGDGLPGLSGQPGYPGEKGDAGLPGVPGREGSPGFPGQDGLPGVPGMKGEDGLPGLPGVTGLKGDLGAPGQSGAPGLPGAPGYPGMKGNAGIPGVPGFKGDGGLPGLPGLNGPKGEPGVPGMPGTPGMKGNGGLPGLPGRDGLSGVPGMKGDRGFNGLPGEKGEAGPAARDGQKGDAGLPGQPGLRGPQGPSGLPGVPGFKGETGLPGYGQPGQPGEKGLPGIPGKAGRQGAPGSPGQDGLPGFPGMKGESGYPGQDGLPGRDGLPGVPGQKGDLGQSGQPGLSGAPGLDGQPGVPGIRGDKGQGGLPGIPGDRGMDGYPGQKGENGYPGQPGLPGLGGEKGFAGTPGFPGLKGSPGYPGQDGLPGIPGLKGDSGFPGQPGQEGLPGLSGEKGMGGLPGMPGQPGQSIAGPVGPPGAPGLQGKDGFPGLPGQKGESGLSGLPGAPGLKGESGMPGFPGAKGDLGANGIPGKRGEDGLPGVPGRDGQPGIPGLKGEVGGAGLPGQPGFPGIPGLKGEGGLPGFPGAKGEAGFPGTPGVPGYAGEKGDGGLPGLPGRDGLPGADGPVGPPGPSGPQNLVEPGEKGLPGLPGAPGLRGEKGMPGLDGPPGNDGPPGLPGQRGNDGYPGAPGLSGEKGMGGLPGFPGLDGQPGGPGAPGLPGAPGAAGPAYRDGFVLVKHSQTTEVPRCPEGQTKLWDGYSLLYIEGNEKSHNQDLGHAGSCLQRFSTMPFLFCDFNNVCNYASRNEKSYWLSTSEAIPMMPVNEREIEPYISRCAVCEAPANTIAVHSQTIQIPNCPAGWSSLWIGYSFAMHTGAGAEGGGQSPSSPGSCLEDFRATPFIECNGARGSCHYFANKFSFWLTTIDNDSEFKVPESQTLKSGNLRTRVSRCQVCVKSTDGRH", "output": "Collagen type IV is specific for basement membranes (Probable). Together with fbl-1 and downstream of metalloprotease mig-17, recruits nidogen nid-1 to the gonad basement membrane thereby probably inducing basement membrane remodeling required for the directional migration of distal tip cells . Required to restrict presynaptic growth at the neuromuscular junctions in late larval stage and in adult motor neurons . Vital for embryonic development ."}]}
+{"id": "function_test_150", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEQTQTAEGTDLLIGDEKTNDLPFVQLFLEEIGCTQYLDSFIQCNLVTEEEIKYLDKDILIALGVNKIGDRLKILRKSKSFQRDKRIEQVNRLKNLMEKVSSLSTATLSMNSELIPEKHCVIFILNDGSAKKVNVNGCFNADSIKKRLIRRLPHELLATNSNGEVTKMVQDYDVFVLDYTKNVLHLLYDVELVTICHANDRVEKNRLIFVSKDQTPSDKAISTSKKLYLRTLSALSQVGPSSSNLLAQNKGISHNNAEGKLRIDNTEKDRIRQIFNQRPPSEFISTNLAGYFPHTDMKRLQKTMRESFRHSARLSIAQRRPLSAESNNIGDILLKHSNAVDMALLQGLDQTRLSSKLDTTKIPKLAHKRPEDNDAISNQLELLSVESGEEEDHDFFGEDSDIVSLPTKIATPKNWLKGACIGSGSFGSVYLGMNAHTGELMAVKQVEIKNNNIGVPTDNNKQANSDENNEQEEQQEKIEDVGAVSHPKTNQNIHRKMVDALQHEMNLLKELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNYGPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNKRASLQGSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGTNTTPEIPSWATSEGKNFLRKAFELDYQYRPSALELLQHPWLDAHII", "output": "Serine/threonine protein kinase required for cell-type-specific transcription and signal transduction in yeast. It is thought that it phosphorylates the STE7 protein kinase which itself, phosphorylates the FUS3 and or KSS1 kinases."}]}
+{"id": "function_test_151", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPTPSASSPQPKGFRRAVSEQDTKQAEAVTSPRFIGRRQSLIEDARKEREAAAAAAAAAVASAEPGNPLEAVVFEERDGNAVLNLLFSLRGTKPSSLSRALKVFETFEAKIHHLETRPAQRPLAGSPHLEYFVRFEVPSGDLAALLSSVRRVSDDVRSAREDKVPWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQAYRQRRKLIAEIAFQYKQGEPIPHVEYTKEEIATWKEVYATLKGLYATHACREHLEAFQLLERYCGYREDSIPQLEDVSHFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTVYWFTVEFGLCKQNGELKAYGAGLLSSYGELLHSLSEEPEVRAFDPDTAAVQPYQDQTYQPVYFVSESFSDAKDKLRNYASRIQRPFSVKFDPYTLAIDVLDSPHTIRRSLEGVQDELHTLTQALSAIS", "output": "Catalyzes the conversion of L-tyrosine to L-dihydroxyphenylalanine (L-Dopa), the rate-limiting step in the biosynthesis of cathecolamines, dopamine, noradrenaline, and adrenaline. Uses tetrahydrobiopterin and molecular oxygen to convert tyrosine to L-Dopa (By similarity). In addition to tyrosine, is able to catalyze the hydroxylation of phenylalanine and tryptophan with lower specificity (By similarity). Positively regulates the regression of retinal hyaloid vessels during postnatal development."}]}
+{"id": "function_test_152", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MFKSVAKLGKSPIFYLNSQRLIHIKTLTTPNENALKFLSTDGEMLQTRGSKSIVIKNTDENLINHSKLAQQIFLQCPGVESLMIGDDFLTINKDRMVHWNSIKPEIIDLLTKQLAYGEDVISKEFHAVQEEEGEGGYKINMPKFELTEEDEEVSELIEELIDTRIRPAILEDGGDIDYRGWDPKTGTVYLRLQGACTSCSSSEVTLKYGIESMLKHYVDEVKEVIQIMDPEQEIALKEFDKLEKKLESSKNTSHEK", "output": "Involved in iron homeostasis within the mitochondrion where it is involved in the assembly of iron-sulfur proteins . Together with BOL3, required during the last step of iron-sulfur protein assembly when the iron-sulfur cluster is inserted into the target protein . Required for protecting iron sulfur clusters from oxidative damage ."}]}
+{"id": "function_test_153", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKPAMETAAEENTEQSQERKVNSRAEMEIGRYHWMYPGSKNHQYRPVPNLGDRAGPLSSPGCFECCIKCLGGVPYASLVATILCFSGVALFCGCGHVALAGTVAILEQHFSTNTSDHALLSEVIQLMQYVIYGIASFFFLYGIILLAEGFYTTSAVKELHGEFKTTACGRCISGMFVFLTYVLGVAWLGVFGFSAVPVFMFYNIWSTCEVIKSPQSNGTSGVEQICVDVRQYGIIPWNAFPGKICGSALENICNTNEFYMSYHLFIVACAGAGATVIALIHFLMILSSNWAYLKDASKMQAYQDIKAKEEQELQDIQSRSKEQLNSYT", "output": "May be involved in neural development. Involved in regulation of osteoblast function and bone formation. Involved in matrix vesicle release by osteoblasts; this function seems to involve maintenance of the actin cytoskeleton. May be involved in cellular trafficking of SERT and thereby in regulation of serotonin uptake."}]}
+{"id": "function_test_154", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKLSALLALSASTAVLAAPAVHHSDNHHHNDKRAVVTVTQYVNADGAVVIPAATTATSAAADGKVESVAAATTTLSSTAAAATTSAAASSSSSSSSSSSSSSSVGSGDFEDGTISCSDFPSGQGAVSLDWLGLGGWASIMDMNGNTATSCQDGYYCSYACSPGYAKTQWPSEQPSDGRSVGGLYCKNGKLYRSNTDTNSLCVEGQGSAQAVNKVSGSIAICGTDYPGSENMVVPTVVGAGSSQPINVIKEDSYYQWQGKKTSAQYYVNNAGVSVEDGCIWGTEGSGVGNWAPVVLGAGYTDGITYLSIIPNPNNKEAPNFNIKIVATDGSTVNGACSYENGVYSGSGSDGCTVSVTSGSANFVFY", "output": "Involved in aging, oxidative stress response, and in the regulation of mitochondrial biogenesis. Inactivation of UTH1 increases life span, leads to higher resistance to heat stress and against hydrogen peroxide, and increases sensitivity to the superoxide radical-generating drug paraquat and to copper. Also required for the selective autophagic degradation of mitochondria (mitophagy) in response to nitrogen starvation. Involved in the remodeling of the cell wall during the various phases of yeast culture development and under various environmental conditions and plays a role in septation. Involved in cell sensitivity to boric acid."}]}
+{"id": "function_test_155", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTSAATVTASFNDTFSVSDNVAVIVPETDTQVTYRDLSHMVGHFQTMFTNPNSPLYGAVFRQDTVAISMRNGLEFIVAFLGATMDAKIGAPLNPNYKEKEFNFYLNDLKSKAICVPKGTTKLQSSEILKSASTFGCFIVELAFDATRFRVEYDIYSPEDNYKRVIYRSLNNAKFVNTNPVKFPGFARSSDVALILHTSGTTSTPKTVPLLHLNIVRSTLNIANTYKLTPLDRSYVVMPLFHVHGLIGVLLSTFRTQGSVVVPDGFHPKLFWDQFVKYNCNWFSCVPTISMIMLNMPKPNPFPHIRFIRSCSSALAPATFHKLEKEFNAPVLEAYAMTEASHQMTSNNLPPGKRKPGTVGQPQGVTVVILDDNDNVLPPGKVGEVSIRGENVTLGYANNPKANKENFTKRENYFRTGDQGYFDPEGFLVLTGRIKELINRGGEKISPIELDGIMLSHPKIDEAVAFGVPDDMYGQVVQAAIVLKKGEKMTYEELVNFLKKHLASFKIPTKVYFVDKLPKTATGKIQRRVIAETFAKSSRNKSKL", "output": "Catalyzes the first step in a degradation pathway of oxalate to CO(2) to protect the cell against the harmful effects of oxalate derived from endogenous processes or an environmental sources."}]}
+{"id": "function_test_156", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MANDLVQARDNSQVFGVARIYASFNDTFVHVTDLSGKETIARVTGGMKVKADRDESSPYAAMLAAQDVAAKCKEVGITAVHVKIRATGGTRTKTPGPGGQAALRALARSGLRIGRIEDVTPVPSDSTRKKGGRRGRRL", "output": "Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel . uS11 is involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly ."}]}
+{"id": "function_test_157", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGLVDGYDTSSDSDLNFDEGKSVHEKKNGNLHEDTSYEPSSNNIHKRKSHFTKSELKRRRKTRKGDGPWGSWSSSDDETSQASETQKEDQDIFVHALAEDNLDSEQIEVEEVSHFYGKSEKDYQGRGYLYPPNDVDVDLREERISFRCYLPKKVIRNYPGHPEGTTALKFLPKTGHLILSGGNDHTIKIWDFYHDYECLRDFQGHNKPIKALRFTEDCQSFLSSSFDRSVKIWDTETGKVKTRLHLNSTPADVESRPTNPHEFIVGLSNSKILHYDDRVSENQGLVQTYDHHLSSILALKYFPDGSKFISSSEDKTVRIWENQINVPIKQISDTAQHSMPFLNVHPSQNYFCAQSMDNRIYSFSLKPKYKRHPKKIFKGHSSAGYGISLAFSGDGRYICSGDSKSRLFTWDWNTSRLLNNIKIPGNKPITQVDWHPQETSKVICSGAAGKIYVCD", "output": "May function in the second step of pre-mRNA splicing. Regulatory protein involved in replication and mitotic spindle formation and/or maintenance. Required for initiation and completion of S-phase and for initiation and completion of DNA replication. Might be required for the maintenance of microtubules. Essential only at elevated temperatures."}]}
+{"id": "function_test_158", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKLSRALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSAIAMAPATVHAGPGDTATGKPGTPKGAGMTGQGGLARSSRNEYMRSGLYSTFTIQSLQPQPQPPIPPRPASVLPNTTPAGVPAPASGSRSTSPNPLEACLEAEEAGLPLQVILTPPEAPNQKSEELSLDPSFGHPQPPEVKVEGPKEELEAARAGGFSSEAVKAEPEVSASEGLLARLPAILTENTAQVCGLSTSTTEITQPQKGRKPRDLELPLSPSLLGGQGPERTPGSGTSSGLQAPGPALTPSLLPTHTLTPVLLTPSSLPPSIHFWSTLSPIAPRSPAKLSFQFPSSGSAQVHIPSISVDGLSTPVVLSPGPQKP", "output": "Transcription factor that binds to purine-rich DNA sequences. Forms a ternary complex with SRF and the ETS and SRF motifs of the serum response element (SRE) on the promoter region of immediate early genes such as FOS and IER2 (By similarity). Induces target gene transcription upon JNK-signaling pathway stimulation (By similarity)."}]}
+{"id": "function_test_159", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MHWTVFLLRGIVGFLWSGWVQVGYAKGGLGDNHVHSSFIYRRLRNHERREIQREILSILGLPHRPRPFSPGKQASSAPLFMLDLYNAMASEDNPEEYLVRVSLAGEAKETRKGYPASPNGYAHRLHLPPRTPLTTQSPPLASLHDTNFLNDADMVMSFVNLVERDKDFSHQRRHYKEFRFDLTQIPHGEAVTAAEFRIYKDKGNHRFENETIKISIYQIIKEYTNRDADLFLLDTRKTQALDVGWLVFDITVTSNHWVINPQNNLGLQLCAETGDGRSINVKSAGLVGRHGPQSKQPFMVAFFKASEVLLRSVRAASKRKNQNRNKSNSHQDPSRMPSAGDYNTSEQKQACKKHELYVSFRDLGWQDWIIAPEGYAAFYCDGECSFPLNAHMNATNHAIVQTLVHLMFPDHVPKPCCAPTKLNAISVLYFDDSSNVILKKYRNMVVRSCGCH", "output": "Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including cartilage and bone formation or neurogenesis . Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2. In turn, BMPR1A propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target genes. Can also signal through non-canonical pathway such as MAPK p38 signaling cascade to promote chondrogenic differentiation (By similarity)."}]}
+{"id": "function_test_160", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGTAEDVFRKDLKIIHGYPMVYAFALGWEKIEEFQSRPCDIVIPTYPKSGTTWLSEIVDMVLNDGNVEKCKRDVITSKVPMLEQNVPGARRSGVELLKKTPSPRIIKTHLPIDLLPKSFWDNKCKMIYLARNGKDVAVSYYHFDLMNNIQPLPGTWEEYLEKFLAGNVAYGSWFDHVKSWWEKREGHPILFLYYEDLKKNPKKEIKKIANFLDKTLDEHTLERIVHHTSFEVMKDNPLVNYTHLPTEIMDHSKSPFMRKGVVGDWKNYFTMTQSEKFDAIYKKKLSGTTLEFCTDIQSA", "output": "Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of dopamine, small phenols such as 1-naphthol and p-nitrophenol and thyroid hormones, including 3,3'-diiodothyronine, triidothyronine (T3) and reverse triiodothyronine (rT3) . May play a role in gut microbiota-host metabolic interaction. O-sulfonates 4-ethylphenol (4-EP), a dietary tyrosine-derived metabolite produced by gut bacteria. The product 4-EPS crosses the blood-brain barrier and may negatively regulate oligodendrocyte maturation and myelination, affecting the functional connectivity of different brain regions associated with the limbic system (By similarity)."}]}
+{"id": "function_test_161", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKVLDLLTVLSASSLLSTFAAAESTATADSTTAASSTASCNPLKTTGCTPDTALATSFSEDFSSSSKWFTDLKHAGEIKYGSDGLSMTLAKRYDNPSLKSNFYIMYGKLEVILKAANGTGIVSSFYLQSDDLDEIDIEWVGGDNTQFQSNFFSKGDTTTYDRGEFHGVDTPTDKFHNYTLDWAMDKTTWYLDGESVRVLSNTSSEGYPQSPMYLMMGIWAGGDPDNAAGTIEWAGGETNYNDAPFTMYIEKVIVTDYSTGKKYTYGDQSGSWESIEADGGSIYGRYDQAQEDFAVLANGGSISSSSTSSSTVSSSASSTVSSSVSSTVSSSASSTVSSSVSSTVSSSSSVSSSSSTSPSSSTATSSKTLASSSVTTSSSISSFEKQSSSSSKKTVASSSTSESIISSTKTPATVSSTTRSTVAPTTQQSSVSSDSPVQDKGGVATSSNDVTSSTTQISSKYTSTIQSSSSEASSTNSVQISNGADLAQSLPREGKLFSVLVALLALL", "output": "Probable glycosidase that plays a role in cell wall architecture. Required for the transfer of chitin to 1,6-beta-glucan in the cell wall."}]}
+{"id": "function_test_162", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRRLSSWRKMATAEKQKHDGRVKIGHYILGDTLGVGTFGKVKVGKHELTGHKVAVKILNRQKIRSLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTFSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSISNYRSCQRSDSDAEAQGKPSEVSLTSSVTSLDSSPVDVAPRPGSHTIEFFEMCANLIKILAQ", "output": "Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism . In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation (By similarity). AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators (By similarity). Regulates lipid synthesis by phosphorylating and inactivating lipid metabolic enzymes such as ACACA, ACACB, GYS1, HMGCR and LIPE; regulates fatty acid and cholesterol synthesis by phosphorylating acetyl-CoA carboxylase (ACACA and ACACB) and hormone-sensitive lipase (LIPE) enzymes, respectively . Promotes lipolysis of lipid droplets by mediating phosphorylation of isoform 1 of CHKA (CHKalpha2) (By similarity). Regulates insulin-signaling and glycolysis by phosphorylating IRS1, PFKFB2 and PFKFB3 . AMPK stimulates glucose uptake in muscle by increasing the translocation of the glucose transporter SLC2A4/GLUT4 to the plasma membrane, possibly by mediating phosphorylation of TBC1D4/AS160 (By similarity). Regulates transcription and chromatin structure by phosphorylating transcription regulators involved in energy metabolism such as CRTC2/TORC2, FOXO3, histone H2B, HDAC5, MEF2C, MLXIPL/ChREBP, EP300, HNF4A, p53/TP53, SREBF1, SREBF2 and PPARGC1A . Acts as a key regulator of glucose homeostasis in liver by phosphorylating CRTC2/TORC2, leading to CRTC2/TORC2 sequestration in the cytoplasm (By similarity). In response to stress, phosphorylates 'Ser-36' of histone H2B (H2BS36ph), leading to promote transcription (By similarity). Acts as a key regulator of cell growth and proliferation by phosphorylating TSC2, RPTOR and ATG1/ULK1: in response to nutrient limitation, negatively regulates the mTORC1 complex by phosphorylating RPTOR component of the mTORC1 complex and by phosphorylating and activating TSC2 (By similarity). In response to nutrient limitation, promotes autophagy by phosphorylating and activating ATG1/ULK1 (By similarity). In that process also activates WDR45/WIPI4. Phosphorylates CASP6, thereby preventing its autoprocessing and subsequent activation (By similarity). In response to nutrient limitation, phosphorylates transcription factor FOXO3 promoting FOXO3 mitochondrial import (By similarity). Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin (By similarity). AMPK also acts as a regulator of circadian rhythm by mediating phosphorylation of CRY1, leading to destabilize it (By similarity). May regulate the Wnt signaling pathway by phosphorylating CTNNB1, leading to stabilize it (By similarity). Also has tau-protein kinase activity: in response to amyloid beta A4 protein (APP) exposure, activated by CAMKK2, leading to phosphorylation of MAPT/TAU; however the relevance of such data remains unclear in vivo . Also phosphorylates CFTR, EEF2K, KLC1, NOS3 and SLC12A1 ."}]}
+{"id": "function_test_163", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGDMGDPPKKKRLISLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRLYGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADHDVVERASLGAGDPLSPLHPARPLQMAAEPISARQPALRPHVHKQPEKTTRVRTVLNEKQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIMMKQLQQQQPNDKTNIQGMTGTPMVAASPERHDGGLQANPVEVQSYQPPWKVLSDFALQSDIDQPAFQQLVNFSEGGPGSNSTGSEVASMSSQLPDTPNSMVASPIEA", "output": "DNA-binding transcriptional activator . Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA-3' in promoter of target genes . Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation . Cooperates with the transcription factor POU4F2 to achieve maximal levels of expression of RGC target genes and RGC fate specification in the developing retina . Involved in the specification of motor neurons in cooperation with LHX3 and LDB1 . Binds to insulin gene enhancer sequences (By similarity). Essential for heart development. Marker of one progenitor cell population that give rise to the outflow tract, right ventricle, a subset of left ventricular cells, and a large number of atrial cells as well, its function is required for these progenitors to contribute to the heart. Controls the expression of FGF and BMP growth factors in this cell population and is required for proliferation and survival of cells within pharyngeal foregut endoderm and adjacent splanchnic mesoderm as well as for migration of cardiac progenitors into the heart ."}]}
+{"id": "function_test_164", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRPVFVGNFEYETRQSDLERLFDKYGRVDRVDMKSGYAFVYFEDERDAEDAIRKLDNFPFGYEKRRLSVEWAKGERGRPRGDAKAPSNLKPTKTLFVINFDPIRTKEHDIEKHFEPYGKVTNVRIRRNFSFVQFETQEDATKALEATQRSKILDRVVSVEYALKDDDERDDRNGGRSPRRSLSPVYRRRPSPDYGRRPSPGQGRRPSPDYGRARSPEYDRYKGPAAYERRRSPDYGRRSSDYGRQRSPGYDRYRSRSPVPRGRP", "output": "Required for constitutive and alternative pre-mRNA splicing."}]}
+{"id": "function_test_165", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLPVLYTGLAGLLLLPLLLTCCCPYLLQDVRFFLQLANMARQVRSYRQRRPVRTILHVFLEQARKTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALFMGNEPAYVWLWLGLLKLGCPMACLNYNIRAKSLLHCFQCCGAKVLLASPELHEAVEEVLPTLKKEGVSVFYVSRTSNTNGVDTVLDKVDGVSADPIPESWRSEVTFTTPAVYIYTSGTTGLPKAATINHHRLWYGTSLALRSGIKAHDVIYTTMPLYHSAALMIGLHGCIVVGATFALRSKFSASQFWDDCRKYNATVIQYIGELLRYLCNTPQKPNDRDHKVKIALGNGLRGDVWREFIKRFGDIHIYEFYASTEGNIGFMNYPRKIGAVGRENYLQKKVVRHELIKYDVEKDEPVRDANGYCIKVPKGEVGLLICKITELTPFFGYAGGKTQTEKKKLRDVFKKGDVYFNSGDLLMIDRENFIYFHDRVGDTFRWKGENVATTEVADIVGLVDFVEEVNVYGVPVPGHEGRIGMASIKMKENYEFNGKKLFQHISEYLPSYSRPRFLRIQDTIEITGTFKHRKVTLMEEGFNPSVIKDTLYFMDDTEKTYVPMTEDIYNAIIDKTLKL", "output": "Mediates the import of long-chain fatty acids (LCFA) into the cell by facilitating their transport across cell membranes, playing an important role in hepatic fatty acid uptake (By similarity). Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates, which prevents fatty acid efflux from cells and might drive more fatty acid uptake . Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis . Can also activate branched-chain fatty acids such as phytanic acid and pristanic acid (By similarity). May contribute to the synthesis of sphingosine-1-phosphate (By similarity). Does not activate C24 bile acids, cholate and chenodeoxycholate. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. However, it is not critical for THCA activation and bile synthesis in vivo (By similarity)."}]}
+{"id": "function_test_166", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEPAGPAPGRLGPLLLCLLLSASCFCTGATGKELKVTQPEKSVSVAAGDSTVLNCTLTSLLPVGPIRWYRGVGPSRLLIYSFAGEYVPRIRNVSDTTKRNNMDFSIRISNVTPADAGIYYCVKFQKGSSEPDTEIQSGGGTEVYVLAKPSPPEVSGPADRGIPDQKVNFTCKSHGFSPRNITLKWFKDGQELHPLETTVNPSGKNVSYNISSTVRVVLNSMDVNSKVICEVAHITLDRSPLRGIANLSNFIRVSPTVKVTQQSPTSMNQVNLTCRAERFYPEDLQLIWLENGNVSRNDTPKNLTKNTDGTYNYTSLFLVNSSAHREDVVFTCQVKHDQQPAITRNHTVLGFAHSSDQGSMQTFPDNNATHNWNVFIGVGVACALLVVLLMAALYLLRIKQKKAKGSTSSTRLHEPEKNAREITQVQSLIQDTNDINDITYADLNLPKEKKPAPRAPEPNNHTEYASIETGKVPRPEDTLTYADLDMVHLSRAQPAPKPEPSFSEYASVQVQRK", "output": "Immunoglobulin-like cell surface receptor for CD47 . Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells (By similarity). Plays a role in antiviral immunity and limits new world arenavirus infection by decreasing virus internalization . Receptor for THBS1 (By similarity). Interaction with THBS1 stimulates phosphorylation of SIRPA (By similarity). In response to THBS1, involved in ROS signaling in non-phagocytic cells, stimulating NADPH oxidase-derived ROS production (By similarity)."}]}
+{"id": "function_test_167", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAKKRIAVIGAGASGLTCIKCCLEEGLEPVCFERSGDIGGLWRFQEAPEEGRASIYQSVVINTSKEMMCFSDYPIPDHYPNYMHNSQVLEYFRMYAKEFDLLKYIQFKTTVCSVKKQPDFSTSGQWQVVTECEGKQQVDVFDGVLVCTGHHTDAHLPLESFPGIEKFKGKYFHSRDYKNPVEFTGKRVIVIGIGNSGGDLAVEISHTAKQVFLSTRRGAWILNRVGKHGYPIDLLLSSRIMYYLSRICGPSLKNNYMEKQMNQRFDHEMFGLKPKHRALSQHPTVNDDLPNRIIAGLVKVKGNVKEFTETAAVFEDGSREDGIDVVIFATGYSFAFPFLEDSVKVVKNKVSLYKKVFPPNLEKPTLAIIGLIQPLGAIMPISELQGRWATQVFKGLKKLPSQSEMMAEINKAREEMAKRYVDSQRHTIQGDYIDTMEEIADLVGVRPNILPLVFTDPRLALRLLLGPCTPVQYRLQGPGKWAGARKTILTTEDRVRKPLMTRVVERDSSGGSLVTVRVLMLAVAFFAVILAYF", "output": "Acts as Baeyer-Villiger monooxygenase on a broad range of substrates. Catalyzes the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Active on diverse carbonyl compounds, whereas soft nucleophiles are mostly non- or poorly reactive. In contrast with other forms of FMO it is non- or poorly active on 'classical' substrates such as drugs, pesticides, and dietary components containing soft nucleophilic heteroatoms. Able to oxidize drug molecules bearing a carbonyl group on an aliphatic chain, such as nabumetone and pentoxifylline. Also, in the absence of substrates, shows slow but yet significant NADPH oxidase activity (By similarity). Acts as a positive modulator of cholesterol biosynthesis as well as glucose homeostasis, promoting metabolic aging via pleiotropic effects ."}]}
+{"id": "function_test_168", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSSIKIECVLRENYRCGESPVWEEASKCLLFVDIPSKTVCRWDSISNRVQRVGVDAPVSSVALRQSGGYVATIGTKFCALNWEDQSVFILAMVDEDKKNNRFNDGKVDPAGRYFAGTMAEETAPAVLERHQGSLYSLFPDHSVKKYFDQVDISNGLDWSLDHKIFYYIDSLSYTVDAFDYDLPTGQISNRRTVYKMEKDEQIPDGMCIDVEGKLWVACYNGGRVIRLDPETGKRLQTVKLPVDKTTSCCFGGKDYSEMYVTCARDGMSAEGLLRQPDAGNIFKITGLGVKGIAPYSYAG", "output": "Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Catalyzes a key step in ascorbic acid (vitamin C) biosynthesis. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities."}]}
+{"id": "function_test_169", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKKVRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAVEAGIEDIIIVTGKSKRAIEDHFDYSPELERNLEEKGKTELLEKVKKASNLADIHYIRQKEPKGLGHAVWCARNFIGDEPFAVLLGDDIVQAETPGLRQLMDEYEKTLSSIIGVQQVPEEETHRYGIIDPLTSEGRRYQVKNFVEKPPKGTAPSNLAILGRYVFTPEIFMYLEEQQVGAGGEIQLTDAIQKLNEIQRVFAYDFEGKRYDVGEKLGFITTTLEFAMQDKELRDQLVPFMEGLLNKEEI", "output": "Catalyzes the formation of UDP-glucose from glucose-1-phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. the predominant glycolipid found in B.subtilis membrane, which is also used as a membrane anchor for lipoteichoic acid (LTA). Has a role in the biosynthesis of all phosphate-containing envelope polymers, since UDP-glucose serves as a glucosyl donor not only for the biosynthesis of LTA but also for wall teichoic acids (WTAs). Is required for biofilm formation. This is likely due to another role of UDP-glucose, which might also act as a metabolic signal regulating biofilm formation or may be involved in some unknown biosynthetic pathway essential for biofilm formation, e.g. the synthesis of an exopolysaccharide."}]}
+{"id": "function_test_170", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSLCSSFNVFASYSPKPKTIFKDSKFISQFQVKSSPLASTFHTNESSTSLKYKRARLKPISSLDSGISEIATSPSFRNKSPKDINVLVVGSTGYIGRFVVKEMIKRGFNVIAVAREKSGIRGKNDKEETLKQLQGANVCFSDVTELDVLEKSIENLGFGVDVVVSCLASRNGGIKDSWKIDYEATKNSLVAGKKFGAKHFVLLSAICVQKPLLEFQRAKLKFEAELMDLAEQQDSSFTYSIVRPTAFFKSLGGQVEIVKDGKPYVMFGDGKLCACKPISEQDLAAFIADCVLEENKINQVLPIGGPGKALTPLEQGEILFKILGREPKFLKVPIEIMDFVIGVLDSIAKIFPSVGEAAEFGKIGRYYAAESMLILDPETGEYSEEKTPSYGKDTLEDFFAKVIREGMAGQELGEQFF", "output": "Catalyzes the conversion of divinyl chlorophyllide to monovinyl chlorophyllide. Reduces the 8-vinyl group of the tetrapyrrole to an ethyl group using NADPH as the reductant. The best substrate is (3,8-divinyl)-chlorophyllide a (DV-Chlidea). Very low activity with (3,8-divinyl)-protochlorophyllide a (DV-Pchlidea) and (3,8-divinyl)-magnesium-protoporphyrin IX monomethyl ester (DV-MPE). No activity with (3,8-divinyl)-chlorophyllide b (DV-Chlideb), (3,8-divinyl)-magnesium-protoporphyrin IX (DV-Mg-Proto) and either (3,8-divinyl)-chlorophyll a (DV-Chla) or b (DV-Chlb)."}]}
+{"id": "function_test_171", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDFSNTYRNYGEVVDFPEDFLSDYVPTVKSEPEPAAIAPSVCEPPISTTRNYGTDFGRASSMCGSSSSSSSSSYSSGSSPNYLTENGGDTEEPRFEELVSRKMSFDSENVAQVSNQMDYARDTYADSRIPFASIDSNDALLPYPVNNYVAALPVPVPAKKSRGRTAPRTPKSLETSKPGRGVKRPASKEIDAKDLGIGDLSAHMNRQIGDDEELDTQLIAHRILDELKEQCIPQASLAVKVLGRSQGTLSDLLRKPKPWGIMKNGRGTFQRMANWLDLDPVVRRALCFMKKEDVARITGMAEPTPAKRARQTTPSDERIRRFTFTQTQLDSLHTVFQQQDRPNREMQQALSATLKLNRSTVGNFFMNARRRLPKAAPVSQNLVAEHAIDHNQPGPSHHY", "output": "Transcriptional regulator which is involved in the sex determination and X chromosome dosage compensation pathways . Directly binds to 5'-ATTGAT-3' sites in the promoter of sex-determining factor xol-1 to negatively regulate its expression and promote hermaphrodite development . Associates with condensed DNA during mitosis ."}]}
+{"id": "function_test_172", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAVPFYLPEGGADDVASSSSGASGNSSPHNHPLPSSASSSVSSSGVSSASASSASSSSSASSDGASSAASQSPNTTTSSATQTPMQSPLPTDQVLYALYEWVRMYQSQQSAPQIFQYPPPSPSCNFTGGDVFFPHGHPNPNSNPHPRTPRTSVSFSSGEEYNFFRQQQPQPHPSYPAPSTPQPMPPQSAPPMHCSHSYPQQSAHMMPHHSAPFGMGGTYYAGYTPPPTPNTASAGTSSSSAAFGWHGHPHSPFTSTSTPLSAPVAPKMRLQRSQSDAARRKRLTSTGEDEREYQSDHEATWDEFGDRYDNFTAGRERLQEFNGRIPPRKKKSSNSHSSSSNNPVCHTDSQPGGTSQAESGAIHGHISQQRQVERERQKAKAEKKKPQSFTWPTVVTVFVLAMGCGFFAAR", "output": "Activator of apoptosis, with grim and rpr, that acts on the effector Dredd . Seems to act genetically upstream of baculoviral anti-apoptotic p35 . Blocks Diap2 from binding and inactivating the effector caspase Drice . Might regulate apoptosis downstream of Clbn/NEMF ."}]}
+{"id": "function_test_173", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAGPSWGLPRLDGFILTERLGSGTYATVYKAYAKKDTREVVAIKCVAKKSLNKASVENLLTEIEILKGIRHPHIVQLKDFQWDNDNIYLIMEFCAGGDLSRFIHTRRILPEKVARVFMQQLASALQFLHERNISHLDLKPQNILLSSLEKPHLKLADFGFAQHMSPWDEKHVLRGSPLYMAPEMVCRRQYDARVDLWSVGVILYEALFGQPPFASRSFSELEEKIRSNRVIELPLRPQLSLDCRDLLQRLLERDPARRISFKDFFAHPWVDLEHMPSGESLAQARALVVEAVKKDQEGDAAAALSLYCKALDFFVPALHYEVDAQRKEAIKAKVGQYVSRAEELKAIVSSSNQALLRQGTTVQELLREMARDKPRLLAALEVASAALAKEEEAGKEQDALDLYQHSLGELLVLLAAEAPGRRRELLHTEVQNLMARAEYLKEQIKIRESHWEAESLDKEGLSESVRSSCTLQ", "output": "Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy (By similarity)."}]}
+{"id": "function_test_174", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MVAMIMASRFNREAKLASQILSTLLGNRSCYTSMAATSSSALLLNPLTSSSSSSTLRRFRCSPEISSLSFSSASDFSLAMKRQSRSFADGSERDPSVVCEAVKRETGPDGLNIADNVSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGYSMVTDAEQKGFISPGKSVLVEPTSGNTGIGLAFIAASRGYRLILTMPASMSMERRVLLKAFGAELVLTDPAKGMTGAVQKAEEILKNTPDAYMLQQFDNPANPKIHYETTGPEIWDDTKGKVDIFVAGIGTGGTITGVGRFIKEKNPKTQVIGVEPTESDILSGGKPGPHKIQGIGAGFIPKNLDQKIMDEVIAISSEEAIETAKQLALKEGLMVGISSGAAAAAAIKVAKRPENAGKLIAVVFPSFGERYLSTPLFQSIREEVEKMQPEV", "output": "Acts as a cysteine synthase. Plays a role in the sulfide detoxification in mitochondria."}]}
+{"id": "function_test_175", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTHLSLADPVREPLFSGEAGRQTAMAKDILAEAGLHFDELNKLRVLDPEVSQQTIELKEECKDFVDKIGQFQKIVGGLIELVDQLAKEAENEKMKAIGARNLLKSIAKQREAQQQQLQALIAEKKMQLERYRVEYEALCKVEAEQNEFIDQFIFQK", "output": "Part of intraflagellar transport (IFT) particles involved in ciliary process assembly. May play a role in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium. Regulates the platelet-derived growth factor receptor-alpha (PDGFRA) signaling pathway. Required for protein stability of E3 ubiquitin ligases CBL and CBLB that mediate ubiquitination and internalization of PDGFRA for proper feedback inhibition of PDGFRA signaling. Essential for male fertility. Plays an important role in spermatogenesis, particularly spermiogenesis, when germ cells form flagella. May play a role in the transport of flagellar proteins ODF2 and SPAG16 to build sperm flagella and in the removal of redundant sperm cytoplasm. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment."}]}
+{"id": "function_test_176", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLRAGSVVTCIACKGLLPSRMGVKFRVPLQKLHPLSRAIHHRYSANNNPQRPPHCSAARHYTSLSRLPMRPPKSRSGGHGYQQHRTFWVARLAARLLKLRYILLGSAVGGGYTAKKTYDEWKEMLPDMSEYTWIVPDFVWELSENIDLDKLASALPELEEIAKLLPDMEKIGENFTFLKSLLSSETTGESALRAPDVPPASAAMADSGDKQFKKSSDKEKVDQLQEELLRTQLKYQRMLERLEKENKELRKVVLQKDDKGIHQRKVKKSLIDMYSEVLDILSDYDSNYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVAMFKDSSREFDLGKEEDLAALRHEIELRMRKSVKEGQTVSPETISLSVKGPGIQRMVLVDLPGVISTVTTGMAADTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPQGKRTIFVLTKVDLAEKNLASPSRIQQIVEGKLFPMKALGYFAVVTGKGSPNESIDSIKDYEEDFFQNSRLLKDGMLKAHQVTTKNLSLAVSDCFWKMVRESVEQQADAFKASRFNLETEWKNNYPRLRELDRNELYEKAKNEILDEVISLSQVTPKHWESILQKKLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPHKALEVAWETLQEEFARFMAEYKGKDQDDIFDKLKEAVKDESIKRHKWNERAMDSLRVIQHNALEDRSITDKPQWDAAIQFMEETLQSRLKDTESVIADMVGPDWKQRWMSWKNRTPEQHTRNETKNELERLLKLHEDHTAYLANDEVTTVRKNLEARGVEVDPVLIKDTWHQLFRRHFLQKALLHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLGITANTLRQQLTNTEVRRLEKNVKEVLEDFGEDNEKKVQLITGRRVQLAEDLKKVREIQEKLEAFIEALHKEK", "output": "Dynamin-related GTPase that is essential for normal mitochondrial morphology by regulating the equilibrium between mitochondrial fusion and mitochondrial fission. Binds lipid membranes enriched in negatively charged phospholipids, such as cardiolipin, and promotes membrane tubulation. The intrinsic GTPase activity is low, and is strongly increased by interaction with lipid membranes (By similarity). Plays a role in remodeling cristae and the release of cytochrome c during apoptosis (By similarity).; "}]}
+{"id": "function_test_177", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSIFCLAAYFWLTMVGGVMADNPERYSANLSSHMEDFTPFPGTEINFLGTTHRPPNLALPSNGSMHGYCPQQTKITTAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLITAIEIVSIWILSFILAIPEAIGFVMVPFEYKGELHRTCMLNATSKFMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFPLHLSRILKKTVYDEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFKNCFQSCLCCCCHQSKSLMTSVPMNGTSIQWKNQEQNNHNTERSSHKDSMN", "output": "Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3 (By similarity)."}]}
+{"id": "function_test_178", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAIKNILALVVLLSVVGVSVAIPQLLDLDYYRSKCPKAEEIVRGVTVQYVSRQKTLAAKLLRMHFHDCFVRGCDGSVLLKSAKNDAERDAVPNLTLKGYEVVDAAKTALERKCPNLISCADVLALVARDAVAVIGGPWWPVPLGRRDGRISKLNDALLNLPSPFADIKTLKKNFANKGLNAKDLVVLSGGHTIGISSCALVNSRLYNFTGKGDSDPSMNPSYVRELKRKCPPTDFRTSLNMDPGSALTFDTHYFKVVAQKKGLFTSDSTLLDDIETKNYVQTQAILPPVFSSFNKDFSDSMVKLGFVQILTGKNGEIRKRCAFPN", "output": "Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue."}]}
+{"id": "function_test_179", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNHKSKKRIKEAKRSARPELKDSSDWTKHEYCKSFDLSHRSVKDNVERADVQRLSPEEFIQRFEKPYKPVVLLNVEDSWPAREKWTLERLKRKYRNQKFKCGEDNDGYSVKMKMKYYVEYLESTHDDSPLYIFDSSFGEHAKRRKLLEDYQVPLFFRDDLFQFAGEKRRPPYRWFVMGPARSGTGIHIDPLGTSAWNALVQGHKRWCLFPTHTPRELIKVTRDEGGNQQDEAITWFNVIYPRTQQSTWPDEFRPLEILQRPGETVFVPGGWWHVVLNLDTTIAVTQNFASTTNFPIVWHKTVRGRPKLSRKWYRILKQERPDIAAIADKVDLQESTGIASDSSSDSSSSSSSSSSDSDSEADSGSEGDAMTHRRKKRRTGGMMGNGDITSQDDCASKERSSSR", "output": "Dioxygenase that can both act as a arginine demethylase and a lysyl-hydroxylase. Acts as a lysyl-hydroxylase that catalyzes 5-hydroxylation on specific lysine residues of target proteins such as u2af2/u2af65 and LUC7L2. Regulates RNA splicing by mediating 5-hydroxylation of u2af2/u2af65, affecting the pre-mRNA splicing activity of u2af2/u2af65. Hydroxylates its own N-terminus, which is required for homooligomerization. In addition to peptidyl-lysine 5-dioxygenase activity, may act as an RNA hydroxylase, as suggested by its ability to bind single strand RNA. Also acts as an arginine demethylase which preferentially demethylates asymmetric dimethylation. Demethylates histone H3 at 'Arg-2' (H3R2me) and histone H4 at 'Arg-3' (H4R3me), including mono-, symmetric di- and asymmetric dimethylated forms, thereby playing a role in histone code. However, histone arginine demethylation may not constitute the primary activity in vivo. In collaboration with brd4, interacts with the positive transcription elongation factor b (P-TEFb) complex in its active form to regulate polymerase II promoter-proximal pause release for transcriptional activation of a large cohort of genes. Demethylates other arginine methylated-proteins such as esr1. Has no histone lysine demethylase activity (By similarity). Required for differentiation of multiple organs during embryogenesis. Acts as a key regulator of hematopoietic differentiation (By similarity)."}]}
+{"id": "function_test_180", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MADAASQVLLGSGLTILSQPLMYVKVLIQVGYEPLPPTIGRNIFGRQVCQLPGLFCYAQHIASIDGRRGLFTGLTPRLCSGVLGTVVHGKVLQYYQESEKPEELGSVTVQKEYSSSFDRVIKETTREMIARSAATLITHPFHVITLRSMVQFIGRESKYCGLCDSIVTIYREEGIVGFFAGLIPRLLGDIISLWLCNSLAYLINTYALDSGVSTMNEMKSYSQAVTGFFASMLTYPFVLVSNLMAVNNCGLAGGSPPYSPIYTSWIDCWCMLQKAGNMSRGNSLFFRKVPCGKTYCYDLRMLI", "output": "Protein insertase that mediates insertion of transmembrane proteins into the mitochondrial outer membrane. Catalyzes insertion of proteins with alpha-helical transmembrane regions, such as signal-anchored, tail-anchored and multi-pass membrane proteins. Does not mediate insertion of beta-barrel transmembrane proteins (By similarity). Also acts as a receptor for the truncated form of pro-apoptotic BH3-interacting domain death agonist (p15 BID) and has therefore a critical function in apoptosis . Regulates the quiescence/cycling of hematopoietic stem cells (HSCs) . Acts as a regulator of mitochondrial fusion, essential for the naive-to-primed interconversion of embryonic stem cells (ESCs) . Acts as a regulator of lipid homeostasis and has a regulatory role in adipocyte differentiation and biology ."}]}
+{"id": "function_test_181", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLSSPTVILQPYGLPVYPQTASCYPGIVQGAAAQEAGPGNGDPSLPQVYAPPPSYPPPGQAPPTPAARLPPLDFSAAHPNSEYADHHQLRVYQGPQHDGTESITASNTDDSLAPVTSDPQSLSVSVASGSGAAGGSDEEGGGKAQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFESAVEADRAREKLNGTIVEGRKIEVNNATARVVTKKPQTPLVNAAGWKINPVMGAMYAPELYTVASFPYPVPTPTLAYRGSGLRGRGRAVYNTIRSAAAAATPAAVPAYPGVVYQEGLYGAEVYGGYPATYRVAQSASAAATATYSDGYGRVYATATDPYHHSVGPTTTYGVGTMASLYRGGYNRFTPY", "output": "RNA-binding protein that regulates alternative splicing events by binding to 5'-GCAUG-3' elements. Regulates alternative splicing of tissue-specific exons."}]}
+{"id": "function_test_182", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSHSFFNLFLISLFLYNNCIAHHYTFTVREVPYTKLCSTKAILTVNSQFPGPIIKVHKGDTIYVNVQNRASENITMHWHGVEQPRNPWSDGPEYITQCPIRPGSDFLYKVIFSIEDTTVWWHAHSSWTRATVHGLIFVYPRPPQILPFPKADHEVPIILGEWWKRDVREVVEEFVRTGGAPNVSDALTINGHPGFLYPCSKSDTFHLTVEKGKTYRIRMVNAAMNLPLFFAIANHSLTVVSADGHYIKPIKATYITISPGETLDMLLHADQDPERTYYMAARAYQSGNIDFNNSTTIGILSYTSSCKAKTSSFSGYYPTLPFYNDTSAAFGFFTKIKCLFSGQVPVQISRRIITTVSINLRMCPQNSCEGPNGSRLAASMNNISFVTPSHVDILKAYYYHIKGVYGTRFPEFPPLIFNFTAENQPLFLETPRLATEVKVIEFGQVVELVIQGTSLVGGGLDHPMHLHGFSFYVVGVGFGNYNISEEDPSSRYNLYDPPYKNTMTVPRNGWIAIRFVADNPGVWFMHCHLDRHQTWGMNVVFIVKNGREPNQQILPPPDDLPPCYE", "output": "Lignin degradation and detoxification of lignin-derived products (By similarity). Involved in lignin synthesis in seed coats, in seed coat permeability, in seed germination, and in root elongation. Required for the seed coat (testa) brown pigmentation by mediating the polymerization of proanthocyanidin (tannin) from its monomer precursor epicatechin. Slightly promotes seed dormancy."}]}
+{"id": "function_test_183", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLRWLRAFVLPTAACHDAEPPTRYETLFRALDRNGDGVVDIGELQQGLQSLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEPSEIVQSLQMLGLHISEKQAELILQSIDSDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGVAGAVSRTSTAPLDRLKVMMQVHGSKSMNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKLGTFERFISGSMAGATAQTFIYPMEVLKTRLAVAKTGQYSGIYGCAKKILKHEGFGAFYKGYIPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLSCGALSSTCGQLASYPLALVRTRMQAQATVEGAPQLSMVGLFQRIVSKEGVSGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVAQK", "output": "Electroneutral antiporter that mediates the transport of adenyl nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter. By regulating the mitochondrial matrix adenyl nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenyl nucleotide-dependent metabolic pathways. In vitro, a low activity is also observed with guanyl and pyrimidine nucleotides. May play a role in protecting cells against oxidative stress-induced cell death, by buffering calcium levels in the mitochondrial matrix through the formation of calcium-phosphate precipitates."}]}
+{"id": "function_test_184", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPKRKNSGQSTDLNSRSPKTIDEALRILAPPQALLVQSQLNLTAPANPFSIQKAPGTSSDNEQRAPKRRADEEAVNAVPKNLLTTSSTFARAVIPAAPAISSANNKMAPQSVTATAKTTTNRGKVSGEGEYQLIKNEVLCSPYGNQYEVLEFLGKGTFGQVVKAWKKGTSEIVAIKILKKHPSYARQGQIEVSILSRLSNENSEEFNFVRAFECFNHKSHTCLVFEMLEQNLYDFLKQNKFMPLPLNAIRPILFQVLTALLKLKSLGLIHADLKPENIMLVDPQQQPYRVKVIDFGSASHRSKAVTNTYLQSRYYRAPEIILGLPFNESIDMWSLGCVIAELFLGWPLYPGSSEYDQIRFIIQTQGLPPTSMLESASKLHRFFKEVKSESPNHTNVGGSYYRLKTVEEYEASSSTAKSKETRKYIFNVIDDISRVCYGFESDPVEHLCDRIDRQEFVDVLKKMLVLNPDFRITPAEGLESKFVTMTHINGYNFANYVHEAHKRMEICRKPGPAMATPYRAANVATPITPVEKPPAPKLQQPMIAVLPQLNQIAATNIPPVPTQPDLTNLMHHYSQMAAATGSAATAAQFFYQPLPPAPLFQYAQLHHPFAARPPHFLSLATPSHMVPQFVPVPIMDPSMLQGQWPPGAAQQFAVLANDIMRVPAPQGINQMFASTPQTFSLPQFLSSSIPSATTAFNGNAPNIPFPEENSSWALGTAAQQQQQQAQRAQSMINGNVKVKPLAAQPKKNSPAPSVITLSSDEDSNGAGSSNSGSTTRTGAVNPVRNDTLPMGNTIKTEDILVPPTTFDGQLPNLQYFPGSHLFDPKTVAGLLPNPFLDTSHIPRAFN", "output": "Serine/threonine-protein kinase required in the somatic gonadal cells to regulate germline proliferation during larval development and in adulthood . Plays a role in the development/differentiation of gonadal distal tip cells . Required for normal lifespan in a pha-4 and mxl-2-dependent manner . Also contributes to survival following heat or oxidative stress . Prevents sumoylation and inactivation of heat shock transcription factor hsf-1 which enhances hsf-1-dependent transcriptional induction of chaperones in response to heat shock . Also required for hormetic extension of longevity in response to heat stress . Provides protection against polyglutamine aggregate formation and associated locomotory toxicity . Also contributes to longevity by promoting autophagy under nutrient stress conditions through induction of autophagosome formation and autophagy gene expression ."}]}
+{"id": "function_test_185", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNPRKKVDLKLIIVGALGVGKTSLLHQYVHKTFFEEYQTTLGASILSKIIILDDTTLKLQIWDTGGQERFRSMVSTFYKGSDGCILAFDVTDPESFEALDIWRDDVLAKIIPMEQSYPMVVLGNKIDLEDRKVSQEVVHGWCKEKDMPYFEVSAKNDINVVQAFEVLASRALLRYQGTAENHLIDSIKLSPGQPKSRCC", "output": "Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway."}]}
+{"id": "function_test_186", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAPGSVSSVSSSSFPSRDTSPSGSCGLPGADKPGPSCRRIQAGQRNPTMLHMVLEALKAREARQGTSVVAIKVYIQHKYPTVDTTRFKYLLKQALETGVRRGLLTRPAHSKAKGATGSFKLVPKPKTKKACAPKAGRGAAGAKETGSKKSGLLKKDQVGKATMEKGQKRRAYPCKAATLEMAPKKAKAKPKEVRKAPLKQDKAAGAPLTANGGQKVKRSGSRQEANAHGKTKGEKSKPLASKVQNSVASLAKRKMADMAHTVTVVQGAETVQETKVPTPSQDIGHKVQPIPRVRKAKTPENTQA", "output": "May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling."}]}
+{"id": "function_test_187", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTKLLEINHIQTLCFAKGFSPARLNVATSPFRISRRGGGGYCSNACIPYRLKFTCYATLSAVVKEQASDFSGKEAALLVDELRSNFNSGRTKSYEWRISQLQNIARMIDEKEKCITEALYQDLSKPELEAFLAEISNTKSSCMLAIKELKNWMAPETVKTSVTTFPSSAQIVSEPLGVVLVISAWNFPFLLSVEPVIGAIAAGNAVVLKPSEIAPAASSLLAKLFSEYLDNTTIRVIEGGVPETTALLDQKWDKIFFTGGARVARIIMAAAARNLTPVVLELGGKCPALVDSDVNLQVAARRIIAGKWACNSGQACIGVDYVITTKDFASKLIDALKTELETFFGQNALESKDLSRIVNSFHFKRLESMLKENGVANKIVHGGRITEDKLKISPTILLDVPEASSMMQEEIFGPLLPIITVQKIEDGFQVIRSKPKPLAAYLFTNNKELEKQFVQDVSAGGITINDTVLHVTVKDLPFGGVGESGIGAYHGKFSYETFSHKKGVLYRSFSGDADLRYPPYTPKKKMVLKALLSSNIFAAILAFFGFSKDS", "output": "Involved in oxidative stress tolerance by detoxifying reactive aldehydes derived from lipid peroxidation. Medium- to long-chain saturated aldehydes are preferred substrates, while the short-chain aldehyde propanal is a weak substrate. Can use both NAD(+) and NADP(+), but the coenzyme preference is substrate dependent."}]}
+{"id": "function_test_188", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MQGDSSPSPTTTSSPLIRPINRNVIHRICSGQVILDLSSAVKELVENSLDAGATSIEINLRDYGEDYFQVIDNGCGISPTNFKVLALKHHTSKLEDFTDLLNLTTYGFRGEALSSLCALGNLTVETRTKNEPVATLLTFDHSGLLTAEKKTARQIGTTVTVRKLFSNLPVRSKEFKRNIRKEYGKLVSLLNAYALIAKGVRFVCSNTTGKNPKSVVLNTQGRGSLKDNIITVFGISTFTSLQPVSICVSEDCRVEGFLSKPGQGTGRNLADRQYFFINGRPVDMPKVSKLVNELYKDTSSRKYPVTILDFIVPGGACDLNVTPDKRKVFFSDETSVIGSLREGLNEIYSSSNASYIVNRFEENSEQPDKAGVSSFQKKSNLLSEGIVLDVSSKTRLGEAIEKENPSLREVEIDNSSPMEKFKFEIKACGTKKGEGSLSVHDVTHLDKTPSKGLPQLNVTEKVTDASKDLSSRSSFAQSTLNTFVTMGKRKHENISTILSETPVLRNQTSSYRVEKSKFEVRALASRCLVEGDQLDDMVISKEDMTPSERDSELGNRISPGTQADNVERHEREHEKPIRFEEPTSDNTLTKGDVERVSEDNPRCSQPLRSVATVLDSPAQSTGPKMFSTLEFSFQNLRTRRLERLSRLQSTGYVSKCMNTPQPKKCFAAATLELSQPDDEERKARALAAATSELERLFRKEDFRRMQVLGQFNLGFIIAKLERDLFIVDQHAADEKFNFEHLARSTVLNQQPLLQPLNLELSPEEEVTVLMHMDIIRENGFLLEENPSAPPGKHFRLRAIPYSKNITFGVEDLKDLISTLGDNHGECSVASSYKTSKTDSICPSRVRAMLASRACRSSVMIGDPLRKNEMQKIVEHLADLESPWNCPHGRPTMRHLVDLTTLLTLPDDDNVNDDDDDDATISLA", "output": "Required for DNA mismatch repair (MMR), correcting base-base mismatches and insertion-deletion loops (IDLs) resulting from DNA replication, DNA damage or from recombination events between non-identical sequences during meiosis. Component of the MutLalpha heterodimer that forms a ternary complex with the MutS heterodimers, which initially recognize the DNA mismatches. This complex is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. Plays a major role in maintaining the genetic stability of simple sequence repeats and in the repair of heteroduplex sites present in meiotic recombination intermediates. Does not seem to be required for homologous somatic recombination."}]}
+{"id": "function_test_189", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MALALRRLSSSVKKPISLLSSNGGSLRFMSSLSTAAMAESEKSRSSWIKQLNASLDEIDPEVADIIELEKARQWKGFELIPSENFTSLSVMQAVGSVMTNKYSEGYPGARYYGGNEYIDMAETLCQKRALEAFQLDPSKWGVNVQSLSGSPANFQVYTALLKPHERIMALDLPHGGHLSHGYQTDTKKISAVSIFFETMPYRLDENTGYIDYDQLEKSAVLFRPKLIVAGASAYARLYDYARIRKVCNKQKAVMLADMAHISGLVAAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFFRKGLKEINKQGKEVMYDYEDRINQAVFPGLQGGPHNHTITGLAVALKQARTPEYKAYQDQVLRNCSKFAETLLAKGYDLVSGGTDNHLVLVNLKNKGIDGSRVEKVLELVHIAANKNTVPGDVSAMVPGGIRMGTPALTSRGFIEEDFAKVAEYFDLAVKIALKIKAESQGTKLKDFVATMQSNEKLQSEMSKLREMVEEYAKQFPTIGFEKETMRYKE", "output": "Functions outside the photorespiratory pathway in catalyzing the interconversion of serine and glycine with the conversion of tetrahydrofolate (THF) into 5,10-methylene-THF."}]}
+{"id": "function_test_190", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MVKLSNLLVATFGVLLVLNGCLARQSLGVPPQLQNECNLDNLDVLQATETIKSEAGQIEYWDHNHPQLRCVGVSVARYVIEQGGLYLPTFFTSPKISYVVQGTGISGRVVPGCAETFMDSQPMQGQQQGQPWQGRQGQQGQPWEGQGQQGQQGRQGQPWEGQGQQGQQGRQGQQGQPWEGQGQQGQQGFRDMHQKVEHVRRGDVFANTPGSAHWIYNSGEQPLVIIALLDIANYQNQLDRNPRVFHLAGNNQQGGFGGSQQQQEQKNLWSGFDAQVIAQALKIDVQLAQQLQNQQDSRGNIVRVKGPFQVVRPPLRQPYESEEWRHPRSPQGNGLEETICSMRSHENIDDPARADVYKPSLGRVTSVNSYTLPILEYVRLSATRGVLQGNAMVLPKYNMNANEILYCTGGQGRIQVVNDNGQNVLDQQVQKGQLVVIPQGFAYVVQSHGNKFEWISFKTNENAMISTLAGRTSLLRALPLEVISNGFQISPEEARKIKFNTLETTLTRAAGRQQQQLIEEIVEA", "output": "Seed storage protein."}]}
+{"id": "function_test_191", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTPSTPADDAWIRSYQRLLPESQSLLASRRSVIPVAISRVNQFDAARLDVEMSAMLKEQLVKVFTLMKPGMLFQYEPELDAFLEFLIWRFSIWVDKPTPGNALMNLRYRDERGVVAQHLGKVRTGLEGPGLTSPQKIWYCVASVGGQYLFSRLQSFSAFRRWGDSEQRPLARRLWTLVQRIEGIYKAASFLNLLSFLYTGRYRNLIEKALKARLVYRSPHMNRSVSFEYMNRQLVWNEFSEMLLLLLPLLNSSAVKNILSPFAKDKSSSTKEDTVTCPICQVDPAIPFIALPCQHRYCYYCIRTRCASAASFRCLRCNEPVVAIQREGVSSGK", "output": "E3 ubiquitin-protein ligase component of a retrotranslocation channel required for peroxisome organization by mediating export of the PEX5 receptor from peroxisomes to the cytosol, thereby promoting PEX5 recycling . The retrotranslocation channel is composed of PEX2, PEX10 and PEX12; each subunit contributing transmembrane segments that coassemble into an open channel that specifically allows the passage of PEX5 through the peroxisomal membrane (By similarity). PEX2 also regulates peroxisome organization by acting as a E3 ubiquitin-protein ligase . PEX2 ubiquitinates PEX5 during its passage through the retrotranslocation channel: catalyzes monoubiquitination of PEX5 at 'Cys-6', a modification that acts as a signal for PEX5 extraction into the cytosol (By similarity)."}]}
+{"id": "function_test_192", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKYLLDLILLLPLLIVFSIESLVKLFIPKKKKSVAGEIVLITGAGHGIGRLTAYEFAKLNTKLVLWDINKNGIEETAAKCRKLGAQAHPFVVDCSQREEIYSAAKKVKEEVGDVSILVNNAGVVYTADLFATQDPQIEKTFEVNVLAHFWTTKAFLPVMMKNNHGHIVTVASAAGHTVVPFLLAYCSSKFAAVGFHRALTDELAALGRTGVRTSCLCPNFINTGFIKNPSTNLGPTLEPEEVVEHLMHGILTEKQMIFVPSSIALLTVLERIVPERFLQVLKHRINVKFDAVVGYKDK", "output": "Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione."}]}
+{"id": "function_test_193", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MVVSQPITPGQVSFLLGVIPLMIAWLYSEFLEYRRSSFHAKVHSDKNLVELEMVTNKEDEGTVLMEGGLPRSASSKFYSSPIKTNLIRFLTLEDSFLLENRATLRAMAEFGAILLYFYICDRTSLIGQSQKNYSRDLFLFLFCLLIIVSAMTSLKKHTDKSPITGKSILYLNRHQTEEWKGWMQVLFLMYHYFAAVEFYNAIRVFIAGYVWMTGFGNFSYYYIRKDFSLARFTQMMWRLNFFVAFCCIILNNDYMLYYICPMHTLFTLMVYGALGIYSQYNEIASVMALKIASCFLVVILMWEIPGVFEIFWSPLAFLLGYTDPAKPDLPRLHEWHFRSGLDRYIWIIGMIYAYFHPTVERWMEKLEECDAKRRMSIKTSIIGISSFAGYLWYEYIYKLDKVTYNKYHPYTSWIPITVYICLRNCTQQLRRFSLTLFAWLGKITLETYISQFHIWLRSSVPNGQPKLLLSIIPEYPMLNFMLTTAIYVLVSVRLFELTNTLKSVFIPTKDDKRLLHNVIAMAAISFCLYIIGLILLLIPH", "output": "Probable O-acetyltransferase involved in the acetylation of xylan during secondary wall biosynthesis."}]}
+{"id": "function_test_194", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTFLFSTLQLSLFSLALVIFGYIFLRKQLSRCEVDSSTIPEPLGALPLFGHLHLLRGKKLLCKKLAAMSQKHGPIFSLKLGFYRLVVASDPKTVKDCFTTNDLATATRPNIAFGRYVGYNNASLTLAPYGDYWRELRKIVTVHLFSNHSIEMLGHIRSSEVNTLIKHLYKGNGGTSIVKIDMLFEFLTFNIILRKMVGKRIGFGEVNSDEWRYKEALKHCEYLAVIPMIGDVIPWLGWLDFAKNSQMKRLFKELDSVNTKWLHEHLKKRSRNEKDQERTIMDLLLDILPEDIVISGHVRDVIVKATILALTLTGSDSTSITLTWAVSLLLNNPAALEAAQEEIDNSVGKGRWIEESDIQNLKYLQAIVKETHRLYPPAPLTGIREAREDCFVGGYRVEKGTRLLVNIWKLHRDPKIWPDPKTFKPERFMEDKSQCEKSNFEYIPFGSGRRSCPGVNLGLRVVHFVLARLLQGFELHKVSDEPLDMAEGPGLALPKINPVEVVVMPRLDPKLYSLL", "output": "Involved in the biosynthesis of homoterpenes, attractants of herbivores parasitoids and predators (e.g. predatory mites and parasitoid wasps) . Catalyzes the conversion of the C20 (E,E)-geranyllinalool to C16-homoterpene 4,8,12-trimethyltrideca-1,3,7,11-tetraene (TMTT) of the C15 (E)-nerolidol to C11-homoterpene (E)-4,8-dimethyl-1,3,7-nonatriene (DMNT); these volatile compounds are produced upon insect herbivore attack and emitted from flowers and vegetative tissues during herbivore feeding . Required during resistance responses to the fungus Alternaria brassicae . Prevents oviposition of the phloem-feeding insect cabbage whitefly (Aleyrodes proletella) ."}]}
+{"id": "function_test_195", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTFSEILDRVGSMGPFQYLHVTLLALPVLGIANHNLLQIFTATTPVHHCRPPPNASIGPWVLPLDPNGKPEKCLRFVHLPNASLPNDTQRATEPCLDGWIYNSTRDTIVIEWDLVCSSNKLKEMAQSIFMAGILVGGPVIGELSDRFGRKPILTWSYLMLAASGSGAAFSPSLPVYMIFRFLCGCSISGISLSTVILNVEWVPTSMRAISSTSIGYCYTIGQFILSGLAYAIPQWRWLQLTSSAPFFIFSLLSWWVPESIRWLVLSGKYSKALKTLQRVATFNGKKEEGKKLTIEELKFNLQKDITSAKVKYGLSDLFRVSILRRVTFCLSLAWFSTGFAYYSLAMGVEEFGVNIYILQIIFGGVDIPAKFITILSLSYLGRRITQSFLLLLAGGAILALIFVPSEMQLLRTALAVFGKGCLSGSFSCLFLYTSELYPTVLRQTGMGISNVWARVGSMIAPLVKITGELQPFIPNVIFGTTALLGGSAAFFLLETLNRPLPETIEDIQNWHKQVQKTKQESEAEKASQIIPLKTGG", "output": "Functions as an organic anion/dicarboxylate exchanger that couples organic anion uptake indirectly to the sodium gradient . Transports organic anions such as estrone 3-sulfate (E1S) and urate in exchange for dicarboxylates such as glutarate or ketoglutarate (2-oxoglutarate) . Plays an important role in the excretion of endogenous and exogenous organic anions, especially from the kidney and the brain . Responsible for the transport of prostaglandin E2 (PGE2) and prostaglandin F2(alpha) (PGF2(alpha)) in the basolateral side of the renal tubule. May be involved in the basolateral transport of steviol, a metabolite of the popular sugar substitute stevioside (By similarity). May participate in the detoxification/ renal excretion of drugs and xenobiotics, such as the histamine H(2)-receptor antagonists fexofenadine and cimetidine, the antibiotic benzylpenicillin (PCG), the anionic herbicide 2,4-dichloro-phenoxyacetate (2,4-D), the diagnostic agent p-aminohippurate (PAH), the antiviral acyclovir (ACV), and the mycotoxin ochratoxin (OTA), by transporting these exogenous organic anions across the cell membrane in exchange for dicarboxylates such as 2-oxoglutarate (By similarity). Contributes to the renal uptake of potent uremic toxins (indoxyl sulfate (IS) and 3-carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF)), pravastatin, PCG, E1S and dehydroepiandrosterone sulfate (DHEAS), and is partly involved in the renal uptake of temocaprilat (an angiotensin-converting enzyme (ACE) inhibitor) . May contribute to the release of cortisol in the adrenals (By similarity). Involved in one of the detoxification systems on the choroid plexus (CP), removes substrates such as E1S or taurocholate (TC), PCG, 2,4-D and PAH, from the cerebrospinal fluid (CSF) to the blood for eventual excretion in urine and bile . Regulates the CSF concentration of histamine H(2)-receptor antagonists cimetidine and ranitidine at the CP . Also contributes to the uptake of several other organic compounds such as the prostanoids prostaglandin E(2) and prostaglandin F(2-alpha), L-carnitine, and the therapeutic drugs allopurinol, 6-mercaptopurine (6-MP) and 5-fluorouracil (5-FU) (By similarity). Mediates the uptake from brain of organic anions, such as E1S, PAH, and OTA . Mediates the transport of PAH, PCG, and the statins pravastatin and pitavastatin, from the cerebrum into the blood circulation across the blood-brain barrier (BBB) . In summary, plays a role in the efflux of drugs and xenobiotics, helping reduce their undesired toxicological effects on the body ."}]}
+{"id": "function_test_196", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MILLSSSISLSRPVSSQSFSPPAATSTRRSHSSVTVKCCCSSRRLLKNPELKCSLENLFEIQALRKCFVSGFAAILLLSQAGQGIALDLSSGYQNICQLGSAAAVGENKLTLPSDGDSESMMMMMMRGMTAKNFDPVRYSGRWFEVASLKRGFAGQGQEDCHCTQGVYTFDMKESAIRVDTFCVHGSPDGYITGIRGKVQCVGAEDLEKSETDLEKQEMIKEKCFLRFPTIPFIPKLPYDVIATDYDNYALVSGAKDKGFVQVYSRTPNPGPEFIAKYKNYLAQFGYDPEKIKDTPQDCEVTDAELAAMMSMPGMEQTLTNQFPDLGLRKSVQFDPFTSVFETLKKLVPLYFK", "output": "Lipocalin that prevents thylakoidal membrane lipids peroxidation and confers protection against oxidative stress, especially mediated by singlet oxygen in response to high light and other stress (e.g. heat shocks) . Required for seed longevity by insuring polyunsaturated lipids integrity ."}]}
+{"id": "function_test_197", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSNGRHLAKGSPMPDVPEDGILRLYSMRFCPFAQRVHLVLDAKQIPYHSIYINLTDKPEWLLEKNPQGKVPALEIVREPGPPVLTESLLICEYLDEQYPLRPLYPRDPLKKVQDKLLIERFRAVLGAFFKASDGGDLEPFWSGLDIYERELARRGTEFFGGEQTGILDYMIWPWCERLELLKLQRGEDYNYDQSRFPQLTLWLERMKRDPAVMAFYMEAEVQAEFLRTRSLGRPNYNLLVKDA", "output": "Mediates the conversion of 2-amino-4-oxo-6-pyruvoyl-5,6,7,8-tetrahydropteridine (6-PTP; also named 6-pyruvoyltetrahydropterin) to 2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido(4,5-b)[1,4]diazepin-4-one (pyrimidodiazepine or PDA), a key intermediate in red eye pigment drosopterin biosynthesis."}]}
+{"id": "function_test_198", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MQKSRDIKRTGVYRVSGNIGDLQLELKLRHISEWLPVPKFEYAGAQSTNAYGDHYPGSEEDIWQDCYIHVPQGDDSCGGKTGLGYNCSYYNVGIGYTGRRRRSPISQHEGEMEKDKNEGEITDLESQSNRSWSILSDNSRPPAGDLFYKRNKELCNGAIATIRISWQQKHFSQAELEQYINNPGSCASKLQRRYHRWALETLKLQQRYLRKLENLEDAETVEDPEPITIRRRIRKPKAKQRGCSAAAHPTITSLSSANMSEVSILDDPNFAARTCLIHTLLDNDSESLMPAEASEFHKKGYQLMYIYADLQQDTLLVSIRYDPEQGLLYVYPDFSSSAQDLDYVIQIERNNDCRQLYAFGFENVTPLEAYDDDGFSEEADGEDEQELGDGLPIEEDLPEEASAEEILEFYRRRREAASERRSLLQFEMPPKRMKRVSLLLELQEGQNFENPNIHVRYYLKAPANTFYEGTPGVDTMQGATATCRNAGDWRSAHLGHCWQVTLLLEEQHHPADLLHLYFEVISIDSWQRERCEGYAHYAIPLTSALPTDSIRLQCIRPLGNWLDALNRYFIGGRQLFDFESFFDVHRQSEMHSRLNFNSDRPMTTTGTLSLRLQKLQQRQIDTSDQFHHHFHLELGNDSSDDGDSNDDDVRSSSNPDTSRATTLDEVMAAFVEARKRIELLLGNSSETASPSSAYYQAEF", "output": "Probable component of the tectonic-like complex (also named MKS complex), a complex localized at the transition zone of primary cilia . Required for ciliary structure and function ."}]}
+{"id": "function_test_199", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDSDEGYNYEFDEDEECSEEDSGAEEEEDDDEDEPDDDNLDLGEVELVEPGLGVGGERDGLLCGETGGGGGSALGPGGGGGGGGGGGGPGHEQEEDYRYEVLTAEQILQHMVECIREVNEVIQNPATITRILLSHFNWDKEKLMERYFDGNLEKLFAECHVINPSKKSRTRQMNTRSSAQDMPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTISCPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYPDAKPVRCKCGRQFCFNCGENWHDPVKCKWLKKWIKKCDDDSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNCNRYNEDDAKAARDAQERSRAALQRYLFYCNRYMNHMQSLRFEHKLYAQVKQKMEEMQQHNMSWIEVQFLKKAVDVLCQCRATLMYTYVFAFYLKKNNQSIIFENNQADLENATEVLSGYLERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHEGYEKDLWEYIED", "output": "E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 UBE2L3. Acts as an atypical E3 ubiquitin-protein ligase by working together with cullin-RING ubiquitin ligase (CRL) complexes and initiating ubiquitination of CRL substrates: associates with CRL complexes and specifically mediates addition of the first ubiquitin on CRLs targets. The initial ubiquitin is then elongated by CDC34/UBE2R1 and UBE2R2. E3 ubiquitin-protein ligase activity is activated upon binding to neddylated cullin-RING ubiquitin ligase complexes. Plays a role in protein translation in response to DNA damage by mediating ubiquitination of EIF4E2, the consequences of EIF4E2 ubiquitination are however unclear. According to a report, EIF4E2 ubiquitination leads to promote EIF4E2 cap-binding and protein translation arrest. According to another report EIF4E2 ubiquitination leads to its subsequent degradation. Acts as the ligase involved in ISGylation of EIF4E2. In vitro, controls the degradation of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex member SUN2 and may therefore have a role in the formation and localization of the LINC complex, and as a consequence, may act in nuclear subcellular localization and nuclear morphology."}]}
+{"id": "function_test_200", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAVNDCFSLTYPHNPHPGDLIEVFRPCYQHWALYLGDGYVINIAPVDGIPSSFSSAKSVFSTKALVKMQLLKDVVGNDTYRINNKYDTTYPPLPVEEVIQRSEFAIGQEVTYDLLVNNCEHFVTLLRYGEGVSEQANRAIGTIGLVAAGIDIFTFLGLFPKRQGAKS", "output": "Exhibits both phospholipase A1/2 and acyltransferase activities (By similarity). Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids (By similarity). Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid (By similarity)."}]}
+{"id": "function_test_201", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEEDQEEPPSSSTSSESPEVVLKAPKAPTRRRKNSKKDRRQDMEVDDGEKESTAQYCKGFYDALRVMQTTNKYEFTGGAVSSPVLPVLQTAAFSPITPASASDMHTIVMSLLGNTPITSGPSIAPLSSPTLLPLVTSGDLDDLSMKILASSAIPGPPIISSSNSPDSSTTAVTTSQITAFQPLLNNFVSSTTASTSRPDKLNLTPPQQSAEIYAFNGVNSDDSDGGLDSRSASRCGMALDDQEKKKLERKRARNRQAATKCRQKKMDRIKELEEQVLHEKHRGQRLDAELLELNRALEHFRRTVEHHSGNGCPNNSIRV", "output": "Transcription factor that recognizes and binds to the AP-1 non-canonical enhancer heptamer motif 5'-TTAGTCA-3' . Required for ovulation . Controls plc-1 expression in the spermatheca to regulate spermathecal valve dilation ."}]}
+{"id": "function_test_202", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAFANLRKILISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAEKLQVVGRAGTGVDNVDLEAATRKGVLVMNTPNGNSLSAAELTCGMLMCLARQIPQATASMKDGKWDRKKFMGTELNGKTLGILGLGRIGREVAARMQAFGMKTVGYDPIISPEVAASFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFTEEPPRDRALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDMVKGKSLTGVVNAQALTSAFSPHTKPWIGLAEALGTLMHAWAGSPKGTIQVVTQGTSLKNAGTCLSPAVIVGLLREASKQADVNLVNAKLLVKEAGLNVTTSHSPGVPGEQGIGECLLTVALAGAPYQAVGLVQGTTPMLQMLNGAVFRPEVPLRRGQPLLLFRAQPSDPVMLPTMIGLLAEAGVQLLSYQTSKVSDGDTWHVMGLSSLLPSLDAWKQHVSEAFQFCF", "output": "Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Does not catalyze the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate."}]}
+{"id": "function_test_203", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEVAPEQPRWMAHPAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDVFFNHLDSQGNPYYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHSPWTVSPFSKTPLHPSAAGAPGGPLSVYPGAAGGSGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKEVSPDPSTTGAASPASSSAGGSVARGEDKDGVKYQVSLSESMKMEGGSPLRPGLATMGTQPATHHPIPTYPSYVPAAAHDYGSSLFHPGGFLGGPASSFTPKQRSKARSCSEGRECVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSSKSKKSKKGAECFEELSKCMQEKSPPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSSMVTAMG", "output": "Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'-AGATAG-3'."}]}
+{"id": "function_test_204", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSETLQLRGTLIGHNGWVTQIATNPKDPDTIISASRDKTLIVWKLTRDEDTNYGYPQKRLYGHSHFISDVVLSSDGNYALSGSWDQTLRLWDLAAGKTTRRFEGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLAECKFTIQEDGHTDWVSCVRFSPNHSNPIIVSCGWDRTVKVWNLANCKLKNNHHGHNGYLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNLYTLEHNDIINALCFSPNRYWLCVAYGPSIKIWDLACKKTVEELRPEVVSPTSKADQPQCLSLAWSTDGQTLFAGYSDNTIRVWQVSVSAH", "output": "Involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes (By similarity)."}]}
+{"id": "function_test_205", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSEGAAGASPPGAASAAAASAEEGTAAAAAAAAAGGGPDGGGEGAAEPPRELRCSDCIVWNRQQTWLCVVPLFIGFIGLGLSLMLLKWIVVGSVKEYVPTDLVDSKGMGQDPFFLSKPSSFPKAMETTTTTTSTTSPATPSAGGAASSRTPNRISTRLTTITRAPTRFPGHRVPIRASPRSTTARNTAAPPTVLSTTAPFFSSSTPGSRPPMPGAPSTQAMPSWPTAAYATSSYLHDSTPSWTLSPFQDAAAASSSSPSSTSSTTTTPETSTSPKFHTTTYSTERSEHFKPCRDKDLAYCLNDGECFVIETLTGSHKHCRCKEGYQGVRCDQFLPKTDSILSDPTDHLGIEFMESEDVYQRQVLSISCIIFGIVIVGMFCAAFYFKSKKQAKQIQEHLKESQNGKNYSLKASSTKSESLMKSHVHLQNYSKADRHPVTALEKIMESSFSAPQSFPEVTSPDRGSQPIKHHSPGQRSGMLHRNTFRRAPPSPRSRLGGIVGPAYQQLEESRIPDQDTIPCQGIEVRKTISHLPIQLWCVERPLDLKYVSNGLRTQQNASINMQLPSRETNPYFNSLDQKDLVGYLSPRANSVPIIPSMGLEETCMQMPGISDVKSIKWCKNSYSADIVNASMPVSDCLLEEQQEVKILLETVQEQIRILTDARRSEDFELASMETEDSASENTAFLPLSPTAKSEREAQFVLRNEIQRDSVLTK", "output": "Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors."}]}
+{"id": "function_test_206", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MMNKSNFEFLKGVNDFTYAIACAAENNYPDDPNTTLIKMRMFGEATAKHLGLLLNIPPCENQHDLLRELGKIAFVDDNILSVFHKLRRIGNQAVHEYHNDLNDAQMCLRLGFRLAVWYYRLVTKDYDFPVPVFVLPERGENLYHQEVLTLKQQLEQQVREKAQTQAEVEAQQQKLVALNGYIAILEGKQQETEAQTQARLAALEAQLAEKNAELAKQTEQERKAYHKEITDQAIKRTLNLSEEESRFLIDAQLRKAGWQADSKTLRFSKGARPEPGVNKAIAEWPTGKDETGNQGFADYVLFVGLKPIAVVEAKRNNIDVPARLNESYRYSKCFDNGFLRETLLEHYSPDEVHEAVPEYETSWQDTSGKQRFKIPFCYSTNGREYRATMKTKSGIWYRDVRDTRNMSKALPEWHRPEELLEMLGSEPQKQNQWFADNPGMSELGLRYYQEDAVRAVEKAIVKGQQEILLAMATGTGKTRTAIAMMFRLIQSQRFKRILFLVDRRSLGEQALGAFEDTRINGDTFNSIFDIKGLTDKFPEDSTKIHVATVQSLVKRTLQSDEPMPVARYDCIVVDEAHRGYILDKEQTEGELQFRSQLDYVSAYRRILDHFDAVKIALTATPALHTVQIFGEPVYRYTYRTAVIDGFLIDQDPPIQIITRNAQEGVYLSKGEQVERISPQGEVINDTLEDDQDFEVADFNRGLVIPAFNRAVCNELTNYLDPTGSQKTLVFCVTNAHADMVVEELRAAFKKKYPQLEHDAIIKITGDADKDARKVQTMITRFNKERLPNIVVTVDLLTTGVDIPSICNIVFLRKVRSRILYEQMKGRATRLCPEVNKTSFKIFDCVDIYSTLESVDTMRPVVVRPKVELQTLVNEITDSETYKITEADGRSFAEHSHEQLVAKLQRIIGLATFNRDRSETIDKQVRRLDELCQDAAGVNFNGFASRLREKGPHWSAEVFNKLPGFIARLEKLKTDINNLNDAPIFLDIDDEVVSVKSLYGDYDTPQDFLEAFDSLVQRSPNAQPALQAVINRPRDLTRKGLVELQEWFDRQHFEESSLRKAWKETRNEDIAARLIGHIRRAAVGDALKPFEERVDHALTRIKGENDWSSEQLSWLDRLAQALKEKVVLDDDVFKTGNFHRRGGKAMLQRTFDDNLDTLLGKFSDYIWDELA", "output": "The subtype A restriction (R) subunit of a type I restriction enzyme that recognizes 5'-AACN(6)GTGC-3' and cleaves a random distance away. The R subunit is required for both endonuclease and ATPase activities but not for modification . Has endonucleolytic activity that requires Mg(2+), ATP and S-adenosyl-L-methionine (SAM); ATP can be replaced by dATP, no tested molecule could substitute for SAM. Generates double-stranded DNA with no nicks, by cutting one strand then the other within a few seconds. Cleaves only non-methylated DNA, hemi-methylated and fully methylated DNA are not substrates . After locating a non-methylated recognition site, the enzyme complex serves as a molecular motor that translocates DNA in an ATP-dependent manner until a collision occurs that triggers cleavage ."}]}
+{"id": "function_test_207", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MCGIFGYCNYLVERSRGEIIDTLVDGLQRLEYRGYDSTGIAIDGDEADSTFIYKQIGKVSALKEEITKQNPNRDVTFVSHCGIAHTRWATHGRPEQVNCHPQRSDPEDQFVVVHNGIITNFRELKTLLINKGYKFESDTDTECIAKLYLHLYNTNLQNGHDLDFHELTKLVLLELEGSYGLLCKSCHYPNEVIATRKGSPLLIGVKSEKKLKVDFVDVEFPEENAGQPEIPLKSNNKSFGLGPKKAREFEAGSQNANLLPIAANEFNLRHSQSRAFLSEDGSPTPVEFFVSSDAASVVKHTKKVLFLEDDDLAHIYDGELHIHRSRREVGASMTRSIQTLEMELAQIMKGPYDHFMQKEIYEQPESTFNTMRGRIDYENNKVILGGLKAWLPVVRRARRLIMIACGTSYHSCLATRAIFEELSDIPVSVELASDFLDRKCPVFRDDVCVFVSQSGETADTMLALNYCLERGALTVGIVNSVGSSISRVTHCGVHINAGPEIGVASTKAYTSQYIALVMFALSLSDDRVSKIDRRIEIIQGLKLIPGQIKQVLKLEPRIKKLCATELKDQKSLLLLGRGYQFAAALEGALKIKEISYMHSEGVLAGELKHGVLALVDENLPIIAFGTRDSLFPKVVSSIEQVTARKGHPIIICNENDEVWAQKSKSIDLQTLEVPQTVDCLQGLINIIPLQLMSYWLAVNKGIDVDFPRNLAKSVTVE", "output": "Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins)."}]}
+{"id": "function_test_208", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDGLPGRALGAACLLLLAAGWLGPEAWGSPTPPPSPAAPPPPPPPGAPGGSQDTCTSCGGGGGGFRRPEELGRVDGDFLEAVKRHILSRLQLRGRPNITHAVPKAAMVTALRKLHAGKVREDGRVEIPHLDGHASPGADGQERVSEIISFAETDGLASSRVRLYFFVSNEGNQNLFVVQASLWLYLKLLPYVLEKGSRRKVRVKVYFQEQGHGDRWNVVEKKVDLKRSGWHTFPITEAIQALFERGERRLNLDVQCDSCQELAVVPVFVDPGEESHRPFVVVQARLGDSRHRIRKRGLECDGRTSLCCRQQFFIDFRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPGPVNSCCIPTKLSSMSMLYFDDEYNIVKRDVPNMIVEECGCA", "output": "Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins."}]}
+{"id": "function_test_209", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MMPRLLFRAWPRCPSLVLGAPSRPLSAVSGPDDYLQHSIVPTMHYQDSLPRLPIPKLEDTMKRYLNAQKPLLDDSQFRRTEALCKNFETGVGKELHAHLLAQDKQNKHTSYISGPWFDMYLTARDSIVLNFNPFMAFNPDPKSEYNDQLTRATNLTVSAVRFLKTLQAGLLEPEVFHLNPSKSDTDAFKRLIRFVPPSLSWYGAYLVNAYPLDMSQYFRLFNSTRIPRPNRDELFTDTKARHLLVLRKGHFYVFDVLDQDGNIVNPLEIQAHLKYILSDSSPVPEFPVAYLTSENRDVWAELRQKLIFDGNEETLKKVDSAVFCLCLDDFPMKDLIHLSHTMLHGDGTNRWFDKSFNLIVAEDGTAAVHFEHSWGDGVAVLRFFNEVFRDSTQTPAITPQSQPAATNSSASVETLSFNLSGALKAGITAAKEKFDTTVKTLSIDSIQFQRGGKEFLKKKQLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASIFTKRCSEAFVRDPSKHSVGELQHMMAECSKYHGQLTKEAAMGQGFDRHLYALRYLATARGLNLPELYLDPAYQQMNHNILSTSTLNSPAVSLGGFAPVVPDGFGIAYAVHDDWIGCNVSSYSGRNAREFLHCVQKCLEDIFDALEGKAIKT", "output": "Involved in the intramitochondrial synthesis of acylcarnitines from accumulated acyl-CoA metabolites. Reconverts acylcarnitines back into the respective acyl-CoA esters that can then undergo beta-oxidation, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Active with medium (C8-C12) and long-chain (C14-C18) acyl-CoA esters."}]}
+{"id": "function_test_210", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MFPRASALAKCMATVHRRGLLTSGAQSLVSKPVSEGDPEMFDILQQERHRQKHSITLIPSENFTSKAVMDLLGSELQNKYSEGYPGERYYGGNEIIDKSESLCQARALELYGLDPAKWGVNVQPLSGAPANLYVYSAIMNVGERLMGLDLPDGGHLSHGYQLKSGTPISFISKYFQSMPYHVDHTTGLIDYDNLQVLAKAFRPKVIVAGTSAYSRLIDYARFKEISQGCGAYLMSDMAHISGLVAANVVPSPFEHSDIVTTTTHKSLRGPRGAMIFFRKGIKSVTKKGKEIPYELEKKINFSVFPGHQGGPHNHTIGAMAVALKQAMSPEFKEYQQKIVDNSKWFAQELTKMGYKLVSGGTDNHLIVIDLSGTQVDGARVETILSALNIAANKNTIPGDKSALFPSGLRIGTPAMTTRGFGREEFSQVAKYIDSAVKLAENLKTLEPTTKLDARSRLNEFKKLCNESSEVAALSGEISKWVGQYPVPGDI", "output": "Interconversion of serine and glycine."}]}
+{"id": "function_test_211", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLKSASQNFFRAYSSRIGRYAATASGKLAQSRLSNIPTPKALKKFLDEYIVGQEIGKKVLSVAVYNHYLRINDKQKKGELQRQRELMEREKIADDRDEPIFSGNSESKAGWRNLQRQFNLAGREVDEDLELSKSNVLVVGPSGSGKTLLATTLAKILNVPIAITDCTQLTQAGYIGEDVEVCIERLLVNAEFDVARAEKGIIVLDEIDKLAKPAASIGTKDVSGEGVQQSLLKIIEGHKVEITVKRPVKHDIDGQKNQTTTKKDEVFVVDTSNILFMIMGAFVGLDKHIVKRIEDMKKIQKAGESVESSNSKEVEKERAKKFRFSNTLEQVELDNGKKVCALDLTTPTDLVSFGLIPELIGRVPIITALQPLQRDDLFHILKEPKNALLDQYEYIFKQFGVRLCVTQKALKKVAQFALKEGTGARGLRGIMERLLLNVNYDCPGSNIAYVLIDEATVDSLQETEHSLASQVDVKYYSGDEKDSLIRDVSEEDKKLGVMLEKELGHSANIHTPTIPKRSLT", "output": "ATP-dependent unfoldase that stimulates the incorporation of the pyridoxal phosphate cofactor into 5-aminolevulinate synthase (HEM1), thereby activating 5-aminolevulinate (ALA) synthesis, the first step in heme biosynthesis. Up-regulates heme biosynthesis."}]}
+{"id": "function_test_212", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDTAGKVIKCKAAVLWGTNQPFSIEDIEVAPPKAKEVRVKILATGICGTDDHVIKGTMVSKFPVIVGHEAVGIVESVGEEVTTVRPGDKVIPLFLPQCRECNPCRNPEGNLCIRSDLTGRGVLADGTTRFTCKGKPVQHFMNTSTFTEYTVLDESSVAKIDAEAPPEKACLIGCGFSTGYGAAVKTAKVSPGSTCAVFGLGGVGLSVVMGCKAAGASRIIGIDINKDKFQKALDVGATECINPRDFTKPISEVLSDMTGNTVQYTFEVIGRLETMVDALSSCHMNYGTSVVVGAPPSAKMLSYDPMLLFTGRTWKGCVFGGWKSRDDVPKLVTEFLEKKFDLGQLITHTLPFHNISEGFELLYSGQSIRTVLTF", "output": "Catalyzes the NAD-dependent oxidation of all-trans-retinol, alcohol, aldehyde and omega-hydroxy fatty acids and their derivatives. Oxidizes preferentially all trans-retinol, all-trans-4-hydroxyretinol, 9-cis-retinol, 2-hexenol, and long chain omega-hydroxy fatty acids such as juniperic acid. In vitro can also catalyzes the NADH-dependent reduction of all-trans-retinal and aldehydes and their derivatives. Reduces preferentially all trans-retinal, all-trans-4-oxoretinal and hexanal. Catalyzes in the oxidative direction with higher efficiency. Therefore may participate in retinoid metabolism, fatty acid omega-oxidation, and elimination of cytotoxic aldehydes produced by lipid peroxidation."}]}
+{"id": "function_test_213", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MVTGEENVYLKSSLSILKELSLDELLNVQYDVTTLIAKRVQALQNRNKCVLEEPNSKLAEILCHEKNAPQQSSQTSAGPGEQDSEDFILTQFDEDIKKESAEVHYRNENKHTVQLPLVTMPPNRHKRKISEFSSPLNGLNNLSDLEDCSDTVIHEKDNDKENKTRKLLGIELENPESTSPNLYKNVKDNFLFDFNTNPLTKRAWILEDFRPNEDIAPVKRGRRKLERFYAQVGKPEDSKHRSLSVVIESQNSDYEFAFDNLRNRSKSPPGFGRLDFPSTQEGNEDKKKSQEIIRRKTKYRFLMASNNKIPPYEREYVFKREQLNQIVDDGCFFWSDKLLQIYARC", "output": "Endonuclease that cooperates with the MRX complex in processing meiotic and mitotic double-strand breaks by allowing the endonucleolytic removal of SPO11 from the break sites and ensuring both resection and intrachromosomal association of the broken ends. Required for proper recovery from checkpoint-mediated cell cycle arrest after DNA damage. MRX complex and SAE2 remove a small oligonucleotide(s) from the DNA ends to form an early intermediate which is rapidly processed by EXO1 and/or SGS1 to generate extensive tracts of single-stranded DNA that serve as substrate for RAD51. Plays a transitional role in the dissociation of MRE11 from, and the recruitment of RAD52 to, repair foci. Ensures that both ends of a DSB participate in a recombination event and impairs the formation of palindromic structures in the genome. With TEL1, promotes microhomology-mediated end joining (MMEJ) but inhibits non-homologous end joining (NHEJ), likely by regulating MRE11-dependent ssDNA accumulation at DNA break. SAE2 and MRX are particularly important for removal of hairpins, bulky adducts and other irregular end structures. Facilitates telomere length reequilibration and subsequent checkpoint switch off. Involved in homing efficiency of VMA1 intein VDE and in repair of transposon excision sites."}]}
+{"id": "function_test_214", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGELRFKHLFWGSFVESGGTFQTVLIFLLIPCSLTVDYRAAPILSNTTFLWIWNVPTERCVGNVNDPIDLSFFSLIGSPRKTATGQPVTLFYVDRLGLYPHIDANQAEHYGGIPQRGDYQAHLRKAKTDIEHYIPDDKLGLAIIDWEEWRPTWLRNWKPKDNYRNKSIELVQSTNPGLSITEATQKAIQQFEEAGRKFMEGTLHLGKFLRPNQLWGYYLFPDCYNNKFQDPKYDGQCPAVEKKRNDNLKWLWKASTGLYPSVYLKKDLKSNRQATLYVRYRVVEAIRVSKVGNASDPVPIFVYIRLVFTDRTSEYLLEDDLVNTIGEIVALGTSGIIIWDAMSLAQRAAGCPILHKYMQTTLNPYIVNVTLAAKMCSQTLCNEKGMCSRRKESSDVYLHLNPSHFDIMLTETGKYEVLGNPRVGDLEYFSEHFKCSCFSRMTCKETSDVKNVQDVNVCVGDNVCIKAKVEPNPAFYLLPGKSLLFMTTLGHVLYHLPQDIFVFPRKTLVSTP", "output": "Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid."}]}
+{"id": "function_test_215", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSAWLLPAGGLPGAGFCVPARQSPSSFSRVLRWPRPGLPGLLLLLLLPSPSALSAVFKVGVLGPWACDPIFARARPDLAARLAANRLNRDFALDGGPRFEVALLPEPCLTPGSLGAVSSALSRVSGLVGPVNPAACRPAELLAQEAGVALVPWGCPGTRAAGTTAPAVTPAADALYVLLRAFRWARVALITAPQDLWVEAGRALSTALRARGLPVALVTSMETSDRSGAREALGRIRDGPRVRVVIMVMHSVLLGGEEQRYLLEAAEELALTDGSLVFLPFDTLHYALSPGPEALAAFVNSSQLRRAHDAVLTLTRRCPPGGSVQDSLRRAQEHQELPLDLNLKQVSPLFGTIYDAVFLLAGGVKRARTAVGGGWVSGASVARQVREAQVSGFCGVLGRTEEPSFVLLDTDASGEQLFATHLLDPVLGSLRSAGTPMHFPRGGPAPGPDPSCWFDPDVICNGGVEPGLVFVGFLLVIGMGLTGAFLAHYLRHRLLHMQMASGPNKIILTLEDVTFLHPPGGSSRKVVQGSRSSLATRSASDIRSVPSQPQESTNVGLYEGDWVWLKKFPGEHHMAIRPATKTAFSKLRELRHENVALYLGLFLAGTADSPATPGEGILAVVSEHCARGSLHDLLAQREIKLDWMFKSSLLLDLIKGMRYLHHRGVAHGRLKSRNCVVDGRFVLKVTDHGHGRLLEAQRVLPEPPSAEDQLWTAPELLRDPSLERRGTLAGDVFSLAIIMQEVVCRSTPYAMLELTPEEVIQRVRSPPPLCRPLVSMDQAPMECIQLMTQCWAEHPELRPSMDLTFDLFKSINKGRKTNIIDSMLRMLEQYSSNLEDLIRERTEELEQEKQKTDRLLTQMLPPSVAEALKMGTSVEPEYFEEVTLYFSDIVGFTTISAMSEPIEVVDLLNDLYTLFDAIIGAHDVYKVETIGDAYMVASGLPQRNGQRHAAEIANMSLDILSAVGSFRMRHMPEVPVRIRIGLHSGPCVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIHVNMSTVRILRALDQGFQMECRGRTELKGKGIEDTYWLVGRLGFNKPIPKPPDLQPGASNHGISLQEIPPERRKKLEKARPGQFTGK", "output": "Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment . May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane ."}]}
+{"id": "function_test_216", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDLLKLNRSLQGPGPGSGSSLCRPGVSLLNSSSAGNLSCETPRIRGTGTRELELTIRITLYAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLNLAAIALERYSAICRPLQARVWQTRSHAARVILATWLLSGLLMVPYPVYTVVQPVGPRILQCMHLWPSERVQQMWSVLLLILLFFIPGVVMAVAYGLISRELYLGLRFDGDNDSETQSRVRNQGGLPGGAAAPGPVHQNGGCRHVTSLTGEDSDGCYVQLPRSRLEMTTLTTPTTGPGPGPRPNQAKLLAKKRVVRMLLVIVLLFFVCWLPVYSANTWRAFDGPGARRALAGAPISFIHLLSYTSACANPLVYCFMHRRFRQACLDTCARCCPRPPRARPRPLPDEDPPTPSIASLSRLSYTTISTLGPG", "output": "Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity)."}]}
+{"id": "function_test_217", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MFGLPQQEVSEEEKRAHQEQTEKTLKQAAYVAAFLWVSPMIWHLVKKQWK", "output": "Component of the TOM (translocase of outer membrane) receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. TOM5 is involved in insertion of preproteins into the TOM40 translocation pore."}]}
+{"id": "function_test_218", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRTLSLLTLLALAALCLSDLTDAKPSGPESDKAFMSKQEGNKVVNRLRRYLGASVPSPDPLEPTREQCELNPACDELSDQYGLKTAYKRIYGITI", "output": "Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium."}]}
+{"id": "function_test_219", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGWSTAWCSVLALWLLWCAVCSNAASGDGNAFPFDIEGSAVVGRQDPSETSDSGVTLGRLPPAAERCDAGFFRTLSGECAPCDCNGNSHECLDGSGFCLHCQRNTTGEHCEKCLDGYIGDSIRGTPRFCQPCPCPLPHLANFAESCYRKNGAVRCICKENYVGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEITGQCRNCLRNTTGFKCERCAPGYYGDARTAKNCAVCNCGGGPCDSVTGECLEEGFEVPTGCDKCVWDLTDDLRLAALSIEESKSGLLSVSSGAAAHRHVTDMNSTIHLLRTRLSERENQYTLRKIQINNSENTLRSLLPDVEGLHEKGSQASRKGMLVEKESMDTIDQATHLVEQAHNMRDKIQEINSKMLYYGENQELGPEEIAEKLVLAQKMLEEIRSRQPFLTHRELVDEEADEAQELLSQAENWQRLHNDTRSLFPVVLEQLDDYNAKLSDLQESINQALDHVRDAEDMNRAITFKQRDHEKQHERVKEQMEVVGASLSMSADSLTIPQLTLEELDEIIKNASGIYAEIDGAKNELQGKLSNLSNLSHDLVQEATDHAYNLQQEADELSRNLHSSDMNGLVQKALDASNVYENIANYVSEANETAELALNITDRIYDAVSGIDTQIIYHKDESDNLLNQARELQAKADSSNDEAVADTSRRVGGALWRKGALRDRLNDAVKQLQAAERGDAHQRLGQSKLFIEEANKTTAAVQQVTTPMANNLSNWSQNLQTFDSSAYNTAVDSARDAVRNLTEVVPQLLDQLRTVEQKRPASNISASIQRIRELIAQTRSVASKIQVSMMFDGQSAVEVHPKVSVDDLKAFTSISLYMKPPPKPAEPTGAWVADQFVLYLGSKNAKKEYMGLAIKNDNLVYVYNLGMKDVEILLDSKPVSSWPAYFSIVKIERVGKHGKVFLTVPSLSSTAEEKFIKKGEFAGDDSLLDLTPEDTVFYVGGVPANFKLPASLNLPSYSGCLELATLNNDVISLYNFKHIYNMDPSKSVPCARDKLAFTQSRAASYFFDGSSYAVVRDITRRGKFGQVTRFDIEIRTPADNGLVLLMVNGSMFFSLEMRNGYLHVFYDFGFSNGPVHLEDTLKKAQINDAKYHEISIIYHNDKKMILVVDRRHVKSTDNEKKKIPFTDIYIGGAPQEVLQSRTLRAHLPLDINFRGCMKGFQFQKKDFNLLEQTETLGVGYGCPEDSLISRRAYFNGQSFIASIQKISFFDGFEGGFNFRTLQPNGLLFYYTSGSDVFSISLDNGTVVMDVKGIKVMSTDKQYHDGLPHFVVTSISDTRYELVVDKSRLRGKNPTKGKAEQTQTTEKKFYFGGSPISPQYANFTGCISNAYFTRLDRDVEVEDFQRYSEKVHTSLYECPIESSPLFLLHKKGKNSSKPKTNKQGEKSKDAPSWDPIGLKFLEQKAPRDSHCHLSSSPRAIEHAYQYGGTANSRQEFEHEQGDFGEKSQFAIRLKTRSSHGMIFYVSDQEENDFMTLFLAHGRLVFMFNVGHKKLKIRSQEKYNDGLWHDVIFIREKSSGRLVIDGLRVLEERLPPSGAAWKIKGPIYLGGVAPGRAVKNVQITSVYSFSGCLGNLQLNGASITSASQTFSVTPCFEGPMETGTYFSTEGGYVVLDESFNIGLKFEIAFEVRPRSSSGTLVHGHSVNGEYLNVHMRNGQVIVKVNNGVRDFSTSVTPKQNLCDGRWHRITVIRDSNVVQLDVDSEVNHVVGPLNPKPVDHREPVFVGGVPESLLTPRLAPSKPFTGCIRHFVIDSRPVSFSKAALVSGAVSINSCPTA", "output": "Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components."}]}
+{"id": "function_test_220", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPVEKDLKTAYKALYDEKEPLKALHLYDEILKGSPTNLTALIFKAACLEKLYFGFSDWHSDATMENAKELLDKALMTAEGRGDRSKIGLVNFRYFVHFFNIKDYELAQSYFKKAKNLGYVDDTLPLWEDRLETKLNKKNKKQKDSTNKHTIKPVESIENRGDNNSSHSPISPLKIETAPQESPKFKIDWYQSSTSVTISLFTVNLPESKEQVNIYISPNDRRTLSISYQVPKSGSEFQYNAKLSHEVDPKAVSLKIFPKKLEITLSKIDSTQWKKLEEDILTESSRLSDEGKNSDSATRLLSAETASKERLSYPSSSKKKIDWSKLDIDEEADEEAGSADSFFQKLYAGADPDTKRAMMKSFIESNGTALSTDWEDVSKGTVKTSPPEGMEPKHW", "output": "Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Required for both entry into S phase and kinetochore function. Also involved in cyclic AMP (cAMP) pathway, possibly by participating in the assembly or the conformational activation of specific multiprotein complexes."}]}
+{"id": "function_test_221", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MADQTASAEVATEKMDTAEAPAAAPAASAAAPAEAESNENTTVPSNVLSANGGQQTGNQSAPRNTSTVPTRQYLDSTVVPILLQGLGALAKDRPENPIEFLANFLLREKDRYNAENQNPAGQQ", "output": "Essential for dosage compensation . Required for the sex-specific association of the dosage compensation complex proteins dpy-27 and dpy-26 with the hermaphrodite X chromosomes . Plays a role in developmental rate and body fat regulation downstream of the TOR complex 2 . Required for the robust transdifferentiation of the Y rectal cell to the PDA motor neuron during larval development ."}]}
+{"id": "function_test_222", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLLTRRFSSALARSPLLPRSLPPPRAVPATPPAPRPPPRRLMSSSSSGWHHSSRPPPPPPSGADKDQLFRGLEAALGTTFSSEPLAPPPQPMILVISGPSGVGKDAVIQRLQEEREGMHFVVTATSRAKRPGEVDGKDYYFVTKEEFLTMIERKELLEYALVYGEYKGIPKQQIRDYMAKGYDIVLRVDIQGAATLREILGESAIFIFLVAESEEALVKRLIHRKTETSDMLLVRVATAREEVKRMNNFDYVVVNSEGNLEGAVKQVESIIDAEKAKVHKRTVNI", "output": "Essential for recycling GMP and indirectly, cGMP. Essential for chloroplast differentiation at early stage of leaf development. May not be involved in the synthesis and maintenance of the organellar DNA during leaf development."}]}
+{"id": "function_test_223", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKRHVSLSDILTGNKRKVRRQDALQITIDDENDTESGTFDARTAKHDDSSVIFLNHSVVKPIEAVSTNHKSAKEFLMTKRTKEKCDDDDDDLIVISDKSPKSETNCSKIALSQEHEDDISIISTSRIKSSLLNERASKIKNFLKHETTDTFKRLNSISKLNEIEPPLPLHQSIFPVGDKELSDRSVDIPLPFRTIPPLNHNFLPSDYESLKDKNSASCIPVRYQAPVLLGTNIKRNTTLTWPQLFKPVTLKQVLIEPKLKLRIKNWIETSFHTLEKPTLRNRLLNRINPNKQQGSGDELANFIVPDLEEDENLRPDFYRNGEANSSLSEFVPLMILHGNSIGKKTLIQTIMREIAGDDNSYQIYEVNSNMNRSKKDLLDILLDFTTTHYVKDSSKRKSDYGLVLFNDVDVLFKEHDRGYWAMISKLCEFSRRPLVLTCKDLSLVPSELIALASEQNSLFHTKKISTSTVYAFLTKYLKSLEIEVCDDWLRDVVKQNNADIRKCLMHLQFWCVDTEADLISSKNRLPVLTSTLGSSVKDISQLTDLLSINDVIGQATLNRSMVRQEIDSTTMTPEKVNTFQDQNLDDEMKLKFDYVIDYKLHLNDPNRQPLLPFELNIYQHIQEQLEARYSYVREANHRLDNEYLVNRFKKMTESTLNFLASRIPKYDHLQSARRTRNSKKISDILNQFKGIYNDETLNENAEIDLLSATTQQIKAEINPFVFEIAKSDANVKNENKQIFELHSENVSERRYKDLVYQLSQEGVLKNVWFNADPSIVVRKWEHLHSGFSKNK", "output": "Involved in the negative control of telomere length and in telomeric silencing through a replication-mediated pathway. May have a role in Okazaki fragment maturation. Required for S-phase progression. Component of the RFC-like ELG1-RFC complex which appears to have a role in DNA replication, replication fork re-start, recombination and repair."}]}
+{"id": "function_test_224", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MHRTYSLRNQRAPTAAELQAPPPPPSSTKSKFFGKASIASSFRKNAAGNFGPELARKLSQLVKTEKGVLRAMEVVASERREAAKQLSLWGADNDDDVSDVTDKLGVLIYELGELQDQFIDKYDQYRVTLKSIRNIEASVQPSRDRKEKITDEIAHLKYKDPQSTKIPVLEQELVRAEAESLVAEAQLSNITREKLKAAYSYMFDSLRELSEKFALIAGYGKALLELLDDSPVTPGEARPAYDGYEASRQIIMDAESALESWTLDMAAVKPTLSFHQTVDDVYEDEDGEEEEEPEIQNGDIPGQVVEEEEVEWTTEVPVDDEAHEADHHVSQNGHTSGSENI", "output": "Together with PIL1, main component of eisosomes, structures at the cell periphery underneath the plasma membrane that mark the site of endocytosis. Negative regulator of cell wall integrity (CWI) in unstressed cells, probably by inhibiting protein kinase PKH1/PHK2 activity and regulating their downstream CWI pathways PKC1-MAP kinase pathway and protein kinase YPK1 pathway. Activity may be regulated by the transient increase of sphingolipid long chain bases (LCBs) during heat stress."}]}
+{"id": "function_test_225", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTSLFDALSRSNDRLPSPNFLPEDFLELLKSNDFDTKLTTLIRAATIAKREEDWFHKFQKKGELFKCIDKIICDDRWELQHQCIKFLVEAMPTFGSATEYCMCFVMPNLIPKLVSNKVTVRKITHQAIATFLRLKPEALQSFLKMLSNFMPNCNSKSELITELHHILIPELVKSNWTCLVENFTTESNIQGCEDQAGVLMKKLHYFIGNEFWQKIITNLSPEKREVLEQITANVQVEHTESKAGSGVLRASAKPQSGGERRLRFGIVPSLVCALIAEDTDANQRISGLEKMKQVVDQITPEEIARLVPHLHSYLLMLSNVLEDLNFKVVVLALDIVRATGHHLKGHMEAHIQQFVNLVAKHFGNQKSVIKQIIMMTFMELFQNINPKTVGGCLRVFLENKNSRVREEVINIYTASLMTISPSKFNLQPLVNILVPMFHDVKKRVRLAAFEQLSVLAYLLNGKTEIIMKPVRDFEQDQNSRGLTEAVTARIRRQVLPRIRYDGLIEYSTPPMMDSFDLAEAEMSLPSNADLSWIVSNGGVEPDPFERTMSPISLAGNLATIRRNRVIQQQGQAEKPSFSLPQQPAQQASHQAQRLPNGIEKSHETSENSSLDIGQRIVMTRMKSDDSFVRRQGSAASNPNSSTSSWEAPKRPPISPSEKSSISATKKEVNNNHIVKKGNLKSMRARSDTNLSEDHGEEEMENDPPRSFDDRPAKASGQYSFQDFDAAIVPSSMGKKSISHHSLPITSHPPLKHAISQPQKRINNNGTFLRSGQGQRTKSVSKPHRELTAVSKTYSLLDTSNMSVNQALKKMSSDEWADKVDGLNMISTLSETQPRMVADNLKEVIIAILNECKNLRSSVSRVAIVTIGTVAQNLNSKIDSEMEKICAVLLSKSGDVSNAFIRDDATDSLNKLVKAATAGKALQGIILAGAKSKNNTIRSSCANFVYDIITIQGSSAILNNQNALSNVLPVLLQFSRDQSPQVRNPGKQSLCFLSKDPNFDRLMRKNALESEIKAVKDVLANVEKRGGVDSLESTANLSGSLSRIGSTRRVQKKLPDSLQLDLDEIRTELLAAGWERRLTGLQRFEEMCGHASKAVASDTRLIEAFISRLGDTNGKVASCAMETYISTMGSMAKLYSTESNLKAVMNQLAHALTAHLSSKSEEHKHLARTCIQHTIRSIEPVSLLPAMTSATKKSNVKQRPFILTQYCELSKLAYKSKPKQVEVMALPLLWDSVKNSAPDVDNKKATQYLAKTLAKLIGEKQLLDLATSELDPNRKKQLDALIR", "output": "Required for normal structure and function of sensory cilia on amphid neurons, especially for the formation of distal ciliary structures, but is less important for normal assembly of middle and basal ciliary structures. Plays a role in the organization of axoneme microtubule bundles in sensory cilia. Required for normal structure and function of the ASER neuron that mediates attraction to NaCl. Required for normal chemotaxis to NaCl . Required for normal avoidance response to high osmolarity. In contrast, is not required for normal chemotaxis to isoamyl alcohol. Does not play a role in intraflagella transport (IFT) . Promotes dauer formation in response to pheromones such as the ascarosides ascr#2, ascr#3, ascr#5, ascr#8 and icas#9 ."}]}
+{"id": "function_test_226", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKLKLTVLLILVHASASYKPPAIEVEDYQVQEHDSIGKFVELEEHTRLILKCSAHHNGDLKYNFPSMEGNVGYDENNFKKRMEEYYDDAFGDKVLTLNDVRESDTGTYSCSSMEHSSLNDTIYVFVHRKKVFLPLKSVMIIYKQGEVMVPCKTTKFVDKSDIELYASNVLVKEASKYNYDQRYGFKITKKLYSEKQIVDVNFECRYKKEENQTATYIITEKEASSDDGYHFSWEKGFQWPHVGYNFSLTCNLNYNGSKIFHGYTNKLSIECPQCSHDPGSHVHVDRHRIIGNKISTTVRIQHLELEDSGKYTCIWEHENKETKYTDYHLYVAPKKAQIKVIETSPTIMRIKENRATSLTAKFAIYPFEKESYTAKWSRIYNSSIHEGPQSETIINDDFRKIAATSFGDGAFSENLDIKAFAVSTNMSGTYVLSISHMDTVQVVQWEVAIENDEPDVQITVREPSSFFISNQEYYKPDTNLHIECISISIPPADVVFEYKTKNSEQFQEIEPNKLVSVGGTFDRGLIYNVTFTEGMDLKCSSIRKGNRAITVNKLIKIGEGFEVRPHHEKSSKATESEPSKIIYEGDNVKLTCVFPLDSDDWSVSWRFENSKSSDISSIPTTTETEIKQYSKHLILNLRDVTTSFTGTYTCVVKNEDSEKLLETSIDVKAISKPSITGGNSNAVVIVDYDQYFEINCNMTGTPPPVYQWFKDGNPYTHGDVDGSILRVSRARGEDDGEFHCLATNRAGDKLNSIEVQVNNAPKGSLFFYWFLALLLLISIIAVFLLTCKLRASNRLTKQKDIALNTLYETMIKHQAGPLPEEMKDLPVEERTYYLPYNNDYEIDPVNLEILNPIGSGHFGVVKKGLLGMAYPKSKIESKTRLPVAVKSSTNPFNVELQKMMAEELKVMCAIPKNPNVLALIGAVTKNMRQGQLYIVTEFIDGGNLREFLQAHRNTFINELVEDEHVPVDDSYLVPNSVKKKIYKFDEKLGEGTRLLVEDPDALCTSDLLSIGLQIAKGMAWLADVPCVHRDLACRNVLITKTKIVRIADFGLSKKHTNKTYYRTKKSKDTPLPVRWMPLECIEEFKFTQKSDVWSFGICLYEIFTLGGTPYPNCDTFNVIEFIRNGNRNKQPEYCHDEIYELMKVCWQFNPKDRPTFNDCITFFENHMRDSSSQFLERVENMLHTEMQEQSKLDDWIQDSRPDVPNVSFQKSPKKQKEERYLIVESHA", "output": "Receptor tyrosine kinase which may be involved, downstream of pvf-1, in the positioning of ray 1, the most anterior ray sensillum in the male tail."}]}
+{"id": "function_test_227", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGYDDRERDRERRRHRSRSRDRHRERSRDRRHHRNSRRKPSLYWDVPPPGFEHITPMQYKAMQASGQIPASVVPDTPQTAVPVVGSTITRQARRLYVGNIPFGVTEEEMMEFFNQQMHLVGLAQAAGSPVLACQINLDKNFAFLEFRSIDETTQAMAFDGINLKGQSLKIRRPHDYQPMPGITDTPAIKPAVVSSGVISTVVPDSPHKIFIGGLPNYLNDDQVKELLLSFGKLRAFNLVKDAATGLSKGYAFCEYVDLSITDQSIAGLNGMQLGDKKLIVQRASVGAKNAQNAANTTQSVMLQVPGLSNVVTSGPPTEVLCLLNMVTPDELRDEEEYEDILEDIKEECTKYGVVRSVEIPRPIEGVEVPGCGKVFVEFNSVLDCQKAQQALTGRKFSDRVVVTSYFDPDKYHRREF", "output": "Necessary for the splicing of pre-mRNA. Binds to the polypyrimidine tract of introns early during spliceosome assembly (By similarity)."}]}
+{"id": "function_test_228", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEGRNAAAEPFVWVNSASAHSQSVAKAKYEFLFGKSEEKTPDSSDHGGSTLLPPTVTNEFPEYGTMEEGGEGLRASLDFDAKSPPCRLPGQQAVHLLAGQDSILNSVTEGPNDAPQCHPQEQSLQPIDSLISALKATEARIASGTFQATKVLDKDANFSVYQVDKELSTASHKPQRAHRTFPVGPGKSPDIPLSAEVPTEENLSLHIQEDLSALLPEEAQAHRSQITNYRRQGPLRVPESACPVSSSSAGSHNPVDRVGALREQRSDLGREHPRGYDRGGSMGRQGRIKHVEFQGVEILWTGEEAESRHPPERTASPVSKEFAKRPSHSSPACGVCSTSTHLTGDVWDETCKAPSERPGTSAGTLSPMPLGESGEDDVFLRESKEHLEENFAIQGDKERILDQEEHLRGDDDILGPGYTEDSTDVYSSQFETILDNTSLYYSAESLETLYSEPDSYFSFEMPLTPMIQQRIKEGGQFLERTSVGGQHDVLSVSADGGIVMGYSAGITNGLHDSANSVYTRGPQEIAFWGSRDRCFAEGKTTGVDAGSEMGSTDILEKETTESLSNGTNSNVEAAKRLAKRLYHLDRFKRSDVAKHLGKNNEFSKLVAEEYLKFFDFTGMTLDQSLRYFLKAFSLVGETQERERVLIHFSNRYFSCNPDTITSKDGVHCLTCAMMLLNTDLHGHVNIGKKMTCQEFITNLQGVNEGGDFSKDLLKALYNSIKNEKLEWAVDDEEKKKSPSEGTDEKANGTHPKTISRIGSTTNPFLDIPHDPNAAVYKSGFLARKIHADMDGKKTPRGKRGWKTFYAVLKGTVLYLQKDEYKPEKSLSDEDLKNAVSVHHALASKATDYEKKPNVFKLKTADWRVLLFQTQSPEEMQGWINKINCVAAVFSAPPFPAAIGSQKKFSRPLLPATTTKLSQEEQLKSHESKLKQITTELAEHRSYPPDKKVKAKDVDEYKLKDHYLEFEKTRYEIYVSVLKEGGKELLTTDGNEPVGLKKSHSSPSLNPDASPVTAKVKRNVSERKDHRPETPGIKQKVT", "output": "Guanine nucleotide exchange factor for ARF6."}]}
+{"id": "function_test_229", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRRGWKMALSGGLRCCRRVLSWVPVLVIVLVVLWSYYAYVFELCLVTVLSPAEKVIYLILYHAIFVFFAWTYWKSIFTLPQQPNQKFHLSYTDKERYKNEERPEVQKQMLVDMAKKLPVYTRTGNGAVRFCDRCHLIKPDRCHHCSVCAMCVLKMDHHCPWVNNCIGFSNYKFFLQFLAYSVLYCLYIATTVFSYFIKYWRGELPSVRSKFHVLFLLFVACMFFVSLVILFGYHCWLVSRNKTTLEAFCTPVFTSGPEKNGFNLGFIKNIQQVFGDNKKFWLIPIGSSPGDGHSFPMRSMNESQNPLLANEEPWEDNEDESQDYPEGLSSLAVESET", "output": "Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates (By similarity). Has no stringent fatty acid selectivity and in addition to palmitate can also transfer onto target proteins myristate from tetradecanoyl-CoA and stearate from octadecanoyl-CoA (By similarity). Palmitoylates IGF2R and SORT1, promoting their partitioning to an endosomal membrane subdomain where they can interact with the retromer cargo-selective complex (By similarity). Thereby, regulates retrograde transport from endosomes to the Golgi apparatus of these lysosomal sorting receptors and plays a role in trafficking of lysosomal proteins (By similarity). In the nervous system, catalyzes the palmitoylation of DLG4/PSD95 and regulates its synaptic clustering and function in synaptogenesis . Could be involved in the differentiation of dopaminergic neurons and the development of the diencephalon (By similarity). Could also catalyze the palmitoylation of GAP43 (By similarity). Could also palmitoylate DNAJC5 and regulate its localization to the Golgi membrane (By similarity). Could also palmitoylate FYN as shown in vitro (By similarity)."}]}
+{"id": "function_test_230", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAEFRDDQASRLCDNCKKEIPVFNFTIHEIHCQRNIGVCPVCKEPFPKSDMDIHMAAEHCQVTCKCNKKLEKRQLKQHAETECPLRLAVCQHCDLELSVVKLKEHEDYCGARTELCGSCGRNVLVKELKTHPEVCGRVEEEKRTEAAIPPEAYDEPWSQDRIWIASQLLRQIEALDPPMRLPGRPLQAFEADPFYSRTTSQRSMAAQFPVQNNLFEEQERQERNRSRQSPKDSAENNAHLDFMLALSLQNEGQATSMVEQGFWESVPEADPARAGPTSLGDIKGAADEILLPCEFCEELYPEELLIDHQTSCNPSHALRSLNTGSSSIRGVEDPGTIFQNFLQQATSNQFDTLMGLSSSAAVEDSIIIPCEFCGVQLEEEVLFYHQDQCDQRPATANHRAVEGIPAQDSQPENTSAELSRRRVKHQGDLSSGYMDDVKPESVKGPTYSMSPNRTMNNVASCNRLLNLPSGPRSDCQRSPPGVLKLNNSDSQDIRGQMRGSQNGPIASGHAPVIHSIQNLYPENFAPSFPHGSPGRYGAGGRSEGGRSSRVSPAAAGYHSRAAKAKPPKQQGAGDAEEEEE", "output": "Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3."}]}
+{"id": "function_test_231", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREEQMASIKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDAPSQPVNNHHAHSHTPVEKRKYNPTSHHTATDHIPEKKFKSEALLSTLTSDASKENTLGCRNNNSTASCNNAYNVNSSQPLASYNIGSLSSGAGAGAITMAAAQAVQATAQMKEGRRTSSLKASYEAFKNNDFQLGKEFSMPRETAGYSSSSALMTTLTQNASSSAADSRSGRKSKNNTKSSSQQSSSSSSSSSSSSLSLCSSSSTVVQEVSQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWFCPQCTAAMKRRGSRHK", "output": "Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AZ1 from the nucleosome (By similarity)."}]}
+{"id": "function_test_232", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGSISEMVFETCPSPNPIHVMLVSFQGQGHVNPLLRLGKLIASKGLLVTFVTTELWGKKMRQANKIVDGELKPVGSGSIRFEFFDEEWAEDDDRRADFSLYIAHLESVGIREVSKLVRRYEEANEPVSCLINNPFIPWVCHVAEEFNIPCAVLWVQSCACFSAYYHYQDGSVSFPTETEPELDVKLPCVPVLKNDEIPSFLHPSSRFTGFRQAILGQFKNLSKSFCVLIDSFDSLEQEVIDYMSSLCPVKTVGPLFKVARTVTSDVSGDICKSTDKCLEWLDSRPKSSVVYISFGTVAYLKQEQIEEIAHGVLKSGLSFLWVIRPPPHDLKVETHVLPQELKESSAKGKGMIVDWCPQEQVLSHPSVACFVTHCGWNSTMESLSSGVPVVCCPQWGDQVTDAVYLIDVFKTGVRLGRGATEERVVPREEVAEKLLEATVGEKAEELRKNALKWKAEAEAAVAPGGSSDKNFREFVEKLGAGVTKTKDNGY", "output": "UDP-glucosyltransferase that forms glucose esters with phenylpropanoids . Glucosylates 4-coumarate, ferulate, caffeate, sinapate and cinnamate . Can glucosylate the phytotoxic xenobiotic compound 2,4,5-trichlorophenol (TCP) ."}]}
+{"id": "function_test_233", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MALPASLLPLCCLALLALSAQSCGPGRGPVGRRRYVRKQLVPLLYKQFVPSMPERTLGASGPAEGRVTRGSERFRDLVPNYNPDIIFKDEENSGADRLMTERCKERVNALAIAVMNMWPGVRLRVTEGWDEDGHHAQDSLHYEGRALDITTSDRDRNKYGLLARLAVEAGFDWVYYESRNHIHVSVKADNSLAVRAGGCFPGNATVRLRSGERKGLRELHRGDWVLAADAAGRVVPTPVLLFLDRDLQRRASFVAVETERPPRKLLLTPWHLVFAARGPAPAPGDFAPVFARRLRAGDSVLAPGGDALQPARVARVAREEAVGVFAPLTAHGTLLVNDVLASCYAVLESHQWAHRAFAPLRLLHALGALLPGGAVQPTGMHWYSRLLYRLAEELMG", "output": "[Desert hedgehog protein]: The C-terminal part of the desert hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (DhhN and DhhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated DhhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Functions in cell-cell mediated juxtacrine signaling (By similarity). Promotes endothelium integrity . Binds to PTCH1 receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes in endothelial cells . In Schwann cells, controls the development of the peripheral nerve sheath and the transition of mesenchymal cells to form the epithelium-like structure of the perineurial tube .; "}]}
+{"id": "function_test_234", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNAKFREFLEAQDDYEPSWSLQDKYSSRAAALFRDKVATLAEGKEWSLESSPAQNWTPPQPKTLQFTAHRPAGQPQNVTTSGDKAFEDWLNDDLGSYQGAQENRYVGFGNTVPPQKREDDFLNSAMSSLYSGWSSFTTGASKFASAAKEGATKFGSQASQKASELGHSLNENVLKPAQEKVKEGRIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEDTSDRPLEGHSYQNSSGDNSQNSTIDQSFWETFGSAEPPKAKSPSSDSWTCADASTGRRSSDSWDIWGSGSASNNKNSNSDGWESWEGASGEGRAKATKKAAPSTAADEGWDNQNW", "output": "GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine."}]}
+{"id": "function_test_235", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MATVPELNCEIAAFDSEENDLFFEADRPQKIKDCFQALDLGCPDESIQLQISQQHLDKSFRKAVSLIVAVEKLWQLPMSCPWSFQDEDPSTFFSFIFEEEPVLCDSWDDDDLLVCDVPIRQLHCRLRDEQQKCLVLSDPCELKALHLNGQNISQQVVFSMSFVQGETSNDKIPVALGLKGLNLYLSCVMKDGTPTLQLESVDPKQYPKKKMEKRFVFNKIEVKTKVEFESAQFPNWYISTSQAEHRPVFLGNSNGRDIVDFTMEPVSS", "output": "Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore."}]}
+{"id": "function_test_236", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGSVRTNRYSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDASKESKACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHCYKVDYSRFHKTYEVPNTPLCSARDLAEKKYILSNANSFCYENEVALTSKEEEDSENGVPESTSTDSPPGIDLHNQASVPLEPRPLRRESEI", "output": "Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity)."}]}
+{"id": "function_test_237", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGRAKSMVSLLLVLFLVRAHVATTETTTEFIFHGFKGNQSEIHMQGDSTITSNGLLRLTDRNSDVVGTAFYHKPVRLLDSNSTNTTVRSFSTSFIFIIPSSSTSNGGFGFTFTLSPTPNRTDADPEQYMGLLNERNDGNSSNHVFAVEFDTVQGFKDGTNRIGNHIGLNFNSLSSDVQEPVAYFNNNDSQKEEFQLVSGEPIQVFLDYHGPTKTLNLTVYPTRLGYKPRIPLISREVPKLSDIVVDEMFVGFTAATGRHGQSSAHYVMGWSFASGGEHPLAAMLDISQLPPPPPNKAKKRGYNGKVIALIVALSTVISIMLVLLFLFMMYKKRMQQEEILEDWEIDHPHRFRYRDLYKATEGFKENRVVGTGGFGIVYRGNIRSSSDQIAVKKITPNSMQGVREFVAEIESLGRLRHKNLVNLQGWCKHRNDLLLIYDYIPNGSLDSLLYSKPRRSGAVLSWNARFQIAKGIASGLLYLHEEWEQIVIHRDVKPSNVLIDSDMNPRLGDFGLARLYERGSQSCTTVVVGTIGYMAPELARNGNSSSASDVFAFGVLLLEIVSGRKPTDSGTFFIADWVMELQASGEILSAIDPRLGSGYDEGEARLALAVGLLCCHHKPESRPLMRMVLRYLNRDEDVPEIHDNWGYSDSSRTDLGSKLVGYISSDRASSSHSHTSSSLTRISSTSLISGR", "output": "Involved in negative regulation of abscisic acid response in seed germination."}]}
+{"id": "function_test_238", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MESIGSHCCSSPFTFITRNSSSSLPRLVNITHRVNLSHQSHRLRNSNSRLTCTATSSSTIEEQRKKKDGSGTKVRLNVRLDHQVNFGDHVAMFGSAKEIGSWKKKSPLNWSENGWVCELELDGGQVLEYKFVIVKNDGSLSWESGDNRVLKVPNSGNFSVVCHWDATRETLDLPQEVGNDDDVGDGGHERDNHDVGDDRVVGSENGAQLQKSTLGGQWQGKDASFMRSNDHGNREVGRNWDTSGLEGTALKMVEGDRNSKNWWRKLEMVREVIVGSVEREERLKALIYSAIYLKWINTGQIPCFEDGGHHRPNRHAEISRLIFRELEHICSKKDATPEEVLVARKIHPCLPSFKAEFTAAVPLTRIRDIAHRNDIPHDLKQEIKHTIQNKLHRNAGPEDLIATEAMLQRITETPGKYSGDFVEQFKIFHNELKDFFNAGSLTEQLDSMKISMDDRGLSALNLFFECKKRLDTSGESSNVLELIKTMHSLASLRETIIKELNSGLRNDAPDTAIAMRQKWRLCEIGLEDYFFVLLSRFLNALETMGGADQLAKDVGSRNVASWNDPLDALVLGVHQVGLSGWKQEECLAIGNELLAWRERDLLEKEGEEDGKTIWAMRLKATLDRARRLTAEYSDLLLQIFPPNVEILGKALGIPENSVKTYTEAEIRAGIIFQISKLCTVLLKAVRNSLGSEGWDVVVPGSTSGTLVQVESIVPGSLPATSGGPIILLVNKADGDEEVSAANGNIAGVMLLQELPHLSHLGVRARQEKIVFVTCDDDDKVADIRRLVGKFVRLEASPSHVNLILSTEGRSRTSKSSATKKTDKNSLSKKKTDKKSLSIDDEESKPGSSSSNSLLYSSKDIPSGGIIALADADVPTSGSKSAACGLLASLAEASSKVHSEHGVPASFKVPTGVVIPFGSMELALKQNNSEEKFASLLEKLETARPEGGELDDICDQIHEVMKTLQVPKETINSISKAFLKDARLIVRSSANVEDLAGMSAAGLYESIPNVSPSDPLVFSDSVCQVWASLYTRRAVLSRRAAGVSQREASMAVLVQEMLSPDLSFVLHTVSPADPDSNLVEAEIAPGLGETLASGTRGTPWRLASGKLDGIVQTLAFANFSEELLVSGTGPADGKYVRLTVDYSKKRLTVDSVFRQQLGQRLGSVGFFLERNFGCAQDVEGCLVGEDVYIVQSRPQPL", "output": "Mediates the incorporation of phosphate into starch-like phospho-alpha-glucan, mostly at the C-3 position of glucose units. Required for starch degradation, suggesting that the phosphate content of starch regulates its degradability."}]}
+{"id": "function_test_239", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAAAAPSRVSVRAAAPGQTGGFAKIRPQVVVAAAARSAGVSGRRARSVRASLFSPKPATPKDARPAKVQEMFVYEINERDRESPAYLRLSAKQTENALGDLVPFTNKLYSGSLDKRLGISAGICILIQHVPERNGDRYEAIYSFYFGDYGHISVQGPYLTYEESYLAVTGGSGVFEGAYGQVKLNQIVFPFKIFYTFYLKGIPDLPRELLCTPVPPSPTVEPTPAAKATEPHACLNNFTN", "output": "Involved in the production of 12-oxo-phytodienoic acid (OPDA), a precursor of jasmonic acid (JA) . Required for the production of JA in response to wounding . Necessary for flower and coleoptile development regulation by light, including blue (BL), red (RL) and far red (FR) lights . Involved in the auxin-mediated signaling pathway leading to growth stimulation . Essential for photodestruction of phyA upon activation by RL and FR . Implicated in responses to salt stress (NaCl) .; "}]}
+{"id": "function_test_240", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAAGGNRDGEKRGSRSQADSGFLGLRPTSVDPALRRRRRGPRNKKRGWRRLAEEPLGLEVDQFLEDVRLQERTTGGLLAEAPNEKLFFVDTGFKRKEPRKKRTLVQKKSQRLQKPLRVDLALENHSKIPAPKDILAHQVPNAKKLRRKEELWEKLAKQGELPRDVRKAQARLLSPPTPKAKPGPQDIIERPFYDLWNPDNPLDTPLIGQDAFFLEQTKKKGVRRPQRLHIKPSQVPAVEVIPAGASYNPTFEDHQALLREAHEVELQREKEAEKLERQLALPTSEQAATQESVFREMCEGLLEESDGEDEHEAGRAGQPEAGDGTTEISPTGAAGPEKRMEKKTEQQRRREKAARKLRVQQAALRAARLQHQELFRLRGIKAQVARRLAELARRREQRRIRRLAEADKPRRLGRLKYQAPDIDVQLSSELSGSLRTLKPEGHILRDRFKSFQKRNMIEPRERAKFKRKYKVKLVEKRAYREIQL", "output": "Nucleolar protein which is involved in the integration of the 5S RNP into the ribosomal large subunit during ribosome biogenesis. In ribosome biogenesis, may also play a role in rRNA transcription (By similarity). Also functions as a nucleolar sensor that regulates the activation of p53/TP53 in response to ribosome biogenesis perturbation, DNA damage and other stress conditions. DNA damage or perturbation of ribosome biogenesis disrupt the interaction between NOP53 and RPL11 allowing RPL11 transport to the nucleoplasm where it can inhibit MDM2 and allow p53/TP53 activation . It may also positively regulate the function of p53/TP53 in cell cycle arrest and apoptosis through direct interaction, preventing its MDM2-dependent ubiquitin-mediated proteasomal degradation. Originally identified as a tumor suppressor, it may also play a role in cell proliferation and apoptosis by positively regulating the stability of PTEN, thereby antagonizing the PI3K-AKT/PKB signaling pathway. May also inhibit cell proliferation and increase apoptosis through its interaction with NF2. May negatively regulate NPM1 by regulating its nucleoplasmic localization, oligomerization and ubiquitin-mediated proteasomal degradation. Thereby, may prevent NPM1 interaction with MYC and negatively regulate transcription mediated by the MYC-NPM1 complex. May also regulate cellular aerobic respiration. In the cellular response to viral infection, may play a role in the attenuation of interferon-beta through the inhibition of RIGI (By similarity)."}]}
+{"id": "function_test_241", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MMFRTSLMRFAAAFFAIVFVVLVGVARSEECTRTCIAQNCDTLSIRYGKYCGIGHSGCPGEEPCDDLDACCKIHDHCVELNGMTNISCHKKFQRCVNRLSKAIKQSKNKKVGFSTKCPYSVVIPTVNQGMDIGILFSQLGNDMKTEL", "output": "PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Releases lysophospholipids (LPLs) and free fatty acids (FFAs) from membrane phospholipids in response to hormones and other external stimuli. Regulates the process of cell elongation and plays important roles in shoot gravitropism by mediating auxin-induced cell elongation. Involved in stomatal opening in response to light. Plays a role in pollen development and germination and tube growth."}]}
+{"id": "function_test_242", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLLKFEASSELRLVDPSVSLTVLRKIRLSHLPDMTMTSESSGKKCGEGDGKVAGKSQRKVGLVYDETMCKHDTPNGKVDVECPDRIRVIWEKLQLAGVTQRCVVLGGSKAEDKHLKLVHTKKHVNLVKSISTKKKDSRRNKIASQLDSIYLNGGSSEAAYLAAGSVVKVAEKVAEGELDCGFAIVRPPGHHAESDEAMGFCLFNNVAVAASFLLNERPDLDVKKILIVDWDIHHGNGTQKMFWKDSRVLIFSVHRHDHGSFYPFGDDGDFNMVGEGPGEGFNINVPWEQGGCGDADYLAVWNHILIPVTKEFKPDIILLSAGFDAAIGDPLGGCCVTPYGYSVMLKKLMEFAHGKIVLALEGGYNLESLGKSSLACVQVLLEDKQIHGSSETYPLESTRRVIQAVRERLCTYWPSLDASMASNENLKNPSAERNSADALLREVEELKSLMAARDGELEARRKELKAKNKELEANEKELEAGLMLIRAREDVICGLHAKIESLQQERDEAVAKAERIDKELQEDRARSQEFKEDTEFCLSTLRREKELAIMAKNKDLEAKEKELEARLMLVHAREDKIHAKIERLQQERDEAVAKAERIDKELQEDRSRSRVGNGSFAFSQEFYEDMDLDELEPLSPEFNEDMDSEELEPFQVIKKNMERSHKKFIKDMECIKFIASERARVL", "output": "Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (Probable). Histone deacetylases act via the formation of large multiprotein complexes (Probable). Required for appropriate cellular patterning in the root epidermis . Involved in the differentiation of hair and non-hair cells in the root epidermis . Is not directly involved in the regulation of the expression of pattern genes . Regulates the transcription of certain kinase genes, which are components of a positional information relay system, by changing their histone acetylation status ."}]}
+{"id": "function_test_243", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDDIDSSDGAAAARAGEIGSIGVSTPWKPIQLVFKRYLPQNGSASKVHVAVKKPVVVRLTRDLVETYKICDPQFKYRGELNPKRYLTTPSVGVNNDGFDNVNYDLILAVNDDFCSSDSRQRYIVKDLLGHGTFGQVAKCWVPETNSFVAVKVIKNQLAYYQQALVEVSILTTLNKKYDPEDKNHIVRIYDYFLHQSHLCICFELLDMNLYELIKINQFRGLSLSIVKLFSKQILLGLALLKDAGIIHCDLKPENILLCASVKPTEIKIIDFGSACMEDKTVYSYIQSRYYRSPEVLLGYQYTTAIDMWSFGCIVAELFLGLPLFPGGSEFDILRRMIEILGKQPPDYVLKEAKNTNKFFKCVGSVHNLGNGGTYGGLKSAYMALTGEEFEAREKKKPEIGKEYFNHKNLEEIVKSYPYKINLPEDDVVKETQIRLALIDFLKGLMEFDPAKRWSPFQAAKHPFITGEPFTCPYNPPPETPRVHVTQNIKVDHHPGEGHWFAAGLSPHVSGRTRIPMHNSPHFQMMPYSHANSYGSIGSYGSYNDGTIQDNSYGSYGGTGNMFAYYSPVNHPGLYMQNQGGVSMLGTSPDARRRVMQYPHGNGPNGLGTSPSAGNFAPLPLGTSPSQFTPNTNNQFLAGSPGHHGPTSPVRNSCHGSPLGKMAAFSQINRRMSAGYSGGSQSQDSSLSQAQGHGMDNFYQNEGYSGQFSGSPSRRQLDSGVKNRKQTQGGTTLSTGYSTHNNANSSLRSNMYNPSSTAHHLENPDTALSVPDPGDWDPNYSDDLLLEEDSADESSLANAFSRGMQLGSTDASSYSRRFNSNASTSSSNPTTQRRYAPNQAFSQVETGSPPSNDPHARFGQHIPGSQYIPHVSQNSPSRLGQQPPQRYNHGRPNAGRTMDRNHMNAQLPPSNTNSGGQQRSPRSSSYTNGVPWGRRTNNHVPNVPSTSHGRVDYGSIA", "output": "Dual specificity protein kinase that phosphorylates ANN1, ANN2 and CP29B at serine and threonine residues, and ANN1, ANN2 and ANN4 at tyrosine residues. May regulate the phosphorylation status of annexin proteins . Acts as positive regulator in abscisic acid (ABA)-mediated regulation of postgermination growth and drought response. May regulate the expression of ABA-responsive genes such as RD22, RD29A, LTI65/RD29B and RAB18 ."}]}
+{"id": "function_test_244", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPKTVVVTHPGKPINNEKRFRFELLYFCVILLMVVGLAAGYFMWMMSFSTHSPNKGLHILDRSEWLGEPPSGKYPHLKLPVSNIIIHHTATEGCEQEDVCIYRMKTIQAFHMKSFGWVDIGYNFLVGGDGQIYVGRGWHIQGQHVNGYGAISVSIAFIGTFVNMEPPARQIEAAKRLMDEGVRLHRLQPDYHIYAHRQLSPTESPGQKLFELMQNWPRFTQDPTSLRLLSNETVKIVTRPYWLAQPPIVPLTPLKLPIESVRFVATNTPSCFTQAECTFRVRLLQNWHIESNGYKDINYNFVAAGDENIYEARGWDHSCEPPKDADELVVAFIGPSSSNKKIALELIKQGIKLGHISKNYSLIDDLEKS", "output": "Peptidoglycan-recognition protein probably involved in innate immunity by binding to peptidoglycans (PGN) of bacteria and activating the immune response."}]}
+{"id": "function_test_245", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPAESGKRFKPSKYVPVSAAAIFLVGATTLFFAFTCPGLSLNVSPAVPIYNAIMFLFVLANFSMATFMDPGIFPRAEEDEDKEDDFRAPLYKTVEIKGIQVRMKWCATCRFYRPPRCSHCSVCDNCVEEFDHHCPWVNNCIGRRNYRYFFLFLLSLTAHIMGVFGFGLLYVLYHIEELSGVRTAVTMAVMCVAGLFFIPVAGLTGFHVVLVARGRTTNEQVTGKFRGGVNPFTNGCCNNVSRVLCSSPAPRYLGRPKKEKTIVIRPPFLRPEVSDGQITVKIMDNGIQGELRRTKSKGSLEITESQSADAEPPPPPKPDLSRYTGLRTHLSLATNEDSSLLGKDSPPTPTMYKYRPGYSSSSTSAAMPHSSSAKLSRGDSLKEPTSIADSSRHPSYRSEPSLEPESFRSPTFGKSFHFDPLSSGSRSSSLKSAQGTGFELGQLQSIRSEGTTSTSYKSLANQTRNGSLSYDSLLTPSDSPDFESVQAGPEPDPPLGYTSPFLSARLAQQREAERHPRLLPTGPPHREPSPVRYDNLSRHIVASLQEREKLLRQSPPLAGREEEPGLGDSGIQSTPGSGHAPRTSSSSDDSKRSPLSKTPLGRPAVPRFGKPDGLRSRGLGSPEPGTTAPYLGRSISYSSQKAPSGVSETEEVALQPLLTPKDEVQLKTTYSKSNGQPKSIGSASPGPGQPPLSSPTRGGVKKVSGVGGTTYEISV", "output": "Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates such as CTNND2, CD36, STAT3 and S1PR1 thus plays a role in various biological processes including cell adhesion, fatty acid uptake, bacterial sensing or cardiac functions . Plays an important role in the regulation of synapse efficacy by mediating palmitoylation of delta-catenin/CTNND2, thereby increasing synaptic delivery and surface stabilization of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (AMPARs) . Under basal conditions, remains at the synaptic membrane through FYN-mediated phosphorylation that prevents association with endocytic proteins. Neuronal activity enhances the internalization and trafficking of DHHC5 from spines to dendritic shafts where it palmitoylates delta-catenin/CTNND2. Regulates cell adhesion at the plasma membrane by palmitoylating GOLGA7B and DSG2. Plays a role in innate immune response by mediating the palmitoylation of NOD1 and NOD2 and their proper recruitment to the bacterial entry site and phagosomes. Participates also in fatty acid uptake by palmitoylating CD36 and thereby targeting it to the plasma membrane . Upon binding of fatty acids to CD36, gets phosphorylated by LYN leading to inactivation and subsequent CD36 caveolar endocytosis. Controls oligodendrocyte development by catalyzing STAT3 palmitoylation ."}]}
+{"id": "function_test_246", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MATEHNVQLVPGSQKIPKGVVSPRSAAEGPALTRRRSKKESWHPGSQKASSGDQSSSQGSEASGSSKHPPRTKVGQEEPSSAPARPASHRHSHRHRSDPQQDAAQRTYGPLLNRMFGKDRELGPEELEELQAAFEEFDTDQDGYIGYRELGDCMRTLGYMPTEMELLEVSQHVKMRMGGFVDFEEFVELISPKLREETAHMLGVRELRIAFREFDKDRDGRITVAELRQAAPALLGEPLEGTELDEMLREMDLNGDGTIDFDEFVMMLSTG", "output": "Involved in normal synaptic function through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1D and CACNA1F, suppressing the calcium-dependent inactivation and shifting the activation range to more hyperpolarized voltages."}]}
+{"id": "function_test_247", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEPRINDLQVESRVHELLDFPVHTNQISSAIYECPNDHIENPKKKPYNCPHSGAKCDVTGDIQRLLLHLRNDHNVEMSDGRSFSHRYVHHDPKHLHHATWMLTLLDCCGRKFCLYFEAFHLRKTPMYMAFMQFMGDEEEAMSFSYSLQVGGNGRKLTWQGVPRSIRDSHKTVRDSQDGLIITRKLALFFSTDNNTTDKELKLKVSGRVWREQPVSI", "output": "Probable inactive E3 ubiquitin-protein ligase that plays a role in regulation of autophagy. Upon starvation, involved in maintaining ATG6 homeostasis by competitively associating with ATG6, a component of the autophagosome complex . Acts as positive regulator of drought stress response. Functions as positive regulator of abscisic acid-mediated stomatal closure ."}]}
+{"id": "function_test_248", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAGNDWVNSYLEAILDVGQGLDDARSSPSLLLRERGRFTPSRYFVEEVITGYDETDLHRSWVKAVATRSPQERNTRLENMCWRIWNLARQKKQHEEKEAQRLAKRRLEREKGRREATADMSEEFSEGEKGDIISDISTHGESTKPRLPRINSAESMELWASQQKGNKLYLVLISLHGLIRGENMELGRDSDTGGQVKYVVELARALGSMPGVYRVDLLTRQVSSPDVDYSYGEPTEMLTPRDSEDFSDEMGESSGAYIVRIPFGPKDKYIPKELLWPHIPEFVDGAMSHIMQMSNVLGEQVGVGKPIWPSAIHGHYADAGDATALLSGALNVPMLLTGHSLGRDKLEQLLRQGRLSKEEINSTYKIMRRIEGEELSLDVSEMVITSTRQEIDEQWRLYDGFDPILERKLRARIKRNVSCYGRFMPRMVKIPPGMEFNHIVPHGGDMEDTDGNEEHPTSPDPPIWAEIMRFFSNSRKPMILALARPDPKKNITTLVKAFGECRPLRELANLALIMGNRDGIDEMSSTSSSVLLSVLKLIDKYDLYGQVAYPKHHKQSDVPDIYRLAAKSKGVFINPAIIEPFGLTLIEAAAHGLPMVATKNGGPVDIHRVLDNGLLVDPHDQQSISEALLKLVADKHLWAKCRQNGLKNIHQFSWPEHCKTYLSRITSFKPRHPQWQSDDGGDNSEPESPSDSLRDIQDISLNLKFSFDGSGNDNYMNQEGSSMDRKSKIEAAVQNWSKGKDSRKMGSLERSEVNSGKFPAVRRRKFIVVIALDFDGEEDTLEATKRILDAVEKERAEGSVGFILSTSLTISEVQSFLVSGGLNPNDFDAFICNSGSDLHYTSLNNEDGPFVVDFYYHSHIEYRWGGEGLRKTLIRWASSLNEKKADNDEQIVTLAEHLSTDYCYTFTVKKPAAVPPVRELRKLLRIQALRCHVVYSQNGTRINVIPVLASRIQALRYLFVRWGIDMAKMAVFVGESGDTDYEGLLGGLHKSVVLKGVSCSACLHANRSYPLTDVISFESNNVVHASPDSDVRDALKKLELLKD", "output": "Plays a major role in photosynthetic sucrose synthesis by catalyzing the rate-limiting step of sucrose biosynthesis from UDP-glucose and fructose- 6-phosphate. Involved in the regulation of carbon partitioning in the leaves of plants. May regulate the synthesis of sucrose and therefore play a major role as a limiting factor in the export of photoassimilates out of the leaf. Plays a role for sucrose availability that is essential for plant growth and fiber elongation. Required for nectar secretion."}]}
+{"id": "function_test_249", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MFLQFAVWKCLPHGILIASLLVVSWGQYDDDWQYEDCKLARGGPPATIVAIDEESRNGTILVDNMLIKGTAGGPDPTIELSLKDNVDYWVLLDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQCVNKKVGTVIYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQYNPEDPTSNDTFEIPLMLTGNVVLRKRLNYEDKTRYYVIIQANDRAQNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPILVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELTLLEPVNRDFHQKFDLVIKAEQDNGHPLPAFASLHIEILDENNQSPYFTMPSYQGYILESAPVGATISESLNLTTPLRIVALDKDIEDTKDPELHLFLNDYTSVFTVTPTGITRYLTLLQPVDREEQQTYTFLITAFDGVQESEPVVVNIRVMDANDNTPTFPEISYDVYVYTDMSPGDSVIQLTAVDADEGSNGEISYEILVGGKGDFVINKTTGLVSIAPGVELIVGQTYALTVQASDNAPPAERRHSICTVYIEVLPPNNQSPPRFPQLMYSLEVSEAMRIGAILLNLQATDREGDPITYAIENGDPQRVFNLSETTGILSLGKALDRESTDRYILIVTASDGRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVRATDPDAGINGQVHYSLGNFNNLFRITSNGSIYTAVKLNREARDHYELVVVATDGAVHPRHSTLTLYIKVLDIDDNSPVFTNSTYTVVVEENLPAGTSFLQIEAKDVDLGANVSYRIRSPEVKHLFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGMPASRVRYRVDDVQFPYPASIFDVEEDSGRVVTRVNLNEEPTTIFKLVVVAFDDGEPVMSSSATVRILVLHPGEIPRFTQEEYRPPPVSELAARGTVVGVISAAAINQSIVYSIVAGNEEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENDHPPVFQKKFYIGGVSEDARMFASVLRVKATDRDTGNYSAMAYRLIIPPIKEGKEGFVVETYTGLIKTAMLFHNMRRSYFKFQVIATDDYGKGLSGKADVLVSVVNQLDMQVIVSNVPPTLVEKKIEDLTEILDRYVQEQIPGAKVVVESIGARRHGDAYSLEDYSKCDLTVYAIDPQTNRAIDRNELFKFLDGKLLDINKDFQPYYGEGGRILEIRTPEAVTSIKKRGESLGYTEGALLALAFIIILCCIPAILVVLVSYRQFKVRQAECTKTARIQSAMPAAKPAAPVPAAPAPPPPPPPPPPGAHLYEELGESAMHNLFLLYHFEQSRGNNSVPEDRSSHRDGMAFSSSTTESHEPAHVEGPLKESQPNPARTFSFVPDEDNLSTHNPLYMESIGQRSTNSDLQPRTDFEELLAPRTQVKSQSLRGPREKIQRVWNQSVSFPRRLMWKAPNRPETIDLVEWQITNQRAECESARCHPSQRGSSNVLLATEDAHESEKEGGHRDTLIVQQTEQLKSLSSGSSFSSSWSHFSFSTLPTISRAVELGSEPNVVTSPADCTLELSPPLRPRILNSLSSKRETPTCASDTEPKRNSFEIAPHPPSISAPLPHPPLPRPPIAFTTFPLPLSPPNPPPPQLVTFSLPISTPPTSSLPLPPPLSLPPPPRPPAPRLFPQPPSTSIPSTDSISAPAAKCTASATHARETTSTTQPPASNPQWGAEPHRHPKGILRHVKNLAELEKSVSNMYSHIEKNCPPADPSKLHTFCPAEKTGMKITHDQSQETLVRVVEGIDVQPHSQSTSL", "output": "Calcium-dependent cell-adhesion protein. Required for inner ear neuroepithelial cell elaboration and cochlear function. Probably involved in the maintenance of normal retinal function."}]}
+{"id": "function_test_250", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAREHAIGEATGKRKKRGRVEEAEEYCNDGIEEQVEDEKLPLEVGMFYYPMTPPSFIVSDALEPDFPLIYVNRVFEVFTGYRADEVLGRNCRFLQYRDPRAQRRHPLVDPVVVSEIRRCLEEGIEFQGELLNFRKDGTPLVNRLRLAPIRDDDGTITHVIGIQVFSETTIDLDRVSYPVFKHKQQLDQTSECLFPSGSPRFKEHHEDFCGILQLSDEVLAHNILSRLTPRDVASIGSACRRLRQLTKNESVRKMVCQNAWGKEITGTLEIMTKKLRWGRLARELTTLEAVCWRKFTVGGIVQPSRCNFSACAVGNRLVLFGGEGVNMQPLDDTFVLNLDAECPEWQRVRVTSSPPGRWGHTLSCLNGSWLVVFGGCGRQGLLNDVFVLDLDAKHPTWKEVAGGTPPLPRSWHSSCTIEGSKLVVSGGCTDAGVLLSDTFLLDLTTDKPTWKEIPTSWAPPSRLGHSLSVFGRTKILMFGGLANSGHLKLRSGEAYTIDLEDEEPRWRELECSAFPGVVVPPPRLDHVAVSMPCGRVIIFGGSIAGLHSPSQLFLIDPAEEKPSWRILNVPGKPPKLAWGHSTCVVGGTRVLVLGGHTGEEWILNELHELCLASRQDSDL", "output": "Component of an E3 ubiquitin ligase complex that plays a central role in blue light-dependent circadian cycles. Acts as a blue light photoreceptor, due to the presence of FMN, that mediates light-regulated protein degradation of critical clock components by targeting them to the proteasome complex. The SCF(ADO3) E3 ubiquitin ligase complex is involved in the regulation of circadian clock-dependent processes including transition to flowering time, hypocotyl elongation, cotyledons and leaf movement rhythms. Forms a complex with 'GIGANTEA' (GI) to regulate 'CONSTANS' (CO) expression. Promotes CO expression during the light period of long days by decreasing the stability of CDF1 and CDF2 and by interacting directly with the CO protein and stabilizing it. ADO3 function is mainly GI dependent. Does not act as a regulator of CDF1 transcription. The interactions of ADO1/ZTL and ADO2 with ADO3 prevent its interaction with CDF1."}]}
+{"id": "function_test_251", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPVSGMERERKVSMRLHRGAPVNVSSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR", "output": "Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Phosphorylates connexin-43/GJA1, MAP1A, SNAPIN, MAPT/TAU, TOP2A, DCK, HIF1A, EIF6, p53/TP53, DVL2, DVL3, ESR1, AIB1/NCOA3, DNMT1, PKD2, YAP1, PER1 and PER2. Central component of the circadian clock. In balance with PP1, determines the circadian period length through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. Controls PER1 and PER2 nuclear transport and degradation. YAP1 phosphorylation promotes its SCF(beta-TRCP) E3 ubiquitin ligase-mediated ubiquitination and subsequent degradation. DNMT1 phosphorylation reduces its DNA-binding activity. Phosphorylation of ESR1 and AIB1/NCOA3 stimulates their activity and coactivation. Phosphorylation of DVL2 and DVL3 regulates WNT3A signaling pathway that controls neurite outgrowth. Phosphorylates NEDD9/HEF1 . EIF6 phosphorylation promotes its nuclear export. Triggers down-regulation of dopamine receptors in the forebrain. Activates DCK in vitro by phosphorylation. TOP2A phosphorylation favors DNA cleavable complex formation. May regulate the formation of the mitotic spindle apparatus in extravillous trophoblast. Modulates connexin-43/GJA1 gap junction assembly by phosphorylation. Probably involved in lymphocyte physiology. Regulates fast synaptic transmission mediated by glutamate."}]}
+{"id": "function_test_252", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MARTHFIFLLLVALLSTTFPSSSSSREQEKDRIKALPGQPKVAFSQYSGYVNVNQSHGRALFYWLTESSSPSPHTKPLLLWLNGGPGCSSIAYGASEEIGPFRINKTGSNLYLNKFAWNKDANLLFLESPAGVGYSYTNTSSDLKDSGDERTAQDNLIFLIKWLSRFPQYKYRDFYIAGESYAGHYVPQLAKKINDYNKAFSKPIINLKGFLVGNAVTDNQYDSIGTVTYWWTHAIISDKSYKSILKYCNFTVERVSDDCDNAVNYAMNHEFGDIDQYSIYTPTCVAAQQKKNTTGFFVRMKNTLLRRRLVSGYDPCTESYAEKYFNRPDVQRAMHANVTGIRYKWTACSDVLIKTWKDSDKTMLPIYKELAASGLRIWIFSGDTDSVVPVTATRFSLSHLNLPVKTRWYPWYTDNQVGGWTEVYKGLTFATVRGAGHEVPLFEPKRALILFRSFLAGKELPRSY", "output": "Active serine carboxypeptidase with broad substrate preference, including basic and hydrophilic groups. Processes a protein involved in an early event in the brassinosteroid signaling pathway."}]}
+{"id": "function_test_253", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAIRARSSSYAAAAVALALALASVAAVAGEVFFQEKFEDGWESRWVKSEWKKDENMAGEWNHTSGKWNGDPEDKGIQTSEDYRFYAISAEYPEFSNKDKTLVLQFSVKHEQKLDCGGGYVKLLGGDVDQKKFGGDTPYSIMFGPDICGYSTKKVHTIFTKNDKNHLIKKDVPCETDQLSHVYTLIIHPDATYTILIDNVEKQSGSIYEHWDILPPKQIKDPEAKKPEDWDDKEYIPDPEDKKPEGYDDIPKEIPDPDAKKPEDWDDEEDGEWTAPTIPNPEYKGPWKQKKIKNPNYQGKWKAPMIDNPDFKDDPYIYAFDSLKYIGIELWQVKSGTLFDNFLITDDPELAKTFAEETWGKHKDAEKAAFDEAEKKKEEEEAAKAGEDDDDLDDEDAEDEDKADEKADSDAEDGKDSDDEKHDEL", "output": "Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle. This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity)."}]}
+{"id": "function_test_254", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAPLLGRKPFPLVKPLPGEEPLFTIPHTQEAFRTREEYEARLERYSERIWTCKSTGSSQLTHKEAWEEEQEVAELLKEEFPNWYEKLVLEMVHHNTASLEKLVDSAWLEIMTKYAVGEECDFEVGKEKMLKVKIVKIHPLEKVDEEAVEKKSDGACDSPSSDKENSSQMAQDLQKKETVVKEDEGRRESINDRARRSPRKLPTSLKKGERKWAPPKFLPHKYDVKLQNEDKIISNVPADSLIRTERPPNKEILRYFIRHNALRAGTGENAPWVVEDELVKKYSLPSKFSDFLLDPYKYMTLNPSTKRRNTGSPDRKPSKKPKRDSSSLSSPLNPKLWCHVHLEKSLNGPPLKVKNSKNSKSPEEHLEGVMKIMSPNNNKLHSFHIPKKGPAAKKPGKHSDKPLKAKGRGKGILNGQKSTGNSKSPSKCVKTPKTKMKQMTLLDMAKGTQKMTRTPRSSGGVPRSSGKPHKHLPPAALHLIAYYKENKDKEDKKSALSCVISKTARLLSNEDRARLPEELRALVQKRYELLEHKKRWASMSEEQRKEYLKKKRQELKERLREKAKERREREMLERLEKQKRFEDQELGGRNLPAFRLVDTPEGLPNTLFGDVALVVEFLSCYSGLLLPDAQYPITAVSLMEALSADKGGFLYLNRVLVILLQTLLQDEIAEDYGELGMKLSEIPLTLHSVSELVRLCLRRCDVQEDSEGSETDDNKDSTPFEDNEVQDEFLEKLETSEFFELTSEEKLRILTALCHRILMTYSVQDHMETRQQVSAELWKERLAVLKEENDKKRAEKQKRKEMEARNKENGKEENVLGKVDRKKEIVKIEQQVEVEADDMISAVKSRRLLSMQAKRKREIQERETKVRLEREAEEERMRKHKAAAEKAFQEGIAKAKLVLRRTPIGTDRNHNRYWLFSNEVPGLFIEKGWVHNSIDYRFKHHRKDHSNLPDDDYCPRSKKANLGKNASVNAHHGPALEAVETTVPKQGQNLWFLCDSQKELDELLSCLHPQGIRESQLKERLEKRYQEITHSIYLARKPNLGLKSCDGNQELLNFLRSDLIEVATRLQKGGLGYMEGTSEFEARVISLEKLKDFGECVIALQASVIKKFLQGFMAPKQKKRKLQSEDSTKSEEVDEEKKMVEEAKVASALEKWKTAIREAQTFSRMHVLLGMLDACIKWDMSAENARCKVCRKKGEDDKLILCDECNKAFHLFCLRPALYEVPDGEWQCPACQPPTARRNSRGRNYTEESTSEGSEGDESGEEEEEEEEEEEEEEDYEVAGLRLRPRKTIRGKQSVIPAARPGRPPGKKSHPARRSRPKDDPEVDDLVLQTKRISRRQSLELQKCEDILHKLVKYRFSWPFREPVTRDEAEDYYDVIEHPMDFQTIQNKCSCGNYRSVQEFLTDMKQVFANAELYNCRGSHVLSCMEKTEQCLLALLQKHLPGHPYVRRKRRKFPDRLADDEGDSDSESVGQSRGRRQKK", "output": "Atypical tyrosine-protein kinase that plays a central role in chromatin remodeling and acts as a transcription regulator (By similarity). Involved in DNA damage response by phosphorylating 'Tyr-142' of histone H2AX (H2AXY142ph) . H2AXY142ph plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress . Regulatory subunit of the ATP-dependent WICH-1 and WICH-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair . Both complexes regulate the spacing of nucleosomes along the chromatin and have the ability to slide mononucleosomes to the center of a DNA template . The WICH-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the WICH-5 ISWI chromatin remodeling complex (By similarity). The WICH-5 ISWI chromatin remodeling complex regulates the transcription of various genes, has a role in RNA polymerase I transcription . Within the B-WICH complex has a role in RNA polymerase III transcription (By similarity). Mediates the recruitment of the WICH-5 ISWI chromatin remodeling complex to replication foci during DNA replication (By similarity)."}]}
+{"id": "function_test_255", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MANVTLKPLCPLLEEMVQLPNHSNSSLRYIDHVSVLLHGLASLLGLVENGLILFVVGCRMRQTVVTTWVLHLALSDLLAAASLPFFTYFLAVGHSWELGTTFCKLHSSVFFLNMFASGFLLSAISLDRCLQVVRPVWAQNHRTVAVAHRVCLMLWALAVLNTIPYFVFRDTIPRLDGRIMCYYNLLLWNPGPDRDTTCDYRQKALAVSKFLLAFMVPLAIIASSHVAVSLRLHHRGRQRTGRFVRLVAAIVVAFVLCWGPYHIFSLLEARAHSVTTLRQLASRGLPFVTSLAFFNSVVNPLLYVFTCPDMLYKLRRSLRAVLESVLVEDSDQSGGLRNRRRRASSTATPASTLLLADRIPQLRPTRLIGWMRRGSAEVPQRV", "output": "Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses (By similarity)."}]}
+{"id": "function_test_256", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MANEVILLDFWPSMFGMRTRIALREKGVEFEYREEDLRNKSPLLLQMNPIHKKIPVLIHNGKPVNESIIQVQYIDEVWSHKNPILPSDPYLRAQARFWADFIDKKLYDAQRKVWATKGEEQEAGKKDFIEILKTLESELGDKPYFSGDDFGYVDIALIGFYTWFPAYEKFANFSIESEVPKLIAWVKKCLQRESVAKSLPDPEKVTEFVSELRKKFVPE", "output": "Catalyzes the glutathionylation of 12-oxophytodienoate (OPDA). In vitro, possesses glutathione S-transferase activity toward 1-chloro-2,4-dinitrobenzene (CDNB) and benzyl isothiocyanate (BITC), and glutathione peroxidase activity toward cumene hydroperoxide."}]}
+{"id": "function_test_257", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRGRLCVGRAAAVAAAVAAAAVAVPLAGGQEGSQGGVRRGSRGTTMVKKRKGRVVIDSDTEDSGSDENLDQELLSLAKRKRSDSEEKEPPVSQPAASSDSETSDSDDEWTFGSNKNKKKGKTRKVEKKGAMKKQANKAASSGSSDRDSSAESSAPEEGEVSDSESSSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEDDDKSSEKSDRSSRTSSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRHKLERWCHMPFFAKTVTGCFVRIGIGNHNSKPVYRVAEITGVVETAKVYQLGGTRTNKGLQLRHGNDQRVFRLEFVSNQEFTESEFMKWKEAMFSAGMQLPTLDEINKKELSIKEALNYKFNDQDIEEIVKEKERFRKAPPNYAMKKTQLLKEKAMAEDLGDQDKAKQIQDQLNELEERAEALDRQRTKNISAISYINQRNREWNIVESEKALVAESHNMRNQQMDPFTRRQCKPTIVSNSRDPAVQAAILAQLNAKYGSGVLPDAPKEMSKGQGKDKDLNSKTASDLSEDLFKVHDFDVKIDLQVPSSESKALAITSKAPPAKDGAPRRSLNLEDYKKRRGLI", "output": "Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser-5'-phosphorylated forms and is involved in transcriptional elongation, acting both independently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription of Hox and Wnt target genes. PAF1C is involved in hematopoiesis and stimulates transcriptional activity of KMT2A/MLL1. PAF1C is involved in histone modifications such as ubiquitination of histone H2B and methylation on histone H3 'Lys-4' (H3K4me3). PAF1C recruits the RNF20/40 E3 ubiquitin-protein ligase complex and the E2 enzyme UBE2A or UBE2B to chromatin which mediate monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1); UB2A/B-mediated H2B ubiquitination is proposed to be coupled to transcription. PAF1C is involved in mRNA 3' end formation probably through association with cleavage and poly(A) factors. Binds single-stranded DNA (By similarity). Required for maximal induction of heat-shock genes. Required for the trimethylation of histone H3 'Lys-4' (H3K4me3) on genes involved in stem cell pluripotency; this function is synergistic with CXXC1 indicative for an involvement of a SET1 complex."}]}
+{"id": "function_test_258", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGVALTRLAQWTAAGYETGTLEITPLNESILNEITKFVESFSYKYPQEAKFVFVEPLEWKTYLEPSAFELGYVVSATTAESEETGKDGQPLLFLSVPYIKVRSFGQLSQLLSIATDSKLQEAQACIEANRDPVVKILGPDYNEMKEDPTRLTLLDTIIKDKETYMKRKVAILLKQLDLHLLNHSLKYISLEISLNPGTFKKDIELLKRFSGKGEQTVLESIEYTSDYEFSNGCRAPPWRQIQGEICYVLVKPHDMETLCLTCSTEGVFLNGGKTEEEGEINYERKGEIYKDLVTCLKDKSPVFSENMSKHEIRFTEEQQKDNQIFEKPKTEDGHSSVAGSEKSKIEKISFGKSPMTKRLEPSLNWRVTVDYKDHKSSIKDSQEEKQGKLEKSSSVSVAPSRAQSHRKGGEKVEETVSESSSESEEDEEPPDHRQEANADLPSEYWQIQKLVKYLKGGNQTATVIALCSMRDFNLAQETCQLAIRDVGGLEVLINLLDTDEVKCKIGSLKILKEISHNPQIRRNIVDLGGLPIMVNILDSPHKSLKCLSAETIANVAKFKRARRAVRQHGGITKLVALLDCGQNSTEPTQPSLYETRDVEVARCGALALWSCSKSHSNKEAIRKAGGIPLLARLLKTSHENMLIPVVGTLQECASEENYRAAIKAERIIENLVKNLNSENEQLQEHCAMAIYQCAEDEETRDLVRLHGGLKPLASLLNNTDNKERLAAVTGAIWKCSISKENVIKFREYKAIETLVGLLTDQPEEVLVNVVGALGECCQEYENRVLVRKCGGIQPLVNLLVGINQALLVNVTKAVGACAVEPESMAIIDRLDGVRLLWSLLKNPHPDVKASAAWALCPCIENAKDAGEMVRSFVGGLELVVNLLKSDNKEVLASVCAAITNIAKDQENLAVITDHGVVPLLSKLANTNNDKLRRHLAEAISRCCMWGRNRVAFGEHKAVAPLVRYLKSNDTNVHRATAQALYQLSEDADNCITMHENGAVKLLLDMVGSPDQDLQEAAAGCISNIRRLALATEKARYN", "output": "Component of the outer dynein arm-docking complex (ODA-DC) that mediates outer dynein arms (ODA) binding onto the doublet microtubule (By similarity). Involved in mediating assembly of both ODAs and their axonemal docking complex onto ciliary microtubules ."}]}
+{"id": "function_test_259", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSGVSEEDPEGLGPQGLPALGGACLVTVDKKLNVLTEKVDRLLHFQEDVTEKLQCVCQGMDHLEQGLHRLEASQELGLAGPGSTSPAAAQAAWPEVLELVRAVRQEGAQHGARLEALFKMVVAVDRAITLVGSTIQNSKVDDFILQGTVPWRKGSLADGPEENKEQAEVAGVKPKHVLNTGSVQAATSRALWEESQKQDTPVGTVEGLPLIIDTSLKGADLTQAGASLRQGVEALDPGQEPPPTEAESRLPALASEDTGTTLELSVAIDRISEVLTSLRMSQSAGEGTSSSKPDCSEPGPQPLGPLTTDSDIHSDEGLPRISVRMREMTTPEELFETQGGSPIGSAEAPGPGTVLEDQIPKGARPFPPLPKRSCNNGGASAEEATGPGAEPIRGPSLVTRDWRDEPVGTTDLQQGRDPGAVSPEPGKDHAAQGPGRTEAGRRVSSAAEAAIVVLDDSAAPPAPFEHRVVSIKDTLISTSYTVSQHEVLGGGRFGQVHRCTERSTGLALAAKIIKVKNIKDREDVKNEINIMNQLSHVNLIQLYDAFESKNSFTLIMEYVDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVSQTGHQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADTFKGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWLNHLIAKASGSNVRLRSQLLLQKYMAQRKWKKHFHVVTAVNRLRKFPTCP", "output": "Calmodulin-dependent kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes. Increases cardiomyocyte contractility."}]}
+{"id": "function_test_260", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKIFRCCFKYTLQQKLFILLLTLWLFSLLKLLNVGRLLFPQRDIYLVEYSLSTSPFVRNRFPESGDAARDNVNCSGVYEHEPLEIGKSLEIRRRSIIDLEDGDVVAMTSDCDVYQTLRQYHEKLVSREEEDFPIAYSLVVHKDAIMVERLIRAIYNQHNLYCIHYDLKSPDTFKAAMNNLAKCFPNIFIASKLETVEYAHISRLQADWNCLSDLLKSSVQWKYVINLCGQDFPLKSNFELVTELKSLQGRNMLETVRPPSAKTERFTYHHELRQVPYDYMKLPVKTNVSKGAPPHNIQVFVGSAYFVLSRAFVKYIFNSSLVEDFFAWSKDTYSPDEHFWATLIRIPGIPGGISSSSQDVSDLQSKTRLVKWFYYEGFLYPNCTGSHLRSVCIYGAAELRWLLNEGHWFANKFDSKVDPILMKCLAEKLEEQQRKLIALSSEKFMTEGTRQSHTL", "output": "Glycosyltransferase that mediates core 2 O-glycan branching, an important step in mucin-type biosynthesis. Does not have core 4 O-glycan or I-branching enzyme activity."}]}
+{"id": "function_test_261", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSVALQELGGGGNMVEYKRATLRDEDAPETPVEGGASPDAVEAGFRKRTSRLLGLHTQLELVLAGVSLLLAALLLGCLVALGVQYHRDPSHSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAERKTQRFYLSCLQVERIEELGAQPLRDLIDKIGGWNVTGPWDQDNFMEVLKAVAGTYRATPFFTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTANEKVLTAYLDYMEELGMLLGGQPTSTREQMRQVLELEIQLANITVPQDQRRDEEKIYHKMSIAELQALAPSMDWLEFLSFLLSPLELGDSEPVVVYGTDYLQQVSELINRTEPSVLNNYLIWNLVQKTTSSLDHRFESAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRAAFEEALGHLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYTCNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACIEEQYSQYQVNGEKLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNSGQLCEVW", "output": "Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides (By similarity). May play a role in amyloid-beta processing (By similarity)."}]}
+{"id": "function_test_262", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDLLKTPSSTVGLSETFARLKSQGKVALIPYITAGDPDLSTTAKALKVLDSCGSDIIELGVPYSDPLADGPAIQAAARRSLLKGTNFNSIISMLKEVIPQLSCPIALFTYYNPILRRGVENYMTVIKNAGVHGLLVPDVPLEETETLRNEARKHQIELVLLTTPTTPKERMNAIVEASEGFIYLVSSVGVTGTRESVNEKVQSLLQQIKEATSKPVAVGFGISKPEHVKQVAEWGADGVIVGSAMVKILGESESPEQGLKELEFFTKSLKSALVS", "output": "The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate (By similarity). Contributes to the tryptophan-independent indole biosynthesis, and possibly to auxin production."}]}
+{"id": "function_test_263", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPPKTSGKAAKKAGKAQKNITKTDKKKKRKRKESYAIYIYKVLKQVHPDTGISSKAMSIMNSFVNDIFERIAAEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "output": "Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling."}]}
+{"id": "function_test_264", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "METVVRRCPFLSRVPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRTVSTSAAQCQQVKETPPANEKEKTAKAAVQQAPDESQMAQTPDGTQLPPGHPSPSTSQSSGSKCPFLAAQLSQTGSSVFRKASLELQEDVQEMHAVRKEVAQSPVLPSLVNAKRDGEGPSPLLKNFQDIMRKQRPERVSHLLQDNLPKSVSTFQYDHFFEKKIDEKKNDHTYRVFKTVNRRAQIFPMADDYTDSLITKKQVSVWCSNDYLGMSRHPRVCGAVIETVKQHGAGAGGTRNISGTSKFHVELEQELADLHGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVNHLRELLQRSDPSVPKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYGASGGGIGDRDGVMPKMDIISGTLGKAFGCVGGYIASTSLLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSNEGRALRRQHQRNVKLMRQMLMDAGLPVIHCPSHIIPVRVADAAKNTEICDELMTRHNIYVQAINYPTVPRGEELLRIAPTPHHTPQMMNFFLEKLLLTWKRVGLELKPHSSAECNFCRRPLHFEVMSEREKAYFSGMSKMVSAQA", "output": "Catalyzes the pyridoxal 5'-phosphate (PLP)-dependent condensation of succinyl-CoA and glycine to form aminolevulinic acid (ALA), with CoA and CO2 as by-products."}]}
+{"id": "function_test_265", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTKVNIVIIDDHQLFREGVKRILDFEPTFEVVAEGDDGDEAARIVEHYHPDVVIMDINMPNVNGVEATKQLVELYPESKVIILSIHDDENYVTHALKTGARGYLLKEMDADTLIEAVKVVAEGGSYLHPKVTHNLVNEFRRLATSGVSAHPQHEVYPEIRRPLHILTRRECEVLQMLADGKSNRGIGESLFISEKTVKNHVSNILQKMNVNDRTQAVVVAIKNGWVEMR", "output": "Member of the two-component regulatory system DegS/DegU, which plays an important role in the transition growth phase. Involved in the control of expression of different cellular functions, including production of degradative enzymes such as the neutral and alkaline proteases, flagellum formation, biofilm formation, and competence for DNA uptake. Positively or negatively regulates expression of many different genes. The phosphorylated form is required for synthesis of degradative enzymes, flagellum formation and biofilm formation. The unphosphorylated form is required for expression of genetic competence, via induction of comK."}]}
+{"id": "function_test_266", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSSRKSTASSLLLRQYRELTDPKKAIPSFHIELEDDSNIFTWNIGVMVLNEDSIYHGGFFKAQMRFPEDFPFSPPQFRFTPAIYHPNVYRDGRLCISILHQSGDPMTDEPDAETWSPVQTVESVLISIVSLLEDPNINSPANVDAAVDYRKNPEQYKQRVKMEVERSKQDIPKGFIMPTSESAYISQSKLDEPESNKDMADNFWYDSDLDDDENGSVILQDDDYDDGNNHIPFEDDDVYNYNDNDDDDERIEFEDDDDDDDDSIDNDSVMDRKQPHKAEDESEDVEDVERVSKKI", "output": "Catalyzes the covalent attachment of ubiquitin to other proteins. Capable, in vitro, to ubiquitinate histone H2A.; "}]}
+{"id": "function_test_267", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MARPLSDRTPGPLLLGGPAGAPPGGGALLGLRSLLQGNSKPKEPASCLLKEKERKATLPSAPVPGPVLETAGPADAPTGAVSGGGSPRGRSGPVAGPSLFAPLLWERTLPFGDVEYVDLDAFLLEHGLPPSPPPPGGLSPAPSPARTPAPSPGPGSCSSSSPRSSPGHAPARATLGAAGGHRAGLTSRDTPSPVDPDTVEVLMTFEPDPADLALSSIPGHETFDPRRHRFSEEELKPQPIMKKARKVQVPEEQKDEKYWSRRYKNNEAAKRSRDARRLKENQISVRAAFLEKENALLRQEVVAVRQELSHYRAVLSRYQAQHGTL", "output": "This transcriptional activator recognizes and binds to the sequence 5'-RTTAYGTAAY-3' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation (By similarity)."}]}
+{"id": "function_test_268", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDLTLLWVLLPLVTVAWGQYGDYGYSYHQYHDYSDDGWVNLNRQGFSYQCPHGQVVVAVRSIFNKKEGSDRQWNYACMPTPQSLGEPTECWWEEINRAGMEWYQTCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWLTTEYPGHYGEEMDMISYNYDYYMRGATTTFSAVERDRQWKFIMCRMTDYDCEFANV", "output": "Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation."}]}
+{"id": "function_test_269", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKFLGGNDDRNGRGGVGVGTDAIVGSRGGVSQDAADAAGAAAAAAVGYVFQQRPSPGGVGVGVGGVGGGVPGVGAVGSTLHEAAAAEYAAHFAQKQQQTRWACGDDGHGIDNPDKWKYNPPMNPANAAPGGPPGNGSNGGPGAIGTIGMGSGLGGGGGGGAGGGNNGGSGTNGGLHHQSMAAAAANMAAMQQAAALAKHNHMISQAAAAVAAQQQHQHPHQQHPQQQQQQQQAQNQGHPHHLMGGGNGLGNGNGLGIQHPGQQQQQQQQQQQQQHPGQYNANLLNHAAALGHMSSYAQSGGSMYDHHGGAMHPGMNGGMPKQQPLGPPGAGGPQDYVYMGGQTTVPMGAAMMPPQNQYMNSSAVAAANRNAAITTSTAKKLWEKSDGKGVSSSTPGGPLHPLQIPGIGDPSSVWKDHTWSTQGENILVPPPSRAYAHGGASDTSNSGNAGILSPRDSTCAKVVEYVFSGSPTNKDSSLSGLEPHLRNLKFDDNDKSRDDKEKANSPFDTNGLKKDDQVTNSNGVVNGIDDDKGFNRTPGSRQPSPAEESQPRPPNLLFPPLPFNHMLMDHGQGMGGGLGGVVGSGNGVGGGSGGGGAGGAYAAHQQMAAQMSQLQPPMMNGVGGGMPMAAQSPMLNHQAAGPNHMESPGNLLQQQNFDVQQLFRSQNPGLAAVATNAAAAAAAAAAATSAASAAAAVGAPPVPNGSLQQSQQQQQQQQQQQQQQQMHMAAASQQFLAAQQQAQNAAYAAQQATSYVINPGQEAAPYMGMIAAAQMPYYGVAPWGMYPGNLIPQQGTQPRRPLTPSQQGAENQPYQVIPAFLDHTGSLLMGGPRTGTPMRLVSPAPVLVPPGATRAGPPPPQGPQLYQPQPQTAQQNLYSQQNGSSVGGLALNTSSLTGRRDSFDRSTSAFSPSTMDYTSSGVAAAANAVNSTVAQAAAAAAAAAAARGKWPGAMSGAASGAYGALGAGNASASPLGAPITPPPSAQSCLLGSRAPGAESRQRQQQQQQLAAVGLPATAAAAQAAVAAAANNMFGSNSSIFSNPLAIPGTAAVAAAAAAAAAANSRQVAATAAAAAAVAAAAGGVGGAPQPGRSRLLEDFRNQRYPNLQLRDLANHIVEFSQDQHGSRFIQQKLERATAAEKQMVFSEILAAAYSLMTDVFGNYVIQKFFEFGTPEQKNTLGMQVKGHVLQLALQMYGCRVIQKALESISPEQQQEIVHELDGHVLKCVKDQNGNHVVQKCIECVDPVALQFIINAFKGQVYSLSTHPYGCRVIQRILEHCTAEQTTPILDELHEHTEQLIQDQYGNYVIQHVLEHGKQEDKSILINSVRGKVLVLSQHKFASNVVEKCVTHATRGERTGLIDEVCTFNDNALHVMMKDQYANYVVQKMIDVSEPTQLKKLMTKIRPHMAALRKYTYGKHINAKLEKYYMKITNPITVGTGAGGVPAASSAAAVSSGATSASVTACTSGSSTTTTSTTNSLASPTICSVQENGSAMVVEPSSPDASESSSSVVSGAVNSSLGPIGPPTNGNVVL", "output": "Sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3'-UTR of mRNA targets. Binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5'-UGUANAUA-3', that is related to the Nanos Response Element (NRE) . Mediates post-transcriptional repression of transcripts via different mechanisms: acts via direct recruitment of deadenylase complexes leading to translational inhibition and mRNA degradation (By similarity). Also mediates deadenylation-independent repression by promoting accessibility of miRNAs . Mediates post-transcriptional silencing of E2f mRNA by binding to its 3'-UTR and promoting miRNA regulation . Required for abdominal development and to support proliferation and self-renewal of germ cells. Pum is the only gene required for nos activity that is not also required for posterior localization of germline determinants. Pum is required during embryogenesis when nos activity apparently moves anteriorly from the posterior pole ."}]}
+{"id": "function_test_270", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKSLCLLAIVAVVSAEVYFKEEFNDASWEKRWVQSKHKDDFGAFKLSAGKFFDVESRDQGIQTSQDAKFYSRAAKFDKDFSNKGKTLVIQYTVKHEQGIDCGGGYVKVMRADADLGDFHGETPYNVMFGPDICGPTRRVHVILNYKGENKLIKKEITCKSDELTHLYTLILNSDNTYEVKIDGESAQTGSLEEDWDLLPAKKIKDPDAKKPEDWDEREYIDDAEDAKPEDWEKPEHIPDPDAKKPEDWDDEMDGEWEPPMIDNPEYKGEWKPKQIKNPAYKGKWIHPEIENPEYTPDDELYSYESWGAIGFDLWQVKSGTIFDNIIITDSVEEAEAHAAETFDKLKTVEKEKKEKADEETRKAEEEARKKAEEEKEAKKDDDEEEKEEEEGHDEL", "output": "Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle (By similarity). This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity). Probably by controlling the folding of extracellular matrix protein unc-52/Perlecan, may play a role in the formation of fibrous organelles, a hemidesmosome-like structure attaching muscles to the epidermis . Protects dopaminergic neurons against oxidative stress-induced neurodegeneration . May play a role in protection against ER stress . Plays a role in modulating lifespan, acting by influencing ER calcium homeostasis ."}]}
+{"id": "function_test_271", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGGSSRRQRSTSATRRDDKRRRRQCFSSVADDEEETTSIYGVSSIFIWILATSSLILVISSPSSNTSIQSSSYDRITTKHLLDNISPTFKMYTDSNNRNFDEVNHQHQQEQDFNGQSKYDYPQFNRPMGLRWRDDQRMMEYFMSNGPVETVPVMPILTEHPPASPFGRGPSTERPTTSSRYEYSSPSLEDIDLIDVLWRSDIAGEKGTRQVAPADQYECDLQTLTEKSTVAPLTAEENARYEDLSKGFYNGFFESFNNNQYQQKHQQQQREQIKTPTLEHPTQKAELEDDLFDEDLAQLFEDVSREEGQLNQLFDNKQQHPVINNVSLSEGIVYNQANLTEMQEMRDSCNQVSISTIPTTSTAQPETLFNVTDSQTVEQWLPTEVVPNDVFPTSNYAYIGMQNDSLQAVVSNGQIDYDHSYQSTGQTPLSPLIIGSSGRQQQTQTSPGSVTVTATATQSLFDPYHSQRHSFSDCTTDSSSTCSRLSSESPRYTSESSTGTHESRFYGKLAPSSGSRYQRSSSPRSSQSSIKIARVVPLASGQRKRGRQSKDEQLASDNELPVSAFQISEMSLSELQQVLKNESLSEYQRQLIRKIRRRGKNKVAARTCRQRRTDRHDKMSHYI", "output": "Transcription factor . Required to specify the fate of ventral blastomeres in the early embryo, and postembryonically for the development of the intestine . Directly regulates expression of zygotically expressed med-1 and med-2 to direct mesendoderm development . In response to oxidative stress and anoxia, required to up-regulate expression of stl-1 mRNA . Involved in regulating innate immunity, acting downstream of the pmk-1 p38/MAPK pathway and probably also downstream of nipi-3 . Required for the up-regulation of phase II detoxification genes, including gcs-1 and several glutathione-S-transferase mRNAs in response to oxidative stress generated during pathogenic bacterial infection . Modulates oxidative stress responses in concert with transcription factors such as hcf-1 and elt-3 . Regulates the transcription of genes associated with metabolism in response to changes in nutrient availability . In neurons, involved in mitochondrial fusion and behavioral recovery during reoxygenation . Required for riok-1 mRNA expression in the intestine . Downstream of the let-60/Ras, mek-2 and pmk-1 pathway, positively regulates lifespan probably by preventing transcription of insulin-like peptides such as ins-39 . Prevents degeneration of dopaminergic CEP neurons in response to high Al(3+) or Mn(2+) levels, probably by promoting the expression of glutathione-S-transferase gst-1 .; "}]}
+{"id": "function_test_272", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQRAWILLTLGLMACVSAETRAELTSDKDMYLDSSSIEEASGLYPIDDDDYSSASGSGAYEDKGSPDLTTSQLIPRISLTSAAPEVETMTLKTQSITPTQTESPEETDKKEFEISEAEEKQDPAVKSTDVYTEKHSDNLFKRTEVLAAVIAGGVIGFLFAIFLILLLVYRMRKKDEGSYDLGERKPSSAAYQKAPTKEFYA", "output": "Cell surface proteoglycan which regulates dendritic arbor morphogenesis."}]}
+{"id": "function_test_273", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRNLTKTSLLLAGLCTAAQMVFVTHASAEESIEYDHTYQTPSYIIEKSPQKPVQNTTQKESLFSYLDKHQTQFKLKGNANSHFRVSKTIKDPKTKQTFFKLTEVYKGIPIYGFEQAVAMKENKQVKSFFGKVHPQIKDVSVTPSISEKKAIHTARRELEASIGKIEYLDGEPKGELYIYPHDGEYDLAYLVRLSTSEPEPGYWHYFIDAKNGKVIESFNAIHEAAGTGIGVSGDEKSFDVTEQNGRFYLADETRGKGINTFDAKNLNETLFTLLSQLIGYTGKEIVSGTSVFNEPAAVDAHANAQAVYDYYSKTFGRDSFDQNGARITSTVHVGKQWNNAAWNGVQMVYGDGDGSKFKPLSGSLDIVAHEITHAVTQYSAGLLYQGEPGALNESISDIMGAMADRDDWEIGEDVYTPGIAGDSLRSLEDPSKQGNPDHYSNRYTGTEDYGGVHINSSIHNKAAYLLAEGGVHHGVQVEGIGREASEQIYYRALTYYVTASTDFSMMKQAAIEAANDLYGEGSKQSASVEKAYEAVGIL", "output": "Protease able to cleave casein in vitro."}]}
+{"id": "function_test_274", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEEFNSSGSVVNGTGSTEVPQSNAEVIRGQIFEVGPRYIKLAYIGEGAYGMVVSADDTLTNQRVAIKKISPFEHQTYCQRTLREITILTRFKHENIIDIRDILRVDSIDQMRDVYIVQCLMETDLYKLLKTQRLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNKTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSRDDLECIINEKARNYLESLPFKPNVPWAKLFPNADALALDLLGKMLTFNPHKRIPVEEALAHPYLEQYYDPGDEPVAEVPFRINMENDDISRDALKSLIFEETLKFKERQPDNAP", "output": "Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway to regulate proliferation, differentiation and effect cell fate decisions in various tissues . Required downstream of phl/Raf in the sev/sevenless, tor/torso, and EGF receptor homolog Egfr signal transduction pathways . Required for embryonic epithelial tissue repair . During larval development, mediates Ptth/tor signaling leading to the production of ecdysone, a hormone required for the initiation of metamorphosis ."}]}
+{"id": "function_test_275", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAEIRKLKNYINGEWVESKTDQYEDVVNPATKEVLCQVPISTKEDIDYAAQTAAEAFKTWSKVAVPRRARILFNFQQLLSQHKEELAHLITIENGKNTKEALGEVGRGIENVEFAAGAPSLMMGDSLASIATDVEAANYRYPIGVVGGIAPFNFPMMVPCWMFPMAIALGNTFILKPSERTPLLTEKLVELFEKAGLPKGVFNVVYGAHDVVNGILEHPEIKAISFVGSKPVGEYVYKKGSENLKRVQSLTGAKNHTIVLNDANLEDTVTNIVGAAFGSAGERCMACAVVTVEEGIADEFMAKLQEKVADIKIGNGLDDGVFLGPVIREDNKKRTLSYIEKGLEEGARLVCDGRENVSDDGYFVGPTIFDNVTTEMTIWKDEIFAPVLSVIRVKNLKEAIEIANKSEFANGACLFTSNSNAIRYFRENIDAGMLGINLGVPAPMAFFPFSGWKSSFFGTLHANGKDSVDFYTRKKVVTARYPAPDFN", "output": "Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively."}]}
+{"id": "function_test_276", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTQEFIDKVSSYLTPDVDIAPISQGAEAIVFTTTTHPYLPRAKDSHQKYIIKYRPPKRYRHPQIDQALTKHRTLNESRLLAKLYLIPGLCVPQLIACDPYNGFIWLEFLGEDLPGGHGFSNLKNFLWMHDQDPYSDLVATTLRKVGRQIGLLHWNDYCHGDLTSSNIVLVRDGARWTPHLIDFGLGSVSNLVEDKGVDLYVLERAILSTHSKHAEKYNAWIMEGFEEVYREQGAKGAKKLKEVTKRFEEVRLRGRKRSMLG", "output": "Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. BUD32 has ATPase activity in the context of the EKC/KEOPS complex and likely plays a supporting role to the catalytic subunit KAE1. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. Important for bud site selection."}]}
+{"id": "function_test_277", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSFLPSFILSDESKERISKILTLTHNVAHYGWIPFVLYLGWAHTSNRPNFLNLLSPLPSV", "output": "Component of the TOM (translocase of outer membrane) receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. TOM7 is involved in assembly and stability of the TOM complex."}]}
+{"id": "function_test_278", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAPKKSTTKTTSKGKKPATSKGKEKSTSKAAIKKTTAKKEEASSKSYRELIIEGLTALKERKGSSRPALKKFIKENYPIVGSASNFDLYFNNAIKKGVEAGDFEQPKGPAGAVKLAKKKSPEVKKEKEVSPKPKQAATSVSATASKAKAASTKLAPKKVVKKKSPTVTAKKASSPSSLTYKEMILKSMPQLNDGKGSSRIVLKKYVKDTFSSKLKTSSNFDYLFNSAIKKCVENGELVQPKGPSGIIKLNKKKVKLST", "output": "Could act as an H1-type linker histone. Has been shown to bind DNA."}]}
+{"id": "function_test_279", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTEEDRKLTVETETVEAPVANNLLLSNNSNVVAPNPSIPSASTSTSPLHREIVDDSVATANTTSNVVQHNLPTIDNNLMDSDATSHNQDHWHSDINRAGTSMSTSDIPTDLHLEHIGSVSSTNNNSNNALINHNPLSSHLSNPSSSLRNKKSSLLVASNPAFASDVELSKKKPAVISNNMPTSNIALYQTARSANIHGPSSTSASKAFRKASAFSNNTAPSTSNNIGSNTPPAPLLPLPSLSQQNKPKIIERPTMHVTNSREILLGENLLDDTKAKNAPANSTTHDNGPVANDGLRIPNHSNADDNENNNKMKKNKNINSGKNERNDDTSKICTTSTKTAPSTAPLGSTDNTQALTASVSSSNADNHNNNKKKTSSNNNGNNSNSASNKTNADIKNSNADLSASTSNNNAINDDSHESNSEKPTKADFFAARLATAVGENEISDSEETFVYESAANSTKNLIFPDSSSQQQQQQQQPPKQQQQQQNHGITSKISAPLLNNNKKLLSRLKNSRHISTGAILNNTIATISTNPNLNSNVMQNNNNLMSGHNHLDELSSIKQEPPHQLQQQQPPMDVQSVDSYTSDNPDSNVIAKSPDKRSSLVSLSKVSPHLLSSTSSNGNTISCPNVATNSQELEPNNDISTKKSLSNSTLRHSSANRNSNYGDNKRPLRTTVSKIFDSNPNGAPLRRYSGVPDHVNLEDYIEQPHNYPTMQNSVKKDEFYNSRNNKFPHGLNFYGDNNVIEEENNGDSSNVNRPQHTNLQHEFIPEDNESDENDIHSMFYYNHKNDLETKPLISDYGEDEDVDDYDRPNATFNSYYGSASNTHELPLHGRMPSRSNNDYYDFMVGNNTGNNNQLNEYTPLRMKRGQRHLSRTNNSIMNGSIHMNGNDDVTHSNINNNDIVGYSPHNFYSRKSPFVKVKNFLYLAFVISSLLMTGFILGFLLATNKELQDVDVVVMDNVISSSDELIFDITVSAFNPGFFSISVSQVDLDIFAKSSYLKCDSNGDCTVMEQERKILQITTNLSLVEESANNDISGGNIETVLLGTAKKLETPLKFQGGAFNRNYDVSVSSVKLLSPGSREAKHENDDDDDDDGDDGDDENNTNERQYKSKPNARDDKEDDTKKWKLLIKHDYELIVRGSMKYEVPFFNTQKSTAIQKDSMVHPGKK", "output": "The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Positively regulates FAB1 kinase activity. Major activator of FAB1 during hyperosmotic shock and can elevate levels of PtdIns(3,5)P2 in the absence of VAC14 and FIG4. Directly involved in vacuolar membrane scission. Required for normal vacuole acidification, inheritance and morphology."}]}
+{"id": "function_test_280", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MCDDEETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERFRCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDEAGPSIVHRKCF", "output": "Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells."}]}
+{"id": "function_test_281", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGINVDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQEETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG", "output": "Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism."}]}
+{"id": "function_test_282", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MATSPAEPSAGPAARGEAAAATEEQEEEARQLLQTLQAAEGEAAAAGAGDAAAAADSGSPSGPGSPRETVTEVPTGLRFSPEQVACVCEALLQAGHAGRLSRFLGALPPAERLRGSDPVLRARALVAFQRGEYAELYQLLESRPFPAAHHAFLQDLYLRARYHEAERARGRALGAVDKYRLRKKFPLPKTIWDGEETVYCFKERSRAALKACYRGNRYPTPDEKRRLATLTGLSLTQVSNWFKNRRQRDRTGTGGGAPCKSESDGNPTTEDESSRSPEDLERGVASMAAEAPAQSSIFLAGATSPATCPASSSILVNGSFLAASSPPAVLLNGSPVIINSLALGENSSLGPLLLTGGSAPQPQPSLQGVSEAKNSLVLDPQTGEVRLDEAQSEAPETKGVHGTTGEEIPGALPQVVPGPPPASTFPLTPGAVPAVAAPQVVPLSPSSGYPTGLSPTSPRLNLPQVVPTSQVVTLPQAVGPLQLLAAGPGSPVKVAAAAGPTNVHLINSSVGVTALQLPSSTAPGNFLLANPVSGSPIVTGVAVQQGKIILTATFPTSMLVSQVLPPAPSLALPLKQEPAITVPEGALPVGPSPTLPEGHTLGPISTQPLPPASVVTSGTSLPFSPDSSGLLSSFSAPLPEGLMLSPAAVPVWPAGLELSTGVEGLGTQATHTVLRLPDPDPQGLLLGATTGTEVDEGLEAEAKVLTQLQSVPVEEPLEL", "output": "Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5'-GGTGTCAG-3' motif present in the ARE regulatory element of ATP1A1. Binds a 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter (By similarity). Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3."}]}
+{"id": "function_test_283", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAPAGHILTLLLWGHLLELWTPGHSANPSYPRLRLSHKELLELNRTSIFQSPLGFLDLHTMLLDEYQERLFVGGRDLVYSLNLERVSDGYREIYWPSTAVKVEECIMKGKDANECANYIRVLHHYNRTHLLTCATGAFDPHCAFIRVGHHSEEPLFHLESHRSERGRGRCPFDPNSSFVSTLVGNELFAGLYSDYWGRDSAIFRSMGKLGHIRTEHDDERLLKEPKFVGSYMIPDNEDRDDNKMYFFFTEKALEAENNAHTIYTRVGRLCVNDMGGQRILVNKWSTFLKARLVCSVPGMNGIDTYFDELEDVFLLPTRDPKNPVIFGLFNTTSNIFRGHAVCVYHMSSIREAFNGPYAHKEGPEYHWSLYEGKVPYPRPGSCASKVNGGKYGTTKDYPDDAIRFARMHPLMYQPIKPVHKKPILVKTDGKYNLRQLAVDRVEAEDGQYDVLFIGTDTGIVLKVITIYNQETEWMEEVILEELQIFKDPAPIISMEISSKRQQLYIGSASAVAQVRFHHCDMYGSACADCCLARDPYCAWDGISCSRYYPTGAHAKRRFRRQDVRHGNAAQQCFGQQFVGDALDRTEERLAYGIESNSTLLECTPRSLQAKVIWFVQKGRDVRKEEVKTDDRVVKMDLGLLFLRVRKSDAGTYFCQTVEHNFVHTVRKITLEVVEEHKVEGMFHKDHEEERHHKMPCPPLSGMSQGTKPWYKEFLQLIGYSNFQRVEEYCEKVWCTDKKRKKLKMSPSKWKYANPQEKRLRSKAEHFRLPRHTLLS", "output": "Plays an important role in signaling via the cell surface receptor PLXND1. Mediates reorganization of the actin cytoskeleton, leading to the retraction of cell projections. Promotes focal adhesion disassembly and inhibits adhesion of endothelial cells to the extracellular matrix. Regulates angiogenesis, both during embryogenesis and after birth. Can down-regulate sprouting angiogenesis. Required for normal vascular patterning during embryogenesis. Plays an important role in ensuring the specificity of synapse formation."}]}
+{"id": "function_test_284", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MADTDEGFGLARTPLEPDSKDRSCDSKPESALGAPSKSPSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFRGSDDLELHRMSRMQSKEYPVVPRSTVRHKVTSNHSPFSSETRALSTSSNLGSQYQCENGVSGPSQDLLPPPNPYPLAQEHSQIYHCTKRKDEECSSTEHPYKKPYMETSPSEEDTFYRSGYPQQQGLSTSYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQCGPQTGLQSPGGLQPPEFLYTHGVPRTLSPHQYHSVHGVGMVPEWSENS", "output": "DNA-binding protein that regulates the transcription of several genes and is involved in heart development and limb pattern formation. Binds to the core DNA motif of NPPA promoter."}]}
+{"id": "function_test_285", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTTDISIVRWDPSQGPGNEYIDEYEYDGGNSSSRLFERSRIKALAEERESVQKKTFTKWVNSHLCRVNCRIADLYVDMRDGKHLIKLLEVLSGERLPKPTKGKMRIHCLENVDKALQFLREQRVHLENIGSHDIVDGNASLNLGLIWTIILRFQIQDITIEEVDNKETKSAKDALLLWCQMKTAGYHNVNVRNFTTSWRDGLAFNAIIHKHRPDLVQFEKLSKTNAIHNLNNAFDVAEDKLGLAKLLDAEDVFVEHPDEKSIITYVVTYYHYFSKLKQETVQGKRIGKVVGIAMENDKMVHDYENFTSDLLKWIETTIQSLGEREFENSLAGVQGQLAQFSNYRTIEKPPKFVEKGNLEVLLFTLQSKMRANNQKPYTPKEGKMISDINKAWERLEKAEHERELALREELIRQEKLEQLAARFDRKASMRETWLSENQRLVSQDNFGFDLAAVEAAAKKHEAIETDIFAYEERVQAVVAVCDELESERYHDVKRILLRKDNVMRLWTYLLELLRARRMRLEISLQLQQNFQEMLYILDNMEEIKQLLMTDDYGKHLMGVEDLLQKHSLVEADINILGERVKVVVQNSQKFLSDDPESYKPCDPEIIVSRVQQLEDAYAELVRLAVERRSRLEESRKLWQFYWDTADEENWIKEKEQIVSTDEVGHDLTTVNLMLSKHKALESEITSHDPQLQNVAKVGSELITEGHFGADRIKDRLKEILNKWDHLLDLTKYRRQRLENAVEYFQLFADADDVDNWMLDTLRIVSSEDVGRDEANVQSLLKKHKDVADELKNYAEVIDALHKQAESLKLNEAEKANVDKRLEAIDNRYKELTELAKLRKQRLLDALSLYKLMSEADGVEQWIKEKTKMLDTMTPGKDIEDVEIMKHRFEGFDKEMNANASRVAVVNQLARQLLHVEHPNSDEILERQNHLNQEWSTLREKAEAKMDDLKSAHGVQTFYIECRETISWIEDKKRILTETDSLEMDLTGVMTLQRRLSGMDRDLAAIQAKLSSLEREANSIEDEHPEEAKIIRERIAQIELIWEQLTQMLKERDSKLEEAGDLHRFLRDLDHFQTWLTKTQTDVASEDTPTSLPEAEKLLNQHQSIREEIDNYTEDYKNMMEYGERLTSEGSTSDDPQYMFLRERLNALKDGWEELHQMWENRQVLLSQSLDQQLFNRDARQTEVLLSQQEHFLSKDDTPVNLEQAENQLKRHEAFLTTMEANDDKINTLLQVADTLVEKDHFDADKIGKRAENITGRRDDNRQRALDQHEKLKNQVKLHEFLQDLEELAEWVQEKYATSQDESYRSAKTIHSKWTRHQAFEAEIAANKERLFEAEKSAQELSKEKPEFKDVIEPKLKELAKQFDDLEVHTKEKGAMLFDANREVLVQQTCDDIDSYITDLEKQIVSGDTANDLTSVNILMQKQQVIQTQMAVKARQVEEIDKQTEYLQKTVPEEKIEPIVVKKTAVLERFEKIKAPLLERQKALEKKKEAFQFCRDVEDEKLWIDEKLPVANSPDYGNSLFNVHVLKKKNQSLATEIDNHEPRINAICNNGRKLIDEGHEDAKKFEALISDLTQKWQELKDAIENRRKHLLESEKVQQYFFDAQEAESWMSEQELYMMVEDRGKDEISAQNLMKKHENLEQSVEDYANTIRQLGEVARQFSGDDISSGDAVAVKQSQLDKLYAGLKDLAGERRARLNEALQLFMLSREVDDLEQWITDREVVAGSQELGQDFDHVTLLSERFNEFARDTEAVGGERVAKVNGIADNLIQAGHSDSATIAEWKDNLNESWQDLLELIETRTQMLAASRELHKFFHDCKDVLGRILEKQHGVSDELGRDAGSVSTLQRKHYNFLQDLITLYSQVQQIQEESAKLQDAYAGDKAKEITNREQEVLHAWDNLQAMCDARKQKLADTGDLFRFFNMVRILMIWMEDLVRQMNTSEKPRDVSGVELLMNNHQSLKAEIDTREDNFGACISLGKELLTRNHYASADIKDRLMTLSNSRNALLRRWEERWENLQLILEVYQFARDAAVAEAWLIAQEPYLLSSELGHTIDEVENLIKKHEAFEKSAAAQEERFSALERLTTFELKEMKRRQELAEEAERQRIKEEQEAKAASEAAEQAKREAERRDDVDVGASHDDSERGGTPGAGEGHEGYVTRKHEWDSTTKKASNRSWDKVYMAAKAGRISFYKDQKGYKSNPELTFRGEPSYDLQNAAIEIASDYTKKKHVLRVKLANGALFLLQAHDDTEMSQWVTSLKAQSDSTAVAASRSQTLPATSQKDEPKRRSFFTLKKK", "output": "Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. Interacts with calmodulin in a calcium-dependent manner."}]}
+{"id": "function_test_286", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MADLEAVLADVSYLMAMEKSRSQPAARASKRIVLPDPSVRSIMQKFLEKSGDMKFDKIFNQKLGFLLLKDYAENVSESPCPQIKFYEAIKEYEKMETPDERLTKAREIYDHHIMVEMLAHAHNYSKESLQHVQYHLLKQNVPPDLFHRYVLEICDQLRGDIFQRFLESDKFTRFCQWKNLELNMQLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGQDCPFIVCMTYAFQSPDKLCFILDLMNGGDLHYHLSQHGVFTEQEMIFYASEVILGLEHMHNRFVVYRDLKPANILLDENGHVRVSDLGLACDYSKKKPHASVGTHGYMAPEVLAKGVAYDSSADWFSLGCMLYKLLKGHSPFRQHKSKDKNEIDKMTLTQDIELPNEGLSKDCRDLLEGLLKRDVPDRLGCRGKGPTEVKEHPFFKDVDWQTVYLRRMTPPLIPPRGEVNAADAFDIGNFDDDEVKGVKLQDGDSDLYKNFNIVISERWQNEIAETIFEVVNQDADKAESKKRSKQKIKVAVEEKDSDVIVHGYIKKLGGPFTSAWQTKYGKLYPSRLELYPESLTAKPELVFMDQIEDVCAEMQTIKGETAIIVKLRDGFKEPKICLTNSDEISLKEWHTSLRTAHKVSQELLQRMGRKAIKIYGVNHDPMLSESERPGSVTRAFLNRASSVDSGV", "output": "Specifically phosphorylates the activated forms of G protein-coupled receptors (By similarity). Required in adult sensory neurons for chemotaxis . Plays a role in the ASH sensory neurons in the chemotaxis response to NaCl where it is likely to modulate the strength of the NaCl avoidance response which occurs at high NaCl concentrations . Required in the HSN motor neurons for normal egg laying by promoting phosphorylation of amine oxidase amx-2 which inhibits amx-2 activity, preventing metabolism of serotonin . Acts in head acetylcholine neurons to positively regulate locomotion . Inactivates dopamine receptor dop-3 which leads to inactivation of guanine nucleotide-binding protein G(o) subunit goa-1 and activation of the unc-77/nca-1 and nca-2 ion channel proteins ."}]}
+{"id": "function_test_287", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAVPKESIPSLLECQCQICVEILFEPVTLPCNHTLCKPCFESTVEKASLCCPFCRRRVSSWARYRSRTNSLVNMELWEIIQKHYPKECKLRASGQESKEIVDDYQPVRLLSKPGELRREYEEEISKVEAERRACEEEENKASEEYIQKLLAEEEEEEKRQAEKRHREMEEQLKSDEELARRLSLDINNFCEGSVLASPLNSRKSDPVTTKSQKKSKNKQTNTGDIQKYLSPKSQLGSASQSEVVQEDRKSSMSKKIDDNSDVKSPTWQDTEVEEDMPTLSPQIYLEVQEQGAKSSVESPMPQLYTSDGEWYLEGKVETGPSNHEKGLCVINLEEPKARVPYSGDAATEPCGETESECTVSYMTQFLRNNTVGTENEESHLQISKGTSKRRNLEPLSEAIREPCFSAKRRKMFPKASSDQEETEISLTQKLIDLEHLLFERHKQEKQDRLLALQLQEEVDQEQMRPDRQKGSPDGYQLRTVSSPPDKVLNGQRKNSRDRNSKRQTELEQPKPRTDSKNENHQQPSFKIQLKCSVNRRKIANSTNDNCNVSKTAHSLQPSKSQKSIFQMFQRVTK", "output": "E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recruited at DNA interstrand cross-links (ICLs) sites and promotes accumulation of 'Lys-63'-linked ubiquitination of histones H2A and H2AX, leading to recruitment of FAAP20 and Fanconi anemia (FA) complex, followed by interstrand cross-link repair. H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Also involved in class switch recombination in immune system, via its role in regulation of DSBs repair. Following DNA damage, promotes the ubiquitination and degradation of JMJD2A/KDM4A in collaboration with RNF8, leading to unmask H4K20me2 mark and promote the recruitment of TP53BP1 at DNA damage sites. Not able to initiate 'Lys-63'-linked ubiquitination in vitro; possibly due to partial occlusion of the UBE2N/UBC13-binding region. Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively)."}]}
+{"id": "function_test_288", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MERNKFASKMSQHYTKTICIAVVLVAVLFSLSSAAAAGSGAAVSVQLEALLEFKNGVADDPLGVLAGWRVGKSGDGAVRGGALPRHCNWTGVACDGAGQVTSIQLPESKLRGALSPFLGNISTLQVIDLTSNAFAGGIPPQLGRLGELEQLVVSSNYFAGGIPSSLCNCSAMWALALNVNNLTGAIPSCIGDLSNLEIFEAYLNNLDGELPPSMAKLKGIMVVDLSCNQLSGSIPPEIGDLSNLQILQLYENRFSGHIPRELGRCKNLTLLNIFSNGFTGEIPGELGELTNLEVMRLYKNALTSEIPRSLRRCVSLLNLDLSMNQLAGPIPPELGELPSLQRLSLHANRLAGTVPASLTNLVNLTILELSENHLSGPLPASIGSLRNLRRLIVQNNSLSGQIPASISNCTQLANASMSFNLFSGPLPAGLGRLQSLMFLSLGQNSLAGDIPDDLFDCGQLQKLDLSENSFTGGLSRLVGQLGNLTVLQLQGNALSGEIPEEIGNMTKLISLKLGRNRFAGHVPASISNMSSLQLLDLGHNRLDGVFPAEVFELRQLTILGAGSNRFAGPIPDAVANLRSLSFLDLSSNMLNGTVPAALGRLDQLLTLDLSHNRLAGAIPGAVIASMSNVQMYLNLSNNAFTGAIPAEIGGLVMVQTIDLSNNQLSGGVPATLAGCKNLYSLDLSGNSLTGELPANLFPQLDLLTTLNISGNDLDGEIPADIAALKHIQTLDVSRNAFAGAIPPALANLTALRSLNLSSNTFEGPVPDGGVFRNLTMSSLQGNAGLCGGKLLAPCHGHAAGKKRVFSRTGLVILVVLIALSTLLLLMVATILLVSYRRYRRKRRAADIAGDSPEAAVVVPELRRFSYGQLAAATNSFDQGNVIGSSNLSTVYKGVLAGDADGGMVVAVKRLNLEQFPSKSDKCFLTELATLSRLRHKNLARVVGYAWEAGKIKALVLDYMVNGDLDGAIHGGAAAPPPAPSRWTVRERLRVCVSVAHGLVYLHSGYDFPVVHCDVKPSNVLLDGDWEARVSDFGTARMLGVHLPAAANAAAQSTATSSAFRGTVGYMAPEFAYMRTVSTKVDVFSFGVLAMELFTGRRPTGTIEEDGVPLTLQQLVDNAVSRGLDGVHAVLDPRMKVATEADLSTAADVLAVALSCAAFEPADRPDMGAVLSSLLKMSKLVGED", "output": "Constitutes the pattern-recognition receptor (PPR) that determines the specific perception of flagellin (flg22), a potent elicitor of the defense response to pathogen-associated molecular patterns (PAMPs). Recognizes flg22 from Pseudomonas aeruginosa and Acidovorax avenae. flg22 is a peptide derived from the bacterial flagellin N-terminus sequence . Does not recognize flg22 from Xanthomonas oryzae pv. oryzae (Xoo) or Xanthomonas oryzae pv. oryzicola (Xoc) ."}]}
+{"id": "function_test_289", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLVLLAFIIVFHITSAALLLVATIDNAWWVGEEFFADIWKVCVNNTNCTELNDSVQDFSTVQAVQATMILSTILCCIAFLIFLLQLFRLKQGERFVLTSIIQLMACLCVMIAASIYTDRRKDIHEKNEELYAQTSGGSFGYSFILAWVAFAFTFISGLMYLILRKRK", "output": "Functions as a key regulator of cell membrane composition by regulating protein surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion. Regulates transepithelial migration of neutrophils into the alveolar lumen, potentially via mediation of cell surface expression of adhesion markers and lipid raft formation (By similarity). Negatively regulates caveolae formation by reducing CAV1 expression and CAV1 amount by increasing lysosomal degradation (By similarity). Facilitates surface trafficking and the formation of lipid rafts bearing GPI-anchor proteins (By similarity). Regulates surface expression of MHC1 and ICAM1 proteins increasing susceptibility to T-cell mediated cytotoxicity (By similarity). Regulates the plasma membrane expression of the integrin heterodimers ITGA6-ITGB1, ITGA5-ITGB3 and ITGA5-ITGB1 resulting in modulation of cell-matrix adhesion (By similarity). Also regulates many processes through PTK2 (By similarity). Regulates blood vessel endothelial cell migration and angiogenesis by regulating VEGF protein expression through PTK2 activation (By similarity). Regulates cell migration and cell contraction through PTK2 and SRC activation (By similarity). Regulates focal adhesion density, F-actin conformation and cell adhesion capacity through interaction with PTK2. Positively regulates cell proliferation (By similarity). Plays a role during cell death and cell blebbing (By similarity). Promotes angiogenesis and vasculogenesis through induction of VEGFA via a HIF1A-dependent pathway (By similarity). Also plays a role in embryo implantation by regulating surface trafficking of integrin heterodimer ITGA5-ITGB3 (By similarity). Plays a role in placental angiogenesis and uterine natural killer cell regulation at the maternal-fetal placental interface, however not required in the maternal tissues for a viable pregnancy (By similarity). Involved in the early stages of embryogenic development and cardiogenesis, potentially via regulation of epithelial-mesenchymal transition timing (By similarity). May play a role in glomerular filtration (By similarity)."}]}
+{"id": "function_test_290", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAAGQNGHEEWVGSAYLFLESAVDKVILSEAYTDPKKKVAIYKALQTALSESGDSSDVLQILKIHCSDPQLIVQLRFCGRVLCGRFLQAYREGALRTALQRCMAPALAQEALRLQLELRAGAEQLDSWLTDEERCLNYILAQKPDRLRDEELAELEDELCKLTCDCTGQGGAIQVASAGSKFPVSSPTEEKPLPAACQTFLFHGQLVVNRPLTLQDQQTFARSVGLKWRRVGRSLQRNCRALRDPALDSLAYEYERDGLYEQAFQLLRRFMQAEGRRATLQRLVEALEENELTSLAEDLLGQAEPDGGLA", "output": "Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD (By similarity). Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B (By similarity). The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A ."}]}
+{"id": "function_test_291", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSGTNNVAQARKLVEQLRIEAGIERIKVSKASSDLMGYCEQHARNDPLLVGVPASENPFKDKKPCIIL", "output": "Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf) subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum."}]}
+{"id": "function_test_292", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGPRALSPLASLRLRWLLACGLLGPVLEAGRPDLEQTVHLSSYEIITPWRLTRERREALGPSSQQISYVIQAQGKQHIIHLERNTDLLPNDFVVYTYDKEGSLLSDHPNVQSHCHYRGYVEGVQNSAVAVSACFGLRGLLHLENASFGIEPLHNSSHFEHIFYPMDGIHQEPLRCGVSNRDTEKEGTQGDEEEHPSVTQLLRRRRAVLPQTRYVELFIVVDKERYDMMGRNQTAVREEMIRLANYLDSMYIMLNIRIVLVGLEIWTDRNPINIIGGAGDVLGNFVQWREKFLITRWRHDSAQLVLKKGFGGTAGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGHNLGMNHDDGRECFCGAKSCIMNSGASGSRNFSSCSAEDFEKLTLNKGGSCLLNIPKPDEAYSAPSCGNKLVDPGEECDCGTAKECEVDPCCEGSTCKLKSFAECAYGDCCKDCQFLPGGSMCRGKTSECDVPEYCNGSSQFCPPDVFIQNGYPCQNSKAYCYNGMCQYYDAQCQVIFGSKAKAAPRDCFIEVNSKGDRFGNCGFSGSEYKKCATGNALCGKLQCENVQDMPVFGIVPAIIQTPSRGTKCWGVDFQLGSDVPDPGMVNEGTKCDAGKICRNFQCVNASVLNYDCDIQGKCHGHGVCNSNKNCHCEDGWAPPHCDTKGYGGSVDSGPTYNAKSTALRDGLLVFFFLIVPLVAAAIFLFIKRDELRKTFRKKRSQMSDGRNQANVSRQPGDPSISRPPGGPNVSRPPGGPGVSRPPGGPGVSRPPGGPGVSRPPPGHGNRFPVPTYAAKQPAQFPSRPPPPQPKISSQGNLIPARPAPAPPLYSSLT", "output": "Cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5 . May mediate cell-cell, cell-matrix interactions and regulate the motility of cells via interactions with integrins ."}]}
+{"id": "function_test_293", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MMLRWSGVWGFHPPRIFPSLLVVVALVGLLPVLRSHGLQHSPTASTIRGSEPPRERSIGDVTTAPSEPLHRPDDHNLTNLIIEHGGKPSRKAFPVLDIDYPHVRTPFEISLWILLACLMKIGFHVIPTISSIVPESCLLIVVGLLVGGLIKGVGETPPFLQSDVFFLFLLPPIILDAGYFLPLRQFTENLGTILIFAVVGTLWNAFFLGGLLYAVCLVGGEQINNIGLLDTLLFGSIISAVDPVAVLAVFEEIHINELLHILVFGESLLNDAVTVVLYHLFEEFASYDSVGISDIFLGFLSFFVVALGGVFVGVVYGVIAAFTSRFTSHIRVIEPLFVFLYSYMAYLSAELFHLSGIMALIASGVVMRPYVEANISHKSHTTIKYFLKMWSSVSETLIFIFLGVSTVAGSHQWNWTFVISTLLFCLIARVLGVLVLTWFINKFRIVKLTPKDQFIIAYGGLRGAIAFSLGYLLDKKHFPMCDLFLTAIITVIFFTVFVQGMTIRPLVDLLAVKKKQETKRSINEEIHTQFLDHLLTGIEDICGHYGHHHWKDKLNRFNKKYVKKCLIAGERSKEPQLIAFYHKMEMKQAIELVESGGMGKIPSAVSTVSMQNIHPKAVTSDRILPALSKDKEEEIRKILRSNLQKTRQRLRSYNRHTLVADPYEEAWNQMLLRRQKARQLEQKITNYLTVPAHKLDSPTLSRARIGSDPLAYEPKADLPVITIDPASPQSPESVDLVNEELKGKVLGLNRGPRVTPEEEEEDEDGIIMIRSKEPSSPGTDDVFTPGSSDSPSSQRIQRCLSDPGPHPEPGEGEPFIPKGQ", "output": "Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction."}]}
+{"id": "function_test_294", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIHMLNAAAYRVKWTRSGAAKRAACLVAAAYALKTLYPIIGKRLKQPGHRKAKAEAYSPAENREILHCTEIICKKPAPGLNAAFFKQLLELRKILFPKLVTTETGWLCLHSVALISRTFLSIYVAGLDGKIVKSIVEKKPRTFIIKLIKWLMIAIPATFVNSAIRYLECKLALAFRTRLVDHAYETYFANQTYYKVINMDGRLANPDQSLTEDIMMFSQSVAHLYSNLTKPILDVILTSYTLIRTATSRGASPIGPTLLAGLVVYATAKVLKACSPKFGSLVAEEAHRKGYLRYVHSRIIANVEEIAFYRGHKVEMKQLQKCYKALAYQMNLILSKRLWYIMIEQFLMKYVWSSCGLIMVAIPIITATGFADGDLEDGPKQAMVSDRTEAFTTARNLLASGADAIERIMSSYKEITELAGYTARVYNMFWVFDEVKRGIYKRTVTQEPENHSKRGGNLELPLSDTLAIKGTVIDVDHGIICENVPIITPAGEVVASRLNFKVEEGMHLLITGPNGCGKSSLFRILSGLWPVYEGVLYKPPPQHMFYIPQRPYMSLGSLRDQVIYPDSADDMREKGYTDQDLERILHSVHLYHIVQREGGWDAVMDWKDVLSGGEKQRMGMARMFYHKPKYALLDECTSAVSIDVEGKIFQAAIGAGISLLSITHRPSLWKYHTHLLQFDGEGGWRFEQLDTAIRLTLSEEKQKLESQLAGIPKMQQRLNELCKILGEDSVLKTIQTAEKTS", "output": "ATP-dependent transporter of the ATP-binding cassette (ABC) family involved in the transport of very long chain fatty acid (VLCFA)-CoA from the cytosol to the peroxisome lumen (By similarity). Like ABCD1 seems to have fatty acyl-CoA thioesterase (ACOT) and ATPase activities, according to this model, VLCFA-CoA as free VLCFA is transpoted in an ATP-dependent manner into peroxisomes after the hydrolysis of VLCFA-CoA mediated by the ACOT activity of ABCD2 (By similarity). Shows overlapping substrate specificities with ABCD1 toward saturated fatty acids (FA) and monounsaturated FA (MUFA) but has a distinct substrate preference for shorter VLCFA (C22:0) and polyunsaturated fatty acid (PUFA) such as C22:6-CoA and C24:6-CoA (in vitro) (By similarity). Thus, may play a role in regulation of VLCFAs and energy metabolism namely, in the degradation and biosynthesis of fatty acids by beta-oxidation ."}]}
+{"id": "function_test_295", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGLLWYLMSLSFYGILQSHASERCDDWGLDTMRQIQVFEDEPARIKCPLFEHFLKYNYSTAHSSGLTLIWYWTRQDRDLEEPINFRLPENRISKEKDVLWFRPTLLNDTGNYTCMLRNTTYCSKVAFPLEVVQKDSCFNSAMRFPVHKMYIEHGIHKITCPNVDGYFPSSVKPSVTWYKGCTEIVDFHNVLPEGMNLSFFIPLVSNNGNYTCVVTYPENGRLFHLTRTVTVKVVGSPKDALPPQIYSPNDRVVYEKEPGEELVIPCKVYFSFIMDSHNEVWWTIDGKKPDDVTVDITINESVSYSSTEDETRTQILSIKKVTPEDLRRNYVCHARNTKGEAEQAAKVKQKVIPPRYTVELACGFGATVFLVVVLIVVYHVYWLEMVLFYRAHFGTDETILDGKEYDIYVSYARNVEEEEFVLLTLRGVLENEFGYKLCIFDRDSLPGGIVTDETLSFIQKSRRLLVVLSPNYVLQGTQALLELKAGLENMASRGNINVILVQYKAVKDMKVKELKRAKTVLTVIKWKGEKSKYPQGRFWKQLQVAMPVKKSPRWSSNDKQGLSYSSLKNV", "output": "Coreceptor for IL1RL2 in the IL-36 signaling system. Coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Recruits TOLLIP to the signaling complex. Does not bind to interleukin-1 alone; binding of IL1RN to IL1R1, prevents its association with IL1R1 to form a signaling complex. The cellular response is modulated through a non-signaling association with the membrane IL1R2 decoy receptor. Secreted forms (isoforms 2 and 3) associate with secreted ligand-bound IL1R2 and increase the affinity of secreted IL1R2 for IL1B; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors. Coreceptor for IL1RL1 in the IL-33 signaling system. Can bidirectionally induce pre- and postsynaptic differentiation of neurons by trans-synaptically binding to PTPRD . May play a role in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells (By similarity).; "}]}
+{"id": "function_test_296", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKGSRTITATPEGSPEAVDLSLIGLPPPMSQRPGSASATRSIFRSMSVATGSEPRKKALEATGPGGPRAINNLRRSNSTTQVNQSWTGSPRPAEPTDFLMLFEGSTSGRRRVASLSKASSEKEATWNVLDEQPRGLALPASAQSPSTLDSALGPRRKECPLAPSFTANNRSNKGAVGNCVTTMVHNHYASSKMVSPPKSSNQTAPSLNNIVKAAAREGGEGSDLGKPRKNLSSASQSARGTTGLLRRREVTEEEAERFIHQVNQAAVTIQRWYRCQVQRRRAGAAALEHLLASKREGQRQRLGGGNLLELHRQEEAARKKAREEKARQARQAAIQVLQQKRAQKASEAEHRRPKDRPETRAPEQPRPMQEPGCVTHPKANNAGASIYPTGPADPCPPASESSPEQWQSPEDKPQDIHSQGEARQDLAVSGSSRGKARARATLDDLLDTLKLLEEEPEPLPHPKAYHKDRYAWTDEEEDANSLTADNLEKFGKLSAAPGPPDDGTLLSEAKLQSIMTFLDEMEKSGQERPAPWRESLVLEAGSGSEGSTSVMRLKLELEEKKQAMALLQRALAQQRDLTVRRVKETEKELTRQLRQQKEQYEATIQRHLSFIDQLIEDKKVLSEKCEAVVAELKHGDQRCRERVAQMQEQHELEIKKLKELMSATEKIRREKWINEKTKKIKEITVRGLEPEIQKLIAKHKQEVRRLRGLHEAELQQREEQAAQRHLRQAEELRQHLDREREVLGQQERERAQQRFEQHLEQEQRALEQQRRRLYNEVAEEKERLGQQAARQRAELEELRQQLEESSAALTRALRAEFERSREEQERRHQMELKALKDQLEAERQAWVASCAKKEEAWLLTRERELKEEIRKGRDQEIELVIHRLEADMTLAKEESERAAESRVKRVRDKYETELSELEQSERKLQERCSELKGRLGEAEGEKERLQSLVRQKEKELEDLRAVNTQMCSERASLAQVVRQEFAEQLAASQEETQRVKVELAELQARQQVELDEVHRRVKTALARKEAAVNSLRKQHEAAVKRADHLEELLEQHKGSSLSSK", "output": "Component of centriolar satellites contributing to the building of a complex and dynamic network required to regulate cilia/flagellum formation. In proliferating cells, MIB1-mediated ubiquitination induces its sequestration within centriolar satellites, precluding untimely cilia formation initiation. In contrast, during normal and ultraviolet or heat shock cellular stress-induced ciliogenesis, its non-ubiquitinated form is rapidly displaced from centriolar satellites and recruited to centrosome/basal bodies in a microtubule- and p38 MAPK-dependent manner. Acts also as a negative regulator of BBSome ciliary trafficking (By similarity). Plays a role in sperm flagellar formation; may be involved in the regulation of intraflagellar transport (IFT) and/or intramanchette (IMT) trafficking, which are important for axoneme extension and/or cargo delivery to the nascent sperm tail . Required for optimal cell proliferation and cell cycle progression; may play a role in the regulation of genome stability and centriole duplication in non-ciliogenic cells (By similarity). Involved in centriole duplication . Required for CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2 (By similarity). Essential for maintaining proper centriolar satellite integrity (By similarity)."}]}
+{"id": "function_test_297", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRSLLLLASLAWLLLAQAKDDAKLEDNLLVLTVATKETEGFRRFKRSAQFFNYKIQSLGLGEDWSAAGGPSAAGGGQKVRLLKKALKKYADKEDLVILFVDSYDVVFASGPRELLKKFQQAKSRVVFSAEELIYPDRRLEAKYPTVPDGKRFLGSGGFIGYAPSLSKLVAEWEGQDNDSDQLFYTKIFLDPEKREQINISLDHRCRIFQNLDGALDEVVLKFEMGHVRARNLAYDTLPVVIHGNGPTKLQVNYLGNYIPRFWTFETGCTVCDEGLRSLKGIGDEALPTVLVGVFIEQPTPFLSLFFRRLLHLRYPQKQMRLFIHNQEQHHKLQVEQFLAEHGGEYQSVKLVGPEVRMANADARNMGADLCRQDQTCTYYFSVDADVALTEPNSLRLLIEQNKNVIAPLMTRHGRLWSNFWGALSADGYYARSEDYVDIVQGRRVGVWNVPYISNIYLIKGSALRAELRHVDLFHYSKLDPDMSFCANVRQQEVFMFLTNRHTFGHLLSLDNYQTTHLHNDLWEVFSNPQDWKEKYIHENYTKALAGKLVETPCPDVYWFPIFTEVACDELVEEMEHYGQWSLGDNKDNRIQGGYENVPTIDIHMNQITFEREWHKFLVEYIAPLTEKLYPGYYTKAQFDLAFVVRYKPDEQPSLMPHHDASTFTINIALNRVGEDYEGGGCRFLRYNCSVRAPRKGWALMHPGRLTHYHEGLPTTKGTRYIAVSFVDP", "output": "Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils (By similarity). Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens . These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links (By similarity)."}]}
+{"id": "function_test_298", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNHCLVVSHKKLQTFRTFAASKFSSFTKSAQKSIKYSFQFIYQNNPLFVHVAYFALISFAGYGSLKVLKPRDKSNTLKDLDVLFTSVSASTVSSMATVEMEDFSSAQLWVLTILMLIGGEVFTSMLGIHFMRAEFGTKESVSTRDHSPCIDIESITSTKFGPSTQGTKVTVSFSELRMENGGHVEPKTIKFLGFVVMGYLLITNLGGSLLIYLYLNLVPSAHKILKRKGIGIIVFSVFTAISSVGNCGFTPVNENMIIFQKNSILLLLILPQILAGNTLFAPCLRLMVWSLEKITGKKDCRYILEYPKAIGYKHLMSTRESVYLTLTVVSLIILQTVLFLSLEWSSVALDGMSNYQKIVSALFQSVNARHAGESVTDLSNLSSAILVLYTIMMYLPGYTSFLPRHDGEDSKTEKINKRKGLLENWIFSHMSYLAIFVMLICITERDSMATDPLNFNVFSILFEVVSAYGNVGFSVGYSCKRLLNHDARCKDASYGFAGKWSDNGKAILIIVMLFGRLKTFNMKGGRAWKLR", "output": "Functions as a highly-selective sodium transporter . Does not seem to function as sodium-potassium cotransporter . May be involved in turgor changes for rolling and unrolling of leaves in response to environmental variations ."}]}
+{"id": "function_test_299", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAPPMTNCLTFSLSPMEMLKSTDQSHFSSSYDDSSTPYLIDNFYAFKEEAEIEAAAASMADSTTLSTFFDHSQTQIPKLEDFLGDSFVRYSDNQTETQDSSSLTPFYDPRHRTVAEGVTGFFSDHHQPDFKTINSGPEIFDDSTTSNIGGTHLSSHVVESSTTAKLGFNGDCTTTGGVLSLGVNNTSDQPLSCNNGERGGNSNKKKTVSKKETSDDSKKKIVETLGQRTSIYRGVTRHRWTGRYEAHLWDNSCRREGQARKGRQVYLGGYDKEDRAARAYDLAALKYWGSTATTNFPVSSYSKELEEMNHMTKQEFIASLRRKSSGFSRGASIYRGVTRHHQQGRWQARIGRVAGNKDLYLGTFATEEEAAEAYDIAAIKFRGINAVTNFEMNRYDIEAVMNSSLPVGGAAAKRHKLKLALESPSSSSSDHNLQQQQLLPSSSPSDQNPNSIPCGIPFEPSVLYYHQNFFQHYPLVSDSTIQAPMNQAEFFLWPNQSY", "output": "Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways."}]}
+{"id": "function_test_300", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEEERRDDYKFLRIQDAFKALHLHVNLIGVIVELGFSNGSDCSCTLKIVDPWYSGSGLPVKFVARTIRDLPRVESIGDIILLSRVKIVLINRKITALCNETTSSSFALFNGKHSVDSIPYQSSPKFLMREQDKNFLSNLREWMITYKFEDGSCCFTSLKDIKEGECSNLSCQIVHISKVYKDRWYLFVWDGTEMPPCNILVKSERLPLCVEPEMLPTYMLRKFPTFGSVLRIIVDRVSEKQAIHCLQPGQHVKLLNLFFQVNMGLWNATFTPSTKMQYTMSREMEAFSPQRMCGEKFSPRWNPIARCISRSHSEITGVAHDDAPFVSLMDILTYHNVTAKFRCVVRFIQVYPRDVRKLRDINGNIKLVAILEDATARIHASLYADEGEKFFGCDESDEEALVKKLNRLLGGEEMEKVPRNPPWVQCCLFSFYKHKMDQWESRRFRIFDTWINAS", "output": "Negatively regulates telomerase activity and participates in chromosome end protection . Binds RNA non-specifically . Associates with a regulatory Pol III-dependent lncRNA, which represses telomerase activity in response to DNA damage . Binds single-stranded telomeric DNA with weak affinity ."}]}
+{"id": "function_test_301", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKILLYIAIILSFFSLITISSECKIAVLLSGSPNDLGYNYLMNEARVKAESELKLDFSIYYENLEESMEEAEKAFQDALHKGANLIVVGSFVHVGLGLKYAALTKDQDIYWIIRGNKRPNPDLPHVVILNFNSFELHYLLGYFSGLMTKTGIVGFVAPGPDVNTISTDNSFYLGAKYARPNITFLNVYVQSWYNPNVSYSAAKMLIKNGADLIGMSQDDMSCQKAMMDSGLIGIGATGYPTHLLFGGNVGVSYITNWTNLYVKYAQHVLNDDWPDYSSYFTNLSREDSIFIDDYSYKVPIDIQNLVNDEIQRLKNTSYIPYRSDPYLAQLGIPFDSKGLLVEDQFRANKKLLKGDSISKVIDFGQYSIPIEFIDYPNSLKYGVTIVSGVCIFICLVCMTLVVVFKKARVIKSSSPAFLLLILLGCCIIFAACILFAQSPTNQTCSARIWLLSLGYTLFLGNLLVKNWRIWLLFDNPKLKKRAITNWKLYPWVFAILAIDVMILAIWQGLGNINAESRIGYDSLTQYQYKNVCSSDDQGSIALYLLLVFHGLVLLVACFISFKIKVVDIEEFNESKPITTSVYIITFCLFIVIPLMVSPQSLTSQTTIICVCAIVTTLISMLLLFGSKFYKMATQGLAINETFATSTKSSSKSSKSSYGKDNPNPNAINFGEDDTSDETSEEKHKSPKQKSVNFSNKSNSHLAVFTSDEETSKTSKLSIDFENSSKDISIDQLQQQKQQPINTNGDLENKSNDKIDDDNDNSSVLSKRISNQQNGETEIDSNNV", "output": "May act during the development and be a negative regulator."}]}
+{"id": "function_test_302", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MYGGDEVSAIVVDLGSHTCKAGYAGEDAPKAVFPSVIGAVDGVEAMDVDVDSTKTNSNSEDSKTESEKEKSKRKLYVGSQAMSYRRDHMEVLSPIKDGIVSDWDLVDNIWEHAFKSCLMIDPTEHPMLLAEPPLNTQQQREKAAELMFEKYKVPALFMAKNPVLTSFATGRATSLVVDCGGGSTTISPVHDGYVLQKAVVSSPLGGEFLTDCLLKSLESKGIKIRPRYSFKRKEVRAGEFQVEDVDIPDTTESYKLFCQRMIVGDIKDSICRVPDTPYDDKSYSNIPTTSYELPDGQTLEIGADRFKVPDVMFNPSIVQTIPGMEKYAEMIPSVRGLPHMVMESINKCDVDIRRELYSSILLAGGTSSMQQLKERLEKDLIEESPHSARVKVLASGNTTERRFSVWIGGSILASLGSFQQMWFSKSEYEEHGASYIQRKCP", "output": "Involved in several developmental processes including organization of plant organs, flowering time, anther development, flower senescence and fertility, probably by regulating the chromatin structure."}]}
+{"id": "function_test_303", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEAEGVAVAAAAAAAAAAATIIASDDCDSRPGQELLVAWNTVSTGLVPPAALGLASSRTSGAVPPKEEELRAAVEVLRGHGLHSVLEEWFVEVLQNDLQGNIATEFWNAIALRENSVDEPQCLGLLLDAFGLLESRLDPYLHSLELLEKWTRLGLLMGAGAQGLREKVHTMLRGVLFFSTPRTFQEMVQRLYGRFLRVYMQSKRKGEGGTDPELEGELDSRYARRRYYRLLQSPLCAGCGSDKQQCWCRQALEQFNQLSQVLHRLSLLERVCAEAVTTTLHQVTRERMEDRCRGEYERSFLREFHKWIERVVGWLGKVFLQDNPTRPTSPEAGNTLRRWRCHVQRFFYRIYATLRIEELFSIIRDFPDSRPAIEDLKYCLERTDQRQQLLVSLKVALETRLLHPGVNTCDIITLYISAIKALRVLDPSMVILEVACEPIRRYLRTREDTVRQIVAGLTGDSDGTGDLAVELSKTDPACLETGQDSEDDSGEPEDWVPDPVDADPVKSSSKRRSSDIISLLVSIYGSKDLFINEYRSLLADRLLHQFSFSPEREIRNVELLKLRFGEAPMHFCEVMLKDMADSRRINANIREEDEKRPVEEQPPFGVYAVILSSEFWPPFKDEKLEVPEDIRAALDVYCKKYEKLKAMRTLSWKHTLGLVTMDVELADRTLSVAVTPVQAVVLLYFQNQASWTLEELSKVVKMPVALLRRRMSVWLQQGVLREEPPGTFSVIEEERPQDRDNMVLIDSDDESDSGMASQADQKEEELLLFWAYIQAMLTNLESLSLERIYSMLRMFVMTGPALAEIDLQELQGYLQKKVRDQQLIYSAGVYRLPKNSN", "output": "Together with the RING-H2 protein ANAPC11, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 drives presynaptic differentiation."}]}
+{"id": "function_test_304", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "SLPSLLTRLEQMPDYSIFRGYIIHYNLASAIESADAYTVFVPNNEAIENYIREKKATSLKEDILRYHVVLGEKLLKNDLHNGMHRETMLGFSYLLAFFLRNDQLYVNEAPINYTNVATDKGVIHGLEKVLEIQKNRCDNNDTIIVRGECGKCSQQAPCPLETKPLRETRKCIYSIYFMGKRSVFIGCQPQCVRTIITRACCAGFFGPQCQACPGRGQNVCSGNGFCLDGVNGTGTCQCGLGFNGTACETCTEGKYGIHCDQACSCVHGRCSQGPLGDGSCDCDVGWRGVKCDMEITTDNCNGTCHTSANCLLDPDGKASCKCAAGFRGNGTVCTAINACETSNGGCSTKADCKRTTPGNRVCVCKAGYTGDGIVCLEINPCLENHGGCDRNAECTQTGPNQAVCNCLPKYTGDGKVCSLINVCLTNNGGCSPFAFCNYTEQDQRICTCKPDYTGDGIVCRGSIYGELPKNPSTSQYFFQLQEHAVRELAGPGPFTVFAPLSSSFNHEPRIKDWDQQGLMSQVLRYHVVGCQQLLLDNLKVTTSATTLQGEPVSISVSQDTVFINNEAKVLSSDIISTNGVIHVIDKLLSPKNLLITPKDALGRVLQNLTTVAANHGYTKFSKLIQDSGLLSVITDSIHTPVTVFWPTDKALEALPPEQQDFLFNQDNKDKLKSYLKFHVIRDSKALASDLPRSASWKTLQGSELSVRCGTGSDIGELFLNEQMCRFIHRGLLFDVGVAYGIDCLLMNPTLGGRCDTFTTFDIPGECGSCIFTPKCPLKSKPKGVKKKCIYNPLPFRRNVEGCQNLCTVVIQTPRCCHGYFMPDCQACPGGPDTPCNNRGMCRDLYTPMGQCLCHTGFNGTACELCWHGRFGPDCQPRSCSEHGQCDEGITGSGECLCETGWTAASCDTPTAVFAVCTPACSVHATCTENNTCVCNLNYEGDGITCTVVDFCKQNNGGCAKVAKCSQKGTQVSCSCKKGYKGDGYSCIEIDPCADGVNGGCHEHATCRMTGPGKHKCECKSHYVGDGVDCEPEQLPLDRCLQDNGQCHPDASCADLYFQDTTVGVFHLRSPLGQYKLTFDKAKEACAKEAATIATYNQLSYAQKAKYHLCSAGWLESGRVAYPTTYASQKCGANVVGIVDYGSRANKSEMWDVFCYRMKDVNCTCKAGYVGDGFSCSGNLLQVLMSFPSLTNFLTEVLAFSKSSARGQAFLKHLTDLSIRGTLFVPQNSGLPGNKSLSGRDIEHHLTNVNVSFYNDLVNGTFLRTMLGSQLLITFSQDQLHQETRFVDGRSILQWDIIAANGILHIISEPLRAPPTAATAAHSGLGTGIFCAVVLVTGAIALAAYSYFRLKQRTTGFQRFDQKRTLMSWLLASSSPRISQTLCMRPQRRHPQSPPVTPSQTLENRIWRTATLWGHCGPDMRSQQATTVTVPR", "output": "Phosphatidylserine receptor that enhances the engulfment of apoptotic cells. Hyaluronan receptor that binds to and mediates endocytosis of hyaluronic acid (HA). Acts also, in different species, as a primary systemic scavenger receptor for heparin (Hep), chondroitin sulfate (CS), dermatan sulfate (DS), nonglycosaminoglycan (GAG), acetylated low-density lipoprotein (AcLDL), pro-collagen propeptides and advanced glycation end products (AGE). May serve to maintain tissue integrity by supporting extracellular matrix turnover or it may contribute to maintaining fluidity of bodily liquids by resorption of hyaluronan. Counter receptor which plays an important role in lymphocyte recruitment in the hepatic vasculature. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. The proteolytically processed 175 kDa form also functions as an endocytosis receptor for heparin internalization as well as HA and CS."}]}
+{"id": "function_test_305", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNLEEKPTMTASRASPQAEHLYYVRCSICNTILAVGIPLKRMLDTVTVKCGHCGNLSFLTTTPPLQGHVSLTLQMQSFGGSDYKKGSSSSSSSSTSSDQPPSPSPPFVVKPPEKKQRLPSAYNRFMRDEIQRIKSANPEIPHREAFSAAAKNWAKYIPNSPTSITSGGHNMIHGLGFGEKK", "output": "Transcription factor required for the initiation of nectary development. Also involved in suppressing early radial growth of the gynoecium, in promoting its later elongation and in fusion of its carpels by regulating both cell division and expansion. Establishes the polar differentiation in the carpels by specifying abaxial cell fate in the ovary wall. Regulates both cell division and expansion."}]}
+{"id": "function_test_306", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MATVSSSSWPNPNPNPDSTSASDSDSTFPSHRDRVDEPDSLDSFSSMSLNSDEPNQTSNQSPLSPPTPNLPVMPPPSVLHLSFNQDHACFAVGTDRGFRILNCDPFREIFRRDFDRGGGVAVVEMLFRCNILALVGGGPDPQYPPNKVMIWDDHQGRCIGELSFRSDVRSVRLRRDRIIVVLEQKIFVYNFSDLKLMHQIETIANPKGLCAVSQGVGSMVLVCPGLQKGQVRIEHYASKRTKFVMAHDSRIACFALTQDGHLLATASSKGTLVRIFNTVDGTLRQEVRRGADRAEIYSLAFSSNAQWLAVSSDKGTVHVFGLKVNSGSQVKDSSRIAPDATPSSPSSSLSLFKGVLPRYFSSEWSVAQFRLVEGTQYIAAFGHQKNTVVILGMDGSFYRCQFDPVNGGEMSQLEYHNCLKPPSVF", "output": "The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Required for autophagy by autophagosome formation during nutrient deprivation, senescence and under abiotic stresses, including oxidative, high salt and osmotic stress conditions. Cooperates with jasmonate- and WRKY33-mediated signaling pathways in the regulation of plant defense responses to necrotrophic pathogens."}]}
+{"id": "function_test_307", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MADPAIKLFGKTIPLPELGVVDSSSSYTGFLTETQIPVRLSDSCTGDDDDEEMGDSGLGREEGDDVGDGGGESETDKKEEKDSECQEESLRNESNDVTTTTSGITEKTETTKAAKTNEESGGTACSQEGKLKKPDKILPCPRCNSMETKFCYYNNYNVNQPRHFCKKCQRYWTAGGTMRNVPVGAGRRKNKSPASHYNRHVSITSAEAMQKVARTDLQHPNGANLLTFGSDSVLCESMASGLNLVEKSLLKTQTVLQEPNEGLKITVPLNQTNEEAGTVSPLPKVPCFPGPPPTWPYAWNGVSWTILPFYPPPAYWSCPGVSPGAWNSFTWMPQPNSPSGSNPNSPTLGKHSRDENAAEPGTAFDETESLGREKSKPERCLWVPKTLRIDDPEEAAKSSIWETLGIKKDENADTFGAFRSSTKEKSSLSEGRLPGRRPELQANPAALSRSANFHESS", "output": "Transcription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). Regulates a photoperiodic flowering response. Transcriptional repressor of 'CONSTANS' expression. The stability of CDF2 is controlled by 'GIGANTEA' and redundantly by ADO3, ADO2 and/or ADO1."}]}
+{"id": "function_test_308", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRWLWPLAVSLVVVLTVGLSGVSGAATSSLGGHRAKVQEQQSRPRRGTKDEGPKEVQHYVPEEWAEYPKPIHPAGLQPTKTLEATSPNPDKDGATPGNGQELRVNLTGTPSQRLQIQNPLYPVTESSYSAYAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAVIWVGSMMLAVPELLLWQLAQEPAPTAGTVDSCIMKPSADLPESVYSLVMTYQNARMWWYFGCYFCLPILFTVTCQLVTWRVRGPPGRKPECRAGRHEQCESQLNSTVVGLTVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLINQFSTFFKGAITPVLLLCICRPLGQAFLDCCCCCCCEECGGASDSSATVSADSKLKAEVSSSIYFHKPRESPPLLPLGTPC", "output": "G-protein coupled receptor . Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade (By similarity). However, other studies have shown that prosaposin does not increase activity (By similarity). It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha (By similarity). Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway . Regulates baseline blood pressure in females and protects against cardiovascular stress in males . Mediates inhibition of astrocyte glutamate transporters and reduction in neuronal N-methyl-D-aspartate receptor activity ."}]}
+{"id": "function_test_309", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPGKARKKSSCQLL", "output": "GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function (By similarity)."}]}
+{"id": "function_test_310", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEKRGVIDTWIDKHRSIYTAATRHAFVVSIRDGSVDLSSFRTWLGQDYLFVRRFVPFVASVLIRACKDSGESSDMEVVLGGIASLNDEIEWFKREGSKWDVDFSTVVPQRANQEYGRFLEDLMSSEVKYPVIMTAFWAIEAVYQESFAHCLEDGNKTPVELTGACHRWGNDGFKQYCSSVKNIAERCLENASGEVLGEAEDVLVRVLELEVAFWEMSRGGQ", "output": "Involved in thiamine salvage by hydrolyzing the thiamine breakdown product 4-amino-5-aminomethyl-2-methylpyrimidine (amino-HMP) to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP) . Has a high formylamino-HMP amidohydrolase activity . No activity with other thiamine degradation products such as thiamine mono- or diphosphate, oxothiamine, oxythiamine, thiamine disulfide, desthiothiamine or thiochrome as substrates . Does not display thiaminase II activity, as it is unable to hydrolyze thiamine . Is able to carry out two successive steps in the salvage of thiamine breakdown product, whereas two separate enzymes are required in Bacillus species (Probable). May also serve a damage pre-emption function by hydrolyzing products that would otherwise do harm (Probable)."}]}
+{"id": "function_test_311", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDLESESSVLESVEDNNGLIGDLDKELNSPVETSPLISKGFGLRKWKRRLRRDLVKDDTSVSMENSKALKRVLSGLVDPNAKQMHLPGPEVRQDSVGSVGSVNSVVGFVMGGESYGNGLAFAAGVDSDNSEDRSSTMSHSWDKHRGKVSGGKSVISSGDSSQQRKSSVEKSNKLRGERIKIEKENSHSSMESADSRSSNFVFMQGASYSLSSREQGGRRMMDYDDENSDHDAHTSKRKDNVEEEEEETEDYSQGDCVEESQIKSNGSSDNLDPLIVAVNSFQTLQEALQKELQKFQELGKEEPITSLHDGGESSSCIHAGHEGASEASSSYRFGSEKMGEMELTSLDSEILNLVNNVEHLEIKLEEAKRILEVKETQIRELESTINVSETCNGGTEIGIEDIFQQKVEAEIEYIIFSRSVGNLKRRIKLIEEEKTLGLSKLDKAETKAENLKNQAQDLQNHCVEITEIQEVECLKKRAFKTTRCLLLQLGLLFILYYSLLPEPEIAVPT", "output": "Mediates and enhances the nuclear envelope docking of RANGAP proteins mediated by WIT1 and WIT2 in the undifferentiated cells of root tips . As component of the SUN-WIP-WIT2-KAKU1 complex, mediates the transfer of cytoplasmic forces to the nuclear envelope (NE), leading to nuclear shape changes ."}]}
+{"id": "function_test_312", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRRSFSVLGPYKWLKPSSTYTNVYCFVTNPPLISNPNNGSAIFRYLSYFAPQQRRQQQQAPDPDDPANLLKEDGVSLCSQMWLENFKEPDKTATNLTSYLRRFELWVLAYQKVCCDELGAYVPRSSIQRSALENLLALRNSVLDDRFKWGSRLDFYIKSPRDKTDYESLSKRKIKAILTTTQPTPFQDRIVQEVLLMILEPIYESRFSQKSFAFRPGRTAHTVLRVIRRNFAGYLWYVKGDLSVVLDGMKVGFVISSLMRDVRDKKVIDLIKSALVTPVVTSKVEDGEKKKTKKRKYQKKRVLAEDEPKPDPYWLETFFGFAPEEAGKSPQWGHCGILSPLLVNVCLDELDRWMETKVKDFYRPSKSDVIWNNPEGEADQGNTSWPEFVPTSGPDKTRKMDYVRYGGHILIGVRGPRADAATLRKELIEFVDQKYMLRLDNENLPIEHITKGIMFLDHVLCRRVVYPTLRYTATGGKIISEKGVGTLLSVTASLKQCIKQFRKLLFIKGDRDPDPQPCFRMFHATQAHTNNQMNKFLTTIAEWYRFADNRKKIVNFCSYIIRGSLAKLYAAKYKLRSRAKVYKFANRNLSLPLLQKKGQSPEYQNLLRMGLAESVDGLVYTRMSLVPETDYSPFPGNWRPEHEKFLIEYLTLDEPKTLEEQKRFIREKGLVSPQDYTSMLVWNYKRNAIPMDQVSILKDQPFLLGSSSTYNRDNDDQKNKEEDEDSEDGLRIARM", "output": "Nuclear-encoded maturase required for splicing of group-II introns in mitochondria. Involved in the splicing of mitochondrial COX2, NAD1 and NAD7 transcripts . Necessary for mitochondrial biogenesis during early developmental stages ."}]}
+{"id": "function_test_313", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSFVVGVGGSGSGSGGDGGGSHHHDGSETDRKKKRYHRHTAQQIQRLESSFKECPHPDEKQRNQLSRELGLAPRQIKFWFQNRRTQLKAQHERADNSALKAENDKIRCENIAIREALKHAICPNCGGPPVSEDPYFDEQKLRIENAHLREELERMSTIASKYMGRPISQLSTLHPMHISPLDLSMTSLTGCGPFGHGPSLDFDLLPGSSMAVGPNNNLQSQPNLAISDMDKPIMTGIALTAMEELLRLLQTNEPLWTRTDGCRDILNLGSYENVFPRSSNRGKNQNFRVEASRSSGIVFMNAMALVDMFMDCVKWTELFPSIIAASKTLAVISSGMGGTHEGALHLLYEEMEVLSPLVATREFCELRYCQQTEQGSWIVVNVSYDLPQFVSHSQSYRFPSGCLIQDMPNGYSKVTWVEHIETEEKELVHELYREIIHRGIAFGADRWVTTLQRMCERFASLSVPASSSRDLGGVILSPEGKRSMMRLAQRMISNYCLSVSRSNNTRSTVVSELNEVGIRVTAHKSPEPNGTVLCAATTFWLPNSPQNVFNFLKDERTRPQWDVLSNGNAVQEVAHISNGSHPGNCISVLRGSNATHSNNMLILQESSTDSSGAFVVYSPVDLAALNIAMSGEDPSYIPLLSSGFTISPDGNGSNSEQGGASTSSGRASASGSLITVGFQIMVSNLPTAKLNMESVETVNNLIGTTVHQIKTALSGPTASTTA", "output": "Transcription factor which acts as positive regulator of drought stress tolerance. Can transactivate CIPK3, NCED3 and ERECTA . Transactivates several cell-wall-loosening protein genes by directly binding to HD motifs in their promoters. These target genes play important roles in coordinating cell-wall extensibility with root development and growth . Transactivates CYP74A/AOS, AOC3, OPR3 and 4CLL5/OPCL1 genes by directly binding to HD motifs in their promoters. These target genes are involved in jasmonate (JA) biosynthesis, and JA signaling affects root architecture by activating auxin signaling, which promotes lateral root formation . Acts as negative regulator of trichome branching . Required for the establishment of giant cell identity on the abaxial side of sepals . Seems to promote cell differentiation . May regulate cell differentiation and proliferation during root and shoot meristem development ."}]}
+{"id": "function_test_314", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSQLLSTPLMAVNSNPRFLSSSSVLVTGGFAVKRHGFALKPTTKTVKLFSVKSRQTDYFEKQRFGDSSSSPSPAEGLPARFYVGHSIYKGKAALTVDPRAPEFVALDSGAFKLSKDGFLLLQFAPSAGVRQYDWSKKQVFSLSVTEIGTLVSLGPRESCEFFHDPFKGKSDEGKVRKVLKVEPLPDGSGHFFNLSVQNKLVNVDESIYIPITRAEFAVLISAFNFVLPYLIGWHAFANSIKPEETSRVNNASPNYGGDYEWNR", "output": "Single-stranded DNA-binding protein that functions in both chloroplasts and nucleus. In chloroplasts, maintains plastid genome stability by preventing break-induced and short homology-dependent illegitimate recombinations. In nucleus, modulates telomere length homeostasis by inhibiting the action of the telomerase at the extreme termini of chromosomes. Is recruited to a distal element upstream of the kinesin KP1 to mediate the transcriptional repression of KP1. Is required for full salicylic acid-dependent plant disease resistance responses. Can bind double-stranded DNA in vivo."}]}
+{"id": "function_test_315", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSTDKLLLPNGVKSDGVIRMTRADAAAAAASSSLGGGSQIFDELPKAAIVSVSRPDTTDFSPLLLSYTLELQYKQFKWTLQKKASQVLYLHFALKKRLIIEELHDKQEQVREWLHSLGIFDMQGSVVQDDEEPDDGALPLHYTEDSIKNRNVPSRAALPIIRPTIGRSETVVDRGRTAMQGYLSLFLGNLDIVNSKEVCKFLEVSRLSFAREYGSKMKEGYVTVKHLRDVPGSDGVRCCLPTHCLGFFGTSWTKVWAVLKPGFLALLEDPFSGKLLDIMVFDTLGLQGTKESSEQPRLAEQVKEHNPLRFGFKVTSGDRTVRLRTTSSRKVKEWVKAVDEAGCYSPHRFGSFAPPRGLTSDGSQAQWFVDGHTAFEAIAFAIQNATSEIFMTGWWLCPELYLKRPFEDHPSLRLDALLETKAKQGVKIYILLYKEVQIALKINSLYSKKRLQNIHKNVKVLRYPDHLSSGIYLWSHHEKIVIVDYQVCFIGGLDLCFGRYDTAEHKIGDCPPYIWPGKDYYNPRESEPNSWEETMKDELDRRKYPRMPWHDVHCALWGPPCRDVARHFVQRWNHSKRNKAPNEQTIPLLMPHHHMVLPHYLGTREIDIIAAAKPEEDPDKPVVLARHDSFSSASPPQEIPLLLPQETDADFAGRGDLKLDSGARQDPGETSEESDLDEAVNDWWWQIGKQSDCRCQIIRSVSQWSAGTSQPEDSIHRAYCSLIQNAEHFIYIENQFFISGLEKEDTILNRVLEALYRRILKAHEENKCFRVVIVIPLLPGFQGGIDDFGAATVRALMHWQYRTISREGTSILDNLNALLGPKTQDYISFYGLRSYGRLFEDGPIATSQIYVHSKLMIVDDRIAVIGSSNINDRSLLGSRDSEIGVVIEDKEFVESSMNGMKWMAGKFSYSLRCSLWSEHLGLHAGEIQKIEDPIKDATYKDLWMATAKKNTDIYNQVFSCIPNEHIRSRAALRHNMALCKDKLGHTTIDLGIAPERLESCGSDSWEILKETRGNLVCFPLQFMCDQEDLRPGFNESEFYTAPQVFH", "output": "Hydrolyzes glycerol-phospholipids at the terminal phosphodiesteric bond to generate phosphatidic acids (PA). Phosphatidylcholine-selective . Regulates vesicle trafficking and auxin responses . Required for the normal cycling of PIN-2 containing vesicles . Contributes to the supply of inorganic phosphorus for cell metabolism and diacylglycerol moieties for galactolipid synthesis in phosphorus-starved roots . Involved in root elongation during phosphate limitation ."}]}
+{"id": "function_test_316", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGRPPCCDKIGVKKGPWTPEEDIILVSYIQEHGPGNWRSVPTHTGLRRCSKSCRLRWTNYLRPGIKRGNFTEHEEKMILHLQALLGNRWAAIASYLPERTDNDIKNYWNTHLKKKLKKMNDSCDSTINNGLDNKDFSISNKNTTSHQSSNSSKGQWERRLQTDINMAKQALCDALSIDKPQNPTNFSIPDLGYGPSSSSSSTTTTTTTTRNTNPYPSGVYASSAENIARLLQNFMKDTPKTSVPLPVAATEMAITTAASSPSTTEGDGEGIDHSLFSFNSIDEAEEKPKLIDHDINGLITQGSLSLFEKWLFDEQSHDMIINNMSLEGQEVLF", "output": "Transcription activator involved in the activation of cuticular wax biosynthesis under drought stress. Binds directly to the promoters of genes involved in cuticular wax biosynthesis. Transactivates WSD1, KCS2/DAISY, CER1, CER2, FAR3 and ECR genes . Functions together with MYB96 in the activation of cuticular wax biosynthesis ."}]}
+{"id": "function_test_317", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDICRLCLRGVSGAQMCLQIFDVDSGESKVAEVLRQHFWFEVLPNDEISKVICNVCWTQVSEFHQFYVSIQEAQVIYATTSKFKQDPEMVNTSWPEEVLMPADVLAVDNDVGAQINVNPLDELDLSQPMSPEDSKVGIKTERQSPDMELLFEDANNEQDEDYEDDEDDDTDDLIVTRSGRKRKRDVAKPAKTKRGTVSVGRKGKEKMVVKRGPPKRIFKMERLPPFCKEDEELIKRYIVMGCELCIFLAEDFDGIREHFKDKHPDERPYIKCCGRKLNKRCLIQEHARRHENPEYIKCKDCGKVFANSSVLRAHWLVHHVPDEECDFQCEDCGKRFSRRNLLELHKGSHVPVNERKFICPQCPKHNAFATEYHMQVHISMQHRKAANICHVCGKKIKDKAVFEKHVRLHFEESGPRIKCPRPDCESWLKDEDNLKQHLRRHNDEGKLFICSECGKSCKNSRALIGHKRYSHSNVIYTCEQCGKTFKKDISLKEHMAQHTGEPLYKCPFCPRTFNSNANMHSHKKKMHPVEWDIWRKTKTGSSQKVLPSAQVAQMFRDDADVAAIANDYSG", "output": "Transcription factor essential for the completion of meiosis in oocytes. Grauzone binds to the promoter region of cort via the zf-AD domain and activates cort expression in ovaries."}]}
+{"id": "function_test_318", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MVPIGAVHGGHPGVVHPPQQPLPTAPSGPNSLQPNSVGQPGATTSSNSSASNKSSLSVKPNYTLKFTLAGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQSKEVVQKLQGHTDTVLCTACHPTENIIASAALENDKTIKLWKSDT", "output": "Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4' . In neurons and together with DNA N6-methyl adenine demethylase Tet, plays a role in the maintenance of transcriptional activation for specific sets of genes ."}]}
+{"id": "function_test_319", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAAGQWVGVVERVLRGMVLKWGANLAVLGLCVFLFASATHANSLNAIEEPVTRRHHQRHHEREREENGYCAPYSGKVCKEYLTGQVWYSLEDPTGGWKNEQVTTALWDELISDLTGLCREAAEKMLCAYAFPNCHMEGGRAVKAPLCFEDCQATHLQFCYNDWVLIEEKKERNMFIKSRGHFRLPNCSSLPHYNASMRRPNCSYIGLTELKESEVSYDCRNGNGRFYMGTMNVSKSGIPCQRWDTQYPHKHFQPPLVFHQLLEGENYCRNAGGEEPHPWCYTVDESVRWQHCDIPMCPDYVDPNAVDLNTPIKMEKFFTPSMIFLLAGIGFVAIVTLHLMILLVYKLSKHKDYSQPAGAATAECSVSMRGGGDCGGNLNTSRETLGGNGNTNTLAKWGTIRSTATIHSNCVALTTVTNVSDAKGTKPNARLEKLEYPRGDIVYVRSLGQGAFGRVFQARAPGLVPDQEDLLVAVKMLKDDASDQMQMDFEREACLLAEFDHPNIVRLLGVCALGRPMCLLFEYMAPGDLSEFLRACSPYATHQAPTQDRLQLNELHLLQMAANIAAGMLYLSERKFVHRDLATRNCLINEHMAVKIADFGLSHKIYLQDYYKGDENDFIPIRWMPLESILYNKFSLESDVWAYGICLWEVFSFALQPYFGLTHEEVIKYIKEGNVLGCPDNTPLSVYALMRRCWNRKPSERPGFAEINHCIQHSIAESECKAML", "output": "Tyrosine-protein kinase receptor that functions during early stages of neuronal development."}]}
+{"id": "function_test_320", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAASGEQAPCSVYFCGSIRGGREDQALYARIVSRLRRYGKVLTEHVADAELEPLGEEAAGGDQFIHEQDLNWLQQADVVVAEVTQPSLGVGYELGRAVALGKPILCLFRPQSGRVLSAMIRGAADGSRFQVWDYAEGEVETMLDRYFEAYLPQKTASSSHPSA", "output": "Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases."}]}
+{"id": "function_test_321", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTVEYKRRPTFWEIFKARCSTADLGPISLNWFEELFSEAPPYNTEHPEESEYKPQGHEPQLFKTPQRNPSYHQFASTPIMFKEQSQTLPLDQSPFKELGNVVANSKRKHHSKKKARKDPVVDVASLPLKACPSESPCTPRCTQVAPQRRKPVVSGSLFYTPKLEETPKHISESLGVEVDPDMSWTSSLATPPTLSSTVLIARDEEAHRNAFPADSPASLKSYFSNHNESLKKNDRFIPSVSDSENKSQQEAFSQGLEKMLGDSSSKINRFRDCLRKPIPNVLEDGETAVDTSGEDSFSLCFPKRRTRNLQKTRMGKMKKKIFSETRTDGLSEEARGQADDKNSFALEIEPRDSEPLDPSVTNQKPLYSQSGDISSEAGQCSDSIWSQPDPSGLNGTQTRKIPLLHISFHKQSILEDFIDMKKEGTGSITFPHISSLPEPEKMFSEETLVDKEHEGQHLESLEDSISGKQMVSGTSQTACLSPSIRKSIVKMREPLEETLDTVFSDSMTSSAFTEELDASAGGLEIHTACSQREDSLCPSSVDTGSWPTTLTDTSATVKNAGLITTLKNKRRKFIYSVSDDASHQGKKLQTQRQSELTNLSAPFEASAFEVPFPFTNVDSGIPDSSIKRSNLPNDPEEPSLSLTNSFVTAASKEISYIHALISQDLNDKEAILSEEKPQPYTALEADFLSCLPERSCENDQKSPKVSDRKEKVLVSACRPSGRLAAAVQLSSISFDSQENPLGSHNVTSTLKLTPSPKTPLSKPVVVSRGKMCKMPEKLQCKSCKDNIELSKNIPLGVNEMCVLSENSETPELLPPLEYITEVSSSVKSQFNQNTKIAVVQKDQKDSTFISEVTVHMNSEELFPEKENNFAFQVTNESNKPNIGSTVEFQEEDLSHAKGHSLKNSPMTVDRDLDDEQAGQVLITEDSDSLAVVHDCTKKSRNTIEQHQKGTADKDFKSNSSLYLKSDGNNDYLDKWSEFLDPLMNHKLGGSFRTASNKEIKLSEDNVKKSKMFFKDIEEQYPTSLDCIDTVSTLQLANKKRLSEPHTFDLKSGTTVSTQCHSQSSVSHEDTHTAPQMLSSKQDFHSSHNLTPSQKAEITELSTILEESGSQFEFTQFKNPSHIAQNNTSAVLGNQMAVVRTASEEWKDVDLHLPLNPSSVGQIDHNKKFECLVGVKQSSSHLLEDTCNQNTSCFLPIKEMEFGGFCSALGTKLSVSNEALRKAMKLFSDIENISEEPSTKVGPRGFSSCAHHDSVASVFKIKKQNTDKSFDEKSSKCQVTVQNNKEMTTCILVDENPENYVKNIKQDNNYTGSQRNAYKLENSDVSKSSTSGTVYINKGDSDLPFAAEKGNKYPESCTQYVREENAQIKESVSDLTCLEVMKAEETCHMKSSDKEQLPSDKMEQNMKEFNISFQTASGKNIRVSKESLNKSVNILDQETEDLTVTSDSLNSKILCGINKDKMHISCHKKSINIKKVFEEHFPIGTVSQLPALQQYPEYEIESIKEPTLLSFHTASGKKVKIMQESLDKVKNLFDETQYVRKTTNFGHQESKPLKDREDYKERLTLAYEKIEVTASKCEEMQNFVSKQTEMLPQQNDHMYRQTENLTSNGSSPKVHGNIENKIEKNPRICCICQSSYFVTEDSALACYTGDSRKTCVGESSLSKGKKWLREQSDKLGTRNTIEIQCVKEHTEDFAGNALYEHSLVIIRTEIDTSHVSENQASTLFSDPNVCHSYLSHSSFCHHDDMHNDSGYFLKDKIDSDVQPDMKNTEGNAIFPKISATKEIKLHPQTVNEECVQKLETNASPYANKNIAIDSAMLDLRNCKVGSPVFITTHSQETVRMKEIFTDNCSKIVEQNRESKPDTCQTSCHKALDNSEDFICPSSSGDVCINSPMAIFYPQSEQILQHNQSVSGLKKAATPPVSLETWDTCKSIRGSPQEVHPSRTYGFFSTASGKAVQVSDASLEKARQVFSEIDGDAKQLASMVSLEGNEKSHHSVKRESSVVHNTHGVLSLRKTLPGNVSSFVFSGFSTAGGKLVTVSESALHKVKGMLEEFDLIRTEHTLQHSPTPEDVSKIPPQPCLESRTPEYSVSSKLQKTYNDKSRSPSNYKESGSSGNTQSLEVSPQLSQMERKQETQSVLGTKVSQRKTNILEKKQNLPQNIKIESNKMETFSDVSMKTNVGEYYSKEPENYFETEAVEIAKAFMEDDELTDSEQTHAKCSLFACPQNEALLNSRTRKRGGMAGVAVGQPPIKRSLLNEFDRIIESKGKSLTPSKSTPDGTIKDRRLFTHHMSLEPVTCGPFCSSKERQETQSPHVTSPAQGLQSKEHPSRHSAVGKSSSNPTVSALRSERTRHSVSDKSTKVFVPPFKVKSRFHRDEHFDSKNVNLEGKNQKSADGVSEDGNDSDFPQFNKDLMSSLQNARDLQDIRIKNKERHHLCPQPGSLYLTKSSTLPRISLQAAVGDSVPSACSPKQLYMYGVSKACISVNSKNAEYFQFAIEDHFGK", "output": "Involved in double-strand break repair and/or homologous recombination. Binds RAD51 and potentiates recombinational DNA repair by promoting assembly of RAD51 onto single-stranded DNA (ssDNA). Acts by targeting RAD51 to ssDNA over double-stranded DNA, enabling RAD51 to displace replication protein-A (RPA) from ssDNA and stabilizing RAD51-ssDNA filaments by blocking ATP hydrolysis. Part of a PALB2-scaffolded HR complex containing RAD51C and which is thought to play a role in DNA repair by HR. May participate in S phase checkpoint activation. Binds selectively to ssDNA, and to ssDNA in tailed duplexes and replication fork structures. May play a role in the extension step after strand invasion at replication-dependent DNA double-strand breaks; together with PALB2 is involved in both POLH localization at collapsed replication forks and DNA polymerization activity. In concert with NPM1, regulates centrosome duplication. Interacts with the TREX-2 complex (transcription and export complex 2) subunits PCID2 and SEM1, and is required to prevent R-loop-associated DNA damage and thus transcription-associated genomic instability, independently of its known role in homologous recombination (By similarity)."}]}
+{"id": "function_test_322", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSLHPASPRLASLLLFILALHDTLALRLCSFNVRSFGASKKENHEAMDIIVKIIKRCDLILLMEIKDSSNNICPMLMEKLNGNSRRSTTYNYVISSRLGRNTYKEQYAFVYKEKLVSVKTKYHYHDYQDGDTDVFSREPFVVWFHSPFTAVKDFVIVPLHTTPETSVKEIDELVDVYTDVRSQWKTENFIFMGDFNAGCSYVPKKAWQNIRLRTDPKFVWLIGDQEDTTVKKSTSCAYDRIVLCGQEIVNSVVPRSSGVFDFQKAYDLSEEEALDVSDHFPVEFKLQSSRAFTNNRKSVSLKKRKKGNRS", "output": "Has DNA hydrolytic activity. Is capable of both single- and double-stranded DNA cleavage, producing DNA fragments with 3'-OH ends (By similarity). Can cleave chromatin to nucleosomal units and cleaves nucleosomal and liposome-coated DNA . Acts in internucleosomal DNA fragmentation (INDF) during apoptosis and necrosis. The role in apoptosis includes myogenic and neuronal differentiation, and BCR-mediated clonal deletion of self-reactive B cells . Is active on chromatin in apoptotic cell-derived membrane-coated microparticles and thus suppresses anti-DNA autoimmunity . Together with DNASE1, plays a key role in degrading neutrophil extracellular traps (NETs) . NETs are mainly composed of DNA fibers and are released by neutrophils to bind pathogens during inflammation . Degradation of intravascular NETs by DNASE1 and DNASE1L3 is required to prevent formation of clots that obstruct blood vessels and cause organ damage following inflammation ."}]}
+{"id": "function_test_323", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAGPGAWKRLKSLLRKDDAPLFLNDTSAFDFLDEVSDEGLSRFNKLRVVVADDDSEAPERPVNGAHPALQADDDSLLDQELPLTNSQLSLKMDPCDNCSKRRELLKQRKVKTRLTIAAVLYLLFMIGELVGGYMANSLAIMTDALHMLTDLSAIILTLLALWLSSKSPTRRFTFGFHRLEVLSAMISVMLVYVLMGFLLYEAMQRTIHMNYEINGDVMLITAAVGVAVNVIMGFLLNQSGHHHSHAHSHSLPSNSPSMVSSGHSHGQDSLAVRAAFVHALGDLVQSVGVLIAAYIIRFKPEYKIADPICTYIFSLLVAFTTLRIIWDTVVIILEGVPSHLNVDYIKESLMKIEDVYSVEDLNIWSLTSGKATAIVHMQLIPGSSSKWEEVQSKAKHLLLNTFGMYKCTVQLQSYRQEATRTCANCQSSST", "output": "Probable proton-coupled zinc ion antiporter mediating zinc import from cytoplasm potentially into the endocytic compartment (By similarity). Controls zinc deposition in milk (By similarity)."}]}
+{"id": "function_test_324", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MARDGGVSCLRRSEMMSVGGIGGIESAPLDLDEVHVLAVDDSLVDRIVIERLLRITSCKVTAVDSGWRALEFLGLDNEKASAEFDRLKVDLIITDYCMPGMTGYELLKKIKESSNFREVPVVIMSSENVLTRIDRCLEEGAQDFLLKPVKLADVKRLRSHLTKDVKLSNGNKRKLPEDSSSVNSSLPPPSPPLTISPESSPPLTVSTESSDSSPPLSPVEIFSTSPLSSPIDDEDDDVLTSSSEESPIRRQKMRSPGLD", "output": "Functions as response regulator involved in His-to-Asp phosphorelay signal transduction system. Phosphorylation of the Asp residue in the receiver domain activates the ability of the protein to promote the transcription of target genes. Type-A response regulators seem to act as negative regulators of the cytokinin signaling. Modulates red light signaling through its interaction with the phytochrome B photoreceptor."}]}
+{"id": "function_test_325", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGLFDRGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRGVCKTKSVSENETSKKNEEVMTHSGLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGLCIAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGDPSKSDSKKNSYSYGWSFYFGALSFIIAEMVGVLAVHMFIDRHKQLRATARATDYLQASAITRIPSYRYRYQRRSRSSSRSTEPSHSRDASPVGVKGFNTLPSTEISMYTLSRDPLKAATTPTATYNSDRDNSFLQVHNCIQKDSKDSLHANTANRRTTPV", "output": "Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity)."}]}
+{"id": "function_test_326", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKLLAMVALLVTICSLEGALVKRQADGPDMQSLFTQYFQSMTDYGKDLMEKAKTSEIQSQAKAYFEKTHEQLTPLVRSAGTSLVNFFSSLMNLEEKPAPAAK", "output": "May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism."}]}
+{"id": "function_test_327", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKPVHERSQECLPPKKRDLPVTSEDMGRTTSCSTNHTPSSDASEWSRGVVVAGQSQTGARVSLGGDGTEAITGLTVDQYGMLYKVAVPPATFSPTGLPSVVNMSPLPPTFNVASSLIQHPGIHYPPVHYAQLPSTSLQFIGSPYSLPYAVPPNFLPSPLLSPSANLATTHLPHFVPYASLLAEEATPPPQAASPAQSFNKSSSATSPPGQLPHHSNTQPLDLAPGRMPIYYQMSRLPAGYTLHETSTAGASPILTPQEGQSALEAAAANGQRQRERNVRRESEALDSASSKGESQGLVPVVECMADGQLFSGSQTPRVEVAAPAHRGTPDTDLEVQRVVGALASQDYRVVAAQRKDEPSPLNLSHHNLDHQGEGRGSARNPTELVEKSQARVFYPQSHQEPVKHRPLPKAMVVANGNLVPTGTDPSLLPVGSEILVASSLDLQARATFPDKEPTPPPVTSSHLPSHFMKGAIIQLATGELKRVEDLQTQDFVRSAEVSGGLKIDSSTVVDIQESQWPGFVMLHFVVGEQQSKVSIEVPPEHPFFVYGQGWSSCSPGRTAQLFSLPCHRLQVGDVCISISLQSLNSNSVSQASCAPPGQLGTPRERPERTVLGPRDLCDSEGKNQPSGEGSRVGEPSQPEPGAQACWPAPSFQRFSMQGEEARAAMLRPSFIPQEVKLSIEGRSNAGK", "output": "Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression (By similarity). Can suppress the cytotoxicity of ATXN1 in spinocerebellar ataxia type 1 (SCA1) . In concert with CIC and ATXN1, involved in brain development ."}]}
+{"id": "function_test_328", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGMQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGC", "output": "[Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored) (By similarity). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains) . Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in proteotoxic stress response and cell cycle; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B (By similarity). Linear polymer chains formed via attachment by the initiator Met lead to cell signaling (By similarity). Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed (By similarity). When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling (By similarity)."}]}
+{"id": "function_test_329", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSEQNSVVNAEKGDGEISSNVETASSVNPSVKPQNAIKEEAKETNGEDQKCKGPENAGSTAETKETSNDATNGMKTPEETEDTNDKRHDDEGEDGDEDEDEDEDEDEDNGDEDDEDVDSSSSETSSEDGEDSESVSGESTESSSGEDEESDESDGNTSNSSSGDESGSEEEEEEEEEEEEEENAGEPAIAHQDSVPTNDSTAPRSTHTRNISLSSNGSNTNSTIILVKTTLETILNDKDIKKNSNAQKAIERTLQKFKEFDPQTTNNPHYVDSILVFEALRASCRTKSSKVQSLALDCLSKLFSFRSLDETLLVNPPDSLASNDQRQDAADGITPPPKQKIIDAAIDTISDCFQGEGTDDRVELQIVRALSSCILEEDSSSLCHGASLLKAIRTIYNVFVFSLNPSNQGIAQATLTQIISSVYDKIDLKQSTSSAVSLSTKNHQQQSAIELSEASENAETPAPLTLENMDKLNDDEERLMDAQQPDSIAITNQDLAVKDAFLVFRVMAKICAKPLETELDMRSHAVRSKLLSLHIIYSIIKDHIDVFLSHNIFLPGKERVCFIDSIRQYLRLVLSRNAASPLAPVFEVTLEIMWLLIANLRADFVKEIPVFLTEIYFPISELTTSTSQQKRYFLSVIQRICNDPRTLVEFYLNYDCNPGMPNVMEITVDYLTRLALTRVEITQTQRSYYDEQISKSLSTYNFSQLPLLTSSNLSSSPDVGQVNLLFPLDFALKMVSLNCIVSVLRSLSSWAHKALNPNTHTANKVLLNTTSSARQESRSSLSNDVRSSIMTSNDDFKPTYEDEESRSLSSQNIDADDPTQFENLKLRKTALSECIAIFNNKPKKAIPVLIKKGFLKDDSPISIAKWLLETEGLDMAAVGDYLGEGDDKNIAIMHAFVDEFDFTGMSIVDALRSFLQSFRLPGEGQKIDRFMLKFAERFVDQNPGVFSKADTAYVLSYSLIMLNTDLHSSQIKNKMSLQEFLENNEGIDNGRDLPRDFLEGLFNEIANNEIKLISEQHQAMLSGDTNLVQQQQSAFNFFNSRDLTREAYNQVSKEISSKTELVFKNLNKNKGGPDVYYAASHVEHVKSIFETLWMSFLAALTPPFKDYDDIDTTNKCLEGLKISIKIASTFRINDARTSFVGALVQFCNLQNLEEIKVKNVNAMVILLEVALSEGNYLEGSWKDILLVVSQMERLQLISKGIDRDTVPDVAQARVANPRVSYESSRSNNTSFFDVWGKKATPTELAQEKHHNQTLSPEISKFISSSELVVLMDNIFTKSSELSGNAIVDFIKALTAVSLEEIESSENASTPRMFSLQKMVDVCYYNMDRIKLEWTPLWAVMGKAFNKIATNSNLAVVFFAIDSLRQLSMRFLDIEELSGFEFQHDFLKPFEYTVQNSGNTEVQEMIIECFRNFILTKSESIKSGWKPILESLQYTARSSTESIVLKTQLLVSNDIVTNHFENVFSQEDAFSELVGVFREITKNKRFQKLSLHALESLRKMTQNVADICFYNENKTEEERKHNDALLRGKDIFQDVWFPMLFCFNDTIMTAEDLEVRSRALNYMFDALVAYGGKFNDDFWEKICKKLLFPIFGVLSKHWEVNQFNSHDDLSVWLSTTLIQALRNLIALFTHYFESLNRMLDGFLGLLVSCICQENDTIARIGRSCLQQLILQNVSKFNEYHWNQIGDVFDKLFDLTTANELFDYDPLQQGRKSSVSHHQTTNDTSQHSDDDSNDRRENDSNISETVERAHQEESSEDVGGDMVETLNGQTKLNNGNSVPTVKDELNPKPASLSIPKKTKHMKRNESNEDIRRRINIKNSIVVKCVLQLLMIELLNELFENEDFAHCIPYKEAIRITRLLEKSYEFSRDFNEDYGLRTRLVEARVVDKIPNLLKQETSAAAVLLDIMFQLYLNDDEKKADLITRLITICIQVVEGYVSLDDRTMERSINAWRSVIVEILQGYYEFDDEDFRLYCPAMYALVIQILDKSVPTELRHAIKQFLSRVGELYLSTD", "output": "May play a role in vesicular budding and traffic between compartments of the Golgi apparatus."}]}
+{"id": "function_test_330", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MASSTPSPATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEKSRLVSAFRERQASKNLLSCENSDPGARFRRTETDFSNLFAQDLLPAKNGEEQTVQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIIGWSNKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVPKLVLFTSEHSHYSIKKAGAALGFGTDNVILIKCNERGKIIPADLEAKILDAKQKGFVPLYVNATAGTTVYGAFDPIQEIADICEKYNLWLHVDAAWGGGLLMSRKHRHKLSGIERANSVTWNPHKMMGVLLQCSAILVKEKGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQINKCLELAEYLYAKIKNREEFEMVFNGEPEHTNVCFWYIPQSLRGVPDSPERREKLHRVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATQSDIDFLIEEIERLGQDL", "output": "Catalyzes the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) with pyridoxal 5'-phosphate as cofactor."}]}
+{"id": "function_test_331", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MFRQEQPLAEGSFAPMGSLQPDAGNSSWNGTEAPGGGTRATPYSLQVTLTLVCLAGLLMLFTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKVWCEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIVTVWVISAVISFPPLISIEKKGAGGGQQPAEPSCKINDQKWYVISSSIGSFFAPCLIMILVYVRIYQIAKRRTRVPPSRRGPDACSAPPGGADRRPNGLGPERGAGTAGAEAEPLPTQLNGAPGEPAPTRPRDGDALDLEESSSSEHAERPQGPGKPERGPRAKGKTKASQVKPGDSLPRRGPGAAGPGASGSGQGEERAGGAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLIAVGCPVPYQLFNFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV", "output": "Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins."}]}
+{"id": "function_test_332", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MARDLQNHLLFEVATEVTNRVGGIYSVLKSKAPVTVAQYGDNYTLLGPLNKATYESEVEKLDWEDESIFPEELLPIQKTLMSMREKGVNFVYGNWLIEGAPRVILFELDSVRHFLNEWKADLWSLVGIPSPEHDHETNDAILLGYVVVWFLGEVSKLDSSHAIIGHFHEWLAGVALPLCRKKRIDVVTIFTTHATLLGRYLCAAGDVDFYNNLQYFDVDQEAGKRGIYHRYCIERAAAHTADVFTTVSQITALEAEHLLKRKPDGILPNGLNVVKFQAVHEFQNLHALKKDKINDFVRGHFHGCFDFDLDNTVYFFIAGRYEYKNKGADMFIESLARLNYRLKVSGSKKTVVAFLIMPAKTNSFTVEALKSQAIVKSLENTVNEVTASIGKRIFEHTMRYPHNGLESELPTNLDELLKSSEKVLLKKRVLALRRPYGELPPVVTHNMCDDANDPILNQIRHVRLFNDSSDRVKVIFHPEFLNANNPILGLDYDEFVRGCHLGVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGAYMEDLIETDQAKDYGIYIVDRRFKSPDESVEQLADYMEEFVNKTRRQRINQRNRTERLSDLLDWKRMGLEYVKARQLGLRRAYPEQFKQLVGETISDANMNTLAGGKKFKIARPLSVPGSPKVRSNSTVYMTPGDLGTLQDANNADDYFNLSTNGAIDNDDDDNDTSAYYEDN", "output": "Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan. Is believed to regulate the synthesis of glycogen."}]}
+{"id": "function_test_333", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNSFASLGLIYSVVNLLTRVEAQIVFYQNSSTSLPVPTLVSTSIADFHESSSTGEVQYSSSYSYVQPSIDSFTSSSFLTSFEAPTETSSSYAVSSSLITSDTFSSYSDIFDEETSSLISTSAASSEKASSTLSSTAQPHRTSHSSSSFELPVTAPSSSSLPSSTSLTFTSVNPSQSWTSFNSEKSSALSSTIDFTSSEISGSTSPKSLESFDTTGTITSSYSPSPSSKNSNQTSLLSPLEPLSSSSGDLILSSTIQATTNDQTSKTIPTLVDATSSLPPTLRSSSMAPTSGSDSISHNFTSPPSKTSGNYDVLTSNSIDPSLFTTTSEYSSTQLSSLNRASKSETVNFTASIASTPFGTDSATSLIDPISSVGSTASSFVGISTANFSTQGNSNYVPESTASGSSQYQDWSSSSLPLSQTTWVVINTTNTQGSVTSTTSPAYVSTATKTVDGVITEYVTWCPLTQTKSQAIGVSSSISSVPQASSFSGSSILSSNSSTLAASNNVPESTASGSSQYQDWSSSSLPLSQTTWVVINTTNTQGSVTSTTSPAYVSTATKTVDGVITEYVTWCPLTQTKSQAIGISSSTISATQTSKPSSILTLGISTLQLSDATFKGTETINTHLMTESTSITEPTYFSGTSDSFYLCTSEVNLASSLSSYPNFSSSEGSTATITNSTVTFGSTSKYPSTSVSNPTEASQHVSSSVNSLTDFTSNSTETIAVISNIHKTSSNKDYSLTTTQLKTSGMQTLVLSTVTTTVNGAATEYTTWCPASSIAYTTSISYKTLVLTTEVCSHSECTPTVITSVTATSSTIPLLSTSSSTVLSSTVSEGAKNPAASEVTINTQVSATSEATSTSTQVSATSATATASESSTTSQVSTASETISTLGTQNFTTTGSLLFPALSTEMINTTVVSRKTLIISTEVCSHSKCVPTVITEVVTSKGTPSNGHSSQTLQTEAVEVTLSSHQTVTMSTEVCSNSICTPTVITSVQMRSTPFPYLTSSTSSSSLASTKKSSLEASSEMSTFSVSTQSLPLAFTSSEKRSTTSVSQWSNTVLTNTIMSSSSNVISTNEKPSSTTSPYNFSSGYSLPSSSTPSQYSLSTATTTINGIKTVYTTWCPLAEKSTVAASSQSSRSVDRFVSSSKPSSSLSQTSIQYTLSTATTTISGLKTVYTTWCPLTSKSTLGATTQTSSTAKVRITSASSATSTSISLSTSTESESSSGYLSKGVCSGTECTQDVPTQSSSPASTLAYSPSVSTSSSSSFSTTTASTLTSTHTSVPLLPSSSSISASSPSSTSLLSTSLPSPAFTSSTLPTATAVSSSTFIASSLPLSSKSSLSLSPVSSSILMSQFSSSSSSSSSLASLPSLSISPTVDTVSVLQPTTSIATLTCTDSQCQQEVSTICNGSNCDDVTSTATTPPSTVTDTMTCTGSECQKTTSSSCDGYSCKVSETYKSSATISACSGEGCQASATSELNSQYVTMTSVITPSAITTTSVEVHSTESTISITTVKPVTYTSSDTNGELITITSSSQTVIPSVTTIITRTKVAITSAPKPTTTTYVEQRLSSSGIATSFVAAASSTWITTPIVSTYAGSASKFLCSKFFMIMVMVINFI", "output": "Required for efficient mating. Plays a role in maintenance of cell wall integrity during mating. Important for mating cell projection shape and conjugation bridge diameter. Plays a role in cell fusion and nuclear migration."}]}
+{"id": "function_test_334", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGKKTFREWQYFKLSITSFDQDVDDAHAIDQMTWRQWLNNALKRSYGIFGEGVEYSFLHVDDKLAYIRVNHADKDTFSSSISTYISTDELVGSPLTVSILQESSSLRLLEVTDDDRLWLKKVMEEEEQDCKCI", "output": "Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP, which cleaves pre-rRNA sequences."}]}
+{"id": "function_test_335", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKTEGIKSPSAKYHDMAGSQRIPHKNPHIQKVAVLQSKPNKEDALNLIKEIAHKVSYLMKENHFKVTNLVEFYPRDQRLLGMNVNHGSKIMLRLRCSTDEFQFLPMECIMGTMLHELTHNLFGPHDKKFYNKLDELIGRQWVIEQRGLYDTFLGNGQRLGGRANLRSNRYPMTGISTNTGIVRKRGKGVKLGSLHPEGISSIDRGNSPRELAAFAAERRYRDDRWCGETKNNKDQIISDNISSSLEVVILDDDDEVLPGDTLIEVIDLT", "output": "Metalloendopeptidase that acts selectively on DNA-binding proteins. DNA is needed to bring the protease and substrates together to enable proteolysis. Involved in the repair of toxic DNA-protein cross-links (DPCs) such as covalently trapped topoisomerase 1 (TOP1) adducts on DNA lesions or DPCs induced by reactive compounds such as formaldehyde. Involved in DNA damage response and processing of stalled or collapsed replication forks by removing the covalently trapped TOP1 from chromatin. DPC proteolysis enables the repair of the lesions via downstream DNA repair pathways. May be recruited to DPCs via the SUMOylation of substrate proteins at damaged DNA sites."}]}
+{"id": "function_test_336", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEHHKTYHSANIKTATGSLLIEGPVSPEDLAGYEFHKDLTAFRPPREQHEALVDIAGLPEGRIIIARDGRTIVGYVTYLYPDPLERWSEGNMEDLIELGAIEVAPDYRGCAVGKTLLTVSMMDEQMENYIVMTTEYYWHWDLKGMKKDVWEYRKIMEKMMNAGGLVWFATDEPEISSHPANCLMARIGKNVSQESIEQFDRLRFYHRYMY", "output": "Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue."}]}
+{"id": "function_test_337", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSAAPLDYKKALEHLKTYSSKDGLSVQELMDSTTRGGLTYNDFLVLPGLVNFPSSAVSLQTKLTKKITLNTPFVSSPMDTVTEADMAIYMALLGGIGFIHHNCTPKEQASMVKKVKMFENGFINSPIVISPTTTVGEVKVMKRKFGFSGFPVTEDGKCPGKLVGLVTSRDIQFLEDDSLVVSEVMTKNPVTGIKGITLKEGNEILKQTKKGKLLIVDDNGNLVSMLSRADLMKNQNYPLASKSATTKQLLCGAAIGTIEADKERLRLLVEAGLDVVILDSSQGNSVFQLNMIKWIKETFPDLEIIAGNVATREQAANLIAAGADGLRIGMGSGSICITQEVMACGRPQGTAVYNVCQFANQFGVPCMADGGVQNIGHITKALALGSSTVMMGGMLAGTTESPGEYFYKDGKRLKAYRGMGSIDAMQKTGNKGNASTSRYFSESDSVLVAQGVSGAVVDKGSIKKFIPYLYNGLQHSCQDIGCESLTSLKENVQNGEVRFEFRTASAQLEGGVHNLHSYEKRLYN", "output": "Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth."}]}
+{"id": "function_test_338", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSEKVNSDFEDFSSDEETDQHNVLIQTKKKISSKDDIFSKKVEDIESENESDIEEEQKQEEKEDVEQPDKENGEKLDREVEEQASSTTSLDLKTEKLRQLVKSKAAKKSKHKTGVVYFSSIPPYMKPAKMRQILTRFGEVDRLFLKKEDDQKYKQRVKGGGNKKNKYEEGWAEFIRKRDAKLCAETLNGNIIGGKKGTFYHDDILNVKYLPGFKWADLTEQIARENDIRQAKLEMEISQANKLNAEFIRNVEQSKMIQNIKNSRKRAGKEGESADSHPHREFKQRRVETSRANAPSDIKQQSSGSKDLGNVLTNLL", "output": "Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2. Stimulates DBP8 RNA helicase ATPase activity."}]}
+{"id": "function_test_339", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAPKQDPKPKFQEGERVLCFHGPLLYEAKCVKVAIKDKQVKYFIHYSGWNKKSAVRPRRSEKSLKTREDIVALFPVPEGAPSVHHPLLTSSWDEWVPESRVLKYVDTNLQKQRELQKANQEQYAEGKMRGAAPGKKTSGLQQKNVEVKTKKNKQKTPGNGDGGSTSETPQPPRKKRARVDPTVENEETFMNRVEVKVKIPEELKPWLVDDWDLITRQKQLFYLPAKKNVDSILEDYANYKKSRGNTDNKEYAVNEVVAGIKEYFNVMLGTQLLYKFERPQYAEILADHPDAPMSQVYGAPHLLRLFVRIGAMLAYTPLDEKSLALLLNYLHDFLKYLAKNSATLFSASDYEVAPPEYHRKAV", "output": "Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also a component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci (By similarity)."}]}
+{"id": "function_test_340", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGRVIRGQRKGAGSVFRAHVKHRKGAARLRAVDFAERHGYIKGIVKDIIHDPGRGAPLAKVVFRDPYRFKKRTELFIAAEGIHTGQFVYCGKKAQLNIGNVLPVGTMPEGTIVCCLEEKPGDRGKLARASGNYATVISHNPETKKTRVKLPSGSKKVISSANRAVVGVVAGGGRIDKPILKAGRAYHKYKAKRNCWPRVRGVAMNPVEHPFGGGNHQHIGKPSTIRRDAPAGRKVGLIAARRTGRLRGTKTVQEKEN", "output": "Component of the large ribosomal subunit . The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell ."}]}
+{"id": "function_test_341", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSTDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGVERDAVFGFLSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSARTTSMLVIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVPLSIIVLTLLFMIQKHGTAMVGKLFAPIMLTWFLILAGLGLRSIIANPEVLHALNPMWAVHFFLEYKTVSFIALGAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLTLNYFGQGALLLKNPEAIKNPFFLLAPDWALIPLLIIAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMESGQIYIPFVNWMLYVAVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARQNWHWNKYFVALILIAFLCVDIPLFTANLDKLLSGGWLPLSLGTVMFIVMTTWKSERFRLLRRMHEHGNSLEAMIASLEKSPPVRVPGTAVYMSRAINVIPFALMHNLKHNKVLHERVILLTLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETPNVEEVFHRCGLEGLSCRMMETSFFMSHESLILGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI", "output": "Responsible for the low-affinity transport of potassium into the cell . Likely operates as a K(+):H(+) symporter . Kup is probably the major potassium uptake system upon hyper-osmotic stress at a low pH . Can also transport Cs(+) and Rb(+) . In the absence of potassium, Kup-mediated Cs(+) uptake partially supports cell growth, however, at a much lower rate than with sufficient K(+) . This effect depends on the maintenance of basal levels of intracellular K(+) by other K(+) uptake transporters ."}]}
+{"id": "function_test_342", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLDRISVYYNEATGGKYVPRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQVFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMAVTFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEEDFGEEAEEEA", "output": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin."}]}
+{"id": "function_test_343", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAECCVPVCQRPICIPPPYADLGKAARDIFNKGFGFGLVKLDVKTKSCSGVEFSTSGSSNTDTGKVSGTLETKYKWCEYGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSAYKRECINLGCDVDFDFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRSNFAVGYRTGDFQLHTNVNNGTEFGGSIYQKVCEDFDTSVNLAWTSGTNCTRFGIAAKYQLDPTASISAKVNNSSLIGVGYTQTLRPGVKLTLSALVDGKSFNAGGHKLGLALELEA", "output": "Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules (By similarity). The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV (By similarity). The open state has a weak anion selectivity whereas the closed state is cation-selective (By similarity). Binds various lipids, including the sphingolipid ceramide, the phospholipid phosphatidylcholine, and the sterol cholesterol (By similarity). Binding of ceramide promotes the Binding of ceramide promotes the mitochondrial outer membrane permeabilization (MOMP) apoptotic pathway (By similarity)."}]}
+{"id": "function_test_344", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTATIDVDNLMSRLLNVGMSGGRLTTSVNEQELQTCCAVAKSVFASQASLLEVEPPIIVCGDIHGQYSDLLRIFDKNGFPPDINFLFLGDYVDRGRQNIETICLMFCFKIKYPENFFMLRGNHECPAINRVYGFYEECNRRYKSTRLWSIFQDTFNWMPLCGLIGSRILCMHGGLSPHLQTLDQLRQLPRPQDPPNPSIGIDLLWADPDQWVKGWQANTRGVSYVFGQDVVADVCSRLDIDLVARAHQVVQDGYEFFASKKMVTIFSAPHYCGQFDNSAATMKVDENMVCTFVMYKPTPKSLRKG", "output": "Probable phosphatase which plays a redundant role with gsp-4 in spermatogenesis by regulating sister chromatid segregation during meiosis . In addition, involved in sperm motility by controlling the dynamic disassembly of major sperm proteins (MSP) in the spermatozoan pseudopodium ."}]}
+{"id": "function_test_345", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPPKGWRKDAQGNYPTTSYIKEQENITIQDLLFPKSTIVNLAREVPQQSGKKLLINKDASLALQRGATVFVNHLLLFAREIAKSQDKKSCSVDDVLSALDHIGHSALKGPVRDKLDEYQAAVEQRKKEKLDSGEVDADGDIDMGEDKENVPVEKVKEHDEIEEQGDALQDVEESSEKKQKTESQDVETRVQNLEQT", "output": "As accessory component of the DNA polymerase epsilon (DNA polymerase II) participates in chromosomal DNA replication. It is required during synthesis of the leading and lagging DNA strands at the replication fork and binds at/or near replication origins and moves along DNA with the replication fork. It has 3'-5' proofreading exonuclease activity that correct errors arising during DNA replication. It is also involved in DNA synthesis during DNA repair. Also functions as component of the ISW2 complex, which acts in remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. The ISW2 complex is involved in coordinating transcriptional repression and in inheritance of telomeric silencing. It is involved in repression of MAT a-specific genes, INO1, and early meiotic genes during mitotic growth dependent upon transcription factor UME6 and in a parallel pathway to the RPD3-SIN3 histone deacetylase complex."}]}
+{"id": "function_test_346", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSNESTNCSFFLNLFMLLLLLIFYSADACQRECGGISIPYPFGIGKDCCLEKYYEIECRNTTSRKLVPLLSFINKEVVSISLPSADSHFAYEVSDQERHESFGLVRVKFPITSAGCFNDGKESGGGSKMNFTGSPFFIDRSNSLIAAGCNSKVSLMYIKPKMVGCELSCNTSKDSYSNSIPFVEAGCSSNVLPYSQDQGCPEEIAEETGCNGIGCCQASLPNEPQQVIGIRTENNDGNSTTKVECTVSAFLTDEIYALPKATKTEHLLAKRYATVSLGWVIQTSNRSFLDSLALACKDREDYRNTTNLERKCTCGRITISETSYANCGCTYGYTGNPYVLNGCKDIDECKVKFEYCGKTETCVNFEGGYRCVRDKTKAIMIGAGTGFGVLVLVGGLWWLRKFLIKRRITKRKKKFFKRNGGLLLLQELNTREGYVEKTRVFNSRELEKATENFSENRVLGHGGQGTVYKGMLVDGRTVAVKKSKVIDEDKLQEFINEVVILSQINHRHVVKLLGCCLETEVPMLVYEFIINGNLFKHIHEEESDDYTMLWGMRLRIAVDIAGALSYLHSSASSPIYHRDIKSTNILLDEKYRAKVADFGTSRSVTIDQTHWTTVISGTVGYVDPEYYQSSQYTEKSDVYSFGVILAELITGDKPVIMVQNTQEIVALAEHFRVAMKEKRLTDIIDARIRNDCKPEQVMAVAKVAMKCLSSKGKKRPNMREVFTELERICTSPEDSQVHNRIDEEEEEEEEEEEVVTTINRGDSWSISVTAPALSIVASSPSSDVEPLFPRLTW", "output": "Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component."}]}
+{"id": "function_test_347", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLGWVQRVLPQPPGTPQKTKQEEEGTEPEPELEPKPETAPEETELEEVSLPPEEPCVGKEVAAVTLGPQGTQETALTPPTSLQAQVSVAPEAHSSPRGWVLTWLRKGVEKVVPQPAHSSRPSQNIAAGLESPDQQAGAQILGQCGTGGSDEPSEPSRAEDPGPGPWLLRWFEQNLEKMLPQPPKISEGWRDEPTDAALGPEPPGPALEIKPMLQAQESPSLPAPGPPEPEEEPIPEPQPTIQASSLPPPQDSARLMAWILHRLEMALPQPVIRGKGGEQESDAPVTCDVQTISILPGEQEESHLILEEVDPHWEEDEHQEGSTSTSPRTSEAAPADEEKGKVVEQTPRELPRIQEEKEDEEEEKEDGEEEEEEGREKEEEEGEEKEEEEGREKEEEEGEKKEEEGREKEEEEGGEKEDEEGREKEEEEGRGKEEEEGGEKEEEEGRGKEEVEGREEEEDEEEEQDHSVLLDSYLVPQSEEDRSEESETQDQSEVGGAQAQGEVGGAQALSEESETQDQSEVGGAQDQSEVGGAQAQGEVGGAQEQDGVGGAQDQSTSHQELQEEALADSSGVPATEEHPELQVEDADADSRPLIAEENPPSPVQLPLSPAKSDTLAVPGSATGSLRKRLPSQDDEAEELKMLSPAASPVVAWSDPTSPQGTDDQDRATSTASQNSAIINDRLQELVKLFKERTEKVKEKLIDPDVTSDEESPKPSPAKKAPEPAPEVKPAEAGQVEEEHYCEMLCCKFKRRPWKKYQFPQSIDPLTNLMYILWLFFVVLAWNWNCWLIPVRWAFPYQTPDNIHLWLLMDYLCDLIYLLDITVFQMRLQFVRGGDIITDKKEMRNNYVKSQRFKMDMLCLLPLDLLYLKFGVNPLLRLPRCLKYMAFFEFNNRLESILSKAYVYRVIRTTAYLLYSLHLNSCLYYWASAYEGLGSTHWVYDGVGNSYIRCYYWAVKTLITIGGLPDPRTLFEIVFQGLNYFTGVFAFSVMIGQMRDVVGAATAGQTYYRSCMDSTVKYMNFYKIPRSVQNRVKTWYEYTWHSQGMLDESELMVQLPDKMRLDLAIDVNYSIVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVLGGPDGKSVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDKKDLNEILVHYPESQKLLRKKARRMLRNNNKPKEKSVLILPPRAGTPKLFNAALAAAGKMGAKGGRGGRLALLRARLKELAALEAAARQQQLLEQAKSSEDAAVGEEGSASPEQPPRPEPPAPEAPAPEPTAPEPLAPEAPAPEAPAPSSPPPASQERPEGDKDAARPEEHPVRIHVTLGPDPSEQILLVEVPEKQEEKEKKEEETEEKEEGEEARKEKEEE", "output": "Subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP (By similarity)."}]}
+{"id": "function_test_348", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGTSFFLGNYWLFFSVYLLVFLVGLPLNVMALVVFVGKLRRRPVAVDLLLLNLTISDLLLLLFLPFRMVEAACGMRWLLPFIFCPLSGFLFFTTIYLTSLFLTAVSIERFLSVAYPLWYKTRPRLAQAGLVSVVCWFLASAHCSVVYITEYWGNATYSQGTNGTCYLEFREDQLAILLPVRLEMAVVLFMVPLCITSYCYSRLVWILSRGASRRRRKRIMGLLAATLLIFFVCFGPYNMSHVVGYVSRESPSWRSYVLLLSTLNSCIDPLVFYFSSSKFQADFHQLLGRLLRTCVPWTQQVSLELKVKNGEEPSKECPS", "output": "G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. In omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. SCFAs serve as a source of energy but also act as signaling molecules. That G protein-coupled receptor is probably coupled to the pertussis toxin-sensitive, G(i/o)-alpha family of G proteins. Its activation results in the formation of inositol 1,4,5-trisphosphate, the mobilization of intracellular calcium, the phosphorylation of the MAPK3/ERK1 and MAPK1/ERK2 kinases and the inhibition of intracellular cAMP accumulation. Activated by SCFAs and by beta-hydroxybutyrate, a ketone body produced by the liver upon starvation, it inhibits N-type calcium channels and modulates the activity of sympathetic neurons through a signaling cascade involving the beta and gamma subunits of its coupled G protein, phospholipase C and MAP kinases. Thereby, it may regulate energy expenditure through the control of the sympathetic nervous system that controls for instance heart rate . Upon activation by SCFAs accumulating in the intestine, it may also signal to the brain via neural circuits which in turn would regulate intestinal gluconeogenesis. May also control the production of hormones involved in whole-body energy homeostasis. May for instance, regulate blood pressure through renin secretion . May also regulate secretion of the PYY peptide by enteroendocrine cells and control gut motility, intestinal transit rate, and the harvesting of energy from SCFAs produced by gut microbiota . May also indirectly regulate the production of LEP/Leptin, a hormone acting on the CNS to inhibit food intake, in response to the presence of short-chain fatty acids in the intestine . Finally, may also play a role in glucose homeostasis . Besides its role in energy homeostasis, may play a role in intestinal immunity. May mediate the activation of the inflammatory and immune response by SCFAs in the gut, regulating the rapid production of chemokines and cytokines by intestinal epithelial cells . Exhibits an SCFA-independent constitutive G protein-coupled receptor activity ."}]}
+{"id": "function_test_349", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPHFTVVPVDGPRRGDYDNLEGLSWVDYGERAEREDSDGQGNHRENSPFLSPLDASRGNDYYDRNLALFEEELDIRPKVSSLLGKLVSYTNLTQGAKEHEEAESGEGGRRRAAKAPSMGTLMGVYLPCLQNIFGVILFLRLTWMVGTAGVLQALLIVLICCCCTLLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGLCFYLGTTFAAAMYILGAIEILLTYIAPPAAIFYPSGTHDMSSATLNNMRVYGTIFLTFMTLVVFVGVKYVNKFASLFLACVIISILSIYVGGIKSAFDPPVFPVCMLGNRTLSRDQFDICAKTVVVDNETVATRLWTFFCHSPNLTADSCDPYFLLNNVTEIPGIPGAAAGVLQENLWSAYLEKGEVVEKHGLPSTDTLGLKESLSLYVVADIATSFTVLVGIFFPSVTGIMAGSNRSGDLRDAQKSIPVGTILAIVTTSLVYFSSVILFGACIEGVVLRDKYGDGVSRNLVVGTLAWPSPWVIVVGSFFSTCGAGLQSLTGAPRLLQAIAKDNIIPFLRVFGHGKANGEPTWALLLTALIAELGILIASLDMVAPILSMFFLMCYLFVNLACAVQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFVSSWYYALVAMVIAGMIYKYIEYQGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLLKLDEDLHVKYPRLLTFASQLKAGKGLTIVGSVIQGSFLESYGEAQAAEQTIKNMMEIEKVKGFCQVVVASKVREGLAHLIQSCGLGGMRHNSVVLGWPYGWRQSEDPRAWKTFIDTVRCTTAAHLALLVPKNIAFYPSNHERYLEGHIDVWWIVHDGGMLMLLPFLLRQHKVWKKCRMRIFTVAQMDDNSIQMKKDLAIFLYHLRLEAEVEVVEMHNSDISAYTYERTLMMEQRSQMLRQMRLTKTERDREAQLVKDRHSALRLESLYSDEEDESVTGADKIQMTWTRDKYMAEPWDPSHAPDNFRELVHIKPDQSNVRRMHTAVKLNEVIVTRSHDARLVLLNMPGPPKNSEGDENYMEFLEVLTEGLERVLLVRGGGREVITIYS", "output": "Mediates electroneutral potassium-chloride cotransport when activated by cell swelling . May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl(-) exit in NaCl absorbing epithelia (Probable)."}]}
+{"id": "function_test_350", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSEDSSALPWSINRDDYELQEVIGSGATAVVQAAYCAPKKERVAIKRINLEKCQTSMDELLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDEPTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQKAKNKEFLQEKILQRAPTISERSKKVRRVPGSSGRLHKTEDGGWEWSDDEFDEESEEGRAAISQLRSPRVKDSLSSSELFAAAEPMGTLLQVPEQISAHLPQPAGQMPTQPAQVSLLPPAEPAKPAQAQSSGERSQETKIPISLVLRLRNSKKELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLVIVAANLQKIVEEPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQLSIS", "output": "Phosphorylates RELL1, RELL2, RELT and PAK1. Phosphorylates PLSCR1 in the presence of RELT."}]}
+{"id": "function_test_351", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAFCTQLMLLLWKNYTYRRRQPIQLVVELLWPLFLFFILVAVRHSHPPLEHHECHFPNKPLPSAGTVPWLQGLVCNVNNSCFQHPTPGEKPGVLSNFKDSLISRLLADAHTVLGGHSTQDMLAALGKLIPVLRAVGSGAWPQESNQPAKQGSVTELLEKILQRASLETVLGQAQDSMRKFSDATRTVAQELLTLPSLVELRALLRRPRGSAGSLELISEALCSTKGPSSPGGLSLNWYEANQINEFMGPELAPTLPDSSLSPACSEFVGALDDHPVSRLLWRRLKPLILGKILFAPDTNFTRKLMAQVNQTFEELALLRDLHELWGVLGPQIFNFMNDSTNVAMLQKLLDVEGTGWQQQTPKGQKQLEAIRDFLDPSRGRYNWQEAHADMGRLAEILGQILECVSLDKLEAVPSEEALVSRALELLGERRLWAGIVFLSPEHPLDSSEPPSPTTTGPGHLRVKIRMDIDDVTRTNKIRDKFWDPGPSADPLMDLRYVWGGFVYLQDLLEQAAVRVLSGRDSRAGLYLQQMPHPCYVDDVFLRVLSRSLPLFLTLAWIYSVALTVKAVVREKETRLRETMRAMGLSRAVLWLGWFLSCLGPFLVSAALLVLVLKLGNILPYSHPVVVFLFLAAFAVATVAQSFLLSAFFSRANLAAACGGLAYFALYLPYVLCVAWRERLPLGGLLAVSLLSPVAFGFGCESLALLEEQGDGAQWHNLGTGPAEDVFSLAQVSAFLLLDAVIYGLALWYLEAVCPGQYGIPEPWNFPFRRSYWCGPGPPKSSVLAPAPQDPKVLVEEPPPGLVPGVSIRGLKKHFRGSPQPALRGLNLDFYEGHITAFLGHNGAGKTTTLSILSGLFPPSSGSASILGHDVQTNMAAIRPHLGICPQYNVLFDMLTVEEHVWFYGRLKGVSAAAIDSEQEHLIRDVGLIPKRDTQTRHLSGGMQRKLSVAIAFVGGSRVVIMDEPTAGVDPASRRGIWELLLKYREGRTLILSTHHLDEAELLGDRVAMVASGSLCCCGSPLFLRRHLGCGYYLTLVKSSQSLVTHDLKGDTEDPRREKKSGSEGKTADTVLTRDGPHRSSQVPAPDAVPVTPSAALILELVQRHVPGAQLVEELPHELVLALPYAGALDGSFATVFQELDQQLERLGLTGYGISDTNLEEIFLKVVEEAHAHGEGGDPRQQQHLLTATPQPHTGPEASVLENGELAKLVLDPQAPKGSAPTTAQVQGWTLTCQQLRALLHKRFLLARRSRRGLFAQIVLPALFVGLALFFTLIVPPFGQYPPLQLSPAMYGPQVSFFSEDAPADPNRMKLLEALLGEAGLQDPSVQGKGSRGSECTHSLACYFTVPEVPPDVASILASGNWTPDSPSPACQCSQPGARRLLPDCPAGAGGPPPPQAMAGFGEVVQNLTGRNVSDFLVKTYPSLVRRGLKTKKWVDEVRYGGFSLGGRDPDLPSGREVVRTVAEMRALLSPQPGNTLDRILNNLTQWALGLDARNSLKIWFNNKGWHAMVAFVNRANNGLLRAFLPSGSVRHAHSITTLNHPLNLTKEQLSEATLIASSVDVLVSICVVFAMSFVPASFTLVLIEERITRAKHLQLVSGLPQTLYWLGNFLWDMCNYLVAVCIVVLIFLAFQQKAYVAPENLPALLLLLLLYGWSITPLMYPASFFFSVPSTAYVVLTCINLFIGINSSMATFVLELLSDQNLQEVSRILKQVFLIFPHFCLGRGLIDMVRNQAMADAFERLGDKQFQSPLRWDIIGKNLLAMVAQGPLFLLITLLLQHRNRLLPQPKSRLPPPLGEEDEDVVRERERVTKGATQGDVLVLRDLTKVYRGQRSPAVDHLCLGIPPGECFGLLGVNGAGKTSTFRMVTGDTLPSSGEAVLAGHNVAQEPSAAHRSMGYCPQSDAIFDLLTGREHLELFARLRGVPEAQVAQTALSGLVRLGLPSYADRPAGTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNNLLSVVREGRSVVLTSHSMEECEALCTRLAIMVNGRFRCLGSAQHLKSRFGAGHTLTLRVPPDQPEPAIAFIVTTFPDAELREVHGSRLRFQLPPGGGCTLARVFRELAAQGKAHGVEDFSVSQTTLEEVFLYFSKDQGEEEEGSGQETETREVSTPGLQHPKRVSRFLEDPSSVETVI", "output": "ATP-binding cassette (ABC) transporter that plays a role in lipid homeostasis and macrophage-mediated phagocytosis (By similarity). Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells (By similarity). May also mediate cholesterol efflux (By similarity). May regulate cellular ceramide homeostasis during keratinocyte differentiation (By similarity). Involved in lipid raft organization and CD1D localization on thymocytes and antigen-presenting cells, which plays an important role in natural killer T-cell development and activation (By similarity). Plays a role in phagocytosis of apoptotic cells by macrophages (By similarity). Macrophage phagocytosis is stimulated by APOA1 or APOA2, probably by stabilization of ABCA7 (By similarity). Also involved in phagocytic clearance of amyloid-beta by microglia cells and macrophages (By similarity). Further limits amyloid-beta production by playing a role in the regulation of amyloid-beta A4 precursor protein (APP) endocytosis and/or processing (By similarity)."}]}
+{"id": "function_test_352", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGLWGMLAFPLGFLLASVLLVASAPATPESPGCSNKEQQVTVSHTYKIDVPKSALVQVETDPQSLSDDGTSLLAPGEDGEEQNIIFRHNIRLQTPQKNCDLADSVQDLLARMKKLEEEMAELKEQCNTNRCCQGAADLSRHCSGHGTFLPETCSCHCDQGWEGADCDQPTCPGACNGHGRCVDGQCVCDAPYVGVDCAYAACPQDCSGHGVCVQGVCQCHEDFTAEDCSEQRCPGDCSGNGFCDTGECYCEMGFTGPDCSQVVAPQGLQLLKSTENSLLVSWEPSSEVDYYLLSYYPLGKEQATKQVRVPKEQHTYDITGLLPGTKYIVTLRNVKKDISSSPQHLLATTDLAVVGTAWVNEETETSLDVEWENPLTEVDYYKLRYGPLTGQEVTEVTVPKSRDPKSRYDITGLQPGTEYKITVVPIRGDLEGKPILLNGRTEIDGPTNVVTNQVTEDTASVSWDPVRADIDKYVVRYIAPDGETKEKAVPKDQSSTVLTGLKPGEAYKVFVWAERGNQGSKKADTKALTEIDSPENLVTDRVTENSLSVSWDPVEADIDRYVVSYTSVDGETKQVPVKKDQRSTVLTGLSPGVEYKVYVWAEKGDRESKKANTKAPTDIDSPKNLVTDQVTENTLSVSWDPVQANIDRYMVSYTSADGETREVPVPKEKSSTVLTGLRPGVEYKVHVWAQKGTQESRKANTKAPTDIDGPKNLVTDQVTETTLSVSWDPVEADIDRYMVRYTSPDGETKEVPVSKDKSSTVLRGLRPGVEYKVDVWAQKGAQDSRKANTKAPTDIDSPKNLVTEQVTESTATVSWDPVEADIDRYVVRYTSVDGETREFLVGKDQTSTVLTGMRPGVEYQVDVWAQKGTQESRKTSTKAPTDIDGPKNLVTDQVTETTLSVSWDPVEADIDRYMVRYTSPDGETKEVPVSKDKSSTVLRGLRPGVEYKVDVWAQKGAQDSRKANTKAPTDIDSPKNLAIDQVTETTLSVSWDPVQADIDRYVVRYTSADGESKEFLIGKEQRSTVLTGLRPGVEYKVEVWAQKGARESKKANTEGHTDIDSPKNLVTNQVTENTATISWDPVQADIDRYMVRYTSADGETREIPVRKEKSSTVLTGLRPGVEYTVQVWAQKGARESKKAKTKAPTEIDSPKNLVTNRVTENTATISWDPVRANIDRYMVRYTSADGETKEIPVSKDQSSTILTGLKPGMEYTIHVWAQKGARESKKADTKALTEIDPPRNLRPFGVTHSGGVLTWLPPSAQIDGYILTYQFPNGTVKEVELPRGQQRFELQDLEQGVTYPVSLVAFKGNQRSRTVSTTLSTVDARFPHPSDCSQVQQNTNAASGLYTIYLNGDASRPMQVYCDMDTDGGGWIVFQRRNTGQLDFFKRWRSYVEGFGDPMKEFWLGLDKLHNLTTGTTTRYEVRADLQTFNESAYAVYDFFQVASSKERYKLSVGKYRGTAGDALTYHNGWKFTTFDRDNDIALSNCALTHHGGWWYKNCHLANPNGKYGETKHSEGVNWEPWKGHEFSIPYVELKIRPFGYSRDRFSGRKKRSIGKARMF", "output": "Extracellular matrix protein that seems to be a ligand for ITGA8:ITGB1, ITGAV:ITGB1 and ITGA4:ITGB1 (By similarity) . Involved in neurite outgrowth and cell migration in hippocampal explants . During endochondral bone formation, inhibits proliferation and differentiation of proteoblasts mediated by canonical WNT signaling . In tumors, stimulates angiogenesis by elongation, migration and sprouting of endothelial cells (By similarity). Expressed in most mammary tumors, may facilitate tumorigenesis by supporting the migratory behavior of breast cancer cells ."}]}
+{"id": "function_test_353", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MMVNHNNGQRPTDIDSRLRQTEQDKLLFHDFLGSKNPTLASTSMADHRLPPDNKAAKAAMTPSTASASSAGGLGGLSSTSDLVERHSGGGNHLDGIQLFGPRSDVSGSIMSNRFSGNKRSNSDSHFTTQEHPETLHWSKLLRNGPGSFSMNVNPLANQPPRGGGQISHLLHQLSTSRFKDENVGPSVIAQTAADEGSRTGMKGPGILSSFTMPNSSKLESFAPSNTGNRKDLASSTKQMTIFYGGQAHVFDDVHPNKADVIMALAGSSGGSWSTGLSHKPKSKNNTSDGPYKLGQMYEGGSSKETPQMPPEFRARPSHQPTSSACHRIFTQPGREHQGSIISRGRDIRDPVHRSDPEKEAT", "output": "Repressor of jasmonate responses."}]}
+{"id": "function_test_354", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MARFSTYIIFTSVLCQLTVTAASGTLKKVAGALDGSVTFTLNITEIKVDYVVWTFNTFFLAMVKKDGVTSQSSNKERIVFPDGLYSMKLSQLKKNDSGAYRAEIYSTSSQASLIQEYVLHVYKHLSRPKVTIDRQSNKNGTCVINLTCSTDQDGENVTYSWKAVGQGDNQFHDGATLSIAWRSGEKDQALTCMARNPVSNSFSTPVFPQKLCEDAATDLTSLRGILYILCFSAVLILFAVLLTIFHTTWIKKGKGCEEDKKRVDRHQEMPDLCPHLEENADYDTIPYTEKRRPEEDAPNTFYSTVQIPKVVKSPSSLPAKPLVPRSLSFENVI", "output": "Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2 . Mediates natural killer (NK) cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway (By similarity). Positively regulates NK cell functions by a mechanism dependent on the adapter SH2D1B. In addition to heterotypic NK cells-target cells interactions also homotypic interactions between NK cells may contribute to activation. However, in the absence of SH2D1B, inhibits NK cell function. Acts also inhibitory in T-cells . May play a role in lymphocyte adhesion (By similarity). In LPS-activated monocytes negatively regulates production of pro-inflammatory cytokines (By similarity)."}]}
+{"id": "function_test_355", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLPGWELTLCLLVSLGFHFRSFYEVYKVSREHEEELDQEFELEMDTLFGGLKKDPTDFEWNFWMEWGKRRLVWLFIGHMAVSQLATLLTKKHRPWIVMVYGMWACWCVLGAPGVVMVLLHSTIAFCVAQFRSVLLSWLCSLLLLSTLRLQSVEEVKRRWYKTENEYYLLQFTLTVRCLYYTSFSLELCRQPPSAQPTPSAQGASHSYPWLLTYVFYYPVFHNGPILNFPEFFRQMQQPELNSLQHSLCIVAKGLGRLLCWWWLAELMVHLMYMHALYSSAPLLESVSCWTLGGLALAQVLFFYVKYLVLFGVPALLMRLDGLTPPPLPRCVSTMFSFTGMWRYFDVGLHNFLIRYVYIPLGGSQHGLLGTLLSTATTFAFVSYWHGSYEDLWCWAALNWLGVTVESGVRRLLETPCVRETLARHLSPQAHHRLHALLAACSTSMLILFNLVFLGGIQVGKTYWNRIFLQGWPWVTLSVLGFLYCYSHVDIAWAQTYTVL", "output": "Palmitoyl acyltransferase that catalyzes N-terminal palmitoylation of SHH; which is required for SHH signaling during limb development . It also catalyzes N-terminal palmitoylation of DHH (By similarity). Promotes the transfer of palmitoyl-CoA from the cytoplasmic to the luminal side of the endoplasmic reticulum membrane, where SHH palmitoylation occurs (By similarity). Plays a role in proper testis cord formation and the differentiation of Leydig cells ."}]}
+{"id": "function_test_356", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQHGDRNTPGYREGIMSAVSLRRPSAPKGFALSVHVVTWNVASAAPTVDLSDLLQLNNQDLNLDIYIIGLQEMNFGIISLLSDAAFEDPWSSLFMDMLSPLNFVKISQVRMQGLLLLVFAKYQHLPYIQIISTKSTPTGLYGYWGNKGGVNVCLKLYGYYVSIINCHLPPHMYNNDQRLEHFDRILESLTFEGYDVPNILDHDLILWFGDMNFRIEDFGLLFVQESITRKYYKELWEKDQLFIAKKNDQLLREFQEGPLLFPPTYKFDRHSNNYDTSEKKRKPAWTDRILWRLKRQPSQASPLASSVPTSYFLLTLKNYVSHMAYSISDHKPVTGTFDLELNPLMSVPLITMMPEHLWTMENDMLISYTSTPEFLSSSWDWIGLYKVGMRHINDYVAYVWVGDNQVSYGNNPNQVYINISAIPDTEDQFLLCYYSNNLHSVVGISQPFKIPIRSFLREDTLYEPEPQI", "output": "Inositol 5-phosphatase which acts on inositol 1,4,5-trisphosphate, inositol 1,3,4,5-tetrakisphosphate, phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Has 6-fold higher affinity for phosphatidylinositol 4,5-bisphosphate than for inositol 1,4,5-trisphosphate (By similarity). Negatively regulates assembly of the actin cytoskeleton. Controls insulin-dependent glucose uptake among inositol 3,4,5-trisphosphate phosphatases; therefore, is the specific regulator for insulin signaling in skeletal muscle ."}]}
+{"id": "function_test_357", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MATTSTTGSTLLQPLSNAVQLPIDQVNFVVCQLFALLAAVWFRTYLHSSKTSSFIRHVVATLLGLYLAFFCFGWYALHFLVQSGISYCIMIIAGVESMQQCCFVFALGYLSVCQITRVYIFDYGQYSADFSGPMMIITQKITSLAYEIHDGMFRKDEELTPSQRGLAVRRMPSLLEYVSYTCNFMGILAGPLCSYKDYIAFIEGRASHVAQPSENGKDEQHGKADPSPNAAVTEKLLVCGLSLLFHLTISNMLPVEYNIDEHFQATASWPTKATYLYVSLLAARPKYYFAWTLADAINNAAGFGFRGYDKNGVARWDLISNLRIQQIEMSTSFKMFLDNWNIQTALWLKRVCYERATFSPTIQTFFLSAIWHGVYPGYYLTFLTGVLMTLAARAVRNNFRHYFLEPPQLKLFYDLITWVATQITISYTVVPFVLLSIKPSFTFYSSWYYCLHVCSILVLLLLPVKKSQRRTSTQENVHLSQAKKFDERDNPLGQNSFSTMNNVCNQNRDTGSRHSSLTQ", "output": "Acyltransferase which catalyzes the transfert of an acyl group from an acyl-CoA to a lysophospholipid leading to the production of a phospholipid and participates in the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle . Catalyzes the acylation of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) and to a lesser extend lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE) . Does not acylates lysophosphatidic acid (LPA) and lysophosphatidylserine . Prefers oleoyl-CoA as the acyl donor . May be involved in chondrocyte differentiation ."}]}
+{"id": "function_test_358", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MFRLNTLSALAELAVGSRWYHGASQPTQTKRRLMLVAFLGASAVTASTGLLWKKAHAESPPCVNSKKPDTEDKERNKDSGEVSSREGRAADAAAEPYPEDKKKKRSGFRDRKVMEYENRIRAYSTPDKIFRYFATLKVINEPGETEVFMTPQDFVRSITPNEKQPEHLGLDQYIIKRFDGKKIAQEREKFADEGSIFYSLGECGLISFSDYIFLTTVLSTPQRNFEIAFKMFDLNGDGEVDMEEFEQVQSIIRSQTSMGMRHRDRPTTGNTLKSGLCSALTTYFFGADLKGKLTIKNFLEFQRKLQHDVLKLEFERHDPVDGRISERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKDGKGLTFQEVENFFTFLKNINDVDTALSFYHMAGASLDKVTMQQVARTVAKVELSDHVCDVVFALFDCDGNGELSNKEFVSIMKQRLMRGLEKPKDMGFTRLMQAMWKCAQETAWDFALPK", "output": "Key regulator of mitochondrial calcium uniporter (MCU) that senses calcium level via its EF-hand domains . MICU1 and MICU2 form a disulfide-linked heterodimer that stimulates and inhibits MCU activity, depending on the concentration of calcium . MICU1 acts both as an activator or inhibitor of mitochondrial calcium uptake (By similarity). Acts as a gatekeeper of MCU at low concentration of calcium, preventing channel opening (By similarity). Enhances MCU opening at high calcium concentration, allowing a rapid response of mitochondria to calcium signals generated in the cytoplasm . Regulates glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake (By similarity). Induces T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG (By similarity)."}]}
+{"id": "function_test_359", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MELSAIGEQVFAVESIRKKRVRKGKVEYLVKWKGWPPKYSTWEPEEHILDPRLVMAYEEKEERDRASGYRKRGPKPRRLLLQESAAPDVVQTPGDWEPMEQAPEEEAEADLTNGPPPWTPTLPSSEVTVTDITANSVTVTFREAQAAEGFFRDRNEKL", "output": "Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development . PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3) (By similarity). Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3) . Trimethylation at 'Lys-27' (H3K27me3) is important for chromatin recruitment . May possibly also bind trimethylated lysine residues in other proteins (in vitro) . Binds non-coding, single-stranded RNA and double-stranded RNA . Plays a role in the timely repression of differentiation-specific genes in pluripotent embryonic stem cells to maintain the undifferentiated state . Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity ."}]}
+{"id": "function_test_360", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAAEASSTGLASCHLVESKSGAQGASGCQCTRCGRKVSVASGDHHKFPCGHAFCELCLLAPQEYTTSKCTDCEVHTTVSMNQGHYPVDGFIEEDSSLEALPPKMVNNCSSDLEKTVDQLINDLEHSSSIHRNVSNPSAVMSETEEIDEALKIAGCNFEQLSNAIKMLDSTQDQTRQETHSLTEAVEKQFDTLLASLDSRKKSLCEELIRRTDDYLSKLVTVKSYIEEKKSDLDAAMKIAKELRSAPSLRTYCDLTQIIRTLKLTFESELSQVSSIIPRNTPRLDINCSEAICMFSSMGKIEFEDSTKCYPQENEDGQNVQKKFNNRKELCCDVYSSLEKKKVDAAVLTDETPEPPLQAEAPDRHLEGKKKQPTKEMVVVTSPKTIAVLPQLGSSPDVIIEEIIEENLESCFTDDPIETSGYPKKPPQKEQSAPVGSKAGCPELVFVSHVIHPCHFYVRKYSQIKDATILEKKMKQVCNRSLHLDPSDILELGARIFVNSIKNRMWCRGIITEIIPSKTKNIRKPCSPTKFSVCEISLIQIFMVDFGNSEVLIITGVGDTHEGPEHDGEQHITLSDFCLLLMKSEPYSEELLKDIPHLAHLCSLKDIVPYNSTEGWEKEAKVEFLKMVNKKAVLMKVFGEEDDVLIVDLQKPPTNKISSDMPVSLRDALVFMELARFRSQSPRSHSEKNTTLCYHPPILPEEMTEVSVMVCHINSPTDFYLQLMENLDFLSLLKTIEEFYKGEDGENLEILCPLQNQACVAKFEDGIWYRAKVIGLPGHREVEVKYVDFGNTAKITLKDMRKIKDEFLEPPEKAIKCKLAYVEPSKKSQWSKKAKEKFEEKTQDKFVTCSVIKILENNVLLVELFDSRAPGKSAVSINDQLVKEGLASYEAGYTLKDNSKKHLEVWDPSPEEIITSEINNLSPLSVKSLPNENFQSLYNKELPVNICNVISPEKIYVQWLLTENLLNSLEEKMVAAYEHSEWKPVKWECDMHCAVKVPAKNQWRRGQILRMVTDKLVEVLLYDVGVELVVNIHCLRELQENLKTMGRLSLECSLVDIRPTGGSDKWTATACDCLSLHLTGAIATIILQESNTTWPLPVKIFCRDEKGERVDVSKYLIKKGLALRERRVSKSSNSHSPEKSLEIPLEQGDSVVTKCFKINFDTNKKIADKVNEHKVPDSKGKKSESRSTGCYRPPAVPNTSSFEAIVTCIGDDGTIFVVPKLSEFELIKMMDEIQSNLKCLGLLEPYSWKKGEPCAVRGSDTLWYRGKVMEVVGGTIRVQYLDHGFTEKIPQCHLYPILLYPDTPQFCIPCQLYQTLPVGNTWQPDAIELLQELLSKREVDIHIMELPNNSWGKLSVHLYFDGMSLSHFMAHHKYCIFEHTEEIFKEKPRGQNKKYEDENWKIRFEDLLLPEMEAPVLPPYLSSLLPPPEELFAVQVKHIVSPDEMYICLDSEDSYTQFNHHGDTDDSGVSWESESENLEEALQRFNKNVETFPPLTDFSSEMPCLAEYADGLWYRAKIISIKEFNPLSVLVLFVDYGCTEKLTINRLRQIPVQLMQYPAQAIKVLLAGFKPPLSDSGKTRIPYCPKWSMEALWTMIDCLQGKQLYASSVAQAPEQIVTLYEDEQYPVHMSLVEMGLADKDE", "output": "Seems to be involved in regulation of transcriptional activity of MYC. In vitro, inhibits DNA-binding activity of Mad-MAX heterodimers. Can recruit Mad transcriptional repressors (MXD1, MXD3, MXD4 and MXI1) to the cytoplasm. May be involved in spermiogenesis."}]}
+{"id": "function_test_361", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNHTSQAFITAASGGQPPNYERIKEEYEVAEMGAPHGSASVRTTVINMPREVSVPDHVVWSLFNTLFMNFCCLGFIAYAYSVKSRDRKMVGDVTGAQAYASTAKCLNISTLVLSILMVVITIVSVIIIVLNAQNLHT", "output": "IFN-induced antiviral protein which disrupts intracellular cholesterol homeostasis. Inhibits the entry of viruses to the host cell cytoplasm by preventing viral fusion with cholesterol depleted endosomes. May inactivate new enveloped viruses which buds out of the infected cell, by letting them go out with a cholesterol depleted membrane. Active against multiple viruses, including influenza A virus, SARS coronaviruses (SARS-CoV and SARS-CoV-2), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1), hepatitis C virus (HCV) and vesicular stomatitis virus (VSV) . Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV and SARS-CoV-2 S protein-mediated viral entry and VSV G protein-mediated viral entry . Plays a critical role in the structural stability and function of vacuolar ATPase (v-ATPase). Establishes physical contact with the v-ATPase of endosomes which is critical for proper clathrin localization and is also required for the function of the v-ATPase to lower the pH in phagocytic endosomes thus establishing an antiviral state. In hepatocytes, IFITM proteins act in a coordinated manner to restrict HCV infection by targeting the endocytosed HCV virion for lysosomal degradation. IFITM2 and IFITM3 display anti-HCV activity that may complement the anti-HCV activity of IFITM1 by inhibiting the late stages of HCV entry, possibly in a coordinated manner by trapping the virion in the endosomal pathway and targeting it for degradation at the lysosome. Exerts opposing activities on SARS-CoV-2, including amphipathicity-dependent restriction of virus at endosomes and amphipathicity-independent enhancement of infection at the plasma membrane."}]}
+{"id": "function_test_362", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTTLDDKLLGEKLQYYYSTSEDEDSDHEDKDRGRGAPAISSTPAEAELAGEGISINTGPKGVINDWRRFKQLETEQREEQCREMERLIKKLSMSCRSHLDEEEEQQKQKDLQEKISGKMTLKEFGTKDKNLDDEEFLQQYRKQRMEEMRQQFHKGPQFKQVFEIPSGEGFLDMIDKEQKSTLIMVHIYEDGVPGTEAMNGCMICLATEYPAVKFCRVRSSVIGASSRFTRNALPALLIYKAGELIGNFVRVTDQLGEDFFAVDLEAFLQEFGLLPEKEVLVLTSVRNSATCHSEDSDLEID", "output": "Functions as a co-chaperone for CCT in the assembly of heterotrimeric G protein complexes, facilitates the assembly of both Gbeta-Ggamma and RGS-Gbeta5 heterodimers . Acts also as a positive regulator of hedgehog signaling and regulates ciliary function ."}]}
+{"id": "function_test_363", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MVAAMVAALRGPSRRFRPRTRALTRGTRGAASAAGGQQSFDLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCVNVGCIPKKLMHQAALLGGMIRDAHHYGWEVAQPVQHNWKTMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVRGVDKGGKATLLSAEHIVIATGGRPRYPTQVKGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTVMMRSIPLRGFDQQMSSLVTEHMESHGTQFLKGCVPSHIKKLPTNQLQVTWEDHASGKEDTGTFDTVLWAIGRVPETRTLNLEKAGISTNPKNQKIIVDAQEATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQRLFGKSSTLMDYSNVPTTVFTPLEYGCVGLSEEEAVALHGQEHVEVYHAYYKPLEFTVADRDASQCYIKMVCMREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMQTVGIHPTCSEEVVKLHISKRSGLEPTVTGCUG", "output": "Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis (By similarity). Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling (By similarity)."}]}
+{"id": "function_test_364", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFVRIGFVVAASIAAVTVKRLNVKPSKPSKPSDNGEGGDKEQSVDPDYNLNDKNLQEEEEEEEEEVKLINSVINQTRGSFSDYLDDDILPEFEDLLSGEIEYPLPDDDNNLEKAEKERKYEVEMAYNDGELERLKQLVKELEEREVKLEGELLEYYGLKEQESDIVELQRQLKIKTVEIDMLNITINSLQAERKKLQEELSQNGIVRKELEVARNKIKELQRQIQLDANQTKGQLLLLKQHVSSLQMKEEEAMNKDTEVERKLKAVQDLEVQVMELKRKNRELQHEKRELSIKLDSAEARIATLSNMTESDKVAKVREEVNNLKHNNEDLLKQVEGLQMNRFSEVEELVYLRWVNACLRYELRNYQTPAGKISARDLSKNLSPKSQAKAKRLMLEYAGSERGQGDTDLESNYSQPSSPGSDDFDNASMDSSTSRFSSFSKKPGLIQKLKKWGKSKDDSSVQSSPSRSFYGGSPGRLSSSMNKQRGPLESLMIRNAGESVAITTFGQVDQESPGTPETPNLPRIRTQQQASSPGEGLNSVAASFHVMSKSVDNVLDEKYPAYKDRHKLAVEREKHIKHKADQARAERFGGNVALPPKLAQLKEKRVVVPSVITATGDQSNESNESNEGKASENAATVTKMKLVDIEKRPPRVPRPPPRSAGGGKSTNLPSARPPLPGGGPPPPPPPPGGGPPPPPGGGPPPPPPPPGALGRGAGGGNKVHRAPELVEFYQSLMKRESKKEGAPSLISSGTGNSSAARNNMIGEIENRSTFLLAVKADVETQGDFVQSLATEVRASSFTDIEDLLAFVSWLDEELSFLVDERAVLKHFDWPEGKADALREAAFEYQDLMKLEKQVTSFVDDPNLSCEPALKKMYKLLEKVEQSVYALLRTRDMAISRYKEFGIPVDWLSDTGVVGKIKLSSVQLAKKYMKRVAYELDSVSGSDKDPNREFLLLQGVRFAFRVHQFAGGFDAESMKAFEELRSRAKTESGDNNNNNNNNSNEEESVN", "output": "Required for the positioning and movement of chloroplasts. Interacts with profilin and actin independent of its polymerization status. Regulates chloroplast localization by anchoring chloroplasts to the plasma membrane and forming a bridge to the actin cytoskeleton."}]}
+{"id": "function_test_365", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSSESPNLPAAAGTVPDNHPPPPPVVTAAEAGSDDSPKGVASKLSAAGISNWAKNLKVPQPFASTQNDSGVENTEKSAFAKFTSGLGIRLSPKSPQTNDTTTEGTSSATESSFIGTITKGLVDTSKNAVKAVQVKARHAVSQNKRRYQEGGFDLDLTYITENIIAMGFPAGDMSSGFFGYVEGFYRNQMEEVINFLETQHKGKYKVYNLCSERLYDVSLFEGKVASFPFDDHNCPPIHLVTSFCQSAYSWLKEDIENVVVVHCKAGMARTGLMICSLLLYLKFFPTAEECMDFYNQKRCVDGKGLVLPSQIRYVKYFERILTYFNGENQPGRRCMLRGFRLHRCPYWIRPSITISDHNGVLFTTKKHPRTKDLSPEDFWFSAPKKGVMVFALPGEPGLTELAGDFKIQFHDRQGDFYCWLNTTMMENRVILKTSELDGFDKRKLPSPGFMVEVVLADINATIPTNPSSETASKTPEETSAANSSPVDGSASVPGPDKETENPDKDDVFSDNEGDSTGPTKTTSSASSQTPEAKKSADETAVLTKATEKVSISGNKGSSQPVQGVTVSKGEATEKPSGAGVNASSSSESEFKVMAADASVFSFGDEDDFESD", "output": "Binds phosphatidic acid. Protein tyrosine phosphatase that exhibits also lipid phosphatase activity. Hydrolyzed poorly p-nitrophenyl phosphate (p-NPP). Can use PtdIns isomers as substrates. Removes efficiently phosphate from the D3 position of the inositol ring, less from the D4 position and not at all from the D5 position on monophosphorylated PtdIns isomers (PIPs). The presence of a phosphate group in the D5 position on PIP(2) isomers reduces lipid phosphatase activity. Mostly active on PtdIns(3)P and PtdIns(3,4)P(2), to a lower extent, on PtdIns(4)P and PtdIns(3,5)P(2), but barely against PtdIns(3,4,5)P(3) as substrate."}]}
+{"id": "function_test_366", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEALKTATFSPMSVLSEKRSEPRKPFSLPNLFPPKSQRPISQESFLKRFNGGLALLTSVLSSATAPAKSLTYEEALQQSMTTSSSFDSDGLIEGISNFVTDNPLVIAGGVAALAVPFVLSQVLNKKPKSWGVESAKNAYTKLGTDDNAQLLDIRATADFRQVGSPNIKGLGKKAVSTVYNGEDKPGFLKKLSLKFKDPENTTLYILDKFDGNSELVAELVALNGFKSAYAIKDGAEGPRGWLNSSLPWIEPKKTLSLDLSSLTDSISGVFGESSDGVSVALGVAAAAGLSVFAFTEIETILQLLGSAALVQLAGKKLLFAEDRKQTLKQVDEFLNTKVAPKELVDELKEIGKALLPQSTSNKALPAPATVTAEAESATATTTTVDKPVPEPETVAATTTTVDKPVPEPEPVPEPVPVPAIEAAVAAQVITEPTETEAKPKPHSRPLSPYASYPDLKPPSSPMPSQP", "output": "Rhodanese domain-containing protein required for anchoring ferredoxin--NADP reductase to the thylakoid membranes and sustaining efficient linear electron flow (LEF)."}]}
+{"id": "function_test_367", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTAVLFLCFLLICFSFTPSLQNVSESEPLVRFKRSVNITKGDLNSWRTGTDPCNGKWFGIYCQKGQTVSGIHVTRLGLSGTINIEDLKDLPNLRTIRLDNNLLSGPLPPFFKLPGLKSLLLSNNSFSGEIADDFFKETPQLKRVFLDNNRLSGKIPASLMQLAGLEELHMQGNQFTGEIPPLTDGNKVLKSLDLSNNDLEGEIPITISDRKNLEMKFEGNQRLCGSPLNIECDEKPSSTGSGNEKNNTAKAIFMVILFLLIFLFVVAIITRWKKKRQPEFRMLGKDHLSDQESVEVRVPDSIKKPIDSSKKRSNAEGSSKKGSSHNGKGAGGGPGSGMGDIIMVNSEKGSFGLPDLMKAAAEVLGNGSLGSAYKAVMANGLSVVVKRIRDMNKLAREAFDTEMQRFGKLRHPNVLTPLAYHYRREEKLVVSEYMPKSSLLYVLHGDRGVYHSELTWATRLKIIQGVARGMDFLHEEFASYDLPHGNLKSSNVLLSETYEPLISDYAFLPLLQPNNASQALFAFKSPEFVQNQQVSPKSDVYCLGIIVLEVMTGKFPSQYLNTGKGGTDIVEWVQSSIAQHKEEELIDPEIASNTDSIKQMVELLRIGAACIASNPNERQNMKEIVRRIERVTL", "output": "Receptor-like kinase involved in the control of pollen germination and pollen tube polar growth . Can phosphorylate ROPGEF1 in vitro ."}]}
+{"id": "function_test_368", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MERTNSIEMDRERLTAEMAFRDSSSAVIRIRRRLPDLLTSVKLKYVKLGLHNSCNVTTILFFLIILPLTGTVLVQLTGLTFDTFSELWSNQAVQLDTATRLTCLVFLSFVLTLYVANRSKPVYLVDFSCYKPEDERKISVDSFLTMTEENGSFTDDTVQFQQRISNRAGLGDETYLPRGITSTPPKLNMSEARAEAEAVMFGALDSLFEKTGIKPAEVGILIVNCSLFNPTPSLSAMIVNHYKMREDIKSYNLGGMGCSAGLISIDLANNLLKANPNSYAVVVSTENITLNWYFGNDRSMLLCNCIFRMGGAAILLSNRRQDRKKSKYSLVNVVRTHKGSDDKNYNCVYQKEDERGTIGVSLARELMSVAGDALKTNITTLGPMVLPLSEQLMFLISLVKRKMFKLKVKPYIPDFKLAFEHFCIHAGGRAVLDEVQKNLDLKDWHMEPSRMTLHRFGNTSSSSLWYEMAYTEAKGRVKAGDRLWQIAFGSGFKCNSAVWKALRPVSTEEMTGNAWAGSIDQYPVKVVQ", "output": "Contributes to cuticular wax and suberin biosynthesis. Involved in both decarbonylation and acyl-reduction wax synthesis pathways. Elongase condensing enzyme mostly active with saturated fatty acids, especially with 16:0, 16:1, 18:0, and 20:0. Mediates the synthesis of VLCFAs from 20 to 26 carbons in length (e.g. C20:1, C20, C22, C24 and C26)."}]}
+{"id": "function_test_369", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLMSLTDSKEGKNRSGVRMFKDDDFLIPASGESWDRLRLTCSQPFTRHQSFGLAFLRVRSSLDSLSDPVKDPSSPGSSGLNQNSSDKLESDPSPWLTNPSIRRTFFPDPQTSTKEISALKGMLKQLQPGPLGRAARMVLSAAHKAPPASVVSPNNSHGEPDSSHPERAEPRAEEPNRKNNASRGKRRKVQEQRRPLSSSSSQPNRRATGRTKQRQQRPQAKSDGSGVQATGQCPICTGSFSIEALPRHAATCGESSPPQPASPTSLSSSESVLRCLHVALTPVPLIPKPNWTEIVNKKLKFPPTLLRAIQEGQLGLVQQLLESGSDPSGAGPGGPLRNVEESEDRSWREALNLAIRLGHEVITDVLLANVKFDFRQIHEALLVAVDTNQPAVVRRLLARLEREKGRKVDTKSFSLAFFDSSIDGSRFAPGVTPLTLACQKDLYEIAQLLMDQGHTIARPHPVSCACLECSNARRYDLLKFSLSRINTYRGIASRAHLSLASEDAMLAAFQLSRELRRLARKEPEFKPQYIALESLCQDYGFELLGMCRNQSEVTAVLNDLGEDSETEPEAEGLGQAFEEGIPNLARLRLAVNYNQKQFVAHPICQQVLSSIWCGNLAGWRGSTTIWKLFVAFLIFLTMPFLCIGYWLAPKSRLGRLLKIPVLKFLLHSASYLWFLIFLLGESLVMETQLSTFKGRSQSVWETSLHMIWVTGFLWFECKEVWIEGLRSYLLDWWNFLDVVILSLYLASFALRLLLAGLAYMHCRDASDSSTCRYFTTAERSEWRTEDPQFLAEVLFAVTSMLSFTRLAYILPAHESLGTLQISIGKMIDDMIRFMFILMIILTAFLCGLNNIYVPYQETEKLGNFNETFQFLFWTMFGMEEHSVVDMPQFLVPEFVGRAMYGIFTIVMVIVLLNMLIAMITNSFQKIEDDADVEWKFARSKLYLSYFREGLTLPVPFNILPSPKAAFYLLRRIFRFICCGSSCCKAKKSDYPPIPTFTNPGARAGPGEGEHVSYRLRVIKALVQRYIETARREFEETRRKDLGNRLTELTKTVSRLQSEVASVQKTVAAGGALRPPDGASILSRYITRVRNSFQNLGPPAPDTPAELTMPGIVETEVSLEDSLDATGEAGTPASGESSSSSSAHVLVHREQEAEGAGDLPLGEDLETKGES", "output": "Thought to form a receptor-activated calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Is not activated by intracellular calcium store depletion."}]}
+{"id": "function_test_370", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPVVSLAKVVTSPAVAGDLAVRVPFIYGKRLVSNRVSFGKLRRRSCIGQCVRSELQSPRVLGSVTDLALDNSVENGHLPKGDSWAVHKFGGTCVGNSERIKDVAAVVVKDDSERKLVVVSAMSKVTDMMYDLIHRAESRDDSYLSALSGVLEKHRATAVDLLDGDELSSFLARLNDDINNLKAMLRAIYIAGHATESFSDFVVGHGELWSAQMLAAVVRKSGLDCTWMDARDVLVVIPTSSNQVDPDFVESEKRLEKWFTQNSAKIIIATGFIASTPQNIPTTLKRDGSDFSAAIMSALFRSHQLTIWTDVDGVYSADPRKVSEAVVLKTLSYQEAWEMSYFGANVLHPRTIIPVMKYDIPIVIRNIFNLSAPGTMICRQIDDEDGFKLDAPVKGFATIDNLALVNVEGTGMAGVPGTASAIFSAVKEVGANVIMISQASSEHSVCFAVPEKEVKAVSEALNSRFRQALAGGRLSQIEIIPNCSILAAVGQKMASTPGVSATFFNALAKANINIRAIAQGCSEFNITVVVKREDCIRALRAVHSRFYLSRTTLAVGIIGPGLIGGTLLDQIRDQAAVLKEEFKIDLRVIGITGSSKMLMSESGIDLSRWRELMKEEGEKADMEKFTQYVKGNHFIPNSVMVDCTADADIASCYYDWLLRGIHVVTPNKKANSGPLDQYLKIRDLQRKSYTHYFYEATVGAGLPIISTLRGLLETGDKILRIEGIFSGTLSYLFNNFVGTRSFSEVVAEAKQAGFTEPDPRDDLSGTDVARKVTILARESGLKLDLEGLPVQNLVPKPLQACASAEEFMEKLPQFDEELSKQREEAEAAGEVLRYVGVVDAVEKKGTVELKRYKKDHPFAQLSGADNIIAFTTKRYKEQPLIVRGPGAGAQVTAGGIFSDILRLAFYLGAPS", "output": "Bifunctional aspartate kinase and homoserine dehydrogenase that catalyzes the first and the third steps toward the synthesis of the essential amino acids threonine, isoleucine, and methionine."}]}
+{"id": "function_test_371", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNSLHAHLLLLAVCCVGYIASSPVIGQDQRSGDSDADVLLAADEMADNGGDNIDKRVERYAFGLGRRAYMYTNGGPGMKRLPVYNFGLGKRSRPYSFGLGKRSDYDYDQDNEIDYRVPPANYLAAERAVRPGRQNKRTTRPQPFNFGLGRR", "output": "May act as a neurotransmitter or neuromodulator."}]}
+{"id": "function_test_372", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAQFPTPFGGSLDIWAITVEERAKHDQQFQSLKPISGFITGDQARNFFFQSGLPQPVLAQIWALADMNKDGRMDQVEFSIAMKLIKLKLQGYQLPPALPPVMKQQPAAISSAPAFGIGGMAGMPPLTAVAPVPMGSIPVVGMSPPLVSSVPQAAVPPLANGAPPVIQPLPAFAHPAATLPKSSSFSRSGPGSQLNTKLQKAQSFDVASAPAAAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTILMQSSLPQAQLASIWNLSDIDQDGKLTAEEFILAMHLIDVAMSGQPLPPVLPPEYIPPSFRRVRSGSGMSVISSSSADQRLPEEPSSEDEQQVEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELERQRQLEWERNRRQELLTQRNKDQEGIVVLKARRKTLEFELEALNDKKHQLEGKLQDIRCRLATQRQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQILSDQLKQVQQNSLHRDSLLTLKRALEAKELARQQLREQLDEVEKETRSKLQEIDVFNNQLKELREIHSKQQLQKQRSIEAERLKQKEQERKSLELEKQKEEGQRRVQERDKQWQEHVQQEEQQRPRKPHEEDKLKREDSVKKKEAEERAKPEVQDKQSRLFHPHQEPAKPAQAPWPTTEKGPLTISAQESAKVVYYRALYPFESRSHDEITIQPGDIVMVDESQTGEPGWLGGELKGKTGWFPANYAEKIPENEIPTPAKPVTDLTSAPAPKLALRETPAPLPVTSSEPSTTPNNWADFSSTWPSSTNEKPETDNWDTWAAQPSLTVPSAGQLRQRSAFTPATATGSSPSPVLGQGEKVEGLQAQALYPWRAKKDNHLNFNKSDVITVLEQQDMWWFGEVQGQKGWFPKSYVKLISGPVRKSTSIDTGPTEAPSSLKRVASPAAKPAIPGEEFVAMYTYESSEHGDLTFQQGDVIVVTKKDGDWWTGTVGETSGVFPSNYVRLKDSEGSGTAGKTGSLGKKPEIAQVIASYTATGPEQLTLAPGQLILIRKKNPGGWWEGELQARGKKRQIGWFPANYVKLLSPGTSKITPTELPKTAVQPAVCQVIGMYDYTAQNDDELAFSKGQIINVLSKEDPDWWKGEVSGQVGLFPSNYVKLTTDMDPSQQWCSDLHLLDMLTPTERKRQGYIHELIVTEENYVNDLQLVTEIFQKPLTESELLTEKEVAMIFVNWKELIMCNIKLLKALRVRKKMSGEKMPVKMIGDILSAQLPHMQPYIRFCSCQLNGAALIQQKTDEAPDFKEFVKRLAMDPRCKGMPLSSFILKPMQRVTRYPLIIKNILENTPENHPDHSHLKHALEKAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLSEQLVFNSVTNCLGPRKFLHSGKLYKAKSNKELYGFLFNDFLLLTQITKPLGSSSTDKVFSPKSNLQYKMYKTPIFLNEVLVKLPTDPSGDEPIFHISHIDRVYTLRAESINERTAWVQKIKAASELYIETEKKKREKAYLVRSQRATGIGRLMVNVVEGIELKPCRSHGKSNPYCEVTMGSQCHITKTIQDTLNPKWNSNCQFFIRDLEQEVLCITVFERDQFSPDDFLGRTEIRVADIKKDQGSKGPVTKCLLLHEVPTGEIVVRLDLQLFDEP", "output": "Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery. Acts as guanine nucleotide exchange factor (GEF) for CDC42, and thereby stimulates actin nucleation mediated by WASL and the ARP2/3 complex (By similarity). Plays a role in the assembly and maturation of clathrin-coated vesicles . Recruits FCHSD2 to clathrin-coated pits (By similarity). Involved in endocytosis of activated EGFR, and probably also other growth factor receptors (By similarity). Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR may involve association with DAB2 (By similarity). Promotes ubiquitination and subsequent degradation of EGFR, and thereby contributes to the down-regulation of EGFR-dependent signaling pathways. In chromaffin cells, required for normal exocytosis of catecholamines (By similarity). Required for rapid replenishment of release-ready synaptic vesicles at presynaptic active zones . Inhibits ARHGAP31 activity toward RAC1 (By similarity).; "}]}
+{"id": "function_test_373", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MMAQFPTAMNGGPNMWAITSEERTKHDKQFDNLKPSGGYITGDQARTFFLQSGLPAPVLAEIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFSPLISARFGMGSMPNLSIHQPLPPVAPIATPLSSATSGTSIPPLMMPAPLVPSVSTSSLPNGTASLIQPLSIPYSSSTLPHASSYSLMMGGFGGASIQKAQSLIDLGSSSSTSSTASLSGNSPKTGTSEWAVPQPSRLKYRQKFNSLDKGMSGYLSGFQARNALLQSNLSQTQLATIWTLADIDGDGQLKAEEFILAMHLTDMAKAGQPLPLTLPPELVPPSFRGGKQVDSVNGTLPSYQKTQEEEPQKKLPVTFEDKRKANYERGNMELEKRRQVLMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRKEIERREAAKQELERQRRLEWERLRRQELLSQKTREQEDIVRLSSRKKSLHLELEAVNGKHQQISGRLQDVQIRKQTQKTELEVLDKQCDLEIMEIKQLQQELKEYQNKLIYLVPEKQLLNERIKNMQLSNTPDSGISLLHKKSSEKEELCQRLKEQLDALEKETASKLSEMDSFNNQLKELRESYNTQQLALEQLHKIKRDKLKEIERKRLEQIQKKKLEDEAARKAKQGKENLWRESIRKEEEEKQKRLQEEKSQDKTQEEERKAEAKQSETASALVNYRALYPFEARNHDEMSFSSGDIIQVDEKTVGEPGWLYGSFQGKFGWFPCNYVEKVLSSEKALSPKKALLPPTVSLSATSTSSQPPASVTDYHNVSFSNLTVNTTWQQKSAFTRTVSPGSVSPIHGQGQAVENLKAQALCSWTAKKENHLNFSKHDVITVLEQQENWWFGEVHGGRGWFPKSYVKLIPGNEVQRGEPEALYAAVTKKPTSTAYPVTSTAYPVGEDYIALYSYSSVEPGDLTFTEGEEILVTQKDGEWWTGSIGERTGIFPSNYVRPKDQENFGNASKSGASNKKPEIAQVTSAYAASGTEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVKLLGPSSERTMPTFHAVCQVIAMYDYMANNEDELNFSKGQLINVMNKDDPDWWQGETNGLTGLFPSNYVKMTTDSDPSQQWCADLQALDTMQPTERKRQGYIHELIQTEERYMDDDLQLVIEVFQKRMAEEGFLTEADMALIFVNWKELIMSNTKLLRALRVRKKTGGEKMPVQMIGDILAAELSHMQAYIRFCSCQLNGATLLQQKTDEDTDFKEFLKKLASDPRCKGMPLSSFLLKPMQRITRYPLLIRSILENTPQSHVDHSSLKLALERAEELCSQVNEGVREKENSDRLEWIQAHVQCEGLAEQLIFNSLTNCLGPRKLLHSGKLYKTKSNKELHAFLFNDFLLLTYLVRQFAAASGHEKLFNSKSSAQFRMYKTPIFLNEVLVKLPTDPSGDEPVFHISHIDRVYTLRTDNINERTAWVQKIKGASEQYIDTEKKKREKAYQARSQKTSGIGRLMVHVIEATELKACKPNGKSNPYCEVSMGSQSYTTRTLQDTLNPKWNFNCQFFIKDLYQDVLCLTMFDRDQFSPDDFLGRTEVPVAKIRTEQESKGPTTRRLLLHEVPTGEVWVRFDLQLFEQKTLL", "output": "Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR). Plays a role in dendrite formation by melanocytes."}]}
+{"id": "function_test_374", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MWKIGQRGVPYFQRLIAAPFTTLRSLPTSLVETGQNRVIDASLTLIRERAKLKGELVRLIGGAKATTALLGVPLGHNSSFLEGPALAPPHVREAIWCGSTNSTTEEGKELKDPRVLSDVGDIPVQEIREMGVDDDRLMKVVSESVKLVMEEEPLRPLVIGGDHSISYPVVRAVSEKLGGPVDILHLDAHPDIYDRFEGNYYSHASSFARIMEGGYARRLLQVGIRSINKEGREQGKRFGVEQYEMRTFSKDRQMLENLKLGEGVKGVYISIDVDCLDPGFAHGVSHFEPGGLSFRDVLNILHNLQGDLVGADVVEYNPQRDTADDMTAMVAAKFVRELAAKMSK", "output": "Catalyzes the hydrolysis of L-arginine to urea and L-ornithine. The latter can be utilized in the urea cycle or as a precursor for the synthesis of both polyamines and proline (By similarity). Possesses agmatinase activity. Catalyzes the formation of putrescine from agmatine ."}]}
+{"id": "function_test_375", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MADEDLIFCLEGVDGGRCSRAGHNADSDTDSDDDEGYFICPITDDHMSNQNVSSKVQSYYSNLTKTECGSTGSPASSFHFKEAWKHAIEKAKHMPDPWAEFHLEDIATEHATRHRYNAVTGEWLKDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQWKGASNYVAKRYIEPVDRSVYFEDVQLQMEAKLWGEDYNRHKPPKQVDIMQMCIIELKDRPGQPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQGVGDLYTDPQIHTEKGTDFGDGNLGVRGMALFFYSHACNRICQSMGLTPFDLSPREQDAVNQSTRLLQSAKTILRGTEEKCGSPRIRTLSSSRPPLLLRLSENSGDENMSDVTFDSLPSSPSSATPHSQKLDHLHWPVFGDLDNMGPRDHDRMDNHRDSENSGDSGYPSEKRSDLDDPEPREHGHSNGNRRHESDEDSLGSSGRVCVETWNLLNPSRLHLPRPSAVALEVQRLNALDLGRKIGKSVLGKVHLAMVRYHEGGRFCEKDEEWDRESAIFHLEHAADLGELEAIVGLGLMYSQLPHHILADVSLKETEENKTKGFDYLLKAAEAGDRHSMILVARAFDTGLNLSPDRCQDWSEALHWYNTALETTDCDEGGEYDGIQDEPQYALLAREAEMLLTGGFGLDKNPQRSGDLYTQAAEAAMEAMKGRLANQYYEKAEEAWAQMEE", "output": "Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced."}]}
+{"id": "function_test_376", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDVSNTMLLVAVVAAYWLWFQRISRWLKGPRVWPVLGSLPGLIEQRDRMHDWITENLRACGGTYQTCICAVPFLAKKQGLVTVTCDPKNIEHMLKTRFDNYPKGPTWQAVFHDFLGQGIFNSDGDTWLFQRKTAALEFTTRTLRQAMGRWVNRGIKLRFCPILETAQNNYEPVDLQDLILRLTFDNICGLAFGKDTRTCAPGLPENGFASAFDRATEASLQRFILPEFLWRLKKWLGLGLEVSLSRSLGEIDGYLDAVINTRKQELLSQRESGVQRHDDLLSRFMKKKDQSYSETFLRHVALNFILAGRDTSSVALSWFFWLITTHPTVEDKIVREICSVLIETRGTDVSSWTAEPLEFDEVDRLVYLKAALSETLRLYPSVPEDSKHVVNDDILPDGTFVPAGSSVTYSIYAAGRMKSTWGEDCLEFKPERWISPDDGKFVNHDQYRFVAFNAGPRICLGKDLAYLQMKTIAAAVLLRHRLTVAPGHKVEQKMSLTLFMKNGLLVNVHKRDLEVMMKSLVPKERNDVVVLNGKCNGGIGEGVAVNAAVAVAV", "output": "Catalyzes the omega-hydroxylation of various fatty acids (FA). Acts on saturated and unsaturated fatty acids with chain lengths from C12 to C18. Plays a major role in the biosynthesis of extracellular lipids. Involved in the biosynthesis of hydroxylated fatty acids required for cutin biosynthesis, cuticle development and repression of bacterial type III gene expression."}]}
+{"id": "function_test_377", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAKKDEHLRKPEWLKIKLNTNENYTGLKKLMRENNLHTVCEEAKCPNIHECWAVRRTATFMILGSVCTRACRFCAVKTGLPTELDLQEPERVADSVALMNLKHAVITAVARDDQKDGGAGIFAETVRAIRRKSPFTTIEVLPSDMGGNYDNLKTLMDTRPDILNHNIETVRRLTPRVRARATYDRSLEFLRRAKEMQPDIPTKSSIMIGLGETKEEIIEVMDDLLANNVDIMAIGQYLQPTKKHLKVQKYYHPDEFAELKEIAMQKGFSHCEAGPLVRSSYHADEQVNEASKKRQAQA", "output": "Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives."}]}
+{"id": "function_test_378", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MADGDSGSERGGGGGGGGGPGGFQPAPRGGGGGGGGPGGEQETQELASKRLDIQNKRFYLDVKQNAKGRFLKIAEVGAGGSKSRLTLSMAVAAEFRDSLGDFIEHYAQLGPSSPEQLAAGAEEGGGPRRALKSEFLVRENRKYYLDLKENQRGRFLRIRQTVNRGGGGFGGGPGPGGLQSGQTIALPAQGLIEFRDALAKLIDDYGGDEDELAGGPGGGAGGPGGGLYGELPEGTSITVDSKRFFFDVGCNKYGVFLRVSEVKPSYRNAITVPFKAWGKFGGAFCRYADEMKEIQERQRDKLYERRGGGSGGGDESEGEEVDED", "output": "Has capacity to bind repeated elements in single-stranded DNA such as the purine-rich single strand of the PUR element located upstream of the MYC gene. Participates in transcriptional and translational regulation of alpha-MHC expression in cardiac myocytes by binding to the purine-rich negative regulatory (PNR) element. Modulates constitutive liver galectin-3 gene transcription by binding to its promoter. May play a role in the dendritic transport of a subset of mRNAs (By similarity). Plays a role in the control of vascular smooth muscle (VSM) alpha-actin gene transcription as repressor in myoblasts and fibroblasts."}]}
+{"id": "function_test_379", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSKSPDGGISEIETEEEPENLANSLDDSWRGVSMEAIHRNRQPFELENLPPVTAGNLHRVMYQLPIRETPPRPYKSPGKWDSEHVRLPCAPESKYPRENPDGSTTIDFRWEMIERALLQPIKTCEELQAAIISYNTTYRDQWHFRALHQLLDEELDESETRVFFEDLLPRIIRLALRLPDLIQSPVPLLKHHKNASLSLSQQQISCLLANAFLCTFPRRNTLKRKSEYSTFPDINFNRLYQSTGPAVLEKLKCIMHYFRRVCPTERDASNVPTGVVTFVRRSGLPEHLIDWSQSAAPLGDVPLHVDAEGTIEDEGIGLLQVDFANKYLGGGVLGHGCVQEEIRFVICPELLVGKLFTECLRPFEALVMLGAERYSNYTGYAGSFEWSGNFEDSTPRDSSGRRQTAIVAIDALHFAQSHHQYREDLMERELNKAYIGFVHWMVTPPPGVATGNWGCGAFGGDSYLKALLQLMVCAQLGRPLAYYTFGNVEFRDDFHEMWLLFRNDGTTVQQLWSILRSYSRLIKEKSSKEPRENKASKKKLYDFIKEELKKVRDVPGEGASAEAGSSRVAGLGEGKSETSAKSSPELNKQPARPQITITQQSTDLLPAQLSQDNSNSSEDQALLMLSDDEEANAMMEAASLEAKSSVEISNSSTTSKTSSTATKSMGSGGRQLSLLEMLDTHYEKGSASKRPRKSPNCSKAEGSAKSRKEIDVTDKDEKDDIVD", "output": "Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. Poly(ADP-ribose) metabolism is required for maintenance of the normal function of neuronal cells."}]}
+{"id": "function_test_380", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAPSQLAWLLRLAAFFHLCTLLAGQHLGMTKCNITCHKMTSPIPVTLLIHYQLNQESCGKRAIILETRQHRHFCADPKEKWVQDAMKHLDHQTAALTRNGGKFEKRVDNVTPRITSATRGLSPTALAKPESATVEDLTLEPTAISQEARRPMGTSQEPPAAVTGSSPSTSKAQDAGLAAKPQSTGISEVAAVSTTIWPSSAVYQSGSSLWAEEKATESPPTIALSTQASTTSSPKQNVGSEGQPPWVQEQDSTPEKSPGPEETNPVHTDIFQDRGPGSTVHPSVAPTSSEKTPSPELVASGSQAPKVEEPIHATADPQKLSVFITPVPDSQAATRRQAVGLLAFLGLLFCLGVAMFAYQSLQGCPRKMAGEMVEGLRYVPRSCGSNSYVLVPV", "output": "Chemokine that acts as a ligand for both CX3CR1 and integrins ITGAV:ITGB3 and ITGA4:ITGB1. The CX3CR1-CX3CL1 signaling exerts distinct functions in different tissue compartments, such as immune response, inflammation, cell adhesion and chemotaxis. Regulates leukocyte adhesion and migration processes at the endothelium. Can activate integrins in both a CX3CR1-dependent and CX3CR1-independent manner. In the presence of CX3CR1, activates integrins by binding to the classical ligand-binding site (site 1) in integrins. In the absence of CX3CR1, binds to a second site (site 2) in integrins which is distinct from site 1 and enhances the binding of other integrin ligands to site 1.; "}]}
+{"id": "function_test_381", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAPRRQRSGSGRRVLNEAKKVDNGNKATEDDSPPGKKMRTCQRKGPMAGGKDADRTKDNRDSVKTLLLKGKAPVDPECAAKLGKAHVYCEGDDVYDVMLNQTNLQFNNNKYYLIQLLEDDAQRNFSVWMRWGRVGKTGQHSLVTCSGDLNKAKEIFQKKFLDKTKNNWEDRENFEKVPGKYDMLQMDYAASTQDESKTKEEETLKPESQLDLRVQELLKLICNVQTMEEMMIEMKYDTKRAPLGKLTVAQIKAGYQSLKKIEDCIRAGQHGRALVEACNEFYTRIPHDFGLSIPPVIRTEKELSDKVKLLEALGDIEIALKLVKSERQGLEHPLDQHYRNLHCALRPLDHESNEFKVISQYLQSTHAPTHKDYTMTLLDVFEVEKEGEKEAFREDLPNRMLLWHGSRLSNWVGILSHGLRVAPPEAPITGYMFGKGIYFADMSSKSANYCFASRLKNTGLLLLSEVALGQCNELLEANPKAQGLLRGKHSTKGMGKMAPSPAHFITLNGSTVPLGPASDTGILNPEGYTLNYNEFIVYSPNQVRMRYLLKIQFNFLQLW", "output": "Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair . Mediates glutamate, aspartate or serine ADP-ribosylation of proteins: the ADP-D-ribosyl group of NAD(+) is transferred to the acceptor carboxyl group of target residues and further ADP-ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units . Serine ADP-ribosylation of proteins constitutes the primary form of ADP-ribosylation of proteins in response to DNA damage (By similarity). Mediates glutamate and aspartate ADP-ribosylation of target proteins in absence of HPF1 (By similarity). Following interaction with HPF1, catalyzes serine ADP-ribosylation of target proteins; HPF1 conferring serine specificity by completing the PARP2 active site (By similarity). PARP2 initiates the repair of double-strand DNA breaks: recognizes and binds DNA breaks within chromatin and recruits HPF1, licensing serine ADP-ribosylation of target proteins, such as histones, thereby promoting decompaction of chromatin and the recruitment of repair factors leading to the reparation of DNA strand breaks (By similarity). HPF1 initiates serine ADP-ribosylation but restricts the polymerase activity of PARP2 in order to limit the length of poly-ADP-ribose chains (By similarity). Specifically mediates formation of branched poly-ADP-ribosylation (By similarity). Branched poly-ADP-ribose chains are specifically recognized by some factors, such as APLF (By similarity). In addition to proteins, also able to ADP-ribosylate DNA: preferentially acts on 5'-terminal phosphates at DNA strand breaks termini in nicked duplex (By similarity)."}]}
+{"id": "function_test_382", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKLITILLLCSRLLPSLAQEEGAQELNCNDETVFQAVDTALKKYNAELESGNQFVLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALREVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPSLREDCVPLPYGDHGECTGHTHVDIHNTIAGFSQSCDLYPGDDLFELLPKNCRGCPREIPVDSPELKEALGHSIAQLNAQHNHIFYFKIDTVKKATSQVVAGVIYVIEFIARETNCSKQSKTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVRVQETKEGTTRLLNSCEYKGRLSKARAGPAPDHQAEASTVTP", "output": "Kininogens are plasma glycoproteins with a number of functions: (1) as precursor of the active peptide bradykinin they effect smooth muscle contraction, induction of hypotension and increase of vascular permeability. (2) They play a role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII. (3) They are inhibitor of thiol proteases."}]}
+{"id": "function_test_383", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPWGRRPTWLLLAFLLVFLKISILSVTAWQTGNCQPGPLERSERSGTCAGPAPFLVFSQGKSISRIDPDGTNHQQLVVDAGISADMDIHYKKERLYWVDVERQVLLRVFLNGTGLEKVCNVERKVSGLAIDWIDDEVLWVDQQNGVITVTDMTGKNSRVLLSSLKHPSNIAVDPIERLMFWSSEVTGSLHRAHLKGVDVKTLLETGGISVLTLDVLDKRLFWVQDSGEGSHAYIHSCDYEGGSVRLIRHQARHSLSSMAFFGDRIFYSVLKSKAIWIANKHTGKDTVRINLHPSFVTPGKLMVVHPRAQPRTEDAAKDPDPELLKQRGRPCRFGLCERDPKSHSSACAEGYTLSRDRKYCEDVNECATQNHGCTLGCENTPGSYHCTCPTGFVLLPDGKQCHELVSCPGNVSKCSHGCVLTSDGPRCICPAGSVLGRDGKTCTGCSSPDNGGCSQICLPLRPGSWECDCFPGYDLQSDRKSCAASGPQPLLLFANSQDIRHMHFDGTDYKVLLSRQMGMVFALDYDPVESKIYFAQTALKWIERANMDGSQRERLITEGVDTLEGLALDWIGRRIYWTDSGKSVVGGSDLSGKHHRIIIQERISRPRGIAVHPRARRLFWTDVGMSPRIESASLQGSDRVLIASSNLLEPSGITIDYLTDTLYWCDTKRSVIEMANLDGSKRRRLIQNDVGHPFSLAVFEDHLWVSDWAIPSVIRVNKRTGQNRVRLQGSMLKPSSLVVVHPLAKPGADPCLYRNGGCEHICQESLGTARCLCREGFVKAWDGKMCLPQDYPILSGENADLSKEVTSLSNSTQAEVPDDDGTESSTLVAEIMVSGMNYEDDCGPGGCGSHARCVSDGETAECQCLKGFARDGNLCSDIDECVLARSDCPSTSSRCINTEGGYVCRCSEGYEGDGISCFDIDECQRGAHNCGENAACTNTEGGYNCTCAGRPSSPGLSCPDSTAPSLLGEDGHHLDRNSYPGCPSSYDGYCLNGGVCMHIESLDSYTCNCVIGYSGDRCQTRDLRWWELRHAGYGQKHDIMVVAVCMVALVLLLVLGMWGTYYYRTRKQLSNPPKNPCDEPSGSVSSSGPNSSSGAAVASCPQPWFVVLEKHQDPKNGSLPADGTNGAVVDAGLSPSLQLGSVHLTSWRQKPHIDGMGTGQSCWIPPSSDRGPQEIEGNSHLPSYRPVGPEKLHSLQSANGSCHERAPDLPRQTEPVQ", "output": "EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity)."}]}
+{"id": "function_test_384", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAELGKGSFKYAWVLDKLKAERERGITIDIALWKFETPKYQVTVIDAPGHRDFIKNMITGTSQADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLEAIDAIEQPSRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVIKPGMVVTFAPAGVTTEVKSVEMHHEQLEQGVPGDNVGFNVKNVSVKEIRRGNVCGDAKNDPPKGCASFNATVIVLNHPGQISAGYSPVLDCHTAHIACRFDELLEKNDRRSGKKLEDHPKFLKSGDAALVKFVPSKPMCVEAFSEYPPLGRFAVRDMRQTVAVGVIKSVDKTEKAAKVTKAAQKAAKK", "output": "GTP-binding component of the eukaryotic elongation factor 1 complex (eEF1). In its active GTP-bound form, binds to and delivers aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. In the presence of a correct codon-anticodon match between the aminoacyl-tRNA and the A-site codon of the ribosome-bound mRNA, the ribosome acts as a GTPase activator and the GTP is hydrolyzed. The inactive GDP-bound form leaves the ribosome and must be recycled by its guanine nucleotide exchange factor (GEF) (eEF1B subcomplex) before binding another molecule of aminoacyl-tRNA. Required for nuclear export of aminoacyl-tRNAs. May also be involved in translational quality control by targeting cotranslationally damaged proteins to the proteasome. Also exhibits actin filament-binding and -bundling activities and is involved in cytoskeleton organization. Plays a role as a negative regulator of GCN2 kinase activity by inhibiting GCN2-mediated eIF-2-alpha phosphorylation in amino acid-repleted cells ."}]}
+{"id": "function_test_385", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MALEEVVRYLGPHNEIPLTLTRDSETGHFLLKHFLPILQQYHDTGNINETNPDSFPTDEERNKLLAHYGIAVNTDDRGELWIELEKCLQLLNMLNLFGLFQDAFEFEEPETDQDEEDPSHSKLPENKTKSENSKDNISSKRINNLQDMSLDSDAHRELGSPLKKLKIDTSVIDAESDSTPNTARGKPNDDINKGPSGDNENNGTDDNDRTAGPIITFTHDLTSDFLSSPLKIMKALPSPVVNDNEQKMKLEAFLQRLLFPEIQEMPTSLNNDSSNRNSEGGSSNQQQQHVSFDSLLQEVNDAFPNTQLNLNIPVDEHGNTPLHWLTSIANLELVKHLVKHGSNRLYGDNMGESCLVKAVKSVNNYDSGTFEALLDYLYPCLILEDSMNRTILHHIIITSGMTGCSAAAKYYLDILMGWIVKKQNRPIQSGTNEKESKPNDKNGERKDSILENLDLKWIIANMLNAQDSNGDTCLNIAARLGNISIVDALLDYGADPFIANKSGLRPVDFGAGTSKLQNTNGGDENSKMVSKGDYDGQKNGKAKKIRSQLLKNPPETTSLINDVQNLLNSISKDYENETVQYNEKLEKLHKELNEQREELANSREQLANVKQLKDEYSLMQEQLTNLKAGIEEEEESFREESKKLGIIADESSGIDWDSSEYDADEPFKVEFLSDFLEDKLQKNYEGDISKLLEAESKEQIMEQIRNQLPAEKIQSMLPPTVLLKARINAYKRNDKHLTNVLDTISTKQSELENKFRRVLSLCLKIDENKVDNMLDGLLQAISSEDPQDIDTDEMQDFLKKHAS", "output": "Part of a complex involved in cell-cycle-dependent transcription. SWI4 and SWI6 are required for formation of the cell-cycle box factor-DNA complex. The repeated element in the upstream region of HO (5'-CACGAAAA-3') is called the cell cycle box (CCB)."}]}
+{"id": "function_test_386", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPTIAVHQSDEQLALMDDWNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVPAGKSPICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQAMDDIRESVAELAYYREHFIKL", "output": "3'-to-5' exoribonuclease specific for small oligoribonucleotides 2 to 5 nucleotides in length, as well as small (2 to 5 nucleotides) ssDNA oligomers. Probably responsible for the final step in mRNA degradation."}]}
+{"id": "function_test_387", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKYQQLENLESGWKWKYLVKKHREGELITRYIEASAAQEAVDVLLSLENEPVLVNGWIDKHMNPELVNRMKQTIRARRKRHFNAEHQHTRKKSIDLEFIVWQRLAGLAQRRGKTLSETIVQLIEDAENKEKYANKMSSLKQDLQALLGKE", "output": "Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain."}]}
+{"id": "function_test_388", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSLINTKIKPFKNQAFKNGEFIEITEKDTEGRWSVFFFYPADFTFVCPTELGDVADHYEELQKLGVDVYAVSTDTHFTHKAWHSSSETIAKIKYAMIGDPTGALTRNFDNMREDEGLADRATFVVDPQGIIQAIEVTAEGIGRDASDLLRKIKAAQYVASHPGEVCPAKWKEGEATLAPSLDLVGKI", "output": "Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Is the primary scavenger for endogenously generated hydrogen peroxides."}]}
+{"id": "function_test_389", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MASSYFLFLCLLLCGGPELCNSQTLWLLPGGTPTPVGSSSPVKVECLEAELVVTVSRDLFGTGKLVQPGDLTLGSEGCQPRVSVDTDVVRFNAQLHECSSRVQMTKDALVYSTFLLHDPRPVSGLSILRTNRVEVPIECRYPRQGNVSSHPIQPTWVPFRATVSSEEKLAFSLRLMEENWNTEKSAPTFHLGEVAHLQAEVQTGSHLPLQLFVDHCVATPSPLPDPNSSPYHFIVDFHGCLVDGLSESFSAFQVPRPRPETLQFTVDVFHFANSSRNTLYITCHLKVAPANQIPDKLNKACSFNKTSQSWLPVEGDADICDCCSHGNCSNSSSSQFQIHGPRQWSKLVSRNRRHVTDEADVTVGPLIFLGKANDQTVEGWTASAQTSVALGLGLATVAFLTLAAIVLAVTRKCHSSSYLVSLPQ", "output": "Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation."}]}
+{"id": "function_test_390", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MANPTTGKSSIRAKLSNSSLSNLFKKNKNKRQREETEEQDNEDKDESKNQDENKDTQLTPRKRRRLTKEFEEKEARYTNELPKELRKYRPKGFRFNLPPTDRPIRIYADGVFDLFHLGHMKQLEQCKKAFPNVTLIVGVPSDKITHKLKGLTVLTDKQRCETLTHCRWVDEVVPNAPWCVTPEFLLEHKIDYVAHDDIPYVSADSDDIYKPIKEMGKFLTTQRTNGVSTSDIITKIIRDYDKYLMRNFARGATRQELNVSWLKKNELEFKKHINEFRSYFKKNQTNLNNASRDLYFEVREILLKKTLGKKLYSKLIGNELKKQNQRQRKQNFLDDPFTRKLIREASPATEFANEFTGENSTAKSPDDNGNLFSQEDDEDTNSNNTNTNSDSDSNTNSTPPSEDDDDNDRLTLENLTQKKKQSAN", "output": "Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis."}]}
+{"id": "function_test_391", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MYSMQLASCVALTLVLLVNSAPTSSPAKETQQHLEQLLLDLQVLLRGIDNYKNLKLPMMLTFKFYLPKQATELKHLQCLENELGALQRVLDLTQSKSFHLEDAGNFISNIRVTVVKLKGSENKFECQFDDEPATVVEFLRRWIAICQSIISTMTQ", "output": "Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance. Binds to a receptor complex composed of either the high-affinity trimeric IL-2R (IL2RA/CD25, IL2RB/CD122 and IL2RG/CD132) or the low-affinity dimeric IL-2R (IL2RB and IL2RG). Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3. In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5. This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways. Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well. Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production. Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance. Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells."}]}
+{"id": "function_test_392", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MVSQETIKHVKDLIAENEIFVASKTYCPYCHAALNTLFEKLKVPRSKVLVLQLNDMKEGADIQAALYEINGQRTVPNIYINGKHIGGNDDLQELRETGELEELLEPILAN", "output": "Component of the glutathione system which performs several activities such as glutathione-dependent oxidoreductase, glutathione peroxidase and glutathione S-transferase (GST) activity . The disulfide bond functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase. In addition, it is also involved in reducing cytosolic protein- and non-protein-disulfides in a coupled system with glutathione reductase. Required for resistance to reactive oxygen species (ROS) by directly reducing hydroperoxides and for the detoxification of ROS-mediated damage. GRX1 is less active as an oxidoreductase than GRX2 ."}]}
+{"id": "function_test_393", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MASEEGQVIACHTVETWNEQLQKANESKTLVVVDFTASWCGPCRFIAPFFADLAKKLPNVLFLKVDTDELKSVASDWAIQAMPTFMFLKEGKILDKVVGAKKDELQSTIAKHLA", "output": "Thiol-disulfide oxidoreductase involved in the redox regulation of a number of cytosolic enzymes. Activates the cytosolic malate dehydrogenase (MDH) probably by reducing an interchain disulfide bond of the inactive MDH homodimer. Possesses insulin disulfide bonds reducing activity."}]}
+{"id": "function_test_394", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNSTPDLISPQKSSENSNADLPSNSSQVMNMPEEKGVQDDFQAEADQVLTNPNTGKGAYVTVSICCVMVAFGGFVFGWDTGTISGFVAQTDFLRRFGMKHKDGSYYLSKVRTGLIVSIFNIGCAIGGIILAKLGDMYGRKMGLIVVVVIYIIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVAPKEMRGTLVSCYQLMITLGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLVEAGQIDEARASLSKVNKVAPDHPFIQQELEVIEASVEEARAAGSASWGELFTGKPAMFKRTMMGIMIQSLQQLTGDNYFFYYGTTVFNAVGMSDSFETSIVFGVVNFFSTCCSLYTVDRFGRRNCLLYGAIGMVCCYVVYASVGVTRLWPNGEGNGSSKGAGNCMIVFACFYIFCFATTWAPIAYVVISETFPLRVKSKAMSIATAANWLWGFLIGFFTPFITGAINFYYGYVFMGCMVFAYFYVFFFVPETKGLTLEEVNDMYAEGVLPWKSASWVPTSQRGANYDADALMHDDQPFYKKMFGKK", "output": "Low-affinity glucose transporter."}]}
+{"id": "function_test_395", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSRVISRSTPGGTCIVSKDDFLKSFEEVPKMEISSPSDFKEKLDQTIETLSKGQEDWNKRMNKLKQIRSMVVHGEDVIGREQLLSQLVRLTDCLDLSVKDLRSQILREAAITCGFLFKRFGTDVRQIAERCLPSAFAQVAVSTKVMATCGAVLTLFIVEFIQTKQIFTCIASYSTSKDKNQRRQLCALLEIVLEHWNEKIKRTVLPQIGELIKAAICDADPETRVAGRKAFSKLDALHSTEADKLFASVDSSKQKMLRASDAASSSTSINSERGTAPFRSKLSAGSIGGIRNAPNISSKFLAQRSASAIDTKQVTRMATSVSRTPNIRPMTTRTLSKIDTSPGGSKFARPTVGALGSRTSSNLRARGSVPTSQPGSRNGSPPRRPSATEAFPAEMQRVKSNLGSNSFVSSLSAEEATKLQKAMNTAKESLRQPSRNDDDEFLLPKRPTPQKATPQKSALDTSRVEEVIRACSSTSANEKREGIKMLAGIVSEPNLSNAEIKSLGAVLNRLLGESTNQIVLESISSFVKTHHPRLSDWLKLGLGKLFAKKGAEMTLNSKKQISTTISCILSSFDPTLQLKSTCELVCDPIHLMSPKSRVVLLEYLNELLGKYMERGSSFNTKEMKATILKMFSWMADQRNEQLITPHGEKVLCSLFALNNADFSALFNDFNPDYRDWAYKVLQSHGHDQHVPQQDAVSEEACVRATISTTAAQIEDFVVSRNLDMTPVKSPSTRAISSGFKRVDAEPLRPLSSEMNSQHRDEELSFNESFDRLKLNSTTHLIDDTSEQSKYVASKLAQISGDMGAQQYEGLLSIQTMLCEGSFTLWEQNFAKLLIAVFDVLSKSESDANKKVALRVLTKMCTSQASRLFDSTEMAICKVLDAAVNSQDGTMNVTADDCLKTLATHLPLAKVVNISQLILNEEKAQEPKASLVLKMMTRLFEGLQADELSPVVDDLAPCVIKSYDSPSSAVRKTAVYCLVAMVNKLGMKTMEPHLQNLSSGKLNLVQVYVNRAMSSSSHSHV", "output": "Probable microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Required for the formation of mitotic and meiotic spindles. Specifically promotes the polymerization of kinetochore-bound microtubules. Also required for cytoplasmic streaming. Essential for embryonic development."}]}
+{"id": "function_test_396", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "KGKTITHGQSWGARRIHSHFYITIFTITCIRIGQYKLALYLDPYRFYNITGSQIVRLKGQRPEYRKRIFAHSYRHSSRIGLNFPSRRRYSNYVDRGNIHKHTRLPPQFIGLNTVESAQPSILRDFVDLRGGHTVISKILIANNGIAAVKEMRSIRKWAYETFNDEKIIQFVVMATPDDLHANSEYIRMADQYVQVPGGTNNNNYANIDLILDVAEQTDVDAVWAGWGHASENPCLPELLASSQRKILFIGPPGRAMRSLGDKISSTIVAQSAKIPCIPWSGSHIDTIHIDNKTNFVSVPDDVYVRGCCSSPEDALEKAKLIGFPVMIKASEGGGGKGIRRVDNEDDFIALYRQAVNETPGSPMFVMKVVTDARHLEVQLLADQYGTNITLFGRDCSIQRRHQKIIEEAPVTITKPETFQRMERAAIRLGELVGYVSAGTVEYLYSPKDDKFYFLELNPRLQVEHPTTEMISGVNLPATQLQIAMGIPMHMISDIRKLYGLDPTGTSYIDFKNLKRPSPKGHCISCRITSEDPNEGFKPSTGKIHELNFRSSSNVWGYFSVGNNGAIHSFSDSQFGHIFAVGNDRQDAKQNMVLALKDFSIRGEFKTPIEYLIELLETRDFESNNISTGWLDDLILKNLSSDSKLDPTLAIICGAAMKAYVFTEKVRNKYLELLRRGQVPPKDFLKTKFPVDFIFDNNRYLFNVAQSSEEQFILSINKSQCEVNVQKLSSDCLLISVDGKCHTVYWKDDIRGTRLSIDSNTIFLEAELNPTQVISPTPGKLVKYLVRSGDHVFAGQQYAEIEIMKMQMPLVAKSDGVIELLRQPGSIIEAGDVIAKLTLDSPSKANESSLYRGELPVLGPPLIEGSRPNHKLRVLINRLENILNGYHENSGIETTLKELIKILRDGRLPYSEWDSQISTVRNRLPRQLNEGLGNLVKKSVSFPAKELHKLMKRYLEENTNDHVVYVALQPLLKISERYSEGLANHECEIFLKLIKKYYAVEKIFENHDIHEERNLLNLRRKDLTNLKKILCISLSHANVVAKNKLVTAILHEYEPLCQDSSKMSLKFRAVIHDLASLESKWAKEVAVKARSVLLRGIFPPIKKRKEHIKTLLQLHIKDTGAENIHSRNIYSCMRDFGNLIHSNLIQLQDLFFFFGHQDTALSSIASEIYARYAYGNYQLKSIKIHKGAPDLLMSWQFSSLRNYLVNSDGESDEFTKLSKPPSTSGKSSANSFGLLVNMRALESLEKTLDEVYEQIHIPEERLSSGENSLIVNILSPIRYRSENDLIKTLKIKLHENERGLSKLKVNRITFAFIAANAPAVKFYSFDGTTYDEISQIRNMDPSYEAPLELGKMSNYKIRSLPTYDSSIRIFEGISKFTPLDKRFFVRKIINSFMYNDQKTTEENLKAEINAQVVYMLEHLGAVDISNSDLNHIFLSFNTVLNIPVHRLEEIVSTILKTHETRLFQERITDVEICISVECLETKKPAPLRLLISNKSGYVVKIETYYEKIGKNGNLILEPCSEQSHYSQKSLSLPYSVKDWLQPKRYKAQFMGTTYVYDFPGLFHQAAIQQWKRYFPKHKLNDSFFSWVELIEQNGNLIKVNREPGLNNIGMVAFEIMVQTPEYPEGRNMIVISNDITYNIGSFGPREDLFFDRVTNYARERGIPRIYLAANSGAKLGIAEELIPLFRVAWNDPSDPTKGFQYLYLAPKDMQLLKDSGKGNSVVVEHKMVYGEERYIIKAIVGFEEGLGVECLQGSGLIAGATSKAYRDIFTITAVTCRSVGIGSYLVRLGQRTIQVEDKPIILTGASAINKVLGTDIYTSNLQIGGTQIMYKNGIAHLTASNDMKAIEKIMTWLSYVPAKRDMSPPLLETMDRWDRDVDFKPAKQVPYEARWLIEGKWDSNNNFQSGLFDKDSFFETLSGWAKGVIVGRARLGGIPVGVIAVETKTIEEIIPADPANLDSSEFSVKEAGQVWYPNSAFKTAQTINDFNYGEQLPLIILANWRGFSGGQRDMYNEVLKYGSFIVDALVDYKQPILIYIPPFGELRGGSWVVIDPTINPEQMEMYADVESRGGVLEPDGVVSIKYRKEKMIETMIRLDSTYGHLRRTLTEKKLSLEKQNDLTKRLKIRERQLIPIYNQISIQFADLHDRSTRMLVKGVIRNELEWKKSRRFLYWRLRRRLNEGQVIKRLQKKTCDNKTKMKYDDLLKIVQSWYNDLDVNDDRAVVEFIERNSKKIDKNIEEFEISLLIDELKKKFEDRRGNIVLEELTRLVDSKRKR", "output": "Catalyzes the rate-limiting reaction in the mitochondrial fatty acid synthesis (FAS) type II pathway. Responsible for the production of the mitochondrial malonyl-CoA, used for the biosynthesis of the cofactor lipoic acid. This protein carries three functions: biotin carboxyl carrier protein, biotin carboxylase, and carboxyltransferase."}]}
+{"id": "function_test_397", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MARRPDNQNPEGENLRIKRVRLESVRQNDEEEENEVSRTQNIVTDNRHDSPEAVVEIIGERALENTSEEDGDDDLSLFRALEEDPGSDHNTSNNDSGNHDRETMHTEEPEASSGNNITLTNNVEELHTMDVLSQTANTPSASPMLDAAPPTTKPGTNSKEQTVDLTADAIDLDAEEQQVLQISDDDFQEETKEAPKEYGAAKDYRCPICFEPPETALMTLCGHVFCCPCLFQMVNSSRTCRQFGHCALCRSKVYLKDVRLIILRKKQVKKKVKS", "output": "Component of the SUMO-targeted ubiquitin ligase (STUbL) complex SLX5/SLX8 that mediates ubiquitination and subsequent desumoylation of sumoylated proteins and proteins containing SUMO-like domains for their degradation . The STUbL complex SLX5/SLX8 stimulates ubiquitin conjugating enzymes, including UBC1, UBC4, UBC5 and UBC13-MMS2, and mediates the proteolytic down-regulation of sumoylated proteins . The STUbL complex SLX5/SLX8 is involved in ubiquitin-mediated degradation of histone variant CSE4, preventing mislocalization to euchromatin . The complex plays an essential role in maintenance of chromosome stability and links SUMO-dependent ubiquitination to a centromere-specific function during mitosis . The complex is involved in proteolysis of spindle positioning protein KAR9 and ensures correct spindle function by regulating levels of microtubule-associated proteins . During replication, the complex helps to prevent DNA lesions via recombination and has a role in localizing the DNA damage protein DCD2 . The complex especially ubiquitinates the nuclease YEN1 and prevents persistent accumulation of a fraction of YEN1 associated with sites of activity in late G2/M and helps maintain the balance between pro- and anti-crossover pathways during homologous recombination . It is also involved in ubiquitin-mediated degradation of DNA repair proteins RAD52 and RAD57 . Finally, the complex is recruited to distinct genomic hotspots of non-H2B protein ubiquitination (ub-hotspots) by the sumoylated transcription factor-like protein EUC1 where it ubiquitinates EUC1 and presumably other targets ."}]}
+{"id": "function_test_398", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKFSTAVTTLISSGAIVSALPHVDVHQEDAHQHKRAVAYKYVYETVVVDSDGHTVTPAASEVATAATSAIITTSVLAPTSSAAAADSSASIAVSSAALAKNEKISDAAASATASTSQGASSSSSSSSATSTLESSSVSSSSEEAAPTSTVVSTSSATQSSASSATKSSTSSTSPSTSTSTSTSSTSSSSSSSSSSSSSSSGSGSIYGDLADFSGPSEKFQDGTIPCDKFPSGQGVISIDWIGEGGWSGVENTDTSTGGSCKEGSYCSYSCQPGMSKTQWPSDQPSDGRSVGGLLCKNGYLYRSNTDADYLCEWGVEAAYVVSKLSKGVAICRTDYPGTENMVIPTYVEGGSSLPLTVVDQDTYFTWEGKKTSAQYYVNNAGVSVEDGCIWGTSGSGIGNWAPLNFGAGSTGGVTYLSLIPNPNNSDALNYNVKIVAADDSSNVIGECVYENGEFSGGADGCTVSVTSGKAHFVLYN", "output": "Involved in the remodeling of the cell wall during the various phases of yeast culture development and under various environmental conditions. Required for the maintenance of the CLB5 kinase activity."}]}
+{"id": "function_test_399", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNNNVEELLRRIPLYNKYGKDFPQETVTRFQMPEFKLPALQPTRDLLCPWYEECDNITKVCQLHDSSNKKFDQWYKEQYLSKKPPGIVGNTLLSPSRKDNS", "output": "Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Appears to be involved in cargo sorting and release of the ESCRT-I complex from the MVBs."}]}
+{"id": "function_test_400", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAGIKVFGHPASIATRRVLIALHEKNLDFELVHVELKDGEHKKEPFLSRNPFGQVPAFEDGDLKLFESRAITQYIAHRYENQGTNLLQTDSKNISQYAIMAIGMQVEDHQFDPVASKLAFEQIFKSIYGLTTDEAVVAEEEAKLAKVLDVYEARLKEFKYLAGETFTLTDLHHIPAIQYLLGTPTKKLFTERPRVNEWVAEITKRPASEKVQ", "output": "Binds auxin, endogenous flavonoids and the phytoalexin camalexin and may be involved in regulating the binding and transport of small bioactive natural products and defense-related compounds during plant stress. Binds a series of heterocyclic compounds, including lumichrome, harmane, norharmane and indole-3-aldehyde. In vitro, possesses glutathione S-transferase activity toward 1-chloro-2,4-dinitrobenzene (CDNB) and benzyl isothiocyanate (BITC). Acts as glutathione peroxidase on cumene hydroperoxide, linoleic acid-13-hydroperoxide and trans-stilbene oxide, but not trans-cinnamic acid or IAA-CoA."}]}
+{"id": "function_test_401", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSTAVTFFGQHVLNRVSFLRCSKEFIKKSLNHDSTVFIPFIEGEALISPENGDLVQLSNSVKSYKNILSAIVPLYTTLLNTTRSRSDESGINVTFLGLLEGTDSAFNFEWSNISYKGTPYFGLDIRVTESTLFKKVDFEPIFSYPKVTRDHIFKQTNEDASLYSQGKMYLDWLAKYKFCPGCGSPLFPVEAGTKLQCSNENRNVYCNVRDARINNVCFPRTDPTVIIALTNSDYSKCCLARSKKRYGDFVLYSTIAGFMEPSETIEEACIREIWEETGISCKNIDIVRSQPWPYPCSLMIGCLGIVQFNSKNEVINLNHDDELLDAQWFDTTEIIQALDKYAGGYRVPFKNDINLPGSTTIAFQLINHVCENYKNLRKTSSSHL", "output": "mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some RNAs; in contrast to the canonical N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay (By similarity). Mediates the hydrolysis of some nucleoside diphosphate derivatives ."}]}
+{"id": "function_test_402", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MALRRSMGRPGLRPLLLAGLASLLLPGSAAAGLKLMGAPVKMTVSQGQPVKLNCSVEGMDDPDIHWMKDGAVVQNASQVSISISEQNWIGLLSLKSAERSDAGLYWCQVKDGEETKISQSVWLTVEGVPFFTVEPKDLAVPPNVPFQLSCEAVGPPEPVTIFWWRGPTKVGGPASSPSVLNVTGVTQRTEFSCEAHNIKGLATSRPAIIRLQAPPAAPFNITVTTISSSNASVAWVPGADGLALLHSCTVQVAHAPGEWEALAVVVPVPPFTCLLRNLAPATNYSLRVRCANALGPSPYGDWVPFQTKGLAPARAPQNFHAIRTDSGLILEWEEVIPEDPGEGPLGPYKLSWVQENGTQDELMVEGTTANLTDWDPQKDLVLRVCASNAIGDGPWSQPLVVSSHDHAGRQGPPHSRTSWVPVVLGVLTALITAAALALILLRKRRKETRFGQAFDSVMARGEPAVHFRAARSFNRERPERIEATLDSLGISDELKEKLEDVLIPEQQFTLGRMLGKGEFGSVREAQLKQEDGSFVKVAVKMLKADIIASSDIEEFLREAACMKEFDHPHVAKLVGVSLRSRAKGRLPIPMVILPFMKHGDLHAFLLASRIGENPFNLPLQTLVRFMVDIACGMEYLSSRNFIHRDLAARNCMLAEDMTVCVADFGLSRKIYSGDYYRQGCASKLPVKWLALESLADNLYTVHSDVWAFGVTMWEIMTRGQTPYAGIENAEIYNYLISGNRLKQPPECMEEVYDLMYQCWSADPKQRPSFTCLRMELENILGHLSVLSTSQDPLYINIERAGQPAENGSPELPCGEQSSSEAGDGSGMGAIGGIPSDCRYIFSPGGLAESPGQLEQQPESPLNENQRLLLLQQGLLPHSSC", "output": "Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including TULP1 or GAS6. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with PIK3R1 and thereby enhances PI3-kinase activity. Activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes. TYRO3 signaling plays a role in various processes such as neuron protection from excitotoxic injury, platelet aggregation and cytoskeleton reorganization. Also plays an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3 (By similarity)."}]}
+{"id": "function_test_403", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPIVLVRPTNRTRRLDSTGAGMGPSSHQQQESPLPTITHCAGCTTAWSPCSFNSSDMETPLQFQRGFFPEQPPPPPRSSHLHCQQQQQSQDKPCAPFAPLPHPHHHPHLAHQQPGSGGSSPCLRCNSCASSGAPAAGAGAGDNLSLLLRTSSPGGAFRTRTSSPLSGSSCCCCCSSRRGSQLNVSELTPSSHASALRQQYAQQPASASQYHQCHSLQPATSPTGSLGSLGSGPPLSHHHHHPHPAHHQHHQPQARRESNPFTEIAMSSCRYNGGVMRPLSNLSSSRRNLQEMDSEAQPLQPPASVVGGGGGASSPSAAAAASSSAPEIVVSKPEHNNSNNLALYGTGGGGSTGGGGGGSGHGSSSGTKSSKKKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELSWGAYDKASLYSLALKCLISLSTIILLGLIIVYHAREIQLFMVDNGADDWRIAMTYERIFFICLEILVCAIHPIPGNYTFTWTARLAFSYAPSTTTADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRACERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPNTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSIHALPGLISQTIRQQQRDFIETQMENYDKHVSYNAERSRSSSRRRRSSSTAPPTSSESS", "output": "Forms a voltage-independent potassium channel activated by intracellular calcium . Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization."}]}
+{"id": "function_test_404", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTVTQTDLFPYGDYLNSSQLHMEPDVVDTLKEGEDPADRMHPFLAIYDLQPLRAHPLVFAPGVPVIAQVVGTERYTSGSKVGTCTLYSVRLTHGDFTWTTKKKFRHFQELHRDLQRHKVLMSLLNLARFAAAHSPAREAANENIPSLPRGGSEGSARHTASKQKYLENYLNRLLTMSFYRNYHAMTEFLEVSQLSFIPDLGSKGLEGVIRKRSGGHRVPGFTCCGRDQVCYRWSKRWLVVKDSFLLYMRPETGAISFVQLFDPGFEVQVGKRSTEARYGVRIDTSHRSLILKCSSYRQARWWGQEITELAQGPGRDFLQLHQHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAREEIFITDWWLSPEIYLKRPAHSDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSKRTLMLLHPNIKVMRHPDLVTLWAHHEKLLVVDQAVAFLGGLDLAYGRWDDVQYRLTDLGDPSESADSQTPTPGSDPAATPDLSHNHFFWLGKDYSNLITKDWVQLDRPFEDFIDRETTPRMPWRDVGVVVHGVAARDLARHFIQRWNFTKTIKARYKIPQYPYLLPKSASTANHLPFIIPGGQCATVQVLRSVDRWSAGTLESSILNAYLHTIRESQHFLYIENQFFISCSDGRTVLNKVGDEIVDRILKAHEQGQCFRVYVLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSILHRLKAAMGTAWRDYMSICGLRTHGELGGHPISELIYIHSKLLIADDRTVIIGSANINDRSLLGKRDSELAILIKDTEMEPSLMDGVEYQAGRFALSLRGRCFSVILGANTWPDLDLRDPVCDDFFQLWQETAENNATIYEQIFRCLPSNATRSLRALREYVAVESLATVSPSLAQSELAHIRGHLVHFPLKFLEDESLLPHWGAKRGMIPLEVWT", "output": "Function as phospholipase selective for phosphatidylcholine (By similarity) . May have a role in signal-induced cytoskeletal regulation and/or endocytosis (By similarity) ."}]}
+{"id": "function_test_405", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVGKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEIAALTSKLGDLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLAAQLADLAARGEGESPQARALASQLQDSLKDLKTQMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGAANKSTVEGIQASVKTARELTPQVISAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ", "output": "Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion."}]}
+{"id": "function_test_406", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKAPTALAPGILLLLLTLAQRSHGECKEALVKSEMNVNMKYQLPNFTAETPIHNVVLPGHHIYLGATNYIYVLNDKDLQKVSEFKTGPVVEHPDCFPCQDCSSKANVSGGVWKDNVNMALLVDTYYDDQLISCGSVNRGTCQRHVLPPDNAADIQSEVHCMFSPLAEEESGQCPDCVVSALGAKVLLSEKDRFINFFVGNTINSSYPPDYSLHSISVRRLKETQDGFKFLTDQSYIDVLPEFRDSYPIKYIHAFESNHFIYFLTVQKETLDAQTFHTRIIRFCSVDSGLHSYMEMPLECILTEKRRKRSTREEVFNILQAAYVSKPGANLAKQIGASPYDDILYGVFAQSKPDSAEPMNRSAVCAFPIKYVNDFFNKIVNKNNVRCLQHFYGPNHEHCFNRTLLRNSSGCEVRSDEYRTEFTTALQRVDLFMGRLNHVLLTSISTFIKGDLTIANLGTSEGRFMQVVLSRTAHFTPHVNFLLDSYPVSPEVIVEHPSNQNGYTLVVTGKKITKIPLNGLGCGHFQSCSQCLSPPYFIQCGWCHNRCVHSNECPSGTWTQEICLPAVYKVFPTSAPLEGGTMLTICGWDFGFKKNNKFDLRKTKVLLGNESCTLTLSESTTNTLKCTVGPAMSEHFNVSVIVSNSRETTQYSAFSYVDPVITSISPRYGPHAGGTLLTLTGKYLNSGNSRHISIGGKTCTLKSVSDSILECYTPGHTVSAEFPVKLKIDLADRVTSSFSYREDPVVSEIHPTKSFISGGSTITGIGKNLNSVSTPKLVIEVHDVGVNYTVACQHRSSSEIICCTTPSLRQLDLQLPLKTKAFFLLDGILSKHFDLTYVHDPMFKPFEKPVMISMGNENVVEIKGDDIDPEAVKGEVLKVGNKSCENLHWHSEALLCTVPSDLLKLNGGELNIEWKQAVSSTVLGKVIVQPDQNFAGLIIGAVSISVVVLLVSGLFLWLRKRKHKDLGSELVRYDARVHTPHLDRLVSARSVSPTTEMVSNESVDYRATFPEDQFPNSSQNGACRQVQYLLTDLSPILTSGDSDISSPLLQNTVHIDLSALNPELVQAVPHVVIGPSSLIVHFNEVIGRGHFGCVYHGTLLDSDGKKIHCAVKSLNRITDIEEVSQFLTEGIIMKDFSHPNVLSLLGICLRSEGSPLVVLPYMKHGDLRNFIRNETHNPTVKDLIGFGLQVAKGMKYLVSKKFVHRDLAARNCMLDEKFTVKVADFGLARDMYDKEYYSVHNKTGAKLPVKWMALESLQTQKFTTKSDVWSFGVLLWELMTRGAPPYPDVNTFDITIYLLQGRRLLQPEYCPDALYEVMLKCWHPKAEMRPSVSELVSRISSIFSTFIGEHYVHVNATYVNVKCVAPYPSLLPSQDNIDGEANT", "output": "Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects. During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation. In adults, participates in wound healing as well as organ regeneration and tissue remodeling. Promotes also differentiation and proliferation of hematopoietic cells (By similarity)."}]}
+{"id": "function_test_407", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYAHGGLDSNGKPADAVYGQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVFGGFVTEPQEESEEEVEEPEERQQTPEVVPDDSGTFYDQTVSNDLEEHLEEPVVEPEPEPEPEPEPEPVSDIQEDKPEAALEEAAPDDVQKSTSPAPADVAPAQEDLRTFSWASVTSKNLPPSGAVPVTGTPPHVVKVPASQPRPESKPDSQIPPQRPQRDQRVREQRINIPPQRGPRPIREAGEPGDVEPRRMVRHPDSHQLFIGNLPHEVDKSELKDFFQNFGNVVELRINSGGKLPNFGFVVFDDSEPVQKVLSNRPIMFRGAVRLNVEEKKTRAAREGDRRDNRLRGPGGPRGGPSGGMRGPPRGGMVQKPGFGVGRGITTPRQ", "output": "ATP- and magnesium-dependent helicase that plays an essential role in innate immunity. Participates in the DNA-triggered cGAS/STING pathway by promoting the DNA binding and activation of CGAS. Enhances also RIGI-induced type I interferon production probably by helping RIGI at sensing pathogenic RNA. In addition, plays an essential role in stress granule formation. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA. Phosphorylation-dependent sequence-specific endoribonuclease in vitro . Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR ."}]}
+{"id": "function_test_408", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSLLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPAMTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP", "output": "Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 and D3-type G1 cyclins. Phosphorylates SRC, NOS3, VIM/vimentin, p35/CDK5R1, MEF2A, SIPA1L1, SH3GLB1, PXN, PAK1, MCAM/MUC18, SEPT5, SYN1, DNM1, AMPH, SYNJ1, CDK16, RAC1, RHOA, CDC42, TONEBP/NFAT5, MAPT/TAU, MAP1B, histone H1, p53/TP53, HDAC1, APEX1, PTK2/FAK1, huntingtin/HTT, ATM, MAP2, NEFH and NEFM. Regulates several neuronal development and physiological processes including neuronal survival, migration and differentiation, axonal and neurite growth, synaptogenesis, oligodendrocyte differentiation, synaptic plasticity and neurotransmission, by phosphorylating key proteins. Negatively regulates the CACNA1B/CAV2.2 -mediated Ca(2+) release probability at hippocampal neuronal soma and synaptic terminals . Activated by interaction with CDK5R1 (p35) and CDK5R2 (p39), especially in postmitotic neurons, and promotes CDK5R1 (p35) expression in an autostimulation loop. Phosphorylates many downstream substrates such as Rho and Ras family small GTPases (e.g. PAK1, RAC1, RHOA, CDC42) or microtubule-binding proteins (e.g. MAPT/TAU, MAP2, MAP1B), and modulates actin dynamics to regulate neurite growth and/or spine morphogenesis. Phosphorylates also exocytosis associated proteins such as MCAM/MUC18, SEPT5, SYN1, and CDK16/PCTAIRE1 as well as endocytosis associated proteins such as DNM1, AMPH and SYNJ1 at synaptic terminals. In the mature central nervous system (CNS), regulates neurotransmitter movements by phosphorylating substrates associated with neurotransmitter release and synapse plasticity; synaptic vesicle exocytosis, vesicles fusion with the presynaptic membrane, and endocytosis. Promotes cell survival by activating anti-apoptotic proteins BCL2 and STAT3, and negatively regulating of JNK3/MAPK10 activity. Phosphorylation of p53/TP53 in response to genotoxic and oxidative stresses enhances its stabilization by preventing ubiquitin ligase-mediated proteasomal degradation, and induces transactivation of p53/TP53 target genes, thus regulating apoptosis. Phosphorylation of p35/CDK5R1 enhances its stabilization by preventing calpain-mediated proteolysis producing p25/CDK5R1 and avoiding ubiquitin ligase-mediated proteasomal degradation. During aberrant cell-cycle activity and DNA damage, p25/CDK5 activity elicits cell-cycle activity and double-strand DNA breaks that precedes neuronal death by deregulating HDAC1. DNA damage triggered phosphorylation of huntingtin/HTT in nuclei of neurons protects neurons against polyglutamine expansion as well as DNA damage mediated toxicity. Phosphorylation of PXN reduces its interaction with PTK2/FAK1 in matrix-cell focal adhesions (MCFA) during oligodendrocytes (OLs) differentiation. Negative regulator of Wnt/beta-catenin signaling pathway. Activator of the GAIT (IFN-gamma-activated inhibitor of translation) pathway, which suppresses expression of a post-transcriptional regulon of proinflammatory genes in myeloid cells; phosphorylates the linker domain of glutamyl-prolyl tRNA synthetase (EPRS) in a IFN-gamma-dependent manner, the initial event in assembly of the GAIT complex. Phosphorylation of SH3GLB1 is required for autophagy induction in starved neurons. Phosphorylation of TONEBP/NFAT5 in response to osmotic stress mediates its rapid nuclear localization. MEF2 is inactivated by phosphorylation in nucleus in response to neurotoxin, thus leading to neuronal apoptosis. APEX1 AP-endodeoxyribonuclease is repressed by phosphorylation, resulting in accumulation of DNA damage and contributing to neuronal death. NOS3 phosphorylation down regulates NOS3-derived nitrite (NO) levels. SRC phosphorylation mediates its ubiquitin-dependent degradation and thus leads to cytoskeletal reorganization. May regulate endothelial cell migration and angiogenesis via the modulation of lamellipodia formation. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-BMAL1 heterodimer in association with altered stability and subcellular distribution (By similarity)."}]}
+{"id": "function_test_409", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTQFSALALLLIVFVAASFAQSYDDVSAEKRAMRNALVRFGRASGGMRNALVRFGKRSPLDEEDFAPESPLQGKRNGAPQPFVRFGRSGQLDHMHDLLSTLQKLKFANNK", "output": "FMRFamides and FMRFamide-like peptides are neuropeptides.; "}]}
+{"id": "function_test_410", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLDLTNKESESSDNGNSKYEDSIDGREVGTSKPFKEERSLEDLQADLADMAVWMEGLDATKLPLNDPQLLCNGRAFSEVLHNVDKNFFTDGWLETMPENRTTNIMVFRSCTRKLWRKMFDYVNHINRTVVSSRWTDIHERIDGIYESDLPAMVNLGMAVVTLAHIGKNAKRFVDYSKALTSTHKSMMSNVAKMVTTVIDEMPENPCFHEISELHGSQSELNSLSESSGKLNGNGSSERRSNADQILVDAELEIERLRTETENQRKEIERLTKSFETAQHDMSSNSESGDISILEKQNEELRQKRRELEEKNLELDAAVDQFKGIVFELTNENDVLRRSDKERQRLQTVLDAAQSDLDEWKTVANQYQKEAELSKQQDKEIKELLSQNKALKSRLDHHVKSATLEDANKNGIAQLRTQVGGLTALNTELKASLDSKKRCVEQLEIQLIQHKEKVKELEDRKDELIEERNRLENQLIFKEAVTPRSLHESMFEAGNLSFEPFSEKNTLPLEIENKRLTERIQELESLEPLKGELITLKSKNGVLEEEKLFATKQIEELQQQIEDLQENLLKNQEHASGDVVGLKIQLEKAEVEAQQMREAKMRAETNQAQVDEILKKRTAELEVNATALQKAKAVIDELEYNSRPVSEDSMTSVQAFKEMKEENEKLRQKVEKLEIELNTVTQGFEQENRLLTSASHQQVLNRSIDEVMSMRAHAGSEEPQTLLDTQKMSGALPWRSLASETRRELPTAMASILVLGFLVFIAWMFININSALNAPPNA", "output": "Cytoskeletal linker protein, which is essential for attachment of the centrosome to the nucleus . Required for dynein localization to the nuclear envelope . Forms a LINC (LInker of Nucleoskeleton and Cytoskeleton) complex together with unc-84, that may be involved in DNA damage repair ."}]}
+{"id": "function_test_411", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSAESCFGSSGDQSSSKGVATHGGSYVQYNVYGNLFEVSRKYVPPLRPIGRGAYGIVCAATNSETGEEVAIKKIGNAFDNIIDAKRTLREIKLLKHMDHENVIAVKDIIKPPQRENFNDVYIVYELMDTDLHQIIRSNQPLTDDHCRFFLYQLLRGLKYVHSANVLHRDLKPSNLLLNANCDLKLGDFGLARTKSETDFMTEYVVTRWYRAPELLLNCSEYTAAIDIWSVGCILGETMTREPLFPGKDYVHQLRLITELIGSPDDSSLGFLRSDNARRYVRQLPQYPRQNFAARFPNMSAGAVDLLEKMLVFDPSRRITVDEALCHPYLAPLHDINEEPVCVRPFNFDFEQPTLTEENIKELIYRETVKFNPQDSV", "output": "The ANPs-MKK6-MPK4 module is involved in the regulation of plant cytokinesis during meiosis and mitosis. Essential to promote the progression of cytokinesis and for cellularization (formation of the cell plate) during male-specific meiosis. Involved in cortical microtubules organization and stabilization by regulating the phosphorylation state of microtubule-associated proteins such as MAP65-1. Involved in root hair development process. Negative regulator of systemic acquired resistance (SAR) and salicylic acid- (SA) mediated defense response. Required for jasmonic acid- (JA) mediated defense gene expression. May regulate activity of transcription factor controlling pathogenesis-related (PR) gene expression. Seems to act independently of the SAR regulatory protein NPR1 (Nonexpresser of PR1). Phosphorylates MKS1 and transcription factors WRKY25 and WRKY33. The MEKK1, MKK1/MKK2 and MPK4 function in a signaling pathway that modulates the expression of genes responding to biotic and abiotic stresses and also plays an important role in pathogen defense by negatively regulating innate immunity . Phosphorylates MEKK2 upon treatment with flg22 . Involved in stomatal movement regulation by repressing HT1 and HT1-mediated GHR1 phosphorylation ."}]}
+{"id": "function_test_412", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTGGSSSRRRRAEERSSAAGTERNSRREAVGGMGAGPALAALLLAGSVLSATLLAPGRRAEPDLDEKRNVELKMDQALLLIHNELLGTSLTVYWKSDDCYQCTFQPLANVSHGGKPAKPSVAPVSVSTQHGSILQVNSTSEERAACRLEYKFGEFGNYSLLVQHASSGANKIACDIIVNENPVDSNLPVSIAFLVGLALIVAVSLLRLLLSLDDVNNWISKTIASRETDRLINSELGSPSRADPLSADYQPETRRSSANRLRCVDTFRGLALVLMVFVNYGGGKYWYFKHSSWNGLTVADLVFPWFVFIMGTSIFLSMTSILQRGCSKLKLLGKIVWRSFLLICIGVIIVNPNYCLGPLSWDKVRIPGVLQRLGVTYFVVAVLEFFFWKPVPDSCTLESSCFSLRDITSSWPQWLTILTLESIWLALTFFLPVPGCPTGYLGPGGIGDLGKYPHCTGGAAGYIDRLLLGDNHLYQHPSSTVLYHTEVAYDPEGVLGTINSIVMAFLGVQAGKILVYYKDQTKAILTRFAAWCCILGLISIVLTKVSANEGFIPINKNLWSISYVTTLSCFAFFILLILYPVVDVKGLWTGTPFFYPGMNSILVYVGHEVLENYFPFQWKLADEQSHKEHLIQNIVATALWVLIAYVLYKKKLFWKI", "output": "Lysosomal acetyltransferase that acetylates the non-reducing terminal alpha-glucosamine residue of intralysosomal heparin or heparan sulfate, converting it into a substrate for luminal alpha-N-acetyl glucosaminidase."}]}
+{"id": "function_test_413", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSGVSEEDPEGLAPQGLPALGGACLATMDKKLNVLTEKVDRLLHFQEDVTEKLQCVCQGMDHLEQDLHRLEASRELSLAGSGSTPPTTAQAAWPEVLELVRAVRQEGAQHGARLEALFKMVVAVDRAITLVGSTFQNSKVADFIMQGTVPGRKGSLADGPEENKEQAEVAGVKPNHVLTTGGVQADASRTLWEESQKEDIPVRTVEGLPLIINTSLKGADLTQAGASLRQGVEVLGPGQVPLPTEAESRLPETASENTGATLELSVAIDRISEVLTSLKMSQGGGQETSSSKPDCWLSEEAMRLSSGPLPQPLGPLTPDSDIHSGDALPRIPINMQEMATPGELLETQSGSPIGSAEAPGLGTVLEDQIPKGARPFPPLPKRSSNNGGMSAEEEIGSGAEPMRGPSLATRDWRDETVGTTDLQQGIDPGAVSPEPGKDHAAQGPGRTEAGRLSSAAEAAIVVLDDSAAPPAPFEHRVVSIKDTLISAGYTVSQHEVLGGGRFGQVHRCTERSTGLALAAKIIKVKNVKDREDVKNEVNIMNQLSHVNLIQLYDAFESKSSFTLIMEYVDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYLHQHYILHLDLKPENILCVSQTGHQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSFPTDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADTFKGLSEEAKDFVSRLLVKEKSCRMSATQCLKHEWLSHLPAKASGSNVRLRSQQLLQKYMAQSKWKKHFHVVTAVNRLRKFPTCP", "output": "Kinase that phosphorylates MYL2 in vitro . Has been proposed to be calmodulin-dependent , although MYL2 phosphorylation has also been observed in the presence or absence of calmodulin . Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility (By similarity)."}]}
+{"id": "function_test_414", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MYLSKVIIARAWSRDLYQLHQGLWHLFPNRPDAARDFLFHVEKRNTPEGCHVLLQSAQMPVSTAVATVIKTKQVEFQLQVGVPLYFRLRANPIKTILDNQKRLDSKGNIKRCRVPLIKEAEQIAWLQRKLGNAARVEDVHPISERPQYFSGDGKSGKIQTVCFEGVLTINDAPALIDLVQQGIGPAKSMGCGLLSLAPL", "output": "CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).; "}]}
+{"id": "function_test_415", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIGKWRMGLWALAILTVPMYFIVTEGRKTSWGLENEALIVRCPQRGGAINPVEWYYSNTNERIPTQKRNRIFVSRDRLKFLPAKVEDSGIYTCVIRSPESIKTGSLNVTIYKRPPNCKIPDYMMYSTVDGSDKNSKITCPTIALYNWTAPVQWFKNCKALQGPRFRAHMSYLFIDKVSHVDEGDYTCRFTHTENGTNYIVTATRSFTVEEKGFSTFPVITNPPHNYTVEVEIGKTANIACSACFGTASQFVAVLWQINKTRIGSFGKARIQEEKGPNKSSSNGMICLTSLLRITGVTDKDFSLKYDCVAMNHHGVIRHPVRLRRKQPIDHQSTYYIVAGCSLLLMFINVLVIVLKVFWIEVALFWRDIMAPYKTQNDGKLYDAYIIYPRVFRGSAAGTGSVEYFVHYTLPDVLENKCGYKLCIYGRDLLPGQDAATVVESSIQNSRRQVFVLAPHMMHSKEFAYEQEIALHSALIQNNSKVILIEMEPMGEASRLQLGDLQDSLQHLVKMQGTIKWREDHVADKQSLSSKFWKHVRYQMPVPKRPPKMASVAAPLSGKVCLDLKHF", "output": "Receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function (By similarity). Upon tissue injury, induces UCP2-dependent mitochondrial rewiring that attenuates the generation of reactive oxygen species and preserves the integrity of Krebs cycle required for persistent production of itaconate and subsequent GATA3-dependent differentiation of inflammation-resolving alternatively activated macrophages.; "}]}
+{"id": "function_test_416", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSARCCAGQLACCCGSAGCALCCGCCPKFRQSRSTRFMYLFYFTLVIIPCCVMMSPSVMKQMTEHIPFFEDFCKGIKAGDTCENLVGYSAVYRVCFGMACFFFVFCVLTFKVNNSKSCRASIHNGFWFFKLLLLGAMCSGAFFIPDQETFLNVWRYVGAVGSFFFICIQLLLIVEFAHKWNKNWTAGTVRNKLWYASLSLALIMYSIAVGGLALMAVFYTQWDDCMDNKILLGVHGGLCVLISLAAISPCVQNRQPHSGLLQPGLISCYVTYLTFSALTSKPEKVVKDEHGKNVTICVPDFGQDFRRDESMVTWLGTLLLVVCISYSCLTSTTRSSSDALQRRYGAPELEVARCCFCFGPDGEDTEEQQNVKEGPRVIYDEKKGTVYSYSYFHFVLLLASLYVMMTLTSWFHYENATIETFFVGSWSIFWVKMASCWMCVLLYLWTLVAPLCCPSRQFSV", "output": "Restriction factor required to restrict infectivity of gammaretroviruses: acts by inhibiting early step of viral infection and impairing the ability of the viral particle to translocate its content to the cytoplasm (By similarity). Enhances the incorporation of serine into phosphatidylserine and sphingolipids. May play a role in providing serine molecules for the formation of myelin glycosphingolipids in oligodendrocytes."}]}
+{"id": "function_test_417", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDDDGDGSSSPTDDSAAAGLLPLFSRSPAEDLEEKLRRAMEENARLTRALDAILAGHHAHQRALLAPSLSPPPPSATARAPSVSTSCAAREDAAPAVAAAAASTACPSRQQPPTAEPRPKVRTVRVRADAADATDANSMAETVKDGYQWRKYGQKVTRDNPYPRAYFRCAFAPSCPVKKKLQRCAEDRSMLVATYEGEHNHALSTQTTEFVASGCTTSQHAGGSSSSPLPCSISINSSGRTITLDLTNQAGSGSIASCGVEAAAVSGELVTVLSPELRRHLVEEVVQVLKNDAEFVEAVTNAVAARVVDQIPHIPVHL", "output": "Transcription repressor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element. Regulates, probably indirectly, the activation of defense-related genes during defense response (By similarity). Regulates negatively basal innate immunity and XA21-mediated defense against X.oryzae pv. oryzae (Xoo) ."}]}
+{"id": "function_test_418", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAGEEERGDGDPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLSAQIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILRTQLSVRVNAILEKLYGSSGPELRRSLFSLKQIFQEDKDLVPEFVHSEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLVVKTALKLLLVFVEYSENNAPLFIQAVNAVASATGTLPWANLVSILEEKNGADAELLVYTVTLINKTLAALPDQDSFYDVTDALEQQGMEALVQRFLGTAGTDVDLRTQLTLYESALRLEDGDMEEAAAAAAAGGRRERRKPSSEEGKRSRRSLEGGGCPVRAPEPGSTGSASPVGSTPSTGSAPPTNPAFSSTGPASGLLRTSVNLFPTISVGPSVDSSCERSVYKARFLENVAAAETEKQAALAQGRAETLAGATVDDTDGSSGTRELWDSPEPASAPRTPQSPVSRILLRTQRSLEPEPKKPVSPPSPKAEPIQEPPTCVPKLCIGDLDFSDLGEDEDQDTLNVESVEAGKASPFLSSLSPSLSGGPPPPPPPPPPITGSCPPPPPPPLPPPATGSCPPPPPPPPPPIIGSCPPPPPLAAPFTHSALDGPRHPTKRKTVKLFWRELKLTGGPGCSRSRFGPCPTLWASLEPVSVDTARLEHLFESRAKDVLPTKKAGEGRRTMTVVLDPKRSNAINIGLTTLPPVHVIKAALLNFDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDVPLGPAENFLMTLASIGGLAARLQLWAFKLDYESMEREIAEPLFDLKVGMEQLVHNATFRCILATLLAVGNFLNGSQSSGFELSYLEKVSEVKDTVRRQSLLYHLCSLVLQTRPDSSDLYSEIPALTRCAKVDFEQLTENLGQLECRSQAAEDSLRSLAKHELSPALRARLTHFLAQCTRRVAMLRVVHRRVCNRFHAFLLYLGYTPQAARDVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERNKTRGRMITETEKFSGVAGEAPNNLSVPVAVGSGPGQGDTDNHASMKSLLTSRPEDATHSRRSRGMVQSSSPVSHTAVGPSAASPEETAASGLPTDTSDEIMDLLVQSVTKSGPRALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKAPGLEV", "output": "Required for the assembly of F-actin structures, such as stress fibers. Depends on the Rho-ROCK cascade for its activity. Contributes to the coordination of microtubules with actin fibers and plays a role in cell elongation. Acts synergistically with ROCK1 to promote SRC-dependent non-apoptotic plasma membrane blebbing (By similarity)."}]}
+{"id": "function_test_419", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGDVKLFASSHMSKTSHSVDPSKVSSMPLTEAPAFILPPRNLCVKEGATAKFEGRVRGYPEPQVTWHRKGQAITNGGRFLLDCGVRGTFSLVIHTVREEDKGKYTCEASNGSGARQVTVELTVEGNSMKKRDQPVLSKASGFPGETRPSIWGECPPKFATKLGRAVVKEGQMWRFSCKITGRPPPQVTWLKGNVPLQPSARVSMSEKNGMQILEIRGVTRDDLGVYTCMVVNGSGKASMSAELSIPGLDNASRLAVRGTKAPSPDIRKEVTNGVSKDPETVAESKNCPSPQRSGSSARATNSHLKSPQEPKPKLCEDAPRKVPQSSILQKSTSTITLQALKVQPEARVPAIGSFSPGEDRKSLAAPQQATLPTRQSSLGGSVGNKFVTGNIPRESQRESTFPRFESQPQSQEVTEGQTVKFICEVSGIPKPDVGWFLEGIPVRRREGITEVYEDGVSHHLCLLRARTRDSRKYSCTASNSLGQVSCSWSLLVDRPNLAQTAPSFSSVLKDSVVIEGQDFVLRCSVQGTPAPRVTWLLNGQPIQFAHSICEAGVAELHIQDALPEDRGTYTCLAENAMGQVSCSATVTVQEKKGEGEREHRLSPARSKPIAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHDGNEIQESEDFHFEQKGGWHSLCIQEVFPEDTGTYTCEAWNSAGEVRTRAVLTVQEPHDGTQPWFISKPRSVTATLGQSVLISCAIAGDPFPTVHWLRDGRALSKDSGHFELLQNEDVFTLVLKNVQPWHAGQYEILLKNRVGECSCQVSLMLHNSPSRAPPRGREPASCEGLCGGGGVGAHGDGDRHGTLRPCWPARGQGWPEEEDGEDVRGLLKRRVETRLHTEEAIRQQEVGQLDFRDLLGKKVSTKTVSEDDLKDIPAEQMDFRANLQRQVKPKTISEEERKVHSPQQVDFRSVLAKKGTPKTPVPEKAPPKAATPDFRSVLGGKKKSPSENGGNSAEVLNVKAGESPTPAGDAQAIGALKPVGNAKPAETPKPIGNAKPTETLKPVGNTKPAETLKPIANAQPSGSLKPVTNAQPAEPQKPVGNAKSAETSKPAGKEEVKEVKNDVNCKKGQVGATGNEKRPESQGSAPVFKEKLQDVHVAEGEKLLLQCQVISDPPATVTWSLNGKTLKTTKFIVLAQEGSRFSVSIEKALPEDRGLYKCVAKNSAGQAECSCQVTVDDAQTSENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPTKAAMPPQIIQFPEDQKVRAGEPVELFGKVAGTQPITCKWMKFRKQIQESEHIKVENGESGSKLTILAARQEHCGCYTLVVENKLGSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYNVEIWDTEDKVWKELATCRSTSFNVQDLLPDREYKFRVRAVNVYGTSEPSQESELTAVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTVNTEQKVSDVYDIEERLGSGKFGQVFRLVEKKTGKIWAGKFFKAYSAKEKDNIRQEISIMNCLHHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGSPTSPINAEKLESEDDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGEGEEGGEEEEEEEE", "output": "Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phosphorylates PTK2B/PYK2 and myosin light-chains. Involved in the inflammatory response (e.g. apoptosis, vascular permeability, leukocyte diapedesis), cell motility and morphology, airway hyperreactivity and other activities relevant to asthma. Required for tonic airway smooth muscle contraction that is necessary for physiological and asthmatic airway resistance. Necessary for gastrointestinal motility. Implicated in the regulation of endothelial as well as vascular permeability, probably via the regulation of cytoskeletal rearrangements. In the nervous system it has been shown to control the growth initiation of astrocytic processes in culture and to participate in transmitter release at synapses formed between cultured sympathetic ganglion cells. Critical participant in signaling sequences that result in fibroblast apoptosis. Plays a role in the regulation of epithelial cell survival. Required for epithelial wound healing, especially during actomyosin ring contraction during purse-string wound closure. Mediates RhoA-dependent membrane blebbing. Triggers TRPC5 channel activity in a calcium-dependent signaling, by inducing its subcellular localization at the plasma membrane. Promotes cell migration (including tumor cells) and tumor metastasis. PTK2B/PYK2 activation by phosphorylation mediates ITGB2 activation and is thus essential to trigger neutrophil transmigration during acute lung injury (ALI). May regulate optic nerve head astrocyte migration. Probably involved in mitotic cytoskeletal regulation. Regulates tight junction probably by modulating ZO-1 exchange in the perijunctional actomyosin ring. Mediates burn-induced microvascular barrier injury; triggers endothelial contraction in the development of microvascular hyperpermeability by phosphorylating MLC. Essential for intestinal barrier dysfunction. Mediates Giardia spp.-mediated reduced epithelial barrier function during giardiasis intestinal infection via reorganization of cytoskeletal F-actin and tight junctional ZO-1. Necessary for hypotonicity-induced Ca(2+) entry and subsequent activation of volume-sensitive organic osmolyte/anion channels (VSOAC) in cervical cancer cells."}]}
+{"id": "function_test_420", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAEARLLRRRRLCLAVPFVWVVAVAVSRVGANTEGDALYSLRQSLKDANNVLQSWDPTLVNPCTWFHVTCNPDNSVIRVDLGNAQLSGALVPQLGQLKNLQYLELYSNNISGTIPNELGNLTNLVSLDLYLNNFTGFIPETLGQLYKLRFLRLNNNSLSGSIPKSLTNITTLQVLDLSNNNLSGEVPSTGSFSLFTPISFANNKDLCGPGTTKPCPGAPPFSPPPPFNPPTPTVSQGDSKTGAIAGGVAAAAALLFAVPAIGFAWWRRRKPEEHFFDVPAEEDPEVHLGQLKRFSLRELQVATDNFSNKNILGRGGFGKVYKGRLADGSLVAVKRLKEERTPGGELQFQTEVEMISMAVHRNLLRLRGFCMTPTERLLVYPYMANGSVASRLRERQPNDPPLEWQTRTRIALGSARGLSYLHDHCDPKIIHRDVKAANILLDEDFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGKSSEKTDVFGYGIMLLELITGQRAFDLARLANDDDVMLLDWVKGLLKEKKVEMLVDPDLQSGFVEHEVESLIQVALLCTQGSPMDRPKMSEVVRMLEGDGLAERWEEWQKVEVVRQEAELAPRHNDWIVDSTYNLRAMELSGPR", "output": "LRR receptor kinase involved in positive regulation of somatic embryogenesis and defense response against the rice blast fungus pathogen Magnaporthe oryzae . Involved in the positive regulation of receptor kinase-mediated immunity. Required for immunity mediated by the LRR receptor kinases XA21 and XA26/XA3 which recognize effectors from the bacterial pathogen Xanthomonas oryzae pv. oryzae (Xoo). Required for the immune response mediated by the LRR receptor kinase FLS2 which recognizes specifically the bacterial flagellin (flg22) effector. Kinase activity and direct interaction with the immune receptors is critical for their function . Involved in the regulation of plant growth through the brassinosteroid (BR) signaling pathway ."}]}
+{"id": "function_test_421", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSLLLFLLSFLLDGPQGQMESYFLQVQRIVKAQEGLCIFVPCSFSSPEGKWLNRSPLYGYWFKGIRKPSLSFPVATNNKDKVLEWEARGRFQLLGDISKKNCSLLIKDVQWGDSTNYFFRMERGFERFSFKEEFRLQVEALTQKPDIFIPEVLEPGEPVTVVCLFSWTFNQCPAPSFSWMGDAVSFQESRPHTSNYSVLSFIPGLQHHDTELTCQLDFSRMSTQRTVRLRVAYAPRSLAISIFHDNVSVPDLHENPSHLEVQQGQSLRLLCTADSQPPATLSWVLEDQVLSWSSPVGSRTLALELPWVKAGDSGHYTCQAENRLGSQQHTLDLSVLYPPQDLRVTVSQANRTVLEILRNAISLPVLEGQSLCLVCVTYSNPPANVSWAWVTQTLIPIQSSEPGVLELPLVQREHEGEFTCAAQNPLGAQRISLSLSVHYPPQMSSPSCSWEAKGLHCNCSSRAWPAPSLRWRLGEGLLEGNSSNASFTVTFSSLGPWVNSSLSLLQELGPSLWLSCESWNTHGAQTTSVLLLPDKDSATAFSKGAVLGFGITALLALCLIVVIVKTLQKKGTQEEPSRPKLSRGSTILDYINVVPKTRSLARNWKAEPDAPSRSSPLDTHFPKPKKKQKDPHFTYPGCPDPTSSSQVPVSENNPEELHYAALNFSRLRLQETQDPQDTYSDYTEVRVH", "output": "Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid . The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, seems to act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules (By similarity). Involved in negative regulation of B-cell antigen receptor signaling and specifically acts on B1 cells to inhibit Ca(2+) signaling, cellular expansion and antibody secretion . The inhibition of B cell activation is dependent on PTPN6/SHP-1 . In association with CD24 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90 . In association with CD24 may regulate the immune repsonse of natural killer (NK) cells (By similarity). Plays a role in the control of autoimmunity . During initiation of adaptive immune responses by CD8-alpha(+) dendritic cells inhibits cross-presentation by impairing the formation of MHC class I-peptide complexes. The function seems to implicate recruitment of PTPN6/SHP-1, which dephosphorylates NCF1 of the NADPH oxidase complex consequently promoting phagosomal acidification .; "}]}
+{"id": "function_test_422", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPCARGSWLAKLSIVAQLINFGAFCHGRQTQPWPVRFPDPRQEHFIKSLPEYHIVSPVQVDAGGHVLSYGLHHPVTSSRKKRAAGGSGDQLYYRISHEEKDLFFNLTVNWEFLSNGYVVEKRYGNLSHVKMVASSGQPCHLRGTVLQQGTTVGIGTAALSACQGLTGFFHLPHGDFFIEPVKKHPLTEEGSYPHVVYRRQSIRAPETKEPICGLKDSLDNSVKQELQREKWERKTLRSRSLSRRSISKERWVETLVVADTKTVEYHGSENVESYILTIMNMVTGLFHSPSIGNLVHIVVVRLILLEEEEQGLKIVHHAEKTLSSFCKWQKSINPKSDLNPVHHDVAVLITRKDICAGVNRPCETLGLSQLSGMCQPHRSCNINEDSGLPLAFTIAHELGHSFGIQHDGKENDCEPVGRHPYIMSQQIQYDPTPLTWSKCSKEYITRFLDRGRGFCLDDIPSKKGLKSNVIAPGVIYDVHHQCQLQYGPNATFCQEVENVCQTLWCSVKGFCRSKLDAAADGTRCGEKKWCMAGKCITVGKKPESIPGGWGRWSPWSHCSRTCGAGAQSAERLCNNPEPKFGGKYCTGERKRYRLCNVHPCRSDTPTFRQMQCSEFDTVPYKNQFYRWFPVFNAAHPCELYCRPIDEQFSERMLEAVIDGTPCFEGGNSRNVCINGICKRVGCDYEIDSNATEDRCGVCLGDGSACQTVKKLFRQKEGSGYVDIGLIPKGARDIRVMEIKAAGNFLAIRSEDPEKYYLNGGFIIQWNGNYKLAGTVFQYDRKGDLEKLIAPGPTNESVWLQLLFQVTNPGIKYEYTVRKDGLDNDVEKLLYFWQFGRWTECSVTCGTGIRRQAAHCVKKGHGIVKTTFCNPETQPSVRQKKCHEKDCPPRWWAGEWEACSTTCGPYGEKKRTVLCIQTMGSDEQALPATDCQHLLKPKALVSCNRDILCPSDWTVGNWSECSVSCGGGVRIRSVTCAKNLNEPCDKTRKPNSRALCGLQQCPFSRRVLKPNKDIAPSGKNQSTAEHDPFKPIPAPTSRPTPLSTPTVPESMSTSTPTINSLGSTIASQEDANGMGWQNNSTQAEEGSHFPTSSGSTSQVPVTSWSLSIQPDDENVSSSAIGPTSEGDFWATTTSDSGLSSSDAMTWQVTPFYSTMTTDPEVEIHSGSGEDSDQPLNKDKSNSVIWNKIGVPEHDAPMETDAELPLGPPPTSYMGEEPSWPPFSTKMEGSLPAWSFKNETPRDDGMIAEKSRKIPLPLAGDHHPATSEKLENHDKLALPNTTNPTQGFGPVLTEEDASNLIAEGFLLNASDYKHLMKDHSPAYWIVGNWSKCSTTCGLGAYWRSVECSSGVDADCTTIQRPDPAKKCHLRPCAGWRVGNWSKCSRNCSGGFKIREVQCMDSLDHHRSLRPFHCQFLAGAPPPLSMSCNLEPCGEWQVEPWSQCSRSCGGGVQERGVSCPGGLCDWTKRPATTVPCNRHLCCHWATGNWELCNTSCGGGSQKRTIHCIPSENSTTEDQDQCLCDHQVKPPEFQTCNQQACRKSADLTCLKDRLSISFCQTLKSMRKCSVPSVRAQCCLSCPQAPSIHTQRQRKQQLLQNHDML", "output": "Metalloprotease that plays a role in the degradation of COMP (By similarity). Cleaves also alpha-2 macroglobulin and aggregan. Has anti-tumorigenic properties (By similarity)."}]}
+{"id": "function_test_423", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGNITTENSSLSCPIDHTIHQTLAPVVYVTVLVVGFPANCLSLYFGYLQIKARNELGVYLCNLTIADLFYICSLPFWLQYVLQHDDWSHGDLSCQVCGILLYENIYISVGFLCCISIDRYLAVAHPFRFHQFRTLKAAVGVSVLIWAKELLTSIYFLNHKEVIEDEDQHRVCFEHYPIQAWQRSINYYRFLVGFLFPICLLLASYQGILRAVRRSHGTQKSRKDQIQRLVLSTVVIFLACFLPYHVLLLVRSLWERNCEFAKSIFNVYHFSLLLTSFNCVADPVLYCFVSETTHRDLARLRGACLAVLTCSRTSRAREAYPLGAPEASGKSGAQGEEPELLTKLHSAFQTPSSLGVGGPSTVGLA", "output": "Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Also functions as a metastasis suppressor gene in prostate cancer."}]}
+{"id": "function_test_424", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAARPPASLSYRTTGSTCLHPLSQLLGIPLDQVNFVACQLFALSAAFWFRIYLHPGKASPEVRHTLATILGIYFVVFCFGWYAVHLFVLVLMCYGVMVTASVSNIHRYSFFVAMGYLTICHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRKAEDLSAEQHRLAVKAKPSLLEYLSYHLNFMSVIAGPCNNFKDYVAFIEGRHIHMKLLEVNWTQRGFQSLPEPSPMGAVIQKLCVTLMSLLLFLTLSKSFPVTFLIDDWFVHKANFLSRLWYLYVVMQAAKPKYYFAWTLADAVHNAAGFGFNGMDTDGKSRWDLLSNLNIWKIETATSFKMYLENWNIQTSTWLKCVCYERVPWYPTVLTFLLSALWHGVYPGYYFTFLTGVPVTLAARAVRNNYRHHFLSSKARKIAYDVVTWAVTQLAVSYTAAPFVMLAVEPTISLYKSVFFFLHIICLLIILFLPIKPHQPQRQSRSPNSVKKKAD", "output": "Acyltransferase which catalyzes the transfert of an acyl group from an acyl-CoA towards a lysophospholipid producing a phospholipid and participates in the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle . Acts on lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3-phospho-L-serine or LPS) and lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE), and to a lesser extend lysophosphatidylcholine . Prefers oleoyl-CoA as the acyl donor and 1-oleoyl-LPE as acceptor . May play a role in neurite outgrowth during neuronal differentiation ."}]}
+{"id": "function_test_425", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSHGHSHGGGGCRCAAEREEPPEQRGLAYGLYLRIDLERLQCLNESREGSGRGVFKPWEERTDRSKFVESDADEELLFNIPFTGNVKLKGVIIMGEDDDSHPSEMRLYKNIPQMSFDDTEREPEQTFSLNRDITGELEYATKISRFSNVYHLSIHISKNFGADTTKIFYIGLRGEWTELRRHEVTICNYEASANPADHRVHQVTPQTHFIS", "output": "Promotes megakaryocyte differentiation by up-regulating RUNX1 expression . Regulates RUNX1 expression by activating the proximal promoter of the RUNX1 gene and by enhancing the translation activity of an internal ribosome entry site (IRES) element in the RUNX1 gene (By similarity)."}]}
+{"id": "function_test_426", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAVTAFNTLKLVSSSLDPIPSVSCSSYSFSLIYVGSPYKRCLKQSCSVRAMTSSSSAASSSSSSFGSRMEESIRKTVTENTVVIYSKTWCSYCTEVKTLFKRLGVQPLVVELDQLGPQGPQLQKVLERLTGQHTVPNVFVCGKHIGGCTDTVKLNRKGDLELMLAEANGKNGQS", "output": "Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. Can assemble a [2Fe-2S] cluster, but cannot transfer it to an apoferredoxin."}]}
+{"id": "function_test_427", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDVNLAPLRAWDDFFPGSDRFARPDFRDISKWNNRVVSNLLYYQTNYLVVAAMMISVVGFLSPFNMILGGVIVVLVFMGFVWAAHNKDILRRMKKQYPTAFVMVVMLASYFLISMFGGVMVFVFGITLPLLLMFIHASLRLRNLKNKLENKMEGIGLKKTPMGIILDALEQQEDNINKFADYISKARE", "output": "Regulates intracellular concentrations of taurine and glutamate (By similarity). Negatively modulates SLC1A1/EAAC1 glutamate transport activity by decreasing its affinity for glutamate in a PKC activity-dependent manner . Plays a role in the retention of SLC1A1/EAAC1 in the endoplasmic reticulum (By similarity)."}]}
+{"id": "function_test_428", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKSAISSSLFFNSKNLLNPNPLSRFISLKSNFLPKLSPRSITSHTLKLPSSSTSALRSISSSMASSFNPEQARVPSALPLPAPPLTKFNIGLCQLSVTSDKKRNISHAKKAIEEAASKGAKLVLLPEIWNSPYSNDSFPVYAEEIDAGGDASPSTAMLSEVSKRLKITIIGGSIPERVGDRLYNTCCVFGSDGELKAKHRKIHLFDIDIPGKITFMESKTLTAGETPTIVDTDVGRIGIGICYDIRFQELAMIYAARGAHLLCYPGAFNMTTGPLHWELLQRARATDNQLYVATCSPARDSGAGYTAWGHSTLVGPFGEVLATTEHEEAIIIAEIDYSILEQRRTSLPLNRQRRGDLYQLVDVQRLDSK", "output": "Omega-amidase involved in the metabolism of asparagine. Probably also closely coupled with glutamine transamination in the methionine salvage cycle. Can use alpha-ketosuccinamate and alpha-hydroxysuccinamate as substrates, producing respectively oxaloacetate and malate, or alpha-ketoglutaramate, producing alpha-ketoglutarate."}]}
+{"id": "function_test_429", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSLLRRPWVLVVGLLLIMSYVGAECEEEEKEYPSRYPIAYFEWENVKIPMTICLWLIGASIAKIIFNLIPHLNELFPDSALLIMIGLIIGIIFKLIGVNKNAFFLESEVFMLYLLPPLVFDAGYFMPARQFFDNFGSILCFAMIGTSFNIVAIALSLWAISLTGLFSVETPLMHMLLFGSVAADVDPVAVIVIFEELKVNEVLFIAVFGESLLNDGVAVVLYRMFLTFSEIGTENLITSDYINGGVSFLVVAFGGIGIGLLFAFLTSLVTRFARDEEVKVLNSVFILILPYTCYLCGELFGLSSIMAIVFCGAAMRQYCRENVDPDTVKATESFIKVLSLASETVIFVFLGLSTVSSNHHWDTSFIVLTVVFCLIYRTLGVVVMCYFLNKYRLNKYTKVDQFIMAYGGLRGAIAYGLVVAIPDFIPGKNMFVTSCIIVIYFTVFLQGITLKPIAEFLQVEKKNVHSKNMIEHIYSELIDTTMAGMEDIAGFKGHHWIRDSWNALNNNYLRPILVNKNNMKEMDKTKLVRKYKHLVDEDAKKIARGDLNSNMVFTKALIEHTRSRTNTMIDGVSSTSKIDFTKHMKENFGVTVYDDHSTVPMTPTHLFQETTEVEYSVRSEINDNDGFENDGYESDESGSFHERV", "output": "Na(+)/H(+) antiporter that promotes normal di- or tripeptide transporter function, recovery following the peptide-induced acidification of the intestinal cytoplasm and maintenance of the peptide-dependent intestinal pH homeostasis. Regulator of free fatty acid uptake from the diet together with the dipeptide transporter pept-1. May play a timekeeper role in defecation cycle but is not necessary for pbo-4-dependent proton release. May play a role in the regulation of lifespan independent of the stress response pathway."}]}
+{"id": "function_test_430", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MILGSLSRAGPLPLLRQPPIMQPPMDLKQILPFPLEPAPTLGLFSNYSTMDPVQKAVLSHTFGGPLLKTKRPVISCNVCQIRFNSQSQAEAHYKGNRHARRVKGIEAAKTRGREPSVRESGDPAPAGSIPPSGDGVAPRPVSMENGLGPAPGSPEKQPGSPSPPSVPESGQGVTKGEGGTSVPASLPGGSKEEEEKAKRLLYCALCKVAVNSLSQLEAHNKGTKHKTILEARSGLGPIKAYPRLGPPTPGEPEAPAQDRTFHCEICNVKVNSEVQLKQHISSRRHRDGVAGKPNPLLSRHKKPRGAAELAGTLTFSKELPKSLAGGLLPSPLAVAAVMAAAAGSPLSLRPAPAAPLLQGPPITHPLLHPAPGPIRTAHGPILFSPY", "output": "RNA-binding protein that affects the localization and the translation of a subset of mRNA. May play a role in adipogenesis through binding to the 3'-UTR of CEBPA mRNA and regulation of its translation. Targets ITPR1 mRNA to dendrites in Purkinje cells, and may regulate its activity-dependent translation. With ELAVL1, binds the 3'-UTR of p53/TP53 mRNAs to control their nuclear export induced by CDKN2A. Hence, may regulate p53/TP53 expression and mediate in part the CDKN2A anti-proliferative activity. May also bind CCNB1 mRNA. Alternatively, may also regulate p53/TP53 activity through direct protein-protein interaction. Interacts with p53/TP53 and promotes cell-cycle arrest over apoptosis enhancing preferentially the DNA binding and transactivation of p53/TP53 on cell-cycle arrest target genes over proapoptotic target genes. May also regulate the ubiquitination and stability of CDKN1A promoting DNA damage-induced cell cycle arrest. Also plays a role in megakaryocytes differentiation."}]}
+{"id": "function_test_431", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTLLGSEHSLLIRRKFRSVLQLRLQQRRTQEQLANQGLIPPLKGPTEFHDPRKQLDSAKTEDSLRRKGRNRSDRASLVTMHILQASTAERSIPTAQMKLKRARLADDLNEKIALRPGPLELVEKNILPMDSSVKEAIKGTEVSLSKAADAFAFEDDSSRDGLSPDQARSEDPQGSTGSTPDIKSTEAPLDTIQDLTPGSESDKNDAASQPGNQSDPGKQVLGPLSTPIPVHTAVKSKSLGDSKNRHKKPKDPKPKVKKLKYHQYIPPDQKAEKSPPPMDSAYARLLQQQQLFLQLQILSQQQQQQQQQQQQQQQQQQQQQRFSYPGMHQTHLKEPNEQMARNPNPSSTPLSNTPLSPVKNSISGQTGVSSLKPGPLPPNLDDLKVSELRQQLRIRGLPVSGTKTALVDRLRPFQDCAGNPVPNFGDITTVTFPVTPNTLPSYQSSPTGFYHFGSTSSSPPISPASSDLSAAGSLPDTFTDASPGFGLHASPVPACTDESLLSSLNGGSGPSEPDGLDSEKDKMLVEKQKVINQLTWKLRQEQRQVEELRMQLQKQKSSCSDQKPLPFLATTIKQEDVSSCPFAPQQASGKGQGHSSDSPPPACETAQLLPHCVESSGQTHVLSSTFLSPQCSPQHSPLGGLKSPQHISLPPSPNNHYFLASSSGAQRENHGVSSPSSSQGCAQMTGLQSSDKVGPTFSIPSPTFSKSSSAVSDITQPPSYEDAVKQQMTRSQQMDELLDVLIESGEMPADAREDHSCLQKIPKIPGSSCSPTAIPPKPSASFEQASSGGQMAFDHYANDSDEHLEVLLNSHSPIGKVSDVTLLKIGSEEPPFDSIMDGFPGKAAEDLFSAHELLPGPLSPMHAQLSPPSVDSSGLQLSFTESPWETMEWLDLTPPSSTPGFSNLTSSGPSIFNIDFLDVTDLNLNSPMDLHLQQW", "output": "Smooth muscle cells (SM) and cardiac muscle cells-specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF-target genes. Plays a crucial role in cardiogenesis, urinary bladder development, and differentiation of the smooth muscle cell lineage (myogenesis). Isoform 1 mediates the cardiac transcription factor MEF2C-dependent transcription. Isoform 1 and isoform 3 are more active than isoform 2 and isoform 4 in stimulating cardiac muscle promoters."}]}
+{"id": "function_test_432", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGITYLHISVATTALSFVGLQVWTELSLDRLRADGIITKNISLGNSENTLELLLSSHTTIALLASFVLNIYILLVLSLKTLFFGDLYAIETRKLVERLANYIIYKGTFLPFVVPRTVFQGVLWTIWLTVLCTLKMFQALARDRLDRLNASPSSTPWTYFRVYSALFMVLSTDLCWIKLSLMIYNTVGSSVYLLLLFEPCGIAFETLQALLIHGFQLLDMWINHLAVKNSDCQRSKFYDSMTAGSLLEWKGLLNRNLGFFLDMATLVMALGHYLHIWWLHGMAFHLVDAVLFLNIRALLSSILKRIKGYIKLRVALGALHAALLDATSEELRDYDDECAICREPMAKAKRLHCNHLFHLGCLRSWLDQGLNEVYSCPTCRKPLFVGRTESEANPSRGEVSSDEHLARQFERQNNSVHALTTGMFPTETPNFTESDPWRNSEVDPSWLQTWSDQGVDVVGSSAGSRSVGLGQVQLMMRHLASVGEGSAQTTLDDASWGLWPMNPSQASTSSTYVPPGAGGRTGGLHLRTVSRAANNMASILAMAETVREVLPHVPDEIIFQDLQRTNSVSVTVNNLLQM", "output": "E3 ubiquitin protein ligase that acts as positive regulator of RPM1- and RPS2-dependent hypersensitive response (HR), in association with RIN2. Probably not required for RPM1 degradation during HR."}]}
+{"id": "function_test_433", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLLGASLVGALLFSKLVLKLPWTQVGFSLLLLYLGSGGWRFIRVFIKTVRRDIFGGMVLLKVKTKVRRYLQERKTVPLLFASMVQRHPDKTALIFEGTDTHWTFRQLDEYSSSVANFLQARGLASGNVVALFMENRNEFVGLWLGMAKLGVEAALINTNLRRDALRHCLDTSKARALIFGSEMASAICEIHASLEPTLSLFCSGSWEPSTVPVSTEHLDPLLEDAPKHLPSHPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMASLVYYGFRMRPDDIVYDCLPLYHSAGNIVGIGQCLLHGMTVVIRKKFSASRFWDDCIKYNCTIVQYIGELCRYLLNQPPREAESRHKVRMALGNGLRQSIWTDFSSRFHIPQVAEFYGATECNCSLGNFDSRVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGQPGQLVGRIIQQDPLRRFDGYLNQGANNKKIANDVFKKGDQAYLTGDVLVMDELGYLYFRDRTGDTFRWKGENVSTTEVEGTLSRLLHMADVAVYGVEVPGTEGRAGMAAVASPISNCDLESFAQTLKKELPLYARPIFLRFLPELHKTGTFKFQKTELRKEGFDPSVVKDPLFYLDARKGCYVALDQEAYTRIQAGEEKL", "output": "Mediates the import of long-chain fatty acids (LCFA) into the cell by facilitating their transport across cell membranes . Appears to be the principal fatty acid transporter in small intestinal enterocytes . Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates, which prevents fatty acid efflux from cells and might drive more fatty acid uptake (By similarity). Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis . Probably involved in fatty acid transport across the blood barrier (By similarity). Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-CoA. Prevents light-induced degeneration of rods and cones ."}]}
+{"id": "function_test_434", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTAGQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDLDPEREVTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKIDSGELDPERMGSGIQYGDISLRQLRQPRSAQAVAPQPCGC", "output": "Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state . Protein transport (By similarity). Probably involved in vesicular traffic (By similarity). Acts as a regulator of platelet alpha-granule release during activation and aggregation of platelets ."}]}
+{"id": "function_test_435", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MQLLLSSVCMALTSAVIGFAYYQKQQFYPAVVYITKSNASMGVIYIQFFVIVFMFGKLLSKIFLGTLRAAEFEHLLERFWYALTETCLAFTVFRDDFNPRFVALFTVLLFLKSFHWLAEERVDFMERSPVLGWLFHIRVGSLLTVLGILDYVLLIHAYNSTLVRGPTVQLVFGFEYAILLTVIASTAIKYVLHAAEMRTDTPWENKAVFLLYTELVIGLIKVVLYILFVVIMAKIYALPMFVFRPMFFTIRNFRKALNDVIMSRRAIRNMNTLYPDATPEELRQSDNICIICREDMVNHSKKLPCGHIFHTTCLRSWFQRQQTCPTCRLNILRTPTVNSTAMPRQGDEAVAAAAGNPIPAAAGVQPAGGVPPPAPTAVVDGNQARADVNVAGGQALPPNFADLFGDASGLPNGLPNLAGLQIPPPPVMPMISPFMIPPHFGYLTPLPPPPIPQDLTNFTDEELRAMEGLQRDHIVQRLKLLQNINLMLDSAGIMMSQYQSLSARLQLTAVTPATAVNGSADSSVYDMPSTSATAMAQLETHQVTPTAAASSASPTMPAEKVTIEDLGADADEDDIPSTATEAVSIPNSDADFEENSSELGELRKRRLKFLEERNKSAATNERTTAE", "output": "Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates, promoting their degradation. Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Also promotes the degradation of normal but naturally short-lived proteins. Protects cells from ER stress-induced apoptosis. Sequesters p53 in the cytoplasm and promotes its degradation, thereby negatively regulating its biological function in transcription, cell cycle regulation and apoptosis."}]}
+{"id": "function_test_436", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAAVRGVRVVGSSPGLLLGRGMRAFLLLLWLAARGSALYFHIGETEKKCFIEEIPDETMVIGNYRTQLYDKQREEYQPATPGLGMFVEVKDPEDKVILARQYGSEGRFTFTSHTPGEHQICLHSNSTKFSLFAGGMLRVHLDIQVGEHANDYAEIAAKDKLSELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTNQRVLWWSILQTLILVAIGVWQMRHLKSFFEAKKLV", "output": "Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to membranes of the early secretory pathway. Increases coatomer-dependent activity of ARFGAP2. Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi membranes; specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. May be involved in organization of intracellular membranes, such as of the ER-Golgi intermediate compartment and the Golgi apparatus. Involved in ER localization of PTPN2 (By similarity)."}]}
+{"id": "function_test_437", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGVPAVPEASSPRWGTLLLAIFLAASRGLVAAFKVTTPYSLYVCPEGQNATLTCRILGPVSKGHDVTIYKTWYLSSRGEVQMCKEHRPIRNFTLQHLQHHGSHLKANASHDQPQKHGLELASDHHGNFSITLRNVTPRDSGLYCCLVIELKNHHPEQRFYGSMELQVQAGKGSGSTCMASNEQDSDSITAAALATGACIVGILCLPLILLLVYKQRQVASHRRAQELVRMDSNTQGIENPGFETTPPFQGMPEAKTRPPLSYVAQRQPSESGRYLLSDPSTPLSPPGPGDVFFPSLDPVPDSPNSEAI", "output": "Immunoregulatory receptor which inhibits the T-cell response . May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling . May stimulate MMP14-mediated MMP2 activation (By similarity)."}]}
+{"id": "function_test_438", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSKTLKKKKHWLSKVQECAVSWAGPPGDLGAEIRGGAERGEFPYLGRLRDEAGGGGGTCCVVSGKAPSPGDVLLEVNGTPVSGLTNRDTLAVIRHFREPIRLKTVKPGKVINKDLRHYLSLQFQKGSIDHKLQQVIRDNLYLRTIPCTTRAPRDGEVPGVDYNFISVEQFKALEESGALLESGTYDGNFYGTPKPPAEPSPFQPDPVDQVLFDNEFDTESQRKRTTSVSKMERMDSSLPEEEEDEDKEAVNGSGSMETREMHSETSDCWMKTVPSYNQTNSSMDFRNYMMRDENLEPLPKNWEMAYTDTGMIYFIDHNTKTTTWLDPRLCKKAKAPEDCEDGELPYGWEKIEDPQYGTYYVDHLNQKTQFENPVEEAKRKKQLGQAEIHSAKTDVERAHFTRDPSQLKGVLVRASLKKSTMGFGFTIIGGDRPDEFLQVKNVLKDGPAAQDGKIAPGDVIVDINGNCVLGHTHADVVQMFQLVPVNQYVNLTLCRGYPLPDDSEDPVVDIVAATPVINGQSLTKGETCMNTQDFKLGAMVLDQNGKSGQILASDRLNGPSESSEQRASLASSGSSQPELVTIPLIKGPKGFGFAIADSPTGQKVKMILDSQWCQGLQKGDIIKEIYHQNVQNLTHLQVVEVLKQFPVGADVPLLILRGGPCSPTKTAKTKTDTKENSGSLETINEPIPQPMPFPPSIIRSGSPKLDPSEVYLKSKTLYEDKPPNTKDLDVFLRKQESGFGFRVLGGDGPDQSIYIGAIIPLGAAEKDGRLRAADELMCIDGIPVKGKSHKQVLDLMTTAARNGHVLLTVRRKIFYGEKQPEDESHQAFSQNGSPRLNRAELPTRSAPQEAYDVTLQRKENEGFGFVILTSKSKPPPGVIPHKIGRVIDGSPADRCGGLKVGDHISAVNGQSIVDLSHDNIVQLIKDAGVTVTLTVVAEEEHHGPPSGTNSARQSPALQHRPMGQAQANHIPGDRIALEGEIGRDVCSSYRHSWSDHKHLAQPDTAVISVVGSRHNQSLGCYPVELERGPRGFGFSLRGGKEYNMGLFILRLAEDGPAIKDGRIHVGDQIVEINGEPTQGITHTRAIELIQAGGNKVLLLLRPGTGLIPDHGDWDTNSPSSSNVIYDEQPPPLPSSHSASTFEESHVPATEDSLTRVQICEKAEELKDTVQEKKSTLNGSQPEMKYQSVHKTMSKKDPPRGSGHGEKSRLKGENGVTRRGRSASPKKSVNRHSEEHLEKIPRPLKSDPKEKSRDRSLSPRKGESKGRLTIKAGSGQDPYRKDRGRSSSPKKQQKIGGNSLSNTEGKLSEAGSRRAAGHPRDSTEQLPDGREKSGVSRKDLKQSQPGKTRTKSPEKKSSKVDETSLPSKKTSSTAGRVVSEKEKGKKPTAGETSRETVEHTQISAKQLKQEAQEKTALGNADDHKGRESEVTDRCRERAGCTPQSSSLVKKAPITPGPWRVPRANKVTGTTGMADKQL", "output": "Acts as a scaffolding protein at cell-cell junctions, thereby regulating various cellular and signaling processes. Cooperates with PTEN to modulate the kinase activity of AKT1. Its interaction with PTPRB and tyrosine phosphorylated proteins suggests that it may link receptor tyrosine phosphatase with its substrates at the plasma membrane. In polarized epithelial cells, involved in efficient trafficking of TGFA to the cell surface. Regulates the ability of LPAR2 to activate ERK and RhoA pathways. Regulates the JNK signaling cascade via its interaction with FZD4 and VANGL2."}]}
+{"id": "function_test_439", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MYNLSRIIYRFSSVSLNPSTRASGFLLENASSKILQSATNRAFSAKSGSDGVGGDDNGWNISTGGSFGGTGSADLDWDNKSMWSTGLTKEHFDGVSVGRQKNAANPSSDNTPSDSGDVMSKLGPKEVALVNEMNEYDDLLKEIEQDNRQGRAFVDGIKQRMMEISVLLKQVKEPGARGSYLKDSEKTEMYRLHKENPEVYTIERLAKDYRIMRQRVHAILFLKEDEEEEERKLGRPLDDSVDRLLDEYPEFFISHDREFHVASLNYKPDFKVMPEGWDGTIKDMDEVHYEISKKEDDMLYEEFVRRFEFNKMKWRGEVMCHKYSRRRSSEGWKITVEKLGAKGKRGAGGGWKFMSLPDGSSRPLNEMEKVYVKRETPLRRRSIISTEVMRYSPANQKRRSKRKQKRKERRIACLKAGKQT", "output": "Essential for fertility (male and female gametophyte functions and development) . Required for the integrity of female gametic mitochondria . Modulates male gametophyte functions, including pollen tube growth and style penetration . Involved in mitochondrial-driven cell-to-cell communication in embryo sacs during female gametes maturation (including embryogenesis initiation and endosperm development), especially for reciprocal signaling between central and egg cells which regulates reciprocal development ."}]}
+{"id": "function_test_440", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEISQRVKARLAVLTAHLAVSDTVGLEQVLPAIAPWCTSAHITAAPHGSLKGNLTIVDERTGKKYQVPVSEHGTVKAVDLKKITTGKDDKGLKLYDPGYLNTAPVRSSICYIDGDEGILRYRGYPIEELAESSTFIEVAYLLMYGNLPSQSQLADWEFTVSQHSAVPQGVLDIIQSMPHDAHPMGVLVSAMSALSIFHPDANPALSGQDIYKSKQVRDKQIVRILGKAPTIAAAAYLRTAGRPPVLPSANLSYSENFLYMLDSMGNRSYKPNPRLARVLDILFILHAEHEMNCSTAAARHLASSGVDVYTACAGAVGALYGPLHGGANEAVLKMLAEIGTAENIPDFIEGVKNRKRKMSGFGHRVYKNYDPRAKVIKKLADEVFSIVGRDPLIEVAVALEKAALSDEYFVKRKLYPNVDFYSGLIYRAMGFPPEFFTVLFAVPRMAGYLSHWRESLDDPDTRIMRPQQAYTGVWMRHYEPVRERTLSSDSDKDKFGQVSISNASRRRLAGSSAL", "output": "Peroxisomal citrate synthase required for the fatty acid respiration in seedlings, citrate being exported from peroxisomes into mitochondria during respiration of triacylglycerol (TAG). Indeed, complete respiration requires the transfer of carbon in the form of citrate from the peroxisome to the mitochondria."}]}
+{"id": "function_test_441", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLGVVELLLLGTAWLAGPARGQNETEPIVLEGKCLVVCDSNPTSDPTGTALGISVRSGSAKVAFSAIRSTNHEPSEMSNRTMIIYFDQVLVNIGNNFDSERSTFIAPRKGIYSFNFHVVKVYNRQTIQVSLMLNGWPVISAFAGDQDVTREAASNGVLIQMEKGDRAYLKLERGNLMGGWKYSTFSGFLVFPL", "output": "Required for synapse integrity and synaptic plasticity. During cerebellar synapse formation, essential for the matching and maintenance of pre- and post-synaptic elements at parallel fiber-Purkinje cell synapses, the establishment of the proper pattern of climbing fiber-Purkinje cell innervation, and induction of long-term depression at parallel fiber-Purkinje cell synapses . Plays a role as a synaptic organizer that acts bidirectionally on both pre- and post-synaptic components . On the one hand induces accumulation of synaptic vesicles in the pre-synaptic part by binding with NRXN1 and in other hand induces clustering of GRID2 and its associated proteins at the post-synaptic site through association of GRID2 . NRXN1-CBLN1-GRID2 complex directly induces parallel fiber protrusions that encapsulate spines of Purkinje cells leading to accumulation of GRID2 and synaptic vesicles . Required for CBLN3 export from the endoplasmic reticulum and secretion . NRXN1-CBLN1-GRID2 complex mediates the D-Serine-dependent long term depression signals and AMPA receptor endocytosis (By similarity). Essential for long-term maintenance but not establishment of excitatory synapses . Inhibits the formation and function of inhibitory GABAergic synapses in cerebellar Purkinje cells .; "}]}
+{"id": "function_test_442", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MASNFKKTTMASSAQRKRMSPKPELTEDQKQEIREAFDLFDADGTGTIDIKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFSDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVNEQEFLRIMKKTSLY", "output": "Plays a fundamental role in microtubule organizing center structure and function. Required for centriole duplication and correct spindle formation. Has a role in regulating cytokinesis and genome stability via cooperation with CALM1 and CCP110 (By similarity).; "}]}
+{"id": "function_test_443", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSLKAIHVSEVPSLDHFPENPSLICSSRKANNKFVVVGHRGHGMNMSQSPDLRFSALKENSILSFNAASKFPLDFIEFDVQVTRDGCPIIFHDDFIYSEEQGVVYEKRVTEVCLSEFMSYGPQRDTGKTGKPLLRKSKEGKIHKWSVATDDSFCTLQEAFEKVENPNLGFNIELKLDDNVFYSSDHLSRLLLPILQVVSDIGNDRTIIFSSFHPDAALLVRKLQTTYPVFFLTNGGTEMYHDTRRNSLEEAIKVCLEGGLQGIVSEVKGVFRNPALVNKIKESKLSLMTYGKLNNVAEAVYMQHLMGIEGVIVDHVEEITEAVREMMKPSNRDADGTKPKPNFSDRELSFLLKLIPELIQH", "output": "Hydrolyzes glycerolphosphoglycerol, glycerophosphocholine and glycerophosphoethanolamine in vitro. May be involved in release of inorganic phosphate (Pi) from phospholipids during Pi starvation."}]}
+{"id": "function_test_444", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAGKLMHALQYNSYGGGAAGLEHVQVPVPTPKSNEVCLKLEATSLNPVDWKIQKGMIRPFLPRKFPCIPATDVAGEVVEVGSGVKNFKAGDKVVAVLSHLGGGGLAEFAVATEKLTVKRPQEVGAAEAAALPVAGLTALQALTNPAGLKLDGTGKKANILVTAASGGVGHYAVQLAKLANAHVTATCGARNIEFVKSLGADEVLDYKTPEGAALKSPSGKKYDAVVHCANGIPFSVFEPNLSENGKVIDITPGPNAMWTYAVKKITMSKKQLVPLLLIPKAENLEFMVNLVKEGKVKTVIDSKHPLSKAEDAWAKSIDGHATGKIIVEP", "output": "NADPH-dependent alpha,beta-unsaturated oxoene reductase reducing the double bond of medium-chain (C9) to long-chain (C18) reactive electrophile species deriving from poly-unsaturated fatty acid peroxides. The best substrates are 13-lipoxygenase-derived gamma-ketols, but is unable to reduce the double bond of short-chain alkenals and alkenones such as acrolein, crotonaldehyde, 3-buten-2-one, 4-hexen-3-one and trans-2-hexenal, or quinones such as duroquinone, decylubiquinone, coenzyme Q0, menadione, menaquinone and phylloquinone. Can use trans-2-nonenal, trans-3-decen-2-one, 4-hydroxynonenal, 12-oxo-10(E) dodecanoate (traumatin), 4-oxononenal, trans-1,3 diphenyl-2-propenone, trans-1,4-diphenyl-2-butene-1,4-dione, 9-oxo-12,13-epoxy-(10E)-octadecenoic acid (trans-EKODE-1b), 9-hydroxy-12-oxo-10(E)-octadecenoic acid, 9-Hydroxy-12-oxo-10(E),15(Z)-octadecadienoic acid and 9,13-dihydroxy-10-oxo-11-octadecenoic acid as substrates, but has no activity with 13(R,S)-hydroperoxy-9(Z),11(E)-octadecadienoic acid (13-HPOD), 9(S),12(S),13(S)-trihydroxy-10(E)-octadecenoic acid, 13-hydroxy-12-oxo-9(Z)-octadecenoic acid, 9-oxo-10(E),12(Z)-octadecadienoic acid (9-KODE), 13-oxo-9(Z),11(E)-octadecadienoic acid (13-KODE) and 12-oxo-10,15(Z)-phytodienoic acid (12-OPDA)."}]}
+{"id": "function_test_445", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSKSLKKKSHWTSKVHESVIGRNPEGQLGFELKGGAENGQFPYLGEVKPGKVAYESGSKLVSEELLLEVNETPVAGLTIRDVLAVIKHCKDPLRLKCVKQGGIVDKDLRHYLNLRFQKGSVDHELQQIIRDNLYLRTVPCTTRPHKEGEVPGVDYIFITVEEFMELEKSGALLESGTYEDNYYGTPKPPAEPAPLLNVTDQILPGATPSAEGKRKRNKSVTNMEKASIEPPEEEEEERPVVNGNGVVITPESSEHEDKSAGASGETPSQPYPAPVYSQPEELKDQMDDTKPTKPEENEDSDPLPDNWEMAYTEKGEVYFIDHNTKTTSWLDPRLAKKAKPPEECKENELPYGWEKIDDPIYGTYYVDHINRRTQFENPVLEAKRKLQQHNMPHTELGAKPLQAPGFREKPLFTRDASQLKGTFLSTTLKKSNMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVLCRGYPLPFDPEDPANSMVPPLAIMERPPPVMVNGRHNYETYLEYISRTSQSVPDITDRPPHSLHSMPADGQLDGTYPPPVHDDNVSMASSGATQAELMTLTIVKGAQGFGFTIADSPTGQRVKQILDIQGCPGLCEGDLIVEINQQNVQNLSHTEVVDILKDCPVGSETSLIIHRGGFFSPWKTPKPMMDRWENQGSPQTSLSAPAVPQNLPFPPALHRSSFPDSTEAFDPRKPDPYELYEKSRAIYESRQQVPPRTSFRMDSSGPDYKELDVHLRRMESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYSNSNHAAPSSNASPPEGFASHSLQTSDVVIHRKENEGFGFVIISSLNRPESGATITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRIIPQEELNSPTSAPSSEKQSPMAQQHSPLAQQSPLAQPSPATPNSPVAQPAPPQPLQLQGHENSYRSEVKARQDVKPDIRQPPFTDYRQPPLDYRQPPGGDYSQPPPLDYRQHSPDTRQYPLSDYRQPQDFDYFTVDMEKGAKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIKSGGRRVRLLLKRGTGQVPEYGMVPSSLSMCMKSDKHGSPYFYLLGHPKDTTNPTPGVLPLPPPQACRK", "output": "Seems to act as a scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins (By similarity). Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth (By similarity). May play a role in regulating activin-mediated signaling in neuronal cells . Enhances the ability of PTEN to suppress AKT1 activation (By similarity). Plays a role in receptor-mediated clathrin-dependent endocytosis which is required for ciliogenesis ."}]}
+{"id": "function_test_446", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNQTAGASNNVRCPPGKGHKELVGSNPPQRNWKGIAIALLVILVICSLIVTSVILLTPAEDTSLSQKKKVTVEDLFSEDFKIHDPEAKWISNKEFIYRERKGSVILRNVETNNSTVLIEGKKIESLRAIRYEISPDKEYVLFSYNVEPVYQHSHTGYYVLSKIPHGDPQSLDPPEVSNAKLQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKSHIAHWWSPDGTRLAYATINDSRVPLMELPTYTGSVYPTVKPYHYPKAGSENPSISLHVIGLNGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKKHEDESEAWLHRQNEEPVFSKDGRKFFFVRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITSGDWDVTKILSYDEKRNKIYFLSTEDLPRRRHLYSANTVDDFNRQCLSCDLVENCTYVSASFSHNMDFFLLKCEGPGVPTVTVHNTTDKRRMFDLEANEEVQKAINDRQMPKIEYRKIEVEDYSLPMQILKPATFTDTAHYPLLLVVDGTPGSQSVTERFEVTWETVLVSSHGAVVVKCDGRGSGFQGTKLLQEVRRRLGFLEEKDQMEAVRTMLKEQYIDKTRVAVFGKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKLAHRVSALEDQQFLIIHATADEKIHFQHTAELITQLIKGKANYSLQIYPDESHYFHSVALKQHLSRSIIGFFVECFRVQDKLPTATAKEEEEED", "output": "Promotes cell surface expression of the potassium channel KCND2 . Modulates the activity and gating characteristics of the potassium channel KCND2 . Has no dipeptidyl aminopeptidase activity (By similarity)."}]}
+{"id": "function_test_447", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSASSRFIPEHRRQNYKGKGTFQADELRRRRETQQIEIRKQKREENLNKRRNLVDVQEPAEETIPLEQDKENDLELELQLPDLLKALYSDDIEAQIQATAKFRKALSKETNPPIQKVIDAGVVPRFVEFLSHENNLLKFEASWALTNVASGSSNQTHVVVEANAVPVFVSLLSSSEQDVREQAVWALGNIAGDSPMCRDHVLQCGVLEPLLNIIESNRRLSMLRNSTWTLSNMCRGKNPQPDWNSISQVIPVLSKLIYTLDEDVLVDALWAISYLSDGANEKIQAIIDAGIPRRLVELLMHPSAQVQTPALRSVGNIVTGDDVQTQVIINCGALSALLSLLSSPRDGVRKEACWTISNITAGNSSQIQYVIEANIIPPLIHLLTTADFKIQKEACWAISNATSGGARRPDQIRYLVEQGAIKPLCNLLACQDNKIIQVALDGIENILRVGELDRANNPDKINLYAVYVEDAGGMDLIHECQNSSNSEIYQKAYNIIEKFFGEEDEIEELEPETVGDTFTFGTTQEPAGDFQFSATNAEDMAM", "output": "Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope. Seems to act as a cytosolic receptor for both simple and bipartite NLS motifs. Has an essential role in mitotic chromosome condensation. Involved in nuclear protein import. Required for efficient nuclear import of both an SV40 nuclear localization signal-containing reporter protein and the pap1 component of the stress response MAP kinase pathway. Required for proper mitotic progression."}]}
+{"id": "function_test_448", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSFDAEKQLAIAAVRRASYLTEKVFNQLIKEKSAAGALTKDDKSPVTIGDFGAQAIVISMLKDAFPNDPIVGEEDSDFLRENTQTCSRVWELVQETIQHATEYKELGQIKSAEEMMSIIDQGSYHGGRNGRMWTLDPIDGTKGFLRGAQYAICLALIENGKPVVSAIGCPNLPYDFNQPETSPKGIIMSAVRNHGCFQYSLHNEKLEPVQVHMQDVQNTKDSKFCEGVEAGHSMQGTQEEIAKYLGITRGPTKMDSQAKYASLARGDGDIYLRLPTKMTFEEKIWDHAGGSLLVEEAGGVVSDMFGKPLDFGVGRTLKNNNGVIAAYKGIFEKVIEATAAVTSKDPHFQKVAQ", "output": "Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP. Regulates the flux of sulfur in the sulfur-activation pathway by converting PAPS to APS.; "}]}
+{"id": "function_test_449", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLAAKNILNRSSLSSSFRIATRLQSTKVQGSVIGIDLGTTNSAVAIMEGKVPKIIENAEGSRTTPSVVAFTKEGERLVGIPAKRQAVVNPENTLFATKRLIGRRFEDAEVQRDIKQVPYKIVKHSNGDAWVEARGQTYSPAQIGGFVLNKMKETAEAYLGKPVKNAVVTVPAYFNDSQRQATKDAGQIVGLNVLRVVNEPTAAALAYGLEKSDSKVVAVFDLGGGTFDISILDIDNGVFEVKSTNGDTHLGGEDFDIYLLREIVSRFKTETGIDLENDRMAIQRIREAAEKAKIELSSTVSTEINLPFITADASGPKHINMKFSRAQFETLTAPLVKRTVDPVKKALKDAGLSTSDISEVLLVGGMSRMPKVVETVKSLFGKDPSKAVNPDEAVAIGAAVQGAVLSGEVTDVLLLDVTPLSLGIETLGGVFTRLIPRNTTIPTKKSQIFSTAAAGQTSVEIRVFQGERELVRDNKLIGNFTLAGIPPAPKGVPQIEVTFDIDADGIINVSARDKATNKDSSITVAGSSGLSENEIEQMVNDAEKFKSQDEARKQAIETANKADQLANDTENSLKEFEGKVDKAEAQKVRDQITSLKELVARVQGGEEVNAEELKTKTEELQTSSMKLFEQLYKNDSNNNNNNNNGNNAESDETKQ", "output": "Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Constitutes the ATP-driven core of the motor and binds the precursor preprotein. Required for the import of the processed frataxin homolog YFH1 into the mitochondrion (By similarity).; "}]}
+{"id": "function_test_450", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKVLWAALLVTFLAGCQAKVEQPVESEPEPELRQQTEWQSGQPWELALGRFWDYLRWVQTLSEQVQEELLSSQVTQELTTLMDETMKELKAYKSDLEEQLSPVAEETRARLSKELQAAQARLGADMEDVRSRLVQYRGEVQAMLGQSTEELRARLASHLRKLRKRLLRDADDLQKRLAVYQAGAREGAERGVSAIRERLGPLVEQGRVRAATVGSLAGQPLQERAQAWGERLRARMEEVGSRTRDRLDEVKEQVAEVRAKLEEQAQQISLQAEAFQARLKSWFEPLVEDMQRQWAGLVEKVQAAVGASTAPVPSDNH", "output": "APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apolipoproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density lipoproteins (IDL) but shows a preferential binding to high-density lipoproteins (HDL). It also binds a wide range of cellular receptors including the LDL receptor/LDLR, the LDL receptor-related proteins LRP1, LRP2 and LRP8 and the very low-density lipoprotein receptor/VLDLR that mediate the cellular uptake of the APOE-containing lipoprotein particles. Finally, APOE has also a heparin-binding activity and binds heparan-sulfate proteoglycans on the surface of cells, a property that supports the capture and the receptor-mediated uptake of APOE-containing lipoproteins by cells. A main function of APOE is to mediate lipoprotein clearance through the uptake of chylomicrons, VLDLs, and HDLs by hepatocytes. APOE is also involved in the biosynthesis by the liver of VLDLs as well as their uptake by peripheral tissues ensuring the delivery of triglycerides and energy storage in muscle, heart and adipose tissues. By participating in the lipoprotein-mediated distribution of lipids among tissues, APOE plays a critical role in plasma and tissues lipid homeostasis. APOE is also involved in two steps of reverse cholesterol transport, the HDLs-mediated transport of cholesterol from peripheral tissues to the liver, and thereby plays an important role in cholesterol homeostasis. First, it is functionally associated with ABCA1 in the biogenesis of HDLs in tissues. Second, it is enriched in circulating HDLs and mediates their uptake by hepatocytes. APOE also plays an important role in lipid transport in the central nervous system, regulating neuron survival and sprouting."}]}
+{"id": "function_test_451", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDPYKHRPSSGSNSSFWTTNSGAPVWNNNSALTVGQRGPILLEDYHLIEKLAQFDRERIPERVVHARGASAKGFFEVTHDVSHLTCADFLRAPGVQTPVIVRFSTVVHERGSPETLRDPRGFAVKFYTREGNFDLVGNNMPVFFIRDGMKFPDMVHAFKPNPKTNLQENWRIVDFFSHHPESLHMFTFLFDDVGIPLNYRHMEGFGVNTYSLINRDGKPHLVKFHWKPTCGVKCLLDNEAVTVGGTCHSHATKDLYDSIAAGNYPEWKLYIQTIDLDHEDKFDFDPLDVTKTWPEDIIPLQPVGRMVLNKNVDNFFAENEQIAFCPAISVPAIHYSDDKLLQTRIFSYADTQRHRLGPNYLMLPVNAPKCAHHNNHHDGFMNFMHRDEEVNYFPSRFDPARHAEKVPIPPRVLTRCREKCIIQKENNFKQAGERYRSFDPARQDRFIQRWVDALTHPRVTHEHRTIWISYWSQCDAALGQKLPSRLNLKPSM", "output": "Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide."}]}
+{"id": "function_test_452", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGARASVLSGGELDRWEKIRLRPGGKKKYRLKHIVWASRELERFAVNPGLLESSEGCRQILGQLQPSLKTGSEELTSLYNTVATLYCVHQRIEIKDTKEALEKIEEEQTKSMKKAQQAAADTGNSSQVSQNYPIVQNLQGQMVHQAISPRTLNAWVKVIEEKAFSPEVIPMFSALSEGATPQDLNTMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHAGPIAPGQMREPRGSDIAGTTSTLQEQIGWMTNNPPIPVGEIYKRWIILGLNKIVRMYSPVSILDIRQGPKEPFRDYVDRFYKTLRAEQATQEVKNWMTETLLVQNANPDCKTILKALGPAATLEEMMTACQGVGGPGHKARVLAEAMSQVTNPATIMMQRGNFRNQRKNVKCFNCGKEGHIARNCRAPRKKGCWKCGKEGHQMKECTERQANFLREDLAFLQGKAREFPSEQTRANSPTRRELQVWGRDSNSLSEAGAEAGADRQGIVSFNFPQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDMDLPGRWKPKMIGGIGGFIKVRQYDQIPIDICGHKAVGTVLVGPTPVNIIGRNLLTQIGCTLNFPISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKLVDFRELNRRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIIIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTEVIPLTKEAELELAENREILKEPVHGVYYDPSKDLIVEIQKQGQGQWTYQIFQEPFKNLKTGKYARTRGAHTNDVKQLTEAVQKIANESIVIWGKIPKFKLPIQKETWETWWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIVGAETFYVDGAANRETKLGKAGYVTSRGRQKVVSLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDKLVSAGIRKVLFLDGIDKAQEDHEKYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGIWQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVTTIHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDNRDPIWKGPAKLLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED", "output": "[Gag-Pol polyprotein]: Mediates, with Gag polyprotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical particles, recruiting the viral Env proteins, and packaging the genomic RNA via direct interactions with the RNA packaging sequence (Psi). Gag-Pol polyprotein may regulate its own translation, by the binding genomic RNA in the 5'-UTR. At low concentration, the polyprotein would promote translation, whereas at high concentration, the polyprotein would encapsidate genomic RNA and then shut off translation.; "}]}
+{"id": "function_test_453", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGDMANNSVAYGGVKNSLKEANHDGDFGITLADVRALMELRSTDALRKIQESYGDVYGICTRLKTSPVEGLSGNPADIERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGDNALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGINSQTGIIFTLLGAGGEEEEKKDEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKSVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKIPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPEPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSGRNAPLHAPPSEHYTIVFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVVQIIIVQFGGKPFSCSELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKEEIPEEELAEDVEEIDHAERELRRGQILWFRGLNRIQTQIRVVNAFRSSLYEGLEKPESRSSIHNFMTHPEFRIEDSEPHIPLIDDTDAEDDAPTKRNCSPPPSPNKNNNAVDSGIYLTIEMNKSATSSSPGSPLHSLETSL", "output": "Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellular calcium homeostasis. Plays a role in blood pressure regulation through regulation of intracellular calcium concentration and nitric oxide production leading to regulation of vascular smooth muscle cells vasoconstriction. Positively regulates bone mineralization through absorption of calcium from the intestine. Plays dual roles in osteoclast differentiation and survival by regulating RANKL-induced calcium oscillations in preosteoclasts and mediating calcium extrusion in mature osteoclasts (By similarity). Regulates insulin sensitivity through calcium/calmodulin signaling pathway by regulating AKT1 activation and NOS3 activation in endothelial cells (By similarity). May play a role in synaptic transmission by modulating calcium and proton dynamics at the synaptic vesicles."}]}
+{"id": "function_test_454", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAMRTPEELSNLIKDLIEQYTPEVKMVDFGIVFQVGDGIARIYGLEKAMSGELLEFEDGTLGIALNLEANNVGAVLLGDGLKITEGSRVRCTGKIAEIPVGEAYLGRVVDGLARPVDGKGAVQTKDSRAIESPAPGIVARRSVYEPLATGLVAVDAMIPVGRGQRELIIGDRQTGKTAIAVDTILNQKGKGVICVYVAIGQKASSVAQVLNTLKERGALDYTIIVMANANEPATLQYLAPYTGATLAEYFMYTGRPTLTIYDDLSKQAQAYREMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLNNALGEGSMTALPIVETQEGDVSAYIPTNVISITDGQIFLAAGLFNSGLRPAINVGISVSRVGSAAQPKAMKQVAGKLKLELAQFAELEAFSQFASDLDQATQNQLARGARLREILKQPQSSPLSVEEQVASLYAGTNGYLDKLEVSQVRAYLSGLRSYLANSYPKYGEILRSTLTFTPEAEGLVKQAINEYLEEFKSQAKAA", "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "}]}
+{"id": "function_test_455", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MFPYPTLNYPPMAPINPMAYRDPNPPRQVAPFRPPLAAQIEDLRRSIANLTLKQRAPNPPAGPPAKRKKPAPKPKPAQAKKKRPPPPAKKQKRKPKPGKRQRMCMKLESDKTFPIMLNGQVNGYACVVGGRVFKPLHVEGRIDNEQLAAIKLKKASIYDLEYGDVPQCMKSDTLQYTSDKPPGFYNWHHGAVQYENNRFTVPRGVGGKGDSGRPILDNKGRVVAIVLGGVNEGSRTALSVVTWNQKGVTVKDTPEGSEPWSLATVMCVLANITFPCDQPPCMPCCYEKNPHETLTMLEQNYDSRAYDQLLDAAVKCNARRTRRDLDTHFTQYKLARPYIADCPNCGHSRCDSPIAIEEVRGDAHAGVIRIQTSAMFGLKTDGVDLAYMSFMNGKTQKSIKIDNLHVRTSAPCSLVSHHGYYILAQCPPGDTVTVGFHDGPNRHTCTVAHKVEFRPVGREKYRHPPEHGVELPCNRYTHKRADQGHYVEMHQPGLVADHSLLSIHSAKVKITVPSGAQVKYYCKCPDVREGITSSDHTTTCTDVKQCRAYLIGNKKWVYNSGRLPRGEGDTFKGKLHVPFVPVKAKCIATLAPEPLVEHKHRTLILHLHPDHPTLLTTRSLGSDANPTRQWIERPTTVNFTVTGEGLEYTWGNHPPKRVWAQESGEGNPHGWPHEVVVYYYNRYPLTTIIGLCTCVAIIMVSCVHPCGSFAGLRNLCITPYKLAPNAQVPILLALLCCIKPTRADDTLQVLNYLWNNNQNFFWMQTLIPLAALIVCMRIVRCLFCCGPAFLLVCGAWAAAYEHTAVMPNKVGIPYKALVERPGYAPVHLQIQLVNTSIIPSTNLEYITCKYKTKVPSPVVKCCGATQCTSKPHPDYQCQVFTGVYPFMWGGAYCFCDTENTQMSEAYVERSEECSIDHAKAYKVHTGTVQAMVNITYGSVSWRSADVYVNGETPAKIGDAKLIIGPLSSAWSPFDNKVVVYGHEVYNYDFPEYGTGKAGSFGDLQSRTSTSNDLYANTNLKLQRPQAGIVHTPFTQAPSGFERWKRDKGAPLNDVAPFGCSIALEPLRAENCAVGSIPISIDIPDAAFTRISETPTVSDLECKITECTYASDFGGIATLPTNPVKQETVQFILHQVLQLLKRMTSPLLRAGSFTFHFSTANIHPAFKLQVCTSGVTCKGDCKPPKDHIVDYPAQHTESFTSAISATAWSWLKVLVGGTSAFIVLGLIATAVVALVLFFHRH", "output": "[Capsid protein]: Forms an icosahedral capsid with a T=4 symmetry composed of 240 copies of the capsid protein surrounded by a lipid membrane through which penetrate 80 spikes composed of trimers of E1-E2 heterodimers (By similarity). The capsid protein binds to the viral RNA genome at a site adjacent to a ribosome binding site for viral genome translation following genome release . Possesses a protease activity that results in its autocatalytic cleavage from the nascent structural protein (By similarity). Following its self-cleavage, the capsid protein transiently associates with ribosomes, and within several minutes the protein binds to viral RNA and rapidly assembles into icosahedric core particles (By similarity). The resulting nucleocapsid eventually associates with the cytoplasmic domain of the spike glycoprotein E2 at the cell membrane, leading to budding and formation of mature virions (By similarity). In case of infection, new virions attach to target cells and after clathrin-mediated endocytosis their membrane fuses with the host endosomal membrane (By similarity). This leads to the release of the nucleocapsid into the cytoplasm, followed by an uncoating event necessary for the genomic RNA to become accessible (By similarity). The uncoating might be triggered by the interaction of capsid proteins with ribosomes (By similarity). Binding of ribosomes would release the genomic RNA since the same region is genomic RNA-binding and ribosome-binding (By similarity). Specifically inhibits interleukin-1 receptor-associated kinase 1/IRAK1-dependent signaling during viral entry, representing a means by which the alphaviruses may evade innate immune detection and activation prior to viral gene expression (By similarity). Inhibits host transcription (By similarity). Forms a tetrameric complex with XPO1/CRM1 and the nuclear import receptor importin (By similarity). This complex blocks the central channel of host nuclear pores thereby inhibiting the receptor-mediated nuclear transport and thus the host mRNA and rRNA transcription (By similarity). The inhibition of transcription is linked to a cytopathic effect on the host cell (By similarity).; "}]}
+{"id": "function_test_456", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKPSPQFFLAAFLSLILQTGICYGIKWIALSKTPSSLALNQTQHCKQLEGLVVSQVQLCRSNLELMQTIIQAAREVIKTCRKTFSDMRWNCSSIELAPNYLLDLERGTRESAFVYALSAAAISHTIARACTTGDLPGCSCGPIPGETPGPGYRWGGCADNLNYGLIMGSKFSDAPMKMKKSGSQANKLMHLHNSEVGRQVLKASLEMKCKCHGVSGSCSIKTCWKGLQELRDIALDLKNKYLSATKVVHRPMGTRKYLVPKDIDIRPVKETELIYLQSSPDFCMKNEKVGSHGTQDRQCNKTSNGSDSCDLMCCGRGYNPYMDKVVERCHCKYHWCCYVTCKKCERTVERYVCK", "output": "Ligand for members of the frizzled family of seven transmembrane receptors. May play a role in the formation of dermal structure, both limb and feather buds. Is likely to signal over only few cell diameters."}]}
+{"id": "function_test_457", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCDQGYEVIVEQQIAHELQLKNVPTGTLAEIGQQADLAVVVGGDGNMLGAARTLARYDINVIGINRGNLGFLTDLDPDNALQQLSDVLEGRYISEKRFLLEAQVCQQDRQKRISTAINEVVLHPGKVAHMIEFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRSDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKLF", "output": "Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. It can use ATP and other nucleoside triphosphates as a source of phosphorus. NADH cannot replace NAD as a substrate."}]}
+{"id": "function_test_458", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKMKSIYFIAGLLLMIVQGSWQNPLQDTEEKSRSFKASQSEPLDESRQLNEVKRHSQGTFTSDYSKYLDSRRAQDFVQWLMSTKRNGQQGQEDKENDKFPDQLSSNAISKRHSEFERHAEGTYTSDITSYLEGQAAKEFIAWLVNGRGRRDFPEKALMAEEMGRRHADGTFTSDINKILDDMAAKEFLKWLINTKVTQRDLLGEYQ", "output": "[Glucagon]: Plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis.; "}]}
+{"id": "function_test_459", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKAATQARIDDSPLAWLDAVQRQRHEAGLRRCLRPRPAVATELDLASNDYLGLSRHPAVIDGGVQALRIWGAGATGSRLVTGDTKLHQQFEAELAEFVGAAAGLLFSSGYTANLGAVVGLSGPGSLLVSDARSHASLVDACRLSRARVVVTPHRDVDAVDAALRSRDEQRAVVVTDSVFSADGSLAPVRELLEVCRRHGALLLVDEAHGLGVRGGGRGLLYELGLAGAPDVVMTTTLSKALGSQGGVVLGPTPVRAHLIDAARPFIFDTGLAPAAVGAARAALRVLQAEPWRPQAVLNHAGELARMCGVAAVPDSAMVSVILGEPESAVAAAAACLDAGVKVGCFRPPTVPAGTSRLRLTARASLNAGELELARRVLTDVLAVARR", "output": "Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide (By similarity). Can also use pimeloyl-CoA instead of pimeloyl-ACP as substrate. To a lesser extent, can also utilize D-alanine instead of L-alanine as substrate."}]}
+{"id": "function_test_460", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKVLIFALLFSLAKAQEGCGIISRKPQPKMEKVSSSRRGVYYNDDIFRSDVLHLTQDYFLPFDSNLTQYFSLNIDSNKYTYFDNPILDFGDGVYFAATEKSNVIRGWIFGSSFDNTTQSAIIVNNSTHIIIRVCNFNLCKEPMYTVSKGTQQSSWVYQSAFNCTYDRVEKSFQLDTAPKTGNFKDLREYVFKNRDGFLSVYQTYTAVNLPRGFPAGFSVLRPILKLPFGINITSYRVVMTMFSQFNSNFLPESAAYYVGNLKYTTFMLSFNENGTITDAVDCSQNPLAELKCTIKNFNVSKGIYQTSNFRVTPTQEVVRFPNITNRCPFDKVFNASRFPNVYAWERTKISDCVADYTVLYNSTSFSTFKCYGVSPSKLIDLCFTSVYADTFLIRSSEVRQVAPGETGVIADYNYKLPDDFTGCVIAWNTAQQDQGQYYYRSYRKEKLKPFERDLSSDENGVYTLSTYDFYPSIPVEYQATRVVVLSFELLNAPATVCGPKLSTQLVKNQCVNFNFNGLRGTGVLTTSSKRFQSFQQFGRDTSDFTDSVRDPQTLEILDISPCSFGGVSVITPGTNASSEVAVLYQDVNCTDVPTSIHADQLTPAWRVYSTGVNVFQTQAGCLIGAEHVNASYECDIPIGAGICASYHTASVLRSTGQKSIVAYTMSLGAENSIAYANNSIAIPTNFSISVTTEVMPVSIAKTSVDCTMYICGDSLECSNLLLQYGSFCTQLNRALTGIAIEQDKNTQEVFAQVKQMYKTPAIKDFGGFNFSQILPDPSKPTKRSFIEDLLFNKVTLADAGFMKQYGECLGDISARDLICAQKFNGLTVLPPLLTDEMIAAYTAALVSGTATAGWTFGAGSALQIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFNKAISQIQESLTTTSTALGKLQDVVNDNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQAAPHGVVFLHVTYVPSQERNFTTAPAICHEGKAYFPREGVFVSNGTSWFITQRNFYSPQIITTDNTFVAGNCDVVIGIINNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYVWLGFIAGLIAIVMVTILLCCMTSCCSCLKGACSCGSCCKFDEDDSEPVLKGVKLHYT", "output": "[Spike protein S1]: Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection.; "}]}
+{"id": "function_test_461", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGQPGNRSVFLLAPNGSHAPDQDVPQERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMKMWTFGSFWCEFWISIDVLCVTASIETLCVIAVDRYLAITSPFKYQCLLTKNKARVVILMVWVVSGLISFLPIKMHWYQATHREALNCYAEEACCDFFTNQPYAIASSIVSFYLPLVVMVFVYSRVFQVARRQLQKIDKSEGRFHAQNLSQAEQDGRSGPGHRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHGIHDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRMAFQELLCLHRSSLKAYGNGCSSNSNGRTDYTGEQSGCYLGEEKDSERLCEDAPGPEGCAHRQGTVPDDSTDSQGRNCSTNDSML", "output": "Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine (By similarity)."}]}
+{"id": "function_test_462", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSASSLLEQRPKGQGNKVQNGSVHQKDGLNDDDFEPYLSPQARPNNAYTAMSDSYLPSYYSPSIGFSYSLGEAAWSTGGDTAMPYLTSYGQLSNGEPHFLPDAMFGQPGALGSTPFLGQHGFNFFPSGIDFSAWGNNSSQGQSTQSSGYSSNYAYAPSSLGGAMIDGQSAFANETLNKAPGMNTIDQGMAALKLGSTEVASNVPKVVGSAVGSGSITSNIVASNSLPPATIAPPKPASWADIASKPAKQQPKLKTKNGIAGSSLPPPPIKHNMDIGTWDNKGPVAKAPSQALVQNIGQPTQGSPQHVGQQANNSPPVAQASVGQQTQPLPPPPPQPAQLSVQQQAAQPTRWVAPRNRGSGFGHNGVDGNGVGQSQAGSGSTPSEPHPVLEKLRSINNYNPKDFDWNLKHGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGPVYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVWSQDKWKGRFDVRWIFVKDVPNSQLRHIRLENNENKPVTNSRDTQEVPLEKAKQVLKIIASYKHTTSIFDDFSHYEKRQEEEESVKKERQGRGK", "output": "Specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs, and regulates their stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing. Acts as a regulator of mRNA stability by promoting degradation of m6A-containing mRNAs via interaction with the CCR4-NOT and ribonuclease P/MRP complexes, depending on the context. The YTHDF paralogs (YTHDF1, YTHDF2 and YTHDF3) share m6A-containing mRNAs targets and act redundantly to mediate mRNA degradation and cellular differentiation. M6A-containing mRNAs containing a binding site for RIDA/HRSP12 (5'-GGUUC-3') are preferentially degraded by endoribonucleolytic cleavage: cooperative binding of RIDA/HRSP12 and YTHDF2 to transcripts leads to recruitment of the ribonuclease P/MRP complex. Other m6A-containing mRNAs undergo deadenylation via direct interaction between YTHDF2 and CNOT1, leading to recruitment of the CCR4-NOT and subsequent deadenylation of m6A-containing mRNAs (By similarity). Required maternally to regulate oocyte maturation: probably acts by binding to m6A-containing mRNAs, thereby regulating maternal transcript dosage during oocyte maturation, which is essential for the competence of oocytes to sustain early zygotic development. Also required during spermatogenesis: regulates spermagonial adhesion by promoting degradation of m6A-containing transcripts coding for matrix metallopeptidases (By similarity). Also involved in hematopoietic stem cells specification by binding to m6A-containing mRNAs, leading to promote their degradation (By similarity). Also acts as a regulator of neural development by promoting m6A-dependent degradation of neural development-related mRNA targets (By similarity). Inhibits neural specification of induced pluripotent stem cells by binding to methylated neural-specific mRNAs and promoting their degradation, thereby restraining neural differentiation. Regulates circadian regulation of hepatic lipid metabolism: acts by promoting m6A-dependent degradation of PPARA transcripts. Regulates the innate immune response to infection by inhibiting the type I interferon response: acts by binding to m6A-containing IFNB transcripts and promoting their degradation. May also act as a promoter of cap-independent mRNA translation following heat shock stress: upon stress, relocalizes to the nucleus and specifically binds mRNAs with some m6A methylation mark at their 5'-UTR, protecting demethylation of mRNAs by FTO, thereby promoting cap-independent mRNA translation. Regulates mitotic entry by promoting the phase-specific m6A-dependent degradation of WEE1 transcripts. Promotes formation of phase-separated membraneless compartments, such as P-bodies or stress granules, by undergoing liquid-liquid phase separation upon binding to mRNAs containing multiple m6A-modified residues: polymethylated mRNAs act as a multivalent scaffold for the binding of YTHDF proteins, juxtaposing their disordered regions and thereby leading to phase separation. The resulting mRNA-YTHDF complexes then partition into different endogenous phase-separated membraneless compartments, such as P-bodies, stress granules or neuronal RNA granules. May also recognize and bind RNAs modified by C5-methylcytosine (m5C) and act as a regulator of rRNA processing (By similarity)."}]}
+{"id": "function_test_463", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSGYSSDRDRGRDRGFGAPRFGGSRAGPLSGKKFGNPGEKLVKKKWNLDELPKFEKNFYQEHPDLARRTAQEVETYRRSKEITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERGWVLNEFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQAINPKLLQLVEDRGSGRSRGRGGMKDDRRDRYSAGKRGGFNTFRDRENYDRGYSSLLKRDFGAKTQNGVYSAANYTNGSFGSNFVSAGIQTSFRTGNPTGTYQNGYDSTQQYGSNVPNMHNGMNQQAYAYPATAAAPMIGYPMPTGYSQ", "output": "Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre-mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 transcriptional activity and involved in skeletal muscle differentiation. Transcriptional coactivator for p53/TP53 and involved in p53/TP53 transcriptional response to DNA damage and p53/TP53-dependent apoptosis. Transcriptional coactivator for RUNX2 and involved in regulation of osteoblast differentiation. Acts as transcriptional repressor in a promoter-specific manner; the function probably involves association with histone deacetylases, such as HDAC1. As component of a large PER complex is involved in the inhibition of 3' transcriptional termination of circadian target genes such as PER1 and NR1D1 and the control of the circadian rhythms (By similarity)."}]}
+{"id": "function_test_464", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKLQGSRMWLCPRTRLPVGASALGFLILCWLYVFPGYRLPGHKEMVREVLRFGPGWRKNRTEMDSFRKLLQDCCDPPHLFSLTKVNTPLGENLWFDGEFFHSLTIDNSTRSLFPQDTPFKLPLKRCSVVGNGGILKNSRCGEQIDEADFVMRCNLPPLSREYTEDVGTRTQLVTVNPSIIDKRYQNLLWSRKSFVENLRVYQQSYVYMPAFSTKRGTDPSLRVYYTLADFGTNQTVLFANPNFLRNVGKFWKSRGIHSKRLSTGLFMVSAALSLCEEVTIYGFWPFQMDLGGRYISHHYYDNTLPLSGVHAMPEEFLQLWLLHKSGVLQMQLDQCKKDVSSQKPH", "output": "Catalyzes the addition of sialic acid in alpha 2,8-linkage to the sialic acid moiety of the ganglioside GM3 to form ganglioside GD3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid (By similarity). Glycosphingolipids are required for convergence extension movements during early development (By similarity). Can catalyze the addition of a second alpha-2,8- sialic acid to GD3 to form GT3 (By similarity). Can use GM1b, GD1a and GT1b as acceptor substrates to synthesize GD1c, GT1a and GQ1b respectively (By similarity)."}]}
+{"id": "function_test_465", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRYLVISLFAVSLLMAGSALVGNAADAAKAPKKAIELKHGTSKRMHVMFNHTTHKDIACEQCHHDSPAPDKPYASCTDNDCHATPGPRERDTMSMFVAYHAKDTDRSCYGCHKKMAAQHPEFTGCRPCHMSQQARKEAAASEKK", "output": "Participates in sulfate respiration coupled with phosphorylation by transferring electrons from the enzyme dehydrogenase to ferredoxin (By similarity). Gamma chain of the formate dehydrogenase (FDH) that catalyzes the reversible two-electron oxidation of formate to carbon dioxide. The gamma subunit of formate dehydrogenase forms a c-type heme."}]}
+{"id": "function_test_466", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSARTWRVVLGEHNLNTNEGKEQIMTVNSVFIHSGWNSDDVAGGYDIALLRLNTQASLNSAVQLAALPPSNQILPNNNPCYITGWGKTSTGGPLSDSLKQAWLPSVDHATCSSSGWWGSTVKTTMVCAGGGANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAYISWMNGIM", "output": "Acts upon elastin."}]}
+{"id": "function_test_467", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MMNMKIVLFSLLLFVIRWNIISCNKNDKNQGVDMNVLNNYENLFKFVKCEYCNEHTYVKGKKAPSDPQCADIKEECKELLKEKQYTDSVTYLMDGFKSANNSANNGKKNNAEEMKNLVNFLQSHKKLIKALKKNIESIQNKKHLIYKNKSYNPLLLSCVKKMNMLKENVDYIQKNQNLFKELMNQKATYSFVNTKKKIISLKSQGHKKETSQNQNENNDNQKYQEVNDEDDVNDEEDTNDDEDTNDEEDTNDDEDTNDDEDTNDEEDTNDEEDHENNNATAYELGIVPVNDVLNVNMKNMITGNNFMDVVKNTLAQSGGLGSNDLINFLNQGKEIGENLLNITKMNLGDKNNLESFPLDELNMLKDNLINYEFILDNLKTSVLNKLKDLLLRLLYKAYVSYKKRKAQEKGLPEPTVTNEEYVEELKKGILDMGIKLLFSKVKSLLKKLKNKIFPKKKEDNQAVDTKSMEEPKVKAQPALRGVEPTEDSNIMNSINNVMDEIDFFEKELIENNNTPNVVPPTQSKKKNKNETVSGMDENFDNHPENYFKEEYYYDENDDMEVKVKKIGVTLKKFEPLKNGNVSETIKLIHLGNKDKKHIEAINNDIQIIKQELQAIYNELMNYTNGNKNIQQIFQQNILENDVLNQETEEEMEKQVEAITKQIEAEVDALAPKNKEEEEKEKEKEEKEKEEKEKEKEEKEKEEKEKEEKEKEEKEEEKKEKEEEQEEEEEEEIVPENLTTEESK", "output": "During the asexual blood stage, involved in the sialic acid-independent (SAID) merozoite invasion of host erythrocytes by binding to host SLC4A1/Band 3 protein on the surface of the host erythrocyte."}]}
+{"id": "function_test_468", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSSKEKGKFEDMAKADKLRYEKEMKNYVPPKGETKKKFKDPNAPKRPPSAFFLFCSEFRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKVDAGKKVVAKAEKSKKKKEEEEDEDEDEEDEEDEEEEEEEEEDDDDDE", "output": "Multifunctional redox sensitive protein with various roles in different cellular compartments. Nuclear functions are attributed to fully reduced HGMB1. Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA, DNA-containing cruciforms or bent structures, supercoiled DNA and ZDNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters. Can restructure the canonical nucleosome. Proposed to be an universal biosensor for nucleic acids. May promote inflammatory response to sterile and infectious signals and may be involved in the coordination and integration of innate and adaptive immune responses. In the cytoplasm may function as sensor and/or chaperone for immunogenic nucleic acids, and mediate autophagy. May act as danger associated molecular pattern (DAMP) molecule that amplifies immune responses during tissue injury."}]}
+{"id": "function_test_469", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDKLVSILVPCYKSKPFLKRFFNSLLKQDLNQAKIIFFNDNVADETYEVLQKFKKEHNNLAIEVYCDKQNEGIGKVRDKLVNLVTTPYFYFIDPDDCFNNKNVIKEIVESIKKEDFDLGVLKSMVYLCFLKHDFIIKFLPLKGIFQGRVKLINNNNVNKLNYIKNNDQYIWNIVINTDFFRKLNLTFESRLFEDIPIWYPMFFSSQKIVFIDVIGTNYFIRNDSLSTTISAPRYLNLIQCYEKLYVNLSQNGSLASFIDPNHKIEARFWRRQMFVWFALFSFEYFKKNFSESKKILEKLFVFLEKNGVYERVFQTKNQGIYYIWVQRLKYFKHVLESKSDN", "output": "Processive glycosyltransferase involved in the biosynthesis of both the non-bilayer-prone beta-monoglycosyldiacylglycerol and the bilayer-forming membrane lipid beta-diglycosyldiacylglycerol. These components contribute to regulate the properties and stability of the membrane. Catalyzes sequentially the transfers of glucosyl or galactosyl residues from UDP-Glc or UDP-Gal to diacylglycerol (DAG) acceptor to form the corresponding beta-glycosyl-DAG (3-O-(beta-D-glycopyranosyl)-1,2-diacyl-sn-glycerol), which then acts as acceptor to give beta-diglycosyl-DAG product (3-O-(beta-D-glycopyranosyl-beta-(1->6)-D-glycopyranosyl)-1,2-diacyl-sn-glycerol). Dioleoylglycerol (DOG) is a preferred sugar acceptor than 3-O-(beta-D-glucopyranosyl)-1,2-dioleoyl-sn-glycerol."}]}
+{"id": "function_test_470", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MYSEGKLLKVFLIFAGFIIFSLCGEVVSQRYPPAPGLLKYLEQDVCYSLYYYLNWTSLADCKTNFEETGISDVPSTVKVRCQSKNSIRFETEPSEHWQLFILMEHDNFDPIPFTLIEPNNVFGELITTANKEYQIWSTYLDEYGTLQDWMEGPIVLKFDQRNQQPDDIKYNVTQEFKYIILGNDSYTINGKFVWNTTGDRDLCFDIANICQNTNMKHAKIWPTAHPSFDVENLVLNDECEIHVKGIHGTTKHKYKTPSCFELPECFLNNMEPEIPQDVAIAADQDLRGWWNINVAWAKPHFQPEIYNVTVRANMIRSIILPGNATETTFRNIPNTFLSAGKIYNVSVYAIIGQKASHTSRRAFTPGMLRWVWAGATAGAGCAAGGLLAATLLCCGHRRATSRVSQEDPDEKTPKEDDVEIIGIESGSADDHWEVRSDRVLLHEVIGEGAFGVVRRGTLAPGGKSVAVKMLKEFPSQEEVRSFRSEMELMKSVGAHPHVVSLVGCCSGRKPLIVAEYCSRGDLLSYLRSSWDIIVSKHTAKYYNNNMDSMDTSKLKVHKEHTKLVVNKLYELQGPCETELTPLDLLSFCRQIAMGMEFLASNRIVHRDLAARNVLVTEDKTLKIADFGLSRDIYEENQYKQKGNGKMPVKWMALESLTRRVYTTQSDVWSFGVVIWEIVTVGGSPYPEVPAARLVRSLRSGYRMPKPVNCSKPLYDIMRACWNASPRDRPTFPELHQKLDDLLHSACANEYITLEVDVDEAPSTPKPQRYIKMLIRGKLPWSRESYERPVNPTSNLYSSPPVIQTKTA", "output": "Probable receptor tyrosine kinase. During postembryonic development, involved in the initiation of metamorphosis probably by inducing the production of ecdysone in response to prothoracicotropic hormone (PTTH) (By similarity). Binding to PTTH stimulates activation of canonical MAPK signaling leading to ERK phosphorylation ."}]}
+{"id": "function_test_471", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSLMFLRRAGNIKGRNIRFALQRGSVGYSQQSSEACKNFLNTTQLRTMVQTAALHGPKPMDSSHIKVTNVKELKPLPEWKSLKFGENFTDHMLIMKWNREKGWSTPEIVPFGKLCFHPASSVFHYGFECFEGMKAFRDEKGVPRLFRPIKNAERMLSTGTRISLPSFDPAELAEIIRKFVAHENRWVPDQRGYSLYIRPTFIGTDEALGVHHCDNAMLYVIASPVGPYYSSGFKAVKLCCSEESVRAWPGGTGHYKLGGNYAPSVLPQKEAAKKGYAQILWLYGDEDYITEVGTMNCFTVWINKNGEKEIITAPLDGMILPGVTRDSILEICRERLAPKGWKITEGKYSMKEVAQASKEGRLLEVFGAGTAALVSPVKAINYKGTEYEIPMPEGQEAGPITSEISKWILDIQYGKEPNNPWSVPALP", "output": "Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine."}]}
+{"id": "function_test_472", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLREYKLVVVGGGGVGKSALTIQLIQSHFVDEYDPTIEDSYRKQCTIDDQQVLLDVLDTAGQEEYSAMREQYMRTGEGFLLVYSINSLNSFQELNSFYDQILRVKDSDNVPVLVVGNKCDLEMERQVSYEDGLALANSFNCPFLETSAKQRINVEEAFYGLVRNINQYNAKIAEAEKQQQQQQQQQNANQQGQDQYGQQKDNQQSQFNNQINNNNNTSAVNGGVSSDGIIDQNGNGGVSSGQANLPNQSQSQSQRQQQQQQQEPQQQSENQFSGQKQSSSKSKNGCCVIV", "output": "Required for the regulation of both a MAP kinase signaling pathway and a cAMP signaling pathway. The activation of these pathways contributes to the pathogenicity of the cells through the induction of the morphological transition from the yeast to the polarized filamentous form (By similarity)."}]}
+{"id": "function_test_473", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIEVLLVTICLAVFPYPGSSIILESGNVDDYEVVYPQKLTALPKGAVQPKYEDAMQYEFKVNGEPVVLHLEKNKGLFSEDYSETHYSPDGREITTYPSVEDHCYYHGRIQNDADSTASISACDGLKGYFKLQGETYLIEPLELSDSEAHAVFKYENVEKEDEAPKMCGVTQNWESDESIKKASQLYLTPEQQRFPQRYIELAIVVDHGMYTKYSSNFKKIRKRVHQMVNNINEMYRPLNIAITLSLLDVWSEKDLITMQAVAPTTARLFGDWRETVLLKQKDHDHAQLLTDINFTGNTIGWAYMGGMCNAKNSVGIVKDHSSNVFMVAVTMTHEIGHNLGMEHDDKDKCKCEACIMSAVISDKPSKLFSDCSKDYYQTFLTNSKPQCIINAPLRTDTVSTPVSGNEFLEAGEECDCGSPSNPCCDAATCKLRPGAQCADGLCCDQCRFKKKRTICRRARGDNPDDRCTGQSADCPRNS", "output": "[Snake venom metalloproteinase HR2a]: Zinc protease that induces hemorrhage.; "}]}
+{"id": "function_test_474", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVKAVCVLAGSGDVKGVVHFEQQDEGAVSVEGKIEGLTDGLHGFHIHVFGDNTNGCMSAGSHFNPENKNHGAPGDTDRHVGDLGNVTAEGGVAQFKITDSLISLKGPNSIIGRTAVVHEKADDLGKGGNDESLKTGNAGGRLACGVIGYSP", "output": "Destroys radicals which are normally produced within the cells and which are toxic to biological systems."}]}
+{"id": "function_test_475", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRTLWIMAVLLVGVEGSLIEFAKMILEETKRLPFPYYTTYGCYCGWGGQGQPKDATDRCCFVHDCCYGKLSNCKPKTDRYSYSRKSGVIICGEGTPCEKQICECDKAAAVCFRENLRTYKKRYMAYPDLLCKKPAEKC", "output": "Snake venom phospholipase A2 (PLA2) that displays local myotoxic activity. It also displays anticoagulant action in plasma and edema-inducing activities . In addition, it shows cytotoxic activity to a variety of cell types and bactericidal activity to a variety of Gram-negative and Gram-positive bacteria . PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides."}]}
+{"id": "function_test_476", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "EDCIPKWKGCVNRHGDCCEGLECWKRRRSFEVCVPKTPKT", "output": "This toxin is a gating modifier that acts principally as an inhibitor on ASIC1a (ASIC isoform 2) and a potentiator on ASIC1b (ASIC isoform 3) . This toxin potently and selectively inhibits rat, mouse and human ASIC1a (IC(50)=0.35-3.7 nM) . The blockade is rapidly reversible . The toxin acts by shifting its steady-state desensitization to more alkaline pH (0.27 pH unit) . At higher concentrations, it potentiates rat and human ASIC1b and activates chicken ASIC1 by stabilizing the open state of these subtypes . The toxin binds most tightly to the open and the desensitized states of ASIC1a (promoting desensitization), whereas it binds most tightly to the open state of ASIC1b (promoting opening) . The toxin also inhibits mouse ASIC1a-ASIC2b (IC(50)=2.64 nM) and rat ASIC1a-ASIC2a . It binds to the extracellular domain at subunit interfaces in the acidic pocket with the majority of contacts on the thumb domain of the channel . It is also noteworthy that calcium competes with the toxin, probably by inhibiting binding of the toxin to the channel ."}]}
+{"id": "function_test_477", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIDQETDGIEKLETGIPGFDFLSDGGLPLGRATLIAGTAGSAKTIFASQFLVEGIQRGENGVFVTFEEPPKALRKNMRGFGWDIQQWENEGKWVFVDASPQPGDRPIVSGEYDLGALIARIEHAVRKYKASRISLDSLGAIFSHLSDSAQVRSDLFRLASALRELGVTAIMTAERVEEYGEISRYGVEEFVADNVVIVRNVLADEKRRRTIEILKYRGTDHQKGEFPFTIINKKGIVIIPLSAIELEQKSSDIRITSGSEELDRMCGSGFFRDSIILVSGATGTGKTLMVTEFMDGGVANGERCLVFAFEESREQLIRNATGWGVDFKQMEKEGKLKVVCRYPETTNLENHLIMMKDIIQEFKPNRVAVDSLSALERVSTLKSFREFIIGLTSFIKQQEIGGLFTSTTPNLLGGASITDAHISTITDSIILLRYVEMYGEMRRGITVLKMRGSMHDKDIREFSIDHQGMHIGKPFRNVTGILAGTPMYTAQSEVERLSGLFDEKI", "output": "Seems to be linked to dark adaption of Synechocystis cells, but is not as essential as the core oscillator KaiAB1C1 for the circadian cycle . KaiB3 and KaiC3 may cross talk with the core oscillator  (Probable). Autophosphorylates and dephosphorylates independently of KaiA . Has a weak ATPase, hydrolyzes 8.5 ATP/monomer/day, has no detectable ATP synthesis activity. ATPase activity reduced 55% by KaiB3 monomer but not the KaiB3 tetramer or KaiA in vitro, reduced 35% by KaiB1 tetramer ."}]}
+{"id": "function_test_478", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSLIERIKNVVWPKDTLSVVWLYTIGSIFWLGVLGIAAMNLRTFLTYDQNSPNVGELYYSALTIHGWAAMIAFVPMAAAAVIGFSLYKSKLSIIHTKQMAIFFWLSNVLLGIAMAGSPDMGWYMYPPLAIESNSQFHAFLFYTTPQLMGMAYLVMSIAVILQTAAFVTLIADAYATKPKGERLNIFAAYGVAFSIVIAVTLPALAAATLWYTLYFFANVPVNNLLWAILFWFYGHPVVYYVPFPLFGALYYYIPQYAGRSLYSEKWARWNIYLLAIGTMGVWVHHLQTWPLPIVLREWVNLSTLILATGSGLTVLNLGLTIFTSRKYDWKDPVGMGALISLIGFILAGAQALVLPENSINPLFHNSYYVVGHFHLMIWTLIIMGYTTVFLDMLRTSFAGFNFSATSSKWMRIGMIWWTAPFMGVGYAMSVAGYLGFLRRMIAYPVIFQPYNLVESFLAEIGIPGLLLTLFVGMFDALAYASKQPVFSSPSVSSFSMQVDKGELVKKIDSEKGVNNVG", "output": "Catalyzes the reduction of oxygen to water.; "}]}
+{"id": "function_test_479", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGSKRIIPSRHRSLSTYEVMFTALFAILMVLCAGLIAVSWLTIKGSEKDAALGKSHEARGTMKITSGVTYNPNLQDKLSVDFKVLAFDIQQMIGEIFQSSNLKNEYKNSRVLQFENGSVIVIFDLLFAQWVSDENIKEELIQGIEANKSSQLVAFHIDVNSIDITESLENYSTTSPSTTSDKLTTSSPPATPGNVSIECLPGSRPCADALKCIAVDLFCDGELNCPDGSDEDSKICATACDGKFLLTESSGSFDAAQYPKLSEASVVCQWIIRVNQGLSIELNFSYFNTYSMDVLNIYEGVGSSKILRASLWLMNPGTIRIFSNQVTVTFLIESDENDYIGFNATYTAFNSTELNNDEKINCNFEDGFCFWIQDLNDDNEWERIQGTTFPPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLEPTLEPVCLSFWYYMYGENVYKLSINISNDQNIEKIIFQKEGNYGENWNYGQVTLNETVEFKVAFNAFKNQFLSDIALDDISLTYGICNVSLYPEPTLVPTSPPELPTDCGGPFELWEPNTTFTSMNFPNNYPNQAFCVWNLNAQKGKNIQLHFEEFDLENIADVVEIRDGEEDDSLLLAVYTGPGPVEDVFSTTNRMTVLFITNDALTKGGFKANFTTGYHLGIPEPCKEDNFQCENGECVLLVNLCDGFSHCKDGSDEAHCVRFLNGTANNSGLVQFRIQSIWHTACAENWTTQTSDDVCQLLGLGTGNSSMPFFSSGGGPFVKLNTAPNGSLILTASEQCFEDSLILLQCNHKSCGKKQVAQEVSPKIVGGNDSREGAWPWVVALYYNGQLLCGASLVSRDWLVSAAHCVYGRNLEPSKWKAILGLHMTSNLTSPQIVTRLIDEIVINPHYNRRRKDSDIAMMHLEFKVNYTDYIQPICLPEENQVFPPGRICSIAGWGKVIYQGSPADILQEADVPLLSNEKCQQQMPEYNITENMMCAGYEEGGIDSCQGDSGGPLMCLENNRWLLAGVTSFGYQCALPNRPGVYARVPKFTEWIQSFLH", "output": "Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases."}]}
+{"id": "function_test_480", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MADPGMMSLFGEDGNIFSEGLEGLGECGYPENTVNPMGQQMPMDQGFPSLQSSLHHPPANQNQAKLTHFDHYNQYEQQKMHLMDQPNRMISNAPGNGIASPHSQYHNPPVPQVPHGSGASGQMGVYPSMQNERHGQPFVDSGSMWGPRAVQVPDQIRAPYQQQQQQPQPTQPPQAPSGPPGQGHPQHMQQMGNYMARGDFSMQQHGQPQQQRMNQFSQGQEGLNQGNPFIATSGPGHLSHVPQQNPSMAPSLRHSVQQFHHHPPTALHGESVAHSPRFSPNPPQQGAVRPQTLNFSSRSQTVPSPTINNSGQYSRYPYSNLNQGLVNNTGMNQNLGLTNNTPMNQSVPRYPNAVGFPSNSGQGLMHQQPIHPSGSLNQMNTQTMHPSQPQGTYASPPPMSPMKAMSNPAGTPPPQVRPGSAGIPMEVGSYPNIPHPQPSHQPPGAMGIGQRNMGPRNMQQNRPFMGMSSTPREMGGHMRPNGCPGVGLADPQAIQERLISGQQLPSQQQSFQQQMPTCPPMQPHPGIHHQSSPPPHPHHQPWAQLHQSPQNTPQKVPVLQHSPSEPFLEKPVPDMTQVSGPNTQLVKSDDYLPSVEPQPQQKKKKKKNNHIAAEGPSKSFGKEDFPGGLDSQNLSRNSVDCSQEDKKKKKKPKAKKEPKDPKEPKEKKEPKTPKVPKTPKEPKEKKAKNTTPKPKTSKKTSNKKTDSESSAAKKKVNKGKEGSENSDLDKTPPPSPHPEDEDDPGVQKRRSSRQVKRKRYTEDLEFKISDEEADDADAAGRDSPSNTSQSEQQESADAEGPVVEKIMSSRSVKKKMENGEEVEIEEFYVKYKNFSYLHCQWASVEELDKDKRIQQKIKRFKAKQGQNKFLSEIDDELFNPDYVEIDRILDFSRSTDDNGEPVTHYLVKWCSLPYEDSTWELKQDIDQAKIEEFEKLMSREPEMERVERPPADDWKKSESSREYKNNNKLREYQLEGVNWLLFNWYNTRNCILADEMGLGKTIQSITFLYEIYLKGIHGPFLVIAPLSTIPNWEREFRTWTELNVVVYHGSQASRRTIQLYEMYFKDPQGRVIKGSYKFHAIITTFEMILTDCPELRNIPWRCVVIDEAHRLKNRNCKLLEGLKMMDLEHKVLLTGTPLQNTVEELFSLLHFLEPGRFPSETTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKNLAPKEETIIEVELTNIQKKYYRAILEKNFAFLSKGGGQANVPNLLNTMMELRKCCNHPYLINGAEEKILEEFKETHNADSPDFQLQAMIQAAGKLVLIDKLLPKLKAGGHRVLIFSQMVRCLDILEDYLIQRRYPYERIDGRVRGNLRQAAIDRFSRPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRENATNGVQQLSKKEIEDLLRKGAYGALMDEEDEGSKFCEEDIDQILLRRTHTITIESEGKGSTFAKASFVASGNRTDISLDDPNFWQKWAKKAELDIDALNGRNNLVIDTPRVRKQTRLYSAVKEDELMEFSDLESDSEEKPSTKPRRPQDKSQGYARSECFRVEKNLLVYGWGRWTDILSHGRYKRQLTEQDVETICRTILVYCLNHYKGDENIKSFIWDLITPTADGQTRALVNHSGLSAPVPRGRKGKKVKAQSSQPMLQDADWLTTCNPDVLFQEDSYRKHLKHHCNKVLLRVRMLYYLRQEVIGDQADRILEGADSSEVDVWIPEPFHAEVPADWWDKEADKSLLIGVFKHGYEKYNSMRADSTLCFLERVGMPDAKAIAAEQRGTDMLADGGDGGEFDREDEDPEYKPTRTPFKDEIDEFANSPPEDKEESIEIHPNKHSESNSELGQLYWPNTSTLTTRLRRLITAYQRSYKRQQMRQEALMKTDRRRRRPREEVRALEAEREAIITEKRQKWTRREEADFYRVVSTFGIIFDPIKHQFDWNQFRAFARLDKKSDESLEKYFNGFVNMCRRVCRMPVKPDDEPPDLSTMIEPITEERASRTLYRIELLRKIREQVLHHPQLGERLKLCQPSLDLPEWWECGKHDKDLLIGAAKHGVSRTDYHILNDPELSFLEAHKNFAQNRGTGNANTVSSLHPVGAGCSQTPPIVPSTPVQEEKSTEQTESKVEGSENPAAKEKSDIKEETDIADKDTKQDCDAEAETGSVKCELKDIEMSTDVDPKSISEKGSEEDEEEKLDDDDKSEESSQPEAGAVSQGKNFDEESNASMSTARDETRDGFYMEDGDPSVVQLLHERTFAFSFWPKDRVMINRLDNICEAVLKGKWPVNRRQMFDFQGLIPGYTPTAVDSPLQKRSFAELSMIGQASISGSEDITASPQLSKEDALNLSVPRQRRRRRRKIEIEAERAAKRRNLMEMVAQLRESQVVSENGQEKVVDLSKASREATSSTSNFSSVTSKFILPNVSTPVSDAFKTQMELLQAGLSRTPTRHLL", "output": "Probable transcription regulator. Maybe involved in the in 45S precursor rRNA production (By similarity)."}]}
+{"id": "function_test_481", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MFGVEPISFCEDMTMIRPRIIVIGVGGAGGNAVNNMILSKIEGVEFIAANTDAQALGLSLADRRIPLGGYVTKGLGAGSRPELGRSAAQESIDDILTAIDDANMVFITAGMGGGTGSGAAPVIAQAARERGILTIGVVTKPFHFEGGHRMGTAEAAIEELQHVVDTLIIIPNQNLFRIASERTTFIDAFKMADNVLNSGVRSVTDLVVKPGLINLDFADIRIVMSEMGKAIMGTGEAEGEPRAVKAAEAAISNPLLGDTSIAGAKGVLINITGGMDMTLFEVDEAANRIRTEVAPDANIIFGSTFDEKLDGKMRVSVVATGIA", "output": "Required for synthesis of single-domain magnetite particles and magnetosomes, especially in the absence of nitrate. Forms filaments, which form bundles in the presence of GTP. Has both GTPase and ATPase activity; GTPase is 2.5 time more efficient. Has no activity on CTP or TTP . May be involved in redox control for magnetite crystallization (Probable). Mild overexpression causes cell elongation . May recruit other proteins (MamX, MamY and MamZ and possibly Mms6) to a complex required for biomineralization (Probable)."}]}
+{"id": "function_test_482", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MALSQATPFSATELLLASATFCLVFWVVKAWQPRVPKGLKSPPGPWSWPLIGHVLTLGKSPHLALSRLSQRYGDVLQIRIGCTPVLVLSGLDTIRQALVRQGDDFKGRPDLYSFTLVADGQSMTFNPDSGPVWAAQRRLAQNALNSFSVASDPASSSSCYLEMHVSKEAEALIGKFQELMAGSGRFDPYDHVVVSVAKVIGAMCFGQHFPQSSGEMVSLVRNTHDFVETASSGSPVDFFPILKYLPNPALQKYKSFNRRFLQFLWKMVQEHHQDFDKNRVQDIVGALFKHYEDNSRASGGLMPQKKTVNLVNDIFAAGFDPITTAISWSLLYLVTNPEIQRKIQQELDTVIGRARRPRLSDRSQLPYLEAFILETFRHSSFVPFTIPHSTIRDTTLNGFYIPKELCVFINQWQVNHDPKLWGDPSEFRPERFLTSHDTTISKTLSEKVMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSVPPGVKVDLTPTYGLTMKPAPCEHVQARLRFPIK", "output": "A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E2. Metabolizes cholesterol toward 25-hydroxycholesterol, a physiological regulator of cellular cholesterol homeostasis. May act as a major enzyme for all-trans retinoic acid biosynthesis in the liver. Catalyzes two successive oxidative transformation of all-trans retinol to all-trans retinal and then to the active form all-trans retinoic acid. Primarily catalyzes stereoselective epoxidation of the last double bond of polyunsaturated fatty acids (PUFA), displaying a strong preference for the (R,S) stereoisomer. Catalyzes bisallylic hydroxylation and omega-1 hydroxylation of PUFA. May also participate in eicosanoids metabolism by converting hydroperoxide species into oxo metabolites (lipoxygenase-like reaction, NADPH-independent). Plays a role in the oxidative metabolism of xenobiotics. Catalyzes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin. Metabolizes caffeine via N3-demethylation."}]}
+{"id": "function_test_483", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQFSEDMIPTVGFNMRKVTKGNVTIKIWDIGGQPRYRSMWERYCRGVNAIVYMIDAADREKIEASRNELHNLLDKPQLQGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCYSISCKEKDNIDITLQWLIQYSKSRRS", "output": "Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins playing a key role in the regulation of lysosomal positioning which is important for nutrient sensing, natural killer cell-mediated cytotoxicity and antigen presentation. Along with its effectors, orchestrates lysosomal transport and fusion. Localizes specifically to lysosomal membranes and mediates anterograde lysosomal motility by recruiting PLEKHM2, which in turn recruits the motor protein kinesin-1 on lysosomes. Required for lysosomal and cytolytic granule exocytosis. Critical factor involved in NK cell-mediated cytotoxicity. Drives the polarization of cytolytic granules and microtubule-organizing centers (MTOCs) toward the immune synapse between effector NK lymphocytes and target cells (By similarity). In neurons, mediates the anterograde axonal long-range transport of presynaptic lysosome-related vesicles required for presynaptic biogenesis and synaptic function (By similarity). Also acts as a regulator of endosome to lysosome trafficking pathways of special significance for host defense. Regulates cargo trafficking to lysosomes by binding to PLEKHM1 and recruiting the HOPS subunit VPS41, resulting in functional assembly of the HOPS complex on lysosomal membranes. Plays an important role in cargo delivery to lysosomes for antigen presentation and microbial killing. Directs the intersection of CD1d with lipid antigens in lysosomes, and plays a role in intersecting phagosomes with lysosomes to generate phagolysosomes that kill microbes (By similarity). Involved in the process of MHC II presentation. Regulates the delivery of antigens to lysosomes and the formation of MHC II-peptide complexes through the recruitment of the HOPS complex to lysosomes allowing the fusion of late endosomes to lysosomes (By similarity). May play a role in chromosome segregation (By similarity)."}]}
+{"id": "function_test_484", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKIKLLCISLAVLFCSSANAQKKQAKVQPSVFPQTVARPKLVVGMVIDQMRWDYLYRFYARYGNGGFKRLINEGFSAENTLIPYTPTLTACGHSSIYTGSVPAINGIIGNNWFDPQLGRDVYCVEDKSVKTVGSSSNEGLMSPKNLLVTTVTDELRMATNFRSKVISVSIKDRGAILPGGHTANGAYWYDDMTGSFISSTHYMQQLPTWVNDFNAQRLPNKYFEQDWNTLYPIETYTESTADAKPYERTFKGAKTSSFPHLFKQYANKNYSMMASMPQGNSFTLEFAKAAIPAEKLGQTGNTDFLAVSLSSTDYVGHQFGPNSIELEDTYLRLDKDLEDFFNYLDKTIGKGNYLLFLTADHGATHVPGFLRNKMPGGRLLLKVQTDLDSLIFNEFKVRCNFTIINNQVIFDTDAIKEAKADYAKIKQSTIDYLVKQDGVLNAVDIKNMGAVTIPQEIKNKIINGYNARRSGDVYIILDAGWYPTLTPGTGHAAWNPYDSHIPALFMGWGVKPGKTNKEYYMSDIAPTVSALLHIQQPSGSIGKVITDLLK", "output": "Alkaline phosphatase with broad substrate specificity."}]}
+{"id": "function_test_485", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAVFVVLLALVAGVLGNEFSILKSPGSVVFRNGNWPIPGERIPDVAALSMGFSVKEDLSWPGLAVGNLFHRPRATVMVMVKGVNKLALPPGSVISYPLENAVPFSLDSVANSIHSLFSEETPVVLQLAPSEERVYMVGKANSVFEDLSVTLRQLRNRLFQENSVLSSLPLNSLSRNNEVDLLFLSELQVLHDISSLLSRHKHLAKDHSPDLYSLELAGLDEIGKRYGEDSEQFRDASKILVDALQKFADDMYSLYGGNAVVELVTVKSFDTSLIRKTRTILEAKQAKNPASPYNLAYKYNFEYSVVFNMVLWIMIALALAVIITSYNIWNMDPGYDSIIYRMTNQKIRMD", "output": "Multifunctional protein which functions as a renin, prorenin cellular receptor and is involved in the assembly of the lysosomal proton-transporting V-type ATPase (V-ATPase) and the acidification of the endo-lysosomal system. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, may also play a role in the renin-angiotensin system (RAS) (By similarity). Through its function in V-type ATPase (v-ATPase) assembly and acidification of the lysosome it regulates protein degradation and may control different signaling pathways important for proper brain development, synapse morphology and synaptic transmission (By similarity)."}]}
+{"id": "function_test_486", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAIPSFLPVLGTKSHRADYKPLQTLSHMLLWITVLFLAPVAGTSADPPKAVVRLEPPWIQVLRGDRVTLTCEGAPSPGNHSTQWLHNGRLIPTQVLPSYRFTAKGNDSGEYRCQAGGTSLSDPVRLDVISDWLVLQTSQLIFQEGDVIVLRCHSWNNWPLAKVTFYHNGVAKKYFSISKNFSIPQANHSHSGAYNCTGLIGRTSHTSPPVTITVQGPKSSDSSMVVIIVAAVIGIATAAIVVAVVAIICLKKKQPPGNPEHREMGETLPEDPGEYSVVFGGSMMSCPGLPDGLEPARTDLSNLSDPEEVAKSEVENTITYSLLKHPEAQDDDTEHDYQNHI", "output": "Binds to the Fc region of immunoglobulins gamma. Low affinity receptor."}]}
+{"id": "function_test_487", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPKTRRQRTRRARRNRPPTPWPISQDLDRASYMDTPSTCLAIVYRPIGVPSQVVYVPPAYIDMPSWPPVQSTNSPGTPSMDALSALLSNTLSLASPPSPPREPQGPSRSLPLPPLLSPPRFHLPSFNQCESTPPTEMDAWNQPSGISSPPSPSPNLASVPKTSTPPGEKP", "output": "Rex escorts unspliced gag-pro-pol and singly spliced env mRNAs out of the nucleus of infected cells. These mRNAs carry a recognition sequence called Rex responsive element (RxRE or XRE) located at the 3' region of the long terminal repeat (LTR). This function is essential since most HTLV proteins are translated from unspliced or partially spliced pre-mRNAs that cannot exit the nucleus by the pathway used by fully processed cellular mRNAs (By similarity)."}]}
+{"id": "function_test_488", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEPVSAECHLPPEDDLLEMMMEQSFTEPEEKSQDKPTRKIIPKTKLCKGVNNRYCVLHIKEVYAQREEKHLTITASQEGDDLELCILKDDWVALQIKPGDIIHLEGNCSVDNTWTISRDTGYLILYPDLLISGTSIANGIRCLRRSVLSEKFKVCDKGSRQMLNGTMLHDIFQRATTCGFTDSVLQELAHHTVHGPKYLKEMYQLKLNQADVMGEIQEYLPSLSKWATDFMTHPLNQQQINRTKSTAGDPTETTKVSEFLDIEENIWSPRFGLKGKIDVTARVKIHQKSKAHLKIMPLELKTGKESNSIEHRSQVVLYTLLSQERREDPEAGLLLYLKTGNMYTVPGNRLDRRELLKIRNELSYYLTNVLHKSDNGSKETTLASLPAMIADRQACKYCSQMRNCALYNRSVEQQTENCYIPPEMIPVVQKETEHLTEDHLQYFRLWYLMCTLEANSKDSKMGRKNIWMMSSSEREEDGQCIGNLIRTGHVQTISDVQYLHSFQRRSGSVPATNLASGDRVVVSGEERFLALSTGYIKEVKDENITCILDRSLVKLPEDLLFRLDHEEGGGGLEFHLGNLSRLMENSSVSEKLRKLIIDFSKPNFVQHLSSILPPDAKDIVASILRGLNKPQKQAMKRVLLSKDYTLIVGMPGTGKTTTICTLVRILYACGFSVLLTSYTHSAVDNILLKLKKFQVGFLRLGRTQKLHPDVQEFSEEEICKAKSIKSLSALEELYNSQPVVATTCMGVNHPIFTRRRFDFCIVDEASQISQPICLGPLFFADRFVLVGDHQQLPPLVKSAEARELGMSESLFKRLERNQEAVVQLTVQYRMNSKIMALSNKLVYEGRLECASDRVSNAVVQLPHIKTLLLELEFRESQESMWIKDVLEPSNPVCFLNTEKIPALETEEKGGISNWIEAKLVFHLTKLYLKAGCRPSDIGIIAPYRQQLKMISNYFNSLSASAVEVNTVDKYQGRDKSVIIVSFVRSNIDGKLGDLLKDWRRLNVALTRAKHKLIMLGCVPTLNRFDCLEQLICNLKTENQIYDLPEGAHEHFPV", "output": "Key enzyme involved in DNA replication and DNA repair in nucleus and mitochondrion. Involved in Okazaki fragments processing by cleaving long flaps that escape fen1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit dna2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA, while the 3'-ssDNA cleavage is prevented by the presence of RPA. Also involved in DNA replication checkpoint independently of Okazaki fragments processing (By similarity). Possesses different enzymatic activities, such as single-stranded DNA (ssDNA)-dependent ATPase, 5'-3' helicase and endonuclease activities. While the ATPase and endonuclease activities are well-defined and play a key role in Okazaki fragments processing and DSB repair, the 5'-3' DNA helicase activity is subject to debate. According to various reports, the helicase activity is weak and its function remains largely unclear. Helicase activity may promote the motion of dna2 on the flap, helping the nuclease function."}]}
+{"id": "function_test_489", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "EDQQNLSQRYIELVVVADHRVFMKYNSDLNIIRKRVHELVNTINGFYRSLNIDVSLTDLEIWSDQDFITVDSSAKNTLNSFGEWREADLLRRKSHDHAQLLTAINFEGKIIGRAYTSSMCNPRKSVGIXKDHSPINLLVGVTMAHELGHNLGMNHDGEKCLRGASLCIMRPGLTPGRSYEFSDDSMGYYQSFLKQYNPQIXNK", "output": "Snake venom zinc metalloprotease that has Aalpha, Bbeta fibrin(ogen)olytic activities. It cleaves the Aalpha chain of fibrinogen first followed by the Bbeta chain and shows no effect on the gamma chain. Does not induce or inhibit platelet aggregation, and is unable to activate plasminogen. Exhibits low lethality when tested on mice. Intravenous administration results in thrombolysis within one hour followed by recanalization. Fibrinogenolytic activity results in a 60% decrease in the rat's plasma fibrinogen level. Histological examination of kidney, liver, heart and lung tissue shows no necrosis nor hemorrhage."}]}
+{"id": "function_test_490", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSPTTDRIAVVGGSISGLTAALMLRDAGVDVDVYERSPQPLSGFGTGIVVQPELVHYLLEQGVELDSISVPSSSMEYVDALTGERVGSVPADWRFTSYDSIYGGLYELFGPERYHTSKCLVGLSQDSETVQMRFSDGTKAEANWVIGADGGASVVRKRLLGIEPTYAGYVTWRGVLQPGEVADDVWNYFNDKFTYGLLDDGHLIAYPIPGRENAESPRLNFQWYWNVAEGPDLDELMTDVRGIRLPTSVHNNSLNPHNLRQFHSKGESLFKPFRDLVLNASSPFVTVVADATVDRMVHGRVLLIGDAAVTPRPHAAAGGAKACDDARTLAEVFTKNHDLRGSLQSWETRQLQQGHAYLNKVKKMASRLQHGGSFEPGNPAFAFGLPKVDEPSVVTNS", "output": "Catalyzes the conversion of 2,6-dihydroxypyridine into 2,3,6-trihydroxypyridine in the nicotine degradation pathway."}]}
+{"id": "function_test_491", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDPLGPAKTQWSWRCCLTALLFQLLVAVCFFSYLRVSRDDPTVYPNGSPFPDSTGTPAHSIPLILLWTWPFNKPIALPRCSEMVPGTADCNITADRKVYPQADAVIVHHREVMYNPSAQLPRSPRRQGQRWIWFNLESPSHCWHLKAMDGYFNLTMSYRSDSDIFTPYGWLEPWSGQPAHPPLNLSAKTELVAWAVSNWRPNSARVRYYQSLQAHLKVDVYGRSHKPLPQGTMMETLSRYKFYLAFENSVHPDYITEKLWRNALEAWAVPVVLGPSRSNYERFLPPDAFIHVDDFQSPKDLAQYLQELDKDHARYLSYFRWRETLQPRSCSWALDFCKACWKLQEESRYQTRSIAAWFT", "output": "Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the N-acetyl glucosamine (GlcNAc) of a distal alpha2,3 sialylated lactosamine unit of a glycoprotein- or glycolipid-linked sialopolylactosamines chain or of a distal or internal lactosamine unit of a neutral glycoprotein- or glycolipid-linked polylactosamines chain through an alpha-1,3 glycosidic linkage and participates in surface expression of the sialyl Lewis X (sLe(x)), Lewis X (Le(x)) and non sialylated VIM2 determinants. Moreover transfers fucose to H-type 2 (Fucalpha1-2Galbeta1-4GlcNAc) chain acceptor substrates and participates in difucosylated sialyl Lewis x determinants. Also fucosylates a polylactosamine substrate having a 6 sulfate modification at the GlcNAc moiety and gives rise to sialyl and non-sialyl 6-sulfo lewis X. Does not have activity towards type 1 ((Galbeta1-3GlcNAc)) and H-type 1 chain (Fucalpha1-2Galbeta1-3GlcNAc) acceptors substrates."}]}
+{"id": "function_test_492", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGRKHYSSKKNRSKKGEFVNWDLIERKNENFEKYYRLQKLVTEDDFILLKQKLTEQLPTTFRITASIPHATQVRDYFIEHYYPLIENARTEDAKIPLPVSLPWYPDGMAFMLDISKEVIRKSPHLKALQEFLVLETEAGDINRQESVSMVPPLLLNVESHHKVLDMCAAPGSKTAQLLEALHKPTKKEDITTLLPSGIVIANDSDNKRAHMLVHQIKRLNSPNVLIVNHDASFLPNFHLSSPDGKKFLKFDRILADVPCSGDGTFRKNIALWNEWSLKTALGLHATQIKILMRGLQLLEKGGRLVYSTCSLNPIENEAVVSAVLNATRGSVRLVDVSSELPQLKRSQGVDNWVVCDSDLNIYPSFDTLPKELYEKMPPTLWPLPKKELAELNIQNCLRIYPHFQNTGGFFVAVLEKYENLTSSMKTAVDDNKVFLREQKLPSEQASKKRKQDTQETSSDSKLAEVKPKGKNGGNRFHELDPFVYIKEDDQALEKIYKKFGIDEAIIKKNQFFVRNVNGVPTKAIYISNDLFRNVIENNRNRVKFVHGGLKIFVRQDFGSLSREIAEKNGTCVFRVQSDGANLASHFIAESCLFHTTLSDLFILLDHEAVTIDDFPEDSLFRKEYNHLDLGSTLLHVDLAKEESVIKKQVYIPLWKSVRICNVLLSNSEKRTLKLQIEGPQSSIHKHNT", "output": "tRNA cytosine C(5)-methyltransferase that methylates cytosine to 5-methylcytosine (m5C) in tRNAs at position 34 and 48 . Trm4a and trm4b methylate different sets of tRNAs . Also methylates cytosine to m5C at positions (60, 61 and 62) in tRNA(Asp) ."}]}
+{"id": "function_test_493", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGARASVLSGGKLDAWEKIRLRPGGKKKYKLKHLVWASRELERFALNPGLLETTEGCRQIITQIQPSIQTGSEEIKSLYNTIAVLYFVHQKIEVKDTKEALDKLEEEQNKSQRKTQQEAADKGVSQNYPIVQNLQGQMVHQALSPRTLNAWVKVIEEKAFSPEVIPMFTALSEGATPQDLNTMLNTVGGHQAAMQMLKDTINDEAAEWDRLHPVHAGPIPPGQMREPRGSDIAGTTSTLQEQIAWMTSNPPVPVGEIYKRWIILGLNKIVRMYSPVSILDIRQGPKEPFRDYVDRFFKTLRAEQATQEVKNWMTDTLLVQNANPDCKTILKALGPGASLEEMMTACQGVGGPSHKARILAEAMSQVTNPVVMMQKGNFKGHRKIVKCFNCGKEGHIARNCRAPRKKGCWKCGKEGHQMKDCTERQANFLGKIWPSHKGRPGNFLQSRPEPTAPPAESFGFGEEITPSPRQETKDKEQSPPLTSLKSLFGNDPLSQ", "output": "[Gag polyprotein]: Mediates, with Gag-Pol polyprotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical particles, recruiting the viral Env proteins, and packaging the genomic RNA via direct interactions with the RNA packaging sequence (Psi).; "}]}
+{"id": "function_test_494", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MFFINFKKIKKKQFPIYLTQHRIITVFLIFIYFINLKDCFHINNSRILSDVDKHRGLYYNIPKCNVCHKCSICTHENGEAQNVIPMVAIPSKRKHIQDINKEREENKYPLHIFEEKDIYNNKDNVVKKEDIYKLRKKKKQKKNCLNFLEKDTMFLSPSHDKETFHINHMNKIKDEKYKQEYEEEKEIYDNTNTSQEKNETNNEQNLNINLINNDKVTLPLQQLEDSQYVGYIQIGTPPQTIRPIFDTGSTNIWIVSTKCKDETCLKVHRYNHKLSSSFKYYEPHTNLDIMFGTGIIQGVIGVETFKIGPFEIKNQSFGLVKREKASDNKSNVFERINFEGIVGLAFPEMLSTGKSTLYENLMSSYKLQHNEFSIYIGKDSKYSALIFGGVDKNFFEGDIYMFPVVKEYYWEIHFDGLYIDHQKFCCGVNSIVYDLKKKDQENNKLFFTRKYFRKNKFKTHLRKYLLKKIKHQKKQKHSNHKKKKLNKKKNYLIFDSGTSFNSVPKDEIEYFFRVVPSKKCDDSNIDQVVSSYPNLTYVINKMPFTLTPSQYLVRKNDMCKPAFMEIEVSSEYGHAYILGNATFMRYYYTVYRRGNNNNSSYVGIAKAVHTEENEKYLSSLHNKINNL", "output": "During the asexual blood stage, initiates the proteolytic maturation of several rhoptry proteins and thus, is required for merozoite invasion of host erythrocytes and probably the subsequent development of the ring-stage . Cleaves rhoptry associated protein 1 RAP1 and apical sushi protein ASP during schizont maturation . Also cleaves rhoptry protein RON3 (By similarity)."}]}
+{"id": "function_test_495", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSPMKQNESESHSVSEPIAIIGSAYRFPGGCNTPSKLWDLLRQPRDILKEIDPERLNLRRYYHPDGETHGSTDVANKAYTLEEDISRFDASFFGISPLEAASMDPQQRTLLEVVYESTETAGIPLDKLRGSLTSVHVGVMTTDWAQMQRRDPETMPQYTATGIASSIISNRISYIFDLKGASETIDTACSSSLVALHNAARALQSGDCEKAIVAGVNLILDPDPFIYESKLHMLSPDARSRMWDAAANGYARGEGAAAVVLKTLGHALRDGDRIEGVIRSTFVNSDGLSSGLTMPSSAAQTALIRQTYRKAGLDPVRDRPQFFECHGTGTKAGDPVEARAISDAFLPPSHRTNGAATTVDAPLYVGSIKTVVGHLEGCAGLAGLVKVLLSLKHGIIPPNLWFDKLNPEIARYYGPLQIPTKAIPWPKLAPGTPLRASVNSFGFGGTNAHAIIERYDASQSYCSQWRRNMTEEKTIARTQNNESIEIPVPLVLTAKTGRALWRTVDAYAQHLRQHPKLRVTNLSQFMHSRRSTHRVRASFSGASREELVENMAKFVQAHAADAKSPASQNRIGYSPLHIDPKEAPGILGVFTGQGAQWPAMGRDMMHQSPLFRKTIADCESVLQALPAKDAPVWSLSEELKKDASTSRLGEAEISQPLCTAVQLALVNVLLASGVHFDAVVGHSSGEIAATYASGIINLEAAMQIAYYRGLYAKLARGETDAAGGMMAAGLSMNDAVKLCRLPEFEGRIHVAASNAPQSVTLSGDKEAIKAAKAKLDADGVFARELKVDTAYHSHHMLPCAEPYLKALLACDIQVSAPTTTPGRKCMWSSSVRGDAELLRHDRNLDSLKGPYWVANMVQTVLFSRAVQSTIWHGGPFDLAVEVGPHPALKGPTEQTLKAVYGSAPLYTGVLSRGANDAVAFSTAIGNIWSHLGPAFVDITGYQSIFSSTCEGHGGGSAAPFISDLPLYPWDHDEEYWRESRISRRHRTGKDESHELLGRRTPDDNEREIRWRNLLKVSELPWTQGHRVLGEVLLPGAAYISMAIEAGRRLALDQGREARLLEVSDVDILRPVVVADNKEGTETLFTVRLLDEYASTGKKSDELITASFSFYIYNSPASTSIVHTCEGRIAVQLGAKLGSEAGANSMPQLPHREPSISNLQQLDCEKLYSVFETIGLEYSGAFRRIVSSSRCLGHATATASWPTTDLNDCYLIHPAILDVAFQTIFVARAHPDSGQLSSALLPSRIERVRVVPSLAMGSKLQNNENFNAAIDSWALNQTASSLTGNINVYDAESGRALIQVEGFEVRAVGEPDASKDRLLFYETVWGRDISIMGLSDPIRDETSDAMVHNLSEAIERVSLFYVRQLMGELSTADRRQANWYHTRMLAAFDYHLAKVHEETHLHLRPEWLADDWAVIQTIDEAYPDAVELQMLHAVGQNVADVIRGKKHLLEVLRVDNLLDRLYTEDKGMHMANLFLANALEEITFKFPRCKILEIGAGTGATTWAALSAIGEAFDTYTYTDLSVGFFENAVERFSAFRHRMVFRALDIEKDPASQSFDLNSYDIIIATNVLHATRNLGVTLGNVRALLKPGGYLLLNEKTGPESLRATFNFGGLEGWWLAEEKERQLSPLMSPDGWDAQLQKASFSGVDHIVHDVQEDQQDKQQNSMIMSQAVDDTFYARLSPLSEMANLLPMNEPLLIIGGQTTATLKMIKEIQKLLPRQWRHKVRLIASVDHVEAEGLPAHSDVICLQELDRGLFTTAMTSKCLDALKTLFINTRNLLWVTNAQNSSSMTPRASMFRGITRVLDGEVPHIRTQVLGIEPRETPSATARTLLEAFLRLRSDDGRHAGNVDEDGADGSSQQVLWLHEPEAELLSNGTMMVPRVKARKSLNDTYLASTRAISTTVDARCVSVQAVAGPAKMLLRPVEDFAGEHAISNQTSDSKVHIQVESTLHIPEALDGTCLYLVCGWTRTAETSVPVIALSANNASMVAVESKAVAMIDEVDVKPETLLRVFQHMAMQALDSAVKRHGQGQSTALIYGADEELAKLTSERFAVRESKVYFASSRTFAPGDWLKVQPLLSKFALSQMIPADVEVFIDCLGDTESFDACRTLQSCLSTTRTVQHRLDACLLSQMSRCSPDALVDAYSYAKTQSNAEFSWNGYVKTFTAAELAGKLSHSLIHSVYMTNWQKKDSILVTVPPLQTRGLFKSDRTYLMVGAAGGLGTSICRWMVRNGARHVVVTSRNPKADPEMLNEAERYGAAVQVVPMDACSKDSVQTVVDMIRATMPPIAGVCNAAMVLRDKLFLDMNVDHMKDVLGPKMQGTEHLDSIFAQEPLDFFVLLSSSAAILNNTGQSNYHCANLYMDSLVTNRRSRGLAASIIHVGHVCDTGYVARLVDDTKVQMSLGTTRVMSVSETDVHHAFAEAVRGGQPDSRSGSHNIIMGIEPPTKPLDLTKRKPVWISDPRLGPCLPFSTLENQMMASEQAAAASAVDSLAQQVSEATTD", "output": "Hybrid PKS-NRPS synthetase; part of the gene cluster that mediates the biosynthesis of tenellin-type 2-pyridones, iron-chelating compounds involved in iron stress tolerance, competition with the natural competitor fungus Metarhizium robertsii and insect hosts infection . TenS catalyzes the assembly of the polyketide-amino acid backbone . Because tenS lacks a designated enoylreductase (ER) domain, the required activity is provided the enoyl reductase tenC . Upon formation of the polyketide backbone on the thiotemplate, the triketide is transferred to the NRPS module and linked to tyrosine to produce the pyrrolidine-2-dione intermediates, including pretellinin A, 11-hydropretellenin A, 12-hydropretellenin A, 13-hydropretellenin A, 14-hydropretellenin A, 12-oxopretellenin A and prototellinin D . The pathway begins with the assembly of the polyketide-amino acid backbone by the hybrid PKS-NRPS tenS with the help of the enoyl reductase tenC. These enzymes catalyze the synthesis of the pyrrolidine-2-dione intermediates pretellinin A, 11-hydropretellenin A, 12-hydropretellenin A, 13-hydropretellenin A, 14-hydropretellenin A, 12-oxopretellenin A and prototellinin D. The cytochrome P450 monooxygenase tenA then catalyzes an oxidative ring expansion of pretenellin A and 14-hydropretellenin A to form the 2-pyridone core, leading to pretenellin B and pyridovericin, respectively. The cytochrome P450 monooxygenase tenB is then required for the selective N-hydroxylation of the 2-pyridone nitrogen of yield tellinin and 15-hydroxytellenin (15-HT), respectively. The UDP-glucosyltransferase GT1 and the methyltransferase MT1, located outside the tenS gene cluster, contribute to the stepwise glycosylation and methylation of 15-HT to obtain the glycoside pyridovericin-N-O-(4-O-methyl-beta-D-glucopyranoside) (PMGP). Additional related compounds such as 1-O-methyl-15-HT, (8Z)-1-O-methyl-15-HT, and O-methyltenellin A are also produced but the enzymes involved in their biosynthesis have still to be determined ."}]}
+{"id": "function_test_496", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIYQSPTIQVELLEDNIAKLCFNAPGSVNKFDRETLTSLDAALDSIKQDSNIKALVLTSSKDTFIVGADITEFLGLFAQDDAVLLSWVEQANAVFNKLEDLPFPTASAIKGFALGGGCETILATDFRIADTTAKIGLPETKLGIIPGFGGTVRLPRVIGADNALEWITTGKDQRAEDALKVGAVDAVVAPQALEAAAIQMLKDAVAEKLDWQARRNRKLSALTLPKLEAMMSFTTAKGMVFAVAGKHYPAPMAAVSVIEQASTKGRAEALQIEHQAFIKLAKTDVAKALIGIFLNDQFVKGKAKKAGKLAKEVNNAAVLGAGIMGGGIAYQSASKGTPIVMKDIAQPALDLGLNEAAKLLSAQVARGRSTPEKMAKVLNNITPSLDYAAIKHSDVVVEAVVEHPKIKAQVLAEVEGYVSEDAIIASNTSTISINLLAKSMKKPERFCGMHFFNPVHKMPLVEIIRGEHSSEETIASVVAYASKMGKTPIVVNDCPGFFVNRVLFPYFAGFNGLLAEGGDFAAIDKVMEKQFGWPMGPAYLLDVVGLDTGHHAQAVMAEGFPDRMGKSGTDAIDVMFENKRLGQKNGKGFYVYSVDSRGKPKKDVDPTSYGLLKDAFGELKAFEADDIIARTMIPMIIETVRCLEEGIVASPAEADMGLVYGLGFPPFRGGVFRYLDTMGVANFVALADKYAHLGGLYQVTDAMRTLAANNGSYYQA", "output": "Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate."}]}
+{"id": "function_test_497", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MVAVAILAAGKGTRMKSSLPKVLHPLGSRSLVERVLNVSESLHPQRKLVIIGYQGQQVRNTLQHLDDIEFVEQKEQLGTGHAIQQLIPHLEDFQGDLLVLNGDVPLLRPETLQNLLQIHQDHGNAATLLTANLPNPKGYGRVFCDGNNLVKQIVEERDCTDAQRQNHRINGGIYCFNWSKLAAILPNLTPNNDQGEYYLTDVVNFLDPVMAVDVEDFLEITGINDRKQLAAAYDILQTRVKDDWMAAGVTIIDPDSVTIEDTVTLSADVIIEPQTHLRGETIIASGCRIGPGSLIENSRIGSDVTVLFSVISDSQVDSGCRIGPYAHLRGEAKIGANCRVGNFVEIKKSSIGNKTNIAHLSYLGDATLGEKVNVGAGTITANYDGVKKHQTMIGSGTKTGANSVLVAPLKLGKNVTVAAGSTITKNVPDNALVIARESQRVIENWADQFQ", "output": "Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain."}]}
+{"id": "function_test_498", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVNLWEDMETGPNAPDEIYAVVECLKGERNKYEYDKDIPGVVLDRVLHSNVHYPSDYGFIPQTYYDDEDPFDVLVLVEDQTFPGCVIEARPVALMKMDDDGEQDDKVIAVPVEDPRYDHIEDLDDIPQQTLDEIDEFFATYKNLEAGKEVETLGWEDKQAAKDAIEHAMDLYEENFA", "output": "Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions (By similarity) . The hydrolysis of PPi by inorganic pyrophosphatase releases a considerable amount of energy that can drive unfavorable biochemical transformations to completion (Probable). Is not active on nucleoside triphosphates (ATP, TTP, GTP, or CTP) or nucleoside diphosphate (ADP) ."}]}
+{"id": "function_test_499", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIQKLSNLLVTALAVATGVVGHGHINDIVINGVWYQAYDPTTFPYESNPPIVVGWTAADLDNGFVSPDAYQNPDIICHKNATNAKGHASVKAGDTILFQWVPVPWPHPGPIVDYLANCNGDCETVDKTTLEFFKIDGVGLLSGGDPGTWASDVLISNNNTWVVKIPDNLAPGNYVLRHEIIALHSAGQANGAQNYPQCFNIAVSGSGSLQPSGVLGTDLYHATDPGVLINIYTSPLNYIIPGPTVVSGLPTSVAQGSSAATATASATVPGGGSGPTSRTTTTARTTQASSRPSSTPPATTSAPAGGPTQTLYGQCGGSGYSGPTRCAPPATCSTLNPYYAQCLN", "output": "Has endoglucanase activity on substrates containing beta-1,4 glycosidic bonds, like in carboxymethylcellulose (CMC), hydroxyethylcellulose (HEC) and beta-glucan. May be involved in the degradation of complex natural cellulosic substrates."}]}
+{"id": "function_test_500", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDAPRRSSRLAAKIANVLDSKGTIIPEAAPVMLKKPAKDESVDSTIQVGDVIPDITLPDEDGTSIRLRDITANKGLVIFAYPKASTPGCTKQGCGFRDNYPKIQASDYEVLGLSFDTSKAQKAFKDKQNFPYHLLSDPKGELIKKLGAEKPGGGKLFRSHWIFEKGTGKCIVKEIDISPLVSVDKAFAVITDSEP", "output": "Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events (By similarity). Acts as a scavenger of H(2)O(2) ."}]}
+{"id": "function_test_501", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MALSVNDCARLTGQSVPTMEHFLPLRNIWNRVRDFPRASTTAAGITWMSRYIYGYHRLMLEDLAPGAPATLRWPLYRQPPPHFLVGYQYLVRTCNDYVFDSRAYSRLRYTELSQPGHQTVNWSVMANCTYTINTGAYHRFVDMDDFQSTLTQVQQAILAERVVADLALLQPMRGFGVTRMGGRGRHLRPNSAAAAAIDARDAGQEEGEEEVPVERLMQDYYKDLRRCQNEAWGMADRLRIQQAGPKDMVLLSTIRRLKTAYFNYIISSTSARNNPDRRPLPPATVLSLPCDCDWLDAFLERFSDPVDADSLRSLGGGVPTQQLLRCIVSAVSLPHGSPPPTHNRDMTGGVFQLRPRENGRAVTETMRRRRGEMIERFVDRLPVRRRRRRVPPPPPPPEEEEGEALMEEEIEEEEEAPVAFEREVRDTVAELIRLLEEELTVSARNSQFFNFAVDFYEAMERLEALGDINESTLRRWVMYFFVAEHTATTLNYLFQRLRNYAVFARHVELNLAQVVMRARDAEGGVVYSRVWNEGGLNAFSQLMARISNDLAATVERAGRGDLQEEEIEQFMAEIAYQDNSGDVQEILRQAAVNDTEIDSVELSFRLKLTGPVVFTQRRQIQEINRRVVAFASNLRAQHQLLPARGADVPLPPLPAGPEPPLPPGARPRHRF", "output": "Protein covalently bound to the viral DNA that acts as a primer for viral genomic replication by DNA strand displacement. Assembles on the viral origin of replication in an initiation complex with viral polymerase, DBP, host NFIA and host POU2F1/OCT1. During initiation, the polymerase covalently couples the first dCTP with Ser-580 of pTP. The terminal protein stimulates the template activity over 20 fold compared to protein-free templates. Neo-synthesized viral genomes are linked to two preterminal proteins, one for each 5' end. These new genomes are encapsidated in the nucleus, and during capsid maturation by viral protease, preterminal protein is first cleaved into intermediary (iTP), then into mature TP. May play a role in host nuclear matrix localization of genomic DNA."}]}
+{"id": "function_test_502", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKNKKEVYGFRKSKVAKTLCGAVLGTALIAFADKAVFADEVTETTSTSTVEVATTGNPATNLPEAQGEMSQVAKESQAKAGSKESALPVEVSSADLDKAVADAKSAGVKVVQDETKDKGTATTATDNAQKQDEIKSDYAKQAEEIKTTTEAYKKEVAAHQAETDKINAENKAADDKYQKDLKSHQEEVEKINTANATAKAEYEAKLAQYQKDLATVKKANEDSQQDYQNKLSAYQTELARVQKANAEAKEAYEKAVKENTAKNEALKVENEAIKQRNETAKATYEAAMKQYEADLAAIKKANEDNDADYQAKLAAYQTELARVQKANAEAKEAYDKAVKENTAKNTAIQAENEAIKQRNETAKATYDAAVKKYEADLAAVKQANATNEADYQAKLAAYQTELARVQKANADAKATYEKAVEDNKAKNAAIKAENEEIKQRNAVAKTDYEAKLAKYEADLAKYKKEFAAYTAALAEAESKKKQDGYLSEPRSQSLNFKSEPNAIRTIDSSVHQYGQQELDALVKSWGISPTNPDRKKSRAYSYFNAINSNNTYAKLVLEKDKPVDVTYTGLKNSSFNGKKISKVVYTYTLKETGFNDGTKMTMFASSDPTVTAWYNDYFTSTNINVKVKFYDEEGQLMNLTGGLVNFSSLNRGNGSGAIDKDAIESVRNFNGRYIPISGSSIKIHENNSAYADSSNAEKSLGARWNTSEWDTTSSPNNWYGAIVGEITQSEISFNMASSKSGNIWFAFNSNINAIGVPTKPVAPTAPTQPMYETEKPLEPAPVAPSYENEPTPPVKTPDQPEPSKPEEPTYETEKPLEPAPVAPSYENEPTPPVKTPDQPEPSKPEEPNYETEKPLEPAPVAPSYENEPTPPVKIPDQPEPSKPEEPTYDPLPTPPLAPTPKQLPTPPVVPTVHFHYSSLLAQPQINKEIKNEDGVDIDRTLVAKQSIVKFELKTEALTAGRPKTTSFVLVDPLPTGYKFDLDATKAASTGFDTTYDEASHTVTFKATDETLATYNADLTKPVETLHPTVVGRVLNDGATYTNNFTLTVNDAYGIKSNVVRVTTPGKPNDPDNPNNNYIKPTKVNKNKEGLNIDGKEVLAGSTNYYELTWDLDQYKGDKSSKEAIQNGFYYVDDYPEEALDVRPDLVKVADEKGNQVSGVSVQQYDSLEAAPKKVQDLLKKANITVKGAFQLFSADNPEEFYKQYVATGTSLVITDPMTVKSEFGKTGGKYENKAYQIDFGNGYATEVVVNNVPKITPKKDVTVSLDPTSENLDGQTVQLYQTFNYRLIGGLIPQNHSEELEDYSFVDDYDQAGDQYTGNYKTFSSLNLTMKDGSVIKAGTDLTSQTTAETDATNGIVTVRFKEDFLQKISLDSPFQAETYLQMRRIAIGTFENTYVNTVNKVAYASNTVRTTTPIPRTPDKPTPIPTPKPKDPDKPETPKEPKVPSPKVEDPSAPIPVSVGKELTTLPKTGTNDATYMPYLGLAALVGFLGLGLAKRKED", "output": "May bind sialic acid residues of salivary agglutinin (SAG) in a calcium-dependent reaction. The interaction of SAG with its receptor in various oral streptococci modulate bacterial colonization of oral tissue and is associated with reduced levels of dental caries."}]}
+{"id": "function_test_503", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MVAFSSLICALTSIASTLAMPTGLEPESSVNVTERGMYDFVLGAHNDHRRRASINYDQNYQTGGQVSYSPSNTGFSVNWNTQDDFVVGVGWTTGSSAPINFGGSFSVNSGTGLLSVYGWSTNPLVEYYIMEDNHNYPAQGTVKGTVTSDGATYTIWENTRVNEPSIQGTATFNQYISVRNSPRTSGTVTVQNHFNAWASLGLHLGQMNYQVVAVEGWGGSGSASQSVSN", "output": "Glycoside hydrolase involved in the hydrolysis of xylan, a major plant cell wall hemicellulose made up of 1,4-beta-linked D-xylopyranose residues. Catalyzes the endohydrolysis of the main-chain 1,4-beta-glycosidic bonds connecting the xylose subunits yielding various xylooligosaccharides and xylose . The catalysis proceeds by a double-displacement reaction mechanism with a putative covalent glycosyl-enzyme intermediate, with retention of the anomeric configuration ."}]}
+{"id": "function_test_504", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MASGVMVSDDVIKVFNEMKVRHQLSPEDAKKRKKAVVFCLSDDKKTIILEPGKEILQGDIGCNVEDPYKTFVKMLPRNDCRYALYDALYETKETKKEDLVFVFWAPEEASLKSKMIYASSKDAIKKRLPGIKHEWQINTYEDVNDPCNLADKLGGNTVVSLEGKSVRS", "output": "May play a role in the regulation of cell morphology and cytoskeletal organization (By similarity). Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Required for formation of the cleavage furrow during cytokinesis."}]}
+{"id": "function_test_505", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNNLTPENIRQTILATPFLLNRIRTEFPQLAAVLNDPNAFATTWQSINASQLLQIPSSTYSMGMPSFSEDDLFDVEVQRRIEEQIRQNAVTENMQSAIENHPEVFGQVYMLFVNVEINGHKVKAFVDSGAQATILSADCAEKCGLTRLLDTRFQGVAKGVGMAKILGCVHSAPLKIGDLYLPCRFTVIEGRDVDMLLGLDMLRRYQACIDLENNVLRIHGKEIPFLGESEIPKLLANVEPSANAHGLGIEPASKASASSPNPQSGTRLGTKESVAPNNEGSSNPPSLVNPPTDPGLNSKIAQLVSMGFDPLEAAQALDAANGDLDVAASFLL", "output": "Recognizes and binds polyubiquitin chains . Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation. Aspartic protease. Appears to act as negative regulator of constitutive exocytosis. May act at the level of secretory vesicle docking and fusion as a competitive inhibitor of SNARE assembly. Required for S-phase checkpoint control (By similarity)."}]}
+{"id": "function_test_506", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLTGVIEGFYGRDWRRDERATVMDWIAAAGMNTYIYGPKDDVHVRARWRVPYDAAGLARLTELRDAAAARGMVFYVSLAPCLDVTYSDPQDRAALLARVDQLARAGLRNLVLLFDDIPSVLPEADRHRFDSFAEAQADLSNMVLRHLRGAGHVVFCPTEYCGRMAGGDPRGSAYLQRLGSTLDPAIDIFWTGPEIVSEEIVAAHLAAVGEVLRRRPVIWDNFHANDYDIRRVFAGPLGGRSRDILPLVAGWITNPNNEAEANFPAIHTTGAYLADPDYAPERAIAAAVAAWQPRFRLAFGDGAVPSDLVALLCDLFWQPFALGPETTRILSALRAALTVPRPDPSDPAWRAALEDLRDLKRRINKLFTLMTEIENRDLFHTFHNYLWEAQEEVGHLVAYCDWLDEAPPPGAVFPATDRIHNFYRRGFGVAVQDILQRDRQGRYHHGV", "output": "Cleaves GlcNAc from O-glycosylated proteins. Can use p-nitrophenyl-beta-GlcNAc and 4-methylumbelliferone-GlcNAc as substrate (in vitro)."}]}
+{"id": "function_test_507", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSSPDGGYASDDQNQGKCSVPIMMTGLGQCQWAEPMTSLGEGKLKSDAGSANSRSKAEARIRRPMNAFMVWAKDERKRLAQQNPDLHNAELSKMLGKSWKSLTLAEKRPFVEEAERLRVQHMQDHPNYKYRPRRRKQVKRMKRAENGFMHMAEAQESAVLGADGRMCLENFSLGYHEQTYPHGQVPQSSHYREPQAVAPHYDGYSLPTPESSPLDLAEADPVFFTSPAQDECQMMPYSYNGSYPHQQNSMLVRQMPQTEQMGQVSPVQGMMACQSSPHMYYGQMYLPGSARHHQLHQAGQPSPPPEAQQMGRADHIQPADMLAEVDRTEFEQYLSYVAKSDLGMHYHAQESVVPTADNGPISSVLSDASTAVYYCNYPSA", "output": "Transcriptional activator. Binds to the DNA sequence 5'-AACAAT-3' (By similarity). All of the sox17 proteins are required for embryonic endoderm development and gastrulation movements, and show some redundancy in function. In addition, the sox17 proteins have distinct but overlapping roles in later gut development. Acts downstream of vegt-signaling in endoderm differentiation to induce a range of endodermal genes both directly (including endodermin and dhh/chh) and indirectly. Also represses wnt-responsive genes to inhibit wnt/beta-catenin signaling."}]}
+{"id": "function_test_508", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MFNFPHPAIDLASRMKSSPLMAGGSSSASSEDLFSPPMMEDLDTPMTEYPMGSPPRMPYRGEDIEIAFLRSEASIKKSSLFNDKFAATLDDLSARPIDSASLIGKLQSMTRSVREILDSGDQLVHEDGPQEILKQFVRVVNKHLCQDEDIHTVLAPLALEPEEKFHIIQTYYQAISMTQFVSPKWTSSLLSDALCRRANIVTVFNGQGVEGYFSELQHLYDTYGGLLAEPLYALSKQLKGLASDVRAQDMYPHGLDVIGWLENPEARPSTDYLLSAPVSQPLIGLVQLLNYAITCKILNKSPGEFARHLSGSAGHSQGIVVAAMLATVVSWPTFFDAASTALQVLFWIGCRSQQCYPSHSIPPSLVDQSERLSPMLSVKGASRESLLKYLDEHNRHLPPAQQGSLALINGRQQFVVAGNPLSLYAFANKLRAASNNSSTTNTARVPFSQRPLLITARFLPISVPFHTSLLEDAEAQILEDLRSVHVPGNSLLFPVLRTDNGADLREFDNLVPELVHMVVCGVVDWDRATRFPTATHLLDFGPGRETGIGALLASTKAGTAARVILSTTLTGPSKKTLGYMPELLSRRRPVVYNTSWEQDFAPRLVRVGDDILLDTKFSRALGLPPVMVAGMTPTTVSPDFVAEVINANYHIEIAGGGYHDAAGMRSALTRLVNLIPAGRGITVNLIYANPRAMGWQIPLLVQLRQEGLPITGLTIGAGVPSPDIASEYIRDLGLSHISFKPGSKEAIDNVLRIAESNPGFPIILQWTGGRAGGHHSYEDFHEPILDRYAQIRAYPNLILVAGSGFGGSDDTIPYITGSWSKKLGYAAMPFDGVLVGSRVMTAKEARTSPAVKQAIVDTPGVPDSQWEGTYKKATGGIITVKSEMGEPIHKLATRGVLLWAELDKEVFSLPAAQQVQELQRRKGSLMKRLNADFQKVWFGIDQQGNPVEISEMTYAEVLTRAVDLLYLKDQQAWIDPSYRSFVADFIRCVENRLSARQPRPRAVFQSALQLDRPQVFLSEFLQAYPAALEDVIVREDEDQLVKLYKQPGRKPLPFIVALDESFEYWFKKDSLWQSERLEAVTNQDVGRICILHGPVAAQYTKVANEPVKQILDNIHKPHVQAILKQQYAGDTSRVPTLDYLYSAGAVSPMLSPQDELLLPHVKHSRSYDPPTLAYDLEGPEENLPTEKQWLALIGGTKPSWRKALLTLNEIVQGKMLVENPIKGLFAPRAGLSVRIIQAGRPQKTVILMRQKSSQGQEKDEATVEIRALSTSEIMLTLRAPMTGGSAGNPPVDLVLYFTYKPTYGNNPIHEVMGTRNQRISRFYEQLWVGNAGDEGTSLQKSADDVQVLTREAILNFTKAIDNRNSAYNGKKNSKLLAPLDMAIVVAWKPLMRCLFTDAVNGDILKLLHLKNDFRVIDNASPMREGDVLSSTAAIESIRIRPDSGKVVRAVATIFKKGTPIITVASEFILQGRYEDYHNTFETKEEQVYKLPLKSKRDVVLLASKPWFRIAAADLSLDDHLDDELTFRLKSSYHFRDANTYSQIETCGTVSCAVGNKDMTIGTVMFKSNSHFLKNPVIDFLTRRGFAYDEVKQLPNAVPLAADVRIEMPTSSDQYAAASGDSNPIHLSRAFARYAGHNEGRVIHGMQTSGLVRGVVELHAAGNDPRRMKAWSASFKGKVSPGETLLVDISHTGMNNGRLIVVATARSESSSVEVFRATAEVAQKPGAYLFTGQGSQKPAMGMDLYETSQAARDVWHTAEQFFVNTYGISILEIVRNNPKEYTVHFGGSRGKAIRENYISLDFEVVNEQGEIESVRAFQEITPSSRSFTYTSSGGLLHETIFTQPALVVMELARFHDMRARGLINEDSCYAGHSLGEYAALAAMGEVFTVEGVTAAVFYRGLTMQKSIELDRSGRDYSMVAANPSRVSKNLSESDLCAIVDSIEAATGGLCEIVNFNVESTQYVCAGDLRSLDCLAGVLDSLVAHPEHLTSLETLNASVPAIVASCLAQTDKKPTPLVLQRGKATIPLKVNVPFHSSLLRPGADTFRRALRKAIPEHMVRPEKLIGRYIPNLTAMPFELSKGYFENVLAISESPFVREILERWDDNNVAVAVC", "output": "Fatty acid synthase beta subunit; part of the gene cluster that mediates the biosynthesis of aspercryptins, linear lipopeptides built from six amino acids including 2 highly unusual and nonproteogenic amino acids, 2-amino-octanoic acid (2aoa) and 2-amino-dodecanol (2adol) . The core structure of aspercryptins is as follows: Ser/Ala-Thr-Ile/Val-2aoa-Asn-2adol . The first step of aspercryptin biosynthesis is the generation of the fatty acid precursors, octanoic and dodecanoic acids, by the FAS subunits atnF and atnM . The fatty acid precursors are likely transformed into the corresponding alpha-amino fatty acids in three steps . First, they are hydroxylated by the cytochrome P450 monooxygenase atnE, then oxidized to the corresponding alpha-keto acids by the NAD(P)-dependent oxidoreductase atnD, and finally converted to the alpha-amino fatty acids by the PLP-dependent aminotransferases atnH or atnJ . the alpha-amino fatty acids, 2-amino-octanoic and 2-amino-dodecanoic acids, are recognized, activated, and covalently tethered to the NRPS atnA by its fourth and sixth adenylation domains . The second module of atnA is the Thr module and contains an epimerase (E) domain responsible for the epimerization of Thr to D-allo-Thr . Additionally, despite atnA having only one epimerase domain, the first amino acid of aspercryptin A1 is D-Ser, suggesting that serine is either loaded directly as D-Ser on the first module or that the epimerase domain in the threonine module epimerizes both L-Ser and L-Thr . After condensation of the hexapeptide of aspercryptin, the C-terminal reductase (TE) domain might be involved in the reductive release and production of the aldehyde hexapeptide . Further reduction would generate aspercryptins . The variety of aspercryptins produced reflects the flexibiliy of the atnA NRPS, allowing incorporation of alanine instead of serine, valine for isoleucine, and a C10 fatty amino alcohol instead of the C12 version . AtnB seems to be involved in the selectivity for Ile versus Val by the third module . Moreover, type B, C and D aspercryptins have an additional N-terminal cichorine, acetyl and propionyl group respectively ."}]}
+{"id": "function_test_509", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKGYLTFVLHTHIPYVRKHGKWPFGEEWVFEAISETYIPLLMEFERLRDSGVKFGIVINVTPVLAEQLTDEYMKKAFEEYMERKLKAMEEDLKSGKYDEKAVSYMLNYFRKVYDYWKAINGDIIGKLRELQDQGYVEVITSAATHGYLPLLGRDEAIRAQIANGVATYEKHFGMKPKGIWLPECAYRPAGEWELPGGRKVKRQGIEKFLEEFGLRYFFVESRLIDEGPASNVYGEVLIADTEKTTLRPYWIKGSNVAVFARNRETGHQVWSAHYGYPGDFWYREFHKKAPKSGGQYWRITSKEVGLGEKEFYDPDKAMERVEEHARHFVSLVERLLREHEEKFGEKGIIVAPYDTELFGHWWFEGVKWLGRVLELLYQRGVETPTLSRFLEEYSGEKHEIELPEGSWGANSDHSTWWNEETEWTWPHIYRAEDRMVAIVSRFRGRDELTNRVIEQLARELLILEASDWQFLITTGQAKEYAKRRVLIHSRDFHRLANELVRYVKIGEFDVKLLEELEERDNPFRPVVVGPYVSENPPELEEYVEPPEVPPEKEETEEKPKVLTEKATSLALAVKKVKPVKEETREVKKKAVEASKRGKRKSSKSKRLPRKVSKKAPSKGPSDLLSIKGIGPKTFQKLKRAGVETIEDLKNANIEDLARKTGISTKRLKKFIAQVE", "output": "Catalyzes the formation of branch points in alpha-glucans by cleavage of an alpha-1,4 glycosidic bond and subsequent transfer of the cleaved-off oligosaccharide to a new alpha-1,6 position. The branch chain-length distribution of the reaction products shows degree of polymerization (DP) of 5 to 30, with two local maxima at DP 6 and DP 11. Exhibits an alpha-retaining catalytic mechanism. Does not display alpha-galactosidase or pullulanase activity, since melibiose and pullulan are not substrates. Is not able to catalyze the hydrolysis or transglycosylation of maltoheptaose, suggesting that the TK1436 protein contains neither alpha-amylase nor 4-alpha-glucanotransferase activity."}]}
+{"id": "function_test_510", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKAGATSMWASCCGLLNEVMGTGAVRGQQSGFAGATGPFRFTPNPEFSTYPPAATEGPNIVCKACGLSFSVFRKKHVCCDCKKDFCSVCSVLQENLRRCSTCHLLQETAFQRPQLMRLKVKDLRQYLILRNIPTDTCREKEDLVDLVLCHHGLGSEDDMDTSSLNSSRSQTSSFFTRSFFSNYTAPSATMSSFQGELMDGDQTSRSGVPAQVQSEITSANTEDDDDDDDEDDDDEEENAEDQNPGLSKERVRASLSDLSSLDDVEGMSVRQLKEILARNFVNYSGCCEKWELVEKVNRLYKENEENQKSYGERLQLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVFKS", "output": "E3 ubiquitin-protein ligase that regulates several biological processes through the ubiquitin-mediated proteasomal degradation of various target proteins. Ubiquitinates the caspases CASP8 and CASP10, promoting their proteasomal degradation, to negatively regulate cell death downstream of death domain receptors in the extrinsic pathway of apoptosis. May mediate 'Lys-48'-linked polyubiquitination of RIPK1 and its subsequent proteasomal degradation thereby indirectly regulating the tumor necrosis factor-mediated signaling pathway. Negatively regulates p53/TP53 through its direct ubiquitination and targeting to proteasomal degradation. Indirectly, may also negatively regulate p53/TP53 through ubiquitination and degradation of SFN. Mediates PPARGC1A proteasomal degradation probably through ubiquitination thereby indirectly regulating the metabolism of brown fat cells. Possibly involved in innate immunity, through 'Lys-48'-linked polyubiquitination of NOD1 and its subsequent proteasomal degradation."}]}
+{"id": "function_test_511", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSMEDPFFVVKGEVQKAVNTAQGLFQRWTELLQDPSTATREEIDWTTNELRNNLRSIEWDLEDLDETISIVEANPRKFNLDATELSIRKAFITSTRQVVRDMKDQMSTSSVQALAERKNRQALLGDSGSQNWSTGTTDKYGRLDRELQRANSHFIEEQQAQQQLIVEQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLDNVMKKLAKVSHMTSDRRQWCAIAILFAVLLVVLILFLVL", "output": "SNARE promoting movement of transport vesicles to target membranes. Targets endosomes to the trans-Golgi network, and may therefore function in retrograde trafficking. Together with SNARE STX12, promotes movement of vesicles from endosomes to the cell membrane, and may therefore function in the endocytic recycling pathway."}]}
+{"id": "function_test_512", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKGLGTLFLLLTACLASRADDAATLPDIQVQENFIESLIYGKWFNLAVGSTCPWLRRIKDKMSMSTLVLQEGATEAEISMTSTRWRRGVCEEISGAYEKTDIDGKFLYHKSKWNITLETYVVHTNYDEYAIFLTKKFSHYHGPTITLKLYGREPKLRDSLLLEFREVALSMGIPENSIVFMADKGECVPGDQEVKPSPHLRARRAVLPQENEGSGSEPLVTGILKKEDSCQLTYSEGPCLGMMERYHYNGTSMACETFQYGGCLGNGNNFISEKECLQTCRTVAACNLPIVQGPCRAYIKLWAFDAAQGKCIQFTYGGCKGNGNKFYSEKECKEYCGVPGDGDKTN", "output": "[Alpha-1-microglobulin]: Antioxidant and tissue repair protein with reductase, heme-binding and radical-scavenging activities. Removes and protects against harmful oxidants and repairs macromolecules in intravascular and extravascular spaces and in intracellular compartments. Intravascularly, plays a regulatory role in red cell homeostasis by preventing heme- and reactive oxygen species-induced cell damage. Binds and degrades free heme to protect fetal and adult red blood cells from hemolysis. Reduces extracellular methemoglobin, a Fe3+ (ferric) form of hemoglobin that cannot bind oxygen, back to the Fe2+ (ferrous) form deoxyhemoglobin, which has oxygen-carrying potential. Upon acute inflammation, inhibits oxidation of low-density lipoprotein particles by MPO and limits vascular damage. Extravascularly, protects from oxidation products formed on extracellular matrix structures and cell membranes. Catalyzes the reduction of carbonyl groups on oxidized collagen fibers and preserves cellular and extracellular matrix ultrastructures. Importantly, counteracts the oxidative damage at blood-placenta interface, preventing leakage of free fetal hemoglobin into the maternal circulation. Intracellularly, has a role in maintaining mitochondrial redox homeostasis. Bound to complex I of the respiratory chain of mitochondria, may scavenge free radicals and preserve mitochondrial ATP synthesis. Protects renal tubule epithelial cells from heme-induced oxidative damage to mitochondria. Reduces cytochrome c from Fe3+ (ferric) to the Fe2+ (ferrous) state through formation of superoxide anion radicals in the presence of ascorbate or NADH/NADPH electron donor cofactors, ascorbate being the preferred cofactor (By similarity). Has a chaperone role in facilitating the correct folding of bikunin in the endoplasmic reticulum compartment (By similarity).; "}]}
+{"id": "function_test_513", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEYGTRKLSDVYEVSEILGRGGFSVVRKGTRKSNNDDEKSQSQSKSQSQSQVAIKTLRRLGTSNNLPRKKDGGENSTETMMKFPTMRQVSVSDALLTNEILVMRRIVENVSPHPNVIDLYDVYEDTNGVHLVLELCSGGELFDRIVAQDKYSETEASTVVHQIVAGLEAIHRANIIHRDLKPENCLFLDVGKDSSLKIMDFGLSSVEEFTDPVVGLFGSIDYVSPEALSQGKITTKSDMWSLGVILYILLSGYPPFIAQNNRQKQQMILNGNFSFYEKTWKGISQSAKNLISSLLTVDPAKRPSAQELLSDPWVKGEKAKDDQMDPEIVSRLQRFNARRKLRAAAIASVWSSTIFLRTKKLKSLVGSYDLKEDEIENLRMHFKKICADRDNATLCEFEEVLKAMKMPSLIPFAARIFDLFDNNRDGTVDMREILCGFSSLKNSKGEDALRLCFQMYDTDRSGCITKEEVASMLRALPYDCLPTDITEPGKLDEIFDLMDANSDGKVTFDEFKAAMQRDSSLQDVVLS", "output": "Protein kinase that recognizes the calcium spiking induced by Nod factors and translates this signal to components controlling nodulation and mycorrhizal infection responses."}]}
+{"id": "function_test_514", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MVKIGSDTLAPKQLVLENKYIAACLSKPANFALSFLAQGASLKPSVVARAAINGVIACDTTTFQLLAMDGTPLSFAAAAVVVRQFQLAHNRFVKIGLRQFYKECTRRCNAFNLQKAARQSRERRAACKRILASLDADLPCSRSSRRAIVTAHYAGVATAARKSALFRQMRADKRASRALAAAMQPLVLAPPTCARIPYVCPLSSSVEESVSRRSLERCSKRVPREHASPRVASEMQPFADRPRLFSRVLLLPLSEITRAFFSRVFVPGSAMYDCATDLAHVVLDWWSITPMAHYLAMLDNFLGTPTEESVRQASTNLLEEVEAMRALCRDHRANGVFAWVTETAGTIGSTLKTAAVAPFHGAGVALKAVLTPCASATLAWGEKFFQTLKSKFFEFLKPYIQHAIYASAEIEKYWAFIHGWATKMWNNVGVELQALGDAAWWAIGITMVCGIVTLVEKLLVYLGALNAGGILCSLMLTGLLGAAGLLATGKFAEASSTLVGAMRSLIFTLFGSWKPTEASDGLTCNANALDFPLKVLETVGTGLISAPLGTLQYIGKYGQAMDQIRKGKDAIKEFVGFCMDRVADAWDYMTGRKDSFLREIASAAKVDIVYWIKQTQSVLLQAQTIAVTDIVLLDTVTHLLYKGQILQLTLAKASRTTSLDYARIVSTLIGELTKIRATCARAGSFDGRRPEPFWCYIYGKSHCGKSLFMEDVSRALLKENGHAPNDIYAKNARDSFWSGYLQHACVQVDDLSACVTRPSLESEFLQLVGSKMYSLNMAAVEDKGMSFNSSIIVTTANVYTAPTSAEITDKDAYGNRRNVVVQCRAAPDVEFDPRNPSASCEARLVHRTDESPLGNGQWRNCSAVLEDIIHHAAIHRNKENLLMENYRERSDTQHPVFVGAKSFIHRLAKEKNFAHIVCDDVLYYHDSYIDSTRVSEGTINIGMEDACIQSVVQWSELVGGVKDLGLLYAFVHAFTEGPCHVDSVEALNSEATSCQRDFFQSLSLLERIYMRLVQKQLDRIRANPDFLFSVDIKTRILQSFRHGYDEMITHGGKVLAIFAALLLVLLLYSSFFALYQTFVAGTSSALVSAGMITQLSANAGSVCTSASNPSGAASYVSSNIPIHHRWRSNYSERSYALNSNLEDKYLLDLLVWLQIPGDSIISCIRFKGRSLLLTKHQALAIPEGARVYCNYYGRGRAVQTIPLSWSYKKVREFADTEAVLFLDAQLSTMPAGREHYFNVPVERLPSVFDMNGVVMKQKRYMTDSDDSLAAFTPNQPVVNTWENSRAKLNCERQGINTFAYGGNYRNELPRSISSNCNTSPEDCGAIMTMIFEGRRVVVGMHVASGKNPQGRYMSTACLLPDYHEDLSLNSMLQYTPYDGICKEGYRQIGNIENIGARPYTSGKTAFVAVPQHLLYSPPVLQEKLPGSAQPVTIQVEVKQPAILSKDDPRIPEGTSYDPLIDGMAKFSHPMAVLDENVCNEVAQDIVESWHDCFQDLQDVSDEIAINGSTEMDYEPFNLQSSEGYPYVTQRKPGESGKIRFFEMDPYTGLKSLIPNTLPAMRYEALQRDCFTSVPEMVCIETPKDECLPLRKICIKPKTRLFSILPLEFNLLLRKKFLHFSSSLQMHRDTLPTQVGVNPYSREWGELLQRLRAQSSVAINCDYASFDGLLTGQILEKIGTMINKMYIGSEASKIQRLNLLMSIVNRKSICGARVYEVRAGIPSGCALTVLLNSIFNEFLIRFVWRTTIIGVPRERFSQYVTLLIYGDDNLIAVHPDYLPHFNGEIIRTRLADVNVIITDGSDKTAEKIEEKPLVQLDFLKRRFRKLNDGTVYAPLDLASVYTSLQNVTMGAGSIHIALQNNVHNALLELYLHGNETWFNHLRDFYRKSHAWVNLPSWREAFAFHQGQISGVTPWTPYQMFDVPVDGGRLRAMMANQGEAAFSTHLGREIYICGPKWCVSDPEHQFVVSTTPLRSADRGSGIHRAIEYPCNGVGRLPSQDWVTKFKSSAHRVTAEIRKAHASGKAIYFRDDPPYVANWCAAIGFAQGLGYDYKSMINLYHDVSVPGSDALYFYFEQRARRALPEPYIPPHLRTRVR", "output": "Picornain 3C-like protease is a thiol protease that cleaves at Gln-|-Gly or Gln-|-Ser sites in the P1 and P2 polyproteins.; "}]}
+{"id": "function_test_515", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MATWNASQIILNSMSNIIESPQSKPRPVMASNGASLFIPVTMEVPCDQGTRMWWAFLASSMVTFFGGLFIILVWRTFKYLWTVCCHCGGKNKEAQKVVNVASSQVTDGDYKPTDDKEEVGVAEVGWMTSVKDWAGVMISAQTLTGRVLVVTVFALSIGALMIYFIDSSNPIESCQNFYKDFTLQIDMAFNIFFLLYFGLRFIAANDKLWFWLEVNSVVDFFTVPPVFVSVYLNRSWLGLRFLRALRLIQFSEILQFLNILKTSNSIKLVNLCSIFISTWLTAAGFIHLVENSGDPWRNFENSQDLSYWECMYLLMVTMSTVGYGDVYAKTTLGRLFMVFFILGGLAMFASYVPEIIELIGNRKKYGGSYSAVSGRKHIVVCGHITLESVSNFLKDFLHKDRDDVNVEIVFLHNISPNLELEALFKKHFTQVEFYQGSVLNPHDLARVKIESADACLILANKYCADPDAEDASNIMRVISIKNYHPKIRIITQMLQYHNKAHLLNIPSWNWKDGDDAICLAELKLGFIAQSCLAQGLSTMLANLFSMRSFIKIEEDTWQKYYLEGVANEMYTEYLSSAFVGLSFPAVCELCFVKLKLLMIAIEYKSEKGESRILINPGNHMKIKEGTLGFFIASDAKEVKRAFFYCKACHDDITDPKRIKKCACKRLEDEQPSALSPKKKQRNGGMRHSPNTSPNMMRHDPLLMTGNDQIDNMDSSSVKRYDSTGMFHWCPAKELDKVLLTRSEAAMTVLSGHVVVCIFGDMTSALIGVRNLVMPLRASNFHYHELKHIVFVGSLDYIKREWETLHNFPKVSILPGTPLSRADLRAVNINLCDMCVILSANQNNIDDTSLQDKECILASLNIKSMQFDDSIGLLQANSQGFTPPGMERSSPDNSPLHGVARQASITTGANIPIITELVNDSNVQFLDQDDDDDPDTELYLTQPFACGTAFAVSVLDSLMSATYFNDNILTLIRTLVTGGATPELEALVAEENALRGGYSTPQTLANRDRCRVAQLALYDGPFADLGDGGCYGDLYCKALKTYNMLCFGIYRLRDAHISTPSQCTKRYVITNPPYEFELVPTDLIFCLMQFDHNASQSRASLSHSSHSSHSSSKKSSSVTSILHTASANRQNRVKARDSRDKQKMGQAEKKWYTDETENNYPRNIQIKPMSTHMANQINQYKSTSSLIPPIREVEDEC", "output": "Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity. In smooth muscles, its activation by high level of Ca(2+), caused by ryanodine receptors in the sarcoplasmic reticulum, regulates the membrane potential. In cochlea cells, its number and kinetic properties partly determine the characteristic frequency of each hair cell and thereby helps to establish a tonotopic map. Highly sensitive to both iberiotoxin (IbTx) and charybdotoxin (CTX) (By similarity)."}]}
+{"id": "function_test_516", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDVAGAGGGGAADGNIQGVPTHNGEYTQYNIFGNLFEVSRKYVPPIRPIGRGAYGIVCSAVNSETGEEVAIKKIGNAFDNRIDAKRTLREIKLLRHMDHENIVAIRDIIRPPTRENFNDVYIVYELMDTDLHQIIRSNQPLTEDHCQYFLYQLLRGLKYIHSAKVLHRDLKPSNLLLNANCDLKICDFGLARTTSETDFMTEYVVTRWYRAPELLLNCSEYTAAIDVWSVGCIFMELLNREPLFPGRDYVQQLRLITELIGSPEDHDLGFLRSDNARRYIRQLPRFARQPLDRKFPNMGPAAIDLVEHMLRFDPARRITVEEALAHPYLATLHDINDEPICHSPFEFDFEQPSFTEEHIKELIMMEAIAFNPGNVGDMMS", "output": "The CERK1, MEKK1a/b, MKK1a/b/c and MPK4a/b proteins are involved in pathogen defense. The pathway induces rapid growth inhibition, cell wall depositions and accumulation of defense-related transcripts. This protein may act redundantly with MPK4a in innate immunity triggered by pathogen-associated molecular patterns (PAMPs). May also be involved in resistance to necrotrophic fungi B.cinerea."}]}
+{"id": "function_test_517", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MALALWVFALLGSACLVSANIFEYQVDAQPLRPCELQRERAFLKRADYVPQCAEDGSFQTVQCKKDGGSCWCVDADGREVPGSRQPGRPVACLSFCQLQKQQILLSSYINSTATSYLPQCQDSGAYAPVQCDVRREQCWCVDAEGMEVYGTRRLGRPARCPGSCEIRNRRLLHGVGDKSPPQCSADGTFLPVQCKFVNTTDMMFFDLVHSYNRFPDAFVTFSSFRSRFPEVSGYCHCADSQGRELAGTGLELLLDEIYDTVFAGLDLASSFTETTLYRILQRRFLAVQLVTSGRFRCPTKCEVERFAATSFGHPYVPSCGRDGEYQAGQCQQEGLCWCVDAQGQEIPGTRRPSEPLSCAEGQSCPSERRRALSRLHLGPSGYSGQRGSFLAAERGPVSQTVPSFAASCPLPLKELFVESGILQPVVQGQKKEVTAATESLLKEGLRGIFPSRELARLALQFTANPKRLQQNLFGGRFLANVGQFNLSGALGTRGTFNFSHFFQQLGLPGFQKRQALADPAKSLSVGLDSNPATEAPEALKMGVAMNKTVVGSFGFEVNLQENRNALTFLSSLLELPEFLLFLQHAISVPEDIARDLGDVMEMALSSQGCEQTPGSLFVPSCTAEGSYEDVQCFAGECWCVDARGRELAGSRARGGRPRCPTACEKQRERMQSLLGRQPAGSSVFVPSCTREGHFLPVQCFSSDCYCVDADGQPIPGTRTAPGEPKQCPTPCQLQAEQAFLGTVRGLISNPSEPPVLSSIYIPQCSASGQWRRVQCDGPPEQAFEWYERWGAQSRSGQELTPAELLMKIMSYREAASGSFRLFIQNLYEAGQQGIFPGLARYSSLQDVPLAVLEGNLTQATGNILLEPYLFWQILNGQLPRYPGPYSDFSAPLAHLDLRSCWCVDEAGRKLEGTQTEPSKVPACPGSCEEVKLRVLQFIKEAEEIVMVSNSSQFPLGESFLAAKGIRLTDEELALPPLSPSRETFLEKFLSGSDYAIRLAAQSTFSFYQRRRVALSDAPRTSGPLQPYPYVPQCDALGSWEPVQCHAATGHCWCVDGEGAYLPASLAARSPQVLQCPTPCETSRVRGLLSAWKQAGSQVRPSPKDLFIPACTETGEFARLQASEASTWCVDPASGEAMPPGTNSSAPCPGLCEVLQRGVPSRRASPGTTPACRAEDGGFAPVQCDPAQGSCWCVLGSGEEVPGTRVAGSQPACERPQLWQTIQTRGQFQLQLPPGKVCSADYAGLLPTFQVVILDELTARGFCRIQVTTARTPVSIPVCDDSTVRVGCLSLDRLGVNVTWTLRLEDAPPASLPDLRDIEEALAGKDLVGRFADLIQSGTFQLHLDSRTFPADPSIHFLQGNSLGTSPRTRFGCVEGSRQVPATSNTSQDPLGCVRCPEGSYFQEEQCIPCPAGFYQEQTGSLACAPCPAGTTTTSVGAFSQTHCVTACQRDEAGLQCDQDGQYRASQRDRASGKAFCVDSEGRRLPWSETQAPLVDAQCLMMRKFEKLPESKVIFTADVAVLGSIVPDSESSLMQCLADCARDEACSFLTVSLEGSEGSCDFYAWTSDNIACTSSGQEEDALGTSKATSLGSLTCQVKVRPGDGVAPAVYLKKGQEFATIGQKRFEQTGFQNALSGLYSPVVFSASGASLTEAHLFCLLACDRDSCCDGFILTQVQGGPIICGLLSSPDVLLCHVRDWRDPSEAQADATCPGVTYDQDSRQGTLRLGGQEFKSLTPREGARDTFTSFQQVYLWKDSDMGSRSESMGCRRDMQPRPESPEETDLTAELFSPVDLNQVIVSENRSLPSQQHRLFKHLFSLQQAHLWCLSRCVQEPSFCQLAEITDSSPLYLTCTLYPEAQVCDDVMEASPRGCRRILPRRPNALFQRRVVLQDRVKNFYTRLPFQKLTGLSIRHKVPMADKAISSGFFECERLCDVDPCCTGFGFLNVSQLKGGEVTCLTLNSLGLQTCSEENGGSWRLLACGSPDTEVRTYPFGWYQKPAVQNDAPSFCPSAALPPVPEKVALDSWQPLPPSSVVVDPSIRNFDVAHISTAAVGDFSAARERCLLECSRHQACLVTTLQTRPGAVRCMFYADTQSCTHSLQAQNCQLLLREEATHIYRKPDIPLPGLGSSAPTVTIATHGQLLGTSQAIQLGASWKQVDQFLGVPYAAPPLAESRFRAPEPLNWTGTWDATKPRASCWQPGIRPATAPGVSEDCLYLSVFVPQSLTPNSSVLVFFHNGAEGPLAMAVDGSFLAAVGNLIVVTASYRTGVFGFLSSGSSEVSGNWGLLDQVAALTWVQTHIGVFGGDPRRVALAADRGGADVAGIHLLTSRATNSRLFRRAVLMGGSVLSPAAVIRPDRAQQQAAALAKEVGCPPRPSQKWYPASAGACQPPNDAQMQLLAVSGPFHYWGPVVDGQLLREAPARALQRPPRAKLDLLIGSSQDDGLIDRAKAVKRFEESQGRTSSKTAFYQALQNSLGGEAGDPGVQAAATWYYSLEHDTDDY", "output": "Acts as a substrate for the production of iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3) . The synthesis of T3 and T4 involves iodination of selected tyrosine residues of TG/thyroglobulin followed by their oxidative coupling . Following TG re-internalization and lysosomal-mediated proteolysis, T3 and T4 are released from the polypeptide backbone leading to their secretion into the bloodstream (By similarity). One dimer produces 7 thyroid hormone molecules (By similarity)."}]}
+{"id": "function_test_518", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLPSIVISIVLASFVSAESSITEAPTTTAEDNPYTIYPSVAKTASINGFADRIYDQLPECAKPCMFQNTGVTPCPYWDTGCLCIMPTFAGAIGSCIAEKCKGQDVVSATSLGTSICSVAGVWDPYWMVPANVQSSLSAAATAVASSSEQPVETSSEPAGSSQSVESSQPAETSSSEPAETSSSEPAETSSETSSEQPASSEPAETSSEESSTITSAPSTPEDNPYTIYPSVAKTASINGFADRIYDQLPECAKPCMFQNTGVTPCPYWDTGCLCIMPTFAGAIGSCIAEKCKGQDVVSATSLGTSICSVAGVWDPYWMVPANVQSSLSAAATAVPSSSEQSVETSSESAESSQSVESSQPAETSSEQPSETSSETSSQQLSSITSAPDSSATSSSSTTSTFIRTASINGFADKLYDQLPECAKPCMFQNTGITPCPYWDAGCLCVMPQFAGAIGSCVADSCKGQDIVSVTSLGTSVCSVAGVNAPYWMLPASVKSSLSVAATAVPTSDSASETASQEPSETSSEQPSETASQQPAETSSEESSTITSAPSTPEDNPYTIYPSVAKTASINGFADRIYDQLPECAKPCMFQNTGVTPCPYWDTGCLCIMPTFAGAIGSCIAEKCKGQDVVSATSLGSSICSVAGVWDPYWMLPANVQSSLNAAATAVATSDSASEVASASESASQVPQETSAASSQSANNSVASAAPSNSSVSAAPSSNSSGVPAAPSNNSSGASVVPSQSANNSSASAAPSNNSSSAISESVAPSSYGNSTIAQPSTSTKSDAASITGPITTDKVITNESGIVFTSTVIITHVSEYCDQTSAAAVQSSACEEQSSAKSEQASASSEQVKVITSVVWCESSIQSIESVKTSAEAAHKTEVIASCASELSSLSSAKSEAMKTVSSLVEVQKSAVAKQTSLAAVQSSAASVQLSAAHAQKSSEAVEVAQTAVAEASKAGDEISTEIVNITKTVSSGKETGVSQATVAANTHSVAIANMANTKFASTMSLLVASFVFVGLFI", "output": "Heme-binding protein involved in heme-iron utilization. The ability to acquire iron from host tissues is a major virulence factor of pathogenic microorganisms. Required for biofilm formation."}]}
+{"id": "function_test_519", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIDVNTVVEKFKSRQALIGIVGLGYVGLPLMLRYNAIGFDVLGIDIDDVKVDKLNAGQCYIEHIPQAKIAKARASGFEATTDFSRVSECDALILCVPTPLNKYREPDMSFVINTTDALKPYLRVGQVVSLESTTYPGTTEEELLPRVQEGGLVVGRDIYLVYSPEREDPGNPNFETRTIPKVIGGHTPQCLEVGIALYEQAIDRVVPVSSTKAAEMTKLLENIHRAVNIGLVNEMKIVADRMGIDIFEVVDAAATKPFGFTPYYPGPGLGGHCIPIDPFYLTWKAREYGLHTRFIELSGEVNQAMPEYVLGKLMDGLNEAGRALKGSRVLVLGIAYKKNVDDMRESPSVEIMELIEAKGGMVAYSDPHVPVFPKMREHHFELSSEPLTAENLARFDAVVLATDHDKFDYELIKAEAKLVVDSRGKYRSPAAHIIKA", "output": "Plays a role in the biosynthesis of B-band O antigen for serotype O5. Catalyzes the C-6 dehydrogenation of UDP-D-GlcNAc to UDP-N-acetylglucosaminuronic acid (UDP-D-GlcNAcA)."}]}
+{"id": "function_test_520", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MARGFQGVMLRGLGARDHQATVVDKEYIAPHFVRVRLVSPTLFDEVIVEPTSWLRFWFPDPDGSDTEFQRAYTITESDPETGRFAVDMVLHEPAGPASTWARTVEPGATIAVMSMGSRGFSVPEDPEDRPVGYLLIGDSASTPAINGIIEVVPHDIPIELYLEQHHDDDVLIPLAEHPRLRVHRVSRDDASSLAAALELRDWSNWYCWAGPEAGALKQVRTRLRDEFGFPKREVYAQAYWTEGRAMGSSRGETSTPAKPAAKTAPAKAAAKPAAASGAGTPEHAAAPAAATTGAPQAAPAPGAAQPRTPVRGRWRAEAGSRLLAPLKKPLIVSGVLQALITLIELAPFVLLVELARLLLGGAEAERLWTLGLTAVSLIGLGAVLAAAMTLWLHRVDARFAHELRGRLLTKLSRLPLGWFTRRGSASTKQLVQDDTLALHYLITHAIPDAVAAVVAPVAVLVYLFVADWRVALVLFIPVLVYLVLMSVMTIQSGSKIAQAPRWAERMGGEAGAFLEGQPVIRIFGGAAASRFRRRLDDYIDFLVSWQRPFVGKKTLMDLVTRPATFLWIILVAGVPLVVTGRMDPVNLLPFLLLGTTFGARLLGIGYGLSGIQTGMLAARRIQTVLDEPELVVRDRTGQAGTDHASGDQARPGTVELDRVSFEYRPGVPVIRDVTLTLRPGTVTALVGPSGSGKSTLAALVARFHDVTQGAIRVDGRDIRTLTADELYRRVGFVLQDAQLVHGSVAENIALAEPDAGLERIRTAARDAQIHDRITRMPDGYDSVLGAGSALSGGERQRVTIARAILADTPVLVLDEATAFADPESEYLVQQAINRLTRDRTVLVIAHRLHTITHADQIVVLDDGRIVEVGTHDELLAAGGRYRGLWDSGRYSSPDAGRPVSADAVEVGR", "output": "Part of the ABC transporter complex IrtAB involved in the import of iron-bound mycobactin (Fe-MBT) and carboxymycobactin (Fe-cMBT) . Has a preference for Fe-MBT over Fe-cMBT . Mycobactins are then reduced by the siderophore interaction domain to facilitate iron release in the bacterial cell . Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation ."}]}
+{"id": "function_test_521", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKAVLLVVAALFLAGSQARHFWQQDDPKTSWDVVKEFANKYVDAVKESGKGYVEQLDASSLGQQLNLRLSDNWDTLSTILTKLQADFGLATQEFWDTLEKETEWLKQIVSEDLQDVKHKVQPYLENFQKKVQEEVEHYREKVRPLGIELRDGARQKLQELQEKLTPLGEDLRDRTREHVDVLRTQLAPFSEEMRQRLAKRLEELKDSATLADYHAKASEHLKMLGEKAKPALEDLRQGLLPVLENLKASILSSIDQASKQLAAQ", "output": "Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility."}]}
+{"id": "function_test_522", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDKQSTFQDPKEKHRIQRDVKLSRPRKRFSFLDYVVVIFLTVVAFCVRAQRLMNPAKVVFEELRYYNYAVDYVNNKLLMDVYPPLGKLLFSLVAALTGNKYELNTLDEPGQQYPFTDVAYSMRLFTCLLGSLLVPLMYGTVYFPTKSKTAASLAALFVIFDNGLITMSRYIMIEIPALYFMSLTAFYWSVYEAQQKRPFSLRWHTSLLSTGVALGLALSTKLSAMFTFGWLLILAAFHLWNLLGDLSVPMYRIVKHLFSYIFYLIGVPITVYLAVFAVHSHIAYKASVADAFLPPEHRHALAGNRFDDQFADVAYGSLVTIRNAIPEHGYLHSSELLYPEGTEQQIISLVDEPNQNALWIIEHEHSQDNNRSNIELLKDGSVVRLRHVMTGRALHSHEHKPIVSNNDWQLEASAYGGFGFEGDANDLFRIQILEKKSKHATSNGTVETLNTKFRLIHVFANCELMSSHRRFPDWGDYQREVTCCRNCVERSTTWFIESNYHDGLPSDSRKITYRKPGFLESFVEHNKLMWLKDRKMGDGHVYESSALTWPLLLGPLRFFYEQHLQVFFMGNPFVWYSVISLVAFFVIVQIFCLARWNLGYNDFGPSAFHYNYNIGKFVVAWLLHWAPYILETDRVFLYHYLPALYFGIAALGVSWSFLGNAVFGNRTAYKALSVIIMALMFLVYRLYSPFTYMTTLTKSSCRALELKGSWNFHCNTYLDNLSDYKFSSDAGETYFEKAAPHPFVYSEDTAKKSEGDTPLNKNLNDYYPSWDQRVEAGYKLAAQQKAEQEAREAAEKAASEAAERSSSEAAASSSSESVAAASVEAERLAMEADEFNGASETVDGASVEAERSAMEAAALNNAAESTEVVGSSPESVASEQEENVAESAQARVE", "output": "Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. Required for normal cell growth and septum formation. Shown to actively O-mannosylate wsc1."}]}
+{"id": "function_test_523", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDSKESLTPGKEENPSSVLTQERGNVMDFCKILRGGATLKVSVSSTSLAAASQSDSKQQRLLVDFPKGSVSNAQQPDLSKAVSLSMGLYMGETETKVMGNDLGFPQQGQISLSSGETDLQLLEESIANLNRSTSVPENPKSSASSSVSAAPKEKEFPKTHSDVSSEQQNLKGQTGTNGGNVKLYTADQSTFDILQDLEFSSGSPGKETNQSPWKSDLLIDENCLLSPLAGEEDSFLLEGNSNEDCKPLILPDTKPKIKDNGDLVLSSSSNVTLPQVKTEKEDFIELCTPGVIKQEKLSTVYCQASFPGANIIGNKMSAISIHGVSTSGGQMYHYDMNTASLSQQQDQKPIFNVIPPIPVGSENWNRCQGSGDDNLTSLGTLNFPGRTVFSNGYSSPSMRPDVSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIIKGIQQATTGVSQETSENPANKTIVPATLPQLTPTLVSLLEVIEPEVLYAGYDSTVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQASSNLLCFAPDLIINEQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDGLKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVVENLLNYCFQTFLDKTMSIEFPEMLAEIITNQLPKYSNGNIKKLLFHQK", "output": "Receptor for glucocorticoids (GC) . Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors . Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling (By similarity). Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay (By similarity). Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth (By similarity). Mediates glucocorticoid-induced apoptosis (By similarity). Promotes accurate chromosome segregation during mitosis (By similarity). May act as a tumor suppressor (By similarity). May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic gene expression (By similarity)."}]}
+{"id": "function_test_524", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQLFHLCLIISCSCPTVQASKLCLGWLWGMDIDPYKEFGATVELLSFLPSDFFPSVRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMTLATWVGVNLEDPASRDLVVSYVNTNMGLKFRQLLWFHISCLTFGRETVIEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC", "output": "May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells. This immune regulation may predispose to chronicity during perinatal infections and prevent severe liver injury during adult infections."}]}
+{"id": "function_test_525", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "NLWQFEMLIMKIAKTSGFMFYSSYGCYCGWGGHGRPQDASDRCCFVHDCCYGKVTGVVVCGGDDPCKXQICECDRVAATCFRDNKYWFFPAK", "output": "Snake venom phospholipase A2 (PLA2) that induces significant edematogenic activity. Shows mild cytotoxicity on Trypanosoma cruzi and Leishmania infantum. Also inhibits ADP- and collagen-induced platelet aggregation. Does not show myotoxic activity."}]}
+{"id": "function_test_526", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKARRPEGRAWAQPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPTDPRRRSRNLGKVIDTLTCGFADLMGYIPLVGAPLGGAARALAHGVRVLEDSVNYATGNLPGCSFSIFLLALLSCLTIPASAYEVRNVSGVYHVTNDCSNSSIVYEAADLIMHAPGCVPCVRENNSSRCWVALTPTLAARNTSIPTTTIRRHVDLLVGAATFCSAMYVGDLCGSVFLVSQLFTFSPRRHETLQDCNCSIYPGHLSGHRMAWDMMMNWSPTTALVVSQLLRIPQTVVDMVTGAHWGVLAGLAYYSMVGNWAKVLIVMLLFAGVDGTTHVTGGATGHTTSGIASLFLPGASQKIQLINTNGSWHINRTALNCNDSLNTGFLAALFYTHKFNASGCPERLASCRSIDGFDQGWGPITYTEPGDSDQKPYCWHYAPQRCSVVSAADVCGPVYCFTPSP", "output": "[Mature core protein]: Packages viral RNA to form a viral nucleocapsid, and promotes virion budding (Probable). Participates in the viral particle production as a result of its interaction with the non-structural protein 5A (By similarity). Binds RNA and may function as a RNA chaperone to induce the RNA structural rearrangements taking place during virus replication (By similarity). Modulates viral translation initiation by interacting with viral IRES and 40S ribosomal subunit (By similarity). Affects various cell signaling pathways, host immunity and lipid metabolism (Probable). Prevents the establishment of cellular antiviral state by blocking the interferon-alpha/beta (IFN-alpha/beta) and IFN-gamma signaling pathways and by blocking the formation of phosphorylated STAT1 and promoting ubiquitin-mediated proteasome-dependent degradation of STAT1 (By similarity). Activates STAT3 leading to cellular transformation (By similarity). Regulates the activity of cellular genes, including c-myc and c-fos (By similarity). May repress the promoter of p53, and sequester CREB3 and SP110 isoform 3/Sp110b in the cytoplasm (By similarity). Represses cell cycle negative regulating factor CDKN1A, thereby interrupting an important check point of normal cell cycle regulation (By similarity). Targets transcription factors involved in the regulation of inflammatory responses and in the immune response: suppresses TNF-induced NF-kappa-B activation, and activates AP-1 (By similarity). Binds to dendritic cells (DCs) via C1QR1, resulting in down-regulation of T-lymphocytes proliferation (By similarity). Alters lipid metabolism by interacting with hepatocellular proteins involved in lipid accumulation and storage (By similarity). Induces up-regulation of FAS promoter activity, and thereby contributes to the increased triglyceride accumulation in hepatocytes (steatosis) (By similarity).; "}]}
+{"id": "function_test_527", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MASGVMVSDDVVKVFNDMKVRHQLSPEEAKKRKKAVIFCLSDDKKTIILEPGKEILQGDVGCNVEDPYKTFVKMLPRNDCRYALYDALYETKETKKEDLVFVFWAPEEASLKSKMIYASSKDAIRKRFTGIKHEWQTNTYDDINDPCNLADKLGGNTVVSLEGKSLRS", "output": "May play a role in the regulation of cell morphology and cytoskeletal organization (By similarity). Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Required for formation of the cleavage furrow during cytokinesis."}]}
+{"id": "function_test_528", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLLRDGRIPQYSIYPLPVPPMNSKTPTLGIVCSEGTISLSLEEGFEFVGVPLSGEGLKLRVEALAPSERLQEFLDDEVAYHPEENVHKVVGLSSAWLELDSEDTLIADRSEEVLLKEASYASYCGLSSIILNGPTSPMNVMRYARAVSSALNSTMNLKFLVQLAIESGHEDYFETWKMWDTIRSACGYHPRLKVALELPPACSPPIELVNRWYAEPIEMITMSCMAFVPNPNGYPVLGRKLRAIYALYLRLNPRILLWDNDAPEKIGDSPDYSIYMKHLFDSQPPAPLVEDLADSYKDYLQVPLQPLSYNLENITYEIFERDPVKYAQYEQAIFSALMDRDESSVTRIAVVGAGRGPLVDCALRAAISSSRTVDMIALEKNPNAFSMLLMRNRQDWAGKVTLVFGDMRTWNPDYKIDILVSELLGSMGDNELSPECLDGVQHVLDEETGICIPSSYISYVTPIMSPKLWSEARNMNDPNAFERQYVVLMNSFDFLAADDEFRFQSLWSFHHPNKDSEVYTKNLHNKRFASVRFQASSPGILHGFAGYFEATLYKDISLSIMPATMEAKSPDMFSWFPIYMPIKKPMYVPENSQLEFHMWRLTDGMRVWFEWCANAYLVLRNGSQIKLSSTEVHNISGKAFSCNMY", "output": "S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that can catalyze both the mono- and symmetric (type II) dimethylation of the guanidino nitrogens of arginine residues in target proteins (By similarity). Positively modulates the shk1 kinase function. May be a mediator of hyperosmotic stress response ."}]}
+{"id": "function_test_529", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVKAVAVLRGDSKITGTVTFEQANESAPTTVSWNITGHDPNAERGMHIHQFGDNTNGCTSAGPHYNPFKKTHGAPTDEVRHVGDLGNIKTDAEGNAVGSVQDKLIKVIGAESILGRTIVVHAGTDDLGRGGNEESKKTGNAGPRPACGVIGIA", "output": "Destroys radicals which are normally produced within the cells and which are toxic to biological systems."}]}
+{"id": "function_test_530", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAHELSAGSVFAGYRIERMLGAGGMGTVYLARNPDLPRSEALKVLAAELSRDLDFRARFVREADVAAGLDHPNIVAVHQRGQFEGRLWIAMQFVDGGNAEDALRAATMTTARAVYVIGEVAKALDYAHQQGVIHRDIKPANFLLSRAAGGDERVLLSDFGIARALGDTGLTSTGSVLATLAYAAPEVLAGQGFDGRADLYSLGCALFRLLTGEAPFAAGAGAAVAVVAGHLHQPPPTVSDRVPGLSAAMDAVIATAMAKDPMRRFTSAGEFAHAAAAALYGGATDGWVPPSPAPHVISQGAVPGSPWWQHPVGSVTALATPPGHGWPPGLPPLPRRPRRYRRGVAAVAAVMVVAAAAVTAVTMTSHQPRTATPPSAAALSPTSSSTTPPQPPIVTRSRLPGLLPPLDDVKNFVGIQNLVAHEPMLQPQTPNGSINPAECWPAVGGGVPSAYDLGTVIGFYGLTIDEPPTGTAPNQVGQLIVAFRDAATAQRHLADLASIWRRCGGRTVTLFRSEWRRPVELSTSVPEVVDGITTMVLTAQGPVLRVREDHAIAAKNNVLVDVDIMTPDTSRGQQAVIGITNYILAKIPG", "output": "In vitro, phosphorylates various substrates such as EmbR, PepE, MmaA4, LldD and GroEL2."}]}
+{"id": "function_test_531", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSGTFSRCMCTPAARVFWNAGQVFCTRCLSARSLLSPELQDTDLGAVGLFYKPRDKLHWKVPIGIPQVECTPSGCCWLSAVFPLARMTSGNHNFLQRLVKVADVLYRDGCLAPRHLRELQVYERGCNWYPITGPVPGMGLFANSMHVSDQPFPGATHVLTNSPLPQQACRQPFCPFEEAHSSVYRWKKFVVFTDSSLNGRSRMMWTPESDDSAALEVLPPELERQVEILIRSFPAHHPVDLADWELTESPENGFSFNTSHSCGHLVQNPDVFDGKCWLSCFLGQSVEVRCHEEHLADAFGYQTKWGVHGKYLQRRLQVRGIRAVVDPDGPIHVEALSCPQSWIRHLTLDDDVTPGFVRLTSLRIVPNTEPTTSRIFRFGAHKWYGAAGKRARAKRAAKSEKDSAPTPKVALPVPTCGITTYSPPTDGSCGWHVLAAIMNRMINGDFTSPLTQYNRPEDDWASDYDLVQAIQCLRLPATVVRNRACPNAKYLIKLNGVHWEVEVRSGMAPRSLSRECVVGVCSEGCVAPPYPADGLPKRALEALASAYRLPSDCVSSGIADFLANPPPQEFWTLDKMLTSPSPERSGFSSLYKLLLEVVPQKCGATEGAFIYAVERMLKDCPSSKQAMALLAKIKVPSSKAPSVSLDECFPTDVLADFEPASQERPQSSGAAVVLCSPDAKEFEEAAPEEVQESGHKAVHSALLAEGPNNEQVQVVAGEQLKLGGCGLAVGNAHEGALVSAGLINLVGGNLSPSDPMKENMLNSREDEPLDLSQPAPASTTTLVREQTPDNPGSDAGALPVTVREFVPTGPILCHVEHCGTESGDSSSPLDLSDAQTLDQPLNLSLAAWPVRATASDPGWVHGRREPVFVKPRNAFSDGDSALQFGELSESSSVIEFDRTKDAPVVDAPVDLTTSNEALSVVDPFEFAELKRPRFSAQALIDRGGPLADVHAKIKNRVYEQCLQACEPGSRATPATREWLDKMWDRVDMKTWRCTSQFQAGRILASLKFLPDMIQDTPPPVPRKNRASDNAGLKQLVAQWDRKLSVTPPPKPVGPVLDQIVPPPTDIQQEDVTPSDGPPHAPDFPSRVSTGGSWKGLMLSGTRLAGSISQRLMTWVFEVFSHLPAFMLTLFSPRGSMAPGDWLFAGVVLLALLLCRSYPILGCLPLLGVFSGSLRRVRLGVFGSWMAFAVFLFSTPSNPVGSSCDHDSPECHAELLALEQRQLWEPVRGLVVGPSGLLCVILGKLLGGSRYLWHVLLRLCMLADLALSLVYVVSQGRCHKCWGKCIRTAPAEVALNVFPFSRATRVSLVSLCDRFQTPKGVDPVHLATGWRGCWRGESPIHQPHQKPIAYANLDEKKMSAQTVVAVPYDPSQAIKCLKVLQAGGAIVDQPTPEVVRVSEIPFSAPFFPKVPVNPDCRVVVDSDTFVAAVRCGYSTAQLVLGRGNFAKLNQTPPRNSISTKTTGGASYTLAVAQVSAWTLVHFILGLWFTSPQVCGRGTADPWCSNPFSYPTYGPGVVCSSRLCVSADGVTLPLFSAVAQLSGREVGIFILVLVSLTALAHRMALKADMLVVFSAFCAYAWPMSSWLICFFPILLKWVTLHPLTMLWVHSFLVFCLPAAGILSLGITGLLWAIGRFTQVAGIITPYDIHQYTSGPRGAAAVATAPEGTYMAAVRRAALTGRTLIFTPSAVGSLLEGAFRTHKPCLNTVNVVGSSLGSGGVFTIDGRRTVVTAAHVLNGDTARVTGDSYNRMHTFKTNGDYAWSHADDWQGVAPVVKVAKGYRGRAYWQTSTGVEPGIIGEGFAFCFTNCGDSGSPVISESGDLIGIHTGSNKLGSGLVTTPEGETCTIKETKLSDLSRHFAGPSVPLGDIKLSPAIIPDVTSIPSDLASLLASVPVVEGGLSTVQLLCVFFLLWRMMGHAWTPIVAVGFFLLNEILPAVLVRAVFSFALFVLAWATPWSAQVLMIRLLTASLNRNKLSLAFYALGGVVGLAAEIGTFAGRLSELSQALSTYCFLPRVLAMTSCVPTIIIGGLHTLGVILWLFKYRCLHNMLVGDGSFSSAFFLRYFAEGNLRKGVSQSCGMNNESLTAALACKLSQADLDFLSSLTNFKCFVSASNMKNAAGQYIEAAYAKALRQELASLVQIDKMKGVLSKLEAFAETATPSLDIGDVIVLLGQHPHGSILDINVGTERKTVSVQETRSLGGSKFSVCTVVSNTPVDALTGIPLQTPTPLFENGPRHRSEEDDLKVERMKKHCVSLGFHNINGKVYCKIWDKSTGDTFYTDDSRYTQDHAFQDRSADYRDRDYEGVQTTPQQGFDPKSETPVGTVVIGGITYNRYLIKGKEVLVPKPDNCLEAAKLSLEQALAGMGQTCDLTAAEVEKLKRIISQLQGLTTEQALNCLLAASGLTRCGRGGLVVTETAVKIIKYHSRTFTLGPLDLKVTSEVEVKKSTEQGHAVVANLCSGVILMRPHPPSLVDVLLKPGLDTIPGIQPGHGAGNMGVDGS", "output": "[Replicase polyprotein 1ab]: Contains the activities necessary for the transcription of negative stranded RNA, leader RNA, subgenomic mRNAs and progeny virion RNA as well as proteinases responsible for the cleavage of the polyprotein into functional products.; "}]}
+{"id": "function_test_532", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSSNLIKSFGLIAIGAISGVTFTHFYYKGYQGSDVPDLTPRYTKFDSAGRALESIYDFNATKFFQYGIPGPVADQRVNHGYMSVFDRRTRNPFYTAETITQESLNQRKGNRRYSEFVPDDNIPEMFQAKLGDYRGSGYDRGHQVPAADCKFSQEAMNETFYLSNMCPQVGDGFNRNYWAYFEDWCRRLTSKYGSVTIMTGPLYLPKKNERGQWEVQYRVIGNPPNVAVPTHFFKVIIAEKSGEPTSSPSVAAFVLPNKPIADNFPLKNFAVPVEVVERASGLEILSNVPKGNRKQLCSEVVCQLNVKEFVESVKQKQKNQGK", "output": "This enzyme has both RNase and DNase activity. It degrades single-stranded DNA and RNA."}]}
+{"id": "function_test_533", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLAMSPPKPAVELDRHIDLDQAHAVASGGARIVLAPPARDRCRASEARLGAVIREARHVYGLTTGFGPLANRLISGENVRTLQANLVHHLASGVGPVLDWTTARAMVLARLVSIAQGASGASEGTIARLIDLLNSELAPAVPSRGTVGASGDLTPLAHMVLCLQGRGDFLDRDGTRLDGAEGLRRGRLQPLDLSHRDALALVNGTSAMTGIALVNAHACRHLGNWAVALTALLAECLRGRTEAWAAALSDLRPHPGQKDAAARLRARVDGSARVVRHVIAERRLDAGDIGTEPEAGQDAYSLRCAPQVLGAGFDTLAWHDRVLTIELNAVTDNPVFPPDGSVPALHGGNFMGQHVALTSDALATAVTVLAGLAERQIARLTDERLNRGLPPFLHRGPAGLNSGFMGAQVTATALLAEMRATGPASIHSISTNAANQDVVSLGTIAARLCREKIDRWAEILAILALCLAQAAELRCGSGLDGVSPAGKKLVQALREQFPPLETDRPLGQEIAALATHLLQQSPV", "output": "Catalyzes the non-oxidative deamination of L-tyrosine. Has very low phenylalanine ammonia-lyase activity (in vitro)."}]}
+{"id": "function_test_534", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNFKSTVITAMCCFFSFAVLASEKLEKPKLVVGLVVDQMRWDYLYRYYDRYSENGFKRLLNEGFSSENTLIDYVPTYTAIGHSTIYTGSVPAINGIAGNDFIIQATGQNMYCTQDDSVQAVGGEGKVGQQSPKNLLVSTITDQLKLATNFQSKVIGIAIKDRGGILPAGHFANAAYWLDGKTGDWITSTYYMKDLPKWVKGFNKEKVVDQYYKQGWKTLYPIDTYVLSTADDNLYEETFKGEKTPTFPRDLVKLKKENGYELIKSTPQGNTLTLDFAKRAIENEQLGNNPLQVTDFLAVSLSSTDYIGHQFAINSIEIEDTYLRLDRDIADFLAYLDQNIGKGNYTLFLSADHGAAHNPKFFADQKGNSGYFDTKAIRKDLNEKLASKFGVADLVKSLANYQVHLNYEVIEANDVEEDEVIAAAIKLLKKVDGVAFVVDMNEAAESSVPQILRERIINGYNFKRSGAIQLILEPQWFSGSKDGKGTTHGSWNSYDAHIPAVFLGWGVKPGKTTRQTHMTDIAPTIAQILKIEFPNGNIGTPIQEAIEQ", "output": "Catalyzes the hydrolysis of ATP coupled with the transport of calcium. Has some hydrolysis activity also with dATP, GTP, UTP, ITP and 4-nitrophenyl phosphate as substrate. No activity with ADP, CTP, acetyl dihydrogen phosphate or AMP-PNP as substrate."}]}
+{"id": "function_test_535", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPEDELPADQTVLPGGSDREGGAKNCWQDDVKDDECDSDAENEQNHDPNVEEFLQQQDTAIIYPEAPEEDQRQGTPEASGQDENGAADAFSQLLTCPYCDRGYKRFTSLKEHIKYRHEKNEDNFSCSLCSYTFAYRTQLERHMTSHKSGREQRHVTQSGGNRKFKCTECGKAFKYKHHLKEHLRIHSGEKPYECPNCKKRFSHSGSYSSHISSKKCISLMPVNGRPRSGLKTSQCPSPSLSASPGSPTRPQIRQKIENKPLQEPLSVNQIKTEPVDYEFKPIVVASGINCSTPLQNGVFSGGGQLQATSSPQGVVQAVVLPTVGLVSPISINLSDIQNVLKVALDGNVIRQVLENNQASLASKEQEAVNASSIQQGGHSVISAISLPLVDQDGTTKIIINYSLEQPSQLQVVPQNLKIENPAPTNSCKSEKLPEDLTVKSEKDKGFDGAVDGSTCLLYDDCPGDLNALPELKKHYDPEHPAQPPPPAPEAEKPEASASSARDGDLSPSQPPLKNLLSLLKAYYALNAQPNSEELSKIADSVNLPLDVVKKWFEKMQAGQIPGQSPEPPSPETGTVNIPAKSDEQPQPADGSEPQEDSASGQSPLKMTSSPVLPVGSAINGSRSCTSPPSPLNLSSARSLQGYFCVADGAQEEPQVEPLDLSLPKQQGELLERSTISSVYQNSVYSVQEEPLNLSCVKKEPQEDSCVTDSEPVVNVIPPSANPINIAIPTVTAQLPTIVAIADQNSVPCLRALAANKQTILIPQVAYTYATTVSPAMQEPPVKVIQPNGNQDERQDTSSEGVSTVEDQNDSDSTPPKKKTRKTENGMYACDLCDKIFQKSSSLLRHKYEHTGKRPHECGICKKAFKHKHHLIEHMRLHSGEKPYQCDKCGKRFSHSGSYSQHMNHRYSYCKREAEERDGTEQEQEEAGLEALMNEHVGARASPSQADSDERESLTREEDEDSEKEEEEEEDKEMEELQEEKECGNAQAEEEEEEEEEEMDGAKDEAAAKTDGAVENGAAPQAGSLEQKASESSEQLSEETTNEA", "output": "Acts as a transcriptional repressor. Binds to E-box sequences in the immunoglobulin heavy chain enhancer as well as in the regulatory regions of many other tissue-specific genes. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs (By similarity)."}]}
+{"id": "function_test_536", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRLFALVLIFFFSTRTCTEDVKSCPNGCECTDWKGYYVSCTDIATLPIFPGNTETLRLYETRLSSVPQDAFVNMVNISLIYLSVDVTLRSLEKHSFFNLKKITHVEIRNTRSLMSIDPEAFKDLPELKYLGLFNTGLTIFPALTRIHSHESNFMLEITDNLYITEIPANAFQGITKDALTVMLYSNGFTKIQHHAFNGTKLDAIYLHRNKELTELSEDMFAETISGPVLLDVSDSGVTSLPATGLESLRELSARNVWALKKLPSVKTFRHLIGADMTYPSHCCAFKNLKKKKGYLDYIICNLTAMRGQHYERSVGRITVPAVMDGTDKGIDISDPLLGNTYDHHDFLRSLHYHEFLGGHADYDMGFGDTLKNPQIATSQDFDSHYDYVVCEDGEAVTCAPAPDDFNPCEDIMGFSFLRVSVWFVSLLAVLGNMVVLFVLLTSHYKLSVSRFLMCHLAIADLCMGIYLLLIASVDLYTQSEYYNHAIDWQTGPWCTLAGFISIFATELSVYTLTTITLERWHAINFAMQLDRKLRLSHASAVMLGGWLLCLLLALMPVLGVSSYQKVSICLPMSTQNLLDQVYILFILVINIVAFVAICACYIKIYCAVHNPNYTSSRKDSSIAKRMAVLIFTNFLCIAPISFYAISAALDHPLITISNSKILLVLFYPLNSCANPFLYAIFTKAFQGDVFILLSKIGLCEQQAKLFRGQTISTRASSGDTNRRGIKTKILTRWNVQATATCHQSSVNKDNNTSRGRKCEPTANKSKHIQGMNSTMVFY", "output": "Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin . Also acts as a receptor for the heterodimeric glycoprotein hormone thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism (By similarity)."}]}
+{"id": "function_test_537", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRTLWIMAVLLVGVEGSLWQFGKMINYVMGESGVLQYLSYGCYCGLGGQGQPTDATDRCCFVHDCCYGKVTGCDPKIDSYTYSKKNGDVVCGGDDPCKKQICECDRVATTCFRDNKDTYDIKYWFYGAKNCQEKSEPC", "output": "Snake venom phospholipase A2 (PLA2) that displays edema-inducing activities (activity that is inhibited by EDTA and dexamethasone), inhibits phospholipid-dependent collagen/ADP-induced platelet aggregation, possess hypotensive as well as anticoagulant activities. In addition, this enzyme shows bactericidal activity against E.coli and S.aureus. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides."}]}
+{"id": "function_test_538", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTIRFADKADCAAITEIYNHAVLHTAAIWNDRTVDTDNRLAWYEARQLLGYPVLVSEENGVVTGYASFGDWRSFDGFRYTVEHSVYVHPAHQGKGLGRKLLSRLIDEARRCGKHVMVAGIESQNAASIRLHHSLGFTVTAQMPQVGVKFGRWLDLTFMQLQLDEHAAPDAC", "output": "Plays a role in the resistance against the toxic effects of L-methionine sulfoximine (MSX), a rare amino acid which inhibits glutamine synthetase (GlnA). Catalyzes the acetylation of MSX. It can also use L-methionine sulfone (MSO) . Also catalyzes the acylation of free L-amino acids using an acyl-CoA as acyl donor (By similarity)."}]}
+{"id": "function_test_539", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGTPPRTFLILGCFLTGPLLTLCQLPLPTIVPNRNEMVVQLNSNFTLKCSGDSEVSWQYPVTEGSHRIDIRHEENNSGLFVTVLEVGNASAAHTGMYVCYYNHTQVEDGEVEGKDIYIYVPDPDMPFVPSLPEDQFILVEEGDPTVIPCRTSDPSAEVTLVNSLDKPVYAFYDSKQGFVGNFLAGPYTCKTMVKGVEFKSDEFLIYILRATSQLPVEIEALKTVYKTGETIVVTCVVFDNEVVNLQWNYPGKVKEKGLIKLDDIKVPSQKLVYMLTIPDVLVKDTGDYECTARHATKEVKENKKVVITVHDKGFIHLEPQFSPLEAVNLHEVKNFVVDVQAYPAPKMYWLKDNVTLIENLTEIVTSSNRVQETRFQSVLKLIRAKEEDSGTILWLLKNEDEIKRYTFSLLIQVPALILDLMDDHQGSAGRQTVRCLAEGTPLPDVEWLVCKDIKKCSNDTSWTLLTNNISDIHMEAHLDERNMVESQVTFQKVEETLAVRCVARNDLGAVTRELKLVAPTLRSELTVAAAVLVLLVIVIISLIVLVIIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILGSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNLLGACTKSGPIYIITEYCFYGDLVNYLHKNRDNFLSRHPEKPKKDLDIFGMNPADESTRSYVILSFENTGEYMDMKQADTTQYVPMLERKEGSKYSDIQRSVYDRPASYKKKSLSESEVKNLLSDDGSEGLSLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGILYPGMMVDSTFYNKIKSGYRMAKPDHATNEVYEIMVKCWNNEPEKRPSFYHLSEIVESLLPGEYKKSYEKIHLDFLKSDHPAVTRMRGDCDNAYIGVTYKNEDKIKDRESGFDEQRLSADSGYITPLPDIDPVSEDELGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDSSDLVEDSFL", "output": "Tyrosine-protein kinase that acts as cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. Required for normal development of the gastrointestinal tract. Plays a role in cell migration and chemotaxis in wound healing. Plays a role in platelet activation, secretion of agonists from platelet granules, and in thrombin-induced platelet aggregation. Binding of its cognate ligands - homodimeric PDGFA, homodimeric PDGFB, heterodimers formed by PDGFA and PDGFB or homodimeric PDGFC -leads to the activation of several signaling cascades; the response depends on the nature of the bound ligand and is modulated by the formation of heterodimers between PDGFRA and PDGFRB. Phosphorylates PIK3R1, PLCG1, and PTPN11. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate, mobilization of cytosolic Ca(2+) and the activation of protein kinase C. Phosphorylates PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and thereby mediates activation of the AKT1 signaling pathway. Mediates activation of HRAS and of the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. Promotes activation of STAT family members STAT1, STAT3 and STAT5A and/or STAT5B. Receptor signaling is down-regulated by protein phosphatases that dephosphorylate the receptor and its down-stream effectors, and by rapid internalization of the activated receptor (By similarity)."}]}
+{"id": "function_test_540", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEESQSELGVEPPLSQETFSDLWKLLPENNLLSSELSLAAVNDLLLSPVTNWLDENPDDASRVPAPPAATAPAPAAPAPATSWPLSSFVPSQKTYPGSYDFRLGFLHSGTAKSVTCTYSPALNKLFCQLAKTCPVQLWVSSPPPPGTRVRAMAIYKKSEYMTEVVRRCPHHERSSDYSDGLAPPQHLIRVEGNLRAEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNFMCNSSCMGGMNRRPILTIITLEDASGNLLGRNSFEVRVCACPGRDRRTEEENFLKKGQSCPEPPPGSTKRALPTSTSSSPVQKKKPLDGEYFTLQIRGRERFEMFRELNDALELKDAQTARESGENRAHSSHLKSKKGQSPSRHKKPMFKREGPDSD", "output": "Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 (By similarity). However, this activity is inhibited when the interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 is displaced by PPP1R13L/iASPP (By similarity). In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seems to have an effect on cell-cycle regulation. Regulates the circadian clock by repressing CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER2."}]}
+{"id": "function_test_541", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLNIIYVVSLILIKFIFYKECNNNNNNYLSNIELYNYKLRKRNRILNNNINDRKSFLSDLEQNYKPLFDIYELSANFEKRRKELEKKTKGEENEIEKKKENDLEKKKENDLEKEYNDVINLLELSLSSEYKELNADVSNNDNSGHEENNKHKLNKKNSSNYKNDKSLDELIKGAILKLKQNPNIKNKNMLDYDKIFKIIKEKLINKNLASNKIRGGDNEKLKEEKKQSDISTNVEVKKDIINDQLNKGIPTKKENKDDMINKESNKEDITNEGKSNSLNNLNTLNNDGNIITKVYDHYTIVTNSNDILNDISIDASDISKNSIGGINIPFNENDNSSFTHQRYIVLSNNGEKKYKIVLMTKNPKFMDMDGIYDEEEKKESLIELNQKVNKEENTNLYDGTGTLYYGKKSKKEKENTQQKGGNNPNVDINILNNNNNNNNNNNNNNNSNNNSNSMNDEEINYNNNNNNKESPSMFRRFINFLSFSGNENETEDTLIYHNKNDNSYKNKKEGTGKNNDNNDPNNNNNKKILLNVDKLVDQYLLNLKNNHTSKQELILVLKGELDLHSKNMKNVTNNAKKNLEKYFKEHFKEFDKISYDISTPINFLCIFIPTVFDMNNMDLLKQALLILHSDLHEYVENWSFSSTYHTYEADYIKEQDSVYDRSPKKKYIKASKKLYNNKYSFLNKFLNIEPLILFAKKLNSKRSNIEKEILNFLPKELRDYSTWNLSIIRVFNAWFLAGYGNKNVKVCVVDSGADINRVDLNGNLYIPEYNEKYEMTQDFYNFMVKKSYRCLGHGSHVTGIIGGVANDLGVVGVAPNITLISLRFIDGKKYGGSFHAIKALNVCILNKAPIINASWGSSHFDVNLHLTVERLKYTLNGKGSVLIAASGNKSNDNDISPLYPATFTFPHVYSVASISRNFEISPFSNYGYKSVHILAPGHHIYSTIPNNSYKIFTGTSMAAPHVCGVSALVYSVCYNQGFIPQAEEVLDILTRTSIKIISTKKRTINDSLVNAEGAVLTTLLGGLWMQMDCYFVKFNLEKGKKKHIPVVFSAYKKGVYETDIVIAIIPIDGKSKIYGEIHIPIKIVTDVNIPNFQESPRRGKNYTIDSNEAQHDEVLSYICENALYNLYEYDSHYLLASVILFFLALLSIFVGMIYMKSRKHSDKKCSKNLIKSNYIPEMDDGMEETQQLQQERRQYFRELFGENLEKNYDQHFVQDFGQDFRQDFKLGSTPDLKQYSDIDLQNKIQQPERKTVKIIINNFEDRKKETIRRLLKGLNYDGENAKKHDFTNESISNSRKNFKFSNNTEMKKNTIKSEDVKIASDDNVNKAMNQLDDMFMK", "output": "Serine protease which plays an essential role in the shedding of AMA1, MSP1 and MSP7 from the surface of the invading merozoite; this step is essential for productive invasion and the release of the adhesion between the erythrocyte and the merozoite. May cleave TRAMP/PTTRAMP, thereby shedding TRAMP from the merozoite surface during erythrocyte invasion."}]}
+{"id": "function_test_542", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTLSGRIPLGGQVTDLGYAAGWRLVRAMPEAMAQGVFGAGARYAARNGGPEQLRRNLARVVGKPPADVPDDLIRASLASYARYWREAFRLPAMDHGRLGEQLDVIDIDHLWSALDAGRGAVLALPHSGNWDMAGVWLVQNYGPFTTVAERLKPESLYRRFVEYRESLGFEVLPLTGGERPPFEVLAERLTDNRPICLMAERDLTRSGVQVDFFGEATRMPAGPAKLAIETGAALFPVHCWFEGDGWGMRVYPELDTSSGDVTAITQALADRFAANIATYPADWHMLQPQWIADLSDERRARLGT", "output": "Catalyzes the transfer of a palmitoyl moiety from palmitoyl-CoA to the 6-position of the mannose ring linked to the 2-position of myo-inositol in phosphatidyl-myo-inositol monomannoside (PIM1) or dimannoside (PIM2)."}]}
+{"id": "function_test_543", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAAAIASSLIRQKRQAREREKSNACKCVSSPSKSKGNCEKNKLNVFSRVKLFGSKKRRRRRPEPQLKGIVTKLYSRQGYHLQLQPDGTIDGAKEEESSATVFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSEHFTPECKFKESVFENYYVTYSSMIYRQQHSGRSWFLGLNKEGEIMKGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTEFSRSGSGTPTKSRSVSGVLNGGKSMSQNDST", "output": "Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules (By similarity). Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching (By similarity). Plays a crucial role in neuron polarization and migration (By similarity). Regulates voltage-gated sodium channels transport and function (By similarity). Required for proper head development, it is involved in neural differentiation through regulation of the mek5-erk5 pathway ."}]}
+{"id": "function_test_544", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIHSVFLLMFLLTPTESYVDVGPDSVKSACIEVDIQQTFFDKTWPRPIDVSKADGIIYPQGRTYSNITITYQGLFPYQGDHGDMYVYSAGHATGTTPQKLFVANYSQDVKQFANGFVVRIGAAANSTGTVIISPSTSATIRKIYPAFMLGSSVGNFSDGKMGRFFNHTLVLLPDGCGTLLRAFYCILEPRSGNHCPAGNSYTSFATYHTPATDCSDGNYNRNASLNSFKEYFNLRNCTFMYTYNITEDEILEWFGITQTAQGVHLFSSRYVDLYGGNMFQFATLPVYDTIKYYSIIPHSIRSIQSDRKAWAAFYVYKLQPLTFLLDFSVDGYIRRAIDCGFNDLSQLHCSYESFDVESGVYSVSSFEAKPSGSVVEQAEGVECDFSPLLSGTPPQVYNFKRLVFTNCNYNLTKLLSLFSVNDFTCSQISPAAIASNCYSSLILDYFSYPLSMKSDLSVSSAGPISQFNYKQSFSNPTCLILATVPHNLTTITKPLKYSYINKCSRFLSDDRTEVPQLVNANQYSPCVSIVPSTVWEDGDYYRKQLSPLEGGGWLVASGSTVAMTEQLQMGFGITVQYGTDTNSVCPKLEFANDTKIASQLGNCVEYSLYGVSGRGVFQNCTAVGVRQQRFVYDAYQNLVGYYSDDGNYYCLRACVSVPVSVIYDKETKTHATLFGSVACEHISSTMSQYSRSTRSMLKRRDSTYGPLQTPVGCVLGLVNSSLFVEDCKLPLGQSLCALPDTPSTLTPRSVRSVPGEMRLASIAFNHPIQVDQLNSSYFKLSIPTNFSFGVTQEYIQTTIQKVTVDCKQYVCNGFQKCEQLLREYGQFCSKINQALHGANLRQDDSVRNLFASVKSSQSSPIIPGFGGDFNLTLLEPVSISTGSRSARSAIEDLLFDKVTIADPGYMQGYDDCMQQGPASARDLICAQYVAGYKVLPPLMDVNMEAAYTSSLLGSIAGVGWTAGLSSFAAIPFAQSIFYRLNGVGITQQVLSENQKLIANKFNQALGAMQTGFTTTNEAFHKVQDAVNNNAQALSKLASELSNTFGAISASIGDIIQRLDVLEQDAQIDRLINGRLTTLNAFVAQQLVRSESAALSAQLAKDKVNECVKAQSKRSGFCGQGTHIVSFVVNAPNGLYFMHVGYYPSNHIEVVSAYGLCDAANPTNCIAPVNGYFIKTNNTRIVDEWSYTGSSFYAPEPITSLNTKYVAPQVTYQNISTNLPPPLLGNSTGIDFQDELDEFFKNVSTSIPNFGSLTQINTTLLDLTYEMLSLQQVVKALNESYIDLKELGNYTYYNKWPWYIWLGFIAGLVALALCVFFILCCTGCGTNCMGKLKCNRCCDRYEEYDLEPHKVHVH", "output": "[Spike protein S1]: Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection (By similarity). Interacts with host DPP4 to mediate virla entry.; "}]}
+{"id": "function_test_545", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPPSSSITQEDKATIRKYIPKSTNKIIAAAVVKLYVAYPDPNKWNYTGLCGALVLSYDTTAKCCWFKLVDVVNNSGIIWDQELYQNMDYRQDRTFFHSFELDKCLAGFSFANETDAQKFYKKVLDKGCHPESIENPVLSFITRKGSSRHAPNNSNIQPPSAAPPVPGKENYNAVGSKSPNEPELLNSLDPSLIDSLMKMGISQDQIAENADFVKAYLNESAGTPTSTSAPPIPPSIPSSRPPERVPSLSAPAPPPIPPPSNGTVSSPPNSPPRPIAPVSMNPAINSTSKPPLPPPSSRVSAAALAANKKRPPPPPPPSRRNRGKPPIGNGSSNSSLPPPPPPPRSNAAGSIPLPPQGRSAPPPPPPRSAPSTGRQPPPLSSSRAVSNPPAPPPAIPGRSAPALPPLGNASRTSTPPVPTPPSLPPSAPPSLPPSAPPSLPMGAPAAPPLPPSAPIAPPLPAGMPAAPPLPPAAPAPPPAPAPAPAAPVASIAELPQQDGRANLMASIRASGGMDLLKSRKVSASPSVASTKTSNPPVEAPPSNNLMDALASALNQRKTKVAQSDEEDEDDDEWD", "output": "Has a role in regulating actin assembly, so regulating polarized growth."}]}
+{"id": "function_test_546", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "AAKYCKLPVRYGPCKKKIPSFYYKWKAKQCLPFDYSGCGGNANRFKTIEECRRTCVG", "output": "Serine protease inhibitor homolog that blocks voltage-gated potassium channels (Kv)."}]}
+{"id": "function_test_547", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSWALEMADTFLDTMRVGPRTYADVRDEINKRGREDREAARTAVHDPERPLLRSPGLLPEIAPNASLGVAHRRTGGTVTDSPRNPVTR", "output": "Plays a role in the inhibition of host immune response. Binds specifically to transporters associated with antigen processing (TAP), thereby blocking peptide-binding and translocation by TAP as well as subsequent loading of peptides onto MHC class I molecules. Empty MHC I molecules are retained in the endoplasmic reticulum and ultimately directed to proteasomal degradation. In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes."}]}
+{"id": "function_test_548", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRSTYLREYKLVVVGDGGVGKSALTIQLIQSHFVDEYDPTIEDSYRKKCEIDGEGALLDVLDTAGQEEYSAMREQYMRTGEGFLLVYNITSRSSFDEISTFYQQILRVKDKDTFPVVLVANKCDLEAERVVSRAEGEQLAKSMHCLYVETSAKLRLNVEEAFYSLVRTIRRYNKSEEKGFQNKQAVQTAQVPASTAKRASAVNNSKTEDEVSTKCCVIC", "output": "Participates in the process of sexual differentiation and the determination of cell shape. Essential for mating and for recognition of the mating pheromone, but not for vegetative growth. Does not regulate the intracellular cAMP level. Regulates two downstream pathways, namely the byr2/byr1/spk1 mitogen-activated protein kinase cascade and the cdc42 small G protein pathway. The former is relevant to mating and sporulation, whereas the latter is relevant to mating, cell growth and cell morphology."}]}
+{"id": "function_test_549", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKALILVGGYGTRLRPLTLSIPKPLVDFCNKPILLHQVEALASAGVDHVILAVSYMSQMLEKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETAEPFFVLNSDVICDFPFQAMVQFHRHHGQEGSILVTKVEEPSKYGVVVCEADTGRIHRFVEKPQVFVSNKINAGMYILSPAVLQRIQLQPTSIEKEIFPVMAKEGQLYAMELQGFWMDIGQPKDFLTGMCLFLQSLRQKQPEQLCSGPGIVGNVLVDPSARIGKNCSIGPNVSLGPGVVVEDGVCIRRCTVLRDARIRSHSWLESCIVCWRCRVGQWVRMENVTVLGEDVIVNDELYLNGASVLPHKSIGESVPEPGIIM", "output": "Catalyzes the formation of GDP-mannose, an essential precursor of glycan moieties of glycoproteins and glycolipids."}]}
+{"id": "function_test_550", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSKINKYGLELHWAPEFPWMFEDAEEKLDNPSSSEVDIVCSTTAQKLETGGICPENHVMVDCRRLLKQECCVQSSLIREIVMNTRPYDLEVLLQDALQSREAVLVTPPLGMSLEACYVRGCNPNGWTMGLFRRRSVCNTGRCAVNKHVAYQLYMIDPAGVCFGAGQFVGWVIPLAFMPVQSRKFIVPWVMYLRKCGEKGAYNKDHKRGGFEHVYNFKVEDAYDLVHDEPKGKFSKKAYALIRGYRGVKPLLYVDQYGCDYTGGLADGLEAYADKTLQEMKALFPIWSQELPFDVTVAWHVVRDPRYVMRLQSASTIRSVAYVANPTEDLCDGSVVIKEPVHVYADDSIILRQHNLVDIMSCFYMEADAVVNAFYGVDLKDCGFVMQFGYIDCEQDLCDFKGWVPGNMIDGFACTTCGHVYETGDLLAQSSGVLPVNPVLHTKSAAGYGGFGCKDSFTLYGQTVVYFGGCVYWSPARNIWIPILKSSVKSYDGLVYTGVVGCKAIVKETNLICKALYLDYVQHKCGNLHQRELLGVSDVWHKQLLLNRGVYKPLLENIDYFNMRRAKFSLETFTVCADGFMPFLLDDLVPRAYYLAVSGQAFCDYAGKICHAVVSKSKELLDVSLDSLGAAIHYLNSKIVDLAQHFSDFGTSFVSKIVHFFKTFTTSTALAFAWVLFHVLHGAYIVVESDIYFVKNIPRYASAVAQAFRSVAKVVLDSLRVTFIDGLSCFKIGRRRICLSGSKIYEVERGLLHSSQLPLDVYDLTMPSQVQKTKQKPIYLKGSGSDFSLADSVVEVVTTSLTPCGYSEPPKVADKICIVDNVYMAKAGDKYYPVVVDGHVGLLDQAWRVPCAGRCVTFKEQPTVNEIASTPKTIKVFYELDKDFNTILNTACGVFEVDDTVDMEEFYAVVIDAIEEKLSPCKELEGVGAKVSAFLQKLEDNSLFLFDEAGEEVLAPKLYCAFTAPEDDDFLEESGVEEDDVEGEETDLTVTSAGEPCVASEQEESSEILEDTLDDGPCVETSDSQVEEDVQMSDFVDLESVIQDYENVCFEFYTTEPEFVKVLDLYVPKATRNNCWLRSVLAVMQKLPCQFKDKNLQDLWVLYKQQYSQLFVDTLVNKIPANIVVPQGGYVADFAYWFLTLCDWQCVAYWKCIKCDLALKLKGLDAMFFYGDVVSHVCKCGESMVLIDVDVPFTAHFALKDKLFCAFITKRSVYKAACVVDVNDSHSMAVVDGKQIDDHRITSITSDKFDFIIGHGMSFSMTTFEIAQLYGSCITPNVCFVKGDIIKVSKRVKAEVVVNPANGHMAHGGGVAKAIAVAAGQQFVKETTDMVKSKGVCATGDCYVSTGGKLCKTVLNVVGPDARTQGKQSYALLERVYKHLNKYDCVVTTLISAGIFSVPSDVSLTYLLGTAKKQVVLVSNNQEDFDLISKCQITAVEGTKKLAERLSFNVGRSIVYETDANKLILSNDVAFVSTFNVLQDVLSLRHDIALDDDARTFVQSNVDVVPEGWRVVNKFYQINGVRTVKYFECPGGIDICSQDKVFGYVQQGSFNKATVAQIKALFLDKVDILLTVDGVNFTNRFVPVGESFGKSLGNVFCDGVNVTKHKCDINYKGKVFFQFDNLSSEDLKAVRSSFNFDQKELLAYYNMLVNCSKWQVVFNGKYFTFKQANNNCFVNVSCLMLQSLNLKFKIVQWQEAWLEFRSGRPARFVSLVLAKGGFKFGDPADSRDFLRVVFSQVDLTGAICDFEIACKCGVKQEQRTGVDAVMHFGTLSREDLEIGYTVDCSCGKKLIHCVRFDVPFLICSNTPASVKLPKGVGSANIFKGDKVGHYVHVKCEQSYQLYDASNVKKVTDVTGNLSDCLYLKNLKQTFKSVLTTYYLDDVKKIEYKPDLSQYYCDGGKYYTQRIIKAQFKTFEKVDGVYTNFKLIGHTVCDILNAKLGFDSSKEFVEYKVTEWPTATGDVVLATDDLYVKRYERGCITFGKPVIWLSHEQASLNSLTYFNRPLLVDENKFDVLKVDDVDDGGDISESDAKEPKEINIIKLSGVKKPFKVEDSVIVNDDTSEIKYVKSLSIVDVYDMWLTGCRCVVRTANALSRAVNVPTIRKFIKFGMTLVSIPIDLLNLREIKPVFNVVKAVRNKISACFNFIKWLFVLLFGWIKISADNKVIYTTEVASKLTCKLVALAFKNAFLTFKWSVVARGACIIATIFLLWFNFIYANVIFSDFYLPKIGFLPTFVGKIAQWIKNTFSLVTICDLYSIQDVGFKNQYCNGSIACQFCLAGFDMLDNYKAIDVVQYEADRRAFVDYTGVLKIVIELIVSYALYTAWFYPLFALISIQILTTWLPELFMLSTLHWSVRLLVSLANMLPAHVFMRFYIIIASFIKLFSLFRHVAYGCSKSGCLFCYKRNRSLRVKCSTIVGGMIRYYDAMANGGTGFCSKHQWNCIDCDSYKPGNTFITVEAALDLSKELKRPIQPTDVAYHTVTDVKQVGCYMRLFYDRDGQRT", "output": "The papain-like proteinase 1 (PL1-PRO) and papain-like proteinase 2 (PL2-PRO) are responsible for the cleavages located at the N-terminus of the replicase polyprotein. In addition, PLP2 possesses a deubiquitinating/deISGylating activity and processes both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains from cellular substrates. Antagonizes innate immune induction of type I interferon by blocking the phosphorylation, dimerization and subsequent nuclear translocation of host IRF-3 (By similarity).; "}]}
+{"id": "function_test_551", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAPVVQQPAPSFKKTAVVDGVFEEVTLEQYKGKWVLLAFIPLAFTFVCPSEIIAYSEAVKKFAEKDAQVLFASTDSEYTWLAWTNVARKDGGIGKVDFPVLADTNHSLSRDYGVLIEEEGVALRGIFLIDPKGVLRQITINDLPVGRSVEESLRLLEAFQFTEKYGEVCPANWHPGDETIKPSPEASKEYFNKVNK", "output": "Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Also involved in the correct composition of the hyphal cell wall."}]}
+{"id": "function_test_552", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDPYKHRPSSAFNSPFWTTNSGAPVWNNNSSLTVGPRGQYLLEDYHLVEKLANFDRERIPERVVHARGASAKGFFEVTHDISHLTCADFLRAPGVQTPVIVRFSTVIHERGSPETLRDPRGFAVKFYTREGNFDLVGNNFPVFFIRDGMKFPDMVHALKPNPKSHIQENWRILDFFSHHPESLHMFTFLFDDLGVPQDYRHMEGSGVNTYTLINKAGKAHYVKFHWKPTCGVKCLLEDEAIKVGGANHSHATQDLYDSIAAGNYPEWKLFIQTIDPDHEDKFDFDPLDVTKTWPEDILPLQPVGRLVLNKNIDNFFAENEQLAFCPAIVVPGIYYSDDKLLQTRIFSYSDTQRHRLGPNYLQLPANAPKCAHHNNHHEGFMNFMHRDEEINYFPSRYDPVRHAEMFPIPPAVCTGRREKCIIEKENNFKQPGERYRSWAADRQERFICRWVDALSDPRVTHEIRSIWISYWSQADKSVGQKLASLLNVRPSI", "output": "Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide."}]}
+{"id": "function_test_553", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDQDLDGAERGERGGGSEELLQEEINEGRLTAREALQTWINNGEIHPWVLAGMLSMGVGMLLGVYCQLPDTLIWILMFQLCLYWGLGETSRELDKDSWQWVRSVFIIAILGTLTMAGTALADDDQSTLIPNITKIPTKDTEPGCTYPWILILLILAFILGILGIILVLRRSNSEDILAARDTIDWWLSANQEIPPKFAFPIILISSPLAGIIGYYVMERHLEIFKKGCQICGSLSSMWGMLLEEIGRWLARREWNVSRVMVILLISFSWGMYVNRVNASGSHVAMVTSPPGYRIVNDTSQAPWYCFSSAPIPTCSSSQWGDKYFEEKINETLVKQVYEQAAKHSRATWIEPDLLEEAVYELALLSANDSRQVVVENGTDVCSSQNSSTNKGHPMTLLKLRGQVSETWIGNSSLQFCVQWPYVLVGLNNSDSNISFNSGDWIATNCMHPITLNKSAQDLGKNFPRLTFLDGQLSQLKNTLCGHNTNCLKFGNKSFSTNSLILCQDNPIGNDTFYSLSHSFSKQASARWILVKVPSYGFVVVNDTDTPPSLRIRKPRAVGLAIFLLVLAIMAITSSLVAATTLVNQHTTAKVVERVVQNVSYIAQTQDQFTHLFRNINNRLNVLHHRVSYLEYVEEIRQKQVFFGCKPHGRYCHFDFGPEEVGWNNSWNSKTWNDLQDEYDKIEEKILKIRVDWLNSSLSDTQDTFGLETSIFDHLVQLFDWTSWKDWIKIIIVIIVLWLLIKILLGMLRSCAKVSQNYQHLPAEEEDGDTEPESSPARGDPASGSLYENWLNKIGESKNDAYRVWTEEYNSLRILFATCRWDLLTPQLLQLPFFLLTLLLKLLWDIFRHAPILNLKGWTVGQGGTSGQQQPPDFPYVNWTGSREQNNPEGGLDSGAWYEGLRGSQ", "output": "The surface protein (SU) attaches the virus to the host cell by binding to its receptor. This interaction triggers the refolding of the transmembrane protein (TM) and is thought to activate its fusogenic potential by unmasking its fusion peptide. Fusion occurs at the host cell plasma membrane (By similarity).; "}]}
+{"id": "function_test_554", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAAGSITTLPALPEDGGSSAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYSSWYVALKRTGQYKLGPKTGPGQKAILFLPMSAKS", "output": "Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity). Also acts as an integrin ligand which is required for FGF2 signaling (By similarity). Binds to integrin ITGAV:ITGB3 (By similarity). Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (By similarity). Functions as a potent mitogen in vitro (By similarity). Can induce angiogenesis (By similarity). Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation (By similarity)."}]}
+{"id": "function_test_555", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGNGNSALLGTDLDKFEKIRLKRGGKKCYRLKHLCWCKGELDRFGLSDKLLETQQGCEKILSVCWPLYDQGSDNLKALVGTVCVVACIHAGIEIKSTQDALKKLKVITRKEEKQEDESKNFPVQRDAAGQYQYTPISPRIIQTWVKTVEEKKWKPEVIPLFSALTEGAISHDLNIMLNAVGDHQGAMQVLKDVINEQAAEWDLTHPQQQPAQPGGGLRTPSGSDIAGTTSTVEEQLAWMNMQQNAINVGTIYKSWIILGMNRLVKSHCPISITDVRQGPKEAFKDYVDRFYNVMRAEQASGEVKMWMQQHLLIENANPECKQILRSLGKGATLEEMLEACQGVGGPQHKARLMAEMMRTVVGQSQNFVQQRGPQRGPVRQPTGRKPICFNCNKEGHVARFFKAPRRKGCWNCGAMDHQKAQCPKPAQQQRVNFLGYGPWGPSKPGNYPAQEVTPTAPPLEEKPLQKTLSTYQKLGRGLRQKMKEEKREEDFHSLSTLFQEDQ", "output": "Matrix protein p17 targets Gag and Gag-Pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus. Also mediates nuclear localization of the preintegration complex. Implicated in the release from host cell mediated by Vpu (By similarity).; "}]}
+{"id": "function_test_556", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSTAGKVIKCKAAVLWEVMKPFSIEDVEVAPPKAYEVRIKMVTVGICGTDDHVVSGTMVTPLPVILGHEAAGIVESVGEGVTTVEPGDKVIPLALPQCGKCRICKTPERNYCLKNDVSNPRGTLQDGTSRFTCRGKPIHHFLGVSTFSQYTVVDENAVAKIDAASPMEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAVYGGFKSKEDIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLRSGKSIRTILTF", "output": "Alcohol dehydrogenase. Oxidizes primary as well as secondary alcohols. Ethanol is a very poor substrate."}]}
+{"id": "function_test_557", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGQFISFMQEIPIFLQEALNIALVAVSLICIVKGLVNLYRCGLFQLMVFLVLAGRSCSEETFKIGMHTQFQEVSLSLSALLTNQSHELPMLCLANKTHLYLKSGRSSFKINIDSVTVLTRSADVFVHSPKLGSCFESDEEWVVAWWIEAIGHRWDQDPGLLCRNKTKTEGKLIQINISRADGNVHYGWRLKNGLDHIYRGREEPCFEGEQCLIKIQPEDWPTDCKADHTNTFRFLSRSQKSIAVGRTLKAFFSWSLTDPLGNVPPGGYCLEKWMLVASELKCFGNTAIAKCNQNHDSEFCDMLRLFDYNKNAIKTLNEETKTRVNVLSHTINALISDNLLMKNKIRELMSVPYCNYTRFWYVNHTLSGQHSLPRCWMIRNNSYLNSSEFRNEWILESDFLISEMLSKEYSERQGRTPITLVDICFWSTVFFTSTLFLHLIGFPTHEHIRGEGCPLPHRLNSMGGCRCGKYLPLKKPTIWHRRH", "output": "[Glycoprotein G2]: Class I viral fusion protein that directs fusion of viral and host endosomal membranes, leading to delivery of the nucleocapsid into the cytoplasm. Membrane fusion is mediated by irreversible conformational changes induced upon acidification in the endosome.; "}]}
+{"id": "function_test_558", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGLSYGIFICFLLLGGMELCCPQTIWPTETYYPLTSRPPVMVDCLESQLVVTVSKDLFGTGKLIRPADLTLGPENCEPLVSMDTDDVVRFEVGLHECGSRVQVTDNALVYSTFLIHSPRPAGNLSILRTNRAEVPIECHYPRHSNVSSQAILPTWVPFRTTMLFEEKLVFSLRLMEEDWGSEKQSPTFQLGDIAHLQAEVHTGSHMPLRLFVDHCVATLTPDRNAFLHHKIVDFHGCLVDGLYNSSSAFKAPRPRPETLQFTVDVFHFAKDSRNTIYITCHLKVTPADRVPDQLNKACSFIKSTKRWYPVEGSADICRCCNKGSCGLPGRSRRLSHLERGWRKSVSHTRNRRHVTEEAEITVGPLIFLGKASDHGIEGSTSPHTSVMLGLGLATVVSLTLATIVLVLAKRHRTASHPVICPASVSQ", "output": "Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation."}]}
+{"id": "function_test_559", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQQQSELQPPAPSEDIWKKFELLPTPPLSPSRRSGLCSPSYVAVTPFSPRGDNDGGGGSFSTADQLEMVTELLGGDMVNQSFICDPDDETFIKNIIIQDCMWSGFSAAAKLVSEKLASYQAARKDSSSPNPARGHSVCSTSSLYLQDLSAAASECIDPSVVFPYPLNDSSSPKSCASPDSSAFSPSSDSLLSSTESSPQASPEPLVLHEETPPTTSSDSEEEQEDEEEIDVVSVEKRQAPSKRSESGSPSAGGHSKPPHSPLVLKRCHVSTHQHNYAAPPSTRKDYPAAKRVKLDSVRVLRQISNNRKCTSPRSSDTEENDKRRTHNVLERQRRNELKRSFFALRDQIPELENNEKAPKVVILKKATAYILSVQGEEQKLTSEKDLLRKRREQLKHKLEQLRNSCA", "output": "Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform (By similarity)."}]}
+{"id": "function_test_560", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MENRWQVMIVWQVDRMRIRTWKSLVKHHMYVSGKARGWFYRHHYESPHPRISSEVHIPLGDARLVITTYWGLHTGERDWHLGQGVSIEWRKKRYSTQVDPELADQLIHLYYFDCFSDSAIRKALLGHIVSPRCEYQAGHNKVGSLQYLALAALITPKKIKPPLPSVTKLTEDRWNKPQKTKGHRGSHTMNGH", "output": "Counteracts the innate antiviral activity of host APOBEC3F and APOBEC3G. Forms a complex with host APOBEC3F and APOBEC3G thus preventing the entry of these lethally hypermutating enzymes into progeny virions. Recruits an active E3 ubiquitin ligase complex composed of elongin BC, CUL5, and RBX2 to induce polyubiquitination of APOBEC3G and APOBEC3F. In turn, they are directed to the 26S proteasome for degradation. Vif interaction with APOBEC3G also blocks its cytidine deaminase activity in a proteasome-independent manner, suggesting a dual inhibitory mechanism. May interact directly with APOBEC3G mRNA in order to inhibit its translation. Seems to play a role in viral morphology by affecting the stability of the viral nucleoprotein core. Finally, Vif also contributes to the G2 cell cycle arrest observed in HIV infected cells."}]}
+{"id": "function_test_561", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRQSVTSSSSCSKLYAIKATISLPRLFYRRLRTMAPRVASHFLGGNSLDKAPAGKVKDYIASHGGHTVITSILIANNGIAAVKEIRSIRKWAYETFNNERAIKFTVMATPDDLKVNADYIRMADQYVEVPGGSNNNNYANVELIVDIAERMNVHAVWAGWGHASENPKLPEMLSASSKKIVFIGPPGSAMRSLGDKISSTIVAQSARVPCMSWSGNELDQVRIDEETNIVTVDDDVYQKACIRSAEEGIAVAEKIGYPVMIKASEGGGGKGIRQVTSTEKFAQAFQQVLDELPGSPVFVMKLAGQARHLEVQILADQYGNNISLFGRDCSVQRRHQKIIEEAPVTIAPAATFHEMERAAVRLGELVGYASAGTIEYLYEPENDRFYFLELNPRLQVEHPTTEMVSGVNLPAAQLQVAMGLPLSRIPHIRELYGLPRDGDSEIDFFFQNPESFKVQKVPTPKGHCVACRITSEDPGEGFKPSSGMIKDLNFRSSSNVWGYFSVGTAGGIHEFADSQFGHIFSFAESRESSRKSMVVALKELSIRGDFRTTVEYLVRLLETKEFSENEFTTGWLDRLIAQKVTSARPDKMLAVVCGALVRAHATADTQYRAFKSYLERGQVPSREFLKNVYDIEFIYDNTRYRFTASRSSPGSYHLFLNGSRCTAGVRSLTDGGLLVLLNGHSYTVYYRDEVTGTRISIDNLSCMLEQENDPTQLRTPSPGKLVRFLVETGEHIKAGEAYAEVEVMKMIMPLVATEDGVVQLIKQPGASLDAGDILGILTLDDPSRVTHALPFDGQLPNWGEPQIAGNKPCQRYHALLCILLDILKGYDNQIILNSTYNEFVEVLRNHELPYSEWSAHYSALVNRISPVLDKLFVSIIEKARSRKAEFPAKQLEVAIQTYCDGQNLATTQQLKVQIAPLLKIISDYKDGLKVHEYNVIKGLLEEYYNVEKLFSGINKREEDVILRLRDENKDDVDKVIALALSHSRIGSKNNLLITILDLMKSEPSTFVSLYFNDILRKLTDLDSRVTSKVSLKARELLITCAMPSLNERFSQMEHILKSSVVESHYGDAKFSHRTPSLDILKELIDSKYTVFDVLPAFFCHTDPWVSLAALEVYVRRAYRAYSVLEINYHTEAGTPYVLTWRFQLHSSGAPGLGANSTNGSNFPASTTPSYENSNRRLQSVSDLSWYVNKTDSEPFRFGTMIAAETFDELENNLALAIDRLPLSRNYFNAGLTLDGNSSSANDNTQELTNVVNVALTSTGDLDDSAIVSKLNQILSDFRDDLLEHNVRRVTIVGGRINKSAYPSYYTYRVSAEQKDGNLVHYNEDERIRHIEPALAFQLELGRLSNFNIEPVFTDNHNIHVYRATAKNMDTDKRFFTRALVRPGRLRDEIPTAEYLISETHRLINDILDALEVIGHEQTDLNHIFINFTPAFGLAPKQVEAALGGFLERFGRRLWRLRVTAAEIRIICTDPSTNTLFPLRVIISNVSGFVVNVEIYAEVKTENNSWIFKSIGQPGSMHLRPISTPYPTKEWLQPRRYKAQLMGTTFVYDFPELFRRAFTDSWKKVPNGRSKVTIPQNMFECKELVADEHGVLQEVNREPGTNSCGMVAWCITVKTPEYPNGRKIIVVANDITFQIGSFGPQEDEYFYKVTQLARQRGIPRIYLAANSGARIGVADEIVPLFNIAWVDPDSPEKGFDYIYLTPEAYERLQKENPNILTTEEVVTETGELRHKITTIIGSSEGLGVECLRGSGLIAGVTSRAYNDIFTCTLVTCRAVGIGAYLVRLGQRAVQIEGQPIILTGAPALNKVLGREVYTSNLQLGGTQVMHRNGISHLTSQDDFDGISKIVNWISYIPDKRNNPVPISPSSDTWDRDVEFYPSQNGYDPRWLIAGKEDEDSFLYGLFDKGSFQETLNGWAKTVVVGRARMGGIPTGVIAVETRTIENTVPADPANPDSTEQVLMEAGQVWYPNSAFKTAQAINDFNHGEQLPLFILANWRGFSGGQRDMFNEVLKYGSYIVDALASYKQPVFVYIPPFSELRGGSWVVVDPTINEDQMEMYADEESRAGVLEPEGMVSIKFRREKLLSLMRRCDHKYASLCNELKRDDLSADDLSTIKVKLMEREQKLMPIYQQISIHFADLHDRVGRMVAKKVVRKPLKWTEARRFFYWRLRRRLNEHYALQKITQLIPSLTIRESREYLQKWYEEWCGKQDWDESDKSVVCWIEEHNDDLSKRTQELKSTYYSERLSKLLRSDRKGMIDSLAQVLTELDENEKKELAGKLASVN", "output": "Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase."}]}
+{"id": "function_test_562", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRAAESGADARVRPVDRVEPADAPAGDAGGLRAAVPGDGGSAVRPGDARLDVLVPPGLVDEPAAGALPGGGQRAPGAGRADGGDVRPVGGRDADGAPRFDQPVPPGGYLWWYVDAVSDDGRHGLTFIAFVGSVFSPYYAWAGGPKADRADPENHCALNIALYGDAGKRWTMTERGRRWMRRSRDEFVIGPSRLHWDGESLLVEFDEVGVPIPRRVKGRVRVWPKALCRFVTSLDSGGRHRWGPIAPCSRIEVELDSPRVRWSGHAYLDSNEGDEPIDRPFREWDWSRATMADSSTAVIYDVRQKRDGDRVIAERFLLDGSTESFEAPPRQPLPTTLWRIGRTMRTEPGVPALVEQTLEDTPFYARSMVRSGLLGEVVTSVHETMLLPRVITLPVRLMLPWRMPRRA", "output": "Involved in the biosynthesis of carotenoids spheroidene and spirilloxanthin. Catalyzes the hydration of neurosporene to the corresponding hydroxylated carotenoids 1-HO-neurosporene and 1,1'-(HO)2-neurosporene and that of lycopene to 1-HO-lycopene and 1,1'-(HO)2-lycopene. Can also act on demethylspheroidene, spheroidene, 1-HO-3,4-didehydrolycopene and geranylgeraniol."}]}
+{"id": "function_test_563", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPKSPPRFLNSPLSDFFIKWMSRINTWMYRRNDGEGLGGTFQKIPVALLTTTGRKTGQPRVNPLYFLRDGGRVIVAASKGGAEKNPMWYLNLKANPKVQVQIKKEVLDLTARDATDEERAEYWPQLVTMYPSYQDYQSWTDRTIPIVVCEP", "output": "Involved in a F420-dependent anti-oxidant mechanism that protects M.tuberculosis against oxidative stress and bactericidal agents. Catalyzes the F420H(2)-dependent two-electron reduction of quinones to dihydroquinones, thereby preventing the formation of cytotoxic semiquinones obtained by the one-electron reduction pathway . In vitro, catalyzes the reduction of both benzoquinone and naphthoquinone analogs; since menaquinone is the sole quinone electron carrier in the respiratory chain in M.tuberculosis, the physiological electron acceptor for Fqr-mediated F420H(2) oxidation is therefore likely to be the endogenous menaquinone found in the membrane fraction of M.tuberculosis . Is able to use F420 species with two and five glutamate residues in its polyglutamate tail . Cannot use NADH or NADPH instead of F420H(2) as the electron donor .; "}]}
+{"id": "function_test_564", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MVPFRWGLLLGCLGSALGPGAQAQFPRVCMTVGSLQAKECCPPLGAEPSNVCGSLEGRGRCAEVQADTRPWSGPYVLRNQDDRERWPRKFFDRTCRCTGNFAGYNCGDCKFGWTGPNCDQKKPLVVRQNIHSLTAQEREQFLGALDLAKNTPHPDYVITTQHWLGLLGPNGTQPQIANCSIYDLFVWLHYYSVRDTLLGPGRPYKAIDFSHQGPAFVTWHRYHLLWLERALQRLTGNESFAVPYWNFATGRNECDVCTDQLLGAARPDDPTLISQNSRFSSWEIVCDSLDDYNRRVTLCNGTYEGLLRRNQVGRNSEKLPSLKDIEDCLSLKQFDNPPFFQNSTFSFRNALEGFDKADGTLDSQVMSLHNLVHSFLNGTSALPHSAANDPVFVVLHSFTDAIFDEWMKRFSPPVDAWPQELAPIGHNRMYNMVPFFPPVTNEELFLTADQLGYSYAIDLPVSVEGTPDWTTTLSVVMGMLVVLVGLSALLLFLQYRRLRKGYTPLMETQLSHKRYTEEA", "output": "Plays a role in melanin biosynthesis. Catalyzes the conversion of L-dopachrome into 5,6-dihydroxyindole-2-carboxylic acid (DHICA)."}]}
+{"id": "function_test_565", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGFMCQGGDFTRHNGTGGKSIYGEKFDDENFILKHTGPGILSMANAGPNTNGSQFFICTVKTEWLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQL", "output": "Catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity). Exerts a strong chemotactic effect on leukocytes partly through activation of one of its membrane receptors BSG/CD147, initiating a signaling cascade that culminates in MAPK/ERK activation (By similarity). Activates endothelial cells (ECs) in a proinflammatory manner by stimulating activation of NF-kappa-B and ERK, JNK and p38 MAP-kinases and by inducing expression of adhesion molecules including SELE and VCAM1 (By similarity). Induces apoptosis in ECs by promoting the FOXO1-dependent expression of CCL2 and BCL2L11 which are involved in EC chemotaxis and apoptosis (By similarity). In response to oxidative stress, initiates proapoptotic and antiapoptotic signaling in ECs via activation of NF-kappa-B and AKT1 and up-regulation of antiapoptotic protein BCL2 (By similarity). Negatively regulates MAP3K5/ASK1 kinase activity, autophosphorylation and oxidative stress-induced apoptosis mediated by MAP3K5/ASK1 (By similarity). Necessary for the assembly of TARDBP in heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and regulates TARDBP binding to RNA UG repeats and TARDBP-dependent expression of HDAC6, ATG7 and VCP which are involved in clearance of protein aggregates (By similarity). Plays an important role in platelet activation and aggregation (By similarity). Regulates calcium mobilization and integrin ITGA2B:ITGB3 bidirectional signaling via increased ROS production as well as by facilitating the interaction between integrin and the cell cytoskeleton (By similarity). Binds heparan sulfate glycosaminoglycans (By similarity)."}]}
+{"id": "function_test_566", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRTLWIMAVCLIGVEGNFFQFAEMIVKMTGKEAVHSYAIYGCYCGWGGQGKPQDATDRCCFVHDCCYGTVNDCNPKMATYSYSFENGDIVCGDNNLCLKTVCECDRAAAICLGQNVNTYDKNYENYAISHCTEESEQC", "output": "Heterodimer (A and B chains): phospholipase A2 that acts as a presynaptic neurotoxin and shows a PLA2 activity of 1377 umol/min/mg. In vivo, induces edema and produces neurotoxic symptoms in mice. Also exhibits indirect hemolysis, a strong myonecrotic activity and cytotoxicity. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.; "}]}
+{"id": "function_test_567", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDKKSRVLIVGGTGYIGKRIVNASISLGHPTYVLFRPEVVSNIDKVQMLLYFKQLGAKLIEASLDDHQRLVDALKQVDVVISALAGGVLSHHILEQLKLVEAIKEAGNIKRFLPSEFGMDPDIMEHALQPGSITFIDKRKVRRAIEAASIPYTYVSSNMFAGYFAGSLAQLDGHMMPPRDKVLIYGDGNVKGIWVDEDDVGTYTIKSIDDPQTLNKTMYIRPPMNILSQKEVIQIWERLSEQNLDKIYISSQDFLADMKDKSYEEKIVRCHLYQIFFRGDLYNFEIGPNAIEATKLYPEVKYVTMDSYLERYV", "output": "Reductase involved in lignan biosynthesis. Catalyzes the enantioselective sequential conversion of (-)-pinoresinol into (-)-lariciresinol and of (-)-lariciresinol into (+)-secoisolariciresinol. Can also convert with a lower efficiency (+)-pinoresinol into (+)-lariciresinol, but not (+)-lariciresinol into (-)-secoisolariciresinol. Abstracts the 4R-hydride from the NADPH cofactor during catalysis."}]}
+{"id": "function_test_568", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEMDMDIIRKAIAATIFALVMAWAWRVLDWAWFTPKRIEKRLRQQGFRGNPYRFLVGDVKESGKMHQEALSNPMEFDNDIVPRLMPHINHTIKTYGRNSFTWMGRIPRIHVMEPELIKEVLTHSSKYQKNFDVHNPLVKFLLTGVGSFEGAKWSKHRRIISPAFTLEKLKSMLPAFAICYHDMLTKWEKLAEKEGSHEVDIFPTFDVLTSDVISKVAFGSTYDEGGKIFRLLKELMDLTIDCMRDVYIPGWSYLPTKRNKRMKEINKEITDMLRFIINKRMKALKAGEPGEDDLLGVLLESNIQEIQKQGNRKDGGMTINDVIEECKLFYFAGQETTGVLLTWTTILLSKHPEWQERAREEVLQAFGKNKPEFERLNHLKYVSMILYEVLRLYPPVIDLTKIIHEDTKLGPYTIPAGTQVMLPTVMLHREKSIWGEDAMEFNPMRFADGVANATKNNVTYLPFSWGPRVCLGQNFALLQAKLGLAMILQRFKFDVAPSYVHAPFTILTVQPQFGSHVIYKKLERQNF", "output": "Component of the seco-iridoid and derivatives monoterpenoid indole alkaloids (MIAs, e.g. secologanin) biosynthesis pathway. Catalyzes the conversion of loganin into secologanin . Catalyzes the conversion of secologanin into secoxyloganin ."}]}
+{"id": "function_test_569", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MALVFRTVAQLAGVSLSLLGWVLSCLTNYLPHWKNLNLDLNEMENWTMGLWQTCVIQEEVGMQCKDFDSFLALPAELRVSRILMFLSNGLGFLGLLVSGFGLDCLRIGESQRDLKRRLLILGGILSWASGVTALVPVSWVAHKTVQEFWDENVPDFVPRWEFGEALFLGWFAGLSLLLGGCLLHCAACSSHAPLASGHYAVAQTQDHHQELETRNTNLKH", "output": "Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity."}]}
+{"id": "function_test_570", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGTDNQTWVSEFILLGLSSDWDTRVSLFVLFLVMYVVTVLGNCLIVLLIRLDSRLHTPMYFFLTNLSLVDVSYATSVVPQLLAHFLAEHKAIPFQSCAAQLFFSLALGGIEFVLLAVMAYDRYVAVCDALRYSAIMHGGLCARLAITSWVSGFISSPVQTAITFQLPMCRNKFIDHISCELLAVVRLACVDTSSNEVTIMVSSIVLLMTPFCLVLLSYIQIISTILKIQSREGRKKAFHTCASHLTVVALCYGVAIFTYIQPHSSPSVLQEKLFSVFYAILTPMLNPMIYSLRNKEVKGAWQKLLWKFSGLTSKLAT", "output": "Odorant receptor."}]}
+{"id": "function_test_571", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAPPQRHPQRSEQVLLLTLLGTLWGAAAAQIRYSIPEELEKGSFVGNIVKDLGLEPQELAEHGVRIVSRGRMQLFSLNPRNGSLVTAGRIDREELCAQSPRCLVSFNILVEDKLNLYPVEVEIVDINDNTPRFLKEELEVKILENAAPSSRFPLMEVYDPDVGMNSLQGFKLSGNSHFSVDVQSEAHGPKYPELVLEGTLDREGEAVYRLVLTAMDGGDPVRSSVAQILVTVLDVNDNTPMFTQPVYRVSVPENLPVGTPVLAVTATDQDEGVHGEVTYSFVKITEKISQIFCLNVLTGEISTSANLDYEDSSFYELGVEARDGPGLRDRAKVLITILDVNDNVPEVVVTSGSRTIAESAPPGTVIALFQVFDRDSGLNGLVTCSIPRSLPFELEKSVGNYYRLVTNAALDREEVFLYNITVTATDKGTPPLSTETIISLNVADTNDNPPTFPHSSYSVYVLENNPRGASIFSVNALDPDVDQNAQVSYSLAEDTLQGAPLSSYVSINSDTGILYALRSFDYEQLRDLQLWVTASDSGDPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADRIPDILADLGSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFVIVLLALRLQRWHKSRLLQASGGGLASMPGSHFVGVEGVRAFLQTYSHEVSLTADSRKSHLIFPQPNYADTLINQESYEKSEPLLITQDLLETKGEPRQLQQAPPNTDWRFSQAQRPGTSGSQNGDDTGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK", "output": "Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain."}]}
+{"id": "function_test_572", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEEQDLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ", "output": "Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain."}]}
+{"id": "function_test_573", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPEAKPAAKKAPKGKDAPKGAPKEAPPKEAPAEAPKEAPPEDQSPTAEEPTGVFLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFSFKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSLESFKRTSEKKSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKKSEYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPDLTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEPPVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSDEKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLNFLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ", "output": "Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role."}]}
+{"id": "function_test_574", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKTPFGKAAAGQRSRTGAGHGSVSVTMIKRKAAHKKHRSRPTSQPRGNIVGCRIQHGWKDGDEPLTQWKGTVLDQVPVNPSLYLIKYDGFDCVYGLELHRDERVSSLEVLPNRVASSRISDTHLAEIMVGKAVEHIFETEEGSKNEWRGMVLAQAPVMNTWFYITYEKDPVLYMYQLLDDYKDGDLRILQDSNDSPLAEREPGEVIDSLVGKQVEYAKDDGSKRTGMVIHQVEAKPSVYFIKFDDDFHIYVYDLVKTS", "output": "Exhibits H3K4me3-binding activity."}]}
+{"id": "function_test_575", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSGEATVLAYHAPEEQEGLLVVKVEEENYVLDQDFGLQENPWSQEVFRQKFRQFSYSDSTGPREALSRLRELCCQWLRPEVHSKEQILELLMLEQFLAILPEELQAWLREHRPENGEEAVTMLEELEKELEEPRQQDTTHGQEMFWQEMTSTGALKSLSLNSPVQPLENQCKTETQESQAFQERDGRMVAGKVLMAKQEIVECVASAAMISPGKLPGETHSQRIAEEALGGLDNSKKQKGNAAGNKISQLPSQDRHFSLATFNRRIPTEHSVLESHESEGSFSMNSNDITQQSVDTREKLYECFDCGKAFCQSSKLIRHQRIHTGERPYACKECGKAFSLSSDLVRHQRIHSGEKPYECCECGKAFRGSSELIRHRRIHTGEKPYECGECGKAFSRSSALIQHKKIHTGDKSYECIACGKAFGRSSILIEHQRIHTGEKPYECNECGKSFNQSSALTQHQRIHTGEKPYECSECRKTFRHRSGLMQHQRTHTRV", "output": "May be involved in transcriptional regulation."}]}
+{"id": "function_test_576", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLSPEAERVLRYLVEVEELAEEVLADKRQIVDLDTKRNQNREGLRALQKDLSLSEDVMVCFGNMFIKMPHPETKEMIEKDQDHLDKEIEKLRKQLKVKVNRLFEAQGKPELKGFNLNPLNQDELKALKVILKG", "output": "May play a role in chaperone-mediated protein folding."}]}
+{"id": "function_test_577", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAPTGLLVAGASFLAFRGLHWGLRRLPTPESAARDRWQWWNLCVSLAHSLLSGTGALLGLSLYPQMAADPIHGHPRWALVLVAVSVGYFLADGADLLWNQTLGKTWDLLCHHLVVVSCLSTAVLSGHYVGFSMVSLLLELNSACLHLRKLLLLSRQAPSLAFSVTSWASLATLALFRLVPLGWMSLWLFRQHHQVPLALVTLGGIGLVTVGIMSIILGIRILVNDVLQSRPHPPSPGHEKTRGTRTRRDNGPVTSNSSTLSLKD", "output": "Regulates the composition and fluidity of the plasma membrane . Inhibits the incorporation of membrane-fluidizing phospholipids containing omega-3 long-chain polyunsaturated fatty acids (LCPUFA) and thereby promotes membrane rigidity . Does not appear to have any effect on LCPUFA synthesis ."}]}
+{"id": "function_test_578", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGPLQFRDVAIEFSLEEWHCLDTAQRNLYRDVMLENYRNLVFLGIVVSKPDLVTCLEQGKKPLTMERHEMIAKPPVMSSHFAQDLWPENIQNSFQIGMLRRYEECRHDNLQLKKGCKSVGEHKVHKGGYNGLNQCLTTTQKEIFQCDKYGKVFHKFSNSNTYKTRHTGINLFKCIICGKAFKRSSTLTTHKKIHTGEKPYRCEECGKAFNQSANLTTHKRIHTGEKPYRCEECGKAFKQSSNLTTHKKIHTGEKPYKCEECGKAFNRSTDLTTHKIVHTGEKPYKCEECGKAFKHPSHVTTHKKIHTRGKPYNCEECGKSFKHCSNLTIHKRIHTGEKPYKCEECGKAFHLSSHLTTHKILHTGEKPYRCRECGKAFNHSTTLFSHEKIHTGEKPYKCDECGKTFTWPSILSKHKRTHTGEKPYKCEECGKSFTASSTLTTHKRIHTGEKPYKCEECGKAFNWSSDLNKHKKIHIERKPYIVKNVTDLLNVPPLLISIR", "output": "May function as a transcription factor. Seem to have a transcriptional repression activity."}]}
+{"id": "function_test_579", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MELDSALEAPSQEDSNLSEELSHSAFGQAFSKILHCLARPEARRGNVKDAVLKDLGDLIEATEFDRLFEGTGARLRGMPETLGQVAKALEKYAAPSKEEEGGGDGHSEAAEKAAQVGLLFLKLLGKVETAKNSLVGPAWQTGLHHLAGPVYIFAITHSLEQPWTTPRSREVAREVLTSLLQVTECGSVAGFLHGENEDEKGRLSVILGLLKPDLYKESWKNNPAIKHVFSWTLQQVTRPWLSQHLERVLPASLVISDDYQTENKILGVHCLHHIVLNVPAADLLQYNRAQVLYHAISNHLYTPEHHLIQAVLLCLLDLFPILEKTLHWKGDGARPTTHCDEVLRLILTHMEPEHRLLLRRTYARNLPAFVNRLGILTVRHLKRLERVIIGYLEVYDGPEEEARLKILETLKLLMQHTWPRVSCRLVVLLKALLKLICDVARDPNLTPESVKSALLQEATDCLILLDRCSQGRVKGLLAKIPQSCEDRKVVNYIRKVQQVSEGAPYNGT", "output": "Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs."}]}
+{"id": "function_test_580", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAGLSGAQIPDGEFTAVVYRLIRNARYAEAVQLLGGELQRSPRSRAGLSLLGYCYYRLQEFALAAECYEQLGQLHPELEQYRLYQAQALYKACLYAEATRVAFLLLDNPAYHSRVLRLQAAIKYSEGDLPGSRSLVEQLPSREGGEESGGENETDGQINLGCLLYKEGQYEAACSKFFAALQASGYQPDLSYNLALAYYSSRQYASALKHIAEIIERGIRQHPELGVGMTTEGIDVRSVGNTLVLHQTALVEAFNLKAAIEYQLRNYEAAQEALTDMPPRAEEELDPVTLHNQALMNMDARPTEGFEKLQFLLQQNPFPPETFGNLLLLYCKYEYFDLAADVLAENAHLIYKFLTPYLYDFLDAVITCQTAPEEAFIKLDGLAGMLTEVLRKLTIQVQEARHNRDDEAIKKAVNEYDETMEKYIPVLMAQAKIYWNLENYPMVEKIFRKSVEFCNDHDVWKLNVAHVLFMQENKYKEAIGFYEPIVKKHYDNILNVSAIVLANLCVSYIMTSQNEEAEELMRKIEKEEEQLSYDDPDKKMYHLCIVNLVIGTLYCAKGNYDFGISRVIKSLEPYNKKLGTDTWYYAKRCFLSLLENMSKHTIMLRDSVIQECVQFLEHCELHGRNIPAVIEQPLEEERMHVGKNTVTYESRQLKALIYEIIGWNI", "output": "Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip."}]}
+{"id": "function_test_581", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRRDVNGVTKSRFEMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL", "output": "Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Role in neural transmission (By similarity)."}]}
+{"id": "function_test_582", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDNQQLPYAGQPAAAGAGAPVPGVPGAGGPPAVPHHHLLQQQQAQLQAFWAYQRQEAERASASDFKNHQLPLARIKKIMKADEDVRMISAEAPVLFAKACELFILELTIRSWLHAEENKRRTLQRNDVAAAIARTDVFDFLVDIVPREEAKEEPGSALGFAAGGPAGAVGAAGPAAGLPYYYPPMGQPAPMMPAWHVPAWDPAWQQGAAPDVDQGAAGSFSEEGQQGFAGHGGAAASFPPAPPSSE", "output": "Probable transcription factor involved in the regulation of flowering time under long day (LD) conditions. Functions as repressor of flowering, independently of HD1 and GHD7. Controls flowering time by negatively regulating the expression of EHD1 and HD3A . Component of the NF-Y/HAP transcription factor complex (By similarity)."}]}
+{"id": "function_test_583", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLKKMLKSYDYSLIFAIVLLCGFGLVMVYSSSMITAVSRYGVSSNFFFMRQLFALIAGGALFILMALFPYKALAHQKFQKGILLVSVLALISLFVFGHVAGNAQSWFKIGGMSIQPGEFVKLVVILYLAAVYAKKQSYIDHLLTGVAPPVVMTLIICGLIAMQPDFGTAMIIGLIATCMILCSGFSGKTLVRLVILGGIVFILVSPIIYLNQDKILTEGRLARFESLEDPFKYANSSGLQVINSYYAISSGGIFGLGLGESIQKYGYLPESHTDFIMAVIAEELGIFGVLFVIFLLGFVVIKGFYIARKCEDPFGSLLAIGISSMIAIQSFINLGGVSGLIPITGVTLPFISYGGSSLVLLLGSMGILANISMFVKYSENKKKKEPLAPKGMKKKQLKKTVYL", "output": "Peptidoglycan polymerase that is essential for cell division."}]}
+{"id": "function_test_584", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTWCNDRSDVQTVERIIPSPGAAESPVASLPVSCHKTCPSCGHNFKFHEQAGIHDLPGLPAGVKFDPTDQEVLEHLEGKVRDDAKKLHPLIDEFIRTIDGENGICYTHPEKLPGVNKDGTVRHFFHRPSKAYTTGTRKRRKVHTDSDVGGETRWHKTGKTRPVLAGGRVRGYKKILVLYTNYGKQKKPEKTNWVMHQYHLGTSEEEKEGELVVSKVFYQTQPRQCGGSVAAAATAKDRPYLHGLGGGGGRHLHYHLHHNNGNGKSNGSGGTAGAGEYYHNIPAIISFNQTGIQNHLVHDSQPFIP", "output": "Transcriptional activator that plays a regulatory role in the development of secondary cell wall fibers . Involved in the regulation of cellulose and hemicellulose biosynthetic genes as well as of genes involved in lignin polymerization and signaling . Is not a direct target of SND1 ."}]}
+{"id": "function_test_585", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSAAVLLSVLFALACGQAASFCIPTEYTMYVDRRECAYCLTINTTICAGYCMTRDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPHHVTPYFSFPVAVSCKCGKCNTDNSDCIHEAVRTNYCTKPQSFYLGGFSV", "output": "Indispensable for the control of thyroid structure and metabolism."}]}
+{"id": "function_test_586", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLLDDQLKYWVLLPISIVMVLTGVLKQYIMTLITGSSANEAQPRVKLTEWQYLQWAQLLIGNGGNLSSDAFAAKKEFLVKDLTEERHLAKAKQQDGSQAGEVPNPFNDPSMSNAMMNMAKGNMASFIPQTIIMWWVNHFFAGFILMQLPFPLTAKFKEMLQTGIICQDLDVRWVSSISWYFISVLGLNPVYNLIGLNDQDMGIQAGIGGPQGPQGPPQSQVDKAMHAMANDLTIIQHETCLDNVEQRVLKQYM", "output": "Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins . Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues . Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices . It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes. By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins (By similarity)."}]}
+{"id": "function_test_587", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAVLIFLGCLLGGIAIGLPIAWALLLCGAALMFWLDMFDVQIMAQTLVNGADSFSLLAIPFFVLAGEIMNAGGLSKRIVDLPMKLVGHKPGGLGYVGVLAAMIMASLSGSAVADTAAVAALLVPMMRSANYPVNRAAGLIASGGIIAPIIPPSIPFIIFGVSSGLSISKLFMAGIAPGMMMGATLMLTWWWQASRLNLPRQQKATMQEIWHSFVSGIWALFLPVIIIGGFRSGLFTPTEAGAVAAFYALFVATVIYREMTFATLWHVLIGAAKTTSVVMFLVASAQVSAWLITIAELPMMVSDLLQPLVDSPRLLFIVIMVAILIVGMVMDLTPTVLILTPVLMPLVKEAGIDPIYFGVMFIINCSIGLITPPIGNVLNVISGVAKLKFDDAVRGVFPYVLVLYSLLVVFVFIPDLIILPLKWIN", "output": "Part of the tripartite ATP-independent periplasmic (TRAP) transport system YiaMNO involved in the uptake of 2,3-diketo-L-gulonate."}]}
+{"id": "function_test_588", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGEMEQLKQEAEQLKKQIADARKACADITLAELVSGLEVVGRVQMRTRRTLRGHLAKIYAMHWATDSKLLVSASQDGKLIVWDTYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNMCSIYSLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTTCALWDIETGQQKTVFVGHTGDCMSLAVSPDYKLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAICTGSDDASCRLFDLRADQELTAYSHESIICGITSVAFSLSGRLLFAGYDDFNCNVWDSLKCERVGVLSGHDNRVSCLGVTADGMAVATGSWDSFLKIWN", "output": "Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction."}]}
+{"id": "function_test_589", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSASVVSVISRFLEEYLSSTPQRLKLLDAYLLYILLTGALQFGYCLLVGTFPFNSFLSGFISCVGSFILAVCLRIQINPQNKADFQGISPERAFADFLFASTILHLVVMNFVG", "output": "Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (By similarity). N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity."}]}
+{"id": "function_test_590", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKFGKTFANHRIPEWSSQYVGYKSLKKMIKEITRLQEDIYRAHNKNSYDEGRPPTKMRDSSNSAQNYLDSPKIQKLLASFFFAVDRDIEKVDTFYNSQYAEYKKRFERLLSSNQFNEIKSTLVVDANKEDAVAQTLLTKDTREMNMLLKGTSQASRLSYHKDDLIEIQSILAELRKQFRNLKWYAELNKRAFGKILKKLDKKVGTNQQMSTMKTRILPLQFANDSLITKDLSLLKTIWEQVTFRINSYERVMRSTSPNANANDNTEFFKIICVFIEEDDSKGLIRELTNLYSELSLIPTRIMISVLNKAALSKSLACIDAILKVIPSLNDSEDINRRNFFHHHIIAIGKLIRKQEILSRKKKSQPSKYTNSEGEIVTDLRTLHTTLSAPAESDSITEEEKSSACTLSYILEELPIHLRPCLFQHDNYKRTPLHYSCQYGLSEVTKLIIKLMKEWNIWNEIPIDDVSAFGDAESLTPLHLCVLGAHPKTTEVLLQSLDPNVKLKSSSLLHLATEWNNYPLLHVLLSSKRFDINYQDNELHETPLYLACRLNFFEAAVCLLYNGADLEIREKLFGWTAIFVAAAEGFTDIVKLLIANNANFDIEDEGGWTPMEHAVLRGHLHIADMVQIRDELVTHPHSQLNSGSEEKEPLNEISAGELNERNENGNGGNKGSLGKLAGPIKSYGHRFLDNNESLILITLGSNDTRNKSPSISLSSEALAKVIGLETDCALSLVISCNDSIDKSSVILDLPLDDNVDAVDFKVPFKVDYSHTLYFDIVPTYGTRSLETHNRIDCQKNNNNYVMARGVSMLNKSYSSVGVNRSILNGSVTVPIIANHTLEILGTLKFEYIIITPFEHPQLPLERTETYWKSLVSTRVIGHRGLGKNNPNKSLQIGENTVESFIMAASLGASYVEFDVQLTKDNVPVVYHDFLVAETGVDIPMHELTLEQFLDLNNADKEHIQRGAGHSPHHVNGADTALQKYRGRSVDDSDVSTLRRAWDLHDNDPNGKSNNAHWSDNRMRLTKTFKKNNFKGNARGHSIASSFVTLKELFKKIPANVGFNIECKFPMLDEAEEEELGQIMMEMNHWVDTVLKVVFDNANGRDIIFSSFHPDICIMLSLKQPVIPILFLTEGGSEQMADLRASSLQNGIRFAKKWNLLGIVSAAAPILKAPRLVQVVKSNGLVCVTYGVDNNDPENASIQIEAGVDAVIVDSVLAIRRGLTKKNEK", "output": "Glycerophosphocholine glycerophosphodiesterase responsible for the hydrolysis of intracellular glycerophosphocholine into glycerol-phosphate and choline . The choline is used for phosphatidyl-choline synthesis. Required for utilization of glycerophosphocholine as phosphate source . May also use glycerophosphoinositol as substrate in vivo ."}]}
+{"id": "function_test_591", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSSVNQIYDLFPNKHNIQFTDSHSQEHDTSSSLAKNDTDGTISIPGSIDTGILKSIIEEQGWNDAELYRSSIQNQRFFLTDKYTKKKHLTMEDMLSPEEEQIYQEPIQDFQTYNKRVQREYELRERMEEFFRQNTKNDLHILNEDSLNQQYSPLGPADYVLPLDRYSRMKHIASNFFRKKLGIPRKLKRRSHYNPNAEGHTKGNSSILSSTTDVIDNASYRNIAIDENVDITHKEHAIDEINEQGASGSESVVEGGSLLHDIEKVFNRSRATRKYHIQRKLKVRHIQMLSIGACFSVGLFLTSGKAFSIAGPFGTLLGFGLTGSIILATMLSFTELSTLIPVSSGFSGLASRFVEDAFGFALGWTYWISCMLALPAQVSSSTFYLSYYNNVNISKGVTAGFITLFSAFSIVVNLLDVSIMGEIVYVAGISKVIIAILMVFTMIILNAGHGNDIHEGVGFRYWDSSKSVRNLTYGLYRPTFDLADAGEGSKKGISGPKGRFLATASVMLISTFAFSGVEMTFLASGEAINPRKTIPSATKRTFSIVLISYVFLIFSVGINIYSGDPRLLSYFPGISEKRYEAIIKGTGMDWRLRTNCRGGIDYRQISVGTGYSSPWVVALQNFGLCTFASAFNAILIFFTATAGISSLFSCSRTLYAMSVQRKAPPVFEICSKRGVPYVSVIFSSLFSVIAYIAVDQTAIENFDVLANVSSASTSIIWMGLNLSFLRFYYALKQRKDIISRNDSSYPYKSPFQPYLAIYGLVGCSLFVIFMGYPNFIHHFWSTKAFFSAYGGLMFFFISYTAYKVLGTSKIQRLDQLDMDSGRREMDRTDWTEHSQYLGTYRERAKKLVTWLI", "output": "Amino acid sensor component of the SPS-sensor system, which regulates the expression of several amino acid-metabolizing enzymes and amino acid- and peptide-permeases in response to extracellular amino acid levels by controlling the activity of two transcription factors, STP1 and STP2. Amino-acid permease homolog that seems to interact directly with the extracellular signaling molecules, but has no amino acid transporter activity. May recruit casein kinases YCK1 and YCK2 to hyperphosphorylate and activate downstream component PTR3 in response to amino acid stimulus."}]}
+{"id": "function_test_592", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAATLVAARGTRPAPAWGPEAIAPDWENREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQPFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAAIAEPGVERQVLLGDQIPKFTIATLPPL", "output": "Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB6 displays a peptidylglutamyl-hydrolyzing activity also termed postacidic or caspase-like activity, meaning that the peptides bond hydrolysis occurs directly after acidic residues."}]}
+{"id": "function_test_593", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDPEEQELLNDYRYRSYSSVIEKALRNFESSSEWADLISSLGKLNKALQSNLKYSLLPRRLIISKRLAQCLHPALPSGVHLKALETYEIIFKIVGTKWLAKDLFLYSCGLFPLLAYAAMSVRPVLLGLYEKYFLPLQKLLLPSLQAFLVGLLPGLEEGSEIYERTDALLLRLSVVVGREVFYAALWGSVLTSPSIRLPASLFVVNHISRDSPGKEQKCMLGTDYQLTVRSLCASLLDANVLVQRNNLEIILFFFPFYTCLDPEERAIPLLRRDVVHILSAATQTLLRRDMSLNRRLYAWLLGSDIKGNTIVPKSEISNSYEDQCSYFFDKYSKDLLVEALAEILHQKFLDADLEERHHAYLKPFRILVSLLDKPEIGPQVVENLFLEVIRAFYSYCHDVLGSDLKLSYTQSGNPLISTIKENRHASEIVKTVNLLVSSLSSDFLWDYMARRFEACFRPVTQTTAIGEAISPPPTVSELCTLLVFLLDVIPLELYSEVQTQYLPQVLGCLLQPLAEEVEALSLPELTHALKTCFKVLSKVQMPPSYLDLEPSSGNSSPVKGRNSGIAMETEAVVAGDEEPSFPPLKSEDSGIGLSASSPELSEHLRVPRVSAERDDIWKKDGTMQATFLCIQELIANFASKNIFAASLTVSGEENKPEEPPGKGNKGQTQSTEHPGRKSSWDPKPITVPQFKQMLSDLFTVRGSPFKTRSSESLSSVPSSPHRKAATEWGVDQVVVELVGSKEDCREALAAACHLLLDCATFPVYLSEEETEQLCETLFQTPGASDCSFPPWLKSLMTICCCVSDCSLQNIAIATLLEVINHSQSLALVIEDKMKRYKTSGNNPFFGKLQMVTVPPIAPGILKVIAEKTDFYQRVARVLWNQLNKETREHHITCVELFYRLHCLAPTANICEDIICHALLDPDKGTRLEALFRFSVIWHLTREIQGSRVTSHNRSFDRSLFVVLDSLACTDGAISAAAQGWLVRALSLGDVARILEPMLLLLLQPKTQRTSIQCLKQENSAEDLHRWFNRKKPTCKEACGESEPQEGAPEERLPRGQFTTVDREAIWAEVEKEPEKCPPRSDLSEEDLPYYVDLPDRMTSGGGDSSEHTESADTSSGHTDSENTSTFSSPSHDLQDLSHEENCCAPIPIGGRAYSKRAALLAAFQPESPRSNARLSLVRADSDKTQASESFSSDEEADVELQAITTSRLLKQQREKQETVEALFKHILLYLQPYDSQRVLYAFSVLEAVLKTNPKEFIEAVSRTGIDTSSTAHLNLISNLLARHQEALIGQSFYGKLQTQAPNVCPHSLLIELLTYLCLSFLRSYYPCYLKVCHRDILGNRDVQVKSVEVLIRITAQLVSMAKSAEGKNTEFIHSLLQRCKVQEFVLLSLSASMYTSQKRYGLATADRGGRLLAEDSLFEESLINLGQDQIWSEHPLQIELLKLLQALIVLEHHLGQGQEEAETQPALSREWQRALNFQQAIGAMQYVQPHPLTSQGLLVSAVVRGLQPAYGYGMHPAWVSLVTHSLPYFGKSLGWTVTPFVIQICKNLDDLVKQYESESVKFTISTTSKKENISPDYPLTLLEGLTTISHFCLLEQPTQHKKTAAVSDPINLRNAKNAILEELPRIVNTMALIWNVLRKEETQKRPVDLLGATKGSSSVYFKTTKTIRQKILDLLNPLTGHLGVQLIAAVATVWNRKQARRHSKTKMVPVANTSQHTLVDLVCALSTLQTDSVLQLVKEVVKRPAQIKGDEKSPLVDIPVLQFCYAFIQRLSIPDLQEAFPSLLGVLKEAAQLNLAPPGYFLLLSMLNDFVTRTPNLESKKDQKDLQEITQRILEAVGTIAGSSLEQTSWLSRNLEVKAQPQVSLEESDAEDDVHSAAEASTMVSASAPSVYSVQALSLLAEVLASLLDMVYRSDEKEKAVPLISRLLYYVFPYLRNHSAYNAPSFRAGAQLLSSLSGYAYTKRAWKKEVLELFLDPAFFQMDTSCVHWKSVIDHLLTHEKTMFKDLMNMQSSSLKLFSSFEQKAMLLKRQAFAVFSGELDQYHLYLPLIQERLTDNLRVGQTSIVAGQMFLFFRVLLLRISPQHLTSLWPIMVSELIQTFIQLEEDLKEEDESRNSHKSNRIKAPVADGNGSAGRVLSPSDLTMYLSACKFLDTALAFPPDKMPLFQIYRWAFVPEVDTEHPAFLSELEENHQECRPHTVRILELLRSRYGEIGSSDEITRKKEFPLLRQHSVSCIRQLIPFFTTLNCAFKTQSQLPADVPGTAAPECPVTENPRVLRQLEECVEQDFLEHPEC", "output": "May play a role in regulating membrane trafficking of cargo proteins. Together with ATP9A and MON2, regulates SNX3 retromer-mediated endosomal sorting of WLS away from lysosomal degradation."}]}
+{"id": "function_test_594", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRECLSIHIGQAGVQIGDACWELYCLEHGIQPDGFILDHQHDNLENPKVEHMNASLDTFFHETRAGKHVPRTLFMDLEPTVIDGIRVGRYHSLFHPEQLVNGKEDAANTYARGRYSVGSEVIELVLERIRKLAEQCSGLQGFLIYRSFGGGTGSGFTSLLMERLSVEYCKKIKLEFSVYPSPRISTAVVEPYNAILTTHSTIEYSDCAFMVDNEALYDICQHKLGIERPSYASINRLIAQVSSSITASLRFEGPLNVDLIEFQTNLVPYPRIHFPITALAPIISAEKAYQEQLSVSDVTASCFEVSNQLVKCDPRLGKYMACCLLYRGDVVPKDVNEAIAAMKSRTSVQFVDWCPTGFKVGINYQPPAVVPGGDLARVQRAVCMLSNTTAIVEAWARLDHKFDLMYAKKAFLHWYITEGMELGEFVEAREDLAALEKDYEEVGLSF", "output": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin."}]}
+{"id": "function_test_595", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKAGRGTLGVCLAKQSQGGDPDKLACGLKKRSQKRNPSPSVVPSWTDQPVADSHGKSRATGAAASEMKHGQSKASLLHHGGFKVLQSLKGSVGRSSAPAASLGKAVALSPAPSEEQLAGMSHGIGDALGSDWPGREPRATDNRGQYLKGESWVSGRPGHPKLREVGFLRGEPPSAGPKGLGTWSELSHRYFELGQLPYAYPYYKVLPEGELRCVSLDRFNPGLSEETVEDEKTLKFFRWSADSRGVTGSAIFQISKSLMP", "output": "May negatively regulate STAT3."}]}
+{"id": "function_test_596", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTHTRRKSLPMLSSGPTGRGEPLQMEDSNMEQGTEDVEPGMPESPGHLTGRRKNYPLRKRSLVPEKPKACKVLLTRLENVAGPRSADEADELPPDLPKPPSPTSSSEDAGLVQPRKRRLASLNAEALNNLLLEREETSSLAGARRSRGGDPHRSRDRATGSWSFSKKRPRLGDLGEGSRDLSPELAPDEGARRDGDPAPKRLASLNAAAFLKLSQERELPLRPSRAQAEADGRSTEPLAPRILRPKVNGKNCPKARQGAGSGEATGPPNWQEQPDERWPSAPPHGPPTQPSHQAPGKALENPLRPNLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPAPQLSPLPMPGNPADYSGPCGGPELTALGSFYLYCGQDGLQCGAYSPCPMLPEGKLSPVAAPNEGLLMAPSSVPSGVPFQHPPWSAPRYCSSEDTGANGYSICGVLPLSLTHIGTTCGGCPYKMPFTAEGCRSLGQLEFPLPEAGHPASPAHPLLGCPVPSVPPAAEPIPHLQTPISEPQTVARACPQSAKPPSGSKSGLRTGSSCRHTVRSKAARRPSHPKQPRAQRPRPRRRRRRRTNGWVPVGAACEKAVYVLDEPEPAIRKSYQAVERHGETIRVRDTVLLKSGPRKTSTPYVAKISALWENPESGELMMSLLWYYRPEHLQGGRSPSMHEPLQNEVFASRHQDQNSVACIEEKCYVLTFAEYCRFCAMAKRRGEGLPSRKTALVPPSADYSTPPHRTVPEDTDPELVFLCRHVYDFRHGRILKNPQ", "output": "Heterochromatin protein that acts as a transcription repressor and has the ability to promote the formation of large heterochromatic domains. May act by recruiting heterochromatin proteins such as CBX5 (HP1 alpha), HDAC5 and MBD1. Represses IGF2 expression by binding to its CpG-rich P3 promoter and recruiting heterochromatin proteins (By similarity)."}]}
+{"id": "function_test_597", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLRNTVKRLMTYTFKPSKQTSSFGPSVWLEFSPLAIKYNAVNLGQGFPNFEPPKFVKDAMIKTIEVGGFNQYTRSPGHIRLVKALSSVYSPYFGRELNAMTEIMVGVGASESLFAAISSIVNEGDEVILIEPFFDIYIGPILMAGGIPKFVTLKEEESSQAGSSDKKRSSKHWKINKEELAAAFTDKTKLIILNNPHNPVGKVYSKEELQEIADVVAKHGPNTTVISDEVYEWMTFDGEEHHRFATLPGMWERTITIGSAGKTFSITGWKVGWCIGPSNIIGAIANTHQYVPFSVPTPTQEAVAIALEQPNIKDYFKELATMYQNKRDTLLNSLTQAGLDPVIPQGTYFIMGDTSSIHLQGDQGKDTSITGMGLHLRDWNIARYLTTEYGVTTIPPSAFYCDDHQKIPENFVRFTFCKDDLTLQKAHDNLLKLKK", "output": "Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond (By similarity)."}]}
+{"id": "function_test_598", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAGVFSYESSEVDWCEDNYKHSENVVEYFNTMSSFIFFVISPIMLYLLHPYAKERNLAVHLVWIMMVFVGIFSMYFHMTLSFMGQMLDELSILWVLAIGYSLWFPRKHFPSFVKDRTSFARLVLTITIISTLSSFVKPTANAYALNCFAIHILYSLFVELKSCTDERVLRLAWASIGLWVLAISCWISDRFGCSFWQKLDFCYLHGIWHILIVMATAYASTLIAYLDASQEIPYSLPDLQYWPRNNWAIGLPYIVLKGTNTTRKTC", "output": "Endoplasmic reticulum ceramidase that catalyzes the hydrolysis of ceramides into sphingosine and free fatty acids at alkaline pH. Ceramides, sphingosine, and its phosphorylated form sphingosine-1-phosphate are bioactive lipids that mediate cellular signaling pathways regulating several biological processes including cell proliferation, apoptosis and differentiation. May also hydrolyze dihydroceramides to produce dihydrosphingosine."}]}
+{"id": "function_test_599", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAVAPPLPPAPARQLRRWKGSSPRPPPWLSSPFRRTRYLSRPAFAAGGRQDYSPSSGMGVSKTGAFRLGLYGNLNVQSSVQEWVDETKRLFFLRTTNSVRNNITNGTTPLRVGNLRHDPSEDIRSSNYPSLYNQRERGPSNSIVNRHVDTDLAKHRVMYQSAHAVPAPFSVVNNDIKPLNMLDGSKEEIPWHDSVTMESSLPKVSKSEKTLVVDKAIPDKKEHKRITRKVTPNFPDKASLSTESKNARKLLATIYDKVLVVDNVESARSVVKLLTTKYKGFIHACDTEVANIDVKEETPVGHGEVICFSICSGNSDGEADFGNGKTCIWVDVLDGGRDVLMEFAPFFEDPFIKKVWHNYSFDIHVIENCGIKVAGFHADTMHLARLWDSSRRTDGGYSLEGLTNDYRVMDAVLKDIPKTGKVSMKTIFGRKKVRKDGSEGKTISIEPVEKLQREDRELWICYSSLDSMSTLKLYESLKNKLEAKEWIFDDCPRGTMYDFYEEYWRPFGALLVKMETEGVLVDRAYLSEIEKAAVTERELAADKFRKWASKHCPDAKYMNVNSDNQIRQLFFGGIENRNKRGETWPQSKTFKVPNDEGIATEGKKTPKSRTIKLFTIVEDLKIDMFTPTGWPSVSGDVLRSLAGKIPTDHIYKIDDGQEFDEDGSSLELPEQDIEDTSPYGTAYEAFGGGKKGREACHAIAALCEVFSIDKLISGFIVPLQGDRISCKEGRIHCSLNINTETGRLSARTPNLQNQPALEKDRYKIRHAFVAAPGNTLIVADYGQLELRILAHLTNCKSMLEAFKAGGDFHSRTAMNMYQHVRDAVEEKKVLLEWHPQPGQDKPPVPLLKDAFGAERRKAKMLNFSIAYGKTAVGLSWDWKVSVREARDTLKLWYRDRKEVSAWQKKQKAFALEKCEVYTLLGRSRQFPNMTHAGPGQKGHVERAAINAPVQGSAADVAMCAMLEIERNARLKELGWRLLLQVHDEVILEGPTESAEEAKTIVVECMSKPFYGTNILKVDLAVDAKYAKSWYAAK", "output": "In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity (By similarity). May be required for DNA replication and accumulation in plastids."}]}
+{"id": "function_test_600", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLAVALLVLLCASASANSIQSRTSSYSGEYGGKGGKRFSHSGNQLDGPITAFRIRVNRYYIVGLQVRYGTVWSDYVGGTQGDLEEIFLHPGESVIQVSGKYKSYVKQMIFVTDKGRYLPFGKASGTSFNAVPLHPNTVLRFISGRSGSAIDSISLHWDTYPSHCNTC", "output": "May play a role in protein trafficking. May act as a linker molecule between the submembranous matrix on the luminal side of zymogen granule membrane (ZGM) and aggregated secretory proteins during granule formation in the TGN (By similarity)."}]}
+{"id": "function_test_601", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MASPQSTKTGLNLPAGMNQTSLRLETFSSSFRGISSLSSPSKSTCSDRFIPCRSSSRLHAFDLQDKEPTTPVKEGGNEAYSRLLKSELFGSDFASPLLSPAGGQGSASSPMSPCTNMLRFKTDRSNSSPSSPFSPSILGNDNGHSSDSSPPPKPPRKVPKTPHKVLDAPSLQDDFYLNVVDWSSQNVLAVGLGTCVYLWTASNSKVTKLCDLGPNDSVCSVQWTREGSYISIGTSHGQVQVWDGTQCKRVRTMGGHQTRTGVLAWNSRILSSGSRDRNILQHDIRVQSDFVSKLVGHKSEVCGLKWSHDDRELASGGNDNQLLVWNNHSQQPILKLTEHTAAVKAITWSPHQSSLLASGGGTADRCIRFWNTTNGNQLNSIDTGSQVCNLAWSKNVNEIVSTHGYSQNQIMLWKYPSMSKVATLTGHSMRVLYLATSPDGQTIVTGAGDETLRFWNVFPSVKMQTPVKDTGLWSLGRTQIR", "output": "Activator protein that regulates the ubiquitin ligase activity and substrate specificity of the anaphase promoting complex/cyclosome (APC/C)."}]}
+{"id": "function_test_602", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSTTTGPEAAPKPSAKSIYEQRKRYSTVVMADVSQYHVNHLVTFCLGEEDGVHTVEDASRKLAVMDSQGRVWAQEMLLRVSPSQVTLLDPVSKEELESYPLDAIVRCDAVMPRGRSRSLLLLVCQEPERAQPDVHFFQGLLLGAELIREDIQGALQNYRSGRGERRAAALRATQEELRRGASPAAETPPLQRRPSVRLVINTVEPSAVRGRPQVESIPETEEARKPDQARTTSSADPTSPDLGPRGPELAGLQAERDVDILNHVFDDVESFVSRLQKSAEATRVLEHRERGRRTRRRAAGEGLLTLRAKPPTEAEYTDVLQKIKYAFSLLARLRGNIANPSSPELLHFLFGPLQMIVNTSGGPEFAKSVRRPHLTLEAVTLLRDNVTPGENELWTSLGDSWTCPGVELPPEEGSPYSPEFYNGWEPPATDPQGRPWEDPVEKQLQHEKRRRQQSAPQVAVNGQQDPELETESQLEEKARKWVLCNYDFQARNGSELSVKHRDVLEVLDDRRKWWKVRDHQGQEGYVPYNILTPHPGPQVHRSQSPARHLETSTPPPPPAPAPAPTQVRPQWDSCDSLNSLDPSEKEKFSQMLCVNEELQSRLAQGRSGPSRVTPGPRAQEPQLSPRSEASVVRAWLQTKGFSSGTVEALGVLTGAQLFSLQKEELRAVCPEEGARVYSQVTVQRALLEDREKVSELEAVMEKQKKKVEGETKTEVI", "output": "Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton (By similarity)."}]}
+{"id": "function_test_603", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEMKKIACGVLFAAASMTAVMAAEEVGAPAPGPASAASAALPALGSLVGASLVSLFSYYLH", "output": "Proteoglycan that seems to be implicated in diverse developmental roles such as differentiation, cell-cell recognition, embryogenesis and programmed cell death."}]}
+{"id": "function_test_604", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MMTPGGSGRLRPLPTAMYAGYSGTASSWVAKTSVSASGKRIQREMAELNIDPPPDCSAGPKGDNLYHWIATIIGPSGTPYEGGIFFLDIIFPSDYPFKPPKLVFKTRIYHCNVDTAGDLSVNILRDSWSPALTITKVLQAIRSIFLKPEPYSPALPVIARLYLTDREKHDEVAKEWTLRFAK", "output": "Component of light signal transduction machinery. Involved in repression of photomorphogenesis in darkness by participating in the CDD complex, a complex probably required to regulate the activity of ubiquitin conjugating enzymes (E2s). Repression of photomorphogenesis is probably mediated by ubiquitination and subsequent degradation of photomorphogenesis-promoting factors such as HY5, HYH and LAF1. Although strongly related to ubiquitin-conjugating enzyme, it has no catalytic activity by itself due to the absence of the conserved Cys active site at position 120. It can however enhance the activity of E2 conjugating enzymes."}]}
+{"id": "function_test_605", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MMPKRFNTSGFDTTLRLPSYYGFLHLTQSLTLNSRVFYGARHVTPPAIRIGSNPVQSLLLFRAPTQLTGWNRSSRDLLGRRVSFSDRSDGVDLLSSSPILSTNPNLDDSLTVIALPLPHKPLIPGFYMPIHVKDPKVLAALQESTRQQSPYVGAFLLKDCASTDSSSRSETEDNVVEKFKVKGKPKKKRRKELLNRIHQVGTLAQISSIQGEQVILVGRRRLIIEEMVSEDPLTVRVDHLKDKPYDKDNAVIKASYVEVISTLREVLKTNSLWRDQDIGDFSYQHLADFGAGISGANKHKNQGVLTELDVHKRLELTLELVKKQVEINKIKETDDGSSLSAKIRVRIDTKRDKIPKHVIKVMEEEFTKLEMLEENYSDFDLTYNYLHWLTVLPWGNFSYENFDVLRAKKILDEDHYGLSDVKERILEFIAVGRLRGTSQGKIICLSGPPGVGKTSIGRSIARALDRKFFRFSVGGLSDVAEIKGHCQTYVGAMPGKMVQCLKSVGTANPLILFDEIDKLGRCHTGDPASALLEVMDPEQNAKFLDHFLNVTIDLSKVLFVCTANVIEMIPGPLLDRMEVIDLSGYVTDEKMHIARDYLVKKTCRDCGIKPEHVDLSDAALLSLIENYCREAGVRNLQKQIEKIYRKVALELVRQGAVSFDVTDTKDTKSLAKTDSEVKRMKVADIMKILESATGDSTESKTKQSGLVAKTFEKVMIDESNLADYVGKPVFQEEKIYEQTPVGVVMGLAWTSMGGSTLYIETTFVEEGLGKGGLHITGQLGDVMKESAQIAHTVARRIMFEKEPENLFFANSKLHLHVPEGATPKDGPSAGCTMITSFLSLAMKKLVRKDLAMTGEVTLTGRILPIGGVKEKTIAARRSQIKTIIFPEANRRDFEELAENMKEGLDVHFVDEYEKIFDLAFNYDH", "output": "ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner."}]}
+{"id": "function_test_606", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAIVSSARESLSHAMNNRFLPNLEYLLQGSILDSAVEHLMHRLKGLCDNVDTSPEPFHDLEVCMSLRQPNANQPLLLRVRRALGRDAPFQMRYLGNPEVDLRRPTLVRSCMDCACTNGILEFLTEMGFRLEFEYIAKGYMFRKGRMKITVSKLIKIVPGKQQDMANEPISQSYIVELSVVAPTGQENVGEEMRVFAEQLKPLVQLEKIDYKRLGGMP", "output": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors."}]}
+{"id": "function_test_607", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MASSNPPPQPAIGAPLAPSAPGPSPEVEEDSGEAFEFDDSDEEEDTSSGLVVPGLAPERDTEPSLICFDTVPGSDLDPAAAPPQTEAPTVVSNGDAVGAAISGVRRSSWKRKSSRRIDRFTFPALEEDVIYDDVPCESPDAHQPGAERGLVYEDVHRAGAPRETEDLGWSSSEFESYSEDSGEETKPEAEPTKHRGSFQPKLSPDLTRLKERYVRTKRDILALRVGGRDMQELKLKCDCKMTQLMKAAKSGTRDGLEKTRMAVMRKVSFLHRKDVLGDSEEEDMGLLEVGVTDIKPPAPELGPMPDGLSPQQVVRRHILGSIVQSEGSYVESLKRILQDYRNPLMEMEPKALSARKCQVVFFRVKEILHCHSMFQIALSSRVAEWDSTEKIGDLFVASFSKSMVLDVYSDYVNNFTNAMSIIKKACLTKPAFLEFLKRRQVCSTDRVTLYGLMVKPVQRFPQFILLLQDMLKNTPRGHPDRLSLQLALTELETLAEKLNEQKRLADQVAEIQQLTKSVSDRSSLNKLLTSGQRQLLLCETLTETVYGDRGQLIKSKERRVFLLNDMLVCANINFKPSNHRGQLEISSLVPLGPKYVVKWNTALPQVQVVEVGQDGGTYDKDNLLIQHAGAKKATAAGQAQNKVYLGPPRLFQELQDLQKDLAVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRLMRVKEEEIHSANKCRLRLLLPGKPDKSGRPISFMVVFITPNPLSKISWVNRLHLAKIGLREENQPGWLCPDEDKKSKAPFWCPILACCVPAFSSRTLSLQLGGLVHSPVNSPLLGFSAVSTSLPQGYLWVGGGQEGAGGQVEIFSLNRPSPRTVKSFPVAAPVLCIEYIPDPEEEAEGAEESRAATDPSVTVHPTVCLGLQDGSILLYGSVDTGTQCLATCKSPGPQPVLCLRHSPFYLLAGLQDGTLAAYPRTSGDIPWDLESPPMCITVGPGPIRTLLSLEDAAWASCGPRVTVLDAATLQTQQSFEAHQDEAVSVTHMVKAGSGVWMAFSSGSSIRLFHTETLEHLQEINIATRTTFLLPGQKHLCVTSLLICQGLLWVGTDQGVIVLLPVPRLEGIPKITGKGMVSLNGHCGPVAFLAVAMSILAPDILRSDQEEAEGPQAEEDKPDGQAHETVPGPDSHTARELTRKKGILLQYRLRSTAHLPGPLLSVREPAPADGSALEHSEEDGSIYEMADDPDVWVRSRPCARDAHRKEICSVAIISGGQGYRHFGGAPGGLSGRAAPCSETDSTLLIWQVPLAL", "output": "Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC."}]}
+{"id": "function_test_608", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSYPFGKEETTTEKQLFEFFCECLRRGDWELAQACVPQLQRGQGEIPQKVEDILQALVQCPILLRCGPDINPQRLAWLWLLVLEKWLPPEKKLLSTVFRRKLEFLFLSEDLQGGIPETILKELFETLAQGPAGCTSDRSQRWESGAPQLSPEAVSMLWNLLKQAPGPAQALLELLLEERHSASLCHSSLQKSLLDLIRKALQTLRDPASQPAGVTDAVCGALQALCCTAELPEGEWHVLCEELLETCRTEGSPLKEERLLGCLLHKAGRSLLSLYGHTYAEKVAERPPKASLSGKDHPDPERAMLALFSTPDPAHAWKMAFFYCLSNNKHFLEQILVTALTLLKEEDFPSLGYLLDREFRPLSHLLVLLGWTHCQSLESAKRLLQTLYRNQDQGHDELLRDACEGLWAHLEVLEWCVQQSSSLIPKRELLCHLHGGDSHSVLYSLHHLTNLPALREEEVLKLLQKVPTKDLQGEHDTHDASVPEHLSQCQSLTLYQGFCAMKYAVYALCVNSHQHSQCPDCRDSASSEELALVEPGRDSLPSPGASHLFPTYLARCRQYLQRIPDSLCLEILENIFSLLLITSADLHPEPHLPEDYAEDDDIEGKGPWGLWSPSESPQHIAATERRSERASMGPRDLAPTGPGCPKGEPKDNSPGPHTHSFLDLKHFTSSLSGFLADEFAIGAFLSLIQEQLNELSSHRTPEETELLEDQSCWAARDGLQGRLHRFSKVLSEAQWRYKVVTSNQSSEEQPSRRYRPTAKRHSSLRRGRRTRRTRADGRERGSNPSLEGTSSELSTSTSEGSLSAVSGQVEADNRFQPQPQSSIIPMMFSPPESLLASCILRGNFAEAHQVVLMFNLKSSPSAGELMFVERYQEVIQELARVEHKIENQNSDGGNNTVRRTGSGRSTLQAIGSAAAAGMVFYSISDVTDKLLSPSEDPIPTLQEDFWINAALTETNTPLRGVLEDLSPPAMAAFDLACCQCQLWKTCKQLLETAERRLSSSLEGRGRRLDQVVLNPDGMRGFPFVLQQISKILSYPLTVTGLTKSETLEERGGGAPRCSISELLQMCWPSLTEDCIASHTSLSQQLDQALQSLREALTLSEPKSTPLTCLVEQAAQKAPEAEAHPVHIQSQLLQKTLGKQTLAGPRQTDYVGAFFSYCSSLAKVLLRSLSSDPDNVEVKVGNPFVLLQQSSSQLVSHLLLERQVPPDRLAALLAQEHLNLSVPQVIVSCCCEPLTLCLSRQSQQASSLTAHLGMLAQGHASHLLDGLPLSVLGSPRPSENPSAERKSDSSPKDSLPAFTASALAFLKSRSKILAMVACLRASRGTKVSRPSLSWKELRGRREAPLTAEKVAQECEHLLEQFPVFEAALLANWEPLQQASESRPSLAASLCGQARLSTVLLGLHSTLAQDVVTEAFEEALVARDWPRALQLIDVYGQDSDDLSSVRDSVLTCATVCDKEGWQYLFPVKDASLRSQLALRFVDKWPLESCLEILAYCVSDMAVPEELKSELQRKLTELRVYQKILGLQDPPVWCDWQTLRSCCAEDPSTVMDMMLGSQEYELCEEWGCLYPIPREHLVSLHHKHLLYLLERREYEKALQLLQRIPDPTMCLEVTERSLDQHPSLATSHFLANYLTSHFYGELTTDRHHEIQALYMGSKVLLTLPEQHRASYAHLSSSPLLMLEQLLMNMKVDWATTAVQTLQQLLAGQDIGFTLDEVDSLLSRYAGKALDLPYPLREKRSDSMIHLQEPVHQASDPETLSRSSSAEFSAAAAAPAPAAPGSALVCSPSPKERAFPQTQPPLEFVPPETPPARDQWVPDETESMCMVCCREHFTMFNRRHHCRRCGRLVCGSCSTKKMVVEGCRENPTRVCDQCYSYYNKDAPEESPCQSEVPDSAKNESPSYSAVVRIPKATEVEWILSLNEEENELVRSEFYYEQAPSASLCIAILNLHRDSIACGHQLIEHCCRLSRGLTNPEVDAGLLIDIMKQLLFSAKMMFVKAGQSQDLALCDSYISKVDVLHILVAAAYRHMPSLDQILQPASVTRLRNQLLEAEYYQLGVEVSTKTGLDSTGAWHAWGMACLKAGNLTAAREKFSRCLKPPLDLNQLSHGSRLVQDVVEYLESTVRPLVSLQDDDYFATLRELEATLRTQSLFLEAIPDGKIMNNTYYQECLFYLHNYSTNLAIISFYMRHNCLREALLHLLNKESPAEVFIEGIFQPSYKSGKLHTLENLLESIDPTLESWGAYLIAACQHLQKKNYYHILYELQQFMKDQVRAAMTCIRFFSHKAKSYTELGEKLSWLLKAKDHLKIYLQENSRSSGRKKTTFFRKKMAAADVSRHMNTLQLQMEVTRFLHRCESARTSQITTLPLPTLFGNNHMKMEVACQVMLGGKNVEDGFGIAFRVLQDFQLDAAVTYCRAARQLVEKEKYGEIRQLLKCVSESGMAAKSDGDTILLNCLEAFKRIPPQELEGLIQAIHSDDNKVRAYLTCCKLRSAYLIAVKQEHTQA", "output": "Phosphatidylinositol 3-phosphate-binding protein required for the abcission step in cytokinesis: recruited to the midbody during cytokinesis and acts as a regulator of abcission. May also be required for efficient homologous recombination DNA double-strand break repair (By similarity)."}]}
+{"id": "function_test_609", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTITYTNKVANARLGSFSSLLLCWRGSIYKLLYGEFLVFIFLYYSIRGLYRMVLSSDQQLLFEKLALYCDSYIQLIPISFVLGFYVTLVVSRWWSQYENLPWPDRLMIQVSSFVEGKDEEGRLLRRTLIRYAILGQVLILRSISTSVYKRFPTLHHLVLAGFMTHGEHKQLQKLGLPHNTFWVPWVWFANLSMKAYLGGRIRDTVLLQSLMNEVCTLRTQCGQLYAYDWISIPLVYTQVVTVAVYSFFLACLIGRQFLNPNKDYPGHEMDLVVPVFTILQFLFYMGWLKVAEQLINPFGEDDDDFETNWIIDRNLQVSLLSVDGMHQNLPPMERDMYWNEAAPQPPYTAASARSRRHSFMGSTFNISLKKEDLELWSKEEADTDKKESGYSSTIGCFLGLQPKNYHLPLKDLKTKLLCSKNPLLEGQCKDANQKNQKDVWKFKGLDFLKCVPRFKRRGSHCGPQAPSSHPTEQSAPSSSDTGDGPSTDYQEICHMKKKTVEFNLNIPESPTEHLQQRRLDQMSTNIQALMKEHAESYPYRDEAGTKPVLYE", "output": "Forms calcium-sensitive chloride channels. Permeable to bicarbonate (By similarity)."}]}
+{"id": "function_test_610", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MATGQKLMRAIRVFEFGGPEVLKLQSDVAVPIPKDHQVLIKVQACGVNPVDTYIRSGTHNIKPLLPYTPGFDVAGIIEAVGESVSAFKKGDRVFTTRTISGGYAEYALAADHTVYTLPEKLDFKQGAAIGIPYFTAYRALLHSACVKPGESVLVHGASGGVGIAACQIARAYGLKVLGTASTEEGQKIVLENGAHKVFNHKEADYIDKIKKSVGEKGVDVIIEMLANVNLSNDLNLLSHGGRVIVVGSRGTIEINPRDTMTKESSIKGVTLFSSTKEEFQQFAAALQAGMEIGWLRPVIGPQYLLEKATQAHENIIHSSGATGKMILLLN", "output": "Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species and enhances their stability. NADPH binding interferes with mRNA binding (By similarity). Has minimal or no quinone reductase activity. Binds strongly to single-stranded DNA."}]}
+{"id": "function_test_611", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MYRIGELAKMAEVTPDTIRYYEKQQMMEHEVRTEGGFRLYTESDLQRLKFIRHARQLGFSLESIRELLSIRIDPEHHTCQESKGIVQERLQEVEARIAELQSMQRSLQRLNDACCGTAHSSVYCSILEALEQGASGVKSGC", "output": "Zinc-responsive transcriptional regulator of zntA."}]}
+{"id": "function_test_612", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSQYGFVRVPREVEKAIPVVNAPRPRAVVPPPNSETARLVREYAAKELTAPVLNHSLRVFQYSVAIIRDQFPAWDLDQEVLYVTCLLHDIATTDKNMRATKMSFEYYGGILSRELVFNATGGNQDYADAVTEAIIRHQDLTGTGYITTLGLILQIATTLDNVGSNTDLIHIDTVSAINEQFPRLHWLSCFATVVDTENSRKPWGHTSSLGDDFSKKVICNTFGYN", "output": "Cyanamide hydratase involved in the detoxification and/or utilization of cyanamide, a toxic nitrile compound distributed widely in the environment."}]}
+{"id": "function_test_613", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSSTMLDDVDNNMMGIKSISLYELLSDVVKQGDKTRLVTAGPEQVLPDLIRHITETIPFDLFINLKNEMNDARNLVTRLNWLGKFLNDNFLQNHTFPFTILRICELCYDPFKYYKINELEKFVNALEKCCMVTSSWQVFDKTHGEKQEDDKEKDINFIKNQEDVSLMKIPWMTENNTRELAPFIREIDSIMSVNLGYDDEDEEEGFFDGDEDREMGNKSKRNVLLKDENFMVEEYYEDDCGINDDNSDNKGQNCQSDVTKNNSDDEDDDDNDDDYREDGADEDDEDDDHMGSTDDDEDDDEDRQAGESTKVQNFDKKNETPRKRKPTDLDNFEYDESPSFTNMDLTTPKKYKHTATGRFSIIESPSSSLLNAMDGSNEISSSQEEEKEDAHENHEGRSEGLLPGDELVSPSMSSSQEDKMVAIAGITYRENISSPLGKKSR", "output": "Regulatory subunit of the histone H2A phosphatase complex, which dephosphorylates H2AS128ph (gamma-H2A) that has been displaced from sites of DNA lesions in the double-stranded DNA break repair process. Dephosphorylation is necessary for efficient recovery from the DNA damage checkpoint."}]}
+{"id": "function_test_614", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTMKQFEIAAIPGDGVGKEVVAAAEKVLHTAAEVHGGLSFSFTAFPWSCDYYLEHGKMMPEDGIHTLTQFEAVFLGAVGNPKLVPDHISLWGLLLKIRRELELSINMRPAKQMAGITSPLLHPNDFDFVVIRENSEGEYSEVGGRIHRGDDEIAIQNAVFTRKATERVMRFAFELAKKRRSHVTSATKSNGIYHAMPFWDEVFQQTAADYSGIETSSQHIDALAAFFVTRPETFDVIVASNLFGDILTDISSSLMGSIGIAPSANINPSGKYPSMFEPVHGSAPDIAGQGLANPIGQIWTAKLMLDHFGEEELGAKILDVMEQVTADGIKTRDIGGQSTTAEVTDEICSRLRKL", "output": "Has multiple catalytic activities. Apart from catalyzing the oxidation of (+)-tartrate to oxaloglycolate, also converts meso-tartrate to D-glycerate and catalyzes the oxidative decarboxylation of D-malate to pyruvate."}]}
+{"id": "function_test_615", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGVLRSTQSMQAEVEEMRAALLHGHGGGAAAAAAAGWRPSAGDADVKRTAGGDGGAAGPRTVCVTGGISFVGFAVVDRLLRHGYTVRLALETQEDLDKLREMEMFGEDGRDGVWTVMANVTDPESLHRAFDGCAGVFHTSAFVDPGGMSGYTKHMASLEAKAAEQVIEACVRTESVRKCVFTSSLLACVWRQNYPHDRRFPTIIDENCWSDESFCRDNKLWFALGKTAAEKTAWRAARGRDLKLVTVCPALVTGPGFRRRNSTASIAYLKGARAMLADGLLATASVETVAEAHVRVYEAMGDNTAGGRYICYDHVVKRPEEFAELERQLGIPRRAAAAAAAQDSGDRPARFDLCRQKLARLMSTRRRCTYDDYYSVAFD", "output": "Involved in defense response. Required for NPR1/NH1-mediated resistance to the bacterial blight pathogen Xanthomomas oryzae pv. oryzae (Xoo). Required for pathogenesis-related (PR) genes expression. May be involved in lignin biosynthesis."}]}
+{"id": "function_test_616", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTYKYNCCDDGSGTTVGSVVRFDNVTLLIDPGWNPSKVSYEQCIKYWEKVIPEIDVIILSQPTIECLGAHSLLYYNFTSHFISRIQVYATLPVINLGRVSTIDSYASAGVIGPYDTNKLDLEDIEISFDHIVPLKYSQLVDLRSRYDGLTLLAYNAGVCPGGSIWCISTYSEKLVYAKRWNHTRDNILNAASILDATGKPLSTLMRPSAIITTLDRFGSSQPFKKRSKIFKDTLKKGLSSDGSVIIPVDMSGKFLDLFTQVHELLFESTKINAHTQVPVLILSYARGRTLTYAKSMLEWLSPSLLKTWENRNNTSPFEIGSRIKIIAPNELSKYPGSKICFVSEVGALINEVIIKVGNSEKTTLILTKPSFECASSLDKILEIVEQDERNWKTFPEDGKSFLCDNYISIDTIKEEPLSKEETEAFKVQLKEKKRDRNKKILLVKRESKKLANGNAIIDDTNGERAMRNQDILVENVNGVPPIDHIMGGDEDDDEEEENDNLLNLLKDNSEKSAAKKNTEVPVDIIIQPSAASKHKMFPFNPAKIKKDDYGTVVDFTMFLPDDSDNVNQNSRKRPLKDGAKTTSPVNEEDNKNEEEDGYNMSDPISKRSKHRASRYSGFSGTGEAENFDNLDYLKIDKTLSKRTISTVNVQLKCSVVILNLQSLVDQRSASIIWPSLKSRKIVLSAPKQIQNEEITAKLIKKNIEVVNMPLNKIVEFSTTIKTLDISIDSNLDNLLKWQRISDSYTVATVVGRLVKESLPQVNNHQKTASRSKLVLKPLHGSSRSHKTGALSIGDVRLAQLKKLLTEKNYIAEFKGEGTLVINEKVAVRKINDAETIIDGTPSELFDTVKKLVTDMLAKI", "output": "RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. May be involved in poly(A)-site recognition. May be involved in the association of the CPF, CPFIA and RNA polymerase II complexes."}]}
+{"id": "function_test_617", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSHEWLISASETMRSIGNGEGLRDKGAVVANNDGEFNEGDTNREEDSSTIFSFDFDEEIVMCIDFSGGKLGCSILDYHTKTLKAFDQDYVVNKTTISSHDLIDDADMSSNDISLLLGLLIMEANPTVCLVPARLEDWIFDYIKTKCDEINCRLELQPIKRFKKWDLLQSLQLRGHDNQTILNDILSNSKFTTTVTLGTVGCILANHEQLGEYNDSTASSNMVTGRLVQNAFEDVIHGIRYIDIRDRMVLDENTISALHIFPTAHKLGHDKMMRNGFFSVFELFNQVSSDYARRILKSWLINPLTNKKRIETRYSIIRTLLDKQNAIIFSDLSQSIKRCPDAFGFINQLRSGKSTLGTWSKVASFLEKGIAIFQLVSSLKLGSDEANILHDIKNKVDISALKECLRKVETVIDFDTSRDTKTLTINTGVDNRLDECRNIYNHLEGILLDVARETQIFLLNTMPQEDCKTTKSLEKLVNAVYIPQLGYLVTISVLMEPLLDGIPNLQWEEIFRSSENIYFKNGRVLELDETYGDIYGAISDFEIEILFSLQEQILRRKTQLTAYNILLSELEILLSFAQVSAERNYAEPQLVEDECILEIINGRHALYETFLDNYIPNSTMIDGGLFSELSWCEQNKGRIIVVTGANASGKSVYLTQNGLIVYLAQIGCFVPAERARIGIADKILTRIRTQETVYKTQSSFLLDSQQMAKSLSLATEKSLILIDEYGKGTDILDGPSLFGSIMLNMSKSEKCPRIIACTHFHELFNENVLTENIKGIKHYCTDILISQKYNLLETAHVGEDHESEGITFLFKVKEGISKQSFGIYCAKVCGLSRDIVERAEELSRMINRGDDVVQQCGNLTEKEMREFQKNQEIVKKFLSWDLDLETTTTSENLRLKLKNFLR", "output": "Involved in meiotic recombination. Facilitate crossovers between homologs during meiosis."}]}
+{"id": "function_test_618", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSKPSYKVADISLAEWGRKAIIIAENEMPGLMACRKKYGPSKPLKGARITGCLHMTVQTAVLIETLVELGAQVQWSSCNIFSTQDNAAAAIAATGVPVYAWKGETDEEYMWCIEQTLVFPDGQPLNMILDDGGDLTNLVHEKFPQYLKNIKGLSEETTTGVHNLYKMFKEGRLGVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVCCVAGYGDVGKGCAQALKGFGGRVIVTEVDPINALQAAMEGYEVTTMEEASKEASIFVTTTGCRDIITSVHLQQMPDDAIVCNIGHFDIEIDVDWLNANAKEKVNVKPQVDRYTMQSGKHIILLAEGRLVNLGCAHGHPSFVMSNSFTNQVLAQIELWTKSDKYAVGVHVLPKILDEEVASLHLEKLGVKLTKLTEKQATYLGVSQTGPFKPDHYRY", "output": "Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine."}]}
+{"id": "function_test_619", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKVVNLKQAILQAWKERWSDYQWAINIKKNCPKGATWDYLNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSSVLTAISKFDDFSRELCVKSLLEIMDMFSNRLSCHGKAEECIGLCRAMLCTVVWLLQGCAWYCERLRDPNDFSALESSLRACLERMANLLHSTKNRALVHIARLEEQASWTNVEQAVLKLTENLSAVTNPTLKESLEECVSLVKSIPQMLCLQCDPPVHTTFPSVHAFIMLEGTMNLTGETQPLVEQLMMIKRMQRIPAPLFVLEIWKACFTGLIESPEGNEELKWTAFTFLKIPQVLLRLKKYPQGEKTQDFTEDVNVAFEYLLNLTPLLDKADQRCNCDCLSLLLQECNKLGLLSEANTATLTAKRSEDREHAPRLKTAENANIQPNPGLILRAEPTVTNILKTVDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIKLNEFPKHISGEGSKSASVRALLFDISFLMLCHVVQTYGSEVILSDPSPSSETPFFETWLQTCMPEEGKTLNPDHPCFRPESGKVESLVALLNSSSEMKLVQMKWHEICLSTPAAILEVLNAWENGVLSVEAVQKITDNIKGKVCSMAICAVAWLVAHVRMLGLDEREKPQTMIRQLMTPMSGENTLQFYHERVVIMSSILEHMCADVFQQTGLSLRPAVEGQEPIPYRNLLPARLPIRQALQSQFRKVLEKGWVDSHAFHLFENLLHMGGVFWFTNNLVKELLKETRKEWASRVVELLYSIFCLDTQQITLTLLGHILPRLLTDPAHWHSLADPPGRALAKLSVWCALSSYSSHHKGQASARQRKRHREDIEDYTSLFPLDDTQPSKLMRLLSSNEDENSMLSSPGDRSISSSLSASQLHTVNMRDPLNRVLANLFLLISSQLGSKTAGPHTQFVQSFVEECVDCSEQGSRSSILQFMPFTMISELVKLQSLAKPKTVLSITDLSLPLGRRMAAKAIAAL", "output": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). Required for proliferation of enteric nervous system precursors. Required for the development of dopaminergic amacrine cells and rod photoreceptor cells in the retina."}]}
+{"id": "function_test_620", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSYDYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVTVDGRPIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRETFNHLASWLEDARQHANPNMSIMLIGNKCDLAHKRAVSKEEGQQFAKEHGLLFLEASARTAQNVEEAFIETAAKILQNIQDGVFDVSNESSGIKIGYGRTQGAAGGRDGTISQGGGCCG", "output": "Intracellular vesicle trafficking and protein transport."}]}
+{"id": "function_test_621", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNTTSTHFVPPRRFEVYEPLNQIGMWEESFKNNGDMYTPGSIIIPTNEKPDSLSEDTSHGTEGTPHKFDQEASTSRHPDKIQRRLAQNREAARKSRLRKKAYVQQLETSRLKLIHLEQELDRARQQGFYVGNGVDTNALSFSDNMSSGIVAFEMEYGHWVEEQNRQICELRTVLHGQVSDIELRSLVENAMKHYFQLFRMKSAAAKIDVFYVMSGMWKTSAERFFLWIGGFRPSELLKVLLPHFDPLTDQQLLDVCNLRQSCQQAEDALSQGMEKLQHTLAESVAAGKLGEGSYIPQMTCAMERLEALVSFVNQADHLRHETLQQMHRILTTRQAARGLLALGEYFQRLRALSSSWAARQREPT", "output": "Transcriptional activator that binds specifically to the DNA sequence 5'-TGACG-3'. Recognizes ocs elements like the as-1 motif of the cauliflower mosaic virus 35S promoter. Binding to the as-1-like cis elements mediate auxin- and salicylic acid-inducible transcription. May be involved in the induction of the systemic acquired resistance (SAR) via its interaction with NPR1. Could also bind to the Hex-motif (5'-TGACGTGG-3') another cis-acting element found in plant histone promoters."}]}
+{"id": "function_test_622", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQACEGSAAGRRAFDSICPNRMLDLSRRTLGKPGKPERKFVPSWKSFSGCGGGSPVAVYEDPPDAEPAPLPALTTIDLQDLADCTSLLGTEASPSGDSSASQNPSLQTEEDFNLQNFRDAMDDLIADSSSLMSPPLTNSDFPFSPCDVSSFGSCLSPSLDPPALGSPDLPPPPTEQYWKEVADQNQRALGTALIENNQLHVTLTQKQEEIASLRERNVQLKELASRTRHLASVLDKLMITQSPAEPFQIKATTKRSLEELFCAAGQAGQGCAEVDAILRDISQRCEEALHNRDPKRPRLQPEPDSKDCSSRNLHGAFRGLRTDCSASSVNLSHSELEEGGSFSTPIRSHSTIRTLAFPQGKAFTIRTVTGGYKFRWVPS", "output": "Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1."}]}
+{"id": "function_test_623", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDVTTSAWSETTRRISEPSTLQGTLGSLDKAEDHSSSIFSGFAALLAILLVVAVICVLWCCGKRKKRQVPYLRVTIMPLLTLPRPRQRAKNIYDLLPRRQEELGRHPSRSIRIVSTESLLSRNSDSPSSEHVPSRAGDALHMHRAHTHAMGYAVGIYDNAMRPQMCGNLAPSPHYVNVRASRGSPSTSSEDSRDYVNIPTAKEIAETLASASNPPRNLFILPGTKELAPSEEIDEGCGNASDCTSLGSPGTENSDPLSDGEGSSQTSNDYVNMAELDLGTPQGKQLQGMFQCRRDYENVPPGPSSNKQQEEEVTSSNTDHVEGRTDGPETHTPPAVQSGSFLALKDHVACQSSAHSETGPWEDAEETSSEDSHDYENVCAAEAGARG", "output": "Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells."}]}
+{"id": "function_test_624", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEELEQGLLMQPWAWLQLAENSLLAKASITKHGYALLISDLQQVWHEQVDTLEVSQRAKELNKRLTAPPAAFLHHLDEVLRPLFKDSAHQDAAHPSKATFSCDRGEEVLILRVRSELSGLPFNWHFHCLPASSLLVSQHLICPLMGVSLALHSHVRELAALLRMKDLEIQAYQESGAVLSRGRLKTEPFEENSFLEQFMVEKLPEACAVGDGRPFAMNLQSLYVAVTKQQVQARQKHKGSGEPQTSSSTSPQGTDSQLQNQPEQQISPTPTLSEPECEPMAASGPVHRAQLVKAKRKKPRGLFS", "output": "DNA repair protein involved in DNA non-homologous end joining (NHEJ); required for double-strand break (DSB) repair and V(D)J recombination. Plays a key role in NHEJ by promoting the ligation of various mismatched and non-cohesive ends. Together with PAXX, collaborates with DNA polymerase lambda (POLL) to promote joining of non-cohesive DNA ends. May act in concert with XRCC5-XRCC6 (Ku) to stimulate XRCC4-mediated joining of blunt ends and several types of mismatched ends that are non-complementary or partially complementary. Associates with XRCC4 to form alternating helical filaments that bridge DNA and act like a bandage, holding together the broken DNA until it is repaired. The XRCC4-NHEJ1/XLF subcomplex binds to the DNA fragments of a DSB in a highly diffusive manner and robustly bridges two independent DNA molecules, holding the broken DNA fragments in close proximity to one other. The mobility of the bridges ensures that the ends remain accessible for further processing by other repair factors. Binds DNA in a length-dependent manner."}]}
+{"id": "function_test_625", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTTAAERKYINIRKRLDQLGYRQTLSVDSLPLVEKLFSDLVHTTESLRQCRLSSGKAEKESANLDFVLEPYKLENTRLNKENNELYLELMKLRECSDKHIKDLKTTLKKCSRETADLKFLNNQYVHKVKVLEKESKAKDEKIQQLQEKNLRAVVQTPGGRKRNIAFRRQRMQIDEPAPPSEVSAYPVPQPEDPYIADLLQVADNRIQELQEEVQQLQEKLAQMEKGVLDYSKQIELREREIQRLSLALDGGCSPDVLSLETRNKTNEKLIAHLNVQVDFLQQANKELEKHIQELMETKETVTTEVVNLSNRNEKLCQELTEIDQLAQRLERHKEQVLETADKELGEAKKEIKRNLCEMRNLEEKMSKLQWELDLSHKEKERLNSELLLKSDLETVVHQLEQEKQRLSKKLQSFAVTERELTLEVERMRLEHGIKRRDKSPSRLDTFLKGIEEERDYYKKELEKLQHLIQRRSCAINYSAREKPPVVKCSEKGDCSTDVHLITRERDELQRMLERFEKYMEDIQSNVKLLTAERDKLNVLYKEAKEELSTLRKESTNSTSPNHLVSCVEKEKERALSELRRITAEKEALREKLKNIQERNAVGKSDLEKTIEHLTYINHQLENEKYELQSKMLMMKETVESLENKSKLQAQKLSHVTGDSSHQKTEMTSLRIVSEQLQRSLDDCQHRLSIKRGELESAQEQIKMLEQKLENLSHRMTVQSEETHAMKKTIGVMDKEKDFLQETVDEKTEKIANLQESLLSKEKVIAQLKVTVAEYETSLNQLQETLTTRDREINSLRRQLDASHKELDDVGKSREISFKENRRLQDDLATMARENQEISLELEAAVQEKEEMKSRVHKYITEVSRWESLMAAKEKENKDLLDRFQMLHSRAEDWEVKAQQAEGENSSVRLELLSIDTERRHLRERVDLLEKEIQEHINAHHAYESQISSMAKAMSQLEEELRRHESEKATMLGDVSSLRELCIKLDSGKDVMTQQLNSKSLELERAVAELENVKSESELLKKQLTNERQTIKNLESLLATNRDKEFQSHLTSHEKDTEIQLLKEKLNLSESKLTTQSRETSMLRTKVTQLQTDYDNLKRQMSNEKYERERAIQEMRRLGLPTSPLSSTLKSPVQTPDHINA", "output": "Centrosomal protein involved in centriole biogenesis. Acts as a scaffolding protein during early centriole biogenesis. Required for the targeting of centriole satellite proteins to centrosomes such as of PCM1, SSX2IP and CEP290 and recruitment of WRAP73 to centrioles. Also required for centriole-centriole cohesion during interphase by acting as a platform protein for CEP250 at the centriole. Required for the recruitment of CEP295 to the proximal end of new-born centrioles at the centriolar microtubule wall during early S phase in a PLK4-dependent manner (By similarity)."}]}
+{"id": "function_test_626", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEQYEVVEQIGRGAYGSAYLVVHKGERKRYVMKKIRLSKQNDKFQRTAYQEMSLMASLSNPYIVEYKDGWVDEGTSACIVTSYCEGGDMAERIKKARGVLFSEERVCRWFTQLLLALDYLHCNRVLHRDLKCSNILLTKDNNIRLADFGLAKLLMEDLASTIVGTPNYMCPEILADIPYGYKSDIWSLGCCMFEILAHRPAFKAADMASLINKINRSSISPMPPIYSSSLKQIVKSMLRKNPEHRPTAGELLRHPYLQPYLAESCSCSPIYLPVKPTKSNLGDKQQSRKPGSGRKRIIKTNGSSEALETAAEQAVDTRDNSTYISDVSTVGTQDACISQVSVDPQARNKAYQNIDDLTLFQQIEENLMTITDRQIDEAIFLKAVRTSSTVDVVPVSGAIQKPNEAPIPKEELTIGVVQEQRKEVKAHTHQGSKPGTGDVPIVTEESSPKSAVKLAHSDSTPAEWDHLNIVQQRADALESLLELCAKLLKQERLEELAGVLRPFGEGAVSSRETAIWLTKSLMTPPKLEGSPKLT", "output": "May be involved in plant development processes."}]}
+{"id": "function_test_627", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKYCKFCCKAVTGVKLIHVPKCAIKRKLWEQSLGCSLGENSQICDTHFNDSQWKAAPAKGQTFKRRRLNADAVPSKVIEPEPEKIKEGYTSGSTQTESCSLFNENKSLREKIRTLEYEMRRLEQQLRESQQLEESLRKIFTDTQIRILKNGGQRATFNSDDISTAICLHTAGPRAYNHLYKKGFPLPSRTTLYRWLSDVDIKRGCLDVVIDLMDSDGVDDADKLCVLAFDEMKVAAAFEYDSSADIVYEPSDYVQLAIVRGLKKSWKQPVFFDFNTRMDPDTLNNILRKLHRKGYLVVAIVSDLGTGNQKLWTELGISESKTWFSHPADDHLKIFVFSDTPHLIKLVRNHYVDSGLTINGKKLTKKTIQEALHLCNKSDLSILFKINENHINVRSLAKQKVKLATQLFSNTTASSIRRCYSLGYDIENATETADFFKLMNDWFDIFNSKLSTSNCIECSQPYGKQLDIQNDILNRMSEIMRTGILDKPKRLPFQKGIIVNNASLDGLYKYLQENFSMQYILTSRLNQDIVEHFFGSMRSRGGQFDHPTPLQFKYRLRKYIIGMTNLKECVNKNVIPDNSESWLNLDFSSKENENKSKDDEPVDDEPVDEMLSNIDFTEMDELTEDAMEYIAGYVIKKLRISDKVKENLTFTYVDEVSHGGLIKPSEKFQEKLKELECIFLHYTNNNNFEITNNVKEKLILAARNVDVDKQVKSFYFKIRIYFRIKYFNKKIEIKNQKQKLIGNSKLLKIKL", "output": "P-element transposase that specifically mediates transposition of P-elements. Mediates both; precise and imprecise excision."}]}
+{"id": "function_test_628", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MESSFSFGVILAVLTILIIAVNALVVVAMLLSIYKNDGVGLCFTLNLAVADTLIGVAISGLVTDQLSSSAQHTQKTLCSLRMAFVTSSAAASVLTVMLIAFDRYLAIKQPLRYFQIMNGLVAGACIAGLWLVSYLIGFLPLGVSIFQQTTYHGPCSFFAVFHPRFVLTLSCAGFFPAVLLFVFFYCDMLKIASVHSQQIRKMEHAGAMAGAYRPPRSVNDFKAVRTIAVLIGSFTLSWSPFLITSIVQVACHKCCLYQVLEKYLWLLGVGNSLLNPLIYAYWQREVRQQLYHMALGVKKFFTSILLLLPARNRGPERTRESAYHIVTISHPELDG", "output": "Receptor for the endogenous fatty-acid ethanolamide oleoylethanolamide (OEA) and lysophosphatidylcholine (LPC). Functions as a glucose-dependent insulinotropic receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Seems to act through a G(s) mediated pathway."}]}
+{"id": "function_test_629", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNTKLSLSQTKIFTFTTWFNDTRSGLDRRSSISPTLCSKPVYSGKLKAAKETARIETSNTKNASIEDSFFSKIAINYLSKNLQDAAGISSSSKSTDYDRLVDTATRVSRNFDTKQQHEFVLSSLDRALPTVISSLIKMAFPPSKVSRELFALFTTISFAWLVGPSEVRETEVNGRKEKSVVYIEKCRFLEQSNCVGMCTHICKIPSQIFIKNSLGMPIYMEPDFNDLSCKMMFGREPPEIEDDPAMKQPCFEFCKSNKSYGVKH", "output": "Involved in strigolactones biosynthesis by catalyzing the isomerization of the C9-C10 double bond in all-trans-beta-carotene leading to 9-cis-beta-carotene and providing the substrate for CCD7. Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate-limiting conditions and function as rhizosphere signal that stimulates hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds."}]}
+{"id": "function_test_630", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAAPMDCLESLEGDGDAGRRASGVEVALPSNPTAPAPLCPHGPTLLFVKVNQGKEETRKFYACSACRDRKDCNFFQWEDEKLSEARLAAREIHNQKCQPPLSRAQCIERYLSFIQLPLAQRKFCQSCQQLLLPADWREHGTHQLSADISVAQLGRPSQLLYPLENKKTHAQYLFADRSCQFLAGLLATLGFSRVLCVGAPRLHEQIRLTASGERSGMRSLLLDIDFRYSQFYLEGSFCRYNMFNHHFFDGKAALEVCKEFLQEEEGKGVIMVTDPPFGGLVEPLAITFKKLIAMWKEGQSQDDSHKELPIFWIFPYFFESRICQFFPSFCMLDYQVDYDNHALYKHGKTGRKQSPVRIFTNVPPNKIILPSEEGYRFCSLCQRYVSRENQHCVHCNSCTSKDGRKWSHCFLCKKCVKPSWIHCNTCNRCALPDHSCLGPKDGCFICGALDHKRSNCPNIGTSWRANKLVEFFGFLEKRLLMSSFLGAIYRSTKLSEDSEFFRVLNRSSHHYV", "output": "rRNA N6-methyltransferase that specifically methylates the adenine in position 4220 of 28S rRNA. N6-methylation of adenine(4220) in 28S rRNA is required for translation."}]}
+{"id": "function_test_631", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTEAMIRNKPGMASVKDMPLLQDGPPPGGFAPVRYARRISNTGPSAMAMFLAVSGAFAWGMYQVGQGNKIRRALKEEKYAARRTILPILQAEEDERFVSEWKKYLEYEADVMKDVPGWKVGENVYNSGRWMPPATGELRPDVW", "output": "Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)."}]}
+{"id": "function_test_632", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGSSTGDLVTRIQSAHRFDHDALFRFAADNVSGFPTNPSQFKVSQFGHGQSNPTFLIEVGSGSSLKRYVLRKKPPGKLLQSAHAVDREFQVLRALGEHTQVPVPKVFCLCTDPAVIGTAFYIMEFMEGRIFIDPKLPNVAPERRNAIYRATAKALASLHSADVDAIGLEKYGRRGNYCKRQIDRWFKQYLASTSEGKPERNPKMFELVDWLRKNIPAEDSTGATSGLVHGDFRIDNLVFHPSEDRVIGIIDWELSTLGNQMCDVAYSCMHYIVNVQLDKEHVSEGFETTGLPEGMLSMPEFLLEYCSASGKPWPAANWKFYVAFSLFRAASIYTGVYSRWLMGNASAGERARNTGVQANELVESALGYIARENVLPEHPPSVQRDVSPSYESLVDGSGRFIPNRKVLELRQKLIKFMETHIYPMENEFSKLAQSDMRWTVHPQEEKLKEMAKREGLWNLFVPVDSAARARRELAATENKHNLSGKSFDQLFGEGLTNLEYGYLCEIMGRSVWAPQVFNCGAPDTGNMEVILRYGNKEQISEWLIPLLEGRIRSGFAMTEPQVASSDATNIECSIRRQGDSYVINGTKWWTSGAMDPRCRVLILMGKTDFNAPKHKQQSMILVDMRTPGISVKRPLTVFGFDDAPHGHAEISFENVVVPAKNILLGEGRGFEIAQGRLGPGRLHHCMRLIGAAERGMELMAQRALSRKTFGKFIAQHGSFVSDLAKLRVELEGTRLLVLEAADHLDKFGNKKARGILAMAKVAAPNMALKVLDTAIQVHGAAGVSSDTVLAHLWATARTLRIADGPDEVHLGTIGKLELQRASKL", "output": "Involved with IBR1 and IBR10 in the peroxisomal beta-oxidation of indole-3-butyric acid (IBA) to form indole-3-acetic acid (IAA), a biologically active auxin . May be responsible for catalyzing the first step in IBA-CoA beta-oxidation . May play a role in defense response to pathogenic bacteria ."}]}
+{"id": "function_test_633", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MASLISFSLLPKPKAVRSSISAPQTQTINTEKLEDKFGRKGIKFSESNNIPMVELKVRNGSSLKLSLSDAHVLSYKPKVYWKDEGFEEVLYTVDGDESRGGVGVVIVNGEEPKGGSSVISGCDWSVKDTDSDAIDALQIELSCTAGVLDITYIVSLYPVSMATALVVKNNGRKPVTLKPGIMSYLRFKKRSGAGIQGLKGCSYCPNPPLSSPFELLSPSEAMKAESSGWFGSEEGEKPGIWAVEDSVITLLEKKMSRIYGAPPAERLKAVYNTPPSKFETIDQGRGLFFRMIRIGFEEMYVGSPGSMWDKYGKQHYFVCTGPTSMLVPVDVASGETWRGAMVIEHDNL", "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_634", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPKVKALQCALALEIRSVTCPGVLLKDKEDIYLSICVFGQYKKTQCVPATFPLVFNARMVFEKVFPEAVDPGDVVAQLEYDTAVFELIQLVPPVGETLSTYDENTRDFMFPGPNQISGHHDSNRQVTMRRISGLRGIAPKLEFSTTSVITECLISSRKCRTQDKFTYHSAPVEKPHGRLQCRTSRSQKKKSKSPERSKYCINTKNYEQPTISSKSHSPSPYTKRRMCELSEDTRRRLAHLNLGPYEFKKETDKPPFVIRHVDPPSPRADNFFGSPGRDCERDGWVRMHSDHPHLGCCRAKDYKVIRSPHGRDFEDPFERCEDYLSPRTCSKPQHSARTLLVHSAPSTTPKHCASPVLNRASLRERFHSDWCSPPNCDEIHDRVKDVLKSHQAHGRHLCEERDPEKEDELELKRSLLYRDSAYDSDPEYSSFQRPRGSFHLDDGECWSNRAASCKGKSHRPVFENSMDKMYRNLYQKACSSVSHTQESF", "output": "Required for formation of the sperm connecting piece during spermiogenesis. Sperm connecting piece is essential for linking the developing flagellum to the head during late spermiogenesis. May be involved in myosin-based microfilament transport through interaction with myosin subunits."}]}
+{"id": "function_test_635", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNQEAASNLGLDLKLNISPSLDSSLLTESSSSSLCSEEAEGGGGEAKSMVVVGCPNCIMYIITSLENDPRCPRCNSHVLLDFLTGNHSKKSTS", "output": "Involved in ethylene-dependent salt stress responses by reducing reactive oxygen species (ROS) accumulation."}]}
+{"id": "function_test_636", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSAKLLYNLSDENPNLNKQIGCMNGIFQVFYRQHYPPRRVTGDELKSLPSGKASDNVGDTNISADKKETEKSKKKKTAKEKQRGVSSESSSRLSFSSSPCSSSFSSADISTTASQFEQPGLSNGENPVREPTNGSPRWGGLMMPSDIRELVRSSIHKETRTRDEEALSQQPKSARANVSLLKESSPSRNSNEWSEGRRVVKLKDSPRFSYDERETRKTGAKLKETPRLSLDSRSNSFRSARSSCSPEPQELVTGHRRTTSSVVAKLMGLEVIPDEPVTIQNRENRFCDSPRPTSRVEVDLQRSRGFDSIKKMMPAKFPMKASPWAQVDGAKNQVKIPDATTLTVYGEIQKRLSQLEFKKSEKDLRALKQILEAMEKTQQLISKDDDDNKTLCSSNFMQRNNQPIPSAINTSSMNFKSSSIVVMKAATAPVFKDTGIAGSASFSPRNVALPNVKVGNLRQAQKVIPRKQSAMDVTPRPGYYKGQTESTMKNTSTRPLQSKSDMAKSGKIQKPSVSLRTPPKKLGFEKQSRPTSPKPELNKNQRQQLSRQQTESASPRRKPGIKSRGLQQSEDRLSDESSDLRSLRSDSNVSLASNLDTEVTSRYNYERNSDITEQHTPKQRSPDLGMRSLSKPLKVTVEQPSPVSVLDVAFDEDDSPSPVRKISIVFKEDDNLSSEESHWMNKNNNLCRSIVWPESNTSLKQPDAELTEGFMEDDAEFKNGDHKYISEIMLASGLLRDIDYSMISIQLHQAHLPINPSLFFVLEQNKTSNVSLQDNKHKGRGFGQQQTVNLVERSKRKLIFDTINEILAHRFAAEGCTKQPSITLSISTQRTHEKSSRGEELLQTLCSEIDRLQDNSKCILDEDDEDLIWEDLQSHGMNWKEIEGETPGLVLDIERLIFKDLIGEVVTSEFAAFPRMLSGQPRQLFHC", "output": "In association with LNG2, regulates leaf morphology by promoting longitudinal polar cell elongation independently of ROT3."}]}
+{"id": "function_test_637", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNTTSSKSKKKQDDQVGTRFLGVRRRPWGRYAAEIRDPTTKERHWLGTFDTAEEAALAYDRAARSMRGTRARTNFVYSDMPPSSSVTSIVSPDDPPPPPPPPAPPSNDPVDYMMMFNQYSSTDSPMLQPHCDQVDSYMFGGSQSSNSYCYSNDSSNELPPLPSDLSNSCYSQPQWTWTGDDYSSEYVHSPMFSRMPPVSDSFPQGFNYFGS", "output": "Cell division-promoting factor involved in leaf blade differentiation, inflorescence branching, as well as in carpel and silique shape. Promotes the number of xylem cells. Regulates positively the gibberellin signaling pathway leading to germination, hypocotyl elongation, and leaf expansion. Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity)."}]}
+{"id": "function_test_638", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MYDDSYVPGFEDSEAGSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKARRSGNPSSLSDIGSRRSPPPSLAKQKQKQAEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSSIAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPAPGPGLLGPPSAIPGLQNQQLLGERGEEHSPLERDSLMPSDEASESSRQAWTGSSQRSSRHLEEDYADAYHDLYQPHRQHTSGLPSANGHDPQDRLLAQDSEHNHNERNWQRNRPWPKDSY", "output": "Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents . Increases CACNA1B peak calcium current and shifts the voltage dependencies of channel activation and inactivation . Increases CACNA1C peak calcium current and shifts the voltage dependencies of channel activation and inactivation (By similarity)."}]}
+{"id": "function_test_639", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MISLLKAREKLLSPLVSSTIRRLSSSLSYSREDSRDSEVLIHPSAVVHPNAVIGKGVSVGPYCTIGSSVKLGNGCKLYPSSHVFGNTELGESCVLMTGAVVGDELPGYTFIGCNNIIGHHAVVGVKCQDLKYKHGDECFLCIGNNNEIREFCSIHRSSKPSDKTVIGDNNLIMGSCHIAHDCKIGDRNIFANNTLLAGHVVVEDNTHTAGASVVHQFCHIGSFAFIGGGSVVSQDVPKYMMVAGERAELRGLNLEGLRRNGFTMSEMKSLRAAYRKIFMSTETVSLSFEERLTELEQDQELYSVPAVSAMLQSIRDSFTESRRGICKFRQWLDSTT", "output": "Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that in bacteria anchors the lipopolysaccharide to the outer membrane of the cell. Lipid A-like molecules in plants may serve as structural components of the outer membranes of mitochondria and/or chloroplasts, or may be involved in signal transduction or plant defense responses (Potential)."}]}
+{"id": "function_test_640", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNRTKGDEEEYWNSSKFKAFTFDDEDDELSQLKESKRAVNSLRDFVDDDDEDDLERVSWTGEPVGSISWSIKETAGNSGSSHEREQLKNRNSFSTYAQLPKPASTYSLSSFFRGRTRPGSFQSLSDALSDTPAKSYAPELGRPKGEYRDYSNDWSPSDTVRRLRKGKDKIQLLEEAVSMHDGNVITAVLIFLKRTLSKEILFRELEVRQVALRHLIHFLKEIGDQKLLLDLFRFLDRTEELALSHYREHLNIQDPEKRKEFLKTCIGLPFSAEDSAHIQDHYTLLERQIIIEANDRHLELAGQTEVFRKHPRKASILNMPLVTTLFYSCFYHYTEAEGTFSSPVNLKKTFKIPDKQYVLTALAARAKLRAWHDVDALFTTKNWLGYTKKRAPIGFHRVVEILHKNSAPVQVLQEYVNLVEDVDTKLNLATKFKCHDVVIDTCRDLKDRQQLLAYRSKVDKGSAEEEKIDALLNSSQIRWKN", "output": "Proposed to be involved in endosomal maturation implicating in part VPS33B. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical RAB11A-dependent recycling pathway and in the maintenance of the apical-basolateral polarity. May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be independent of VPS33B. May play a role in vesicular trafficking during spermatogenesis. May be involved in direct or indirect transcriptional regulation of E-cadherin (By similarity)."}]}
+{"id": "function_test_641", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MECIGKRVKSRSWQRLQAVNKRKKMETVAPVTSPPKKRRQKKPKNYDSDIEDITPTCNDSVPPPQVSNMYSVPNNSVKESFSRIMRDLNVEKKSGPSSSRLTDGSEQNPCLKERSFRVSDLGVEKKCSPEITDLDVGIPVPRFSKLKDVSEQKNTCLMQKSSPEIADLDLVISVPSSSVLKDVSEEIRFLKDKCSPEIRGLVLEKSVPGEIEILSDSESETEARRRASAKKKLFEESSRIVESISDGEDSSSETDEEEEENQDSEDNNTKDNVTVESLSSEDPSSSSSSSSSSSSSSSSSSSDDESYVKEVVGDNRDDDDLRKASSPIKRVSLVERKALVRYKRSGSSLTKPRERDNKIQKLNHREEEKKERQREVVRVVTKQPSNVVYTCAHCGKENTGNPESHSSFIRPHSIRDEIEDVNNFASTNVSKYEDSVSINSGKTTGAPSRPEVENPETGKELNTPEKPSISRPEIFTTEKAIDVQVPEEPSRPEIYSSEKAKEVQAPEMPSRPEVFSSEKAKEIQVPEMPSIPEIQNSEKAKEVQANNRMGLTTPAVAEGLNKSVVTNEHIEDDSDSSISSGDGYESDPTLKDKEVKINNHSDWRILNGNNKEVDLFRLLVNSVWEKGQLGEEDEADELVSSAEDQSQEQAREDHRKYDDAGLLIIRPPPLIEKFGVEEPQSPPVVSEIDSEEDRLWEELAFFTKSNDIGGNELFSNVEKNISANETPAAQCKKGKHDLCIDLEVGLKCMHCGFVEREIRSMDVSEWGEKTTRERRKFDRFEEEEGSSFIGKLGFDAPNNSLNEGCVSSEGTVWDKIPGVKSQMYPHQQEGFEFIWKNLAGTIMLNELKDFENSDETGGCIMSHAPGTGKTRLTIIFLQAYLQCFPDCKPVIIAPASLLLTWAEEFKKWNISIPFHNLSSLDFTGKENSAALGLLMQKNATARSNNEIRMVKIYSWIKSKSILGISYNLYEKLAGVKDEDKKTKMVREVKPDKELDDIREILMGRPGLLVLDEAHTPRNQRSCIWKTLSKVETQKRILLSGTPFQNNFLELCNVLGLARPKYLERLTSTLKKSGMTVTKRGKKNLGNEINNRGIEELKAVMLPFVHVHKGSILQSSLPGLRECVVVLNPPELQRRVLESIEVTHNRKTKNVFETEHKLSLVSVHPSLVSRCKISEKERLSIDEALLAQLKKVRLDPNQSVKTRFLMEFVELCEVIKEKVLVFSQYIDPLKLIMKHLVSRFKWNPGEEVLYMHGKLEQKQRQTLINEFNDPKSKAKVFLASTKACSEGISLVGASRVILLDVVWNPAVERQAISRAYRIGQKRIVYTYHLVAKGTPEGPKYCKQAQKDRISELVFACSSRHDKGKEKIAEAVTEDKVLDTMVEHSKLGDMFDNLIVQPKEADLVEGFSILMP", "output": "Probable chromatin remodeling factor."}]}
+{"id": "function_test_642", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAKMPLSVVVFLLFSAAFLAVSMAEIKSLVISDDARPMILFEKFGFTHTGHVTVSISSVSVVSTSSDPNPEASRLGFFLLSEESLLQVLLEIQQNPRFCVLDSHYVTHLFTFRDLSPPPNSRFNQSYPVTSPNEYSLFFANCVPETKVSMAVRTEMYNKDPNGSKDYLPAGSTQLPTLYSFFFLCYVAFLGFWSYTCWTNKQTVHRIHLLMAGLLLIKSLNLICAAEDKHYVKITGTPHGWDILFYIFQFIRVVLLFTVIILIGTGWSFLKPFLQEKEKNVLIIVIPLQVLANIASIVIGETGPFIKDWVTWNQVFLLVDIICCCAIIFPIVWSIRSLRETSKTDGKAARNLSKLTLFRQFYIVVIGYLYFTRIVVFALKTIAAYKYQWVSFAAEEIVSLVFYVIMFHMFRPEEKNEYFAVDDDEEEAAALALRDEEFEL", "output": "Plays a role in plants and microbes interactions . G-protein coupled receptor involved in root growth mediated by the bacterial quorum-sensing signals N-acyl-homoserine lactones (AHLs) ."}]}
+{"id": "function_test_643", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKSFGLCLFILVSSPCLLQANLSSDYYTKTCPEFEETLVQIVTDKQIAAPTTAVGTLRLFFHDCMVDGCDASILVASTPRKTSERDADINRSLPGDAFDVITRIKTAVELKCPNIVSCSDILVGATRSLISMVGGPRVNVKFGRKDSLVSDMNRVEGKLARPNMTMDHIISIFESSGLTVQEMVALVGAHTIGFSHCKEFASRIFNKSDQNGPVEMNPKYAAELRKLCANYTNDEQMSAFNDVFTPGKFDNMYYKNLKHGYGLLQSDHAIAFDNRTRSLVDLYAEDETAFFDAFAKAMEKVSEKNVKTGKLGEVRRRCDQYNDYKG", "output": "Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme/isoform in each plant tissue."}]}
+{"id": "function_test_644", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSAFVGKYADELIKTAKYIATPGKGILAADESTGTIGKRFASINVENIESNRQALRELLFTSPGTFPCLSGVILFEETLYQKTTDGKPFVELLMENGVIPGIKVDKGVVDLAGTNGETTTQGLDSLGARCQEYYKAGARFAKWRAVLKIGATEPSELSIQENAKGLARYAIICQENGLVPIVEPEVLTDGSHDIKKCAAVTETVLAAVYKALNDHHVLLEGTLLKPNMVTPGSDSPKVAPEVIAEYTVTALRRTVPPAVPGIVFLSGGQSEEEATLNLNAMNKLDVLKPWTLTFSFGRALQQSTLKAWAGKTENVAKAQATFLTRCKGNSDATLGKYTGGASGDSAASESLYEEGYKY", "output": "Fructose-bisphosphate aldolase that plays a key role in glycolysis and gluconeogenesis."}]}
+{"id": "function_test_645", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDPGTTGIVGGVSEAKPATPEIQEVADKVKRQLEEKTNEKYEKFKVVEYKSQVVAGQILFMKVDVGNGRFLHMKVLRGLSGDDDLKLLDYQTNKTKNDELTDF", "output": "This is an intracellular thiol proteinase inhibitor."}]}
+{"id": "function_test_646", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSSVMHYYPVHQAKVGSYSADPSEVKYSDLIYGHHHDVNPIGLPPNYNQMNSNPTTLNDHCSPQHVHQQHVSSDENLPSQPNHDSQRVKLKRSRTAFTSVQLVELENEFKSNMYLYRTRRIEIAQRLSLCERQVKIWFQNRRMKFKKDIQGHREPKSNAKLAQPQAEQSAHRGIVKRLMSYSQDPREGTAAAEKRPMMAVAPVNPKPDYQASQKMKTEASTNNGMCSSADLSEILEHLAQTTAAPQVSTATSSTGTSTNSASSSSSGHYSYNVDLVLQSIKQDLEAAAQAWSKSKSAPILATQSWHPSSQSQVPTSVHAAPSMNLSWGEPAAKSRKLSVNHMNPCVTSYNYPN", "output": "Required for the differentiation of the dorsal-ventral pattern, and does not appear to be involved in the process of segmentation."}]}
+{"id": "function_test_647", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSRLGFEQFPDYQVPGMKHPDFSPYESNGGSIVAIAGDDFAVIAADTRLSSGYNIHSRTQSKLFKLSPQTVLGSAGCWADTLSLTGSIKVRMQSYEHTHLRTMTTEAVAQMLSIAMYNRRFFPYYVSNILAGIDNEGKGVVYSYDPIGHCEKATYRAGGTAGTLLQPVLDNQIGHKNMNLEDADKIKLTKERAVSVASDTFISAAERDIYTGDSVLINIITKDGIEVRTLTLRQD", "output": "Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity."}]}
+{"id": "function_test_648", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MMRSFVSLISLLLLLSFSSSVLSTKKSSFQKLPVPGNRTGPEAFAFDSTGKGFYTGVTGGKILKYLPKKGYVDFAQITNSSKSSLCDGALGTTNVEKCGRPAGIAFNTKTGDLYVADAALGLHVIPRRGGLAKKIADSVGGKPFLFLDGLDVDPTTGVVYFTSFSSTFGPRDVLKAVATKDSTGKFFKYDPSKKVVTVLMEGLSGSAGCAVSSDGSFVLVGQFTKSNIKRYWIKGSKAGTSEDFTNSVSNPDNIKRIGSTGNFWVASVVNSATGPTNPSAVKVSSAGKVLQTIPLKDKFGDTLVSEVNEYKGQLYIGALFGPFAGILKL", "output": "Catalyzes the stereospecific condensation of tryptamine with secologanin to form strictosidine, the key intermediate of indole alkaloid biosynthesis."}]}
+{"id": "function_test_649", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEHQQLRKYVELYNKEVEEFYNGAASGRPAEFHPSKVHVKSIHEKAGTANAGVEISSVGVDWDSEEKNTFFWCLSRYSIHRVDEWRSLLPRKSAMEILGYYRLLRRASASARSRKAGDDGAPIAYEMSAEWVALETKLSETVMAITEGAAEVADEEGHCEGLIDYESWKRRWVAIYSHSRIAEIRPLPRHALPLSRSATQTLERCVSRYTRTLLWCTALAGMASRSVSARAAESRGHKSLPTVVTRRQVERALCTEARSRDLHVLPRRIVLTLRKWELDYPREGKLFRTKEMAHLFLQSQLSRRDAPPVHQDENQENQENQENQEQDNTASEGESEAERDEIDEADLFRSALHENQLLKWLSK", "output": "Component of the UAF (upstream activation factor) complex which interacts with the upstream element of the RNA polymerase I promoter and forms a stable preinitiation complex. Together with SPT15/TBP UAF seems to stimulate basal transcription to a fully activated level."}]}
+{"id": "function_test_650", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIFKRAVSTLIPPKVVSSKNIGSAPNAKRIANVVHFYKSLPQGPAPAIKANTRLARYKAKYFDGDNASGKPLWHFALGIIAFGYSMEYYFHLRHHKGAEEH", "output": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane."}]}
+{"id": "function_test_651", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "METDLNSQDRKDLDKFIKFFALKTVQVIVQARLGEKICTRSSSSPTGSDWFNLAIKDIPEVTHEAKKALAGQLPAVGRSMCVEISLKTSEGDSMELEIWCLEMNEKCDKEIKVSYAVYNRLSLLLKSLLAITRVTPAYRLSRKQGHEYVILYRIYFGDVQLNGLGEGFQTVRVGTVGTPVGTITLSCAYRINLAFMSTRHFERTPPIMGIIIDHFVDRPYPSSSPMHPCNYRTAGEDTGVACPSVEDSQEVCATSFSTSPPSQLMVPGKEGGVPLGPSQPAHAAQADQERLATYTPSDGAHCAATPSSSEDAETVSNSSEGRASPHDVLETIFVRKVGAFVNKPINQVTLTSLDIPFAMFAPKNLELEDADPMVNPPDSPETTSPLQGSLHSDGSSGGSSGHTQDDFVMIDFKPAFSKDDILPMDLGTFYREFQNPPQLSSLSLDIGAQSMAEDLDSLPEKLAAHEKNVREFDAFVETLQ", "output": "Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation."}]}
+{"id": "function_test_652", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSSRRSRSRQSGSSRITDEQISDLVSKLQDLLPEARLRSNDRVPSSRVLQETCNYIRSLHQEVDDLSERLSELLATSDMSSAQAAIIRSLLM", "output": "Atypical and probable non DNA-binding bHLH transcription factor that acts as a positive regulator of grain size. Binds the transcription repressor APG and forms a heterodimer of antagonistic bHLH transcription factors that regulates grain length and weight by controlling cell elongation in lemma and palea. May be involved in the control of lamina inclination through brassinosteroid signaling pathway."}]}
+{"id": "function_test_653", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQIITTTFIQKVILGSHQLHEQLSIVEARMIESAIVSMLTESFCENEQTLKYLARLLSPMSYMDVINARRGKKICGYPLCYKSAAENSSDGFFIHSMYCNNYHSKCSLYLMRQLSQTPLHERRGVHLTSYINLEFDDMYSVSLLEELVGSEVPIDTVKSLITSFKDLEFDDTYKNEPLPLDVYFGQLTTDEETCIE", "output": "Probable RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase that regulates RNA polymerase II transcription. May have functional redundancy with RTR1."}]}
+{"id": "function_test_654", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MMNFEVSTTKQIGVGLTTFGFFFIFLGVLMFLDSALLAIGNLLFIVGITFIIGVQRTLVFFFEFRKLKGSILFFGGILVVLFGYPLFGMIAECWGFIVLFGGFLPGIVNLLRSIPGISTITYLPGIRQVLDRLAPESKYPV", "output": "May be involved in fusion of ER-derived transport vesicles with the Golgi complex (By similarity). Involved in regulating AMsh glial cell size, acting by modulating the E3 ubiquitin ligase rnf-145/RNF145, probably by mediating the translocation of rnf-145 from the cis-Golgi to the trans-Golgi during development ."}]}
+{"id": "function_test_655", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAIPGRQYGLILPKKAQQLHPVLQKPSVFGNDSDDDDDETSVSESLQREAAKKQAMKQTKLEIQKALAEDSTVYEYDSIYDEMQKKKEESNPKLLLGKDRKPKYIHNLLKAVEIRKKEQEKRMEKKIQREREMEKGEFDDKEAFVTSAYKKKLQERAEEEERERRAAALEARLDVTKQRDLSGFYRHLLNQAVGEEEVPTCSFREARSEIKEEKSKGYSDEVSSESRIPPENCIRQTGVKVEENPDADSDFDAKSSENDEMEGDKGNCRREKGTETLSSHSKHHRNPARSPSSSEEREHGTQCHTKSSRSRGHEKREDEHQERPAREQDSYHTDRDSRKEKRDSHRHRESSHRDSHWKRHEEERLRGRDERERNDREWKREKDREKYPSREQERHRQRNNYDRHNEKGCEKEEKSKEKEEHVKARKERYENSDKYRDREKREVSVESSERNRDRKESSPNSRAKDRFVNQERASKMRDMEKDKERNPEKPSSSEASLGAKHRITEECQETGKEQERLHETVNKFAKRSNEETVTSARDRYLARQMARINAKTYIEKEDD", "output": "RNA-binding protein that mediates pre-mRNA alternative splicing regulation."}]}
+{"id": "function_test_656", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDSGDIEEAGGNGEEEFRSGPRLGGSKYRPVVAHDRAVVEMSSIDPGSSSSTLKNIKVVAPGDVGAGVRGPEDGVNGHQKESKLELFGFDSLVNILGLKSMTGEQIQAPSSPRDGEDISITQGHPKPPALKMGTMMGVFVPCLQNILGIIYYIRFTWIVGMAGIGQGLVLVFLCGLCTFLTTISLSAIATNGAMKGGGPYYLIGRALGPEVGISIGLCFFLGNAVAGALYVLGAVETFLKAFPAAGIFRETITKVNGTAVSESIQSPNSHDLQVYGIVVTILLCFIVFGGVKMINRVAPAFLVPVLLSIFCIFIGIFLAKTDDPDNGITGLRLKSFKDNWGSAYQMTNDAGIPDPTGGTYWSFNELVGLFFPAVTGIMAGSNRSASLKDTQKSIPVGTLAATLTTTSLYLISVLFFGAVATRDKLLTDRLLTATIAWPFPAIVHVGIILSTLGAALQSLTGAPRLLAAIANDDILPILNYFKVADTSEPHIATLFTAFICIGCVVIGNLDLITPTVTMFYLLCYSGVNLSCFLLDLLDAPSWRPRWKYHHWSLSFVGASLCIVIMFLISWSFTVVAIALASLIYKYVGLKGKAGDWGDGFKSAYFQLALRSLRSLGANQVHPKNWYPIPLVFCRPWGQLPENVPCHPKLADFANCMKKKGRGMSIFVSILDGDYYECAEEAKEACKQLATYIEYKRCEGVAEIVVAPNMTEGFRGIIQTMGLGNLKPNIVVMRYPEIWRRENLTEIPSTFVGIINDCITANKAVVIIKGLDEWPNEYQRQYGTIDLYWIVRDGGLMLLLSQLLLTKESFESCKIQLFCIAEEDSDAEALKADVKKFLYDLRMHAEVIVVTMKSWDIRSEGNSQEDSLEAFDAAQRRISDYLGEIKRQGSNPLLANGKPMVVNEQQVEKFLYTMLKLNSTILSYSRMAAVVLVSLPPPPLNHPAYFYMEYMDLLVENVPRMLIVRGYHRDVVTLFT", "output": "Cation/chloride cotransporter that mediates potassium-chloride and sodium-chloride cotransports. Involved in plant development and Cl(-) homeostasis. May be involved in long distance Cl(-) transport. Does not function as an H(+)-dependent cotransporter."}]}
+{"id": "function_test_657", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAAEEGQVIGCHTNDVWTVQLDKAKESNKLIVIDFTASWCPPCRMIAPIFNDLAKKFMSSAIFFKVDVDELQSVAKEFGVEAMPTFVFIKAGEVVDKLVGANKEDLQAKIVKHTGVTTA", "output": "Thiol-disulfide oxidoreductase probably involved in the redox regulation of a number of cytosolic enzymes. Possesses insulin disulfide bonds reducing activity."}]}
+{"id": "function_test_658", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAGNFWQSSHYLQWILDKQDLLKERQKDLKFLSEEEYWKLQIFFTNVIQALGEHLKLRQQVIATATVYFKRFYARYSLKSIDPVLMAPTCVFLASKVEEFGVVSNTRLIAATTSVLKTRFSYAFPKEFPYRMNHILECEFYLLELMDCCLIVYHPYRPLLQYVQDMGQEDVLLPLAWRIVNDTYRTDLCLLYPPFMIALACLHVACVVQQKDARQWFAELSVDMEKILEIIRVILKLYEQWKNFDERKEMATILSKMPKPKPPPNSEGEQGPNGSQNSSYSQS", "output": "Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex (By similarity)."}]}
+{"id": "function_test_659", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEQHEEAAERKPSPPVIFRLFGVEVRGGGGGVDEEEYEEEEVEGGLFIKKSSSMPNLTSIDPLPVPADGGKRRASDDSELASGQQKRRRRKVQERKKGVPWTEEEHKKFLEGLRQLGKGDWRGISKNFVTSRTATQVASHAQKYFLRQTNPGKKKRRASLFDVVAECSDDQLPSPQSVGTKPPTQDIIHTDRGDVPILSYPVARGFRGDSVQVDELTEYVKRLKAAEDMSLSMISGLEMASSSISSLELSIAPPHCAIEAAIKVL", "output": "Transcription activator that binds to 5'-TATCCA-3' elements in gene promoters. Derepresses weakly the sugar-repressed transcription of promoters containing SRS. Contributes to the sugar-repressed transcription of promoters containing 5'-TATCCA-3' elements."}]}
+{"id": "function_test_660", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSRQTATALPTGTSKCPPSQRVPTLSGTTASNSDLASLFECPVCFDYVLPPILQCQSGHLVCSNCRPKLTCCPTCRGPLGSIRNLAMEKVANSVLFPCKYASSGCEVTLPHTDKAEHEELCEFRPYSCPCPGASCKWQGSLDAVMPHLLHQHKSITTLQGEDIVFLATDINLPGAVDWVMMQSCFGFHFMLVLEKQEKYDGHQQFFAIVQLIGTRKQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSDCLVFDTSIAQLFAENGNLGINVTISMC", "output": "E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It probably triggers the ubiquitin-mediated degradation of different substrates."}]}
+{"id": "function_test_661", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNSSTSAGVYANGNDNKKFKGDRPPCSPSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMINYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGATANEGTLLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAQYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIMSSPYAGAAGFAPAIAFPQAAGLSVPAVPGALGPLTLTSSAVSGRMAIPGASGMPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI", "output": "RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes Fas exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U) (By similarity)."}]}
+{"id": "function_test_662", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAYHSAYGVHGSKHRTRAAPDPPPLFDDTSGGYSSQLGGYPAPGADVAFSVNNLLGDPVANMAMAYGTSIASQGKDIVHKELHRFVSVNKLKYFFAVDTAYVAKKLGLLVFPYTHQNWKMQYSHDVPLPPRKDLNAPDLYIPTMAFITYVLLAGMALGIQQRFSPEVLGLCASTALVWVFMEVLALLLGLYLATVRSELSTFHLLAYSGYKYVGMILSVLTGLLFGSDGYYVALAWTSSALMYFIVRSLRTAASGPDSMGGPAPRQRLQLYLTLGAAAFQPLIIYWLTFHLVR", "output": "Possible role in transport between endoplasmic reticulum and Golgi."}]}
+{"id": "function_test_663", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDIKFEGNDAECTAGLKKASEGSFVLKDHVLIEFKINGKVAGKIKTPCEGVVTFGKGLKPGIVLNKGQVIATVSECTHAIVIKDMCATCGKDLREKGGRAGQRKEQSTANVSMIHHVPELIVSDTLAKEIGSADENNLITNRKLVLLVDLDQTIIHTSDKPMTVDTENHKDITKYNLHSRVYTTKLRPHTTEFLNKMSNMYEMHIVTYGQRQYAHRIAQILDPDARLFEQRILSRDELFSAQHKTNNLKALFPCGDNLVVIIDDRSDVWMYSEALIQIKPYRFFKEVGDINAPKNSKEQMPVQIEDDAHEDKVLEEIERVLTNIHDKYYEKHDLRGSEEVLLDVKEVIKEERHKVLDGCVIVFSGIVPMGEKLERTDIYRLCTQFGAVIVPDVTDDVTHVVGARYGTQKVYQANRLNKFVVTVQWVYACVEKWLKADENLFQLTKESTPPVGRPLGSKYVNDLANMDTIGKAALADMNNEVDEALSDDEDDGDNEDEDDDGNDVGEDKGDENLEEKQEKNEEEMDDVEQNGSVENQSGDALENETDSTSRGQKRKHCPEMEDEEEESDSDNEDDDTPMSYKALLSDSRKKGRIVPENEDDAVFDVDDEKGHAPANIDEEEDDEDNEDEEVPESDDDDEFEDMAALIERQISDAVDEKDQ", "output": "During the late stages of oogenesis, dephosphorylates 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit ama-1 . Similarly, dephosphorylates 'Ser-5' of ama-1 in early embryonic cells prior to the activation of the zygotic transcription program at the 4-cell embryonic stage . May dephosphorylate 'Ser-2' of the ama-1 heptad repeats YSPTSPS in embryonic somatic and germline cells ."}]}
+{"id": "function_test_664", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDLVIGGKFKLGKKIGSGSFGELYLGVNVQTGEEVAVKLENVKTKHPQLHYESKLYMLLQGGSGIPNIKWFGVEGDYSVMVIDLLGPSLEDLFNYCNRKLTLKTVLMLADQLLNRVEFMHTRGFLHRDIKPDNFLMGLGRKANQVYIIDFGLGKKYRDLQTHKHIPYRENKNLTGTARYASVNTHLGVEQSRRDDLESLGYVLMYFLKGSLPWQGLKAGTKKQKYDRISEKKVSTPIEVLCKNQPSEFVSYFHYCRSLRFDDKPDYSYLKRLFRDLFIREGYQFDYVFDWTVLKYPQIGSSSGSSSRTRHHTTAKPGFNADPIERQERILGKETTRYKIPGAVEAFSRRHPTTTSSPRDRSRSRNSDDGPFSKQTHGDSERANSSSRYRASSSRKAVAASSSRPSSAGGPSESRTSSRLVSSSGGGGSGSGNGRPSTSQRVQAGYESKTLSFSRATAARNTREDQLRSFELLSLRK", "output": "Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins."}]}
+{"id": "function_test_665", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLGKGGKRKFDEHEDGLEGKIVSPSDGPSRVSYTLQRQTIFNISLMKLYNHRPLTEPSLQKTVLINNMLRRIQEELKQEGSLRPAFTPSSQPSNSLSDSYQEAPPPAPHPCDLGSTTPLEACLTPASLLEDDNDDTFCTLQAVHPAAPTRLSSAALPAEKDSFSSALDEIEELCPTSTSTEAAHTAAPEGPKGTSSESSVQKPEGPEEGRTDDSRFMDSLPGNFEITTSTGFLTDLTLDDILFADIDTSMYDFDPCTSASGTASKMAPVSADDLLKTLAPYSNQPVAPSQPFKMDLTELDHIMEVLVGS", "output": "Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. May act as coactivator as well as corepressor of E2F1-TFDP1 and E2F4-TFDP1 complexes on E2F consensus binding sites, which would activate or inhibit E2F-target genes expression. Modulates fat storage by down-regulating the expression of key genes involved in adipocyte lipolysis, thermogenesis and oxidative metabolism."}]}
+{"id": "function_test_666", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEKLSNGVRDHCLISDYVSPSAPAPLKQPFVIGVAGGTASGKTTVCNMIMSQLHDQRVVLVNQDSFYHSLTKEKLNKVHEYNFDHPDAFNTEVLLSCMEKLRSGQPVNIPSYDFKIHQSIESSSPVNPGDVIILEGILVLNDPRVRDLMNMKIFVDTDADVRLSRRIQRDTVERGRNIQNVLEQYTKFVKPSFDEYIQPSMKYADIIIPRGGDNDVAIDLIVQHIRTKLCQHNLCKIYSNIFIISSTFQIKGMHTLIRDINTTKHDFVFYADRLIRLVVEHGLGHLPFTEKQITTPTGSVYTGVDFCKRLCGVSVIRSGESMENALRACCNGIKIGKILIHRENNDGRQLIYEKLPKDISSRHVFLLDPVLASGYSAVKAITLLLSKGVPESHIIFLNLIAAPQGIHALCKKFPMLKIVTSEIDSSLNEDSRVIPGLGEFADRYFGTNNINSKVSSLSTNLKLRS", "output": "Involved in the pyrimidine salvage pathway."}]}
+{"id": "function_test_667", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MESIWRIATGQDPSREDYEGIEFWSNPERSGWLTKQGDYIKTWRRRWFVLKRGKLLWFKDQAAAGIRGSTPRGVISVGDCLTVKGAEDVVNKPFAFELSSGSYTMFFIADNEKEKEEWINSIGRSIVQHSRSVTDSEVLDYDHRR", "output": "Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides."}]}
+{"id": "function_test_668", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MASKNSASLALFFALNILFFTLTAGTNCRCNPSPKPRPLPNPKVPSPKVPTPSVPSPYVPTPSVPSPSVPTPSVPSPSVPSPNPTPVIPPRTPGSSGNCPIDALRLGVCANVLSGLLNVQLGQPSPQPCCSLIQGLVDLDAAVCLCTALRANVLGINLNVPISLSVLLNVCNRRLPSNFQCA", "output": "Probable lipid transfer protein (LTP). May improve freezing survival. Seems to control the flowering process and lignin synthesis. Confers resistance to Botrytis cinerea."}]}
+{"id": "function_test_669", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDDPSATLLPEHSEDLRLARDAELKKVLKLKLVLDELRRLDVGPNPSDEIKRALKLVSIGSYARLGEMEGAGQEQVLGLPSGSSFPPLNYTDRKTVRTKLSAQLRTTLQPIAELCDRIREEFPDAFGQEADLSCDQKEILRLEEEHRSGLEKLVALLTRKCTLLKETAELKLGPQLANELKLQQAQAQLVQTKAELLRGFFVHEAASRTEHSVKAHKEVEAHLDELLAAKK", "output": "As part of the augmin complex, plays a role in centrosome-independent generation of spindle microtubules . The complex is required for mitotic spindle assembly through its involvement in localizing gamma-tubulin to spindle microtubules . dgt2 binds to microtubules in vitro ."}]}
+{"id": "function_test_670", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGENDESEIIEHHDDEEMEKRRPPRTHAQSFLESVASSVKEGHSSTQSSHRLLAYSDALISIIATVMILPVAHTKIQEDEELKQSIQALLTTKIAVYLMTFLIVTVAWAAHIRLFQVIERIDDTLALLNLACMMLITFLPYTFSLMATFPNNILGILLFCACVMVIGLIQALIVLYGFSHPFLLNDQIQMSENQAYYKQHILKVIMRVPIMCLFASIFSFIFFQLSYVLLAIVIFLPYISQCLKWIRSKAIGGQTDESPDSMPFYTYHPSEPLSKERVEAFSDGVFAIVATLLILDICEGNVPDPSVVKKKFDNSLIAALQEYGPEYLAYFGSFVTVGLLWFVHHSLFLHVTKATRLMGLFNTFSLAFVGGLPLAYQLTHESPRGSRNELEAVQISCVIIFFASLFQLAIWVTALFTERETLHPYVRYGGREHTFMLAKLSLYPCVALGTFFITCILSRFSAPIFHMMEICIPFAFLLLRLLVRVALALLRWLFCSARNDLERIPVEEEESRLPINDIVT", "output": "Proton-activated proton channel that catalyzes proton efflux from endosomes and lysosomes to maintain a steady-state pH. Activated at low pH (under pH 4.6) by luminal side protons: selectively mediates lysosomal proton release from lysosomes, eliciting a proton leak that balances V-ATPase activity to maintain pH homeostasis. Regulation of lumenal pH stability is required for autophagosome-lysosome fusion. May also act as a potassium channel at higher pH, regulating potassium conductance in endosomes and lysosomes. The potassium channel activity is however unclear as it was tested in non-physiological conditions for a lysosomal channel."}]}
+{"id": "function_test_671", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDKFLNNRWAVKIIALLFALLLYVAVNSNQAPTPKKPGESFFPTSTTDEATLTDIPVKAYYDDENYVVTGVPQTVNVTIKGSTSAVKKARQTKNFEIYADMEHLKTGTHKVELKAKNVSDGLTISINPSVTTVTIQERTTKSFPVEVEYYNKSKMKKGYSPEQPIVSPKNVQITGSKNVIDNISLVKASVNLENADETIEKEAKVTVYDKDGNALPVDVEPSVIKITVPVTSPSKKVPFKIERTGSLPDGVSIANIESSPSEVTVYGSQDVLDSLEFIDGVSLDLSKINKDSDIEADIPLPDGVKKISPSKVTLHIEVDSEADQKFENVPIKTVGLSSSQNIEFLDPESQAIDVTAKGSPTNINKLKKSDIELYVNVSDLEDGEHSVKLEVNGPQNVTWSLGRKNAKIKLTSKKSNTSTNDNSSNTSGNQDTDKQTNDQKNNQQEDTKNTDKNNNDQNQDGNKDQNQDQDEDESTANSQSSSE", "output": "Upon coexpression in E.coli stimulates the diadenylate cyclase activity of CdaA about 20-fold . In B.subtilis c-di-AMP is a second messenger that mediates growth, DNA repair and cell wall homeostasis; it is toxic when present in excess ."}]}
+{"id": "function_test_672", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MYGQCNIESDYALLESITRHLLGGGGENELRLNESTPSSCFTESWGGLPLKENDSEDMLVYGLLKDAFHFDTSSSDLSCLFDFPAVKVEPTENFTAMEEKPKKAIPVTETAVKAKHYRGVRQRPWGKFAAEIRDPAKNGARVWLGTFETAEDAALAYDIAAFRMRGSRALLNFPLRVNSGEPDPVRITSKRSSSSSSSSSSSTSSSENGKLKRRRKAENLTSEVVQVKCEVGDETRVDELLVS", "output": "Acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways. Involved in disease resistance pathways."}]}
+{"id": "function_test_673", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEGPRSDVGRWGRSPWQPTTPSPEPEPEPEPDRSSRSRRGGGRSFWARCCGCCSCGNRADDDWGPEPSGSRSRGTSSRGGGSRGGDSRGRDSRGGRRPESRGSGVNAAGDGTIREGMLVVNGVDLLCSRSDQNRREHHTDEFEYDELILRRGQPFHIILFLNREYESSDRIALELLIGNNPEVGKGTHVIIPVGKGGSGGWKAQVTKTNGHNLTLRVHTSPNAIIGKFQFTVRTRSEAGEFQLPFDPRNEIYILFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNYGQFDHGVLDACLYILDRRGMPYGGRGDPVSVSRVVSAMVNSLDDNGVLIGNWTGDYSRGTNPSAWVGSVEILLSYLRTGYSVPYGQCWVFAGVTTTVLRCLGLATRTVTNFNSAHDTDTSLTMDIYFDENMKPLEHLNHDSVWNFHVWNDCWMKRPDLPSGFDGWQVVDATPQETSSGIFCCGPCSVESIKNGLVYMKYDTPFIFAEVNSDKVYWQRQDDGSFKIVYVEEKAIGTLIVTKAINSNMREDITHIYKHPEGSEAERKAVEKAAAHGSKPNVYATRDSAEDVAMQVEAQDAVMGQDLTVSVVLTNRGSSRRTVKLHLYLCVTYYTGVSGPTFKETKKEVVLAPGASDTVAMPVAYKEYKPHLVDQGAMLLNVSGHVKESGQVLAKQHTFRLRTPDLSLTLLGAAVVGQECEVQIVFKNPLPITLTNVVFRLEGSGLQRPKVLNVGDIGGNETVTLRQTFVPVRPGPRQLIASLDSPQLSQVHGVIQVDVAPSSGGRGFSEAVGDSRSGENIPMAFRGGA", "output": "Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Responsible for cross-linking epidermal proteins during formation of the stratum corneum. Involved in cell proliferation (By similarity)."}]}
+{"id": "function_test_674", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLCSVIQRQTREVSNTMSLDSYYLGFDLSTQQLKCLAINQDLKIVHSETVEFEKDLPHYHTKKGVYIHGDTIECPVAMWLEALDLVLSKYREAKFPLNKVMAVSGSCQQHGSVYWSSQAESLLEQLNKKPEKDLLHYVSSVAFARQTAPNWQDHSTAKQCQEFEECIGGPEKMAQLTGSRAHFRFTGPQILKIAQLEPEAYEKTKTISLVSNFLTSILVGHLVELEEADACGMNLYDIRERKFSDELLHLIDSSSKDKTIRQKLMRAPMKNLIAGTICKYFIEKYGFNTNCKVSPMTGDNLATICSLPLRKNDVLVSLGTSTTVLLVTDKYHPSPNYHLFIHPTLPNHYMGMICYCNGSLARERIRDELNKERENNYEKTNDWTLFNQAVLDDSESSENELGVYFPLGEIVPSVKAINKRVIFNPKTGMIEREVAKFKDKRHDAKNIVESQALSCRVRISPLLSDSNASSQQRLNEDTIVKFDYDESPLRDYLNKRPERTFFVGGASKNDAIVKKFAQVIGATKGNFRLETPNSCALGGCYKAMWSLLYDSNKIAVPFDKFLNDNFPWHVMESISDVDNENWDRYNSKIVPLSELEKTLI", "output": "Xylulose kinase necessary for growth in culture media with D-xylulose as the solecarbon source."}]}
+{"id": "function_test_675", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTHVCSVILIRRSFDIYHEQQKISLHNESILLLEKNLADDFAFCSPDTRRLDIDELTVCHYLQNIRQLPRNLGLHSKDRLLINQSPPMPLVTAIFDSFNESGVNSPILSNMLYLSCLSMFSHKKELIPLLFNSISTVSGKVERLISFDIAKRWYLRDIAERMYTSESLIKKKLQDENTCFSKILLASRMSMARRLLELRQIPLHTIAEKCGYSSTSYFINTFRQYYGVTPHQFAQHSPGTFS", "output": "Depending on the conditions (growth phase and medium), acts as a positive or negative regulator of gadA and gadBC. Repression occurs directly or via the repression of the expression of gadX. Activation occurs directly by the binding of GadW to the gadA and gadBC promoters."}]}
+{"id": "function_test_676", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDEKRIFIRLLECDDPDLFNWLMNHGKPADAELEMMVRLIQTRNRERGPVAI", "output": "An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins . Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH . Required for flavinylation of the flavoprotein subunit FdrA of fumarate reductase (FDR) . Binds 2 different sites on the flavoprotein target FrdA (and presumably also SdhA), possibly positioning FAD and protein to facilitate the covalent bond formation; covalent attachment of FAD is not required for SDH or FDR complex enzyme formation . Overexpression of this protein and YgfX (formerly cptA) restores production of prodigiosin antibiotic (Pig) in Serratia strains with deletions of sdhE-ygfX ."}]}
+{"id": "function_test_677", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAGGEAGVTLGQPHLSRQDLATLDVTKLTPLSHEVISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPPRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKPTVDDD", "output": "As a subunit of eukaryotic initiation factor 2 (eIF-2), involved in the early steps of protein synthesis. In the presence of GTP, eIF-2 forms a ternary complex with initiator tRNA Met-tRNAi and then recruits the 40S ribosomal complex and initiation factors eIF-1, eIF-1A and eIF-3 to form the 43S pre-initiation complex (43S PIC), a step that determines the rate of protein translation. The 43S PIC binds to mRNA and scans downstream to the initiation codon, where it forms a 48S initiation complex by codon-anticodon base pairing. This leads to the displacement of eIF-1 to allow GTPase-activating protein (GAP) eIF-5-mediated hydrolysis of eIF2-bound GTP. Hydrolysis of GTP and release of Pi, which makes GTP hydrolysis irreversible, causes the release of the eIF-2-GDP binary complex from the 40S subunit, an event that is essential for the subsequent joining of the 60S ribosomal subunit to form an elongation-competent 80S ribosome. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must be exchanged with GTP by way of a reaction catalyzed by GDP-GTP exchange factor (GEF) eIF-2B (By similarity). Along with its paralog on chromosome Y, may contribute to spermatogenesis up to the round spermatid stage (By similarity)."}]}
+{"id": "function_test_678", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MMSSAPETFSLDHLSQHQQQQPPPLAEQEQLCYVHCNFCDTILAVGVPCSSLFKTVTVRCGHCANLLSVNLRGLLLPAAASTANQLPFGQALLSPTSPHGLLDEVPSFQAPASLMTEQASPNVSSITSSNSSCANNAPATSMASAANKATQREPQQPKNAPSANRTSEKRQRVPSAYNRFIKDEIQRIKASNPDITHREAFSAAAKNWAHFPHIHFGLMPDQGLKKTGIQSQDGAGECMLFKDGLYAAAAAAAAATAASSMGVTPF", "output": "May be involved in leaf cell growth and differentiation, rather than abaxial cell fate determination."}]}
+{"id": "function_test_679", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPAAGSEPSRPPSPPGVQEQSAEPRPPPPPHGELQYLGQIEHILRCGFRRDDRTGTGTLSVFGMQARYNLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDGLGFSDRAEGDLGPVYGFQWRHFGAEYKDMDSEYSGQGVDQLQKVIDTIKTNPNDRRIILCAWNPKDLPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITDLKPGDFVHTLGDAHIYLNHIEPLKTQALMELRGQSSRSLDGDGQAGTSRWAPVATDTERDRCCELQREPRPFPKLKILRKVETIDDFQAEDFQIEGYNPNPTIKMEMAV", "output": "Catalyzes the reductive methylation of 2'-deoxyuridine 5'-monophosphate (dUMP) to thymidine 5'-monophosphate (dTMP), using the cosubstrate, 5,10- methylenetetrahydrofolate (CH2H4folate) as a 1-carbon donor and reductant and contributes to the de novo mitochondrial thymidylate biosynthesis pathway."}]}
+{"id": "function_test_680", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSFCSFFGGEVFQNHFEPGVYVCAKCGYELFSSRSKYAHSSPWPAFTETIHEDSVAKCPEKNRPEALKVSCGKCGNGLGHEFLNDGPKRGQSRFUIFSSSLKFIPKGKEAPASQGD", "output": "Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (MICAL1, MICAL2 or MICAL3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to actin repolymerization in macrophages."}]}
+{"id": "function_test_681", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSHHLFLPVVIMVVSPIPPGAFQDSVVSPTQGEFEDLDCGDCGRPEPSSRIVGGSDAHPGTWPWQVSLHQGGGHICGGSLIAPSWVLSAAHCFVTNGTLEPADELSVLLGVHSQDGPLEGAHMRSVATILIPDNYSTVELGADLALLRLASPAKLGPSVRGADLALLRLASPAKLGPSVRPVCLPRASHLFAHGTACWATGWGDVQEAVPLPLPWVLQEVELRLLGEAACQCLYSRPGPFNLTFQLLPGMLCAGYPAGRRDTCQGDSGGPLVCEDGGRWFLAGITSFGFGCGRRNRPGVFTAVAPYESWIREHVMGSEPGPVFPSQLQKPQSGPWEPREENCTFAQPECGKAPRPGTWPWEAQVTVPGSTPCYGALVSDRWVLAPASCFLDSPHDFETWRVLLPSRPEEERVARLVAHENASRDFASDLALLQLRTRVNLTAAPSAVCLPHHEHYFLPGSHCRLARWGRGELAPGSSAQLEAQLLNGWWCHCLYGRQGETVPRPGDPPHLLCPAYQEEEEAGLCWVDSSWSLLCREEGTWFLAGYRTLSDGCLRPRAFSPMQTHGPWIRHVTQGAYLEDQLTWDWGPEGEETEKQTCPTHTEHGACGLRPKSTPAGVLWPWLTEVHVTGDRVCTGILVAPGWVLAATHCILRLGSTTVPYIEVYLGRAGVSSLPQGHQVSRSVVSIRLPRHLGLRPPLALLELNSRVEPSPSALPICLHPGGIPSGASCWVLGWKNPQDRVPVVAAVSILTPRLCHCLYPGILTPGTFCVLYSEGQEDRCEVTSAPPLLCQTEEGPWVLVGMAVRGNRELFAAIGPEATWISQTVGEAHFLHLGGSSYWSPEGSDLCPQDLAGSASSPKVTALLLLLLLAPLIPR", "output": "Serine protease. Hydrolyzes the peptides N-t-Boc-Gln-Ala-Arg-AMC and N-t-Boc-Gln-Gly-Arg-AMC and, to a lesser extent, N-t-Boc-Ala-Phe-Lys-AMC and N-t-Boc-Val-Leu-Lys-AMC. Has a preference for substrates with an Arg instead of a Lys residue in position P1 (By similarity)."}]}
+{"id": "function_test_682", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPVRQKDAQRALQLLEEYQTKLSQTGDPHLRLSIERVINIFKSTLFQALVDIQEYYEVSLQDTEDKPIEDSSLKSRESFPPVNEWNLSVPPSTTGPTEPVPINLPQTEEKYRYQDEDTTSPPEHSSPHIPGDARPPELVQVSEKNISQIENVHGYVSHSHISPMKQADVIPPPSAPIIPVIPISPVPAETTAIIPAPASQASPAPVVVNTESLDSSPYVNGTEADYEYEEITLERGNSGLGFSIAGGTDNPHIGEDPSIFITKIIPGGAAAQDGRLRVNDCILRVNDVDVRDVTHSNAVEALKEAGCIVRLYVRRRKPLSEKIMDVKLVKGPKGLGFSIAGGVGNQHIPGDNSIYITKIIEGGAAHKDGRLQIGDKLLAVNAVCLEEVTHEDAVAALKNTPDVVYLKVAKPTSVFMNDSYAPPDVTSSYSQHMENHISTQSYLSQPLTPATPSRYSPVSKGMLGDDEITREPRKIVLHRGTTGLGFNIVGGEDGEGIFISFILAGGPADLCGELRKGDRIVSVNGVDLRSATHEQAAAALKNAGQTVTIIAQYRPEEYSRFEAKIHDLREQMMNSSISSGSGSLRTSQKRTLYVRALFDYDITKTVKFNSKSRDKASLNDKRRKTLFSRKFLFSKNKDSGEQDTSDVDQHVTSNASDSESSFRGQEDYVLSYETVTQQEVSYSRPVIILGPMKDRINDDLISEFPDKFGSCVPHTTRPKRDYEVDGRDYHFVNSREQMEKDIQDHKFIEAGQYNNHLYGTSVQSVREVAEKGKHCILDVSGNAIKRLQLAQLYPIAVFIKPKSVENILEMNKRLMEEQGRKTYDRAMKLEQEFLEHFTAIVQGDTLEEIYNQVKQIIEEQSGPFIWVPVKEKL", "output": "Essential multidomain scaffolding protein required for normal development. Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. May play a role in adherens junction assembly, signal transduction and cell proliferation (By similarity). May play a role in synapse assembly and function."}]}
+{"id": "function_test_683", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MWLELGAMLRTTCGPLGRAVRLPCAGALRLRPHWWGPCRDCLAQRVHQDQPGRGLTEDEIRRAREARLRKAPRPQLSDRSRERKVPASRISRLASFGGLAVGLGLGALAEVTKKSLPGGSLQHEGSSPFLTEANAERIVQTLCTVRGAALKIGQMLSIQDNSLISPQLQRVFERVRQSADFMPRWQMMKVLEEELGKDWQDKVASLEEVPFAAASIGQVHQGVLKDGTEVAVKIQYPGVAESIQSDVQNLLALLKMSVGLPEGLFAEQSLQTLQQELAWECDYRREAACAQTFKKLLADDPFFRVPAVVEELCTTRVLGMELAGGIPLDQCQGLSQDIRNQICFQLLRLCLRELFEFRFMQTDPNWANFLYDASSHKVTLLDFGASRAFGTEFTDHYIEVVKAAADGDRDRVLQKSQDLKFLTGFETKAFSDAHVEAVMILGEPFAASGSYDFGAGETARRIQGLIPVLLRHRLRPPPEETYALHRKLAGAFLACARLHAHIACRDLFQDTYHRYWASRQTLPLPAAS", "output": "Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is unclear: does not show any protein kinase activity. Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway. Required for podocyte migration."}]}
+{"id": "function_test_684", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MADLGLQKGKRVLLIWTQPSSSSALKQFAESIAAVVGDQSLVSLENSERLLLSSHNASSYDCVLSGLLTDSSLIHSSEMLVEMARVMKPGGTLVLEEPVTGSEDTGVRTAEKLMSAIKLAGLVSVTEVKTEPLSPKAAAALTERTGFSGNTLSRVRMTASKPDFEVGSSTQLKLSFGKKKTTTVKPALDPGTAQKWTLSANDMDDDDVDLVDSDALLDADDLKKPDPSSLKASCGDDSKKKKKACKNCTCGLAEELEQESKAAQKASQPKSACGNCYLGDAFRCGSCPYLGMPAFKPGEKVLLANTDIADK", "output": "Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells."}]}
+{"id": "function_test_685", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRGSFFSRLPPQLSLLLLLLLLLSWRRVWTQEHIGTDPSKSPVAPVCPEACSCSPGGKANCSALALPAVPAGLSWQVRSLLLDRNRVSTLPPGAFADAGALLYLVLRENRLRSVHARAFWGLGVLQRLDLSSNQLETLSPGTFTPLRALSFLSLAGNRLALLEPSILGPLPLLRVLSLQDNSLSALEAGLLNSLPALDVLRLHGNPWACSCALRPLCTWLRKHPRPTSETETLLCVSPKLQTLNLLTDFPDNAFKQCTQSLAARDLAVVYALGPASFLASLAICLALGSVLTACGARRRRRRTTVRHLIRRQPDPEGPASLEDVGSPTTTAIQA", "output": "Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Required for the conversion of BK alpha channels from a high-voltage to a low-voltage activated channel type in non-excitable cells. These are characterized by negative membrane voltages and constant low levels of calcium (By similarity)."}]}
+{"id": "function_test_686", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MALSFVFITCFMILLDTSQSCHTPDDFVAITSPGHIMIGGLFAIHEKMLSSDDHPRQPQIQKCVGFEISVFLQTLAMIHSIEMINNSSLLSGVKLGYEIYDTCTEVTAAMAATLRFLSKFNCSRETVIFQCDYSSYVPRVKAIIGAGYSEISMAVSRMLNLQLMPQVSYESTAEILSDKIRFPSFLRTVPSDFYQTKAMAHLIRQSGWNWVGAITTDDDYGRLALNTFAIQAAENNVCIAFKEVLPAFLSDNTIEVRINQTLEKIIAEAQVNVIVVFLRKFHVFNLFNKAIERKISKIWIASDNWSTAAKIITIPNVKKLGKVVGFTFRRGNMSSFHSFLQTLHMYPSDNNKPLHEFAMLFSACKHIKDGDLSQCISNYSQATWTYDTTKTIETHLFKRNDFLWHYTEPGLIHSIQLAVLALGHAIRDLCQDRDCQKPNAFQPWELLAVLKNVTFTDGKNSFHFDAHGDLNTGYEVVLWKETNGLMTVTKMAEYDLQHDVFITTNQETKHEFRKLKQILSKCSKECIPGQMKKATGSQHSCCYECVNCPENHYSNETDMDHCLVCNNETHWAPVRSTMCFEKEVEYLDWDDSLALLLIALSLLGIAFVLAVGIIFTRNLKTPVVKSSGGLVVCYVMLACHALNFASTGFFIGEPQDFTCKTRQTLFGVSFTLCVSCILTKSLKILLAFSFDPTLKTFLKCLYRPVPIVLTCTGIQVVICTLWLVLAAPTVEENTSLPRVIILECEEGSALAFGTMLGYIAVLAFICFVFAFKGRKLPENYNEAKFLTFGMLIYFIAWITFIPVYATTFGKYLPAVEIIVILISNYGILCCTFFPKCYIILCKQKTNTKSVFLQMVYNYSAHSVDSLALSHVSLDSASHSTATTNPRPGNKTAACQNYKHLPVQVLAHTGMEKTMHASKTLHQKRSSSI", "output": "Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is augmented by divalent cations Ca(2+) and Mg(2+). Activated by extracellular calcium and osteocalcin. Seems to act through a G(q)/G(11) and G(i)-coupled pathway. Mediates the non-genomic effects of androgens in multiple tissue. May coordinate nutritional and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalent ions and its responsiveness to anabolic steroids (By similarity)."}]}
+{"id": "function_test_687", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "METETEHDRTVSVDDNDSLVPEPSSTKESFFEDLSLTGQVMNPQLSSAGEVLTKVELDFAFVSEKLVNLSLLTMQLGTRENDFESFVSKKEEDEEEPSSNVDDDDDSAEKALEFDLLSSILNSEVKELESLLGFLQNEIQSARVMISPFQHDGEAFLDLEGKLNDTEQSLGQLMEQVVEMKKQSSNFQRLSSGLDEQGSWSGGQTSVSQNDGEFGDLSAKINMQTADQQRNVLRMLEKSLAKEMELEKKLSESRNTERELEMKLYSSEQDVVYMEEVTEDAFSRWLEADNAAEVFKGTSKEMSGKLQILQFNLSGSFKREDNLKSKLVDSKERLEAKECALHKLDSSNARLADFLVAQTEGLKESLQEAEEKLILLNTENSTLSEKVSSLEEQLNEYGIQTEDADATSGALITDLERINEELKDKLAKTEARAEETESKCKILEESKKELQDELGNFRDKGFTIHKLASLEKHLRDSDLQLEHAVAAVEASKEKQNLLYSTVSDMEDVIEDLKSKVLKAENRADITEEKLIMVSESNAEVNEELKFFKGRLKEGEKYLQQAEERKLRTAKDIGVHNKIMKKLVMQLAAERERLHKQITNLSRENCVLMVKLKKVGKTGYMESGNGSEVSPKSDQNASSCHQGSRLQATFISLTNPEEEETGSKSDIGSVRRLDVGALRFKHILVAILVILISSIAYVISQQNM", "output": "Together with WIT2, required for the nuclear envelope docking of RANGAP proteins in root tips."}]}
+{"id": "function_test_688", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MATASARWNHVWVGTETGILKGVNLQRKHAANFTPSGQPRREEAVNALCWGTGGETQILVGCADRTVRYFNAEEGTFLSQRYCPGGEGTFRGLAQADGTLITCVDSGILRVWCENDKEASSDPLLELKVGPGVCRMRQDPTHTHVVATCGKENALKVWDLQGSEEPVFRAKNVRNDWLDLRVPIWDQDTQFLPGSQKLVTCTGYHQVRVYDPVSPQRRPVLEATYGEYPLTAMTLTPEGNSVIVGNTHGQLAEIDFRQGRLLGCLKGLAGSVRGLQCHPSKPLLASCGLDRVLRIHRIRNPRGLEHKVYLKSQLNCLLLSGRDNWEDEPQEPQEPNQVPSEDTETDELWASLEAAAKRKLPDLDQTQGALQRRKKKKRPGSTSP", "output": "Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit. Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL (By similarity). Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development ."}]}
+{"id": "function_test_689", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAGSGRDDPLVVGRIVGDVLDPFVRITNLSVSYGARIVSNGCELKPSMVTQQPRVVVGGNDMRTFYTLVMVDPDAPSPSNPNLREYLHWLVTDIPGTTGATFGQEVMCYESPRPTMGIHRLVFVLFQQLGRQTVYAPGWRQNFSTRNFAELYNLGSPVATVYFNCQREAGSGGRRVYP", "output": "Probable mobile flower-promoting signal (florigen) that moves from the leaf to the shoot apical meristem (SAM) and induces flowering. Promotes the transition from vegetative growth to flowering under long day (LD) conditions. Acts upstream of MADS14 and MADS15. May also participate in the promotion of flowering under short day (SD) conditions."}]}
+{"id": "function_test_690", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSSLLNISHCSYHGYSGLTSRGGINTVENHRWVWHNNGVRLSFPRAESSINITMGCTLQRGIAKSLSQENLVELSDENDDLCPVECVTEFKTDDELLSVLEKSKETNSLVVVDFYRTACGSCKYIEQGFSKLCKQSGDQEAPVIFLKHNVVDEYDEQSEVAERLRIKAVPLFHFYKNGVLLESFATRDKERIDAAILKYTSSES", "output": "Probable thiol-disulfide oxidoreductase that may participate in various redox reactions."}]}
+{"id": "function_test_691", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MASAVFRLLQQGPRRLLAPAVPTLAPPVRGVKKGFRAAFRFQKELERWRLLRCPPPPVRRSEKPNWDYHAEVQAFGSRLQETFSLDLLKTAFINSCYIKSEEAKRQSLGIEKEAALLNLKDNQELFEQGLSFSHRCLTQFLEDEFPDLPAEGTESLVSFLTGEAVVCHVARNLAVEQLTLSAEFPVPLPVLRQTFFAVIGALLQSSGPERAALFIRDFLITQMTGKELFEMWTVVNPMGLLVEELKKRNISAPESRLTRQSGSTTALPLYFVGLYCDRKLIAEGPGETVLVAEEEAARVALRKLYGFTENRRPWDYSKPKESPKRAEQTSVAS", "output": "Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome."}]}
+{"id": "function_test_692", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDDGDLGNNHHNFLGGAGNRLSAESLPLIDTRLLSQSELRALSQCSSLSPSSSASLAASAGGDDDLTPKIDRSVFNESAGSRKQTFLRLRLARHPQPPEEPPSPQRQRDDSSREEQTQVASLLRSLFNVDSNQSKEEEDEGEEELEDNEGQIHYNSYVYQRPNLDSIQNVLIQGTSGNKIKRKRGRPRKIRNPSEENEVLDLTGEASTYVFVDKTSSNLGMVSRVGSSGISLDSNSVKRKRGRPPKNKEEIMNLEKRDSAIVNISAFDKEELVVNLENREGTIVDLSALASVSEDPYEEELRRITVGLKTKEEILGFLEQLNGEWVNIGKKKKVVNACDYGGYLPRGWRLMLYIKRKGSNLLLACRRYISPDGQQFETCKEVSTYLRSLLESPSKNQHYYLQSDNKTLGQQPVIANESLLGNSDSMDSETMQYLESGRTSSEVFEEAKAVENGNEADRVKTSLMQKDDNADFLNGVEDNDDDMKKRDGNMENLATLSNSEMTKSLPTTTNELQQYFSSQINRVQ", "output": "Probable transcriptional regulator (By similarity). May regulates developmental traits such as flowering time."}]}
+{"id": "function_test_693", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLLHFSPAKPLISPPNLRRNSPTFLISPPRSLRIRAIDAAQIFDYETQLKSEYRKSSALKIAVLGFGNFGQFLSKTLIRHGHDLITHSRSDYSDAANSIGARFFDNPHDLCEQHPDVVLLCTSILSTESVLRSFPFQRLRRSTLFVDVLSVKEFPKALFIKYLPKEFDILCTHPMFGPESGKHSWSGLPFVYDKVRIGDAASRQERCEKFLRIFENEGCKMVEMSCEKHDYYAAGSQFVTHTMGRVLEKYGVESSPINTKGYETLLDLVENTSSDSFELFYGLFMYNPNALEQLERLDMAFESVKKELFGRLHQQYRKQMFGGEVQSPKKTEQKLLNDGGVVPMNDISSSSSSSSSSS", "output": "Involved in the biosynthesis of tyrosine. Has a weak prephenate dehydrogenase activity."}]}
+{"id": "function_test_694", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEDAGEHLRCNDNVNDEERLPLEFMIGNSTSTAELQPPPPFLVKTYKVVEDPTTDGVISWNEYGTGFVVWQPAEFARDLLPTLFKHCNFSSFVRQLNTYGFRKVTTIRWEFSNEMFRKGQRELMSNIRRRKSQHWSHNKSNHQVVPTTTMVNQEGHQRIGIDHHHEDQQSSATSSSFVYTALLDENKCLKNENELLSCELGKTKKKCKQLMELVERYRGEDEDATDESDDEEDEGLKLFGVKLE", "output": "Transcriptional regulator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE)."}]}
+{"id": "function_test_695", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSSTESPGRTSDKSPRQQVDRLLLGLRWQRLEEPLGFIKVLQWLFAIFAFGSCGSYSGETGALVLCNNEAKDVSSIIVLFGYPFRLYQVQYEMPLCDQDSTSKTMNLMGDFSAPAEFFVTLGIFSFFYTMAALVIYLRFHKLYTENKRFPLVDFCVTVSFTFFWLVAAAAWGKGLTDVKGATRPSSLTAAMSVCHGEEAVCSAGATPSMGLANLSVLFGFINFFLWAGNCWFVFKETPWHGQGQDQGQGPSQESAAEQGAVEKQ", "output": "Involved in communication between the T-tubular and junctional sarcoplasmic reticulum (SR) membranes."}]}
+{"id": "function_test_696", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKLYNLKDHNEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEIDEMLKLDFVTRSAKILSAFIGDEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGPTLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRGKISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLAQICYYFEAVAQLPQETRNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVNDTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDETTQQTMRELKELGYTSEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESVEAILGETLDLPKELAERADLPLLSHNLPADFAALRKLMMNHQ", "output": "Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. To a lesser extent, is able to slowly catalyze the deamination of L-threonine into alpha-ketobutyrate and that of L-serine and 3-chloroalanine into pyruvate. Is also able to rapidly convert vinylglycine to threonine, which proves that the pyridoxal p-quinonoid of vinylglycine is an intermediate in the TS reaction."}]}
+{"id": "function_test_697", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTYRCLLPMVLLLCFSTTALSRSYSLLRFQQRRSAEVCQKLLGQLHSTPQHCLEAKMDFQVPEEMNQAQQFRKEDAILVIYEMLQQIFNILTRDFSSTGWSETIIEDLLVELYGQMNRLQPIQKEIMQEQNFTMGDTTVLHLKKYYFNLVQYLESKEYNRCAWTVVRVQILTNFSFLMRLTASLRD", "output": "Has antiviral, antibacterial and anticancer activities."}]}
+{"id": "function_test_698", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPLVLFTGYPCSGKTTLAKHLVQLLQSKIDATPSLSKYSITYHSDESLGIKHSDYITSQDERKLRSEIISAVKRDLSKNKIVIVDSLNYIKGFRYQLHCEVKNLSTTFCVIQTLCPPETIFEWNKTSNPNPWEPELLNQLIQRYEEPNSSNRWDSPLFAILTPQDNITDYIDDICKVVFQTSKSAKNSGHNDPLSKGLQKPNSATVLKPASQSNFIQVLDIETSKIIKTIMNHIKSLTSIGGVSNGTRVIVSEGITDINDDGCFFVDLPIGNVVTLAQLQRLKRQFINFNKLRDIDQDRIGPLFADYLNKNLN", "output": "Elongator complex-associated factor that is not a structural subunit but rather transiently contacts the complex. Regulates elongator complex gamma-toxin target (TOT) activity, resulting in G1 block by Kluyveromyces lactis toxin zymocin (pGKL1 killer toxin), probably through regulation of the ELP1/IKI3 subunit phosphorylation state. Required for an early step in synthesis of 5-methoxycarbonylmethyl (mcm5) and 5-carbamoylmethyl (ncm5) groups present on uridines at the wobble position in tRNA."}]}
+{"id": "function_test_699", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEKENITIDPRSSFTPSSSADIPVPPDGLVQRSTRIKRIQTTAMLLLFFAAVINYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAYGIAQLPCGPLLDRKGPRLMLGLGMFFWSLFQAMSGMVHNFTQFVLVRIGMGIGEAPMNPCGVKVINDWFNIKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYRNREHVELTAVEQAYLNAGSVNARRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWLVKGGMAPIKSRKICIIAGMFCSAAFTLIVPQATTSMTAVLLIGMALFCIHFAGTSCWGLIHVAVASRMTASVGSIQNFASFICASFAPIITGFIVDTTHSFRLALIICGCVTAAGALAYIFLVRQPINDPRKD", "output": "Probably responsible for the transport of L-galactonate from the periplasm across the inner membrane. Is essential for growth on L-galactonate as the sole carbon source."}]}
+{"id": "function_test_700", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MMSDYNWFEGIPFPAISYQREILEDIRNKFVVKEEDLLILTYPKSGTNWLNEIVCLIQTKGDPKWIQTVPIWDRSPWIETEIGYSAIINKEGPRLITSHLPIHLFSKSFFSSKAKAIYLMRNPRDILVSGYFFWGNTNLVKNPGSLGTYFEWFLQGNVLFGSWFEHVRGWLSMREWDNFLVLYYEDMKKDTKGTIKKICDFLGKNLGPDELDLVLKYSSFQAMKENNMSNYSLIKEDRVTNGLKLMRKGTTGDWKNHFTVAQAEAFDKVFQEKMAGFPPGMFPWE", "output": "Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze sulfonation of hydroxysteroids and xenobiotics."}]}
+{"id": "function_test_701", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDLSLLKALSEADAIASSEQEVRQILLEEADRLQKEVRFDGLGSVLIRLNESTGPKVMICAHMDEVGFMVRSISREGAIDVLPVGNVRMAARQLQPVRITTREECKIPGLLDGDRQGNDVSAMRVDIGARSYDEVMQAGIRPGDRVTFDTTFQVLPHQRVMGKAFDDRLGCYLLVTLLRELHDAELPAEVWLVASSSEEVGLRGGQTATRAVSPDVAIVLDTACWAKNFDYGAANHRQIGNGPMLVLSDKSLIAPPKLTAWVETVAAEIGVPLQADMFSNGGTDGGAVHLTGTGVPTVVMGPATRHGHCAASIADCRDILQMQQLLSALIQRLTRETVVQLTDFR", "output": "Has a broad aminopeptidase activity on non-blocked peptides by progressively cleaving amino acids off the peptide substrate. Aminopeptidase activity stops at the residue before the first proline in the peptide. Cannot cleave when proline is the first N-terminal residue."}]}
+{"id": "function_test_702", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPMFVVNTNVPRASVPDGLLSELTQQLAQATGKPAQYIAVHVVPDQLMTFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLTERLRISPDRIYINFCDMNAANVGWNGSTFA", "output": "Pro-inflammatory cytokine involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity."}]}
+{"id": "function_test_703", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MELDDASRHGFGRMGFGCKHYRRRCRIRAPCCNDVFHCRHCHNESTKDGHELDRHAVESVICLVCDTEQPVAQVCYNCGVCMGEYFCSACKFFDDDVDREHFHCQDCGICRVGGKDNFFHCEKCGSCYSVSLRDKHCCIENSMKNNCPICYEYLFDSLRETSVLRCGHTMHLQCFHEMLKHDKFSCPICSMPIFDMDKFLRALDAEIEANMLHIDYMGKGWIVCNDCRDTTQVYARVAGHKCCHCQSHNTCRVAAPVLPA", "output": "Possesses E3 ubiquitin-protein ligase activity in vitro. Possesses transactivation activity in yeast cells. May modulate abiotic stress responses by negatively regulating antioxidant enzymes-mediated reactive oxygen species (ROS) removal."}]}
+{"id": "function_test_704", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAYSKITLLAALAAIAYAQTQAQINELNVVLDDVKTNIADYITLSYTPNSGFSLDQMPAGIMDIAAQLVANPSDDSYTTLYSEVDFSAVEHMLTMVPWYSSRLLPELEAMDASLTTSSSAATSSSEVASSSIASSTSSSVAPSSSEVVSSSVAPSSSEVVSSSVAPSSSEVVSSSVASSSSEVASSSVAPSSSEVVSSSVASSSSEVASSSVAPSSSEVVSSSVAPSSSEVVSSSVASSSSEVASSSVAPSSSEVVSSSVASSTSEATSSSAVTSSSAVSSSTESVSSSSVSSSSAVSSSEAVSSSPVSSVVSSSAGPASSSVAPYNSTIASSSSTAQTSISTIAPYNSTTTTTPASSASSVIISTRNGTTVTETDNTLVTKETTVCDYSSTSAVPASTTGYNNSTKVSTATICSTCKEGTSTATDFSTLKTTVTVCDSACQAKKSATVVSVQSKTTGIVEQTENGAAKAVIGMGAGALAAVAAMLL", "output": "Component of the cell wall. Required for anaerobic growth."}]}
+{"id": "function_test_705", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRPAVRALLACAVLGLCLADPERTVRWCTISTHEANKCASFRENVLRILESGPFVSCVKKTSHMDCIKAISNNEADAVTLDGGLVYEAGLKPNNLKPVVAEFHGTKDNPQTHYYAVAVVKKDTDFKLNELRGKKSCHTGLGRSAGWNIPMAKLYKELPDPQESIQRAAANFFSASCVPCADQSSFPKLCQLCAGKGTDKCACSNHEPYFGYSGAFKCLMEGAGDVAFVKHSTVFDNLPNPEDRKNYELLCGDNTRKSVDDYQECYLAMVPSHAVVARTVGGKEDVIWELLNHAQEHFGKDKPDNFQLFQSPHGKDLLFKDSADGFLKIPSKMDFELYLGYEYVTALQNLRESKPPDSSKDECMVKWCAIGHQERTKCDRWSGFSGGAIECETAENTEECIAKIMKGEADAMSLDGGYLYIAGKCGLVPVLAENYKTEGESCKNTPEKGYLAVAVVKTSDANINWNNLKDKKSCHTAVDRTAGWNIPMGLLYSKINNCKFDEFFSAGCAPGSPRNSSLCALCIGSEKGTGKECVPNSNERYYGYTGAFRCLVEKGDVAFVKDQTVIQNTDGNNNEAWAKNLKKENFEVLCKDGTRKPVTDAENCHLARGPNHAVVSRKDKATCVEKILNKQQDDFGKSVTDCTSNFCLFQSNSKDLLFRDDTKCLASIAKKTYDSYLGDDYVRAMTNLRQCSTSKLLEACTFHKP", "output": "Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation."}]}
+{"id": "function_test_706", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAAAALLLLAAAAAIVVVAMVLRWLLLLGGPAAGRLGKRALMPPGSTGLPLIGETLRLISAYKTPNPEPFIDERVARHGGVFTTHVFGERTVFSADPAFNRLLLAAEGRAVHSSYPSSIATLLGARSLLLTRGAAHKRLHSLTLTRLGRPASPPLLAHIDRLVLATMRQWEPAATVRLMDEAKKITFNLTVKQLVSIEPGPWTESLRREYVKLIDGFFSIPFPLANLLPFTTYGQALKARKKVAGALREVIKKRMEEKAENGGSIGDDEGKKEKKDMVEELLEAEGGSFSEEEMVDFCLSLLVAGYETTSMLMTLAVKFLTETPAALAELKEEHANIRDMKGKKQPLEWSDYKSMPFTQCVINETLRVGNIISGVFRRANTDIHYKDYTIPKGCKIFASFRAVHLNNEHYENARTFNPWRWQINNKLQNAVGANIFTPFGGGPRLCPGYELARVVVSIFLHHLVTRFSWEETEEDRLVFFPTTRTLKGYPINLRLLSESIC", "output": "Catalyzes the C23-alpha-hydroxylation step in brassinosteroid biosynthesis (Probable). Converts 6-deoxocathasterone (6-deoxoCT) to 6-deoxoteasterone (6-deoxoTE) in the late C6-oxidation pathway and cathasterone (CT) to teasterone (TE) in the early C6-oxidation pathway of brassinolide (BL) biosynthesis (Probable)."}]}
+{"id": "function_test_707", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSFTRKKGFYKQDVNKTAWELPKTYVSLTHIGSGAYGSVCSAIDKRSGEKVAIKKLSRPFQSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFHDFYLVMPFMQTDLQKIMGMEFSEDKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHTDVEMTGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTGVPGAEFVQKLNDKAAKSYIQSLPQSPKKDFSQLFPRASPQATDLLEKMLELDVDKRLTASQALAHPFFEPFRDPEEETEAQQPLEDSLEREKLIVDEWKQHIYKEIVNFSPIARKDSRRRSGMKLQ", "output": "Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK13 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as pro-inflammatory cytokines or physical stress leading to direct activation of transcription factors such as ELK1 and ATF2. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. MAPK13 is one of the less studied p38 MAPK isoforms. Some of the targets are downstream kinases such as MAPKAPK2, which are activated through phosphorylation and further phosphorylate additional targets. Plays a role in the regulation of protein translation by phosphorylating and inactivating EEF2K. Involved in cytoskeletal remodeling through phosphorylation of MAPT and STMN1. Mediates UV irradiation induced up-regulation of the gene expression of CXCL14. Plays an important role in the regulation of epidermal keratinocyte differentiation, apoptosis and skin tumor development. Phosphorylates the transcriptional activator MYB in response to stress which leads to rapid MYB degradation via a proteasome-dependent pathway. MAPK13 also phosphorylates and down-regulates PRKD1 during regulation of insulin secretion in pancreatic beta cells (By similarity)."}]}
+{"id": "function_test_708", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAAAARARVTHLLRHLQSTACQCPTHSHTYSQVPGLSPSGKTTDYAFEMAVSNIRYGAGVTKEVGMDLQNMGAKNVCLMTDKNLSQLPPVQIVMDSLSKNGISFQVYDNVRVEPTDGSFMDAIEFAKKGAFDAYVAVGGGSTMDTCKAANLYACSPHSEFLDYVNAPIGKGKPVTVPLKPLIAVPTTSGTGSETTGVAIFDYEHLKVKTGIASRAIKPTLGLVDPLHTLHMPCQVVANSGFDVLCHALESYTAIPYSMRSPCPSNPIQRPAYQGSNPISDIWAVHALRIVAKYLKRAVRNPDDLEARSSMHLASAFAGIGFGNAGVHLCHGMSYPISGLVKTYKAKEYNVDHPLVPHGLSVVLTSPAVFTFTAQMFPERHLETAEILGANIRTAKIQDAGPVLADALRKFLFDLNVDDGLAALGYSKDDIPSLVKGTLPQERVTKLAPRAQSEEDLSALFEASMKLY", "output": "Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2-KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity)."}]}
+{"id": "function_test_709", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGDVNFLQKAIQIVQQATEQDNAKNYAEAHRLYIQSLEWFTTALKYEKSERSKATIKAKTLEYLQRAEQLKEYLDKSKNKKPVAVGGNKSNSAGSANGAGKSAKEDDEDMDPEDKKRNDSLSSSIVTTKPNVKWDDVAGLYQAKEYLKEAVIFPIKFPQMFTGNRKPWKGILLYGPPGTGKSYLAKAVATEISSTFFSISPSDIVTKWLGDSEKLVKQLFEMAREKNNSVIFIDEVDSLCSSRNDQESESARRIKTEFLIQMNGVGNDSDGILVLAATNIPWGLDLAIRRRFEKRIYIGLPEPQARAKMFQIHIGSTPNTLVQADYKKLADLTEGYSGSDIGSLVKDAIMQPVRAVQCATHFKQIRAPSREDPSVMTDYVTPCSPGDPLAQEMTWMDIDPTKLKEPEITIADCLKSLRVIKPSVNKADLDRYVEFTNDFGQDGV", "output": "Involved in intracellular protein transport probably out of a prevacuolar endosomal compartment. May be involved in the release of components of the bilayered coat from the endosomal membrane. The association with ESCRT-III complex mediates the ATP-dependent disassembly of the ESCRT-III complex (By similarity)."}]}
+{"id": "function_test_710", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MQLKDGGTGMSRRRKHADSPARRSTPHRAAAKNCRPAAEPWLRESRAACSSQLRRAGTRSARRAQRQAAADGGRSPRGKETPVQIVKMDLLSCTFSSPNDPDGQTDIFWDQNSPMTKQLGKGRKKQISSAYSDEISHIVNRIAPQDEKPVTNSMLGVWIGETAIPCTPGVAKEKSRVKASCTKLKTKNREKELMKLAQQFDKNMEELDVIQEQDGKNHDFIQMTSKMGHLDNHKDSVQKPSGDVVPEITCTPVKKQMKGDSRISLAKAQDSSQKPFDQNVEAAFNAIFDGSTQMCSGQLSQDLLDAFLNNSKTSLRKKNALLQEEIITTETLLTENLLNKTPISLSPQIDTTVILNSCVTPCPKTPAAPDTQLDELTANDFEDDWESLLGSEPFLMENAEMLEFVPSTTAQDTCQKAICTSVGENDTITSRTNMNLGGRLRDSKVTLDLPSKTRNGELRNAGEHRFSSHPGDESRKVPFTGNKVSFEKSVTSIVSKDEDYVAVSNLEKVKEDSRNKCILNKHSSNKSSSYTRYPSKQSSELGVNLPLQVPTTDPFDSVFLGKENIVCSTNQSHGSKLNSSFDDWNDPLLASEMVEACHRLEATWDAGEVDDDLFCQACDDIERLTQQENKGSEESESVSYTSTRGSRSSSTASKQASQSAPSKHWNVVSSAVPLSLANKSQMSKPVTVQKRGRCGDGPNILDATNLSVCSKNSSDNKRGPVQVNSSKFVLGGSSNLNVNLGLMSTKIATNMKLSTQQLSHNSLADTAQNDNKILKLPKFTFKKKNPQLNQNHLVGSVPVGKISEDLGKRETVNSLLEANQQQSSINYSESLKPSSPDEEERNRKYSPEEIQRKRQEALVRRKAKALHTVQSAPISLP", "output": "Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity. Recruited to stalled replication forks via interaction with the RPA complex and directly stimulates ATR kinase activity independently of TOPBP1. Probably only regulates a subset of ATR targets."}]}
+{"id": "function_test_711", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSRGYPENNNFLNNNNQMVLDMILYPLIGIPQTINWETVARLVPGLTPKECVKRFDELKSCGSSPVDNQYNPLMATGEGPVETLATYIKSSLLDTQGDFQETPVDQDTVSKAGRHSIATTRNCSSESENCTARNAGEETGESEGPNMVIHVCDEAKSLKEDFICPRDLLISEMKYFAEYLSMDAQRWEEVDISVHCDVHIFNWLIKYVKRNTKESKDCEIPALEPGNVISILISSEFLKMDSLVEQCIQYCHKNMNAIVAAPCNMNCINANLLTRIADLFTHNEIDDLKDKKDKFRSKLFCKKIERLFDPEYSNPDSRNNAATLYRCCLCKKLLTRETERRIPCIPGKINVDRHGNIIYIHIRDKTWDVHEYLNSLFEELKSWRDVYWRLWGTVNWLTCSRCYQAFLCIEFSHCQYHSEVVVYSSTVNSLNTVGTGIYPCCNQKVLRFDPTQLTKGCKVRDHMVVLHDQGENDDSPSCPPAKILDDLHKHKDVIAVPFLKDAVSDPGVGSCDEKGLEYEILLEPNTPWGSKTGELNAFLSLKNWTLQLKQQSLFSEEEEYTTGSEVTEDEVGDEEEIAKKQRKKEKPKKFTKPPKKQLSSPCSQKKEKTLEKSTSRDVSPFVVSMQKNKWDASRSLRFNQDAQREDDQRRMSEITGHLIKMRLGDLDRVKAKESKEFAGGIYSRLEAQVRASVPVTARQNSSDKNQRSKSRFGQGRPA", "output": "Negatively regulates class switch recombination or isotype switching in splenic B-cells."}]}
+{"id": "function_test_712", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAAAAEDVEFVDYDRDEEEEEDAMDEDDRGGGRGGRALPVPHIVSQGVMRSRGRLLGRSTSVLASNRDRFDSLADAGNPGHGPQRSIEGWILLVSGVKEDAEEDDLYNTFSDFGHVKDLHLNLERRTGYAKGYALVEYESFEEAQTAIKAMNGTQLLTRTVYVDWAFSRGPIQKLTSTRPLHRRSRTPPRRLAALTC", "output": "Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all stages of mRNA metabolism thereby influencing downstream processes including nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD). The MAGO-Y14 heterodimer inhibits the ATPase activity of EIF4A3, thereby trapping the ATP-bound EJC core onto spliced mRNA in a stable conformation. The MAGO-Y14 heterodimer interacts with the EJC key regulator PYM leading to EJC disassembly in the cytoplasm (By similarity). EJC core heterodimers play essential roles in plant growth and development, and pollen and seed development . The MAGO-Y14 heterodimer selectively binds to the UDT1 (UNDEVELOPED TAPETUM 1) pre-mRNA transcript and regulates the splicing of UDT1, a key regulator in stamen development ."}]}
+{"id": "function_test_713", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MHLGLLALALVFFSSMGHADNLKASKARRQRRISTEVPPSCSNGCEHCSEYNGCLKCRPRLFILLERNDIRQIGICLAACPVGYYGIRNRDMNKCTQCKIENCEACFSRNFCTKCKEGLYSHRGRCFSSCPEGFTVNGTMECVVQCDLSEWSPWGPCMKKNKTCGFKKGNQTRTREPLQVPSPATSTGAAPASGCVPEIQTQRCTVQKKIPCKGENKKNQQNRGENSKNRGRDSKERGGNKKRKNTNRSTTVPTITTSMVT", "output": "Activator of the canonical Wnt signaling pathway by acting as a ligand for lgr4-6 receptors. Upon binding to lgr4-6 (lgr4, lgr5 or lgr6), lgr4-6 associate with phosphorylated lrp6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Acts both in the canonical Wnt/beta-catenin-dependent pathway and in non-canonical Wnt signaling pathway (By similarity)."}]}
+{"id": "function_test_714", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNMARNVTDLLALSQQEELVDLPENYPLSTSEDEGDSDGEGKRQKLLEAVSSLGRKNKWKLAERSEASRMVSEFNVTSEGSGEKLVLSDLLGSATALSSVAAVKKQLHRVKSKTLTPPLNKEEADRALREAAFSKTSQMLSRWDPVVLKNRQAEQLIFPMEKEPPAVAPIEHVFTDWKVRTPLEQEVFNLLHKNKQPVTDPLLTPVETASIRAMSLEEAKIRRAELQRMRALQSYYEARARREKRIKSKKYHRALKKGKAKKALKEFEELWKDCPNAALQELEKMEKARMTERMSLKHQGSGKWAKSKAIMAKYDPEARKAMQEQLAKNRELTQKLQVVSESEEEDGCTEEGIVSVSHGMDDLQMNADGVNPWMLSSCNSNAKRGEIKTDPEQMPEFVAHVSSESEGDERPVAEELVLKERSFQERVDPNNAKLMDGQETEDSDSQEVLQKLNKESHQSDNQKVSSEENVLHIQREDLASEKLLVLQRLERAHVLEQQGELSKEEHYPKKGLSRPLLKGDWKEMKPLTNPDASGGKKKKEQMIDLRNLLTANSSPVRSLAVPTIQQLEDEVETDHKQLIREAFAGDDVIREFLKEKREAIETNKPKDLDLSLPGWGEWVGMGLKPSAKKRRRFLIKAPESSPRKDKNLPNVIISEKRNIHAAAHQVRALPHPFTHQQQFERTIQNPIGYMWNTQRTFQKLTVPKVGTKLGHIIKPIKAENVGYCSSTRSDLSILQSSQKCLSRKQQKQLKKLSSAD", "output": "Essential for spermatogenesis. May be required specifically for ribosome biogenesis and hence protein synthesis during male meiosis."}]}
+{"id": "function_test_715", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSVVMLVFRVLLLIALVGNSAIGLSLMPFIAPPDPDWTPDDYYYSYEQSSPDKDASVTQTSPENPDWYYEDDDPCQSNPCEHGGDCIIRGNTFSCSCPAPFSGSRCQTVQNKCKDNPCVQGDCLITQTPPYYRCACKYPYTGPDCSKVLPVCRPNPCQNGGVCSRHRRRSRFSCACPDQYKGRFCEIGPDDCYVGDGYSYRGKVSRTVNQNPCLYWNSHLLLQENYNMFMEDAETHGIADHNFCRNPDGDHKPWCFVKVNSEKVKWEYCNVEVCPESDAANPVGSLQEPVMELPGFDSCGKTEMTEHAVKRIYGGFKSTAGKHPWQVSLQTSLPLTTSMPQGHFCGGSLIHPCWVLTAAHCTDMSTKHLKVVLGDQDLKKTESHEQTFRVEKILKYSQYNERDEIPHNDIALLKLKPVGGHCALESKYVKTVCLPSDPFPSGTECHISGWGVTETGEGSRQLLDAKVKLIANALCNSRQLYDHTIDDSMICAGNLQKPGSDTCQGDSGGPLTCEKDGTYYVYGIVSWGQECGKKPGVYTQVTKFLNWIKTTMHKEAGL", "output": "Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro-urokinase) to the active two chain form. Activates coagulation factor VII (By similarity)."}]}
+{"id": "function_test_716", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MESVLSKYENQITIFADYLEEFPDTDELVWILGKQHLLKTEKSKLLSDISARLWFTYRRKFSPIGGTGPSSDAGWGCMLRCGQMMLAQALICRHLGRDWNWEKQKEQPKEYQRILQCFLDRKDCCYSIHQMAQMGVGEGKSIGEWFGPNTVAQVLKKLALFDEWNSLAVYVSMDNTVVIEDIKKMCRTLSLSADTPAERPLESLTASNQSKGPSACCTAWKPLLLIVPLRLGINQINPVYVDAFKECFKMPQSLGALGGKPNNAYYFIGFLGDELIFLDPHTTQTFVDTEENGTADDQTFHCLQPPQRMNILNLDPSVALGFFCKEEKDFDSWCSLVQKEILKENLRMFELVQKHPSHWPPFVPPAKPEVTTTGAEFIDSTEQLEEFDLEEDFEILSI", "output": "Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins. The protease activity is required for proteolytic activation of ATG8 family proteins: cleaves the C-terminal amino acid of ATG8 proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Protease activity is also required to counteract formation of high-molecular weight conjugates of ATG8 proteins (ATG8ylation): acts as a deubiquitinating-like enzyme that removes ATG8 conjugated to other proteins, such as ATG3. In addition to the protease activity, also mediates delipidation of ATG8 family proteins. Catalyzes delipidation of PE-conjugated forms of ATG8 proteins during macroautophagy. Compared to ATG4B, the major protein for proteolytic activation of ATG8 proteins, shows weaker ability to cleave the C-terminal amino acid of ATG8 proteins, while it displays stronger delipidation activity. Involved in phagophore growth during mitophagy independently of its protease activity and of ATG8 proteins: acts by regulating ATG9A trafficking to mitochondria and promoting phagophore-endoplasmic reticulum contacts during the lipid transfer phase of mitophagy.; "}]}
+{"id": "function_test_717", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNLKVLLLLLGLSFLTVFALVYVLLTRQGSFSQSPRCPSIPPRIHPWTHPSQSQLFADLTPEELTAVMSFLTKHLGPGLVDAAQARPSDNCVFSVELQLPAKAAALAHLDRGGPPPVREALAIIFFGGQPKPNVSELVVGPLPHPSYMRDVTVERHGGPLPYYRRPMQKTEFVQIWRHLKEVELPKAPTFLASVLNYNGSTLAPLHSTASGFHAGDRATWIALYHNISGLGVFLHPVGLELLLDHGALDPADWVVQQVFYLGHYYADLAQLEWEFKVGRLEVIRVPLPTPGGASSLRPRVTPDPPLPPLQFSLQGPQYNIQGNSVTSPLWTFTFGHGVFSGLRIFDIRFKGERVAYEVSVQECLTVYGADSPKTMTIRYLDSSYGLGLNSRALVRGVDCPYQATMVDIHVLVGTGSVQLLPGAVCVFEEAQGLPLRRHHNGIGGHFYGGLASSSLVVRSVSSVGNYDYIWDFMLHPTGALEARVHATGYINTAFMSGGAESLLFGNRVGERVLGAVHTHAFHFKLDLDVAGLKNWVIAEDAVFKPVAAPWNPELQLQRPQLTRQVLSREDLAAFPWGSPLPRYLYLATNQTNAWGHQRGYRIQIHSPPGVHVPLESSEERALSWGRYQLVVTQRKEAEPHSSSIYYQNDMRSPATVFADFINNETLLGEDLVAWVTASFLHIPHAEDIPNTVTVGNRVGFLLRPYNFFNEDPSIFSPGSVYFERDQDAGLCSINPVACTQQLADCVPNLPSFSYEGL", "output": "Has a monoamine oxidase activity with substrate specificity for 2-phenylethylamine and tryptamine. May play a role in adipogenesis. May be a critical modulator of signal transmission in retina (By similarity)."}]}
+{"id": "function_test_718", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MANPWWTNQSGLAGMVDHSVSSGHHQNHHHQSLLTKGDLGIAMNQSQDNDQDEEDDPREGAVEVVNRRPRGRPPGSKNKPKAPIFVTRDSPNALRSHVLEISDGSDVADTIAHFSRRRQRGVCVLSGTGSVANVTLRQAAAPGGVVSLQGRFEILSLTGAFLPGPSPPGSTGLTVYLAGVQGQVVGGSVVGPLLAIGSVMVIAATFSNATYERLPMEEEEDGGGSRQIHGGGDSPPRIGSNLPDLSGMAGPGYNMPPHLIPNGAGQLGHEPYTWVHARPPY", "output": "Transcription factor that specifically binds AT-rich DNA sequences related to the nuclear matrix attachment regions (MARs) (By similarity). Negatively regulates plant innate immunity (PTI) to pathogens through the down-regulation of the PAMP-triggered NHO1 and FRK1 expression ."}]}
+{"id": "function_test_719", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSRQVTRLLGSLRHSGGGCSGSSKVCSLTSLVQSRSFGTTPPPPAAVFVDKNTRVICQGITGKNGTFHTEQAIEYGTKMVAGVTPKKGGTEHLGLPVFNTVAEAKAETKANASVIYVPAPFAAAAIMEGLAAELDLIVCITEGIPQHDMVRVKAALNSQSKTRLIGPNCPGIIKPGECKIGIMPGYIHKPGKIGIVSRSGTLTYEAVFQTTAVGLGQSTCVGIGGDPFNGTNFVDCLEKFFVDPQTEGIVLIGEIGGTAEEDAAALIKENGTDKPVVAFIAGLTAPPGRRMGHAGAIVSGGKGTAQDKIKSLRDAGVKVVESPAKIGAAMFELFQERGLLK", "output": "Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit."}]}
+{"id": "function_test_720", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEKLRKVVNEIAYTRVHTNSPALHRSLVPFLTIASSLYGVALQIRRSLYRYSLLQKHRLPVPVISVGNLSWGGNGKTPMVEYISQFLVDSGLTPLILTRGYAGGDEVKMLERHLRGGPVKIGVGANRAATAALFLDKYGCVDSSSLRSFFDLHERAQVWTISEKIGCIILDDGMQHWSLSRDLEIVMLNGLNPWGNGHLMPHGPLREPLLALERADVAVVHHVDLITKQSLRDIENMIQGFKKSIPIFYSKMVPKYLFDVKNARSHVALEALRCASVLCVSAIGSADAFVKSIEMTGAHYVDRLDFSDHHLFEAEDVETMSRRAKGLEHKSNCKPIIVVTEKDYDRDPEILKCLDSYTVLVLCSELQITPILETDVDSFNYTLMKALAAKFYVSS", "output": "Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that in bacteria anchors the lipopolysaccharide to the outer membrane of the cell. Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). Lipid A-like molecules in plants may serve as structural components of the outer membranes of mitochondria and/or chloroplasts, or may be involved in signal transduction or plant defense responses (Potential)."}]}
+{"id": "function_test_721", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MELCVISTTTTVKAINPFLPSITRRVSSRLFQSDSVLQFGGRLKKPISRPLDMSCVSRKIGFFGDFMSHGGNFRLFAAASPAVETSVKEDKLPADLKVTETVQANSSVKLSVEVPEIVCEDCYQRVLTEFMKLSKVPGFRPKTRVPENIIVGFVGRQYVLRATVESILKRTLPHAMESVTGRALKDSIQIVSSFPDMEKAYSKLKTLSYEVVVDVVPELKWNPEDGYKNMKVVVELGDEIDAKKACERQLRQKYKSLGALKIVTERGLQVGDLAVVDISATTIDEDGSTGQAIPDAESKGFHFDTEEGNRLLPGFLDAIIGIRAGESKSFTLVFPESWKQESLRGQRAQFTVDCKELFYRDLPTLDDSLADKLLPGCTTLKEVEETLAKRCQEMEQEAKEQATDNAILEQIRKMVEVEIPQSLFEEQGRQFYGARLLEIQGNMKLNEDQLASLSSQKAVNEFLETQRESITNIIKQNIAVGDIFKRENLEFSTDELVKEVENSISEFKKHKQEFDEERVKDQVQEILEGAKVLEWLKDRAEIQYITR", "output": "Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity)."}]}
+{"id": "function_test_722", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEPDLNEEESERIRTSRNRRSLEHRRNSLLPFQWKATNNSRWMAQVVASEFSLVAFLLLLVMVFSKKWLYPSKSRFHQRYPQNVTKRVYTSIHSMSTGLLYICVSKSCPSSDNGEDNFKMWTIHPVFGVAKISFTLAIGLGFVLTTWLHLPYLPCLQRMPFFGLIGIILSFCEVTLIFLTLLLFPVNLWIYELRKNISVPIGWSYFIGWLVLILYFTCGILCYLNHKNYWSLIMSSTTINTACSSLGPESLVSPSQTPSSQENSQESPKDDQKPSSPDKVVSPPQPDTTG", "output": "Component of the outer dense fibers (ODF) of spermatozoa which could be involved in sperm tail structure, sperm movement and general organization of cellular cytoskeleton."}]}
+{"id": "function_test_723", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGWRQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEACSLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQGCREPPQREIEPPLFLFLSIAAFALFSLFTR", "output": "Probable chaperone protein which facilitates trafficking and functional cell surface expression of some G-protein coupled receptors (GPCRs). Promotes functional expression of the bitter taste receptor TAS2R16 (By similarity). Also promotes functional expression of the opioid receptor heterodimer OPRD1-OPRM1 ."}]}
+{"id": "function_test_724", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MMRSVDVYVKTLGPPVRSILYSIFTSQQKPSSLPSLPFHFSLRSSSNIPTRCFSNVVAKSNSPIYDFQGFRNLFTERAISSSTTTPVASAQPQQLQNQNQHPAEVDEEISMGLEDEAKLSIPVRAYFFSTSVDLRSLIEQNKQNFIPPTSRMTNYVVLKFGNHSDPTDTTRGRISGSESIYMVVFHYGSIVLFNVREHEVDEYLKVVERHASGLLPEMRKDEYEVRENPNLDTWMEVGRDFIRLQFLNTDGIRTIGCVLGQSIALDYYGRQVDGMVAEFTEINRQLEITGTFTMKRKKLFQLVGKANVILADVILKLGLFERSDIAWKDAKYGQIWEFLRDEFELTQSFANLDYKLKFVEHNVRFLQEILQNRKSATLEWLIIILISMEIAISFYNMSRASL", "output": "Mediates abscisic acid (ABA) signal transduction through mitochondrial retrograde regulation involving ABI4 during seed germination and seedling growth, and leading to the production of reactive oxygen species (ROS) by the alternative respiratory pathway . Required for the maintenance of mitochondrial structure ."}]}
+{"id": "function_test_725", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAQNDTVKLIGCSDDPFSIRPRVALHLKSIKYEYLEEPDDDLGEKSQLLLKSNPIHKKTPVLIHGDLAICESLNIVQYLDEAWPSDPSILPSNAYDRASARFWAQYIDDKCFEAANALTGANNDEERIAATGKLTECLAILEETFQKSSKGLGFFGGETIGYLDIACAALLGPISVIEMFSADKFVREETTPGLIQWAVRFRAHEAVRPYMPTVEEVTELVKQRIEEGFKRNFKSNVSTSEYE", "output": "May be involved in the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles and have a detoxification role against certain herbicides."}]}
+{"id": "function_test_726", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MADTTPNGPQGAGAVQFMMTNKLDTAMWLSRLFTVYCSALFVLPLLGLHEAASFYQRALLANALTSALRLHQRLPHFQLSRAFLAQALLEDSCHYLLYSLIFVNSYPVTMSIFPVLLFSLLHAATYTKKVLDAKGSNSLPLLRSVLDKLSTNQQNILKFIACNEIFLMPATVFMLFSGQGSLLQPFIYYRFLTLRYSSRRNPYCRNLFNELRIVVEHIIMKPSCPLFVRRLCLQSIAFISRLAPTVA", "output": "Acts as a regulator of the tubular endoplasmic reticulum (ER) network by modulating intracellular calcium homeostasis. Mechanistically, stimulates PKD2 calcium-dependent activity (By similarity). Suppresses the RTN3/4-induced formation of the ER tubules. Positively regulates PERK-mediated and IRE1-mediated unfolded protein response signaling. Plays an essential role in VEGF-mediated release of Ca(2+) from ER stores during angiogenesis. Also plays a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26. Participates in lipid metabolism by acting as a downstream effector of the pyruvate kinase/PKM. Forms a complex with RNF5 to facilitate polyubiquitination and subsequent degradation of SCAP on the ER membrane (By similarity)."}]}
+{"id": "function_test_727", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MYRKLAVISAFLATARAQSACTLQSETHPPLTWQKCSSGGTCTQQTGSVVIDANWRWTHATNSSTNCYDGNTWSSTLCPDNETCAKNCCLDGAAYASTYGVTTSGNSLSIGFVTQSAQKNVGARLYLMASDTTYQEFTLLGNEFSFDVDVSQLPCGLNGALYFVSMDADGGVSKYPTNTAGAKYGTGYCDSQCPRDLKFINGQANVEGWEPSSNNANTGIGGHGSCCSEMDIWEANSISEALTPHPCTTVGQEICEGDGCGGTYSDNRYGGTCDPDGCDWNPYRLGNTSFYGPGSSFTLDTTKKLTVVTQFETSGAINRYYVQNGVTFQQPNAELGSYSGNELNDDYCTAEEAEFGGSSFSDKGGLTQFKKATSGGMVLVMSLWDDYYANMLWLDSTYPTNETSSTPGAVRGSCSTSSGVPAQVESQSPNAKVTFSNIKFGPIGSTGNPSGGNPPGGNPPGTTTTRRPATTTGSSPGPTQSHYGQCGGIGYSGPTVCASGTTCQVLNPYYSQCL", "output": "Exocellobiohydrolases (CBH) that catalyzes the hydrolysis of 1,4-beta-D-glucosidic bonds in cellulose to release the disaccharide cellobiose. The degradation of cellulose involves an interplay between different cellulolytic enzymes. Hydrolysis starts with endoglucanases (EGs), which cut internal beta-1,4-glucosidic bonds in cellulose to reduce the polymerization degree of the substrate and create new chain ends for exocellobiohydrolases (CBHs). The CBHs release the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain. Finally, beta-1,4-glucosidases hydrolyze the cellobiose and other short cello-oligosaccharides into glucose units."}]}
+{"id": "function_test_728", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSLLLSNSALVGPKFRSSRISHASASLDIGLQRATSPQNASVATCFEETKGRIAKLFHKNELSVSTYDTAWVAMVPSPTSSEEPCFPACLNWLLENQCHDGSWARPHHHHMLKKDVLSSTLACILALKKWGVGEEQISRGLHFVELNFASATEKGQITPMGFDIIFPAMLDNARGLSLNLQLEPTTLNDLIYKRDLELKRCNQSNSAEKEVYWAHIAEGMGKLQDWESVMKYQRKNGSLFNSPSTTAAAFIALRNSDCLNYLYSAMNKFGSAVPAVYPLDIYSQLCLVDNLERLGISRFFSTEIQSVLDDTYRCWLDGDEEIFMDASTCALAFRTLRMNGYSVTSDSFTKAVQDCFSSSIPSHMRDVNTTLELYRASEIMLYPDEIELEKQHSRLRSLLEHELSSGSIQSSQLNAVVKHALDYPFYAILDRMAKKKTIEHYEFDDTRILKTSFCSPTFGNKDFLSLSVEDYNRCQAIHRKEFRELDRWFKETKLDELKFARQKYTYSYCTAAASFASPELSDARMSWAKNSVLIGIVDDLFDVKGSVEEKQNLIKLVELWDVDVSTQCCSQSVQIIFSALRSTICEIGDKGFKIQGRSITDHIIAIWLDVLYNMMKESEWAENKSVPTIDEYMKISHVSSGLGPVVLPSLYLVGPKLSQEMVNHSEYHSLFKLMSTCCRLLNDIRSYEREVEGGKPNALALYRVSSGGEMMMSKEAAISELERLIERQRRELMRTILEESVIPKCCKEIFGH", "output": "Involved in the biosynthesis of ent-kaurene diterpenoids natural products such as oridonin, miltiradiene, eriocalyxin B and nezukol, known to exhibit antitumor, anti-inflammatory and antibacterial activities . Catalyzes the conversion of ent-copalyl diphosphate (ent-CPP) to ent-isopimaradiene like compounds ."}]}
+{"id": "function_test_729", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSSTAVVHGDDLMEPTLQSILSQKTLRWIFVGGKGGVGKTTTSCSLAIQLAKVRKSVLLISTDPAHNLSDAFGQKFGKEARLVDGYSNLSAMEIDPNGSIQDLLASGESQGDDPMAGLGMGNMMQDLAFSIPGVDEAMSFAEVLKQVKSLSYEVIVFDTAPTGHTLRFLQFPTVLEKALAKLSQLSSQFGPMLNSILGARGGLPGGQNIDELLQKMESLRETISEVNTQFKNPDMTTFVCVCIAEFLSLYETERMIQELTSYGIDTHAIVVNQLLFPKEGSGCEQCNARRKMQKKYLEQIEELYEDFNVVRMPLLVEEVRGKEKLEKFSEMLVHPYVPPQ", "output": "ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting."}]}
+{"id": "function_test_730", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPPKAAEKKPSTGGKAPAGGKAPAEKKEAGKKTAAAASGDKKKRGKTRKETYSSYIYKVLKQVHPDTGISTRAMSILNSFVNDIFERVATEASKLAAYNKKSTISSREIQTSVRLILPGELAKHAVSEGTKAVTKYSSSAK", "output": "Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling."}]}
+{"id": "function_test_731", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSWQAYVDEHLMCEIEGHHLTSAAIVGHDGAVWAQSTAFPQFKTEEMTNIMKDFDEPGFLAPTGLFLGPTKYMVIQGEPGAVIRGKKGSGGITVKKTGQAMVVGIYDEPMTPGQCNMVVERLGDYLLNRA", "output": "Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity)."}]}
+{"id": "function_test_732", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MASAALIDADMAPTLQSILDQKTLRWIFVGGKGGVGKTTTSCSLAIQLAKHRKSVLLISTDPAHNLSDAFNQKFGKDARLVNGFDNLSAMEIDPNGSIQDLLASGAEEGQDPMAGLGGMGSMMQDLAFSIPGVDEAMSFAEVLKQVKSMSYEVIIFDTAPTGHTLRFLQFPTVMEKALSKVSQLSRQFGPMLNSFLGASGRLPNGQNMDELIEKMENLRETIGEVNGQFKDADLTTFVCVCIPEFLSLYETERMIQELNSYEIDTHSIVVNQLLFPKQDNPCEQCNARRKMQKKYLDQIEELYDEFNVVKMPLLVEEVRGKEKLEKFSEMLVKPFVPPQ", "output": "ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting."}]}
+{"id": "function_test_733", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEMASVFTLNVRLDNIAIITIDVPGEKMNTLKAEFASQVRAIIKQLRENKELRGVVFVSAKPDNFIAGADINMIGNCKTAQEAEALARQGQQLMAEIHALPIPVIAAIHGACLGGGLELALACHGRVCTDDPKTVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALEMILTGKQLRAKQALKLGLVDDVVPHSILLEVAVELAKKDRPSSRPLPVRERILAGPLGRALLFKMVGKKTEHKTQGNYPATERILEVVETGLAQGTSSGYDAEARAFGELAMTPQSQALRSIFFASTDVKKDPGSDAPPAPLNSVGILGGGLMGGGIAYVTACKAGLPVRIKDINPQGINHALKYSWDQLEGKVRRRHLKASERDKQLALISGTTDYRGFAHRDLIIEAVFENLELKQQMVAEVEQNCAAHTIFASNTSSLPIGDIAAHATRPEQVIGLHFFSPVEKMPLVEIIPHAGTSAQTIATTVKLAKKQGKTPIVVRDKAGFYVNRILAPYINEAIRMLTEGERVEHIDAALVKFGFPVGPIQLLDEVGIDTGTKIIPVLEAAYGERFSAPANVVSSILNDDRKGRKNGRGFYLYGQKGRKSKKQVDPAIYPLIGAQGQGRLSAPQVAERCVMLMLNEAVRCVDEQVIRSVRDGDIGAVFGIGFPPFLGGPFRYIDSLGAGEVVAIMQRLATQYGSRFTPCERLVEMGARGESFWKTTATDLQ", "output": "Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities."}]}
+{"id": "function_test_734", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAEFHPTAFLLPAAVTMIAGYFLCTALYNVYFHPLAKFPGPRLYAASQIPITIKRLLGDEVATFHKLHAKYGQFVRVAPGELSTINPAASRDVYGHRNPAKSIPKDFKAYYMKNQRRDGTEGLMTADDDLHRRQRKIFSPAFSDRAIREQEPLLKKYTDLLVEKAGVASDADGKVDMVMMFNFATFDFIADCVFGDSLHLLEKMEYNPFLANISAVVKFSAMRRAIRSFPYMDETFEKLIPASMKRKRMEHVKFCDDLVDRRLEKAVTNHPDFWTLVLRANEKGEGLTLGEMHQNSFLFLTAATETTSSLMSALTYLLCQNPDKMKKLVDEIRGRFKSTEEMTTVSLPPLEYLQMCIEEGLRVYPPVPGGLPRRVTADGASLDGRELPPDTVVYYAHYASYHSAAHFARPDEFHPERWASVPPSEFANDCRDAVIPFSAGPRDCIGKNLAYHEARLLLAKFLWTYDVELCEESKDWIKQKSFIVGVKRPLYVKLHRVVREK", "output": "Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of radicicol, a resorcylic acid lactone (RAL) that irreversibly inhibits the HSP90 molecular chaperone, an important target for cancer chemotherapy . The cluster encodes only two apparent post-PKS enzymes, a cytochrome P450 monooxygenase (radP) and a non-heme halogenase (radH) that introduce the epoxide and the chlorine, respectively . If this cluster includes all the genes required for radicicol biosynthesis, the remaining structural features of radicicol are presumably generated by the PKSs rads1 and rads2 . The C-2' ketone could arise if the R-PKS rads1 and NR-PKS rads2 each carry out four iterations, in contrast to the five iteration-three iteration split for the hypothemycin PKSs . The origin of the cis 5',6' double bond is not known (By similarity). The radicicol R-PKS rads1 ER domain may catalyze either double bond isomerization or reduction in the third iteration (By similarity)."}]}
+{"id": "function_test_735", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGSLQAMRRAQRAQGPATIMAVGTSNPPNLYEQTSYPDFYFRVTNSDHKHALKNKFRVICEKTKVKRRYLHLTEEILKQRPKLCSYMEPSFDDRQDIVVEEIPKLAKEAAEKAIKEWGRPKSEITHLVFCSISGIDMPGADYRLATLLGLPLSVNRLMLYSQACHMGAQMLRIAKDLAENNRGARVLAVSCEITVLSFRGPDAGDFEALACQAGFGDGAAAVVVGADPLPGVERPIYEIAAAMQETVPESERAVGGHLREIGWTFHFFNQLPKLIAENIEGSLARAFKPLGISEWNDVFWVAHPGNWGIMDAIETKLGLEQGKLATARHVFSEYGNMQSATVYFVMDEVRKRSAAEGRATTGEGLEWGVLFGFGPGLTIETVVLRSVPLP", "output": "Catalyzes the synthesis of curcumin by condensing feruloyl-CoA with a diketide-CoA in the curcuminoid biosynthesis. Also acts as a demethoxycurcumin synthase by accepting 4-coumaroyl-CoA as a starter substrate instead of feruloyl-CoA."}]}
+{"id": "function_test_736", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSQFAREIVRNAIYNTSSPDADSVSLRKATTTILLIGVTYCILVGIYRVTLHPLAKYPGPKLAAVTRLWHSYHLCTGDIVSVLSRAHEAYGPVLRIAPDEVLFISSRAWDDIYGARPGKPEMDKDTPLYKGPTAPHSIVTVDGELHRFYRRLLAKGFSDAALREQEPVIQRNINLLVEKLHKEVAAGKTPEMTAWFNYATFDLIGELAFGETYGCLENSHYHPWVEMILEVMKLRAMTHAVGYYPWIFHILMWFVPKSLREKFVTHRRYTHDKVQRRMDQKIHYKDLTTNLVDPQNGLERYEIDGNCSTLIIAGSETTATALSATLYFLTQNENAKRKVIGEIRTTFNNAGDINSISVNQLKYLSACMNEALRIFPPGPAVFPRRVPQGGDFIDGHWIPGGTQVGIAHYCINRSRRNFVDPDKFIPERWLGDPTYQTDDRHAVQPFSYGPRNCIAHNLARLEMRLVLARLIWEFDWELAPGSERWEEEALVFNVWSTKPLMIKFTPVAR", "output": "Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the fungal neurotoxin cyclopiazonic acid (CPA), a nanomolar inhibitor of Ca(2+)-ATPase with a unique pentacyclic indole tetramic acid scaffold . The hybrid two module polyketide synthase-nonribosomal peptide synthetase (PKS-NRPS) cpaS incorporates acetyl-CoA, malonyl-CoA, and tryptophan (Trp) and utilizes a C-terminal redox-incompetent reductase domain to make and release the tryptophan tetramic acid, cyclo-acetoacetyl-L-tryptophan (c-AATrp), as the first intermediate in the pathway. CpaS catalyzes a Dieckmann-type cyclization on the N-acetoacetyl-Trp intermediate bound in thioester linkage to the phosphopantetheinyl arm of the T domain to form and release c-AATrp . CpaD then regiospecifically dimethylallylates c-AATrp to form beta-cyclopiazonic acid. CpaD discriminates against free Trp but accepts tryptophan-containing thiohydantoins, diketopiperazines, and linear peptides as substrates for C4-prenylation and also acts as regiospecific O-dimethylallyltransferase (DMAT) on a tyrosine-derived tetramic acid . The beta-cyclopiazonate dehydrogenase cpaO then carries out the dehydrogenation of beta-CPA to yield an unstable enimine product, which is captured by intramolecular cyclization to create the pentacyclic fused scaffold of alpha-cyclopiazonate . Finally, the cytochrome P450 monooxygenase cpaH mediates the conversion of CPA into the less toxic 2-oxocyclopiazonic acid, the end product of the CPA pathway in A.oryza ."}]}
+{"id": "function_test_737", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQEFEFAVPAPSRVSPDLARARARHLDWVHAMDLVRGEEARRRYEFSCVADIGAYGYPHATGADLDLCVDVLGWTFLFDDQFDAGDGRERDALAVCAELTDLLWKGTAATAASPPIVVAFSDCWERMRAGMSDAWRRRTVHEWVDYLAGWPTKLADRAHGAVLDPAAHLRARHRTICCRPLFALAERVGGYEVPRRAWHSSRLDGMRFTTSDAVIGMNELHSFEKDRAQGHANLVLSLVHHGGLTGPEAVTRVCDLVQGSIESFLRLRSGLPELGRALGVEGAVLDRYADALSAFCRGYHDWGRGASRYTTRDHPGDLGLENLVARSSG", "output": "In vitro, catalyzes the formation of R-linalool from geranyl diphosphate (GPP). Can also accept farnesyl diphosphate (FPP) as substrate to produce trans-nerolidol."}]}
+{"id": "function_test_738", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKYTILSLVAGALISCSAMAENTLTVKMNDALSSGTGENIGEITVSETPYGLLFTPHLNGLTPGIHGFHVHTNPSCMPGMKDGKEVPALMAGGHLDPEKTGKHLGPYNDKGHLGDLPGLVVNADGTATYPLLAPRLKSLSELKGHSLMIHKGGDNYSDKPAPLGGGGARFACGVIEK", "output": "Destroys radicals which are normally produced within the cells and which are toxic to biological systems."}]}
+{"id": "function_test_739", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAKSTFFVCLNLSLLFSLVTATYYSSLTPTLLGFREEQFTHLHFFFHDVVTGPKPSMVFIAEPNGKAKDALPFGTVVAMDDPLTVGPEQDSKLVGKAQGIYTSISQEEMGLMMVMTMAFTDGDFNGSTISVLGRNMIMSEPVREMAIVGGTGAFRFARGYAQARFYSVDFTKGDAIVEYDVFVNHY", "output": "Involved in pterocarpan phytoalexin biosynthesis . Catalyzes the last step in the biosynthesis of the phytoalexin medicarpin, and thereby contributes to plant defense reactions . Dirigent proteins impart stereoselectivity on the phenoxy radical-coupling reaction, yielding optically active lignans from two molecules of coniferyl alcohol in the biosynthesis of lignans, flavonolignans, and alkaloids and thus plays a central role in plant secondary metabolism (By similarity)."}]}
+{"id": "function_test_740", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLVFYALLFVTVFSNTVMGATIDKPIPKPILREAIEEIEVNKRAQNHYCKEHNCPPGKHCPKVPIACVYGPCCF", "output": "Toxin that inhibits voltage-gated potassium channel currents in DRG neurons (IC(50)=about 570 nM). In vivo, induces neurotoxicity shown by twitching, paralysis, and body contraction. In vivo, insects injected with this toxin showed signs of neurotoxicity including twitching, paralysis, and body contraction."}]}
+{"id": "function_test_741", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MALPSSSLSSQIHTGATTQCIPHFHGSLNAGTSAGKRRSLYLRWGKGPSKIVACAGQDPFSVPTLVKREFPPGFWKDHVIESLMPSYKVAPSDEKRIETLITEIKNMFRSMGYGETNPSAYDTAWVARIPAVDGSEKPQFPETLEWILQNQLKDGSWGEEFYFLAYDRILATLACIITLTIWQTGDTQVQKGIEFFKTQAGKIEEEADSHRPSGFEIVFPAMLKEAKALGLALPYELPFIQQIIEKREAKLQRLPSDLLYALPTTLLYSLEGLQEIVDWEKIMKLQSKDRSFLSSPSSTAAVFMRTGNKKCLEFLNFVLKKFGNHVPCHYPLDLFERLWAVDTVERLGIDHHFKEEIKDALDYVYSHWDERGIGWARENPVPDIDDTAMGLRILRLHGYNVSSDVLKTFRDENGEFFCFLGQTQRGVTDMLNVNRCSHVAFPGETIMEEAKLCTERYLRNALEDTGAFDKWALKKNIRGEVEYALKYPWHRSMPRLEARSYIENYGPNDVWLGKTMYMMPNISNEKYLELAKLDFNRVQFFHRQELQDIRRWWNSSGFSQLGFTRERVAEIYFSPASFLFEPEFATCRAVYTKTSNFTVILDDLYDAHGTLDNLKLFSESVKRWDLSLVDQMPQDMKICFKGFYNTFNEIAEEGRKRQGRDVLSYIQKVWEVQLEAYTKEAEWSAVRYVPSYDEYIENASVSIALGTVVLISALFTGEILTDDILSKIGRDSRFLYLMGLTGRLVNDTKTYQAERGQGEVASAVQCYMKDHPEISEEEALKHVYTIMDNALDELNREFVNNRDVPDTCRRLVFETARIMQLFYMDGDGLTLSHNMEIKEHVKNCLFQPVA", "output": "Involved in defensive oleoresin formation in conifers in response to insect attack or other injury. Involved in diterpene (C20) olefins biosynthesis. Bifunctional enzyme that catalyzes two sequential cyclizations of geranylgeranyl diphosphate (GGPP) to levopimaradiene. Levopimaradiene is the major products of the enzyme with abietadiene and neoabietadiene. No activity with farnesyl diphosphate (FPP) as substrate."}]}
+{"id": "function_test_742", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MYDVVVVGAGPAGSMAAKTAAEQGLKVLLVEKRQEIGTPVRCAEGISRESIEKFFEVDKKWIAAEVTGAKIYAPNKTEIVMSEEMAGNEVGYVLERKIFDRHVARLAAKAGAEVYVKTAMVDFERKDGKVKVKLRRLGEDWEVETKILIGADGVESKIGRKAGIIKTLKLNEVESCAQYLMTGLDIDESYTYFYLGRELAPGGYAWIFPKGNGSANVGIGVLPKMAERTAKEYLDAFIEKEGIEGKIVEFVAGAVPVYGEIETAVADNIMLAGDAAYHADPITGGGIANALSAGYYAGKVAAEAVQKNDFSADFLRRYDELWKNDFGKKLRRNKKLQLKFIDMDDALLNKLAGAIAGKNLREMSVAAIVKELLKAHPKLLWDLKDLF", "output": "Is involved in the reduction of 2,3-digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. Is not active with NADPH as an electron donor. Is not able to reduce the prenyl group of respiratory quinones."}]}
+{"id": "function_test_743", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIAMDIREIGLRLVGEAIKAADPYRAVLNAVKVSDDKIIVQGKEFEIKGKVYVIALGKAACEMARAIEDILDVEDGVAVTKYGYGKELKRIKVIEAGHPIPDEKSILGAKEALSILNRARENDIVFILISGGGSALFELPEEGISLEDLKLTTDLLLKSGAKIHEINTVRKHISKVKGGKLAKMIKGTGIVLIISDVVGDNLEAIASGPTVKDPTTFEDAKRILELYDIWEKVPESVRLHIERGLRGEVEETLKEDLPNVHNFLIASNSISCEAIAREAQRLGFKAYIMTTTLEGEAKDAGLFIGSIVQEIAERGRPFEPPVVLVFGGETTVTIEGKGGKGGPNQEIALSATRKISDLEALIVAFDTDGTDGPTDAAGGIVDGTTYKKLREKGIDVEKVLKEHNSYEALKKVGGLLFTGPTGTNVNSIVIAIVTSKRGRT", "output": "Catalyzes the ATP-dependent phosphorylation of D-glycerate to 2-phosphoglycerate. It can also utilize GTP, CTP, UTP, ADP or pyrophosphate as phosphate donor."}]}
+{"id": "function_test_744", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEFVTNYTLEELKKRFTELGLEPYRAKQVFRWVYKKFVTDFEKMTDLGKKHRELLKEHFAFHPLEKLDRVEAPDAVKYLFKTKDGHILETVLIKERDHYTLCVSSQIGCAVGCTFCATALDGLKRNLSTAEIIDQYLQVQQDLGEEKIRNVVFMGMGEPLANYENVRKAVEIMVSPEGLDLSKRRITISTSGIVAQIKRMAQDPVMKEVNLAVSLNAVSQKKREELMPLTKTNTLEELMEVLKNYPLPKYRRITLEYVLIKGVNDSPNDAERLAKLIGRHKKKFKVNLIPFNPDPNLPYERPALTDIMKFQKVLWKYGISNFVRFSKGVEVFGACGQLRTQRLQLQRV", "output": "Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs."}]}
+{"id": "function_test_745", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIRRVRVTVRVSRACRPHHVRIFVAKIVQALCRASASINQGTPFQVLLIVRKKRHRGRSGHDDGQCTPGSNPVAVRGGTQHPRPDNPHPASPRRCPGGLPGHSDAAPSGRGAAGCQGLLGSPACGPRRGTRTPPRGRIPARGGEGRLNDTVQEAQ", "output": "Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus. This inhibits the oncogenic action of MDM2 by blocking MDM2-induced degradation of p53 and enhancing p53-dependent transactivation and apoptosis. Also induces G2 arrest and apoptosis in a p53-independent manner by preventing the activation of cyclin B1/CDC2 complexes. Binds to BCL6 and down-regulates BCL6-induced transcriptional repression. Binds to E2F1 and MYC and blocks their transcriptional activator activity but has no effect on MYC transcriptional repression. Binds to TOP1/TOPOI and stimulates its activity. This complex binds to rRNA gene promoters and may play a role in rRNA transcription and/or maturation. Interacts with NPM1/B23 and promotes its polyubiquitination and degradation, thus inhibiting rRNA processing. Plays a role in inhibiting ribosome biogenesis, perhaps by binding to the nucleolar localization sequence of transcription termination factor TTF1, and thereby preventing nucleolar localization of TTF1 (By similarity). Interacts with COMMD1 and promotes its 'Lys63'-linked polyubiquitination. Interacts with UBE2I/UBC9 and enhances sumoylation of a number of its binding partners including MDM2 and E2F1. Binds to HUWE1 and represses its ubiquitin ligase activity. May play a role in controlling cell proliferation and apoptosis during mammary gland development (By similarity)."}]}
+{"id": "function_test_746", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSHIQRETSCSRPRLNSNLDADLYGYKWARDNVGQSGATIYRLYGKPDAPELFLKHGKGSVANDVTDEMVRLNWLTEFMPLPTIKHFIRTPDDAWLLTTAIPGKTAFQVLEEYPDSGENIVDALAVFLRRLHSIPVCNCPFNSDRVFRLAQAQSRMNNGLVDASDFDDERNGWPVEQVWKEMHKLLPFSPDSVVTHGDFSLDNLIFDEGKLIGCIDVGRVGIADRYQDLAILWNCLGEFSPSLQKRLFQKYGIDNPDMNKLQFHLMLDEFF", "output": "Resistance to kanamycin and structurally-related aminoglycosides, including amikacin."}]}
+{"id": "function_test_747", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGITMDEEVIFETPRELISIKRIKDIPRSKDTHVFAACITSDGYPLIGARRTSFAFQAILSQQNSDSIFRVSTKLLRFMYYNELREIFRRLRKGSINNIDPHFEELILLGGKLDKKESIKDCLRRELKEESDERITVKEFGNVILKLTTRDKLFNKVYIGYCMACFINQSLEDLSHTSIYNVEIRKIKSLNDCINDDKYEYLSYIYNMLVNSK", "output": "Decapping enzyme that remove the protective 5'-cap from both host and viral mRNAs to commit transcripts for decay by the cellular exonuclease XRN1 . Accelerates viral and cellular mRNA turnover to eliminate competing host mRNAs and allow stage-specific synthesis of viral proteins. Acceleration of the turnover of cellular transcripts may even promote the shutoff of host protein synthesis."}]}
+{"id": "function_test_748", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGASNNYHHGSNAQGSTAQQDSEETE", "output": "RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity). Plays a central regulatory role in the microbial response to space flight conditions. Is essential for virulence and is required for efficient invasion of non-phagocytic cells."}]}
+{"id": "function_test_749", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "HLLQFNKMIKFETRKNAIPFYAF", "output": "Snake venom phospholipase A2 (PLA2) that shows presynaptic neurotoxicity. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides."}]}
+{"id": "function_test_750", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDKKSLYKYLLLRSTGDMRRAKSPTIMTRVTNNVYLGNYKNAMNAPSSEVKFKYVLNLTMDKYTLPNSNINIIHIPLVDDTTTDISKYFDDVTAFLSKCDQRNEPVLVHCVAGVNRSGAMILAYLMSKNKESSPMLYFLYVYHSMRDLRGAFVENPSFKRQIIEKYVIDKN", "output": "Serine/tyrosine phosphatase which down-regulates cellular antiviral response by dephosphorylating activated host STAT1 and blocking interferon (IFN)-stimulated innate immune responses. Dephosphorylates the OPG144 protein."}]}
+{"id": "function_test_751", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MMQDATDPAVRAALQSQPSGLNSTDDWRQVMDRIMSLTARNPDAFRQQPQANRLSAILEAVVPARANPTHEKVLAIVNALAENRAIRPDEAGLVYDALLQRVARYNSGNVQTNLDRLVGDVREAVAQRERAQQQGNLGSMVALNAFLSTQPANVPRGQEDYTNFVSALRLMVTETPQSEVYQSGPDYFFQTSRQGLQTVNLSQAFKNLQGLWGVRAPTGDRATVSSLLTPNSRLLLLLIAPFTDSGSVSRDTYLGHLLTLYREAIGQAHVDEHTFQEITSVSRALGQEDTGSLEATLNYLLTNRRQKIPSLHSLNSEEERILRYVQQSVSLNLMRDGVTPSVALDMTARNMEPGMYASNRPFINRLMDYLHRAAAVNPEYFTNAILNPHWLPPPGFYTGGFEVPEGNDGFLWDDIDDSVFSPQPQTLLELQQREQAEAALRKESFRRPSSLSDLGAAAPRSDASSPFPSLIGSLTSTRTTRPRLLGEEEYLNNSLLQPQREKNLPPAFPNNGIESLVDKMSRWKTYAQEHRDVPGPRPPTRRQRHDRQRGLVWEDDDSADDSSVLDLGGSGNPFAHLRPRLGRMF", "output": "Structural component of the virion that acts as a cement protein on the capsid exterior and which mediates the interactions between the hexons, including the peripentonal hexons, and reaches all the way to the penton vertices. Two hexon linking proteins IIIa, one from each facet, stabilize the unique edge interface between a pair of facets. As the virus enters the host cell, hexon linking proteins IIIa are shed concomitant with virion acidification in the endosome. During virus assembly, seems to play a role in the serotype specificity of the packaging of viral DNA via its interaction with packaging protein 3."}]}
+{"id": "function_test_752", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEPSSKKVTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWIHRYGERILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLAKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNEDLWPLLLSVIFVPALLQCIVLPLCPESPRFLLINRNEENRAKSVLKKLRGNADVTRDLQEMKEESRQMMREKKVTILELFRSPAYRQPILSAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAACAVLMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAVAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPEELFHPLGADSQV", "output": "Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain (By similarity). In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors (By similarity)."}]}
+{"id": "function_test_753", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIIANVIRSFSLTLLIFAALLFRPAAAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVPLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDRSVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNSRQRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPVAALDKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGDNIFNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDRDEYRQASSGQYTAFNDAQSKQRGKENNDAMLNQDLLEIYPRQDTAAFRQVSAAIDAFNLGGNL", "output": "Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. Required for the translocation of pullulanase . This subunit forms the outer membrane channel (By similarity)."}]}
+{"id": "function_test_754", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPRPLAALLSTACILSFFIALFPRAASSRDILPLGSSLVVESYESSTLQSSDGTFSSGFYEVYTHAFTFSVWYSKTEAAAANNKTIVWSANPDRPVHARRSALTLQKDGNMVLTDYDGAAVWRADGNNFTGVQRARLLDTGNLVIEDSGGNTVWQSFDSPTDTFLPTQLITAATRLVPTTQSRSPGNYIFRFSDLSVLSLIYHVPQVSDIYWPDPDQNLYQDGRNQYNSTRLGMLTDSGVLASSDFADGQALVASDVGPGVKRRLTLDPDGNLRLYSMNDSDGSWSVSMVAMTQPCNIHGLCGPNGICHYSPTPTCSCPPGYATRNPGNWTEGCMAIVNTTCDRYDKRSMRFVRLPNTDFWGSDQQHLLSVSLRTCRDICISDCTCKGFQYQEGTGSCYPKAYLFSGRTYPTSDVRTIYLKLPTGVSVSNALIPRSDVFDSVPRRLDCDRMNKSIREPFPDVHKTGGGESKWFYFYGFIAAFFVVEVSFISFAWFFVLKRELRPSELWASEKGYKAMTSNFRRYSYRELVKATRKFKVELGRGESGTVYKGVLEDDRHVAVKKLENVRQGKEVFQAELSVIGRINHMNLVRIWGFCSEGSHRLLVSEYVENGSLANILFSEGGNILLDWEGRFNIALGVAKGLAYLHHECLEWVIHCDVKPENILLDQAFEPKITDFGLVKLLNRGGSTQNVSHVRGTLGYIAPEWVSSLPITAKVDVYSYGVVLLELLTGTRVSELVGGTDEVHSMLRKLVRMLSAKLEGEEQSWIDGYLDSKLNRPVNYVQARTLIKLAVSCLEEDRSKRPTMEHAVQTLLSADD", "output": "Probable receptor. Interaction with a ligand in the extracellular domain triggers the protein kinase activity of the cytoplasmic domain."}]}
+{"id": "function_test_755", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MARFHNPAERPYKLPDLCTTLDTTLQDITIACVYCRRPLQQTEVYEFAFSDLYVVYRDGEPLAACQSCIKFYAKIRELRYYSDSVYATTLENITNTKLYNLLIRCMCCLKPLCPAEKLRHLNSKRRFHKIAGSYTGQCRRCWTTKREDRRLTRRETQV", "output": "This protein may be involved in the oncogenic potential of this virus (cervical neoplasia-associated virus).; "}]}
+{"id": "function_test_756", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGSSKSKPKDPSQRRRSLEPPDSTHHGGFPASQTPDETAAPDAHRNPSRSFGTVATEPKLFWGFNTSDTVTSPQRAGALAGGVTTFVALYDYESWTETDLSFKKGERLQIVNNTEGDWWLAHSLTTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNPENPRGTFLVRKSETAKGAYCLSVSDFDNAKGPNVKHYKICKLYSGGFYITSRTQFGSLQQLVAYYSKHADGLCHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLEAKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVIEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERAYRMPCPPECPESLHDLMCQCWRKDPEERPTFKYLQAQLLPACVLEVAE", "output": "This phosphoprotein, required for both the initiation and the maintenance of neoplastic transformation, is a protein kinase that catalyzes the phosphorylation of tyrosine residues in vitro."}]}
+{"id": "function_test_757", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MASLPWSLTTSTAIANTTNISAFPPSPLFQRASHVPVARNRSRRFAPSKVSCNSANGDPNSDSTSDVRETSSGKLDRRNVLLGIGGLYGAAGGLGATKPLAFGAPIQAPDISKCGTATVPDGVTPTNCCPPVTTKIIDFQLPSSGSPMRTRPAAHLVSKEYLAKYKKAIELQKALPDDDPRSFKQQANVHCTYCQGAYDQVGYTDLELQVHASWLFLPFHRYYLYFNERILAKLIDDPTFALPYWAWDNPDGMYMPTIYASSPSSLYDEKRNAKHLPPTVIDLDYDGTEPTIPDDELKTDNLAIMYKQIVSGATTPKLFLGYPYRAGDAIDPGAGTLEHAPHNIVHKWTGLADKPSEDMGNFYTAGRDPIFFGHHANVDRMWNIWKTIGGKNRKDFTDTDWLDATFVFYDENKQLVKVKVSDCVDTSKLRYQYQDIPIPWLPKNTKAKAKTTTKSSKSGVAKAAELPKTTISSIGDFPKALNSVIRVEVPRPKKSRSKKEKEDEEEVLLIKGIELDRENFVKFDVYINDEDYSVSRPKNSEFAGSFVNVPHKHMKEMKTKTNLRFAINELLEDLGAEDDESVIVTIVPRAGGDDVTIGGIEIEFVSD", "output": "Catalyzes the oxidation of mono- and o-diphenols to o-diquinones."}]}
+{"id": "function_test_758", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "SVGFKAGVKDYKLTYYTPDYKTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEESQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPNAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLSHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHSGTVVGKLEGEREITLGFVDLLRDDFVEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLASEGNQIIREASKWSPELAAACEVWKE", "output": "RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site."}]}
+{"id": "function_test_759", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "SVAFSRAVLAEFLATLIFVFFGLGSALSWPQALPSVLQIALAFGLAIGTLVQALGHVSGAHINPAVTVACLVGCHVSFLRAAFYVAAQLLGAVAGAAILHEITPPDVRG", "output": "Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient."}]}
+{"id": "function_test_760", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSAPDSITVTVADHNGVAVLSIGGEIDLITAAALEEAIGEVVADNPTALVIDLSAVEFLGSVGLKILAATSEKIGQSVKFGVVARGSVTRRPIHLMGLDKTFRLFSTLHDALTGVRGGRIDR", "output": "Positive regulator of sigma-F (SigF) activity. Binds to anti-sigma-F factor RsbW (UsfX) preventing its binding to SigF, thus activating transcription."}]}
+{"id": "function_test_761", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAFPEYSPAASAATFADLQIHPRVLRAIGDVGYESPTAIQAATIPALMAGSDVVGLAQTGTGKTAAFAIPMLSKIDITSKVPQALVLVPTRELALQVAEAFGRYGAYLSQLNVLPIYGGSSYAVQLAGLRRGAQVVVGTPGRMIDHLERATLDLSRVDFLVLDEADEMLTMGFADDVERILSETPEYKQVALFSATMPPAIRKLSAKYLHDPFEVTCKAKTAVAENISQSYIQVARKMDALTRVLEVEPFEAMIVFVRTKQATEEIAEKLRARGFSAAAISGDVPQAQRERTITALRDGDIDILVATDVAARGLDVERISHVLNYDIPHDTESYVHRIGRTGRAGRSGAALIFVSPRELHLLKAIEKATRQTLTEAQLPTVEDVNTQRVAKFADSITNALGGPGIELFRRLVEEYEREHDVPMADIAAALAVQCRGGEAFLMAPDPPLSRRNRDQRRDRPQRPKRRPDLTTYRVAVGKRHKIGPGAIVGAIANEGGLHRSDFGQIRIGPDFSLVELPAKLPRATLKKLAQTRISGVLIDLRPYRPPDAARRHNGGKPRRKHVG", "output": "DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation."}]}
+{"id": "function_test_762", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNPNQKIITIGSASLGLVFLNVILHVVSITVTVLVLSNNVTGPNCNGTIIREYNGTVRIERITQWYNTNIIEYIERPSNEYYMSNTEPLCEAQGFAPFSKDNGIRIGSKGHVFVIREPFVSCSPLECRTFFLTQGSLLNDKHSNGTVKDRSPYRTLMSVEVGQSPNVYQARFEAVAWSATACHDGKKWMTVGVTGPDAQAVAVVHYGGVPVDVINSWAGNILRTQESSCTCIKGDCYWVMTDGPANRQAQYKIFKAKDGRIIGQTDVNFNGGHIEECSCYPNEGKVECVCRDNWTGTNRPVLVISPDLSYTVGYLCAGIPTDTPRGEDSQFTGSCTKPLGNQGYGIKGFGFRQGNDVWAGRTISRTSRSGFEIIKIRNGWTQNSKDQIRKQVIVDNLNWSGYSGSFTLPVELTKKGCLVPCFWVEMIRGKPEEITIWTSSSSIVMCGVDHKVASWSWHDGAILPFDIDKM", "output": "Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates. Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release. Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface. These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell. Otherwise, infection would be limited to one round of replication. Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors. May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells. Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport. May additionally display a raft-association independent effect on budding. Plays a role in the determination of host range restriction on replication and virulence. Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication."}]}
+{"id": "function_test_763", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MCAARLAAAAAQSVYAFSARPLAGGEPVSLGSLRGKVLLIENVASLUGTTVRDYTQMNELQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGGFEPNFMLFEKCEVNGAGAHTLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNFEKFLVGPDGVPLRRYSRRFQTIDIEPDIEALLSQGPSCA", "output": "Protects the hemoglobin in erythrocytes from oxidative breakdown. In platelets, plays a crucial role of glutathione peroxidase in the arachidonic acid metabolism."}]}
+{"id": "function_test_764", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MYLVTAAEMGQLDRLASSEYMIPSIVLMENAGLRVVESIERHFQGQVANRRILIFCGKGNNGGDGLVVARHLLNRGAEVKVFLLARPEDIRGDARTNLEIYQKMGGKLLLLLGESHLQRADIALLYADLVVDAIFGTGFKGAAMGLPAAVINMINKAHRETVAVDLPSGLEADTGRCFGPCIQATWTVTFALPKLGLVVEPGASLTGRLEVADIGIPQKLVATQHFNRRLLTAAWCRSQLPRREASGHKGLYGRVLAVGGSPGLTGAITLAATAALKAGAGLVTAAVPRGVQGILAMKTTEIMTMSLPETPAGALSRDALDPLLERLAEVDVLAIGPGLSRDPATVDLVKELLPRVQVPAVVDADALNALATDTRVLTGDHGPLVLTPHPGEMARLLGTTAAKIQEDRLEIAAKYAREWQAVLLLKGARTVIAWPDGQVYINPTGNPGMATAGSGDVLTGIIAGLAGQGLKPGVAAALGAYLHGAAGDEAARQRGQRAMMAGDLLDFLPYVLRNLEEEVETIVAAGLGRD", "output": "Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)."}]}
+{"id": "function_test_765", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MYPPEFSYVRAESLQEALKFLEGNDNTRPLAGGQSLIPMLKLRVLSPDYILDINRLNELNYVKTSLNGVSIGALTRYHDILSNDIVKSKVPLMHHATRTIGDMQVRNMGTIGGAISNADPASDMPVVLTALNATIILSSASGSRSVKALDFFKGPFTTDTNKGELVTQIEVPVLDGYKTVYKKVVRRAGDYALASVALAIKLKGNEIEDIKLAYGGVHDKPFRAMEVEKNVIGKKLNDDLVKDIASKVSSQINPPSDHRGSSWYRREVVKVLTMKAFKEVA", "output": "Component of the glyceraldehyde dehydrogenase which is involved the nonphosphorylated Entner-Doudoroff pathway. Catalyzes the oxidation of D-glyceraldehyde to yield glycerate. When the artificial electron acceptor 2,6-dichlorophenol-indophenol (Cl2Ind) is used, the enzyme shows a broad substrate range (glyceraldehyde-3-phosphate, formaldehyde, acetaldehyde, propionaldehyde and isobutyraldehyde), but is most active with D-glyceraldehyde. It is not known which acceptor is utilized in vivo."}]}
+{"id": "function_test_766", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSGSYPFIDIAALDSVREGFARGDAQLVLAHDLSTVLWVNGPGAKLFGYNRVEDLIEGQLDLPVATRRQIAAFSSENTSAPSAVAVRLGGGLRSELTHLHVSNIKLPDGVAALLVATQMPDNSAEAAISGLGDDSTHIALVDAVGKVVAASPRFALLDISASTLEDLIVEAGDATDRIVKRRIRTGSHSVPGAIARLTDTPALHLLCIVGDAPAQFQTAAEAVPLPDNAEAVLEEILPEQGDAPAQQAQKTHAEQPRPKTFAFDHDAPPARFIWKVGPDGTFSEISPNLAAVVGPNSADIVGRRFSDVANVFGFDTDGSIAALLLERDTWSGKRLLWPVEGTRLRVPVELAALPVYSRDREFLGFRGFGIVRPAEAEADPEEIGLALAGGIPQNRKPRKEPAETARMVGEDDVLALSEEVANDDQPAAVLPKPPLDITPTPGRRDSDKVISLLNSCAQEKVAADQAKFLKEKERATRPEGGLTKTERNAFREIAERLRKQGLANTRAESETPVSETSSIEPVEPTPPVKTRSEPIQPDETALLANLPVPVIIHSGDAIHYVNQALLDITGYESLDDIRSAGGVDVLFNSESDDGETRQSMLLRHADGSEEPVDAHLNAIAWRGGRALMLSLMPVTAADLPAPAELPAANDEEKQALEAHVEELKTILDTATDGVVLIDPEGRIRSMNHSASALFGYERDEAEGKFFSMLFAIESQRAAMDYLHGLSGNGVLSVLNDGREVIGREAKGGFIPLFMTIGKLPHTRGFCAVLRDITQWKRTEEELTNARKEAERASNQKTEFLARISHEIRTPLNAIIGFSELMADEKFGPIGNDRYRDYLRDINRSGNHVLALVNDLLDISKIEAGALDMQFEAVSLNDAIGEAIALMQPQANRERVIIRSSFQSNLPDIVADSRSIKQVALNLLSNAVRFTAPGGQVIVSTSYELNGDVVMRVRDTGIGMSKSEVEQALKPFRQINALERRKAESAKDWRNEGTGLGLPLTKAMVEANRAQFAIDSNPGQGTVVEIVFPPTRVLAD", "output": "Functions as a polar differentiation marker. Essential protein that, by localizing in the old pole of dividing cells, controls cell division and maturation, probably through control of DivK phosphorylation status and cellular distribution, which in turn regulates CtrA, a transcriptional regulator of the minB operon. The asymmetrical localization of this protein is probably required for cells to enter a new division cycle."}]}
+{"id": "function_test_767", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSNPELSSEKKASLVETLKNKLQALAEQHVDVLESLAPVVRKRVDVLIEIQSQHDELEAKFLEEKSALEAKYHKLYGPLYSKRSEIVSGVLEVEGETEEREEKGVPDFWLKAMKNNEILAEEIHESDEEALKYLKDIKWCRIDDLKGFKFEFFFDTNPFFKNQVLTKTYHMIDEDDEPILEKAIGTEIEWHPGNCLTQEVLTKESLESTKPITKTEEYESFFNFFSPPQVPEDDAKIDENTVEELQNQMERDYDIASTLRDKIIPHAVSWFTGEAVQDEDYGASWVDDEEDDDDEYSDEEA", "output": "May modulate chromatin structure by regulation of nucleosome assembly/disassembly."}]}
+{"id": "function_test_768", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MATNESVSIFSSASLAVEYVDSLLPENPLQEPFKNAWNYMLNNYTKFQIATWGSLIVHEALYFLFCLPGFLFQFIPYMKKYKIQKDKPETWENQWKCFKVLLFNHFCIQLPLICGTYYFTEYFNIPYDWERMPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHPLETLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNLIPFYAGSRHHDFHHMNFIGNYASTFTWWDRIFGTDSQYNAYNEKRKKFEKKTE", "output": "Catalyzes the three-step monooxygenation required for the demethylation of 4,4-dimethyl and 4alpha-methylsterols, which can be subsequently metabolized to cholesterol."}]}
+{"id": "function_test_769", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAEYDLTTRIAHFLDRHLVFPLLEFLSVKEIYNEKELLQGKLDLLSDTNMVDFAMDVYKNLYSDDIPHALREKRTTVVAQLKQLQAETEPIVKMFEDPETTRQMQSTRDGRMLFDYLADKHGFRQEYLDTLYRYAKFQYECGNYSGAAEYLYFFRVLVPATDRNALSSLWGKLASEILMQNWDAAMEDLTRLKETIDNNSVSSPLQSLQQRTWLIHWSLFVFFNHPKGRDNIIDLFLYQPQYLNAIQTMCPHILRYLTTAVITNKDVRKRRQVLKDLVKVIQQESYTYKDPITEFVECLYVNFDFDGAQKKLRECESVLVNDFFLVACLEDFIENARLFIFETFCRIHQCISINMLADKLNMTPEEAERWIVNLIRNARLDAKIDSKLGHVVMGNNAVSPYQQVIEKTKSLSFRSQMLAMNIEKKLNQNSRSEAPNWATQDSGFY", "output": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins."}]}
+{"id": "function_test_770", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEDGHSKTVDEVLSHFRVDPERGLSLDQVKEYQKKYGPNELPAEEGKTLWQLVLEQFDDLLVKILLLAAIISFVLALFEEHEGVEAFVEPFVILLILIANAVVGVWQERNAESAIEALKEYEPEMGKVIRGDKSGVQKIRAKEIVPGDVVEVSVGDKIPADIRLIKIYSTTIRIDQSILTGESVSVIKHTDAVPDPRAVNQDKKNILFSGTNVAAGKARGVVIGTGLNTAIGKIRTEMSETEEIKTPLQQKLDEFGEQLSKVISLICVAVWAINIGHFNDPAHGGSWIKGAVYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVSRMFIFEKIEGNDSSFTEFEISGSTYEPIGEVTLNGQRIKAADYETLHELGTICIMCNDSAIDFNETKKVFEKVGEATETALIVLAEKLNPFNVAKQGLDRRSSAICVRQEIETKWKKEFTLEFSRDRKSMSSYCTPLKASKLGNGPKLFCKGAPEGVLERCTHARVGSTKVPLTQTLKQRILDLTRTYGTGRDTLRCLALATADSPMKPDDMDLNDSTKFYTYEVNLTFVGVVGMLDPPRKEVQDSIVRCRAAGIRVIVITGDNKATAEAICRRIGVFGEDEDTTGKSYSGREFDDLSVSEQREACSRARLFSRVEPAHKSKIVEFLQSMNEISAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVLADDNFSSIVAAVEEGRAIYNNMKQFIRYLISSNIGEVVSIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMTKPPRKADEGLISGWLFFRYMAIGGYVGCATVGGAAWWFMFSETGPQLSYWQLTHHLSCLGGGEEFKGIDCKIFNDPHPMTMALSVLVTIEMLNAMNSLSENQSLVQMPPWCNIWLIASMCLSFALHFVILYVDVLSTVFQVTPLDGNEWMTVMKFSLPVVLLDEILKFVARRISDGESYIKNMHGLVLAWAVFFAYIIWGP", "output": "This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium."}]}
+{"id": "function_test_771", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNPNQKIITIGSICMVIGIVSLMLQIGNIISIWVSHSIQTGNQHQAEPCNQSIITYENNTWVNQTYVNISNTNFLTEKAVASVTLAGNSSLCPISGWAVYSKDNGIRIGSKGDVFVIREPFISCSHLECRTFFLTQGALLNDKHSNGTVKDRSPYRTLMSCPVGEAPSPYNSRFESVAWSASACHDGTSWLTIGISGPDNGAVAVLKYNGIITDTIKSWRNNILRTQESECACVNGSCFTVMTDGPSNGQASYKIFKIEKGKVVKSVELNAPNYHYEECSCYPDAGEITCVCRDNWHGSNRPWVSFNQNLEYQIGYICSGVFGDNPRPNDGTGSCGPVSPNGAYGIKGFSFKYGNGVWIGRTKSTNSRSGFEMIWDPNGWTGTDSNFSVKQDIVAITDWSGYSGSFVQHPELTGVDCIRPCFWVELIRGRPKESTIWTSGSSISFCGVNSDTVGWSWPDGAELPFTIDK", "output": "Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates. Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release. Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface. These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell. Otherwise, infection would be limited to one round of replication. Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors. May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells. Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport. May additionally display a raft-association independent effect on budding. Plays a role in the determination of host range restriction on replication and virulence. Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication."}]}
+{"id": "function_test_772", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPPIPSLWIRVFFSWLLLSLPAAAAADFSHCGGCDDGDGGGGIWSTDNILQCQRVSDFLIAMAYFSIPLELLYFATCSDLFPLKWIVLQFGAFIVLCGLTHLITMFTYEPHSFHVVLALTVAKFLTALVSFATAITLLTLIPQLLRVKVRENFLRIKARELDREVGMMKRQEEASWHVRMLTHEIRKSLDRHTILYTTMVELSKTLELQNCAVWMPSESGSEMILTHQLRQMETEDSNSLSIAMDNPDVLEIKATKDAKVLAADSALGIASRGKLEAGPVAAIRMPMLKASNFKGGTPEVMETSYAILVLVLPEDGSLGWGEEELEIVEVVADQVAVALSHAAVLEESQLIREKLAAQHRDLLRAKHETTMATEARNSFQTAMYDGMRRPMHSILGLVSMMQQENMNPEQRLVMDAIVKTSSVASTLMNDVMQTSTVNREYLSLVRRAFNLHLLVKEAISVVRCLTGCKGIDFEFEVDNSLPERVVGDEKRVFHIVLHMVGTLIQRCNAGCLSLYVNTYNEKEERHNQDWMLRRANFSGSYVCVKFEIRIRESRGNLLSSSSSRRLQGPNSTSSEMGLSFNMCKKIVQMMNGNIWSVSDSKGLGETIMLALQFQLQHVTPVSGASSDLFRSAPIPNFNGLQVILVDSDDTNRAVTHKLLEKLGCLVLSVTSGIQCINSFASAESSFQLVVLDLTMRTMDGFDVALAIRKFRGNCWPPLIVALAASTDDTVRDRCQQAGINGLIQKPVTLAALGDELYRVLQNN", "output": "Ethylene receptor related to bacterial two-component regulators. Acts as negative regulator of ethylene signaling. May delay the transition from the vegetative stage to the floral stage by up-regulating GI (GIGANTEA) and RCN1 and cause starch accumulation in stems by down-regulating the alpha-amylase AMY3D."}]}
+{"id": "function_test_773", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIKLEQLVLASHNAGKLKELQAMLGASVKVRSIGEFSQVEPEETGLSFVENAILKARNAARLSGLPALADDSGLAVDFLGGAPGIYSARYADGRGDAANNAKLLEAMKDVPDAERGAQFVSVLALVRHADDPLPILCEGIWEGRILREARGAHGFGYDPLFWVPERDCSSAELAPEEKNRLSHRARAMALLKQRLGL", "output": "Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions."}]}
+{"id": "function_test_774", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDKLTDLNYTLNVITLINSTLHTILEDPGMAYFPYIASVLTVLFTLHKASIPTMKIALKTSKCSYKVVKYCIVTIFNTLLKLAGYKEQITTKDEIEKQMDRVIKEMRRHLEMIDKLTTREIEQVELLKRIYDKLMIRATDEIDMSKEINQKNVRTLEEWENGKNPYESKEVTAAM", "output": "Plays an essential role in the virus replication cycle by acting as a viroporin. Creates a pore in the host reticulum endoplasmic and as a consequence releases Ca(2+) in the cytoplasm of infected cell. In turn, high levels of cytoplasmic calcium trigger membrane trafficking and transport of viral ER-associated proteins to viroplasms, sites of viral genome replication and immature particle assembly.; "}]}
+{"id": "function_test_775", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAVDSSNSATGPMRVFAIGNPILDLVAEVPSSFLDEFFLKRGDATLATPEQMRIYSTLDQFNPTSLPGGSALNSVRVVQKLLRKPGSAGYMGAIGDDPRGQVLKELCDKEGLATRFMVAPGQSTGVCAVLINEKERTLCTHLGACGSFRLPEDWTTFASGALIFYATAYTLTATPKNALEVAGYAHGIPNAIFTLNLSAPFCVELYKDAMQSLLLHTNILFGNEEEFAHLAKVHNLVAAEKTALSTANKEHAVEVCTGALRLLTAGQNTGATKLVVMTRGHNPVIAAEQTADGTVVVHEVGVPVVAAEKIVDTNGAGDAFVGGFLYALSQGKTVKQCIMCGNACAQDVIQHVGFSLSFTSLPC", "output": "ATP-dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. It is a key purine metabolic enzyme in the opportunistic parasitic protozoan toxoplasma gondii as it cannot synthesize purines de novo."}]}
+{"id": "function_test_776", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDSPGGVTDKKRISSERRKEKSRDAARCRRSKESEVFYELAHQLPLPHTVSAHLDKASIMRLTISYLRMRKLLDAGELETEANMEKELNCFYLKALDGFVMVLSEDGDMIYMSENVNKCMGLTQFDLTGHSVFDFTHPCDHEELREMLTHRNGPVKKGKEQNTERSFFLRMKCTLTSRGRTVNIKSATWKVLHCTGHIRVYDTCNNQTHCGYKKPPMTCLVLICEPIPHPSNIEVPLDSKTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQVTTGQYRMLAKQGGYVWVETQATVIYNTKNSQPQCIVCVNYVLSGIVQKDLIFSLGQTECMLKPVESPEMKMTKIFSKDDWDDTNSLFEKLKQEPDALTVLAPAAGDTIISLDFSSNESDEQQCDEVPLYNDVMLPSSSEKLQNINIAMSPLPASETTKPLRSNADPALNREVVSKLEPNTETLELSFTMPQVQEQPTSPSDASTSQSSPEPSSPNDYCFDVDNDMANEFKLELVEKLFAIDTEAKNPFSTQETDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSSGSQNAATITILQQTQTPSTAADEIKPVAERVDDVKALIVPSSPVHVINDTSSAPASPYSGNRSRTASPIRAGKGTLEQTEKSCPGAPSLITVTLNKRSTAMDEELNPKMLALHNAQRKRKMEHDGSLFQAVGIGSLFQQTGDRGGNASLAWKRVKACKTNGHNGVEQKTIILLSTDIASKLLGQSMDESGLPQLTSYDCEVNAPIQGNRNLLQGEELLRALDQVN", "output": "Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease."}]}
+{"id": "function_test_777", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLQMHSNSSFSPKCYYPLQHAGCVKTLQLPLTKVHGGLNRSESKNYAIKCTQSDSFYSTNKIRNNENSSSRNCKPFNKYRVAVTLQQQDCASNNEDDINSTSFRDVLLKKLHALYVFTRPFAMIGTIVGITSIAILPLQSFADLTPKYFMEFLKALLSAVLMNNYVGTVNQVADVEIDKVNKPGLPLASGDLSVGTGLAITLILSLTSLAIALSLQSPPLIFGLIVWFLLGTAYSVDLPFLRWKTNPFLAGMCMVIVFGLVYQFSFFIHFQKYVLGRPVVITRPLIFAAAIISTISAVMSLLKDIPDEDGDKQFGYQSISSKLGKENVLRLCVYALFFAYGVAVIVGASSSFQLGKLVSIIGHSTLAFLLWLRAQTVDLSNNASTFSFYLFVWKLFYGEYLLIHFLR", "output": "Prenyltransferase specific for geranyl diphosphate as prenyl donor and coumarin as prenyl acceptor. Can use umbelliferone and esculetin as substrates, and with a lower activity, 5,7-dihydroxy-coumarin and 5-methoxy-7-hydroxycoumarin. No activity with 5-hydroxy-7-methoxycoumarin, bergaptol, xanthotoxol, p-coumaric acid, caffeic acid, 2,4-dihydroxycinnamic acid, kaempferol, genistein or homogentisate. No activity with dimethylallyl diphosphate, farnesyl diphosphate or geranylgeranyl diphosphate as prenyl donors."}]}
+{"id": "function_test_778", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTNAVEDSGPRDLLFLLISTSRFNRYMPYYTMMAAVWATFIAGALKLQQDPESLSIEFILYKAGLCFVHCLLLCGAGNTWNDLVDRDIDARVARTKMRPLASGKVTLTEALLWMTGQYFLSVKMLDLILDGRNIWTLMLPLTASIMLYPYLKRPIFSKVFVYPQYILGLAIGYPAITGWASITGSEEPLGDIIKHCIPICLLVFFWCVYFNTAYSHQDSVDDRKMNINSAYVIAGQRIRLFLAFLSVLPLLTIPYIISTINSPWLWVSWMATWTVSIVMQIAQFDSQKLESGGRIHWDNFLLGLWTIVACMVEVGLQKVEFWKNVEGYIKL", "output": "Polyprenyl transferase; part of the gene cluster that mediates the biosynthesis of mycophenolic acid (MPA), the first isolated antibiotic natural product in the world obtained from a culture of Penicillium brevicompactum in 1893 . MpaA' is a Golgi apparatus-associated enzyme that catalyzes the prenylation of 5,7-dihydroxy-4,6-dimethylphthalide (DHMP) to yield farnesyl-DHMP (FDHMP) . The first step of the pathway is the synthesis of 5-methylorsellinic acid (5MOA) by the cytosolic polyketide synthase mpaC. 5MOA is then converted to the phthalide compound 5,7-dihydroxy-4,6-dimethylphthalide (DHMP) by the endoplasmic reticulum-bound cytochrome P450 monooxygenase mpaDE. MpaDE first catalyzes hydroxylation of 5-MOA to 4,6-dihydroxy-2-(hydroxymethyl)-3-methylbenzoic acid (DHMB). MpaDE then acts as a lactone synthase that catalyzes the ring closure to convert DHMB into DHMP. The next step is the prenylation of DHMP by the Golgi apparatus-associated prenyltransferase mpaA to yield farnesyl-DHMP (FDHMP). The ER-bound oxygenase mpaB then mediates the oxidative cleavage the C19-C20 double bond in FDHMP to yield FDHMP-3C via a mycophenolic aldehyde intermediate. The O-methyltransferase mpaG catalyzes the methylation of FDHMP-3C to yield MFDHMP-3C. After the cytosolic methylation of FDHMP-3C, MFDHMP-3C enters into peroxisomes probably via free diffusion due to its low molecular weight. Upon a peroxisomal CoA ligation reaction, catalyzed by a beta-oxidation component enzyme acyl-CoA ligase ACL891, MFDHMP-3C-CoA would then be restricted to peroxisomes for the following beta-oxidation pathway steps. The peroxisomal beta-oxidation machinery than converts MFDHMP-3C-CoA into MPA_CoA, via a beta-oxidation chain-shortening process. Finally mpaH acts as a peroxisomal acyl-CoA hydrolase with high substrate specificity toward MPA-CoA to release the final product MPA  (Probable)."}]}
+{"id": "function_test_779", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAAAVVVRRAAGLIPLLSSRFGARMPLHRALSQIPPPRFCRLLSQQTKPFSASASNGAATDRTRELRLYNTKSRKKEQFRPRIPGREVGMYVCGVTPYDDSHIGHARAYVAFDVLYRYLRYLDYEVRYVRNFTDIDDKIIARANQLGEDPFSLSKRFSDDFLSDMANLQCLPPSVEPRVSDHVDEIINMIKQILDNRCAYVVGGDVYFSVDNFPEYGELSGRKLDDNRAGERVAVDERKRNPADFALWKAAKDGEPWWDSPWGPGRPGWHIECSAMSAHYLGHSFDIHGGGEDLIFPHHENEIAQSRAACCDSTINYWIHNGFVNVNSQKMSKSLGNFVTIRKVIEMYHPLALRMFLLGTHYRSPINYTIEQLNVASDRLYYTYQTLRDCEEICQHQQSNTGNPLPANTLNYIQKLHDEFETSMSDDLHTSVALAAMSEPLKVMNDLLHTRKGKKQDKRLESLSALEEKIRVVLSVLGLLPSSYHEALQQLRDKALRRASITEELVVQKIEERTAARKAKQYEKSDEIRKELAAVGIALMDGPDGTTWRPSLPLPEEEAVLAKT", "output": "Nuclear genome-encoded factor required for normal assembly of chloroplast polysomes."}]}
+{"id": "function_test_780", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGSNRLTARELCENDDLATSLVLDPYLGFRTHKMNVSAMPTIRRQHHLREALQTFCKKKDLEAAYQSLTAGGWARHYFHSRTRQQESLLKTHIFRYLRMFLPESGFMILSCSRYSLEMNGAKVVSTKSWSKNEKIELLVGCIAELSKADETLLRFGDNDFSVMYSTRKKCAQLWLGPAAFINHDCRPNCKFVPTEGNTACVKVLREIKTGEEITCFYGDSFFGEKNEMCECCTCERKGDGAFKQQNTEQTVSTSLEKYQLRETDGRLKRLSESACKPSPQVTTKKKGSKLRLSLRLKRIPASRRKGAFYRRVKTFASSRYFYKSHLMKHIPLKPVKIALPRGTVLRDVRIILHNCKKCNQASRPKSQHERQCCKLGKEPLVSLRREDLSPERLKFRLSCPGGSCPPIIQTANVGCNAKDCSQTEAGKSNLEQITTAELCEHLSFSPVPSHNEDDNSFYEPEIPGSLLGPESPSSEPLSNNLNLECNSPEPIVINTVYPHYNGGVTSDSHPHALKQFGITHYIQVDLRKDVTLEPGRSQPDKSSLEAEKKQIPNNKHSQHPVISDDHLVANLNAETQSNAVSPPTNTPICEALNGSLEHKVFSLRSRPVSFRPRKTSDNKITLFKRRRSSVKQGVRCVKLNGHVKLTGQLVPSKLHPPPGAGANHLTDAMHSDPKLLLKPYVELGLNNNLKRQSLTGLPPSTVLTGDAFNILHSPPASKQSTEGATKNVAFNPFTPSKRLRLVVSHGSIALDMASTSSEETS", "output": "Histone methyltransferase that specifically methylates monomethylated 'Lys-20' (H4K20me1) and dimethylated 'Lys-20' (H4K20me2) of histone H4 to produce respectively dimethylated 'Lys-20' (H4K20me2) and trimethylated 'Lys-20' (H4K20me3) and thus regulates transcription and maintenance of genome integrity. In vitro also methylates unmodified 'Lys-20' (H4K20me0) of histone H4 and nucleosomes (By similarity). H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5C is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity). Facilitates TP53BP1 foci formation upon DNA damage and proficient non-homologous end-joining (NHEJ)-directed DNA repair by catalyzing the di- and trimethylation of 'Lys-20' of histone H4 (By similarity). May play a role in class switch reconbination by catalyzing the di- and trimethylation of 'Lys-20' of histone H4 (By similarity)."}]}
+{"id": "function_test_781", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGRGKVELKRIENKISRQVTFAKRRNGLLKKAYELSLLCDAEVALIIFSGRGRLFEFSSSSCMYKTLERYRSCNYNSQDAAAPENEINYQEYLKLKTRVEFLQTTQRNILGEDLGPLSMKELEQLENQIEVSLKQIRSRKNQALLDQLFDLKSKEQQLQDLNKDLRKKLQETSAENVLHMSWQDGGGHSGSSTVLADQPHHHQGLLHPHPDQGDHSLQIGYHHPHAHHHQAYMDHLSNEAADMVAHHPNEHIPSGWI", "output": "Probable transcription factor involved in the development of floral organs. Required for the formation of inner floral organs (lodicules, stamens and carpels, or whorls 2, 3 and 4) and the lemma and palea (whorl 1), which are grass floral organs analogous to sepals. May be involved in the control of flowering time. Seems to act as transcriptional activator. May act upstream of the auxin-responsive protein GH3.8."}]}
+{"id": "function_test_782", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKVTLPEFERAGVMVVGDVMLDRYWYGPTSRISPEAPVPVVKVDTIEERPGGAANVAMNIASLGAHSRLVGLTGIDDAARALSKTLADVNVKCDFVSVPTHPTITKLRVLSRNQQLIRLDFEEGFEGVDPEPMHERIAQALGSIGALVLSDYAKGALASVQQMIQLARKAGVPVLIDPKGTEFERYRGATLLTPNLSEFEAVAGKCKNEEEIVERGMKIIADFDFSALLVTRSEQGMTLLQPGKPPLHMPTQAQEVYDVTGAGDTVIGVLAATLAAGNSLEEACYFANAAAGVVVGKLGTSTVSPIELENAVRGRADTGFGVMREDELKVAVAAARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGETRPVNPLEQRMIVLGALEAVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEQIAGSEEVWANGGDVMVLNFEDGCSTTNIIKKIQKDSQ", "output": "Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.; "}]}
+{"id": "function_test_783", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSNTKDVDADASNLLASLSVSKEKKEDTSNILAGLSLNGDESNKKEGSGVKDTESDKQKGNGKVEKVEKDENKDKSQSEAKDDSKRETNLIENRYEVEVKLDDIQADPNSPLYSVKSFEELGLKPELLKGLYAMKFNKPSKIQERALPLLISNPPKNMIGQSQSGTGKTAAFSLTMLSRVDESIKAPQCICLAPTRELARQTLEVVETMGKYSNITYQLVVPDSVPRGQAISAQVLVGTPGIVHDLINRKAINVAKVKVFVLDEADNMLDAQGLADTCLRVKKRLPRDCQLVLFSATFPTEVRKYAEKFVPNANSLALKQEELNVKGIKQLYMDCKNQEHKFEVLCELYGLLTIGSSIIFVEQKATADSLYLRMKEEGHTVSILHGGLEVADRDRLIDDFREGRSKVLITTNVLARGIDIATVSMVVNYDLPRTKEGRPDPSTYLHRIGRTGRFGRVGVSVSFVANEKDYQTLKYIAEYFGIEDQMTVVPTDDWDEVEKIVTRVIKEKKMT", "output": "ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. May also be involved in early transcription (By similarity)."}]}
+{"id": "function_test_784", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAEHDDGDLIAAIRGLARANVLVVGDLMLDRYAYGRVERISPEAPVPILTVTREIAMPGGAGNVVRNLTALDAAAAFVSVVGDDQEGSDLTALIGGQPNVEPWLLVETGRATTVKTRYIAAGQHLIRADRELVMPLTDKLGERLLKIASDAMAATSVTVLSDYRKGVLAPTIARNLIASARSIGRTVIVDPKGADWSHYAEADVITPNRRELAEAVGRDLPDEAAIVGAAREVIGRFGFGAVLCTRSEDGMSLVTVDTVRHYPAEAAEVYDVSGAGDTVVAVLAAGLASGLPLEIAARLSNIAGGLVVGKVGTAVARPDDLVDAVKPASGALRKVVTRQAAAEAAERWRQRGWRIGFTNGCFDLLHPGHVHLLEQARAGCDRLVVGLNADSSVRRLKGATRPVQPEAARAAVLASLASVDLVVIFEEDTPLDLLSAIRPDVLVKGADYTHDTVVGAREVESWGGRVMLAELLPGHSTTATVTRLRS", "output": "Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.; "}]}
+{"id": "function_test_785", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGALLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIREMYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR", "output": "Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine."}]}
+{"id": "function_test_786", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "NLFQFRKMIKKMTKKEPVVYYAFYGCYCGKGGRGKPKDATDRCCFVHDCCYEKVTGCNPKWGYYTYSMNKQIVCGGDDPCKKQVCECDKAAAICFRDNLKTYKKKYMSFPNFFCTDPSEKC", "output": "Snake venom phospholipase A2 (PLA2) that displays moderate myotoxic activity in vivo, and cytotoxic activity in vitro. In vitro, shows anticoagulant activity on human plasma and in mice causes inflammatory cell infiltration and myonecrosis in the gastrocnemius muscles of CD-1 mice 3 hours after injection (100 ug). PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides."}]}
+{"id": "function_test_787", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTRPIWMGDEPPPDRPPTLAGRGRLALRGGAMALVLMAGLTLHLAVRLIERPLHGGHRPWTPAITPVVCRICVAILGLRYSVRGRPMQHIGAVVANHTGWLDIFTLNACQRLYFVSKDEVADWPFIGWLARATGTVFIRRDPREAKAQQALLEDRIRDGHHLLFFPEGTSTDGLQVLPFKTTLFAAFYTHGLDKVMQIQPVTVNYTAPEGEDPRFYGWWRDMPFATHLAKVLSVARQGAAEVVFHPPLDVSDFPSRKDLAAACEAAVRSGMGQRSR", "output": "Catalyzes the second step in the formation of ornithine lipids, which are phosphorus-free membrane lipids (Probable). Uses acyl-acyl carrier protein (acyl-AcpP) as an acyl donor and converts lyso-ornithine lipid (LOL) into ornithine lipid (OL) (By similarity). It can also act as an alternate acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT) to ensure glycerophospholipid production ."}]}
+{"id": "function_test_788", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MCDDDVRALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGLMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAAASTSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETVYNSIMKCDVDIRKDLYANTVMSGGTTMYPGIADRMQKEITALAPSTIKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKEEYDESGPGIVHRKCF", "output": "Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.; "}]}
+{"id": "function_test_789", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKTTIILILLTHWVYSQNPTSGNNTATLCLGHHAVANGTLVKTITDDQIEVTNATELVQSTSIGKICNNPYRVLDGRNCTLIDAMLGDPHCDVFQYENWDLFIERSSAFSNCYPYDIPDYASLRSIVASSGTLEFTAEGFTWTGVTQNGRSGACRRGSADSFFSRLNWLTKSGNSYPTLNVTMPNNNNFDKLYIWGIHHPSTNNEQTKLYVQELGRVTVSTKRSQQTIIPNIGSRPGVRGQSGRISIYWTIVKPGDILMINSNGNLVAPRGYFKMRTGKSSIMRSDAPIDTCVSECITPNGSIPNDKPFQNVNKVTYGKCPKYIKQNTLKLATGMRNVPEKQIRGIFGAIAGFIENGWEGMVDGWYGFRYQNSEGTGQAADLKSTQAAIDQINGKLNRVIERTNEKFHQIEKEFSEVEGRIQDLEKYVEDTKIDLWSYNAELLVALENQHTIDLTDAEMNKLFEKTRRQLRENAEDMGNGCFKIYHKCDNACIGSIRNGTYDHYIYRDEALNNRFQIKGVELKSGYKDWILWISFAISCFLICVVLLGFIMWACQKGNIRCNICI", "output": "Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.; "}]}
+{"id": "function_test_790", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "DLVEFGFMIRCANRNSQPAWQYMDYGCYCGKRGSGTPVDDVDRCCQTHNECYDEAAKIPGCKPKWTFYFYQCGSGSQFTCRKSKDVCRNVVCDCDFKAALCLTGARYNSANYNIDIKTHCR", "output": "Snake venom oligomeric phospholipase A2 that has potent presynaptic neurotoxicity. Chain B is not itself neurotoxic, but it is essential for the neurotoxicity of textilotoxin. Subunit B possesses a very low phospholipase activity."}]}
+{"id": "function_test_791", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKILLAIALMLSTVMWVSTQQPQAVHTYCGRHLARTLADLCWEAGVDKRSGAQFASYGSAWLMPYSEGRGKRGIVDECCLRPCSVDVLLSYC", "output": "Brain peptide responsible for activation of prothoracic glands to produce ecdysone in insects."}]}
+{"id": "function_test_792", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEEAKSQSLEEDFEGQATHTGPKGVINDWRKFKLESEDSDSVPPSKKEILRQMSSPQSRDNKDSKERFSRKMSIQEYELIHRDKEDENCLRKYRRQCMQDMHQKLSFGPRYGFVYELETGEQFLETIEKEQKITTIVVHIYEDGIKGCDALNSSFTCLAVEYPMVKFCKIKASNTGARDRFSSDVLPTLLVYKGGELISNFISVSEQFAEEFFAGDVESFLNEYGLLPERETHALDQTNMEEDIE", "output": "Inhibits the transcriptional activation activity of the cone-rod homeobox CRX (By similarity). May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism."}]}
+{"id": "function_test_793", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MALDKLDLYVIIVLAVAVAAYFAKNQFLDQPQDTGFLSNDTAGGNSRDILETLKKNNKNTLLLFGSQTGTAEDYANKLSREIHSRFGLKTMVADFADYDWDNFGDIPNDILVFFIVATYGEGEPTDNADEFHTWLTDEADTLSTLRYTVFGLGNSTYEFYNAIGRKFDRLLEEKGGERFADYGEGDDGTGTLDEDFLTWKDNVFDTLKNDLNFEERELKYEPNVKLTERDDLTVDDSEVSLGEPNKKYIQSEEIDLTKGPFDHTHPYLAKISKTRELFASKERNCVHVEFDVSESNLKYTTGDHLAVWPSNSDENIAKFIKCFGLDDKINTVFELKALDSTYQIPFPNPITYGAVVRHHLEISGPVSRQFFLAIAGFAPDEETKKTFTRIGNDKQEFANKITRKKLNVADALLFASNGRPWSDVPFEFIIENVPHLQPRYYSISSSSLSEKQTINITAVVEVEEEADGRAVTGVVTNLLKNIEIEQNKTGEKPVVHYDLSGPRNKFNKFKLPVHVRRSNFKLPKNTTTPVILIGPGTGVAPLRGFVRERVQQVKNGVNVGKTVLFYGCRNEHDDFLYKQEWSEYASVLGENFEMFTAFSRQDPSKKVYVQDKIAENSKVVNDLLNEGAIIYVCGDASRMARDVQSTIAKIVAKHREIQEDKAVELVKSWKVQNRYQEDVW", "output": "This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis."}]}
+{"id": "function_test_794", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGVE", "output": "Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments."}]}
+{"id": "function_test_795", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLNQNSHFIFIILAIFLVLPLSLLSKNVNAQIPLRRHLLSHESEHYAVIFDAGSTGSRVHVFRFDEKLGLLPIGNNIEYFMATEPGLSSYAEDPKAAANSLEPLLDGAEGVVPQELQSETPLELGATAGLRMLKGDAAEKILQAVRNLVKNQSTFHSKDQWVTILDGTQEGSYMWAAINYLLGNLGKDYKSTTATIDLGGGSVQMAYAISNEQFAKAPQNEDGEPYVQQKHLMSKDYNLYVHSYLNYGQLAGRAEIFKASRNESNPCALEGCDGYYSYGGVDYKVKAPKKGSSWKRCRRLTRHALKINAKCNIEECTFNGVWNGGGGDGQKNIHASSFFYDIGAQVGIVDTKFPSALAKPIQYLNAAKVACQTNVADIKSIFPKTQDRNIPYLCMDLIYEYTLLVDGFGLNPHKEITVIHDVQYKNYLVGAAWPLGCAIDLVSSTTNKIRVASS", "output": "Catalyzes the hydrolysis of phosphoanhydride bonds of nucleoside tri- and di-phosphates."}]}
+{"id": "function_test_796", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MMLLGSPSSGGYGGKFAGASPAGGTTTMAPSAKQPSSRAPPPGITGGRNDLRILSPAAAAAAVGGLEMKKPEAEGIAESLQATHRKELEASIRKQLQGVELSPSPYDTAWVAMVPLRGSSHNPSFPQCVDWILENQWDDGSWSIDGSISTANKDVLSSTLACVLALNKWNVGREHIRRGLSFIGRNFSIAMDDQAVAPIGFGITFPAMLTLANGSGLEVPVRQNDIDSLNHLREMKIQREAGNHSRGRKAYMAYLAEGFGNLLEWDEIMMFQRKNGSLFNCPSSTAGALANYHDDKALQYLQSLVNKFDGVVPTLYPLNIYCQLSMVDALENMGISQYFASEIKSILDMTYSSWLGRDEEIMLDVTTCAMAFRLLRMNGYDVSSDELSHVAGASGFRDSLQGYLNDRKSVLEVYKTSKHSISENDLILDSIGSWSGSLLKEMLCSNGIQGTPGREEIEFALKYPFYSTLERLVHRKNIVLFDAKGSQMLKTECMPVHDSQDFLALAVDDFCISQSNYQNELNYLESWVKDNRLDQLHFARQKITYCYLSGAATTFRPEMGYARTSWARTAWLTAVIDDLFDVGGLEQEQENLLALMEKWEEPGEDEYYSEDVKIVFQALYNTVNEIGAKASALQGHDVTKYLVDVWLHVVRCMKVEAEWQRSQHLPTFEEYMESGMVSLGQGATVMSALFLIGEKLPEGVVELEEYDEMFRLMGTCGRLLNDIRGIEREESDGKMTNGVSLLVHASGGSMSVDEAKTEVMKRIDASRRKLLSLVVGEQEGPIPRPCKQLFWKMCKILHLFYYQTDGFSSPKEMVSAVDAVIKEPLQLRSL", "output": "Involved in phytocassane phytoalexins biosynthesis. Catalyzes the conversion of ent-copalyl diphosphate to the phytoalexin precursor ent-cassa-12,15-diene."}]}
+{"id": "function_test_797", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIRLQKFGEIVGTSRSWKLLSSTIAKRYSSSSNGVKEMTVRDALNSAMEEEMKRDDRVFLIGEEVAQYNGAYKISRGLLDKFGPKRVIDTPITEMGFTGLATGAAFAGLRPICEFMTFNFSMQAIDHIVNSAARTLYMSGGIQACPIVFRGPNGPAAAVAAQHSQHFAPWYGSIPGLKVVSPYSAEDARGLLKAAIRDPNPVVVLENEILYGKTFPISKEALSEDFVLPFGLAKVERPGKDITIVGESISVVTALEAADKLKADYGVEAEVINLRSIRPLDINTIAASVKKTNRIVTVDQAYSQHGIGSEIAAQIMESDAFDYLDAPVERVSMADVPMPYSHPVEAASVPNADVVVAAAKKCLYIK", "output": "The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3)."}]}
+{"id": "function_test_798", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSAILQYDSVSKGTYSVKPKPTESLGNEFSEGLFVPLIGGKEPIEYVKLRENLCTKVLNELEEITTHTTYDSNARVLRQLCEHASEPVDETGLLRTAIVCDKSSNSMHLKFYEQLKDDMEKIGWKNFVVLNLKAHRDLKSCFRVIKGGSFGLGVLSYDIEKLDEKTVLVLEDVEDCDRRLLSSLVEALSSLVRHSKLQGCLYTIFNLKIPLEMFDTSLDSKFLSNVKTKVFNMKASTEILESLFTSIEESLSLKFGWRTRRFFRSMFYERSWSVERVIECIRYSILTHFYGNALSIIEHLIYQKDFHLISPLHLTTLRTVPSFQRHIEQRLEIGDLESINYVEKMLNDDTYFQEMVIQMCENLLYRERLLRTQAKIWHELEMAVKTTTRISFADYLETFLQGDWLSSPQYKSICQAILRMNSTKALACLDYLNENIFTGNQTMKCLEIHQELSELIRNSSTNYLEPVEVRMQNYSGTKHTRKVVESGFDKSIIDFSKILKKIVGLLDEEVQYGCLGTESIDMYPFYEVLFYDYCRPLNQAFASGHQRSVIHSSCMDPEYYVGDEKKIDSEFSNAEKDGKDLISWLPDLSILYKLYSESGALLNLYDWYIAFSEHLQAGKENLKEDDNHPRESPQGNLQRELNELDEDKRKLEEAKLQSRFLFGLEELRFLGLIKPTARKTDHVMKTIYHQ", "output": "Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. ORC binds to multiple sites within the ars1 origin of DNA replication in an ATP-independent manner."}]}
+{"id": "function_test_799", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTESAAPSPRCVAAILLAGGRGLRAGFGRPKQLEWLCGKPVLRWSLDVLAGYPGLSGGVLVANHDVMAATYPLPEGWMAADPGVERQQSVANALSALTDWPDDAVVLVHDAARPGVDSAVVDRLLAALDGADAAIPVLPVPDTLVEAADGAAGAVVARDRLARVQTPQAFRLGTLRRAHAEASGAAATDDAQLVRSLGVSVATVEGDARLHKLTYAADMAILAGLLGTKDMMRTAVGMGYDVHRLVEGKPLWIGGIEIAHSHGLEGHSDADVGLHALTDAILGALGDGDIGDHFPPSDPQWRGAASHHFLSFAGERVAANGGRIGHLDLTIIAEAPRIGPHRVAIRDRIAEILAIPAGRVSVKATTTERLGFTGRREGIAAQAVATIQLPET", "output": "Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)."}]}
+{"id": "function_test_800", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLLWGRWKVVAGLAGLALSLELLLRYMRRRKPIREVLFFPAPVTCIEPVLYPMKQCSCPLPHTDSAFSRLLLLLLRAQRSLELCVFTFSCPSLARAVLLLHSRGVRVRVITDNDYMAASGSQIGPLRSAGVAVRHDQSSGYMHHKFAVVDGTVVLTGSLNWTVQATQTNRENILITDDRVIVKAYQQEFERLWQEYDPASYDFFPEKENK", "output": "Presents phospholipase and nuclease activities, depending on the different physiological conditions. Plays a key role in mitochondrial fusion and fission via its phospholipase activity. In its phospholipase role, it uses the mitochondrial lipid cardiolipin as substrate to generate phosphatidate (PA or 1,2-diacyl-sn-glycero-3-phosphate), a second messenger signaling lipid. Production of PA facilitates Mitofusin-mediated fusion, whereas the cleavage of PA by the Lipin family of phosphatases produces diacylgycerol (DAG) which promotes mitochondrial fission. Regulates mitochondrial shape through facilitating mitochondrial fusion. During spermatogenesis, plays a critical role in PIWI-interacting RNA (piRNA) biogenesis (By similarity). piRNAs provide essential protection against the activity of mobile genetic elements. piRNA-mediated transposon silencing is thus critical for maintaining genome stability, in particular in germline cells when transposons are mobilized as a consequence of wide-spread genomic demethylation. Has been shown to be a backbone-non-specific, single strand-specific nuclease, cleaving either RNA or DNA substrates with similar affinity (By similarity). Produces 5' phosphate and 3' hydroxyl termini, suggesting it could directly participate in the processing of primary piRNA transcripts (By similarity). Has been proposed to act as a cardiolipin hydrolase to generate phosphatidic acid at mitochondrial surface. Although it cannot be excluded that it can act as a phospholipase in some circumstances, this activity could not be confirmed (By similarity)."}]}
+{"id": "function_test_801", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAMETKSCQQLHIFFLPFMARGHSIPLTDIAKLFSSHGARCTIVTTPLNAPLFSKATQRGEIELVLIKFPSAEAGLPQDCESADLITTQDMLGKFVKATFLIEPHFEKILDEHRPHCLVADAFFTWATDVAAKFRIPRLYFHGTGFFALCASLSVMMYQPHSNLSSDSESFVIPNLPDEIKMTRSQLPVFPDESEFMKMLKASIEIEERSYGVIVNSFYELEPAYANHYRKVFGRKAWHIGPVSFCNKAIEDKAERGSIKSSTAEKHECLKWLDSKKPRSVVYVSFGSMVRFADSQLLEIATGLEASGQDFIWVVKKEKKEVEEWLPEGFEKRMEGKGLIIRDWAPQVLILEHEAIGAFVTHCGWNSILEAVSAGVPMITWPVFGEQFYNEKLVTEIHRIGVPVGSEKWALSFVDVNAETEGRVRREAIEEAVTRIMVGDEAVETRSRVKELGENARRAVEEGGSSFLDLSALVGELNDLAFGGLVE", "output": "Broad spectrum multifunctional glucosyltransferase. Catalyzes the formation of flavonol 3-O- and 4'-O-glucosides during fruit ripening. Accepted substrates include several flavonoids, hydroxycoumarins and beta-naphthols. Uses UDP-Glc as a sugar donor, but not UDP-Gal or UDP-GlcUA. May also be involved in detoxification of xenobiotics."}]}
+{"id": "function_test_802", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTELSALVERVEKLRGTMVLCVGDAMLDRFVYGSVERISPEAPIPVLCIERETAMLGGAGNVVRNLVAVGAEPAFVSVVGDDTAGREVTRLVGEHGEIDPCIVVEPGRQTTIKTRFFASHQQLLRADRESRSPVGEAIRAQLLTRIERLLPKAGVMVLSDYGKGVLAEPIAIELIRRAKAAGKQVIVDPKGTDYTIYAGATVVTPNRKELHEATGQAVDSDEQVVAAARQLIDSCGFEAVLVTRSQDGMTLVRADGQIDHLPAEAREVFDVSGAGDTVVATLAAALASGATLPEAAHLANVAAGIVVGKVGTAVAYGDELVVALHREDLTLGEAKIVPVTAAAEVVDRWRRKGQKVGFTNGCFDLLHPGHVSILAQAKGACDKLVVGLNSDASVQRLKGPTRPVQSEASRATVLSSLATVDLVVIFGEDTPLEVIGTLKPDVLVKGADYTIDKVVGADLVQSWGGKVVLAELVNGQSTTNTIKKMNGN", "output": "Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.; "}]}
+{"id": "function_test_803", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKLSMPRFDQAPVLVVGDVMLDRYWHGGTSRISPEAPVPVVKVEQIEDRPGGAANVALNIAALGAPASLVGVTGDDEAADSLSNSLKGAGVRALFQRIAHQPTIVKLRVMSRHQQLLRIDFEEPFATDALALGAQVDDLLEGIKVLVLSDYGKGALKNHQALIQAARAKGIPVLADPKGKDFSIYRGASLITPNLSEFEAIVGGCADEHELVTKGATLMHDLDLGALLVTRGEHGMTLLRPDHPALHLPARAREVFDVTGAGDTVISTLAAAIAAGEELPHAVALANLAAGIVVGKLGTAAISAPELRRAIQREEGSERGVLGLEQLLLAVADARAHNEKIVFTNGCFDILHAGHVTYLEQARAQGDRLIVAINDDASVSRLKGPGRPINSVDRRMAVLAGLGAVDWVISFAEGTPENLLREVKPDVLVKGGDYGIDQVVGADIVKAYGGAVKVLGLVENSSTTAIVEKIRKSE", "output": "Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.; "}]}
+{"id": "function_test_804", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTTTLERRESASFWEQFCAWITSTENRLYIGWFGCLMFPTLLSAISAYIIAFIAAPPVDIDGIREPVAGSLLYGNNIISGAVVPSSNAIGVHFYPIWEAASIDEWLYNGGTYQLVVLHFFIGVCAYIGREWELSYRLGMRPWICVAFSAPVAAAAAVFVIYPIGQGSFSDGMPLGISGTFNFMLVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRALHFFLGAWPVVGIWFTAMGVATMAFNLNGFNFNQSVVDSQGRVINTWADILNRSNLGMEVMHERNAHNFPLDLAAGESLPVALVAPAVAA", "output": "Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors."}]}
+{"id": "function_test_805", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPPKRNRNRLGTRGEGSGDSGVGMFERNDAVQEHKKEKIRLFMQDFVQQGKDRLAELKKDLESLSTTADKALEVELLKMPLAIRHMKVQDYLSLMGGDKSAVAAAAVKLDCSVDELSEPKLVRKNSKKVKVTTNVEYQDDVRTKVMTTSTKNRTVQKVPKSKSMLSLTGKNGKKTTALTRSVSATPLDKASKKLLVTNSSSKPAQRSSRTAMTPLTRSARSDTMFTFGDGAFLDEGVPFVKIPLADGKTVFSAGDDLDSLNVELLRGDTVQHIHNLVGQLTSLCAKASIQHHGNTL", "output": "Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Contributes to CPC function by facilitating loading of the CPC onto chromosomes."}]}
+{"id": "function_test_806", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MMQESATETISNSSMNQNGMSTLSSQLDAGSRDGRSSSDTSSEVSTVELLHLQQQQALQAARQLLLQQQTSGLKSPKNNEKQRPLQVPVSMAMMTPQVITPQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQPQPHPGKQAKEQQQLAAQQLVFQQQLLQMQQLQQQQHLLNLQRQGLISIPPSQSALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLTTNISSSTTSTTTSKASPPITHHSLLNGQASVLSARRDSSSHEETGASHTLYGHGVCKWPGCENICEDFGQFLKHLNNEHALDDRSTAQCRVQMQVVQQLEIQLSKERERLQAMMTHLHMRPSEPKPSPKPLNLVSTVTMSKNMLETSPQSLPQTPTTPTAPVTPLAQGPSVITPASVPNVGAIRRRHSDKYNIPMSSEIAPNYEFYKNADVRPPFTYATLIRQAIMESSDRQLTLNEIYSWFTRTFAYFRRNAATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEAEYQKRRSQKITASPTLVKNIPTSLGYGAALNASLQAALAESSLPLLSNTGLLNNASTGLLQAVHEDLNGSLDHIDSNGNSSAGCSPQPHIHSIHVKEEPLIADDEDCPMSLVTTANHSPELEEDRELEEEPLSEDLE", "output": "Transcriptional repressor."}]}
+{"id": "function_test_807", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGHSRRPAGGEKKSRGFGRSKAVADVGDGRQTGGKPQVKKATFESTKKKEIGVSDLTLLSKISNEAINDNLKLRFEHDEIYTYIGHVLVSVNPFRDLGIYTDNVLQSYRGKNRLEVPPHVFAVAESAYYNMKSYKDNQCVIISGESGAGKTEAAKRIMQYIASVSGGTDSSIQHTKDMVLATNPLLESFGNAKTLRNNNSSRFGKYLELEFNTNGEPVGANITNYLLEKSRVVGQITNERNFHIFYQFTKAAPQKYRDLFGIQQPQSYLYTSRSKCFDVPGVDDSAEFRDTLNAMNVIGMTEGEQDEVFRMLAAILWIGNVQFAEDDSGNAVITDQSVVDYVAYLLEVDAAQVNKAFTIRVMETARGGRRGSVYEVPLNTVQALAVRDALAKAIYFNLFDWIVQRVNASLTARGEVANSIGILDIYGFEIFEKNSFEQLCINYVNEKLQQIFIQLTLKAEQDEYAREQIQWTPIKYFDNKVVCSLIEDKRPPGVFAALNDACATAHADSSAADNTFVGRLNFLSQNPNFENRQGQFIIKHYAGDVSYAVAGMTDKNKDQLLKDLLNLVGTSGNQFVHTLFPEQVNQDDKRRPPTASDKIKASANDLVATLMKAQPSYIRTIKPNDNKAPREYNVGNVLHQIKYLGLQENVRIRRAGFAYRQTFDKFVERFYLLSPKTSYAGDYTWTGDAESGARQILKDTSIPAEEYQMGITKVFVKTPETLFALEAMRDRYWHNMAIRIQRAWRNYLRYRTECAIRIQRFWRRTTGGLEFIKLRDQGHQLLNGRKERRRMSLLGSRRFLGDYIGVGNKGGPGEMVRNGAGISGSEEILFSCRGEVLVSKFGRSSKPAPRILALTNRHVYIIAQNLVNNQLVISSERTIPIGAIKAVGASNLKDDWFSIVVGSPQEPDPLVNCVFKTEFFTHLNNALRGQLNLKIADHIEYNKKPGKLATVKVVKDPAVARDDSYKSGTIHTGPGEPANSVSKPTPRPKQVSARPVTKGKLLRPGGPGGGPSKLAARPTPAAQPLPRATPQPAEPQPAARAVPQPVAAVAASHTRTGSTASVRAPPPPPPAAAPAPKKPTAKVLYDFNSQQSNELSIKAGEIVQIVSKEGNGWWLCMNMTTSAQGWTPEAYLEEQVAPTPKPAPPPPPAAPRSTPAPATNGAAAAAKAKPAPPAPPAKRPNMAARKAVPTPPPAPRDSAVSMNSHDSSGGSGRGTPNSMSNASLAGGLAEALRARQHAMQGKQDDDDDW", "output": "Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex. Plays an important role in polarized growth, spore germination, hyphal morphogenesis, and septal wall formation (By similarity)."}]}
+{"id": "function_test_808", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRSSCVLLTALVALAAYYVYIPLPGSVSDPWKLMLLDATFRGAQQVSNLIHYLGLSHHLLALNFIIVSFGKKSAWSSAQVKVTDTDFDGVEVRVFEGPPKPEEPLKRSVVYIHGGGWALASAKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSAGGSLAAALGQQFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNTPILPRYVMVKYWVDYFKGNYDFVQAMIVNNHTSLDVEEAAALRARLNWTSLLPASFTKNYKPVVQTTGNARIVQELPQLLDARSAPLIADQAVLQLLPKTYILTCEHDVLRDDGIMYAKRLETAGVEVTLDHFEDGFHGCMIFTSRPTNFSVGIRTRNSYIKWLDQNL", "output": "Hydrolyzes 2-acetyl monoalkylglycerol ether (1-O-alkyl-2-acetyl-sn-glycerol), the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor (By similarity). May be responsible for the hydrolysis of cholesterol esters (such as cholesteryl (9Z-octadecenoate)) in macrophages (By similarity). Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds (By similarity)."}]}
+{"id": "function_test_809", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKRSKELITKNHSQEETSILRCWKCRKCIASSGCFMEYFENQVIKDKDDSVDAQNICHVWHMNIESLPEWISCLIQKAQWTVGKLNCPFCGARLGGFNFVSTPKCSCGQLAAVHLSKSRTDYQPTQAGRLMRPSVKYLSHPRVQSGCDKEVLLTGGGSKNRNHRLLNMARNNNDPGRLTEALCLEVRPTYFEMKNEKLLSKASEPKYQLFVPQLVTGRCTTRAFHRKSHSLDLNISEKLTLLPTLYEIRGKTTAYSRLNETQPIDLSGLPLQSSKNSCSFQNPSSFDPGMLLQRFSVAPHETQTQRGGEFQCGLEAASVYSDHTNTNNLTFLMDLPSAGRSMPEASDQEEHLSPLDFLHSANFSLGSINQRLNKRERSKLKNLRRKQRRRERWLQKQGKYSGVGFLDHMTLNNEMSTDEDNEYAEEKDSYICAVCLDVYFNPYMCYPCRHIFCEPCLRTLAKDNPSSTPCPLCRTIISRVFFQTELNNATKTFFTKEYLKIKQSFQKSNSAKWPLPSCRKAFHLFGGFHRHAAPVTRRQFPHGAHRMDYLHFEDDSRGWWFDMDMVIIYIYSVNWVIGFIVFCFLCYFFFPF", "output": "E3 ubiquitin-protein ligase which promotes polyubiquitination and degradation by the proteasome pathway of ZIC2."}]}
+{"id": "function_test_810", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAAVIVLAAGGGTRMKSTKSKLLHEVAGRPMLSWAIGAARGLNPEHLVVVVGHRREQVEAHLAEDAPDVTTAVQAEQKGTGHAVACGLEGLDELHGEVVVTYGDVPMLTGETLQRMVEVHRERRNLVTVLTAEVEDPTGYGRILRGGEAVVGIVEHKDADEAQRAVREINSGIYVFDAEALREGVSKLSNDNVQGEYYLTDVVTMAADGTVEVPGRGRVGAFRIDDVWQTEGVNDRVQLARMNAEVNRRIVTGWMRAGVTIIDPTSTWIQPDVDLANDVTLYPGVFLNGATTIGAGATVGPDVTVTDSEIREEATVTRSEVTLAVVGEGVRVGPFSNIRPGSVLDRDAKVGAFVETKNTHIGTEAAIPHMAYVGDSEVTAGSSIVAGSVLSRECAAPATVSDITSDSQDDTLNPEADQ", "output": "Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain."}]}
+{"id": "function_test_811", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDFYTPPTTAGPPTRGSPESVPTTAASTFPLRKRTRAHLRARDKSDGPAPSSRGTSDRLWSWVFLKQPLSLPEHNYQAHLGNNVFLIGGRFLSARQKPLNIAVLCVILILGGLYYGFVAPWTWNHISPAIPAVFTYIFLLCVASFLRASFSDPGILPRNIHLTDRIADGSIPNEYSVEPGIDAFDPRKNTTSLSCFKQPESSENLVYLKYCSTCKIWRPPRASHCSDCDNCVDFHDHHCIWLNNCVGRKNYRYFVAFVMTGGLCGLYIVGNSIAHVICYKRHMHMTIAESLRHRPMPLVMIFLGFLGAGYPLALVGFHLWIASRGESTHEFVSMNPVTKHVVDGHVGVTLSKCKVMGSHDGFKRFSDAVLAVVCARLCAHVSPHSNPVTKQTTPQGVQKSTFRHWKRF", "output": "The ERF2-ERF4 complex is a palmitoyltransferase specific for Ras proteins."}]}
+{"id": "function_test_812", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MWPFSSKKGVSGFSGSSTAEQVTHGIDATGLTAIVTGASSGIGAETTRVLALRGAHVIMGVRNMVAAKDVKDTILKDIPSAKVDAIELDLSSLDSVKKFASEFNSSGRPLNILINNAGIMACPFKLSKDNIELQFATNHIGHFLLTNLLLDTMKKTTRESKKEGRIVNVASEAHRFAYPEGIRFDKINDQSSYNNWRAYGQSKLANVLHANQLTKHLKEDGVNITANSLHPGTIVTNLFRHNSAVNGLINVIGKLVLKNVQQGAATTCYVALHPQVKGVSGEYFSDSNVYKTTPHGKDVDLAKKLWDFSINLVKQK", "output": "Involved in protein precursor import into chloroplasts. Part of the redox regulon consisting of TIC32, TIC 55 and TIC62. Has a NADPH-dependent dehydrogenase activity, but only after preincubation with lipids."}]}
+{"id": "function_test_813", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MVADFDSGWYEGAGDELGQGARNGVLRERLGGNEKAQVVRSRRKAVAWNVLMVLGLILYVLYSACFAQARQWWRTNGMARGSQAGRFQLVQVHHHGVGAEHATHLVLDVDAEFRKEAAAEYSVFALHGEGQELWPEAGRRRAANPFEYAYALREERATVVRAQQQVPEFMEPYLDFALERPDLAEQIKMDWGYENMFVPNITDKETVISLALMSSNAYVRLPNTGNWRNVTSWNSSVEGDQIHLGWDENGLRAHVFANEDRSVVVLALKGTSSQVLPGSGDDDETSANDKLNDNLLFSCCCARVSYLWTTVCDCYIKSYTCEESCLESELRRKDRYYQAGLDMYKQVLAEFPDASIWLTGHSLGGALASLVARTYGVPAVTFEAPGELLATQRLHLPQPPGLPNQLDTVWHFGHTADPIFMGTCNGASSACSIAGYAMETSCHSGKSCVYDVVNDRGWRVNLLHHRIHTVIDKILDDYDAVAACVPPDICHDCYNWNYVRWRDGTTSPMPSSVASKPTPTPTSPGSPSSTCKGRNWFGYCTEYA", "output": "Lipase which is essential for lysis of subvacuolar cytoplasm to vacuole targeted bodies and intravacuolar autophagic bodies. Involved in the lysis of intravacuolar multivesicular body (MVB) vesicles. The intravacuolar membrane disintegration by ATG15 is critical to life span extension (By similarity)."}]}
+{"id": "function_test_814", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTLFPIFADLTGRRVLVVGGGAVAVRKTQALLQAGAEVVVGAPRLDPALAALAEQGGIARLDGGFEPAWLAGAWLVVAATDDRAVNAAVSEAARARRVFCNVVDDAELSSFQVPSVVDRSPLIVAISSSGVAPVLARRLRERIESLFDHSLGQLAALAARYRPRIRAARPDLGQRRRFYDWLLDGPVAARLRQQQPGLAEQELEQALRAPQAAPRGSVVLVGAGPGDPGLLTLKALRALNEADIILYDRLVSEGVLALARRDAERVPVGKLPGEDHDATQARIHALMLAQARAGRRVVRLKGGDAFIFGRGGEELEYLRAHDVPYEVVPGITAALACAAYAGIPLTHRDHAQSVRMVTAHCRADQDTLDWAGLARDQQTLAFYMGVGQLDYVTARLLEHGRAPATPFALIENGSRPEQRVVTGTLAELPEIARRRSVRPPALLVIGEVAALADTLQWFGQHQHGLPGPQALAA", "output": "Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme."}]}
+{"id": "function_test_815", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTCVLLKAVVESDERADLRQFSRILQLGEKRYLLRNDILDAFADYCRDQERPVPPPSESRLSKLVFYTQEIIVDNESLCWIVRPRIAQQEVCRLLVEDLTIVPMTIPELLDLRDRLVNHYHPNEGDVFEIDVQPFYDYSPIIRDAKNIGKGVEFLNRYLSSKLFQDPRQWQQNLFNFLRIHRYNGYQLLINERIRSPQHLSEQVKQALVVLSDRPPTEAYSEFRFELQNLGFEPGWGNTVARVRDTLEILDQLLDSPDHQVLEAFVSRIPMLFRIALISPHGWFGQEGVLGRPDTGGQVVYILDQVKSLEKQMREDLELAGLGVLEAQPKIIVLTRLIPNAEGTLCNQRLEKIYGTNDAWILRVPFREFNPKVTQNWISRFEIWPYLETFAIDAERELRAEFGHVPDLIIGNYSDGNLVAFLLARRLKVTQCNIAHALEKSKYLFSNLYWQDLEDKYHFSLQFTADLIAMNAANFIISSTYQEIVGTPDSIGQYESYQSFTMPDLYHVVNGIELFSPKFNVVPPGVNEQVYFPYYHYTERLEGDRQRLEELLFTLEDPQQIYGYLEAPEKRPLFSMARLDRIKNLTGLAEAFGRSKALQERCNLILVAGKLRTADSSDREEIAEIEKLYQIIHQYNLHGKIRWLGIRLPKADSGEIYRIIADRQGIFVQPALFEAFGLTILEAMISGLPTFGTRFGGPLEIIQDGVNGFYINPTHLEEMAETIVRFLEACDRDPQEWQRISKAGIERVYSTYTWKIHCTRLLSLAKIYGFWNFSSQENREDMMRYMEALFHLLYKPRAQALLAEHLQR", "output": "Catalyzes the reversible conversion of sucrose and a nucleotide disphosphate (NDP) into fructose and NDP-glucose; although the reaction is freely reversible in vitro, the physiological reaction seems to be sucrose cleavage. Unlike characterized plant enzymes prefers ADP as a cosubstrate, whereas plants prefer UDP . Its preference for ADP over UDP suggests it may directly link sucrose and glycogen metabolism (Probable)."}]}
+{"id": "function_test_816", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGKTIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF", "output": "Protein that helps load RecA onto ssDNA during transformation . Required for DNA transformation . Not required for DNA uptake but for a later stage of transformation . Thought to interact at the cell pole with newly imported transforming ssDNA which it binds cooperatively, protecting linear and circular ssDNA from nuclease action . Forms bridges between DNA segments . Favors the loading of RecA onto ssDNA and formation of RecA-DNA filaments, triggering RecA-catalysis of ATP-driven homologous DNA pairing ."}]}
+{"id": "function_test_817", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNLNSIPAFQDNYIWVLTNDEGRCVIVDPGEAAPVLKAIAEHKWMPEAIFLTHHHHDHVGGVKELLQHFPQMTVYGPAETQDKGATHLVGDGDTIRVLGEKFTLFATPGHTLGHVCYFSRPYLFCGDTLFSGGCGRLFEGTPSQMYQSLMKINSLPDDTLICCAHEYTLANIKFALSILPHDSFINEYYRKVKELRVKKQMTLPVILKNERKINLFLRTEDIDLINEINKETILQQPEARFAWLRSKKDTF", "output": "Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid."}]}
+{"id": "function_test_818", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAGIVHGILFCGLFGLCWAVTGSRIYPASEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMESSQNNWLRTDWIPRSGAQRVYVEIKFTLRDCNSLPGVMGTCKETFNLYYYESNNDKERFIRETQYVKIDTIAADESFTQVDIGDRIMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGSDTSSLVEVRGSCVDNSEEKDVPKMYCGADGEWLVPIGNCLCNAGFEEHNGGCQACKVGYYKALSTDAACSKCPPHSYALREGSTSCTCDRGYFRADTDPASMPCTRPPSAPQNLISNVNETSVNLEWSPPQNSGGRPDVSYNLVCKRCGSDLTRCRPCGSGVHYSPQQNGLKTTKVSITDLQAHTNYTFEVWSINGVSKQNPGQDQAVSVTVTTNQAAPSTVTQIQPKDITRHSVSLTWPEPERPNGVILEYEVKYYEKDQNERTYRIVKTTSRSADIKGLNPLTAYVFHVRARTAAGYGEFSGPFEFTTNTVPSPMIGEGASPTVLLVSVAGSIVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVKTYVDPFTYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREIYVAIKTLKAGYTDKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTVIQLVGILRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYTTRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVSMLDKLIRNPNSLKRTGLDNSSRTNTTLLDPSSPEWSQVASVLDWLQAIKMERYKDNFTAAGYTSLEAVVHVNQDDLTRIGISSPSHQNKILSSVQGMRTQMQQIQGRMVPV", "output": "Receptor tyrosine kinase which binds membrane-bound ephrin family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Highly promiscuous, it has the unique property among Eph receptors to bind and to be physiologically activated by both GPI-anchored ephrin-A and transmembrane ephrin-B ligands including EFNA1 and EFNB3. Upon activation by ephrin ligands, modulates cell morphology and integrin-dependent cell adhesion through regulation of the Rac, Rap and Rho GTPases activity. Plays an important role in the development of the nervous system controlling different steps of axonal guidance including the establishment of the corticospinal projections (By similarity)."}]}
+{"id": "function_test_819", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKFAEHLSAHITPEWRKQYTQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELAKINTFYSEKLAEAQRRFATLQNELQSSLDVQKESSGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKILETSRGADWRVIHVEVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLFCGIFIGLNITLGFAAVFKLETDRTVWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHVLIFELNPRNNLSHQHLFEIAGFLGILWCLSLLACFFAPISIIPIYVYPLALYGFMVFFLINPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQLNSLSVILMDLEYMICFYSFELKWDESKGLLPNDPQEPEFCHKYSYGVRAIVQCIPAWLRFIQCLRRYRDTRRAFPHLVNAGKYSTTFFTVTFAALYSTHKEQNHSDTVVFFYLWVFFCIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYPQKAYYYCAIIEDVILRFAWTIQISITATTFKPHVGDIIATVFAPLEVFRRFVWNFFRLENEHLDNCGEFRAVRDISVAPLNADDQTLLEQMMDQEDGVRNRQKNRSWKYNQSISLRRPRLASQSKARDTKVLIEDTDDEANT", "output": "Plays a role in phosphate homeostasis. Mediates phosphate export from the cell. Binds inositol hexakisphosphate (Ins6P) and similar inositol polyphosphates, such as 5-diphospho-inositol pentakisphosphate (5-InsP7); these are important intracellular signaling molecules (By similarity). Potential receptor for xenotropic and polytropic murine leukemia retroviruses."}]}
+{"id": "function_test_820", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGVTQPAAPAYLRFPHPHGELVAFTAEDDVWLAPLDGGRAWRVSADNVPVNHPRISPDGTKVAWTSTRDGAPEVHVAPVEGGPAKRLTHWGSIRTQVRGWTADGRVLALSTYGQASLRRSWARALPLDGGPATTLPYGPVGDVAQGPHTVLLSAPMGREAAWWKRYRGGTAGKLWIDREDDGEFVRLHDGLDGNIEYPFWVGDRIAFLSDHEGTGALYSSLADGSDLRRHTPVDGFYARHAATDGSRVVYASAGELWTLDDLDGAEPRRLDIRLGGARVDLQSYPVNAARWFGSASPDHTARGSAVAVRGGVHWVTHRSGPARALAATPGVRNRLPRTFRVDGEEWVVWVTDAEGDDALEFAPATGLAPGATARRLAAGQLGRVLHLAVAPDGSRVAVASHDGRVLLVERESGEVREVDRSEDGDASGLVFSPDSSWLAWSHPGPEPLRQLKLANTTDLSVSEATPLRFKDYSPAFTLDGKHLAFLSTRSFDPVYDEHVFDLAFVEGARPYLITLAATTPSPFGPQRHGRPFETPDREETPDSEGTPTTRIDIEGLADRIVPFPVEAARYSRLRAAKDGVLWLRHPLTGVLGASRANPEDPDPNTELERYDLAQQRVEHLGGDADHFEVSGDGKRVLLWTDGRLKVVPSDRRASGDEDSDTNITVDLGRVRQTVEPAAEWRQMFDETGRIMRDHYWRADMNGVDWDGVLDRYRPVLDRVATHDDLVDLLWEVHGELGTSHAYVTPRGGHGSGARQGLLGADLSRHEDGAWRIDRVLPSETSDPDARSPLAAPGVAVRAGDAIVAVAGQAVDPVTGPGPLLVGTAGKPVELTVSPSGGGEVRHAVVVPLADEEPLRYHAWVADRRAYVHEKSGGRLGYLHVPDMQAPGWAQIHRDLRVEVAREGLVVDVRENRGGHTSQLVVEKLARRIVGWDLPRGMRPTSYPQDAPRGPVVAVANEFSGSDGDIVNAAIKALGIGPVVGVRTWGGVIGIDSRYRLVDGTLITQPKYAFWLEGYGWGVENHGVDPDVEVPQRPQDHAAGRDPQLDEAIALALAALEETPAKTPPSLP", "output": "Degrades oligopeptides in a sequential manner."}]}
+{"id": "function_test_821", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQADLYPSRQEDQPSWQERLDPVVYRSDLENAPIAAELVERFERDGYLVIPNLFSADEVALFRAELERMRQDPAVAGSGKTIKEPDSGAIRSVFAIHKDNELFARVAADERTAGIARFILGGDLYVHQSRMNFKPGFTGKEFYWHSDFETWHIEDGMPRMRCLSCSILLTDNEPHNGPLMLMPGSHKHYVRCVGATPENHYEKSLRKQEIGIPDQNSLSELASRFGIDCATGPAGSVVFFDCNTMHGSNGNITPSARSNLFYVYNHVDNAVQAPFCEQKPRPAFVAERENFKPLDIRPQQYL", "output": "Involved in the biosynthesis of 5-hydroxyectoine, called compatible solute, which helps organisms to survive extreme osmotic stress by acting as a highly soluble organic osmolyte. Catalyzes the 2-oxoglutarate-dependent selective hydroxylation of L-ectoine to yield (4S,5S)-5-hydroxyectoine."}]}
+{"id": "function_test_822", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSALTIYSETETREPLWHSTDAAEIADKLNARGVRFERWEADRDLGQDPAAETVINAYQHAIDKLVAEKGYQSWDVISLRADNPQKEALRAKFLNEHTHGEDEVRFFVEGAGLFCLHIDDQVYQVLCEKNDLISVPAGTPHWFDMGSEPNFTAIRIFDNPEGWIAQFTGDAIADAYPRLP", "output": "Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway."}]}
+{"id": "function_test_823", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNLNLILKSLEYSFIKENKKEIEKIEYDSRKVKEGDLFVCIEGYATDGHKYAKKAYDNGAKVIVCEKDLEDLSYYKDCTIIKVSDSRKALAIMSSNYYGNPSKHIKIIGITGTNGKTTSTFMMKAILEKAGYKVGLLGTIANYIGNKKIESHRTTPESLELQKLFKDMVDEKVDYCVMEVSSHSLYLDRVYGVEFKEAIFTNLTQDHLDFHKTFENYFNSKLILFKNAQNSVINIDDSYGEKVLKKALGNKITYGVEKNCDLKAENLHMHSRGVEFDTIFKNEKETIALNIPGKYNIYNALGSIGACLLEGIPLKTIKEALEDMPSVPGRCEIVTKNYNLGYDVIVDYAHTPDGLENILNTAREFTKGRLISVYGCGGDRDRTKRPIMGKVGSNLSDIAIITSDNPRTEDPKLIIKDVLEGIERDNYIVVEGRRDAIRKAMEIAKENDVIVVAGKGHEDYQILKDKTIHFDEREVIEELIKEI", "output": "Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan."}]}
+{"id": "function_test_824", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTVILERRESTSLWGRFCNWITSTENRLYIGWFGVLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAIIPTSAAIGLHFYPIWEAASVDEWLYNGGPYELIVLHFLLGVACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANAGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVVGIWFTALGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAVEAPSING", "output": "Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors."}]}
+{"id": "function_test_825", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTAILERRETTSLWARFCEWVTSTENRLYIGWFGCLMIPTLLTATSVFIIAFIAAPPVDIDGIREPVSGSLLYGNNIISGAVVPTSNAIGLHFYPIWEAASLDEWLYNGGPYQLIVCHFFLGICAYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFIIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENQSANAGYRFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAAWPVIGIWFTALGISTMAFNLNGFNFNQSVLDSQGRVLNTWADIINRANLGMEVMHERNAHNFPLDLA", "output": "Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors."}]}
+{"id": "function_test_826", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIHAGNAITVQMLADGIAEFRFDLQGESVNKFNRATIEDFKAAIAAVKANNDIKGLVVTSGKSTFIVGADITEFGQNFAQGEKAIVDWLMPVHEIFNSFEDLDLPKVAAINGMALGGGFEMCLVCDYRVMSEAAQVGLPEIKLGIYPGFGGSVRLSRLIGIDNAVEWMAMATPKKPAAALKDGAVDAVVAADKLLDAATDLVKQAISGRLNWKAKRQEKLEAVKLNPLEQMMAFNTAKGAVLAKANPAQYPAPKLLLDSLQAGASLARDEALKAEAEGFAKAAVTPQAEALIGLFINDQVVKKASKQHEKGAHPVNQAAVLGAGIMGGGIAYQAASKGTPIIMKDIGNPQLALGMKEANNLLTKQVERKKMKPAQMGETLARIRPTLSYEEFKEVDIVIEAVTENPKVKEIVLAETEKNVRENTIIASNTSTISITRLAKALQRPENFVGMHFFNPVHMMPLVEVIRGEKTSEEAIATTVVLAQKMGKTPIVVNDCPGFLVNRVLFPYFGAFDLLVKDGADFQQIDNVMSKFGWPMGPAYLIDVVGIDTGVHGAEVMAEGFPDRMKPDYKGAIEAMYEAKRLGQKNDVGFYKYELDKKGKKAKTVDPTAYEVIAPFVTGEKREFDNQEIIDRMMLALCNETVRCLEDNIVATASEADMAMIMGIGFPPFRGGPCRYIDQTGVAEYVALCDKYAHLGKAYEAPQMLRDMAANNKKFYG", "output": "Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate."}]}
+{"id": "function_test_827", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "AVGDDTPQLY", "output": "Lignin degradation and detoxification of lignin-derived products. Has activity towards ABTS and, to a much lesser extent, towards N,N-dimethyl-1,4-phenylenediamine, catechol and 2-methylcatechol."}]}
+{"id": "function_test_828", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKLLMLIVALMIIGVQSKDGYPMDHKGCKISCVINNKYCETECVTVLKGKKGYCYFWKLACYCEGLPNWAKVWDRATNKCRA", "output": "Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. This toxin compete with high affinity with 125I-Css4 bound on rat brain synaptosome and may bind with high affinity to Nav1.1/SCN1A, Nav1.2/SCN2A and Nav1.6/SCN8A."}]}
+{"id": "function_test_829", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGSLSAVPATNGNHAALNGSASTNGQHVNGSTHVNGNHSLNGSAQVNGHSATTANLEPIAVVGMSCRLPGDATDTQKLWELITKGRSAWSKVPTDRWNQEAFHDPAAEGKPGRTSTDGGHFLKDDIKAFDASFFGVNPIEATAMDPQQRLVLEIAYEAFENAGLTLQQLSGSNTGVYVGLWASDYQEMLLRDIDFPPIYQASGVGAAIASNRVSYCFNLHGPSLTLDTGCSASLVALHQAVHSLRAGETDKCFVAGVNLQLDPQRYGYQNKLSMFSKQGKSFTFDHRAKGASGYGRGEGCSGVVLMPLSKAQKQGFPIRAVIRNSVANQDGKTNGITVPSAAAQSAAIEKAYAQVGLTPYADYVEAHGTGTTVGDPIEAKAIAKVLGAGRQSDSPLPIGSLKANIGHTESAAGLTGLVKAVLMLENNMIPPQVNYEKPNPEIDLDALNLRIPISLENKPLKRISVNSFGYGGTNAHVVVDAADAIPIKPTNTDSQETKDTLRVREQLFVLSAASEKSSQDLVLNVAKYLESKADAADTDALLSRLAYTLSRRTVMENRIGVVASDLADLVEQLTKLSSEGIPRADRQTSPRIGFVFSGQGAQYPRMGQSLLGTWPTFTSSMKRAAECVKACGSSWDLLEELLKDASESRMEDPCIAQPMSTAVQISLVDALKDLGVIPTAVVGHSSGEIAAAYCAEAISFEDAMTVSYHRGRLTSELRLENKGKAGSMIAVGASAATVKQSIDQLGTAAANRITIACHNSPASVTVSGDADVIESLKQRLDEQDIWNRLLRTGGAAYHSPQMLQIAQKYHEAIKDVSGSVPASNVAMASSVTGEDQGDKPITRDYWVHNLVSPVRFTDALKKTCVGENGTRKVDLLLELGSHFQLESPIKQTLRTFTGEAAKVHYTGSLKRGEDAQLSMLQMLRSLYLQKSPVAFWKVNAGFGATFQLLTDLPPYPFDHSKTYWHEGRVSRAYKHRQNLPHELLGTLVHDNNPQEPRWRCLLNLKDVPWLSGHIIQGQTIFPATAYLSMVFQAARQDMAARNPQASINRFILRNVTFSQALVMENNKTDLEISLSLRPQAISARKSSQQWQEFRIFSTSADDVWIEHVRGLVQVILKSEAVQEDSFVPTRITLPPHAQHIPANQFYHRARDIGVNWSAPFDNLNDIKIAAGSCIADSSFVAGPSAGACEKDYVIHPGVMDAILYHGMMGVLIFDENDKSPVVPTFIEKMIVAEQDQAKPIEEVTCHAARTESALTFDIGIFEKNHEDNMVLQAWGVVATKLPDVSIGEGRKRDLCHVPDWATYLPKTTQEYIDGLCKKSLDDRSIIPEIKALEAMTVHYVKQALASTPEDEVAEGYQRNWYNWMKTLADQEPDPEYLKAGEEDDSVSAQVARRLGPRLGDILRGTTHSLSILNEDSMLSGLYLEGGNVRCISQIATYMGELGRLNPNMKIVEVGAGTGSATLPVLQALQAPNRVLASQYDFTDISPGFFPAARELLADYEGVVQYKILNAEKTAEENGFEPNSYDVLIASNVLHATPCIDAVLENVKTMLRPGGKLILMEPTENLPHYGLVFGSLAGWWAGVDEGRTLSPMLSRSQWIETLSKNGFINNGPIFEDYPVAEGGSIHVFVSEVPVPASTEAPLDVDIVSYSGEATYTDFAERLQKNLWDRSVQSCNVSSSMSGDKLSVIMPDFVDRVAWDMDGPLFESLRSRVAGSKVIIFVMCTAKSKEKRPSGDWIYGFVRSIRYEYASVRLVTLELESGLEAGVDALKTILNSPTADLSLPLEDIELEYMEREGQIFVSRVRSEPKFDNYVSRDLGRAGSEEALFLNERPMSAELGVPGVLDTIRWVDNPEITGPVDPDCVRLQLCAASINFKDVLVASGQLEGITQMRNDCSGIVLDVGANMTDKFKVGDRVCSLYSQSFTNYPMVHGLCCHVIPDDMDFADAASIPLVWSTVYYCLITIARLQKGESILIHSAAGAVGQASIMLAHHIGAEVFVTCGNDAKVELLNTEFGIPRDHIFSSRTTVFRDKIRAMTNGNGVDVVLNSLGGEMFRESCNTLAAHGRFVEIGRKDLMENALMPMEFLLNNITFSYVDFAHILATRTALASQLLGDVMKLFASGAVQHVRQIKYPISEMASAFRLVQAGKHTGKVILTVEPDVKVQVVPSKPSPVQLKPDATYLVVGGLGGLGKRLVDWTAEKGARNIVIFSRTAQPDADAQSFLDKLVSMGVTVRVEKCDVSSEESVIEALARIQETMPPIRGLFQAAMVLHDILLEHMTVEEWCKVTAPKVQGTWNLHKYLPEDMDFFVMLSSVVSMVGTVGAGNYASACAFQDGIARYRRRLGLTAYAVNIGAIVEAGYVSENPEVAVNLRKNGLGSVAISEFLSHLGDVIQNKTEYSQSSLGILPNGNERGLGEARWANDKRLAQIFGAETQAGNKTVGGGADNVGFALQSATTFQEAQDIICDAIVKQLATILAIQSDDIIPARSLDSYGLDSLVGVEL", "output": "Highly reducing polyketide synthase; part of the gene cluster that mediates the biosynthesis of the lipopeptide fusaristatin A . Fusaristatin A consists of a polyketide chain linked to three amino acid residues glutamine (Gln), dehydroalanine (dehydro-Ala), and beta-aminoisobutyric acid . The biosynthesis starts with formation of a linear polyketide chain by the highly reducing polyketide synthase PKS6 . The gene cluster does not contain an acyl-CoA ligase or an acyl-transferase, and it is therefore predicted that the polyketide is transferred directly to the nonribosomal peptide synthetase NRPS7 (Probable). Modules 1-3 from NRPS7 incorporate dehydro-Ala, Gln, and beta-aminoisobutyric acid in the compound, which is released by cyclization . The beta-aminoisobutyric acid units are most likely not freely available to the NRPS, but can be synthesized from thymine, which requires a dehydrogenase, a monooxygenase, and an aminotransferase. The fusaristatin A cluster contains a cytochrome P450 monooxygenase (FGSG_08207) and an aminotransferase (FGSG_17085), which theoretically can perform two of the enzymatic steps (Probable). The enzymes may however also be involved in biosynthesis of dehydroalanine or modification of the polyketide (Probable). The dehydro-Ala residue can be a result of cyclization, where serine is dehydrated (Probable). The last gene of the cluster encodes a protein with an A/B barrel domain found in variable enzymes, which hampers functional prediction (Probable)."}]}
+{"id": "function_test_830", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLMTATHREPIVLDTTVRDGSYAVNFQYTDDDVRRIVGDLDAAGIPYIEIGHGVTIGAAAAQGPAAHTDEEYFRAARSVVRNARLGAVIVPALARIETVDLAGDYLDFLRICVIATEFELVMPFVERAQSKGLEVSIQLVKSHLFEPDVLAAAGKRARDVGVRIVYVVDTTGTFLPEDARRYVEALRGASDVSVGFHGHNNLAMAVANTLEAFDAGADFLDGTLMGFGRGAGNCQIECLVAALQRRGHLAAVDLDRIFDAARSDMLGRSPQSYGIDPWEISFGFHGLDSLQVEHLRAAAQQAGLSVSHVIRQTAKSHAGQWLSPQDIDRVVVGMRA", "output": "Exhibits oxaloacetate decarboxylase activity. Lacks any detectable aldolase activity with 4-hydroxy-2-oxopentanoate (HOPA), 4-hydroxy-2-oxohexanoate (HOHA) or other 4-hydroxy-2-oxoacids."}]}
+{"id": "function_test_831", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTGLNETDARILVTSRHLFLWPLAETYFKNAEKVLQDCGVCDSFGRLLSTGLQCLYSVLMDTKMEPRVELLTRKRICEVLLSHTVEYADVEAILNRALIIAEQHNLTEYKFSLQLLLSRVFCRTSPKAAKVLLTRCVREAEEYAKVAEIYHSNNQSNPHRWVYEFLLATLEFQNVSQVANSIHNYANHHKHQHLQLLAMILNQSLPMDEISTDSDQISILCLVTQIAQCLRKGEILLAREILPKIHSKLESETFVWPSSYIDFFIDDTSKISIKWMSINQLYLLIYLISGFCYISDSTSGRASRFLQEGLRITGDFKHQERCVLEYLESQKWINNITKDMKYYLIATYLSRSRLSKAERILQSTEDDQTGFLGILKGMYLQKRGDLKKAEVHYRETAKNFSFRTDTFIISTLNLINILEDSAAASRCLESIEPLCNKHEKKIFKLWLLVLKVIREGPQVHQSNVLPRVIQQSSEYANTQLQYISLTELSERFGKLEHAEKMAISALELAKKSKDELWCLISGRILEDFYRSVQKYDKMRQQALENSAYSKLIEDIYSFV", "output": "Involved in sister chromatid cohesion. Forms a complex with mis4, which is required for the association of the cohesin complex with chromosomes."}]}
+{"id": "function_test_832", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSALTKASGALKSVDYEVFGRVQGVCFRMYTEEEARKLGVVGWVKNTRQGTVTGQVQGPEDKVNAMKSWLSKVGSPSSRIDRTNFSNEKEISKLDFSGFSTRY", "output": "Its physiological role is not yet clear."}]}
+{"id": "function_test_833", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "VLSGEDKNNIKTAWGKIGGHAAEYGAEALERMFVVYPTTKTYFPHFDVSHGSGQVKAHGKKVADALTTAVGHLDDLPGALSALSDLHAHKLRVDPVNFKLLSHCLLVTLANHIPADFTPAVHASLDKFLASVSTVLTSKYR", "output": "Involved in oxygen transport from the lung to the various peripheral tissues.; "}]}
+{"id": "function_test_834", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPEPAKSAPAPKKGSKKAVTKTQKKGDKKRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXMNSFVNDIFERIAGEASRLAHYNKRSTITSR", "output": "Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling."}]}
+{"id": "function_test_835", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTIRNQRFSLLKQPIYSTLNQHLIDYPLPSILSYWWGFGSLAGICLVIQIVTGVFLAMNYTPHVDLAFNSVEHIMRDVEGGWLLRYMHANGASMFFIVVYLHIFRGLYYASYSSPREFVWCLGVVIFLLMIVTAFIGYVLPWGQMSFWGATVITSLASAIPVVGDTIVTWLWGGFSVDNATLNRFFSLHYLLPFILVGASLLHLAALHQYGSNNPLGVHSEMDKIAFYPYFYVKDLVGWVAFAIFFSIWIFFAPNVLGHPDNYIPANPMSTPPHIVPEWYFLPIYAILRSIPDKAGGVAAIALVFISLLALPFFKEMYVRSSSFRPIYQGIFWLLLADCLLLGWIGCQPVEAPFVTIGQISSFFFFLFFAITPILGRVGRGIPKYYTDETHRTGSFS", "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."}]}
+{"id": "function_test_836", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "PLRDTHPHLTMKNQTFHLQGFVDGLRDLTTTERHHNAYGDPFTTLSPVVPTVSTTLSPPSTTGDPALSPEMSPSSLLGLLAGLQVVYFLWTKIPTIAQNLDWWWTSLSFPGGIPECTGQNSQFQTCKHLPTSCPPTCNGFRWMYLRRFIIYLLVLLLCLIFLLVLLDWKGLLPVCPLQPTTETTVNCRQCTLSVQDTYTPPYCCCLKPTAGNCTCWPIPSSWALGNYLWEWALARFSWLNLLVPLLQWLGGISLIAWFLLIWMIWFWGPALLSILPPFIPIFVLFFLIWVYI", "output": "The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. The large envelope protein probably also assumes fusion between virion and host membranes. In its internal conformation the protein plays a role in virion morphogenesis and mediates the contact with the nucleocapsid like a matrix protein (By similarity).; "}]}
+{"id": "function_test_837", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "GVLILSGDHLYRMDYMDFVQSHRQRDAGISICCLPIDGSRASDFGLMKIDDTGRVISFSEKPRGADLKEMEEAEKKPYIASMGVYIFKKEILLNLLRWRFPTANDFGSEIIPAAAREINVKAYLFNDYWEDIGTIKSFFEANLALAEQPSKFSFYDASKPMYTSRRNLPPSMISGSKITDSIISHGCFLDKCRVEHSVVGIRSRIGSNVHLKDTVMLGADFYETDMERGDQLAEGKVPIGIGENTSIQNCIIDKNARIGKNVTIANAEGVQEADRASEGFHIRSGITVVLKNSVIADGLVI", "output": "This protein plays a role in synthesis of starch. It catalyzes the synthesis of the activated glycosyl donor, ADP-glucose from Glc-1-P and ATP."}]}
+{"id": "function_test_838", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTDFLRDDIRFLGQILGEVIAEQEGQEVYELVEQARLTSFDIAKGNAEMDSLVQVFDGITPAKATPIARAFSHFALLANLAEDLYDEELREQALDAGDTPPDSTLDATWLKLNEGNVGAEAVADVLRNAEVAPVLTAHPTETRRRTVFDAQKWITTHMRERHALQSAEPTARTQSKLDEIEKNIRRRITILWQTALIRVARPRIEDEIEVGLRYYKLSLLEEIPRINRDVAVELRERFGEGVPLKPVVKPGSWIGGDHDGNPYVTAETVEYSTHRAAETVLKYYARQLHSLEHELSLSDRMNKVTPQLLALADAGHNDVPSRVDEPYRRAVHGVRGRILATTAELIGEDAVEGVWFKVFTPYASPEEFLNDALTIDHSLRESKDVLIADDRLSVLISAIESFGFNLYALDLRQNSESYEDVLTELFERAQVTANYRELSEAEKLEVLLKELRSPRPLIPHGSDEYSEVTDRELGIFRTASEAVKKFGPRMVPHCIISMASSVTDVLEPMVLLKEFGLIAANGDNPRGTVDVIPLFETIEDLQAGAGILDELWKIDLYRNYLLQRDNVQEVMLGYSDSNKDGGYFSANWALYDAELQLVELCRSAGVKLRLFHGRGGTVGRGGGPSYDAILAQPRGAVQGSVRITEQGEIISAKYGNPETARRNLEALVSATLEASLLDVSELTDHQRAYDIMSEISELSLKKYASLVHEDQGFIDYFTQSTPLQEIGSLNIGSRPSSRKQTSSVEDLRAIPWVLSWSQSRVMLPGWFGVGTALEQWIGEGEQATQRIAELQTLNESWPFFTSVLDNMAQVMSKAELRLAKLYADLIPDTEVAERVYSVIREEYFLTKKMFCVITGSDDLLDDNPLLARSVQRRYPYLLPLNVIQVEMMRRYRKGDQSEQVSRNIQLTMNGLSTALRNSG", "output": "Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle."}]}
+{"id": "function_test_839", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKLLITGGCGFLGSNLASFALSQGIDLIVFDNLSRKGATDNLHWLSSLGNFEFVHGDIRNKNDVTRLITKYMPDSCFHLAGQVAMTTSIDNPCMDFEINVGGTLNLLEAVRQYNSNCNIIYSSTNKVYGDLEQYKYNETETRYTCVDKPNGYDESTQLDFHSPYGCSKGAADQYMLDYARIFGLNTVVFRHSSMYGGRQFATYDQGWVGWFCQKAVEIKNGINKPFTISGNGKQVRDVLHAEDMISLYFTALANVSKIRGNAFNIGGTIVNSLSLLELFKLLEDYCNIDMRFTNLPVRESDQRVFVADIKKITNAIDWSPKVSAKDGVQKMYDWTSSI", "output": "Catalyzes the isomeration of CDP-paratose to CDP-tyvelose."}]}
+{"id": "function_test_840", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLSVVILFLLVAENSSQSYTGNPVICMGHHSVANGTMVKTLTDDQVEVVTARELVESQTLPELCPSPLRLVDGQTCDIINGALGSPGCDHLNGAEWDVFIERPNAVDTCYPFDVPDYQSLRSILANNGKFEFIAEEFQWNTVIQNGKSSACKRANVNDFFNRLNWLVKSTGNAYPLQNLTKVNNGDYARLYIWGVHHPSTDTEQTNLYKNNPGRVTVSTKTSQTSVVPNIGSRPLVRGQSGRISFYWTIVEPGDLIVFNTIGNLIAPRGHYKLNNQKKSTILNTPIPIGSCVSKCHTDKGSVSTTNPFQNISRIAIGECPKYVKQGSLKLATGMRNVPEKASRGLFGAIAGFIENGWQGLIDGWYGFRHQNAEGTGTAADLKSTQAAIDKINGKLNRLIEKTNEKYHQIEKEFNKIEGRVQDLEKYVEDTKIDLWSYNAELLVALENQHTIDVTDSEMNKLFERVRRQLRENAEDQGNGCFEIFHKCDNNCIESIRNGTYDHDIYRDEAINNRFQIQGVKLIQGYKDIILWISFSISCFLLVALLLAFILWACQNGNIRCQICI", "output": "Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.; "}]}
+{"id": "function_test_841", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSPQTETKTGFGFKAGVKDYRLNYYTPEYETKDTDILAAFRMTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRVPPAYSKTFQGPPHGIQAERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFVAEALFKSQAETGEVKGHYLNATAGTCEEMMKRAIFARELGAPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQRNHGMHFRVLAKALRMSGGDHVHAGTVVGKLEGEREVTLGFVDSLRDDYIEKDRSRGIYFTQDWVSMPGVFPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVASEACVQARNEGRDLAREGNEIIREASKWSPELAAACEVWKEIKFEFETIDTL", "output": "RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site."}]}
+{"id": "function_test_842", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "VGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIESVAGEENQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPPAYTKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRLSGGDHIHAGTVVGKLEGEREITLGFVVLLRDDFVEKDRSRGIYFTQDWVSIPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVRARNEGRDLAREGNEIIREASKWSLELAAACEVWKEIKFDFEAMDTL", "output": "RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site."}]}
+{"id": "function_test_843", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQRNNGEGRPEGMHRISRFLHGNPFKNNASPQDDSTTRTEVYEEGGVEDSAVDYDNASGNAAPRLTAAPNTHAQQANLQSGNTSITHETQSTSRGQEATTSPSLSASHEKPARPQTGEGSDNEDEDEDIDALIEDLYSQDQEEEQVEEEESPGPAGAAKVVPEELLETDPKYGLTESEVEERKKKYGLNQMKEEKTNNIKKFLSFFVGPIQFVMELAAALAAGLRDWVDFGVICALLLLNATVGFVQEYQAGSIVDELKKTMALKASVLRDGRVKEIEASEIVPGDILHLDEGTICPADGRLITKDCFLQVDQSAITGESLAVDKHQNDTMYSSSTVKRGEAFMVVTATADSTFVGRAASLVGAAGQSQGHFTEVLNGIGTILLVLVILTLLCIYTAAFYRSVRLAALLEYTLAITIIGVPVGLPAVVTTTMAVGAAYLAKKKAIVQKLSAIESLAGVEILCSDKTGTLTKNRLSLGEPYCVEGVSPDDLMLTACLASSRKKKGLDAIDKAFLKALRNYPKAKDQLSKYKVLDFHPFDPVSKKITAYVEAPDGQRITCVKGAPLWVFKTVQDDHEVPEAITDAYREQVNDMASRGFRSLGVARKADGKQWEILGIMPCSDPPRHDTARTIHEAIGLGLRIKMLTGDAVGIAKETARQLGMGTNVYNAERLGLSGGGDMPGSEVNDFVEAADGFAEVFPQHKYAVVDILQQRGYLVAMTGDGVNDAPSLKKADAGIAVEGASDAARSAADIVFLAPGLSAIIDALKTSRQIFHRMYAYVVYRIALSLHLEIFLGLWLIIRNQLLNLELIVFIAIFADVATLAIAYDNAPYAMKPVKWNLPRLWGLATIVGILLAIGTWIVNTTMIAQGQNRGIVQNFGVQDEVLFLQISLTENWLIFITRCSGPFWSSFPSWQLSGAVLVVDILATLFCIFGWFKGGHQTSIVAVIRIWMYSFGIFCLIAGVYYILSESSSFDRWMHGKHKERGTTRKLEDFVMQLQRTSTHHEAEGKVTS", "output": "The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses."}]}
+{"id": "function_test_844", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIIERARELAVRAPARVVFPDALDERVLKAAHYLQQYGLARPVLVASPFALRQFALSHRMAMDGIQVIDPHSNLSMRQRFAQRWLARAGEKTPPDAVEKLSDPLMFAAAMVSAGEADVCIAGNLSSTANVLRAGLRVIGLQPGCKTLSSIFLMLPQYAGPALGFADCSVVPQPTAAQLADIALASADTWRAITGEEPRVAMLSFSSNGSARHPNVANVQQATELVRERAPQLLVDGELQFDAAFVPEVAAQKAPDSPLQGRANVMIFPSLEAGNIGYKITQRLGGYRAVGPLIQGLAAPLHDLSRGCSVQEIIELALVAAVPRQADVSRERSLHTLVE", "output": "Required for the use of ethanolamide (EA) as carbon, but not nitrogen, source (Probable). Involved in acetate metabolism during growth on EA, when expressed independently of the eut operon it can restore growth to a double pta-acs deletion mutant . Required for acetate excretion during growth on EA .; "}]}
+{"id": "function_test_845", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MMSKMGAMFVLLLLFTLASSLQEGDVQARKTRLKSDFYRALARDDRGCTRTCGGPKCTGTCTCTNSSKCGCRYNVHPSGWGCGCACSG", "output": "Sigma-conotoxins bind and inhibit serotonin-gated ion channels. This peptide selectively and reversibly inhibits 5-hydroxytryptamine 3 receptor (HTR3A) through competitive antagonism (IC(50)=53-86.8 nM)."}]}
+{"id": "function_test_846", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEGLSLLQLPRDKFRKSSFFVWVIILFQKAFSMPLGVVTNSTLEVTEIDQLVCKDHLASTDQLKSVGLNLEGSGVSTDIPSATKRWGFRSGVPPQVVSYEAGEWAENCYNLEIKKPDGSECLPPPPDGVRGFPRCRYVHKAQGTGPCPGDYAFHKDGAFFLYDRLASTVIYRGVNFAEGVIAFLILAKPKETFLQSPPIREAANYTENTSSYYATSYLEYEIENFGAQHSTTLFKINNNTFVLLDRPHTPQFLFQLNDTIQLHQQLSNTTGKLIWTLDANINADIGEWAFWENKKISPNNYVEKSCLSKLYRSTRQKTMMRHRRELQREESPTGPPGSIRTWFQRIPLGWFHCTYQKGKQHCRLRIRQKVEE", "output": "[Small/secreted glycoprotein]: Seems to possess an anti-inflammatory activity as it can reverse the barrier-decreasing effects of TNF alpha. Might therefore contribute to the lack of inflammatory reaction seen during infection in spite the of extensive necrosis and massive virus production. Does not seem to be involved in activation of primary macrophages. Does not seem to interact specifically with neutrophils.; "}]}
+{"id": "function_test_847", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MINVMYKNSCPNCGGDISADRLLNGLPCETCLPYINGIDGIDHISKVKALYNILLDNDKIKNYWNLYYNITTFETVFKYFKDKTGYEPWSLQKLWLRRLVSNQSFTMSAPTGLGKTTTLMTYSVFIGQDVVYIVPTKSLMEQVCKRLEKLGAQVSCGKVDQRKVSVITISYLNKNADSITSYKPNFVAIDDADAVIKSGKTTDRLVSLLGIPNDVYESAIQLIRLRNKYYFSNEFTEEIKEKIRELELKIAEFKDKISQLVIASATIRPKGIKQKALRLLTGFEPSSIQLYARNIIDTYTDNLDLSIIKELGSGGLILVSKEYGRSRLNEIKKYVEDLGFNAKLAISGRKFLDDFSQGKVDILVGSASYYGVAVRGIDEPKRLKYVIYYGVPKIKAKLFDALSNPFTLLRVGKMIGVNFSELQNKILVLSPSEAQLLKFSIIKGETINYQKLEQLRQELLYYISLVKDKLKEIGEETLISDNFVIAKQNTNYYIIYPDMITYLQGSGRASRLYNGGLTLGFSIILVDDKHIFEILKKKMQKLFPNTNFTSLSNINLSEIKTKLEESRKEEGNRVHFNISTGLLIVESPTKAKTIAKMFSRPSVRVINKVPVYETIIVDGNQIYVLDVVASKGHIVDLTLEDIGYYGIKIEYSGIIKPYYDLIKKCLDCNKTFSIASDKCPYCGSTNVQTAQTTINLLRELALSVDKVFIASDPDTEGEKIAYDLASFLSPYNSNIYRITYHEITKKAILEALRNPMKINTNLVMSQIVRRIEDRWIGFTLSNLLKTKFNGHNHGAGRVQTPVLGWIVDKTIKYKSAMGYVVYIDIAGYPIKMHFSERKKMEEYINNLQVVKIEKIFEEKILLSPLPPFTTDTLLIEANMKYKLPANLVMKIAQDLFEAGLITYHRTDSTHISSVGIEIAKEYLQKQGLIKDFVPRSWESSEEGAHEAIRPTRAIDVNELIQEIEENPYKYSIRFSKLHFLIYDLIFRRFMASQMSHAVGTKSRYLIKLNKNDNINAELLSNAEGGFIKVYPVKVYNLPLGEVKPKVNTGKGSSEQLLSYSDVISLMKSKGIGRPSTYAKTIENLVRHGYIVSSKRKSYLIATNRGISAYQFLSSKFYDLVSEGTTAKLMSKLDDIALSKLSASTVLLEIFSEISTLVNPLKSEQNV", "output": "Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication."}]}
+{"id": "function_test_848", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPDPAKTAPKKKSKKAVT", "output": "Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.; "}]}
+{"id": "function_test_849", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "VGCEECPAHCKGKNAIPTCDDGVCNCNV", "output": "Calcium channel activator. Rapidly and reversibly activates ryanodine receptor 1 (RYR1)."}]}
+{"id": "function_test_850", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRYAFAAEATTCNAFWRNVDMTVTALYEVPLGVCTQDPDRWTTTPDDEAKTLCRACPRRWLCARDAVESAGAEGLWAGVVIPESGRARAFALGQLRSLAERNGYPVRDHRVSAQSA", "output": "Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA (By similarity). The apo-form has been shown to act as a protein disulfide reductase."}]}
+{"id": "function_test_851", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTVSRLRPYATTVFAEMSALATRIGAVNLGQGFPDEDGPPKMLQAAQDAIAGGVNQYPPGPGSAPLRRAIAAQRRRHFGVDYDPETEVLVTVGATEAIAAAVLGLVEPGSEVLLIEPFYDSYSPVVAMAGAHRVTVPLVPDGRGFALDADALRRAVTPRTRALIINSPHNPTGAVLSATELAAIAEIAVAANLVVITDEVYEHLVFDHARHLPLAGFDGMAERTITISSAAKMFNCTGWKIGWACGPAELIAGVRAAKQYLSYVGGAPFQPAVALALDTEDAWVAALRNSLRARRDRLAAGLTEIGFAVHDSYGTYFLCADPRPLGYDDSTEFCAALPEKVGVAAIPMSAFCDPAAGQASQQADVWNHLVRFTFCKRDDTLDEAIRRLSVLAERPAT", "output": "Involved in the lysine biosynthetic pathways. It catalyzes the transfer of an amino group from L-glutamate to N-succinyl-2-l-amino-6-oxoheptanedioate (N-succinyl-2-l-amino-6-ketopimelate) in a PLP-dependent reaction, yielding as products N-succinyl-l-2,6-diaminoheptanedioate (N-succinyl-diaminopimelate) and 2-oxoglutarate (Probable)."}]}
+{"id": "function_test_852", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQRLDALLPTLRERAQETEDLRRIPDDSMKALQETGFFRLLQPEQWGGYQADPVLFYSAVRKIASACGSTGWVSSIIGVHNWHLALFSQQAQEDVWGNDTDVRISSSYAPMGAGQVVDGGYTVNGAWAWSSGCDHASWAVLGGPVIKDGRPVDFVSFLIPREDYRIDDVWNVVGLRGTGSNTVVVEDVFVPTHRVLSFKAMSNLTAPGLERNTAPVYKMPWGTIHPTTISAPIVGMAYGAYDAHVEHQGKRVRAAFAGEKAKDDPFAKVRIAEASSDIDAAWRQLSGNVADEYALLVAGEEVPFELRLRARRDQVRATGRAISSIDKLFESSGATALANGTPLQRFWRDAHAGRVHAANDPERAYVMYGTGEFGLPITDTMV", "output": "Catalyzes the o-hydroxylation of 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione (3-HSA) to 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione (3,4-DHSA) in the catabolism of cholesterol."}]}
+{"id": "function_test_853", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSPQTETKASVGFKAGVKEYKLTYYTPEYQTKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYRIERVVGEKDQYIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPTAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALFKAQTETGEIKGHYLNATAGTCEEMMKRAVFARELGVPIVMHDYLTGGFTANTTLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDFIEQDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVKARNEGRDLAREGNEIIREASKWSPELAAACEVWKEIVFNFAAVDVLDK", "output": "RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site."}]}
+{"id": "function_test_854", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKVTLPEFERAGVMVVGDVMLDRYWYGPTSRISPEAPVPVVKVNTIEERPGGAANVAMNITSLGANARLVGLTGIDDAARALSKSLADVNVKCDFVSVPTHPTITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALSSIGALVLSDYAKGALASVQQMIQLARKAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVVGKCKTEEEIVERGMKLIADYELSALLVTRSEQGMSLLQPGKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAAGNSLEEACFFANAAAGVVVGKLGTSTVSPIELENAVRGRAETGFGVMTEEELKLAVAAARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGDSRPVNPLEQRMIVLGALEAVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSKEVWANGGEVLVLNFEDGCSTTNIIKKIQQDKKG", "output": "Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.; "}]}
+{"id": "function_test_855", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNIAAVFNALLVSVLATVLWKYIKLREHAFMVEEELVLMRQSQELSQVQIDYHAALQTLLEDGTRMVCTGRMHTDRICRFESLCYSTEAEEFIYFHSNSSVMLPNLGSRRFQPALLDLSSVEDHNTQYFNFVELPAAALKFMPKPVFVPDVALIANRFNPDNLMHVFHDDLLPIYYTMQQFTDLDPETRLFFMEGWSEGVHFDLYKLLSNKQPLLREQLKTLGRLLCFTKSYVGLSKITTWYQYGFVQPQGPKANILVSGNEIRQFTKFMMQKLNVSLEESSSEEYIVVFSRTINRLILNEAELILALAQEFQMKTITVSLEEHSFSDIVRLISNASMLVSMHGAQLVMSLFLPRGATVVELFPYAINPEHYTPYKTLATLPGMDLQYIAWQNTAREDTVTYPDRPWDQGGIAHLDKAEQERIIKSTEVPRHLCCRNPEWLFRAYQDTKVDIPSLIHVIRQTVKSKPGPKKKWSGSLYPGKVRDARCQASVQGTSEARLSVSWQVPWNLKYLKVREVKYEVWIQEQGENTYMPYILSHQNHTFSENIKPFTIYLVWIRCIFNKNLLGPFADVLLCST", "output": "O-linked mannose beta-1,4-N-acetylglucosaminyltransferase that transfers UDP-N-acetyl-D-glucosamine to the 4-position of the mannose to generate N-acetyl-D-glucosamine-beta-1,4-O-D-mannosylprotein. Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (By similarity)."}]}
+{"id": "function_test_856", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEVVILAAGQGKRMRSALPKVLQPIAGRPMLEHVIAAAQALEARRICVVHGHGGEAVRARLQHAAVQWALQQPQLGTGHAVLQALPHLTDGDMALVLYGDVPLIGVPTLRRLEAAAGGERLALLTVELADPSGYGRILRDGAGRVVRIVEEKDASADERRVREVNTGILVAPVARLRDWLARLGNDNAQREYYLTDIIGMAVAEGVEVTTVQPDAIWETLGVNSKAQLAELERLHQRNIATRLMEDGVTLFDPSRIDVRGELLCGRDVEIDVNCVFEGRVEIADDVRIGANCVIRNARIGAGTRLAPFSHVEDTTTGRDCVIGPYARTRPGTTLGDGVHLGNFVEVKNSAIADDSKANHLAYIGDADIGRRVNVGAGTITCNYDGANKYRTTIGDDVFIGSDTQLVAPVRVGRGATLGAGTTLTKDAPEDQLTVSRARQISIPGWKRPVKKKAGE", "output": "Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain."}]}
+{"id": "function_test_857", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPKIVLNGVTVDFPFQPYKCQQEYMTKVLECLQQKVNGILESHTGTGKTLCLLCTTLAWREHLRDGISARKIAERVQGELFPDRALSSWGNAAAAAAGDPIACYTDIPKIIYASRTHSQLTQVINELRNTSYRPKVCVLGSREQLCIHPEVKKQESNHIQIHLCRKKVASRSCHFYNNVEEKSLEQELASPILDIEDLVKSGSKHRVCPYYLSRNLKQQADIIFMPYNYLLDAKSRRAHNIDLKGTVVIFDEAHNVEKMCEESASFDLTPHDLASGLDIIDQVLEEQTKTAQQGEPHPEFSADSTSPGLNMELEDIAKLKMILLRLEGAIDAVELPGDDSGVTKPGSYIFELFAEAQITFQTKVCILDSLDQIIQHLAGRAGVFTNTAGLQKLADIIQIVFSVDPSEGGPGSLAGLGALQSYKVHIHPDAGHRQTAQRSDAWSTTAARKRGKVLSYWCFSPGLSMRELVRQGVRSLILTSGTLAPVSSFALEMQIPFPVCLENPHIIDKHQIWVGVVPRGPDGAQLSSAFDRRFSEECLSSLGKALGNTARVVPCGLLIFFPSYPVMEKSLEFWRARDLARKMEALKPLFVEPRSKGSFSETISAYYARVAAPGSTGATFLAVCRGKASEGLDFSDTNGRGVIVTGLPYPPRMDPRVVLKMQFLDEMKGQGGAGGQFLSGQEWYRQQASRAVNQAIGRVIRHRQDYGAVFLCDHRFAFADARAQLPSWVRPHVRVYDNFGHVIRDVAQFFRVAERTMPAPAPRATAPSVREGEDAVREVKSPGPLFSTRKAKSLDLHVPSLKQRSSGSAAAGDPESSLCVEYEQEPIPARQRPRGLLAALEHSEQQAGSPGEEQAHSCSTLFLLSAKRPAEEPRGGRKKIRLVSHPEEPVAGAQTDRAKLYMVAVKQELSQANFATFTQALQDYKGSDDFAALAACLGPLFAEDPKKHSLLQGFYQFVRPHHKQQFEEVCIQLTGRGCGYRPEHSIPRRQPAQPVLDPTGRTAPDPKLTLSKAAAQQLDPREHLNQGRPHLSPRPPPTGDPGSHPQWRSGVPRAGKQGQRAVSAYLADARRALGSAGCSQLLAALRAYKQDDDLDKVLAVLAALTTAKPEDFPLLHRFSMFVRPHHKQRFSQTCTDLTGRPYPGMERPGPQEESLVVPPVLTHGAPQPGPSRSEKPGKTQSKISSLLRQRPAGTVGAGSEDAGPSQSPGPPHGPAASEWGEPHGRDIAGQQAAGAPGGPLSAGCVCQGCGAEDVVPFQCPACDFQRCQACWQRHLQASRMCPACHTASRKQSVTQVFWPEPQ", "output": "ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere."}]}
+{"id": "function_test_858", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDLRGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLKRNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK", "output": "Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity)."}]}
+{"id": "function_test_859", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "EITTFAALTERFNLPNGNYQRPKLLYCSNGGHFLRILPDGKVDGTRDRSDPYIQLQFYAESVGEVYIKSLETGQYLAMDSDGRLYASQSPSEECLFLERLEENHYNTYKSKMHADKDWFVGIKKNGKTKLGSRTHFGQKAILFLPLPV", "output": "Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling."}]}
+{"id": "function_test_860", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNNPPPMMGYQPSGGGSVTQMLGTPQPLAQPLHQTGPTQQAQQMLQQPPGLVSSGTRQMLGQIGQVGSNPLCHPHQSDPTLVNNPIWKLQLQLAAISRQSVGQANVYARQNAMKKYLMTQTNGSQQPADMAKSLVDFTKQYLLEMAADPAVPNNAALAASGQQIQRPHGTPVSTPSTPKAELANNAQTTPSILLQQQQKKLSQFNIDEDDEVEHRMMAPVNTKYDEQLWHTIDLSNLSVYNLNENLFKYDFLTRLYLNGNNLTHLPASIKQLQNLRVLDVSHNRLTELPPELGMCYQLKYLYFFDNMVSTLPWEFGNLFNLQFLGCEGNPLDRQLIKILTEKSVTGLIFYLRDNAPEIPLPEPRRFIEVNADGESVETYRCIEESTNHLNEELLKKSFTLLSYNTLCQHYATPKMYRFVPSWALSWDYRREKLKDEVLAYQTDIICLQEVESKTYEEFWLPILEKQGYSGIFHAKTRARTMQSKDAKKVDGCCIFYKNSEFTAVFKDAIDFSSVWMKHKKFQRTEDYLNRAMNKDNVALIIKLRHERTGEHVWVVTTHLHWDPHFNDVKTFQVAVMLDYIEKLLKQHGGVGSPQDKKKIPLVICGDFNSQLDSAVVELFNTGSVRSHKDIEGRDFGYMSQKNFAHGLALKSSYGSIGELPFTNLSPTFTDVIDYIWYSTQALRVRGLLGEIDPAYAAKFIGLPNDKIPSDHIPLLARFEFTKGSSATINTNGNKTV", "output": "Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover (By similarity). Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA (By similarity)."}]}
+{"id": "function_test_861", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MMQPTPAPSSAPGSPQRTQAEPEMETPSYPQPPQNVGTAPFSVLVKLFEKLATERKQERRRKLLDAWFRHWRREKGFDLYPVLRLLLPQKDRDRAVYGLKEKNLAKTYIKLIPLGMRDPDAIRLLNWKKPTERDKSSGDFPQVLCEVVSKRSSVIEGTLTIDELNEILDDIAKNMGKSDVQSKILRRIYNNSTADEQRWIIRIILKDMNISVKETTVFAVFHPDAQDLYNTCSDLKKVAWELWDPSRRLNAKDKEIQIFHAFAPMLCKRPTRKIEETVKAMGGSKFIIEEKLDGERMQLHKRGNEYFYCSRKGKDYTYLYGKHIGAGSLTPFIDSAFDSRIDDIILDGEMLVWDPVSERNLPFGTLKTAALDRSKKENNPRPCFKVFDLLYLNGMSLLDKTVKFRKNNLRHCIKPIPGRIEFVEEYQGETANDIRKRMEQVMENRGEGLVIKHPKAKYILNGRNTDWIKVKPEYMDNMGETVDVLVVAGNYGSGKRGGGVSTLICAVMDDRRPDSDDEPKYSSFVRIGTGLSFADYVWVRSKPWKVWDPKNPPEFLQTAKKGQEDKGDVYLEPEDSFILKVKAAEITPSDQYHMGFTMRFPRALAIRDDLSIADCMTATEVFESLKSERKRKMEDDAGITTKKRKTTVKKVALLPEYSGPNLKKVAVKTDIFNGMKFVVFSDPKSRTGEADKKELMKTIHANGGTCSQIVNKNSEAIVIYGGSITPYDLKLVIDKGIHDVIKPSWITDSVTLGEPAPFKKKYFFHATEERKYADEYNEDDGEEEGAVPSADEQERDVKSGTVEPGSETEDEDEEQAPEIKEEQDGELHEWLKVDDRKSPALPAHDEEDSVTEDDSDNADVADEEEPDLDDWFQVKGETEDEGAGALATASRHRETTPDVDGDVKMGESEEAMDYDPDVIFKHLCFYLDSPANAQRHGMATRPKYEAAITKSFEEVEKLIKDNGGKIVDLDEPKLTHVVLDKRDDSRRVELMKRTSKPRRRHLVLSDYIEACIDEGTLLDEEEFAP", "output": "Involved in ds DNA break repair. Has a role in non-homologous integration (NHI) pathways where it is required in the final step of non-homologous end-joining."}]}
+{"id": "function_test_862", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEMNPLLVCATVAIVFATTTIIRILFSSSSLPQMKWPSGPRKLPIIGNLHQLGDDVLHVALAKLAKVHGSVMTIWIGSWRPVIVISDIEKAWEVLVNKSADYGARDMPEITKIASASWHTISTSDAGSFWQNVRKGLQSGAMGPLNVAAQNQYQERDMKRLIKAMSDEAANNNGIVKPLDHIKKNTVRLLTRLIFGQAFDDNKFIESMHYEIEDIIRISGYARLAEAFYYAKYLPSHKKAEREAFLVKCRVEELVRPLLSSKPPTNSYLYFLLSQNFEEEVIIFCIFELYLLGVDSTSSTTTWALAYLIREQGAQEKLYQDIRMTLGDVDLVKIEDVNKLKYLQGVVKETMRMKPIAPLAIPHKTAKETTLMGTKVAKGTRIMVNLYALHHNQNIWPDPYKFMPERFLEGETGTAYNKAMEQSFLPFSAGMRICAGMDLGKLQFAFALANLVNAFKWSCVEEGKLPDMGEELSFVLLMKTPLEARIAGRNV", "output": "Involved in the last but one step of the biosynthesis of berberine, an antimicrobial benzylisoquinoline alkaloid. Converts (S)-tetrahydrocolumbamine (THC) to (S)-tetrahydroberberine (THB) also called (S)-canadine."}]}
+{"id": "function_test_863", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSVTLDLSRVSSDAAPATPVTKPLINLSGLTRPQLVAALVESGVVEHGKAKMRATQIFRWMHHRGVTDFADMSDVAKETRARLAEAFTIARPEIVERQVSKDGTRKWLIRMAPGIEVESVYIPGVGRAGALCVSSQVGCTLNCSFCHTGTQPLVRNLTAAEIVAQVQVAKDDLAEWPSDKEDRQLSNIVFMGMGEPLYNLGQVADAIEIISDNEGIAISRRRITVSTSGVVPMLEKLGSTTQAMLAISLHATNDPLRDVLVPLNKKYPIAELMAGIRAYPGLSNARRVTFEYVMLKGVNDSPEEARALVKLIKGIPAKINLIPFNPWPGSDYQCSDWATIEAFAAILNKAGYSSPIRTPRGRDILAACGQLKSESEKVRASALRKLSLAAMAGVLSDDDEDETA", "output": "Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity."}]}
+{"id": "function_test_864", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEAPAVCLLPLLLLLWAWAPAPGRASPEALPLVNEDVKRTVDLSSHLAKVTAEVVLAHAGSSSSPRAASFLLALEPELEARLAHLGVQVKGEDEEENNLEVRETKIKGKRGRFFTVTLPVALDPGAKISVTVETVYTHVLQPYPTQITQSEKQFVVFEGNHYFYSPYPTKSQSMRVKLASRNVESYTKLGNPTRSEDLLDYGPFRDVPPYSQDTFKVHSENNSPFLTITSMTRVIEVSHWGNIAVEENVDLKHTGAVLKGPFSRYDYQRQPDSGISSIRSFKTILPAAAQDVYYRDEIGNVSTSHLLILDDSVEMEIRPRFPLFGGWKTHYIVGYNLPSYEYLYNLGDQYALKMRLVDHVFDEQVIDSLTVKIILPEGAKNIQVDSPYEISRAPDELHYTYLDTFGRPVIVAHKKNLVEQHIQDIVVHYTFNKVLMLQEPLLVVAAFYILFFTVIVYVRLDFSITKDPAAEARMKVACITEQVLTLVNKRIGLYRHFDETINRYKQSRDVSTLNSGKKSLELEHKALTSEVALLQSRLKTEGSDLCDKVSEMQKLDAQVKELVLKSAVEAERLVAGKLKKDTYIENEKLISGKRQELVTKIDHILDAL", "output": "Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (Probable). N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity)."}]}
+{"id": "function_test_865", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTATLERRESANLWGRFCEFITSTENRLYIGWFGVIMIPCLLTAISVYIIAFVAAPPVDIDGIREPVSGSLLYGNNIISGSVIPMSNAIGLHFYPIWEAASLDEWLYNGGPYLMVVCHFLLGIACYMGREWELSFRLGMRPWIAVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLIRETTENESANAGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLAVWPVVGIWFTAMGISTMAFNLNGFNFNQSVVDSQGRVINTWADIINRANLGMEVMHERNAHNFPLDLASVEAPAVNG", "output": "Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors."}]}
+{"id": "function_test_866", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MMSFVSLLLVSILFPAIQAKQFTKCELPQVLKDMDGFGGIALPEWICTIFHTSGYDTQTIVNNNGGTDYGLFQISNKFWCKDDQNLQSRNICDISCDKFLDDDLTDDMICAKKILDKEGIDYWLAHKPLCSEKLEQWRCEKL", "output": "Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins."}]}
+{"id": "function_test_867", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGLEKSLMLFPLFVLLLGWVQPSLGRESSAQKFQRQHMDPAGSSSNSPTYCNQMMKRRDMTKGSCKPVNTFVHEPLADVQAICSQENVTCKNGKSNCYKSSSALHITDCHLKGNSKYPNCDYKTSQYQKQIIVACEGNPYVPVHFDATV", "output": "Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single-stranded and double-stranded RNA (By similarity)."}]}
+{"id": "function_test_868", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAVDPFACPMMTMQRKPEVHDAFREAGPVVEVNAPAGGPAWVITDDALAREVLADPRFVKDPDLAPAAWRGVDDGLDIPVPELRPFTLIAVDGEAHRRLRRIHAPAFNPRRLAERTDRIAAIAGRLLTELADASGRSGKPAELIGGFAYHFPLLVICELLGVPVTDPAMAREAVSVLKALGLGGPQSGGGDGTDPAGGVPDTSALESLLLEAVHSARRNDTPTMTRVLYERAQAEFGSVSDDQLVYMITGLIFAGHDTTGSFLGFLLAEVLAGRLAADADEDAVSRFVEEALRYHPPVPYTLWRFAATEVTIGGVRLPRGAPVLVDIEGTNTDGRHHDAPHAFHPDRPSWRRLTFGDGPHYCIGEQLAQLESRTMIGVLRSRFPEARLAVPYDELRWCRKGAQTARLTELPVWLR", "output": "Involved in the biosynthesis of the anthracyclines carminomycin and daunorubicin (daunomycin) which are aromatic polyketide antibiotics that exhibit high cytotoxicity and are widely applied in the chemotherapy of a variety of cancers. In vivo, DoxA catalyzes the C-13 hydroxylation of 13-deoxycarminomycin and 13-deoxydaunorubicin to yield 13-dihydrocarminomycin and 13-dihydrodaunorubicin, respectively, as well as the oxidation of these 13-dihydro-anthracyclines to their respective 13-keto forms, carminomycin and daunorubicin. In vitro, it also catalyzes the C-14 hydroxylation of daunorubicin to form doxorubicin (adriamycin), although this strain is not a doxorubicin producer. It can only use NADP. DoxA acts jointly with DnrV."}]}
+{"id": "function_test_869", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKARGFKTKMRGFKIFSGSAHPAFGKEVSKHLGFPLSKAVIGKFSDGEINIQISESVRGKDIFIIQPTCVPVNDNLMELLVMVDALRRSSANSITAVLPYFGYARQDRKAAPRVPITAKMVANLMQEVGIERIITMDLHAGQIQGFFDVPVDNLYGSIVFRDYIRSKALKNPIIASPDVGGVTRARYFANQMGLDLIIVDKRREKANESEVMNIIGSAKERDVILVDDMIDTAGTICKAALALKEQGATSVMALGTHAVLSGNAIKRIKESALDEVVVTNSIPLVQKCDKITTLSVASLFAEVIRRIYHNESVQSLFT", "output": "Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)."}]}
+{"id": "function_test_870", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQGFFWKTWLVLAVCGTPASLAHRPLSYGEALELAVSVYNGKAGEASLYRLLEAVPQPEWDPSSEGSQQLNFTLKETACQVEEERSLEECGFQEDGVVLECTGYYFFGETPPVVVLSCVPVGGVEEEEEEEEEEQKAEAENDEEVEKEKGDEEKDQPKRVKRFKKFFKKVKKSVKKRLKKIFKKPMVIGVTIPF", "output": "Potent antimicrobial peptide against Gram-negative (P.aeruginosa, K.pneumoniae, E.coli, A.baumannii) . Shows moderate activities against Gram-positive bacteria (E.faecalis, S.aureus, S.pyogenes) . Also shows antifungal activity against standard and clinical isolates of yeasts (MIC=10-40 uM) and dermatophytes (MIC=1-5 uM) . Adopts an amphipathic alpha helical conformation, that may allow to partition into the target membrane . Shows high toxicity towards human fibroblasts (micromolar ranges) . Shows low hemolytic activities on human erythrocytes . Also shows toxicity (micromolar ranges) when tested on many leukemia cell lines . In addition, when tested in vitro on the parasite Trypanosoma cruzi (responsible of the Chagas disease), is able to reduce the number of the three forms (epimastigote, trypomastigote and amastigote) by inducing cell death through necrosis ."}]}
+{"id": "function_test_871", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKMLVEKIEKKFDQEKVIEEFEDLTKDAGKIQEETLKKILEQNGGTEYLQLWGLNGRTDPQTFKNCVPIVTHNDLEPYIQRIADGDLSPILTGKPIETISLSSGTTQGKPKFVPFNDELMESTMQIFKTSFAFRNREFPIGNGKALQFIYSSKQFKTKGGLAAGTATTNVYRNAQFKKTMKAMCTPCCSPDEVIFGPDFHQSLYCHLLCGLIFHDEVQVVSSTFAHSIVHAFRTFEQVWEALVVDIREGVLSSRVTVPSIRLAMSKLLKPDPELADTIYNKCSRLSNWYGLIPDLFPNTRYIYGIMTGSMEPYLKKLRHYAGELPLLSADYGSSEGWVGVNVNPKLPPELVTYAVLPNIGYFEFIPLGGNLNGIEQANSPVGLTEVKLGEEYEVVFTNFAGLYRYRLGDVVKVKGFHNGTPELQFVCRSNLLLSINIDKNTEKDLQLAVEAAAKRLVDEKLEVVDFTSHVNVSADPGHYVIFWELSGEATDEMLQDCCNCLDRSFIDAGYVSSRKVNAIGALELRIVKRGTFHKILDHFVGLGGAVSQFKTPRCVGPKNSSLLQILSSNVVETYVSTAFC", "output": "Catalyzes the synthesis of jasmonate-amino acid conjugates by adenylation . Catalyzes the conjugation of jasmonate (JA) to Ile, Leu and Val . Catalyzes the conjugation of JA to Ile that may mediate defense signaling and resistance to the herbivore Manduca sexta caterpillars ."}]}
+{"id": "function_test_872", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKVTLPEFERAGVMVVGDVMLDRYWYGPTSRISPEAPVPVVKVNTIEERPGGAANVAMNIASLGANARLVGLTGIDDAARALSKSLADVNVKCDFVSVPTHPTITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALSSIGALVLSDYAKGALASVQQMIQLARKAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVVGKCKTEEEIVERGMKLIADYELSALLVTRSEQGMSLLQPGKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAAGNSLEEACFFANAAAGVVVGKLGTSTVSPIELENAVRGRADTGFGVMTEEELKLAVAAARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGDSRPVNPLEQRMIVLGALEAVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSKEVWANGGEVLVLNFEDGCSTTNIIKKIQLDKKG", "output": "Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.; "}]}
+{"id": "function_test_873", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNIVILAAGTGKRMRSALPKVLHPLAGRPLLSHVIDTARALAPSRLVVVIGHGAEQVRAAVAAPDVQFAVQEQQLGTGHAVRQALPLLDPSQPTLVLYGDVPLTRTATLKRLADAATDARYGVLTVTLDDPTGYGRIVRDQAGCVTRIVEQKDASPDELRIDEINTGIVVAPTAQLSMWLGALGNDNAQGEYYLTDVVEQAIEAGFEIVTTQPDDEWETLGVNSKAQLAELERIHQRNLADALLAAGVTLADPARIDVRGTLACGRDVSIDVNCVFEGDVTLADGVTIGANCVIRHAAIAAGARVDAFSHLDGATVGANAVVGPYARLRPGAVLAADAHVGNFVEVKNATLGQGSKANHLTYLGDADIGARVNVGAGTITCNYDGANKFRTVIEDDVFVGSDTQFVAPVRVGRGVTVAAGTTVWKDVAADMLVLNDKTQTAKSGYVRPVKKKS", "output": "Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain."}]}
+{"id": "function_test_874", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MITTQKKKKNRFLPDFDKQSIYSLRYEEMQDWLVEHGQQKFRAKQIFQWLYEKRVDSIDEMTNLSKDLREVLKDNFTMTTLETVVKQESRDGTIKFLFELQDGYTIETVLMRHEYGNSVCVTTQVGCRIGCTFCASTLGGLKRNLEAGEIVSQVLTVQKVLDATDERVSQIVIMGIGEPFENYDEMMDFLKIVNYDNGLNIGARHITVSTSGIIPRIYDFAEEDIQINFAVSLHAANDEIRSKLMPINRAYSIDKLMEAIQYYQEKTNRRITFEYGLFGGVNDQLTHARELAHLIQNLNCHVNLIPVNHVPERNYVKTPKEDIFKFEKELKRLGINATIRREQGSDIDAACGQLRAKERQVETR", "output": "Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. Confers resistance to some classes of antibiotics."}]}
+{"id": "function_test_875", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MVKFLSLTSSVTALLLLSLGANGVAAAATTCTVAKSGSDDTAAITKAFSDCKNGGTVVFSKDTTYNLNGILILSDLKNVNIELAGTIKLPGFDKAVKGLKSYIQLIGTNVKVYGGGVINANHSSVSDISIINSPRAHMGVTNATDVLINNITLHTASTSSLRPKNTDALDVSRSSNVVFQNSKLTVGDDCLAINEEVTNVTLSKITCNGGHGFSVGSLGKGGANQHVKTVRIHDSVCNDCQNGVRIKTWPGGKGSVSDIKFNNVELNNVENPILITTHYCDKNQMNYCTNNDKTSLSISDVVISDITGSASNDGNPIVSINCSTSTPCTDFTLSGVKITKASNTPKNVCVNLDGSSKIAECSA", "output": "Specific in hydrolyzing the terminal glycosidic bond of polygalacturonic acid and oligogalacturonates. Has no activity towards trigalacturonic acid."}]}
+{"id": "function_test_876", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNFLHFLTTSLLLLGGSRLALADSASSAIKIKGNAFFNSDTNERFYVRGVDYQPGGSSTLVDPLADTSICKRDLPYLQGLNINTIRVYQVDNSANHDECMSALQDAGIYVILDLATSSNSISRLDAASSYNAVFLQGIFATIDAFKNYTNVLGFFAGNEVANTAENSATTTWVKAALRDAKEYISKNSDRDIPVGYSAADVAEIRVQCADFFACGNSSVRADFYGMNMYEWCGADSSFTISGYDQRMEEFANYSIPLFLSEYGCNDVTKESDGTPDRPFDEVDAIFSSEMSSVFSGGLVYQYSEEGNNYGLVVIDGDNVTISKNYETLKEKYASAANYTGDGDYSSSPATLTCPADDSYFTSFPLPTMPSEAKGFIESGAGQPLGFNAPSNQEFSANATALVSPGPHSVSTTINTNIVQATISQSSTSGSSSGSSSASTTASSSSVSSGSSISSGSSSMSTSYTSASGSSAHSSGSSSGSSSATSSASTFNLSRFYVFAGILAISGLVFA", "output": "Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall."}]}
+{"id": "function_test_877", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKKILVIGDLIADYYLWGKSERLSPEAPVPVLEVQRESKNLGGAANVANNLISLKAKVFLCGVVGDDLEGEHFISALKARGIDASGILIDKTRCTTLKTRIIAQNQQIARVDKEIKDPLNADLRKKLLDFFTEKIQEIDGVILSDYNKGVLDFELTQAMIALANQHHKLILCDPKGKDYSKYSHASLITPNRTELEHALHLKLDSHANLSKALQILKETYHIAMPLVTLSEQGIAFLEKGELVNCPTIAKEVYDVTGAGDTVIASLTLSLLESMSLKDACEFANAAAAVVVGKMGSALASLEEIALILNQTHPKILSLEKLLETLDQQKIIFTNGCFDLLHKGHASYLQKAKALGDILIVGLNSDASIKRLKGDKRPIVSEKDRAFLLASLSCVDYVVVFEEDTPIKLIQALKPDILVKGADYLNKEVIGSEFAKETHLMEFEEGYSTSAIIEKIKRTCND", "output": "Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.; "}]}
+{"id": "function_test_878", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLTAEEKAAVTGFWGKVNVDVVGAEALGRLLVVYPWTQRFFEHFGDLSSAGAVMGNPKVKAHGKRVLDAFSEGLKHLDDLKGAFAELSELHCNKLHVDPENFRLLGNVLVVVLARNFGGEFTPLVQADFQKVVAGVANALAHRYH", "output": "Involved in oxygen transport from the lung to the various peripheral tissues."}]}
+{"id": "function_test_879", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKLLLLLTISASMLIEGLVNADGYIRGGDGCKVSCVINHVFCDNECKAAGGSYGYCWGWGLACWCEGLPAEREWDYETNTCGGKK", "output": "Depressant insect beta-toxins cause a transient contraction paralysis followed by a slow flaccid paralysis. They bind voltage-independently at site-4 of sodium channels (Nav) and block action potentials, primarily by depolarizing the axonal membrane and suppressing the sodium current. This depressant toxin is active only on insects. It is found in a relatively small amount in the venom, and its activity on insects is 10-fold higher compared to other known depressant toxins."}]}
+{"id": "function_test_880", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MREVISIHVGQGGIQVGNACWELFCLEHGIQPDGQMPSDKTIGGGDDAFNTFFSETGAGKHVPRAVFLDLEPTVIDEVRTGTYRQLFHPEQLISGKEDAANNFARGHYTIGKEIVDLCLDRIRKLADNCTGLQGFLVFNSVGGGTGSGLGSLLLERLSVDYGKKSKLGFTIYPSPQVSTAVVEPYNSILSTHSLLEHTDVAVMLDNEAIYDICRRNLDIERPTYTNLNRLIAQVISSLTASLRFDGALNVDITEFQTNLVPYPRIHFMLSSYAPIISAEKAYHEQLSVAEITNSAFEPANMMAKCDPRHGKYMACSMMYRGDVVPKDVNASIATIKTKRTIQFVDWCPTGFKVGINYQPSTVVPGGDLAKVMRAVCMISNSTAIAEVFSRLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGIETAEGEGEEEGY", "output": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin."}]}
+{"id": "function_test_881", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAANNMVNPAVDPALEDELFAKEVEEVKKWWSDSRWRQTKRPFTAEQIVSKRGNLKIEYASNAQAKKLWKILEDRFAKRDASYTYGCLEPTMVTQMAKYLDTVYVSGWQSSSTASSSDEPGPDLADYPYTTVPNKVGHLFMAQLFHDRKQRQERLSVPKDQREKLANIDYLRPIVADADTGHGGLTAVMKLTKLFIEKGAAGIHIEDQAPGTKKCGHMAGKVLVPIQEHINRLVAIRAQADIMGSDLLCIARTDAEAATLITTTIDPRDHAFILGCTNPDLEPLADLMMKAEAEGKTGAQLQAIEDDWLAKADLKRFDEAVLDVIAKGKFSNAKDLAAKYQAAVKGKQISNREARAIARQLLGQEIFFDWESPRTREGYYRLKGGCDCSINRAISYAPYCDAIWMESKLPDYAQAEEFAKGVHAVWPEQKLAYNLSPSFNWKTAMGRDDQETYIRRLAKLGYCWQFITLAGLHTTALISDQFAKAYSKIGMRAYGELVQEPEIDNGVDVVKHQKWSGATYVDELQKMVTGGVSSTAAMGKGVTEDQFH", "output": "Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2-methylisocitrate."}]}
+{"id": "function_test_882", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSPQTETKASVGFKAGVKDYKLTYYTPEYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEENQYICYVAYPLDLFEEGSVTNMFTSIEGNVFGFKALRALRLEDLRIPPAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEXKGHYLNATAGTCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCRDNGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVGKLEGERDITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREGNEIIREACKWSPELAAACEVWKEIKFEFQAMDTL", "output": "RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site."}]}
+{"id": "function_test_883", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKVGFVGWRGMVGSVLMQRMKEENDFAHIPEAFFFTTSNVGGAAPDFGQAAKTLLDANNVAELAKMDIIVTCQGGDYTKSVFQALRDSGWNGYWIDAASSLRMKDDAIIVLDPVNRDVLDNGLKNGVKNYIGGNCTVSLMLMALGGLFQNDLVEWATSMTYQAASGAGAKNMRELISGMGAVHAQVADALADPAGSILDIDRKVSDFLRSEDYPKANFGVPLAGSLIPWIDVDLGNGQSKEEWKGGVETNKILGRSDNPTVIDGLCVRVGAMRCHSQAITLKLKKDLPVSEIETILAGANDWVKVIPNEKEASIHELTPAKVTGTLSVPVGRIRKLGMGGEYISAFTVGDQLLWGAAEPLRRVLRIVLGSL", "output": "Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate."}]}
+{"id": "function_test_884", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDNEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEADAKTGRETIIVHEIPYQVNKARLIEKIAELVKDKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIISAFVRHRREVVTRRTIFELRKARDRAHILEALAIALANIDPIIELIRRAPTPAEAKAALISRPWDLGNVAAMLERAGDDAARPEWLEPEFGVRDGQYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLEQIAELLHILGSADRLMEVIREEMELIRDQFGDERRTEITANSADINIEDLISQEDVVVTLSHQGYVKYQPLTDYEAQRRGGKGKSAARIKEEDFIDRLLVANTHDTILCFSSRGRLYWMKVYQLPEASRGARGRPIVNLLPLEANERITAILPVREYEEGVNVFMATASGTVKKTALTEFSRPRSAGIIAVNLNDGDELIGVDLTSGSDEVMLFSAAGKVVRFKEDAVRAMGRTATGVRGIKLAGDDKVVSLIIPRGEGAILTVTQNGYGKRTAADEYPTKSRATQGVISIKVTERNGSVVGAVQVDDCDQIMMITDAGTLVRTRVSEISVVGRNTQGVILIRTAEDENVVGLQRVAEPVDDEELDAIDGSVAEGDEDIAPEAESDDDVADDADE", "output": "A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state, and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings. Replenishes negative supercoiling downstream of highly transcribed genes to help control overall chromosomal supercoiling density . E.coli makes 15% more negative supercoils in pBR322 plasmid DNA than S.typhimurium; the S.typhimurium GyrB subunit is toxic in E.coli, while the E.coli copy can be expressed in S.typhimurium even though the 2 subunits have 777/804 residues identical .; "}]}
+{"id": "function_test_885", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "YYTPEYKTKDTDILAAFRMTPQPGVPAEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYDIEPVAGEENQYIAYVAYPLDLFEEGSVTNMLTSIVGNVFGFKALRALRLEDLRIPPAYSKTFMGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFVAEALFKSQAETGEIKGHYLNATAGTCEEMMKRAVFARELGAPIVMHDYLTGGFTANTSLAFYCRDNGLLLHIHRAMHAVIDRQRNHGIHFRVLAKALRMSGGDHIHAGTVVGKLEGEREVTLGFVDLLRDDYIEKDRSRGIYFTQDWVSMPGVFPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRD", "output": "RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site (By similarity)."}]}
+{"id": "function_test_886", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKVLLLLGFIFCSMAAHGKRMERCEFARRIKQLHLDGYHQISLANWVCLAQWESGFDTKATNYNPGDQSTDYGILQINSHYWCDDGKTPHAANECKVRCSELQEDDLVKAVNCAKKIVDQQGIRAWVAWRNKCEGKDLSKYLEGCHL", "output": "Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents."}]}
+{"id": "function_test_887", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAVKKFKPYTPSRRFMTVADFSEITKTEPEKSLVKPLKKTGGRNNQGRITVRFRGGGHKRLYRIIDFKRWDKVGIPAKVAAIEYDPNRSARIALLHYVDGEKRYIIAPDGLQVGQQVVAGPDAPIQVGNALPLRFIPVGTVVHAVELEPKKGAKLARAAGTSAQIQGREGDYVILRLPSGELRKVHGECYATVGAVGNADHKNIVLGKAGRSRWLGRRPHVRGAAMNPVDHPHGGGEGRAPRGRPPASPWGWQTKGLKTRKRRKPSSRFIIARRKK", "output": "One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial (By similarity). Makes several contacts with the 16S rRNA (forming bridge B7b) in the 70S ribosome."}]}
+{"id": "function_test_888", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAPRADKKPAEKKPGAEKTPVAEKAPAEKKPRAGKKLPRDAGAAGDKKKKRAEMSVETYKIYIFRVLKHVHPDIGISSKAMGIMNSFINDIFEKLARESSRLAGYNKKPTISSREIQTAVRLVLPGELAKHAVSEGTKAVTKFTSS", "output": "Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling."}]}
+{"id": "function_test_889", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSEFKNVTAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEYTFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSYIAD", "output": "Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions."}]}
+{"id": "function_test_890", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSKVKESAIVSATSALQPQGPSSSYGLINSFAHQYDRGGANVNGKPSYTVDQAANYLLRDGAAWKDLNKDGTISLSYTFLTKAPSDFYSRGLGTFSQFSDLQKGQAKLAMQSWADVAKVTFTEAASGGDGHMTFGNFSASNGGAAFAYLPFDMPGSHKGESWYLINSSYQVNTTPGTGNYGRQTLTHEIGHVLGLSHPGDYNAGEGNPTYRDATYAQDTRGYSVMSYWSESNTGQNFVKAGGQYYASAPLMDDIAAIQKLYGANYATRSGDTVYGFNSNADRDFYSATSSSSKLVFSVWDGGGNDTFDFSGFTQNQKINLNETSFSDVGGMIGNVSIAKGVTIENAFGGSGNDLLIGNALANVLKGGAGNDIIYGGGGADQLWGGTGADTFVFGAISDSTKAAPDRIMDFTSGQDKIDLSAISAFAVNKLPLQFVNAFTGHAGEAVLSYDQGTNLGSLSIDFTGNSSADFLVTTVGQAAVTDIVV", "output": "Secreted protease which is important for P.entomophila to counteract the local immune response of Drosophila . Can degrade antimicrobial peptides (AMPs), e.g. Diptericin and Cecropin A. Thus, protects P.entomophila from the Drosophila antimicrobial peptides produced by the gut innate immune response, and promotes bacterial persistence in the Drosophila gut and killing of the host . Is responsible for maturation of pro-Monalysin to the active toxin Monalysin, by cleaving its N-terminus ."}]}
+{"id": "function_test_891", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEEMTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL", "output": "Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions."}]}
+{"id": "function_test_892", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKSVLDGLADTTFRTITTDLLYMGPNEVQYEDTKSDLSKLGYYPQKLPLSSYQEKIIDGQSTLHLDSFNATEFYNKSITTFKDGDGNIQCGNNFMDMECFMILTPSQQLVIAALSITLGTFTVLENMLVLCVIFQSRTLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHVFHRIDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLSYKRIVTRTKAVIAFCMMWTIAIVIAVLPLLGWNCKKLKSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHHHAVRMLQRGTQKSIIVHTSEDGKVHITRPDQTRMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKTVKTVFAFCCMLCLLNSTVNPIIYALRSKDLRSAFCSMFPNCEGTAQPLDNSMESDGQNRHAHNSNVHRAAESCIKSTVKIAKVTMSVSTDTSAEAV", "output": "G-protein coupled receptor for cannabinoids (By similarity). Mediates many cannabinoid-induced effects in the central nervous system (CNS), as well as in peripheral tissues (By similarity). Regulates cellular respiration and energy production in response to cannabinoids (By similarity). Signaling typically involves reduction in cyclic AMP (By similarity). May be involved in the control of reproductive function ."}]}
+{"id": "function_test_893", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAQISTTSEHTIQTLERIGAHSHVKGLGLDDQLEPRPSSQGMVGQRAARKAAGLIVKMVQDGRIAGRAILMVGPPSTGKTAIAMGMAQTLGSDVPFTMLSASEVFSLEMSKTEALMQAFRRSIGVRIREEAEVVEGEVVEIQIDRSLTGATKTGKLTIKTTDMETIYELGNKMIDSLQKEKVTAGDVIAIDKASGRITKLGRSFTRARDYDAMGSDTKFVQCPEGELQRRKDVVHTVSLHEIDVINSRTQGFLALFSGDTGEIKPELRDQINIKVGEWREEGKAEIVPGVLFIDEVHMLDIECFSFLNRALESELAPLVIMASNRGICRIRGTRFRSPHGIPIDLLDRVLIISTKPYELADLKQILTIRAAEEEVSLKPEALEVLTRMASETSLRYAINLITTANLAAKRRKADEVEVADVRRVYNLFVDEKRSVQYLKEHAEQFMNESDEYGDIDGLNSGAPIIGRQASAGAVQA", "output": "DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity)."}]}
+{"id": "function_test_894", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNSKGQYPTQPTYPVQPPGNPVYPQTLHLPQAPPYTDAPPAYSELYRPSFVHPGAATVPTMSAAFPGASLYLPMAQSVAVGPLGSTIPMAYYPVSPIYPPGSTVLVEGGYDAGARFGAGATAGNIPPPPPGCPPNAAQLAVMQGANVLVTQRKGNFFMGGSDGGYTIW", "output": "In unstressed cells, promotes SIAH1-mediated polyubiquitination and degradation of the serine/threonine-protein kinase HIPK2, probably by acting as a loading factor that potentiates complex formation between HIPK2 and ubiquitin ligase SIAH1 (By similarity). In response to DNA damage, localizes to the nucleus following phosphorylation by HIPK2 and modulates the expression of a subset of TP53/p53 target genes by binding to TP53 at target gene promoters (By similarity). This limits the expression of a number of cell death-mediating TP53 target genes, reducing DNA damage-induced cell death (By similarity). Enhances the binding of transcription factor TCF7L2/TCF4, a Wnt signaling pathway effector, to the promoters of target genes (By similarity). Plays a role in stress granule formation (By similarity)."}]}
+{"id": "function_test_895", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MWIINWFYDILASLGLLNKHAKLLFLGLDNAGKTTLLHMLKNDRVATLQPTAHPTSEELAIGNNRFTTFDLGGHQQARRLWKDYFPEVSGIVFLVDAKDHERFPESKAELDALLAMEELAKVPFLILGNKIDHPDAVSEDELRHQLGLYQTTGKGKVPLEGIRPIEVFMCSVVMRQGYGEGIRWLSQYV", "output": "Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. Sar1 controls the coat assembly in a stepwise manner. Activated Sar1-GTP binds to membranes first and recruits the sec23/24 complex. These sec23/24-sar1 prebudding intermediates are then collected by the Sec13/31 complex as subunits polymerize to form coated transport vesicles. Conversion to sar1-GDP triggers coat release and recycles COPII subunits (By similarity)."}]}
+{"id": "function_test_896", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQSMRFMILALLVQFLPAWAINDPAKSAAPYHDEFPLFRSANMASPDKLSTGIGFHSFRIPAVVRTTTGRILAFAEGRRHTNQDFGDINLVYKRTKTTANNGASPSDWEPLREVVGSGAGTWGNPTPVVDDDNTIYLFLSWNGATYSQNGKDVLPDGTVTKKIDSTWEGRRHLYLTESRDDGNTWSKPVDLTKELTPDGWAWDAVGPGNGIRLTTGELVIPAMGRNIIGRGAPGNRTWSVQRLSGAGAEGTIVQTPDGKLYRNDRPSQKGYRMVARGTLEGFGAFAPDAGLPDPACQGSVLRYNSDAPARTIFLNSASGTSRRAMRVRISYDADAKKFNYGRKLEDAKVSGAGHEGGYSSMTKTGDYKIGALVESDFFNDGTGKNSYRAIIWRRFNLSWILNGPNN", "output": "Sialidase is able to release sialic acid from a wide variety of natural substrates including bovine salivary mucin, colominic acid, bovine fetuin, a serum glycoprotein containing both alpha-2-6 and alpha-2-3-linkages in a ratio of about 3:2, and glycoproteins and glycolipids from thermally denatured human lung epithelial cells. Does not show any trans-sialidase activity since it is able to remove terminal sialic acid residues but is unable to catalyze their transfer to the acceptor substrate. 2-keto-3-deoxynononic acid (KDN) is the preferred substrate and A.fumigatus can utilize KDN as a sole carbon source."}]}
+{"id": "function_test_897", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MATNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPYINVDPGTMSPIQHGEVFVTVDGAETDLDLGHYERFIRTRMTSSNNFTTGRVYEDIIRRERKGEFLGATIQVIPHITNEIKRRVIEGSKGFDIAIIEIGGTVGDIESQPFLEAIRQLGTEIGRDHTLFMHLTLVPFLGAAGEVKTKPTQHSVKELRSIGIQPDVLVCRSDRSLPATERSKIALFTNVEERAVIGLRDVDSIYKIPSMLKAQSLDDIVTKRFNLDCPEADLHEWEEVLYQESNPNGEVTVGFVGKYVELPDAYKSVNEALAHAGLKNRLTVNIRYIDSQDLETKGTSKLEDVDAILVPGGFGDRGIEGKLIAAKYARENNIPYLGICLGMQVAMIEFARNVAGLTGANSTEFDENCSDPVVGLITEWMDASGQKELRDKHSDLGGTMRLGSQECHLEKGSKALKMYGKETIEERHRHRYEVNNHYIEPLEKAGLKITGYSHDKQLVEILENPKHRWFVAVQFHPEFTSTPRDGHPLFKGFIEAAGEFHKERLG", "output": "Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates."}]}
+{"id": "function_test_898", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNDVTTETYETLKQSVLHTFAQLTGYNVSELSLTSHLENDLGVDSIALAEIAVSLSRQFQLNTPLLIQDINTIKDALDGILQREFQLSEKVEPAAIALSGDADLWLGNLVRQIFASHSGYDVNALALDAEIESDLGIDSVSVASAQGELFNTLQLNSETIIANCNTLSALKQCLAARLVQEKGQDWFEQRGRGQSDSAIDHDADTTAEVTPPTATPVAINAEIGDPRTMRDFVGIEHPDIFHKAREFHLFYQDKKKRQLYFYGMPLETPCKNRAVMFDEATGQHREFLMFGSNSYLGLSNHPEIIHAIQDAASLYGATNTGCRIIAGSNVLHLELERKLAKLKGRDDCIVYPSGYSANLGCISALTSRHDLVFTDAINHMSIQDGCKLAGAQRKIYNHSLTSLEKSLAKYADHPGGKLIVTDGVFSMHGDIVDLPRLMKLAERYGARVLVDDAHSTGVLGKTGAGTSEHFNMKGQVDLELGTMSKALSGLGGYVCGDGDVVEYLRFYSNSYVFAATIPAPVAAGVIASIDVMLREPERLAKLWDNIYYFRTRLLNAGFDLENSDSAIIPIVVGDDAKTLFFGRAVRARGMFCQTVVFPGVSVGDARLRISITSEHTREDLDEAYAILVASALEVGVPVNASAHQEENASVAEA", "output": "Involved in the biosynthesis of 4-methoxy-2,2'-bipyrrole-5-carbaldehyde (MBC), one of the terminal products involved in the biosynthesis of the red antibiotic prodigiosin (Pig). Carrier of the L-malonyl group (malonyl-S-PigH), which is decarboxylated by PigJ to yield a C2 carbanion acetyl-S-PigH. Then the pyrrolyl group of pyrrolyl-S-cysteinyl PigJ intermediate is captured by the C2 carbanion acetyl-S-PigH to yield the pyrrolyl-beta-ketoacyl-S-PigH. In the last step, PigH catalyzes the decarboxylative condensation between the pyrrolyl-beta-ketoacyl (pyrrolyl-beta-ketoacyl-S-PigH) and L-serine to yield 4-hydroxy-2,2'-bipyrrole-5-methanol (HBM)."}]}
+{"id": "function_test_899", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSNSSMSVVILAAGKGTRMYSDLPKVLHPLAGKPMVQHVIDAAMKLGAQHVHLVYGHGGELLKKTLADPSLNWVLQAEQLGTGHAMQQAAPHFADDEDILMLYGDVPLISVDTLQRLLAAKPEGGIGLLTVKLDNPSGYGRIVRENGDVVGIVEHKDASDAQREINEINTGILVANGRDLKRWLSLLDNNNAQGEFYITDIIALAHADGKKIATVHPTRLSEVEGVNNRLQLSALERVFQTEQAEKLLLAGVMLLDPSRFDLRGELTHGRDITIDTNVIIEGHVILGDRVRIGTGCVLKNCVIGDDSEISPYTVLEDARLDANCTVGPFARLRPGAELAEGAHVGNFVEIKKARLGKGSKAGHLSYLGDAEIGAGVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVANGATIGAGTTVTRDVAENELVISRVKQVHIQGWKRPVKKK", "output": "Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain."}]}
+{"id": "function_test_900", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MHRRITGKLVIATHNPGKLAEMRELLAPYGIEAISAGELGLAEPDETGDSFQANARIKAEAAAKAAQLPAFADDSGLAVDALDGAPGIYSARWAGDAKDFAGAMARIERLLQERGATAPERRTAHFVSALCVAWPDGHIEEVEARADGTLVWPPRGTAGFGYDPVFLPEGHSRTFGEMTSIEKHGLPPLGLGLSHRAKAFVKLAEICLAG", "output": "Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions."}]}
+{"id": "function_test_901", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDESVSSLFDLLRKHFPAKEEISRQITVVTSQTEMRMILTEGFKLLSLLIELDSCEVNNCSHNKEDLTVEAILSKDNILTIALPRIVPDGYSLYGNVLILLETFVRVNPSSFEQKYNQDMNKLLSLKNDLQLCGITLVPLVDGRTNYYNKFVDDWVIERFRWLLTQIMKVAKESGESIEELEYQRLVTSLSKLENQSLGFENIIKMPQTGIDYRDKLKARMFANLSNKMKESEINQSLLSLKLAFDEAYNDESHLKKFQKTNKEDLIFKLGQQINLSDEKLSCMSCSSKLFSIVSSITQNRDKLDSHVMSVSNAKLWHHESGIANVNEYLRILSVCNKIKSAKILNTRRNTLLFLDMIVLNFIDDCWKNDPTILFQFKKSGLLVGQLAYFVNDRFFDLLLLKELLSKKLKSSPDWIHRCLCNIRKQEFFDISGVEFWIRQPDYESVEELCCALEPVKPKLQYCRDEDNHENHKLDLADKDNYFTCLSVLSSVCLGLVNSMKTSFTSKMVINEKSPNNFYGEVELKECYCQRFYVSDEITGLLFYQKTGEKSRCYSIGVTMHGSYKYIGSFYCDPKRFFLPIFSQVVLFQMTEEMMSWLPEEPSYKEPVVANLRKLILMLLCNPSKRNQNFLQGMRYFIMAYVNQFHSVELMSKLEVPCKSVSEECVQKLTYNLLVDVLTKGDVNEHMTRKFKFCLNVSYLCHLITKETPDRLTDQIKCFEKFLEPKLKFKSVIINPNLTGDLTEEQEEQLLNSIEKLLGKGLQDINDSSEPGISRELLSMCISAFNRDLLRVNGKLKNDPYKPNFTSTALDLSSNKSVVIPKLDELGNPISKYDYELLVSSCIASMAESFKTKGKYKLDPTSQEFLILKNLYSLMSKSKRDDHMKDSEDSKQNLSSDLENLSEEQVLILEQVKRDVNLALSKMRETKLKEKTEARQSSSGSSLKNQQKRQAELQERLSELWSEFMCMKIITVEVSLHEIKDFDPDLIDHTTLKSMLDKLYNSDLASEFFLEEILNPCPLEFLVKNMTTSSYLEGDLFECFKYTLISAGFDQKLGTYEHKNKTRLGFKYEALKVREEGRMSLRESNSEAIARRLDRSVFSNSALRNLCFYSDESPISYSHVSSDTGKLKFGLSYKEQVGSNRELYVGDLNTKLMTRLIEDFSESVVSNMNYSCLNSEKEFERSVMEMKMSVNLGEMNFSLDHSKWGPYMSPVIFAAFLQGLKLEQGSMCTPVSVEPIITLLSWHIHKVVEVPYNVIHAYMTGMIKRQLGLMSPGESSKTEAFIHRLLVDEREPLSHVMSVLDMGQGILHNTSDLYGLVTEQFINYAMRILYDVSMTSFTSSDDQITMVKLNEDLKDMDNPEVISNWERMINFHTFISSKFNKFVSPKTVIGTFAAEFKSRFFVWGEEVPLLTKFVSAALHNIKCKTPIQLSETIDTISDQCVANGVSVEIVSCISNRTNKLVRYSGFPDNPFLSVENMDVKDWVDGNRGYRLQRNIESHLEVDGCTRFVRQAARKVFRNIKSGKIMEQTLVNLVQEDGDKAFQGFMKSVDVSDDDIKLLQNFRWINLSTHGDMRLVLRTKLMSSRRIIEQEEIPGLIKSIQSKLSKNFVRGAKRILADSINKSAFQSSIASGFIGFCKSMGSKCVRLGGGGFGYIKDIKNKVKHDCLCDICFRWRGCVYCPSSCADVFEFSRPLMWDYFTLVLTNACELGEWVFEDVEIPKDLYFLRNPNLFWLVKPRVTCQLEERLGLSHILQSIRKNYPTLFETHLSPFMSDFMVGKTLGSLTVKFLDLCVALDLANENLGITKHFLKERRHEIYVVKQDESSQSHIRNVKGIESSVELNSMQVCNNFLTQLLMSSFIQPLVLTSSVFKKFNWFAEVLCLKTEEEVCLKQLTDFVLQVKKFNVDRAMHIEDLSAGYISSTINVTSFSLSVPTFLECVDSDFINKEGNEPGDFKDLLSSEFTKDTLTLDFCIQVSHIKRSVKFNVKRTLVYTLAVRTQIEKKIILEAIGTDDQISLIVSELDLFCSGHTGNHFVLDAAPLIYSEPLIAGSLKFDLLSMLRDQELSLTSSEKMPTFNFDFSSQKHHIVNKFAYKLVGPSVYDEPLVLNKGIVYSGERKLTSLGVDVSGERIVQAMGELDSISEQELFLTNLWGYSKETDIKVRIIQDNLKILTDNYFVQLKNSLKTFAEWLNLGNYMLCYSKTLDTIMISDVSGRIKLKGVICRKLIEDEVMEVE", "output": "RNA-dependent RNA polymerase, which is responsible for the replication and transcription of the viral RNA genome using antigenomic RNA as an intermediate. During transcription, synthesizes subgenomic RNAs and assures their capping by a cap-snatching mechanism, which involves the endonuclease activity cleaving the host capped pre-mRNAs. These short capped RNAs are then used as primers for viral transcription. The 3'-end of subgenomic mRNAs molecules are heterogeneous and not polyadenylated. The replicase function is to direct synthesis of antigenomic and genomic RNA which are encapsidated and non capped. As a consequence of the use of the same enzyme for both transcription and replication, these mechanisms need to be well coordinated. These processes may be regulated by proteins N and Z in a dose-dependent manner."}]}
+{"id": "function_test_902", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLSTQAELAAFHSGLGQPLQFVPTMGGLHQGHGELIRRAAEQGPVLVSVFVNPLQFAPGEDFERYPRSLEADLALADRYGAAALWTPTVQTIYPDGATADSARQAPAALQQHLCGADRPGHFDGVVTVVARLLELTRPAGLWLGEKDWQQLVILRQLVADLVLPVKIHGVATVREADGLALSSRNQYLSAAQRLQAAALPAALRAADGTTPLDVTRSRLSAAGLEVEYVERVDPQSLQPCGSETALSLLAAAVRCGTTRLIDHSFLMTRQPLVAIDGPAGAGKSTVTRAFAERLGLIYLDTGAMYRAVTWLVQQQGVEPGDAAAVDALLRALDLQLQSLPGGGQQVMVNGEDVSQAIRSPEVTGSVSVVAAHRCVRQALTTQQKAMGAKGGLVAEGRDIGSAVFPDADLKVFLTATVAERARRRALDLEQRGFPVQERSELEAQIAERDHLDSTREEAPLVQAIDAVELVTDGMSIDAVIDALVEQFRARVPEEAWPTPAG", "output": "Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.; "}]}
+{"id": "function_test_903", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTTEKINLLDFDRKGMRQFFAEELGEKAFRADQVMKWIYHFGVDDFDNMTNINKKLREKLQHKCEIKAPTVAEAQHSSDGTIKWAMKVGDQDVETVYIPEEDRATLCVSSQVGCALECKFCSTAQQGFNRNLKVSEIIGQVWRAAREIGLQKETGRRPITNVVMMGMGEPLLNMKNLIPALEIMLDDLGFGLSKRRVTVSTSGVVSGLDQMTGKIDVALAISLHAPNDKLRSEIMPINDRWDIQDFLASVRRYIASSNANRGKVTVEYVLLDHVNDDMGHARELAELMKDTPCKINLIPFNPYPGSPYKKPSNSRIDRFQKTLMQYEHTVTVRKTRGDDIDAACGQLVGDVIDRTKRTAALKAARGAETIDVKAV", "output": "Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity."}]}
+{"id": "function_test_904", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNSPASVAPILPDTIFRAYDIRGVVEDTLNAETAYWIGRAIGSESLAQNEPNVSVGRDGRLSGPELVQQLIQGLHDSGCHVSDVGLVPTPALYYAANVLAGKTGVMLTGSHNPKDYNGFKIVIAGDTLANEQIQALHERIKTNNLTSQKGSITQVNILDRYFKQIKDDIVMARKLKVVVDCGNGAAGVIAPQLIEALGCEVISLFAEVDGNFPNHHPDPGKLENLQDLIAKVKETGADLGLAFDGDGDRVGVVTNAGNVVYPDRLLMLFALDVLKRNPGADIIFDVKCTRRLTPLISEHGGRPVMWKTGHSLIKKEMKKSGALLAGEMSGHIFFKERWFGFDDGIYSAARLLEILSQEPANAEDLFETFPNDISTPEINIKVTDVTKFSIIEALEKDAQWGDAKLTTIDGVRVDYPKGWGLVRASNTTPVLVLRFEAETQAELERIQGVFHAELKKVAPDLDLPF", "output": "The phosphomannomutase activity produces a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and antibiotics. Also involved in core-LPS biosynthesis due to its phosphoglucomutase activity. Essential for biofilm production (By similarity)."}]}
+{"id": "function_test_905", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MMTMPLSKLFAHASRDPLIRELTLDSRSVRPGDLFLAVPGAKVDGREHIADALARGAAAVAYEEQGANVLPLTDVPLIPVKGLIAQLSDIAGRFYGEPSRQLNLVGVTGTNGKTSVTQLVAQALDLLGQRCGLIGTLGTGFYGELQSGRLTTPDPIAVQSTLNDLKKGGARAVAMEVSSHALEQGRVAALEFDIAVMTNLSRDHLDYHGSMEAYEAAKAKLFAWPSLRCQVVNLDDDFGRRLAADFARRPSVDHIETRLLSYSLESPEASLFCREAVFSDDGVRATLVTAQGERILRSQLLGRFNLSNMLAAVATLLALDYALDEILKVTPQLQGPVGRMQRLGGGDKPLVVVDYAHTPDALEKVLEALRPHAHGKLLCLFGCGGDRDRGKRPLMAEVAERLADRVLVTDDNPRTEDPSRIFDDIRPGFTRPDDVEFVAGRGEAIAHLIATAAANDVIVLAGKGHEDYQEINGERHDFSDLTEAEKALAAWEAPHA", "output": "Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan."}]}
+{"id": "function_test_906", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSKTNESLMQRRVAAVPRGVGQIHPIFVDTAKNSTVIDVEGRELIDFAGGIAVLNTGHLHPKVVAAVQEQLTKVSHTCFQVLAYEPYVELCEKINKLVPGDFDKKTLLVTTGSEAVENAVKIARAATGRAGVIAFTGGYHGRTMMTLGLTGKVVPYSAGMGLMPGGIFRALFPSELHGISVDDAIASVERIFKNDAEPRDIAAIILEPVQGEGGFLPAPKELMKRLRALCDQHGILLIADEVQTGAGRTGTFFAMEQMGVAPDLTTFAKSIAGGFPLAGVCGKAEYMDAIAPGGLGGTYAGSPIACAAALAVIEVFEEEKLLDRSKAVGERLTAGLREIQKKYPIIGDVRGLGSMIAVEVFEKGTHTPNAAAVGQVVAKAREKGLILLSCGTYGNVLRILVPLTAEDALLDKGLAIIEECFAEIA", "output": "Catalyzes the conversion of 5-aminovalerate to 5-oxopentanoate."}]}
+{"id": "function_test_907", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKKPYTIGLDIGTNSVGWAVLTDQYDLVKRKMKIAGDSEKKQIKKNFWGVRLFDEGQTAADRRMARTARRRIERRRNRISYLQGIFAEEMSKTDANFFCRLSDSFYVDNEKRNSRHPFFATIEEEVEYHKNYPTIYHLREELVNSSEKADLRLVYLALAHIIKYRGNFLIEGALDTQNTSVDGIYKQFIQTYNQVFASGIEDGSLKKLEDNKDVAKILVEKVTRKEKLERILKLYPGEKSAGMFAQFISLIVGSKGNFQKPFDLIEKSDIECAKDSYEEDLESLLALIGDEYAELFVAAKNAYSAVVLSSIITVAETETNAKLSASMIERFDTHEEDLGELKAFIKLHLPKHYEEIFSNTEKHGYAGYIDGKTKQADFYKYMKMTLENIEGADYFIAKIEKENFLRKQRTFDNGAIPHQLHLEELEAILHQQAKYYPFLKENYDKIKSLVTFRIPYFVGPLANGQSEFAWLTRKADGEIRPWNIEEKVDFGKSAVDFIEKMTNKDTYLPKENVLPKHSLCYQKYLVYNELTKVRYINDQGKTSYFSGQEKEQIFNDLFKQKRKVKKKDLELFLRNMSHVESPTIEGLEDSFNSSYSTYHDLLKVGIKQEILDNPVNTEMLENIVKILTVFEDKRMIKEQLQQFSDVLDGVVLKKLERRHYTGWGRLSAKLLMGIRDKQSHLTILDYLMNDDGLNRNLMQLINDSNLSFKSIIEKEQVTTADKDIQSIVADLAGSPAIKKGILQSLKIVDELVSVMGYPPQTIVVEMARENQTTGKGKNNSRPRYKSLEKAIKEFGSQILKEHPTDNQELRNNRLYLYYLQNGKDMYTGQDLDIHNLSNYDIDHIVPQSFITDNSIDNLVLTSSAGNREKGDDVPPLEIVRKRKVFWEKLYQGNLMSKRKFDYLTKAERGGLTEADKARFIHRQLVETRQITKNVANILHQRFNYEKDDHGNTMKQVRIVTLKSALVSQFRKQFQLYKVRDVNDYHHAHDAYLNGVVANTLLKVYPQLEPEFVYGDYHQFDWFKANKATAKKQFYTNIMLFFAQKDRIIDENGEILWDKKYLDTVKKVMSYRQMNIVKKTEIQKGEFSKATIKPKGNSSKLIPRKTNWDPMKYGGLDSPNMAYAVVIEYAKGKNKLVFEKKIIRVTIMERKAFEKDEKAFLEEQGYRQPKVLAKLPKYTLYECEEGRRRMLASANEAQKGNQQVLPNHLVTLLHHAANCEVSDGKSLDYIESNREMFAELLAHVSEFAKRYTLAEANLNKINQLFEQNKEGDIKAIAQSFVDLMAFNAMGAPASFKFFETTIERKRYNNLKELLNSTIIYQSITGLYESRKRLDD", "output": "CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity."}]}
+{"id": "function_test_908", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "SRKQKFDKKFIKLVIVVDHSMVXKXNNDLIAI", "output": "Calcium-dependent prothrombin (F2) activator. This protein may activate prothrombin via recognition by the regulatory subunit of the calcium ion bound conformation of its gamma-carboxyglutamic acid (GLA) domain, and the subsequent conversion of prothrombin to active thrombin is catalyzed by the catalytic subunit."}]}
+{"id": "function_test_909", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "GSFELTILHTNDVHARLEQTSRDSGKCTGEDCYGGVARRATKIRQIRASHRNVLLLDAGDQYQGTIWFNYYKGREVVHFMNSLRYDAMALGNHEFDNGLNGLLDPLLKNVKFPILSANIRPKGPIASNISGYILPYKIINVGSEKVGIIGYTTKETPVLSNPGPYLEFRDEVEELQKHADKLTTLGVNKIIALGHSGFMEDCRIAQKVKGVDVVVGGHTNTFLYTGSPPSNEVAAGNYPFMQLSDDGRQVPVVQAYAFGKYLGYLNVTFDDKGKVIKASGNPILLNKSIQEDPAVKAEISRMKVQLQNYSSQEIGRTIVYLNGTTHACRFHECNLGNLICDAVVYNNLRHPDDNEWNHVSMCIVNGGGIRSPIDEQANNGIITLEELTAVLPFGGTFDLLQIKGSTLRQAFEHSVHRHGQGTGELLQVSGIKVVYDLSQKPGKRVVSLNVLCTECRVPTYVPLEMEKTYKVLLPSFLAAGGDGYYMLKGDSSNHSSGDLDISIVGDYIKRMGKVFPAMEGRMVFSAGSL", "output": "Hydrolyzes nucleotides into nucleosides (By similarity). Snake venom 5'-nucleotidases are widely distributed among venomous snake taxa, but there is a lack of information about their biological activities. They have been shown to inhibit platelet aggregation. This effect may be due to the liberation of inhibitory AMP or adenosine by its action on ADP released upon initiation of aggregation. Venom 5'-nucleotidases are also known to synergistically act in vivo with other toxins like ADPases, phospholipases, and disintegrins to exert a more pronounced anti-coagulant effect."}]}
+{"id": "function_test_910", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSEQLVTPENVTTKDGKINLLDLNRQQMREFFKDLGEKPFRADQVMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQRVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVGAAKVTGQRPITNVVMMGMGEPLLNLNNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPNDEIRDEIVPINKKYNIETFLAAVRRYLEKSNANQGRVTIEYVMLDHVNDGTEHAHQLAELLKDTPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVLMSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEAIDIKAV", "output": "Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity."}]}
+{"id": "function_test_911", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAPKAEKKPAEKKPAEEKAGEKAPAAGKKPKAEKRLPASKGEKGGEGKKERGRKKAKKSVETYKIYIFKVLKQVHPDIGISSKAMSIMNSFINDIFEKLAGEAAKLARYNKKPTITSREIQTSVRLVLPGELAKHAVSEGTKAVTKFTSS", "output": "Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling."}]}
+{"id": "function_test_912", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQCIAFHQFASSSSLPIWSSIDNRFTPKTSITSISKPKPKLKSKSNLKSRSRSSTCYSIQCTVVDNPSSTITNNSDRRSANYGPPIWSFDFVQSLPIQYKGESYTSRLNKLEKDVKRMLIGVENSLAQLELIDTIQRLGISYRFENEIISILKEKFTNNNDNPNPNYDLYATALQFRLLRQYGFEVPQEIFNNFKNHKTGEFKANISNDIMGALGLYEASFHGKKGESILEEARIFTTKCLKKYKLMSSSNNNNMTLISLLVNHALEMPLQWRITRSEAKWFIEEIYERKQDMNPTLLEFAKLDFNMLQSTYQEELKVLSRWWKDSKLGEKLPFVRDRLVECFLWQVGVRFEPQFSYFRIMDTKLYVLLTIIDDMHDIYGTLEELQLFTNALQRWDLKELDKLPDYMKTAFYFTYNFTNELAFDVLQEHGFVHIEYFKKLMVELCKHHLQEAKWFYSGYKPTLQEYVENGWLSVGGQVILMHAYFAFTNPVTKEALECLKDGHPNIVRHASIILRLADDLGTLSDELKRGDVPKSIQCYMHDTGASEDEAREHIKYLISESWKEMNNEDGNINSFFSNEFVQVCQNLGRASQFIYQYGDGHASQNNLSKERVLGLIITPIPM", "output": "Involved in monoterpene (C10) olefins biosynthesis."}]}
+{"id": "function_test_913", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSSLRPEEARKLATAASVSPLSNCQFSGVVISSIADEQKLEFTNKYKGSCTLLCSYDSQGVVLRVVSDDDQSHVLKEYMIAADTDAAQMGRRSYAVSLDADNLVLRFASDQDQQLFRKVVENVKHLRPKSVFSQRTEESSASQYFQFYGYLSQQQNMMQDYVRTSTYQRAILGNAVDFQDKIVLDVGAGSGILSFFAVQAGAAKVYAIEASNMAQYAQQLVESNNVQHKISVIPGKIEEIELPEKVDVIISEPMGYMLYNERMLETYLHARKWLKPQGKMYPTHGDLHIAPFSDESLYSEQYNKANFWYQSAFHGVDLTTLHKEGMKEYFRQPIVDTFDIRICMAKSVRHVCDFLNDKEDDLHLISIPLEFQILQTGICHGLAFWFDVEFSGSSQNVWLSTSPTAPLTHWYQVRCLLPMPIFIKQGQTLTGRVLLEANRRQSYDVTIDLHIEGTLISSSNTLDLKNPYFRYTGAPVQAPPGTSTQSPSEQYWTQVDTQGSRNSSSMLNGGLSVNGIGDGMDITHGLMHPH", "output": "Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in proteins. May methylate histone H3 at 'Arg-17' and activate transcription via chromatin remodeling (By similarity)."}]}
+{"id": "function_test_914", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGRFTKNIVLYLLIIAAFVIAIDAFSGQSANKSELSYTGFIQQVQQKKVESVTITNDHGIKGKLKNGTEFNSYAPTDETLIKTLQDNGVEITAAPPEQPAWWMSLLGSAIPIIILVVLFFFIMQQTQGGGGRVMNFGKSRAKLMGEGNVKVSFKDVAGAEEAKQELEEVVEFLKDPGKFTTIGAKIPKGVLLAGPPGTGKTLLAKAVAGEAGVPFFTISGSDFVEMFVGVGASRVRDLFTQAKKNAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLNQLLVEMDGFGANEGIITIAATNRPDILDPALLRPGRFDRQVIVGRPDLRGREAILKVHARNKPLADDVDLKIIAKKTPGFTGADLSNLLNEAALLAARLNKKVITMAEVEEASEKVSMGPERRSHIVSDKDRKLTAYHESGHAIVAHLLPHADPVHKVTIIPRGAAGGYTMMLPTEEQNYKTKSQLLADIRVALGGRIAEALILDEISTGASGDLQSVTNTARAMVTRWGMSDELGPIVFGEQQEQIFLGKNLGHERNYSEEIAAKIDSEIHRIVEEAYKDVTKLLSDNEKFLHDMANALLEEETIDAKAVDNLYKYGTTKEPEAEEPKVASEADSSIVPEGVDAKKTTSTVADLSEASSNEIK", "output": "Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins."}]}
+{"id": "function_test_915", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSALNSRTVEEVRKDYAKLLDPQEPLDSRMRELYRLKEDCLKTAAGVTVILETIDTTDSVLLQHELAYNAGQSGREEAVPELERILRTTSYDVVTRHEAAEALGAIGSPLALQVLEAHSDPTTEPEAPIRETCELALARIAMKETKGDAAVAPPSGCEFVSVDPSPAFSALYSSTDEPVPHTVEELEAVLLDTSGRTRLFRRYMAMFTLRNLATEAAVAALCRGLREDNVSALFRHEVAFVLGQLERPSSQPALIAALKDEEEAPMVRHEAAEALGAIADPATLPVLESYATHHEPIVRDSCVVALEMHKYWANFNGLAHQQQQEA", "output": "Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A. This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function."}]}
+{"id": "function_test_916", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRKKLFSLALIGIFGLVVTNFGTKVDAATRSYGNGVYCNNSKCWVNWGEAKENIAGIVISGWASGLAGMGH", "output": "Bacteriocin that inhibits the growth of wide range of Gram-positive bacterial species. Does not inhibit the growth of several strains of Gram-negative bacteria."}]}
+{"id": "function_test_917", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNGTEGLNFYVPFSNKTGVVRSPFEYPQYYLAEPWQFSVLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYIPLNLAVANLFMVFGGFTTTLYTSLHAYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGLALTWVMAMACAAPPLVGWSRYIPEGMQCSCGIDYYTSRQEVNNESFVIYMFVVHFTIPLVIIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVVAFLICWVPYASVAFYIFTHQGSDFGPIFMTIPSFFAKSSSIYNPVIYIMMNKQLRNCMLTTLCCGRNPLGDDEASTTASKTETSQVAPA", "output": "Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity)."}]}
+{"id": "function_test_918", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRDRLKDPVKIFEINKGKRPVHIAAPMVRYSKLPFRQLVRDYNTDIVYTPMILAKEFLHPKGRYFDFSTNDADASLILQFGVDDPVILEKAAQLVGPYVDGIGINCGCPQTWAIQEGIGSALLDEPEKVHKLVRAVKSTLGESFCTEVKIRIAKDLNKTRHLMQVIEKSGADIITVHGRTRQDRSSFPVNLDAIREVRPCVQIPVVANGDVKSLRKGLEIAKYTETQGIMSARGLLENPALFAGYEETPWGCVERFLWYSTSYSLNFHLFYHHLTTMMGQMTTKRERMTIPKDSFASVMDWLDEHFVVRRPDEPMFGESVLPCRRY", "output": "Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs . Also able to mediate dihydrouridylation of some mRNAs, thereby affecting their translation ."}]}
+{"id": "function_test_919", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSSGGLLLLLGLLTLCAELIPVSSRQRHRDCDKPPDKGNCGPVRRAFYYDTRLKTCKAFQYRGCNGNGNHFKTETLCRCECLVYP", "output": "Beta-1-bungarotoxin is a presynaptic neurotoxin of the venom. The B chain is homologous to venom basic protease inhibitors but has no protease inhibitor activity and blocks voltage-gated potassium channels (Kv) (By similarity)."}]}
+{"id": "function_test_920", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "KKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADEKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHSTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKENREATEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRVKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYADRIERMLRLSLNIDPEAQVEEEPEEEPEDTTEDTEQDEEEEVDAGTEEEEEEEQETAKESTAEKDEL", "output": "Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. May participate in the unfolding of cytosolic leaderless cargos (lacking the secretion signal sequence) such as the interleukin 1/IL-1 to facilitate their translocation into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and secretion; the translocation process is mediated by the cargo receptor TMED10 (By similarity)."}]}
+{"id": "function_test_921", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKKTKFFLLGLAALAMTACNKDNEAEPVTEGNATISVVLKTSNSNRAFGVGDDESKVAKLTVMVYNGEQQEAIKSAENATKVEDIKCSAGQRTLVVMANTGAMELVGKTLAEVKALTTELTAENQEAAGLIMTAEPKTIVLKAGKNYIGYSGTGEGNHIENDPLKIKRVHARMAFTEIKVQMSAAYDNIYTFVPEKIYGLIAKKQSNLFGATLVNADANYLTGSLTTFNGAYTPANYANVPWLSRNYVAPAADAPQGFYVLENDYSANGGTIHPTILCVYGKLQKNGADLAGADLAAAQAANWVDAEGKTYYPVLVNFNSNNYTYDSNYTPKNKIERNHKYDIKLTITGPGTNNPENPITESAHLNVQCTVAEWVLVGQNATW", "output": "Structural subunit of the major fimbriae . These long, filamentous pili are attached to the cell surface; they mediate biofilm formation, adhesion onto host cells and onto other bacteria that are part of the oral microbiome. They play an important role in the invasion of periodontal tissues . Fimbriae and their constituents are major virulence factors. FimA proteins from different strains have highly divergent sequences, and this has been used for classification. The sequence-based classification correlates with pathogenicity."}]}
+{"id": "function_test_922", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MITIEQLLDILKKDHNFREVLDADEYHYHYQGFSFERLSYDSRQVDGKTLFFAKGATFKADYLKEAITNGLQLYISEVDYELGIPVVLVTDIKKAMSLIAMAFYGNPQEKLKLLAFTGTKGKTTAAYFAYHMLKESYKPAMFSTMNTTLDGKTFFKSQLTTPESLDLFAMMAECVTNGMTHLIMEVSSQAYLVDRVYGLTFDVGVFLNISPDHIGPIEHPTFEDYFYHKRLLMENSRAVVINSVMDHFSFLADQVADQEHVFYGPLSDNQITTSQAFSFEAKGQLAGHYDIQLIGHFNQENAMAAGLACLRLGASLADIQKGIAKTRVPGRMEVLTMTNHAKVFVDYAHNGDSLEKLLSVVEEHQTGKLMLILGAPGNKGESRRADFGRVIHQHPNLTVILTADDPNFEDPEDISKEIASHIARPVEIISDREQAIQKAMSLCQGAKDAVIIAGKGADAYQIVKGQQVAYAGDLAIAKHYL", "output": "Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan."}]}
+{"id": "function_test_923", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLSKSGIERTQWGRRVVRWRGDGVAAYIVAAIVTSSVLAIRMIRAEPIGEGLLLFSFIPAILVVALIGGRNPILFAAGLSLVAAVSHQQISSADGPSVVELLVFGSAVLLIVALGEVLEAARRAIDRTEDVVRARDAHLRSILDTVPDATVVSATDGTIVSFNAAAVRQFGYAEEEVIGQNLRILMPEPYRHEHDGYLQRYMATGEKRIIGIDRVVSGQRKDGSTFPMKLAVGEMRSGGERFFTGFIRDLTEREESAARLEQIQAELARLARLNEMGEMASTLAHELNQPLSAIANYSHGCTRLLRDMDDAVATRIREALEEVASQSLRAGQIIKHLREFVTKGETEKAPEDIRKLVEESAALALVGSREQGVRTVFEYLPGAEMVLVDRIQVQQVLINLMRNAIEAMRHVDRRELTIRTMPADPGEVAVVVEDTGGGIPEEVAGQLFKPFVTTKASGMGIGLSISKRIVEAHGGEMTVSKNEAGGATFRFTLPAYLDERIVAND", "output": "Putative oxygen sensor; modulates the activity of FixJ, a transcriptional activator of nitrogen fixation fixK gene. FixL probably acts as a kinase that phosphorylates FixJ."}]}
+{"id": "function_test_924", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKSNWKITAFLYMCSFLGSFISATYQQQSRLPVILGARQRTDLCPTIRIGEDDLPGFDLISQFQIEKAASQGIVQRVVGSTALQVAYKLGPNVDFRIPTSAIYSNGLPDEYSFLTTFRMTGATLQKYWTIWQIQDSSGKEQVGVNLNGPMKSVEFSYKGVDGSLQTASFLHLPFLFDSQWHKLMISVETTSVTLFIDCIKVETLNIKPKGKISVDGFSVLGRLKNNPQISVPFEVQWMPIHCDPLRPQREGCGELPARISQTVIERGLPGPPGPPGPPGPPGVPGIDGIDGERGPNGPPGPPGPDGDAGKAGSPGLPGEPGADGLTGPDGSPGATGPKGQKGEPGPPGARGLPGKGLLGPPGPAGAAGLPGEVGRAGPPGDPGKRGPPGPPGPPGPRGTIGLQDGDPLCPNACPPGRPGHAGLMGMKGQKGSKGESGELGKQGYKGEEGGQGPIGEVGAQGPLGIPGIRGITGITGPKGNKGARGLDGGPGPQGLPGAPGGQGQRGPVGEEGPKGERGPQGTRGINGLPGPKGESGLPGVDGREGIPGMPGAKGEPGKPGTPGDTGPPGLPGLPGSPGMKGIPGPKGNRGPPGVPGLMGNSGKPGEQGPEGEAGPTGPRGPPGSRGEPGPAGPPGLPGKWGPQGDIGLPGLPGPPGLPGGKGDRGSAGEPGPKGEQGAPGSEGDAGEKGDLGDMGLPGAKGSVGNPGDPGSRGPEGSRGLPGMEGPRGAPGPRGLQGEQGAPGLPGSQGPAGKEPTDQHIKQVCMRVMQEQLSQLAASLRRPEFGAPGLPGRPGPPGAPGPPGENGFPGQLGPRGLPGLKGPPGEIGRKGPKGEAGERGERGFPGRGVKGLPGPRGLPGEPGKPSYGREGRDGVRGPPGVAGQPGIPGPPGPPGPPGYCEPSSCRMQAGQRAAGKNMKGP", "output": "Structural component of hyaline cartilage and vitreous of the eye."}]}
+{"id": "function_test_925", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDRAVSQVALENDEREAKNTWRLIFRIAILFLTVVTLAISVASLLYSMGASTPSDLVGIPTRISRAEEKITSTLGSNQDVVDRIYKQVALESPLALLNTETTIMNAITSLSYQINGAANNSGWGAPIHDPDYIGGIGKELIVDDASDVTSFYPSAFQEHLNFIPAPTTGSGCTRIPSFDMSATHYCYTHNVILSGCRDHLHSHQYLALGVLRTSATGRVFFSTLRSINLDDTQNRKSCSVSATPLGCDMLCSKATETEEEDYNSAVPTRMVHGRLGFDGQYHEKDLDVTTLFGDWVANYPGVGGGSFIDSRVWFSVYGGLKPNTPSDTVQEGKYVIYKRYNDTCPDEQDYQIRMAKSSYKPGRFGGKRIQQAILSIKVSTSLGEDPVLTVPPNTVTLMGAEGRILTVGTSHFLYQRGSSYFSPALLYPMTVSNKTATLHSPYTFNAFTRPGSIPCQASARCPNSCVTGVYTDPYPLIFYRNHTLRGVFGTMLDGEQARLNPASAVFDSTSRSRITRVSSSSIKAAYTTSTCFKVVKTNKTYCLSIAEISNTLFGEFRIVPLLVEILKDDGVREARSG", "output": "Mediates the viral entry into the host cell together with fusion/F protein. Attaches the virus to sialic acid-containing cell receptors and thereby initiates infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion.; "}]}
+{"id": "function_test_926", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAGSSLACCLLGLLALTSACYIQNCPLGGKRAVLDLDVRTCLPCGPGGKGRCFGPSICCGDELGCFVGTAEALRCREENYLPSPCQSGQKPCGSGGRCAAAGICCSPDGCHADPACDPEAAFSQH", "output": "Neurophysin 1 specifically binds oxytocin.; "}]}
+{"id": "function_test_927", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MASCGIGSCAFAGGQISSLKPHTNQLLGVGAGVHGEARVTMRKATTKKLTASASTSPWYGPDRVLYLGPFSGEPPSYLTGEFPGDYGWDTAGLSADPENFAKNRELEVIHCRWAMLGALGCVFPELLARNGVKFGEAVWFKAGAQIFSEGGLDYLGNPSLVHAQSILAIWACQVILMGAVEGYRIAGGPLGEVTDPIYPGGSFDPLGLAEDPEAFAELKVKEIKNGRLAMFSMFGFFVQAIVTGKGPIENLADHLADPVNNNAWAYATNFVPGK", "output": "The light-harvesting complex (LHC) functions as a light receptor, it captures and delivers excitation energy to photosystems with which it is closely associated."}]}
+{"id": "function_test_928", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNKVFDKLKPVFEAIAANKYISAIRDGFIACMPIIIFSSIFMMVAYVPNAWGFYWPDNVTNTLMVAYNYSMGLLALFVAGTTAKNLTDSKNLELPKTNQINPVAVIVASEISFVILSILPLKTGVDLTYMGTQGLICAYIVGLIVPNIYYVCIKNNVTIKLPEQVPGNIAQSFKDLIPMGLSVTAFWLFGVGFKAATGTVLPRWIIQVLSPLFQASDSYLGLALIAGAMAFFWFCGVQGPSIVQPAVVPIMIANTAANLQQYQAGQHVSHVLAMNTMDYVMNFGGTGATLVVPFIMLFAARSAQLKAVGKAAFVPCTFGVNEPVLFGMPIIMNPMLFIPFLATPIVNVCLFKFFVSVLGMNSMMYTMPWTVPGPIGILISTGFAPLAFVFVLLTLVLDVAIYFPFIRVYDSTLLAEEKAKEEVIEDDGMAVLASDTVSPSIPTGLTVATATDDDATHVLPETAPSAHGEAYFKQNEVDVLVLCAGGGTSGILANALNKLSKERGLKLSAAARAYGQDMDLIKDMNMVILAPQMESMKGNLKKITDKYGVKLVTTTGRQYIELTNNGDMALDFVESNL", "output": "The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II LacEF PTS system is involved in lactose transport."}]}
+{"id": "function_test_929", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKIILWLCVFGLFLATLFPISWQMPVESGLSSEDSASSESFASKIKRHGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPSG", "output": "Venom protein that mimics the incretin hormone glucagon-like peptide 1 (GLP-1). It stimulates insulin synthesis and secretion, protects against beta-cell apoptosis in response to different insults, and promotes beta-cell proliferation. It also promotes satiety, reduces food intake, reduces fat deposition, reduces body weight and inhibits gastric emptying. Interacts with GLP-1 receptor (GLP1R). Induces hypotension that is mediated by relaxation of cardiac smooth muscle."}]}
+{"id": "function_test_930", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVASWLLSTLTFALVLLIKETSTWTYHFSAENMTYDEASAYCQQNYTHLVAIQNKEEIDYLNSILDYSPSYYWIGIRKVNNVWIWVGTHKPLTEGAKNWAPGEPNNKQNNEDCVEIYIKRPKDTGMWNDERCSKKKLALCYTAACTEASCSGHGECIETINNYSCKCYPGFSGLKCEQVVTCEAQVQPQHGSLNCTHPLGNFSYNSSCSVSCERGYLPSSTETTWCTSSGEWSAPPATCKVVECDTMGKPANGDVKCSPSQGSAPWNTTCTFDCEEGFTLLGARSLQCTSSGSWDNEKPTCKAVSCDTIHHPQNGSVSCSNSSEGKFTFRSSCNFTCEENFLLRGPAQVECTAQGQWTQQAPVCEAVKCDPVHTLEDGFVKCTHPHTGEFTYKSSCTFNCREGFELHGSAQLECTSQGQWAQELPSCQVVQCPSLAVLGKTNVSCSGEPVFGTVCNFACPEGWTLNGSAALMCGAEGQWSGMLPTCEEPIASNVPLAVGLSVSGTSFLTLTSFLLWFLKYFRKKAKKFVPASSRYVGLEAHGNCQVPSHLI", "output": "Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with SELPLG/PSGL1. May have a role in capillary morphogenesis."}]}
+{"id": "function_test_931", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "VGFKAGVKDYKLTYYTPDYETKDTDILAAFRVTPQPGVPPEEAGAAVAAESSTGTWTTVWTDGLTSLDRYKGRCYHIEPVAGEETQFIAYVAYPLDLFEEGSVTNMFTSIVGNVFGFKALRALRLEDLRIPTAYTKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEAIYKAQAETGEIKGHYLNATAGTCEDMMKRAVFARELGVPIVMHDYLTGGFTANTTLAHYCRDNGLLLHIHRAMHAVIDRQKNHGMHFRVLAKALRMSGGDHIHAGTVVGKLEGEREITLGFVDLLRDDFIEKDRSRGIYFTQDWVSLPGVLPVASGGIHVWHMPALTEIFGDDSVLQFGGGTLGHPWGNAPGAVANRVALEACVQARNEGRDLAREDNEIIREASKWSPELAAACEIWKEIKFEF", "output": "RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site."}]}
+{"id": "function_test_932", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKHIKNEREEVFLEDDQAQHSQAELLSSKDENLQPSIPLSPVAFELDFSGNFQFISDNSSELLDIPKDKIIGHSVAEVLGTDGYNAFMRAVNCLLKDDSHSYHVRFQHSINANHANQNYYTAKGDLPSDEKITKPFDAIGILIRHPGSAIPAHTMWVVNPATNSLGSVSPLVTKLLDVIGFGASLLDKYLCDLRTSYHKHNSLDALPLPTPEFCQICEREIQSWFFELHSKFCLSTSTYESVVQAAQDSLLYFRSTLLEIQEGMQKDSSLVPVYKNEPLIVDADDYFFTDENKQTLSLCSFLSQVMYYLEVAIDITIPPVKIIVNFDKVDSLRVQSPRSEKATIELDNYNPSLENCSSAVIALWEDIKTAVDTKITGVLRLRNAIYYSERIRLEIDHHVQEIIDDVVSNLVTNHSSTSLGHLESKLAPSITFPDACDALEAEECITRPGSATNTPQSDRSLDINDLSRSSSYSRHLSHVSLSNPDFAIGSPMSQDSSNYSSPLHRRKASDSNFSDPRFDDLKYLSPNSSPRFVASDGPNRPASNGRSSLFSRGRASNLGDVGLRLPSPSPRIHTIVPNSAPEHPSINDYKILKPISKGAFGSVYLAQKRTTGDYFAIKILKKSNMIAKNQVINVRAERAILMSQGESPFVAKLYYTFQSKDYLYLVMEYLNGGDCGSLLKTMGVLDLDWIRTYIAETVLCLGDLHDRGIIHRDIKPENLLISQNGHLKLTDFGLSRVGYMKRHRRKQSSSIPVLDLRDRSSAISDLSLSTASSVLEAQSLITPERPKRPSLNEKLLSLDGTSIRLAGQSFNYENSAEDSPTATNTPTSQVDESNIFRSTDSPRVQPFFENKDPSKRFIGTPDYIAPEVILGNPGIKASDWWSLGCVVFEFLFGYPPFNAETPDQVFQNILARRINWPAEVFTAESSVALDLIDRLLCMNPANRLGANGVEEIKAHPFFKSVNWDTILEEDPPFVPKPFSPEDTVYFDSRGLKGFDFSEYYNQPTVTEAQKLEEERPASSIPQHVSGNRKGRLRSNTISTPEFGSFTYRNLDFLNKANRNTIQKLRKEHMAVKSAKTSVDDTFSQYMSRFKAKLSTSQSVGPVKSSRRASMADYEASTTTRVQDITTDSIDSIDDFDSLKEGRMLSFFDNLALEDHKGVSSTMSASQSQSSMHTALPDVTEGTSSDEHTTIQKGRIDNLQAQSLTHKRNAISYPGLFQLDRLQMIIPKDEIELAEILKKIFPKLTLVLIDDPWSILKKLLQNEQFNVVFLHFGNDKVSSSRLMYSVRTSATINSRVPFVYICEDETCIPTDLQSDGVLLKPITCENIESCLRKLDVWHS", "output": "May facilitate the progression of anaphase through direct or indirect interaction with the cut8 protein."}]}
+{"id": "function_test_933", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKKNLKRGELTKLKLVERWSATFTLAAFILFNSSFKVLAADKKVENSNNGQITREINADQISKTELNNEVATDNNRPLGPSIAPSRARNNKIYTFDELNRMNYSDLVELIKTISYENVPDLFNFNDGSYTFFSNRDRVQAIIYGLEDSGRTYTADDDKGIPTLVEFLRAGYYLGFYNKQLSYLNTPQLKNECLPAMKAIQYNSNFRLGTKAQDGVVEALGRLIGNASADPEVINNCIYVLSDFKDNIDKYGSNYSKGNAVFNLMKGIDYYTNSVIYNTKGYDAKNTEFYNRIDPYMERLESLCTIGDKLNNDNAWLVNNALYYTGRMGKFREDPSISQRALERAMKEYPYLSYQYIEAANDLDLNFGGKNSSGNDIDFNKIKADAREKYLPKTYTFDDGKFVVKAGDKVTEEKIKRLYWASKEVKAQFMRVVQNDKALEEGNPDDILTVVIYNSPEEYKLNRIINGFSTDNGGIYIENIGTFFTYERTPEESIYTLEELFRHEFTHYLQGRYVVPGMWGQGEFYQEGVLTWYEEGTAEFFAGSTRTDGIKPRKSVTQGLAYDRNNRMSLYGVLHAKYGSWDFYNYGFALSNYMYNNNMGMFNKMTNYIKNNDVSGYKDYIASMSSDYGLNDKYQDYMDSLLNNIDNLDVPLVSDEYVNGHEAKDINEITNDIKEVSNIKDLSSNVEKSQFFTTYDMRGTYVGGRSQGEENDWKDMNSKLNDILKELSKKSWNGYKTVTAYFVNHKVDGNGNYVYDVVFHGMNTDTNTDVHVNKEPKAVIKSDSSVIVEEEINFDGTESKDEDGEIKAYEWDFGDGEKSNEAKATHKYNKTGEYEVKLTVTDNNGGINTESKKIKVVEDKPVEVINESEPNNDFEKANQIAKSNMLVKGTLSEEDYSDKYYFDVAKKGNVKITLNNLNSVGITWTLYKEGDLNNYVLYATGNDGTVLKGEKTLEPGRYYLSVYTYDNQSGTYTVNVKGNLKNEVKETAKDAIKEVENNNDFDKAMKVDSNSKIVGTLSNDDLKDIYSIDIQNPSDLNIVVENLDNIKMNWLLYSADDLSNYVDYANADGNKLSNTCKLNPGKYYLCVYQFENSGTGNYIVNLQNK", "output": "Clostridial collagenases are among the most efficient degraders of eukaryotic collagen known; saprophytes use collagen as a carbon source while pathogens additionally digest collagen to aid in host colonization. Has both tripeptidylcarboxypeptidase on Gly-X-Y and endopeptidase activities; the endopeptidase cuts within the triple helix region of collagen while tripeptidylcarboxypeptidase successively digests the exposed ends, thus clostridial collagenases can digest large sections of collagen (By similarity)."}]}
+{"id": "function_test_934", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAKIVKVIGREIIDSRGNPTVEAEVHLXGGFVGLAAAPSGASTGSREALELRDGDKSRFLGKGVLKAVAAVNNEIAQAIVGKDATNQAEIDQIMIDLDGTENKSNFGANAILAVSLANAKAAAASKGLPLYAYIAELNGTAGVYSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLREALRIGAEVFHNLAKVLKAKGMSTAVGDEGGFAPNLASNADALACIKEAVEKAGYVLGKDVTLAMDCASSEFYNKENGMYEMKGEGKSFTSQEFTHYLEELCKEYPIVSIEDGQDESDWEGFAYQTKVLGDRVQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRIAKYNQLIRIEEALERAGTPAAFPGLKAVKGQA", "output": "Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis."}]}
+{"id": "function_test_935", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MCVSRRRNSGRPILRVRAPHLLRARPHRRSKLKHRRISRKRATLAGSAVVALVAAGFTFQTANASDDVPAFGAKTLSADAAGKLATTLDRDLGADAAGSYYDATAKTLVVNVVDEAGAEQVRQAGGKARIVENSLAELKSARGTLTEKATIPGTSWAVDPVSNKVLVTADSTVDGAAWKKLSAVVEGLGGKAELNRTAGEFTPLIAGGDAIWGSGSRCSLGFNVVKGGEPYFLTAGHCTESVTSWSDTQGGSEIGANEGSSFPENDYGLVKYTSDTAHPSEVNLYDGSTQAITQAGDATVGQAVTRSGSTTQVHDGEVTALDATVNYGNGDIVNGLIQTTVCAEPGDSGGALFAGDTALGLTSGGSGDCSSGGTTFFQPVPEALAAYGAEIG", "output": "Has a primary specificity for large aliphatic or aromatic amino acids."}]}
+{"id": "function_test_936", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGLTSQLLPPLFFLLACAGNFVHGHKCDITLQEIIKTLNSLTEQKTLCTKLTITDILAASKNTTEKETFCRAATVLRQFYSHHEKDTRCLGATAQQFHRHKQLIRFLKRLDRNLWGLAGLNSCPVKEANQSTLENFLERLKTIMREKYSKCSS", "output": "Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4."}]}
+{"id": "function_test_937", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "LFECSFSCEQEKEGDKPCKKKKCKGGWKCKFNMCVKV", "output": "Lethal neurotoxin that blocks neuromuscular transmission. Acts cooperatively to potentiate the activity of huwentoxin-I."}]}
+{"id": "function_test_938", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNPNQKLFASSGIAIALGIINLLIGISNMSLNISLYSKGENHKSDNLTCTNINQNNTTMVNTYINNTTIIDKNTKMENPGYLLLNKSLCNVEGWVVIAKDNAIRFGESEQIIVTREPYVSCDPLSCKMYALHQGTTIRNKHSNGTTHDRTAFRGLISTPLGNPPTVSNSEFICVGWSSTSCHDGVSRMTICVQGNNENATATVYYNKRLTTTIKTWAKNILRTQESECVCHNSTCVVVMTDGPANNQAFTKVIYFHKGTIIKEEPLKGSAKHIEECSCYGHNQRVTCVCRDNWQGANRPVIEIDMNNLEHTSRYICTGVLTDTSRPKDKAIGECFNPITGSPGAPGIKGFGFLNENNTWLGRTISPKLRSGFEMLKIPNAGTDPDSKIKERQEIVGNDNWSGYSGSFIDYWNDNSECYNPCFYVELIRGRPEEAKYVEWTSNSLIALCGSPIPVGSGSFPDGAQIKYFS", "output": "Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates. Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release. Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface. These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell. Otherwise, infection would be limited to one round of replication. Described as a receptor-destroying enzyme because it cleaves a terminal sialic acid from the cellular receptors. May facilitate viral invasion of the upper airways by cleaving the sialic acid moieties on the mucin of the airway epithelial cells. Likely to plays a role in the budding process through its association with lipid rafts during intracellular transport. May additionally display a raft-association independent effect on budding. Plays a role in the determination of host range restriction on replication and virulence. Sialidase activity in late endosome/lysosome traffic seems to enhance virus replication."}]}
+{"id": "function_test_939", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MFDILWNVGWSNGPPSWAEMERVLNGKPRHAGVPAFDADGDVPRSRKRGAYQPPGRERVGSSVAYAELHAHSAYSFLDGASTPEELVEEAARLGLCALALTDHDGLYGAVRFAEAAAELDVRTVFGAELSLGATARTERPDPPGPHLLVLARGPEGYRRLSRQLAAAHLAGGEKGKPRYDFDALTEAAGGHWHILTGCRKGHVRQALSQGGPAAAQRALADLVDRFTPSRVSIELTHHGHPLDDERNAALAGLAPRFGVGIVATTGAHFADPSRGRLAMAMAAIRARRSLDSAAGWLAPLGGAHLRSGEEMARLFAWCPEAVTAAAELGERCAFGLQLIAPRLPPFDVPDGHTEDSWLRSLVMAGARERYGPPKSAPRAYSQIEHELKVIAQLRFPGYFLVVHDITRFCRDNDILCQGRGSAANSAVCYALGVTAVDPVANELLFERFLSPARDGPPDIDIDIESDQREKVIQYVYHKYGRDYAAQVANVITYRGRSAVRDMARALGFSPGQQDAWSKQVSHWTGQADDVDGIPEQVIDLATQIRNLPRHLGIHSGGMVICDRPIADVCPVEWARMANRSVLQWDKDDCAAIGLVKFDLLGLGMLSALHYAKDLVAEHKGIEVDLARLDLSEPAVYEMLARADSVGVFQVESRAQMATLPRLKPRVFYDLVVEVALIRPGPIQGGSVHPYIRRRNGVDPVIYEHPSMAPALRKTLGVPLFQEQLMQLAVDCAGFSAAEADQLRRAMGSKRSTERMRRLRGRFYDGMRALHGAPDEVIDRIYEKLEAFANFGFPESHALSFASLVFYSAWFKLHHPAAFCAALLRAQPMGFYSPQSLVADARRHGVAVHGPCVNASLAHATCENAGTEVRLGLGAVRYLGAELAEKLVAERTANGPFTSLPDLTSRVQLSVPQVEALATAGALGCFGMSRREALWAAGAAATGRPDRLPGVGSSSHIPALPGMSELELAAADVWATGVSPDSYPTQFLRADLDAMGVLPAERLGSVSDGDRVLIAGAVTHRQRPATAQGVTFINLEDETGMVNVLCTPGVWARHRKLAHTAPALLIRGQVQNASGAITVVAERMGRLTLAVGARSRDFR", "output": "DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. Does not appear to be essential for chromosomal replication. May be involved in generating antibiotic resistance."}]}
+{"id": "function_test_940", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSRIEALPTHIKAQVLAEALPWLKQLHGKVVVVKYGGNAMTDDTLRRAFAADMAFLRNCGIHPVVVHGGGPQITAMLRRLGIEGDFKGGFRVTTPEVLDVARMVLFGQVGRELVNLINAHGPYAVGITGEDAQLFTAVRRSVTVDGVATDIGLVGDVDQVNTAAMLDLVAAGRIPVVSTLAPDADGVVHNINADTAAAAVAEALGAEKLLMLTDIDGLYTRWPDRDSLVSEIDTGTLAQLLPTLESGMVPKVEACLRAVIGGVPSAHIIDGRVTHCVLVELFTDAGTGTKVVRG", "output": "Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate."}]}
+{"id": "function_test_941", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKNILDFTLEELKEWMKENGESAFRAKQIFDWIYKKEVFNFEEMKNISKALIGKLSENFYIGIPEVIDYLSSSEDGTRKILLGLGDGNIIECVIMRYKYGNSICVSTQIGCRMGCKFCASTLEGMVRNLTAGEILSEVLIGQKLLGERISNIVLMGSGEPLDNYDNVMKFLELVNADYGLNIGQRHITLSTCGLVPKIREMADKEMQVTLAISLHAVSDEKRKTIMPIANKYSISEILDACNYYIEKTGRRITFEYSLVSGVNDTKEDAKSLGRLLKGMLCHVNLIPVNEIKENEFKKSTKKDIETFLNTLKTYGVEATVRREMGSDINAACGQLRRSYIKSKGLKL", "output": "Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs."}]}
+{"id": "function_test_942", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MYPNSPSQGRIPLPLPCEQQQPPLEQSQEQPLQPQPLQPQQASGYLSKLPVSVAPELLSPEQFIQASINLHNNVNFARMLMNANLLAVPPVSPPPWSYRDQSPLISPASPSSSFQNRKRRSDEGNIAYDVKRQKFQSPQEQTVNHQAVPLRGDLGCSYPGSPAFPLLQSPSPPVLKGHVPNSGECWLYDHVDTTLPVAKDKLSKQILELFQALQQQVCDLKKKDICRAELQREIQQIFPQSRLYLVGSSLNGFGTRSSDADLCLVLKDEPMNQHTEARHILSLLHKHFYTRLSYIERPQFIKAKVPIVKFRDKVSGAEFDLNVNNVVGIRNTFLLRTYAYIENRVRPLVLVIKMWANYHGLNDASRGTLSSYTLVLMALHYLQTLPEPIIPSLQKKYPECFDSTMQLHLVHHAPRNIPKYLSKNETPLGDLLLGFLKYFAIEFDWSKDIISVREAKALPRSDDYEWRNKFICVEEPYDRTNTARAVYERQKFDMIRAEFLRAWVALRDNRDLYSLLPWKGIMKKMNSL", "output": "Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs during oocyte maturation. Plays a central role during oocyte maturation by mediating polyadenylation of dormant mRNAs, which contain 5'AAUAAA-3' sequence in their 3'-UTR. In immature oocytes, polyadenylation of poly(A) tails is counteracted by the ribonuclease parn. During maturation parn is excluded from the ribonucleoprotein complex, allowing poly(A) elongation and activation of mRNAs. May not play a role in replication-dependent histone mRNA degradation (By similarity)."}]}
+{"id": "function_test_943", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLSVIILAAGKGTRMHSSLPKTLHTLCGEPMLFYILETAFSISNDVHLILHHQQERIKEAVLERFKGVVFHTQIVEKYSGTGGAIMQEDKTPILTKHERILILNADMPLITKDALTPLLKSHNNAIGLLHLADPKGYGRVILENHQVRKIVEEKDANDEEKAIKSVNAGVYLFERKFLEKYLPKLHNQNAQKEYYLTDLTAFGINENEKIDAIFLEEEFFLGVNCQTERAKAEEIMLERLRKNAMDLGVVMQLPKSIYLEKGVSFKGECVLEQGVRLSGTCLIENAHIKAYSVIEESQIVNSSVGPFAHARPKSTICDSHVGNFVETKNAKLQGTKAGHLSYLGDCEIGKNTNVGAGVITCNYDGKKKHQTIIGENVFIGSDSQLVAPVTIGSNVLIGSGTTITKDIPSGFLSLSRTPQTNIENGYFKFFKKS", "output": "Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain."}]}
+{"id": "function_test_944", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQSYASAMLSVFNSDDYSPAVQQNIPALRRSSSFLCTESYNSKYQRETGENSKDSVQDRVKRPMNAFFVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLTEAEKWPFFQEAQKLQAMHREKYPNYKYRPRRKANMLPKNCSLLPADPASVLCSEVQLDNRLYRDDCTKATHSRMEHQLGHLPPINAASSPQQRDRYSHWTKL", "output": "Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. Involved in different aspects of gene regulation including promoter activation or repression. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending. Also involved in pre-mRNA splicing (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity)."}]}
+{"id": "function_test_945", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MMHFLSFCLSVASLVSYAGAASTFSPARPPALPLAVKSPYLSTWLSAGTDGGNGGYLAGQWPTFWFGQVTGWAGQIRVDNSTYTWMGAIPNTPTVNQTSFEYTSTSSVFTMRVGDMVEMKVKFLSPITPDDLRRQSLVFSYLDVDVESIDGKAHDIQVYADISAEWASGDRNAIAQWDYGVTDDGVAYHKVYRQTQLLFSENTEQAEWGEWYWATDDQDGLSYQSGPDVDVRGAFAKNGKLANSDDKNYRAISTNWPVFAFSRDLGSVKTSAGTLFSIGLAQDSAIQYSGKPEGTTVMPSLWKSYFSTATAALEFFHHDYAAAAALSKDLDDRISKDSIDAAGQDYLTITSLTVRQVFAAVQLTGTPEDPYIFMKEISSNGNMNTVDVIFPAHPIFLYTNPELLKLILKPIYEIQENGKYPNTYAMHDIGTHYPNATGHPKGDDEKMPLEECGNMVIMALAYAQKAKDNDYLSQHYPILNKWTTYLVEDSIYPANQISTDDFAGSLANQTNLALKGIIGIQAMAVISNTTGHPDDASNHSSIAKDYIARWQTLGVAHDANPPHTTLSYGANETHGLLYNLYADRELGLNLVPQSVYDMQNTFYPTVKEKYGVPLDTRHVYTKADWELFTAAVASESVRDMFHQALATWINETPTNRAFTDLYDTQTGNYPAGITFIARPVMGGAFALLIL", "output": "Glutaminase catalyzes the hydrolysis of glutamine to glutamic acid and plays a key role in nitrogen metabolism. Catalyzes the hydrolysis not only of L-glutamine but also of D-glutamine."}]}
+{"id": "function_test_946", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTVTLAGNPIEVGGHFPQVGEIVENFILVGNDLADVALNDFASKRKVLNIFPSIDTGVCATSVRKFNQQAAKLSNTIVLCISADLPFAQARFCGAEGIENAKTVSTFRNHALHSQLGVDIQTGPLAGLTSRAVIVLDEQNNVLHSQLVEEIKEEPNYEAALAVLA", "output": "Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides."}]}
+{"id": "function_test_947", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNTQPHHSSPDSPQDGGWFPISIRLSGARVLLVGGGEIAVNKGRLLLDHGARIDVLAEKLHPAVQGWVENGRVRHVGERADEAVLRRLLPGCRLVYAATDSRDTNRQVAALADELNIPVCAVDDPGPSSFITPAQVRRGMVRVAVSTGGAAPVLARRLREQIETLLPEGTGRLATYMQSRRAFVSGRYPNVQDRKRIWEDFLDGPGAEAARSGDESRADARLEVLLDGERKSGEVWLVGAGPGDPDLLTLKALHLMQNADSVLYDNLVSPALLDMVRRDAELVFVGKQRDRHALPQDEINREMVRRAQGGERVLRLKGGDPFIFGRGGEEIEALVEAGVAFRLVPGISAANGCAAYSGIPLTHRDCAQACLFVTGHAKADGVLDLPWDDMADRRQTVVIYMGISTLPQLAAGLLGKGLPADWPVAIVERGTQPRQRVFTGTLSTIAQQAAEAQVKSPALVIVGQVVRHRVVSP", "output": "Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme."}]}
+{"id": "function_test_948", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTSVVADSLTETKTDSQKPIATRKDGRIDLLGLSREDIRAALKSKGLDEKQAKLRTKQLWHWMYNRGAVAFDGMTDIAKTMRPWLAEHFAISRPEVVTMQISTDGTRKWLLKTDDGYDYEMVFIPDADRGTLCISSQIGCTLNCRFCNTGTMRLVRNLTVGEIVGQIMLARDSLDEWPSKPEGRLLTNVVMMGMGEPLYNFDNVRDALKLVMDGDGIALSRRRITLSTSGVVPMMARAGEEIGVNLAVSLHAVTKVVRDEIVPINKKYGIDELLAACAAYPGVNNARRITFEYVMLKDKNDSEEDAHELVRLLQYYRLPAKVNLIPFNPWPNSPYECSTPERIARFSEIVFNAGISAPVRRTRGQDIMAACGQLKSAAERQSKRDSMITLS", "output": "Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity."}]}
+{"id": "function_test_949", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MWKLLPAAGPAGGEPYRLLTGVEYVVGRKNCAILIEKDQSISRNHAVLTANFSVTNLSQTDEIPVLALKDNSKYGTFVNEEKMQNGFSRTLKSGDSITFGVFESKFRIEYEPLVACSSCLDVSGKTALNQAILQLGGFTVNNWTEECTHLVMVSVKVTIKTICALICGRPIVKPEYFTEFLKAVQSKKQLPQIESFYPPLDEPSIGSKNVDLSGRQERKQIFKGKTFIFLNAKQHKKLSSAVVFGGGEARLITEENEEEHNFFLAPGTCVVDTGITNSQTLIPDCQKKWIQSIMDMLQRQGLRPIPEAEIGLAVIFMTTKNYCDPQGHPSTGLKTTTPGPSLSQGLSVDEKLMPSAPVNTTTYVADTESEQADTWDLSERPKEIKVSKMEQKFRMLSQDAPTVKESCKTSSNNNSMVSNTLAKMRIPNYQLSPTKLPSINKSKDRASQQQQTNSIRNYFQPSTKKRERDEENQEMSSCKSARIEMSCSLLEQTQPAIPLLWKNKEQHLSENEPVDTNSDNNLFTDTDLISTVKNSASKSHAAEKLRSNKKREMHDVTIEDEVLEQLLKDTKPELEIEVKVQKQEEDVNIRKRPRMDVETNDTFSDKAVPESSKISQENEIGKKHELKEESLWSTKEISNNDKLQDHSEMLPKKLLLTEFRSLVIKNSTSRNPSGINGDYGLLKNFKKFKKVTYPGAGKLPHIIGGSDLIAHHARKNTELEEWLRQEMEVQNQHAKEESLADDLFRYNPYLKRRR", "output": "Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11. RAD50 may be required to bind DNA ends and hold them in close proximity. NBN modulate the DNA damage signal sensing by recruiting PI3/PI4-kinase family members ATM, ATR, and probably DNA-PKcs to the DNA damage sites and activating their functions. It can also recruit MRE11 and RAD50 to the proximity of DSBs by an interaction with the histone H2AX. NBN also functions in telomere length maintenance by generating the 3' overhang which serves as a primer for telomerase dependent telomere elongation. NBN is a major player in the control of intra-S-phase checkpoint and there is some evidence that NBN is involved in G1 and G2 checkpoints. The roles of NBS1/MRN encompass DNA damage sensor, signal transducer, and effector, which enable cells to maintain DNA integrity and genomic stability. Forms a complex with RBBP8 to link DNA double-strand break sensing to resection. Enhances AKT1 phosphorylation possibly by association with the mTORC2 complex (By similarity)."}]}
+{"id": "function_test_950", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEEEQLRYSRRLRHTLRRRYEDDGISDDEIEGKRTFDLEEKLRSSKYNSNFITYMEGKDFNMKFIQEGGLRDPIIFTKSEGLGIKMPDPNFSVNDVKMFVGSRRVVDVMDVGTQKGIEMTMAQWAKYYETPEEEREKLYNVISLEFSHTKLENLVQRPTTVDQIDWVDNIWPRHLKDRQTESTNVIQEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHILRGGKVFWLIPPTDQNLELYENWLLSGKQGDVFLGDRVTECQRIELKQGYTFVIPSGWIHAVYTPQDTLVFGGNFLHSFNIPMQLRIYSIEDRTRVPTKFRYPFYYEMCWYVLERYVYCMMRRSHLTKEFQRESLSIDLELNGRQRPDTPSSSSSSSSSGLSSSSDNDDSSDQDWEEEEGLRKRERDRCRVERELQRKRNRDRQQRDQERDRHGRTERIIIHTLPASLRPLTPPPSLPLPTPDSPPSTSPFLTWFEVEGLRCLVLKLESLPPLKKCLPDGIHDPEALIFDIKRLLEDHAHDPPELALTGVPIIQWPKRSQYKVHLRPKIQFTKPHTMRPASRHSTAPPRTSGTPSGTTASSGARRRRVRCRKCQACVQRECGTCHYCKDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCALCGEVDQTNDTQDFERKLMECSVCNEIVHPGCLEMDGEGLLSDELPNYWECPKCYEGQKHTVEANHDRILLHSKRKAADNYESSHYYPAKVLRPPLGQSPPSPPLLLLPPSPSSAPPTPPSAQTQVPLASREERAKRRQLAREKENHPTGCDQSEGDRLRLRGPYLTVTLQRPPKELSSTSIVPKLQAITPNPRQPIRAAPLHQDEEREEEEEEEEEEEETENVMLGQRKDSTSMQKDVWLSVFHYLTHEELCICMRVCKAWYKWGCDKRLWSRIDVSRCKSLVPQALSGIIKRQPIYLDLSWTNVSKKQLIWLINRLPGLKDLILAGCTWSAVSALASCSCPLLRTLDLRWTVGIKDTQIRDLLTPASDKSGHDSRSKLRLLTDLRLSGLDISDVTLRLIIRHCPLLSKLDLSHCPLLSDQSVNLLTAVGSSTRGTLTHIHLAGCKGVTDESLLYLRRATNLSLIDLHGCKQVTRGACEEFISDLSVSTLYCLSDDKLIQRIS", "output": "Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis (By similarity). May play a role in the regulation of circadian gene expression (By similarity)."}]}
+{"id": "function_test_951", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEVSRPYVNTVDVIDFGIDKRFFRLPVSGILAQEGITPNGPQIAIINALEDPRHRFVTACVSRRVGKSFIAYTLGFLKLLEPNVKVLVVAPNYSLANIGWSQIRGLIKKYGLQTERENAKDKEIELANGSLFKLASAAQADSAVGRSYDFIIFDEAAISDVGGDAFRVQLRPTLDKPNSKALFISTPRGGNWFKEFYAYGFDDTLPNWVSIHGTYRDNPRADLNDIEEARRTVSKNYFRQEYEADFSVFEGQIFDTFNAIDHVKDLKGMRHFFKDDEAFETLLGIDVGYRDPTAVLTIKYHYDTDTYYVLEEYQQAEKTTAQHAAYIQHCIDRYKVDRIFVDSAAAQFRQDLAYEHEIASAPAKKSVLDGLACLQALFQQGKIIVDASCSSLIHALQNYKWDFQEGEEKLSREKPRHDANSHLCDALRYGIYSISRGK", "output": "The terminase large subunit acts as an ATP driven molecular motor necessary for viral DNA translocation into empty capsids and as an endonuclease that cuts the viral genome to initiate and to end a packaging reaction The terminase lies at a unique vertex of the procapsid and is composed of two subunits, a small terminase subunit involved in viral DNA recognition (packaging sequence), and a large terminase subunit possessing endonucleolytic and ATPase activities. Both terminase subunits heterooligomerize and are docked on the portal protein to form the packaging machine. The terminase large subunit exhibits endonuclease activity and cleaves the viral genome concatemer. Once the capsid is packaged with the DNA, the terminase complex is substituted by the tail."}]}
+{"id": "function_test_952", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRECISIHIGQAGIQVGNACWELYCLEHGIQPDGQMPSDKTVGGGDDAFNTFFSETGAGKHVPRAVFVDLEPTVIDEVRTGAYRQLFHPEQLISGKEDAANNFARGHYTIGKEIVDLCLDRIRKLADNCTGLQGFLVFNAVGGGTGSGLGSLLLERLSVDYGKKSKLGFTVYPSPQVSTSVVEPYNSVLSTHSLLEHTDVAVLLDNEAIYDICRRSLDIERPTYTNLNRLVSQVISSLTASLRFDGALNVDVTEFQTNLVPYPRIHFMLSSYAPVISAEKAYHEQLSVAEITNSAFEPSSMMAKCDPRHGKYMACCLMYRGDVVPKDVNAAVATIKTKRTIQFVDWCPTGFKCGINYQPPTVVPGGDLAKVQRAVCMISNSTSVAEVFSRIDHKFDLMYTKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGAESGEGDEGDEEEY", "output": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin."}]}
+{"id": "function_test_953", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSTADRYRKVFPVTWEQLHRDAKALSWRLLEKGPYKGIIAIARGGLVPAAVIARELDIHLVETICISSYQWQEQTSSHKVLKTVEGRGEGWLIIDDLADTGGTARLVREMLPEAHFATVYAKPAGRPLVDTFITEVSQDTWILFPWDSEVQYVVPLVNQPQQS", "output": "Purine salvage pathway enzyme that catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of the 6-oxopurines guanine and xanthine to form the corresponding ribonucleotides GMP (guanosine 5'-monophosphate) and XMP (xanthosine 5'-monophosphate), with the release of PPi. To a lesser extent, also acts on hypoxanthine."}]}
+{"id": "function_test_954", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSSKASKAPASKAPAEKKPAAKKTSSSVDASKKRTKTRKETYSSYIYKVLKQTHPDTGISQKSMSILNSFVNDIFERIASEASKLAAYNKKSTISAREIQTAVRLILPGELAKHAVSEGTRAVTKYSSSTQA", "output": "Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling."}]}
+{"id": "function_test_955", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTPLIFVTGGVVSSLGKGIAAASLASILEARGLKVTMMKLDPYINVDPGTMSPFQHGEVYVTDDGAETDLDLGHYERYVRTRLSRKNSVTTGRIYENVIRKERRGDYLGATVQVIPHITDEIRRCIDEATAGFDVALIEIGGTVGDIESLPFLEAIRQVRTERGAEKAMFMHLTLVPYIAAAGELKTKPTQHSVKELRSIGIQPDVLLCRSEQAVPDSERRKIALFTNVSERAVISCPDIDVLYGMPLELLRQGLDELVIDQFKLRDKVAAADLSEWAAVVDAVKHPLDEVNIAVVGKYVDHQDAYKSVAEALRHGGLRQRTKVNLKWLEAQDLEGSDMSALQDIDGILVPGGFGDRGFEGKVQTSKFAREQKVPYFGICYGMQAAVVDYARHVADLDAANSTENDRQSPHPVIGLITEWRTATGEVEKRDEKSDLGGTMRLGLQEQRLKPGTLAREVYGKDVVAERHRHRYEFNNRYRTQLEDAGLVISGKSMDDTLVEVVELPRDTHPWFLACQAHPEFLSTPRDGHPLFIGFVRAAREKKAGGKLLKEARA", "output": "Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates."}]}
+{"id": "function_test_956", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSSGANITYASRKRRKPVQKTVKPIPAEGIKSNPSKRHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVALKSTPADRNGGQDQCRAQIRDWQDLQEGEFLLQALNGFVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELIHTEDRAEFQRQLHWALNPSQCTDSAQGVDEAHGPPQTAVYYTPDQLPPENASFMERCFRCRLRCLLDNSSGFLAMNFQGRLKYLHGQNKKGKDGALLPPQLALFAIATPLQPPSILEIRTKNFIFRTKHKLDFTPSGCDAKGQLILGYTEVELCTRGSGYQFIHAADMLHCAESHIRMIKTGESGMTVFRLLAKHSRWRWVQSNARLIYRNGRPDYIIATQRPLTDEEGREHLQKRSMSLPFMFATGEAVLYEISSPFSPIMDPLPIRAKSNTSRKDWAPQSTPSKDSFHPSSLMSALIQQDESIYLCPPSSPAPLDSHFLMGSVSKCGSWQDSFAAAGSEAALKHEQIGHAQDVNLALSGGPSELFPDNKNNDLYSIMRNLGIDFEDIRSMQNEEFFRTDSTATGEVDFKDIDITDEILTYVQDSLNNSTLLNSACQQQPVTQHLSCMLQERLQLEQQQQQQLQQPPTQALEPQQQLCQMECPQQDLGQRHTQINGSFASWNPTPPVSFNCPQQELKHYHLFSSLQGTAQEFPYKPEVDGMPYTQNFAPCNQPLLPEHSKSVQLDFPGRDFEPSLHPTTSNLDFVSCLQVPENQSHGINSQSAMVSPQTYYAGAMSMYQCQPGPQHTPVDQTQYSSEIPGSQAFLSKVQSRGVFNETYPSDLSSIGHAAQTTGHLHHLAEARPLPDITPGGFL", "output": "Ligand-activated transcription factor that enables cells to adapt to changing conditions by sensing compounds from the environment, diet, microbiome and cellular metabolism, and which plays important roles in development, immunity and cancer. Upon ligand binding, translocates into the nucleus, where it heterodimerizes with ARNT and induces transcription by binding to xenobiotic response elements (XRE). Regulates a variety of biological processes, including angiogenesis, hematopoiesis, drug and lipid metabolism, cell motility and immune modulation. Xenobiotics can act as ligands: upon xenobiotic-binding, activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Next to xenobiotics, natural ligands derived from plants, microbiota, and endogenous metabolism are potent AHR agonists. Tryptophan (Trp) derivatives constitute an important class of endogenous AHR ligands. Acts as a negative regulator of anti-tumor immunity: indoles and kynurenic acid generated by Trp catabolism act as ligand and activate AHR, thereby promoting AHR-driven cancer cell motility and suppressing adaptive immunity. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-BMAL1 heterodimer mediated transcriptional activation of PER1. The heterodimer ARNT:AHR binds to core DNA sequence 5'-TGCGTG-3' within the dioxin response element (DRE) of target gene promoters and activates their transcription."}]}
+{"id": "function_test_957", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLTIQFLCPLPNGLHARPAWELKEQCSQWQSEITFINHRQNAKADAKSSLALIGTGTLFNDSCSLNISGSDEEQARRVLEEYIQVRFIDSDSVQPTQAELTAHPLPRSLSRLNPDLLYGNVLASGVGVGTLTLLQSDSLDSYRAIPASAQDSTRLEHSLATLAEQLNQQLRERDGESKTILSAHLSLIQDDEFAGNIRRLMTEQHQGLGAAIIRNMEQVCAKLSASASDYLRERVSDIRDISEQLLHITWPELKPRNNLVLEKPTILVAEDLTPSQFLSLDLKNLAGMILEKTGRTSHTLILARASAIPVLSGLPLDAIARYAGQPAVLDAQCGVLAINPNDAVSGYYQVAQTLADKRQKQQAQAAAQLAYSRDNKRIDIAANIGTALEAPGAFANGAEGVGLFRTEMLYMDRDSEPDEQEQFEAYQQVLLAAGDKPIIFRTMDIGGDKSIPYLNIPQEENPFLGYRAVRIYPEFAGLFRTQLRAILRAASFGNAQLMIPMVHGLDQILWVKGEIQKAIVELKRDGLRHAETITLGIMVEVPSVCYIIDHFCDEVDFFSIGSNDMTQYLYAVDRNNPRVSPLYNPITPSFLRMLQQIVTTAHQRGKWVGICGELGGESRYLPLLLGLGLDELSMSSPRIPAVKSQLRQLDSEACRELARQACECRSAQEIEALLTAFTPEEDVRPLLALENIFVDQAFSNKEQAIQFLCGNLGVNGRTEHPFELEEDVWQREEIVTTGVGFGVAIPHTKSQWIRHSSISIARLAKPVDWQSEMGEVELVIMLTLGANEGMNHVKVFSQLARKLVNKNFRQSLFAAQDAQSILTLLETELTF", "output": "Multifunctional protein that includes general (non sugar-specific) and sugar-specific components of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FryABC PTS system is involved in fructose transport."}]}
+{"id": "function_test_958", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIKKNNLLTKKKPIANKSNKYAIRKFTVGTASIVIGAALLFGLGHNEAKAEENTVQDVKDSNMDDELSDSNDQSSNEEKNDVINNSQSINTDDDNQIKKEETNSNDAIENRSKDITQSTTNVDENEATFLQKTPQDNTQLKEEVVKEPSSVESSNSSMDTAQQPSHTTINSEASIQTSDNEENSRVSDFANSKIIESNTESNKEENTIEQPNKVREDSITSQPSSYKNIDEKISNQDELLNLPINEYENKVRPLSTTSAQPSSKRVTVNQLAAEQGSNVNHLIKVTDQSITEGYDDSDGIIKAHDAENLIYDVTFEVDDKVKSGDTMTVNIDKNTVPSDLTDSFAIPKIKDNSGEIIATGTYDNTNKQITYTFTDYVDKYENIKAHLKLTSYIDKSKVPNNNTKLDVEYKTALSSVNKTITVEYQKPNENRTANLQSMFTNIDTKNHTVEQTIYINPLRYSAKETNVNISGNGDEGSTIIDDSTIIKVYKVGDNQNLPDSNRIYDYSEYEDVTNDDYAQLGNNNDVNINFGNIDSPYIIKVISKYDPNKDDYTTIQQTVTMQTTINEYTGEFRTASYDNTIAFSTSSGQGQGDLPPEKTYKIGDYVWEDVDKDGIQNTNDNEKPLSNVLVTLTYPDGTSKSVRTDEEGKYQFDGLKNGLTYKITFETPEGYTPTLKHSGTNPALDSEGNSVWVTINGQDDMTIDSGFYQTPKYSLGNYVWYDTNKDGIQGDDEKGISGVKVTLKDENGNIISTTTTDENGKYQFDNLNSGNYIVHFDKPSGMTQTTTDSGDDDEQDADGEEVHVTITDHDDFSIDNGYYDDDSDSDSDSDSDSDDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSGLDNSSDKNTKDKLPDTGANEDHDSKGTLLGALFAGLGALLLGKRRKNRKNKN", "output": "Binds to the N-terminus of the B beta-chain of human fibrinogen and thereby interferes with thrombin cleavage and release of fibrinopeptide B, thus interfering with fibrin clot formation. This may hinder host defense against microbial infections."}]}
+{"id": "function_test_959", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKTLLLTLVVVTIVCLDLGYTMQCKTCSFYTCPNSETCPDGKNICVKRSWTAVRGDGPKREIRRECAATCPPSKLGLTVFCCTTDNCNH", "output": "Exhibits M2 muscarinic acetylcholine receptor (CHRM2)-blocking activity, but has a weak binding activity toward nicotinic AChR. Moreover, it inhibits collagen-induced platelet aggregation."}]}
+{"id": "function_test_960", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSLYRSVVWFAKGLREYTKSGYESACKDFVPHDLEVQIPGRVFLVTGGNSGIGKATALEIAKRGGTVHLVCRDQAPAEDARGEIIRESGNQNIFLHIVDLSDPKQIWKFVENFKQEHKLHVLINNAGCMVNKRELTEDGLEKNFAANTLGVYILTTGLIPVLEKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQVVLTERWAQGHPAIHFSSMHPGWADTPGVRQAMPGFHARFGDRLRSEAQGADTMLWLALSSAAAAQPSGRFFQDRKPVSTHLPLATASSSPAEEEKLIEILEQLAQTFK", "output": "Putative oxidoreductase."}]}
+{"id": "function_test_961", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRPRLWLLLAAQLTVLHGNSVLQQTPAYIKVQTNKMVMLSCEAKISLSNMCIYWLRQRQAPSSDSHHEFLTLWDSAKGTIHGEEVEQEKIAVFRDASRFILNLTSVKPEDSGIYFCMIVGSPELTFGKGTQLSVVDFLPTTAQPTKKSTLKKRVCRLPRPETQKGPLCSPVTLGLLVAGVLVLLVSLGVAMHLCCRRRRARLRFMKQFYK", "output": "Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing (By similarity)."}]}
+{"id": "function_test_962", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLKMSGWQRQSQNQSWNLRRECSRRKCIFIHHHT", "output": "[Isoform AltDDIT3]: Product of the upstream open reading frame (uORF) of DDIT3/CHOP that is specifically produced in absence of stress, thereby preventing translation of downstream stress effector DDIT3/CHOP."}]}
+{"id": "function_test_963", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDMRVPAQLLGLLLLWLPGARCAIWMTQSPSLLSASTGDRVTISCRMSQGISSYLAWYQQKPGKAPELLIYAASTLQSGVPSRFSGSGSGTDFTLTISCLQSEDFATYYCQQYYSFP", "output": "V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens . The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen ."}]}
+{"id": "function_test_964", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGLEDEQKMLTESGDPEEEEEEEEELVDPLTTVREQCEQLEKCVKARERLELYDEHVSSRSHTEEDCTEELFDFLHAKDHCVAHKLFNNLK", "output": "May be a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1."}]}
+{"id": "function_test_965", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MHYIKTWSLLGEMSEKLRRCRKELTAAIDRAFEGVSYSQECTGQQRLELSAAPLSFSLPVHRLLCRRHPLAACSSAAPFAAVPCAPENENPAFATNHAPVNAKPHALCPERKPLTSKENVLMHSSILAPERESWRTAGEGENWRKENLRKDMERDLKADSNMPLNNSSQEVTKDLLDMIDHTSIRTIEELAGKIEFENELNHMCGHCQDSPFKEEAWALLMDKSPQKATDADPGSLKQAFDDHNIVETVLDLEEDYNVMTSFKYQIE", "output": "Essential for normal spermatogenesis and male fertility."}]}
+{"id": "function_test_966", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEEGVQAPDWDSDETVIEGSVTESDLEEKELPWRRLLFDQDASLKSEFSLHPDTRGMCKGMPSPEIQLGFKLREDLQEQMNKNKMMPVLSEDTILQSQDETERNQALLQTRKNCSMFIGSFRQSGLSLNHQNIEGPEAESPEVLPHIEKELSEGRDSPEVSLLSGTAITVSDTVAVKETSLVEPEKILAAPNTFFEPRKEVTMTMTSEETKDEESSLETFVSALESLLTSPESTQEERLFELVSDFDRKELMNPLSDSLSSISIPLNSWSACHRDLLEDAKDDALPAELLEALNTLSEAKVETICHRKEGGSSLIARNECLEVEFNTSQTNEDCTQIAETLQDPNPSGLQTLAHQNITSCEPLSNKRNSNSVTNSSDQETACVLRRSSRLEKLKVSRDAKYSDHMYKMPEKILPKILGCEDLTNNNSSAQNFRMQDPALMIDGKEKNMHSARFKNGKQIRKNEQFSGKKEKMKVNKISLHSINRRNIFGENLVYKAALHDDADLVHHCIKKGGNVNQPSYAGWTALHEASVGGFYRTASELLKGGADVNIKGLYQITPLHDAVMNGHYKVAELLLLNGADPLFRNDDGKCALDEAKDLCMKRLLERYIPKHQKCLTSAQRSSIDPLDIEDVYQHKKPKFSSKSHIWHVYNENSNRQKLEHVKVNKGSKASLFINKEDVYEYYQKDPKNTKFGKSKHKQSTLDQIYSTGLRKGNLHNVKDPNTNVPKGIGRRKTQHKRTQVDDVDCNPRKILAVSPSRRINRLVTYQQHIPETHNDLPEELCEPSSLTLSSLRNGLDSSTEACSVSKEKHIQNLDLSDSQEVQCLELESVDQTEAVSFPGLLLHKEIKLPVVTTDKQPHTLQEQHHVLYKSHENSNLVPKDERFNKWENSFLSFVKENSDNDDDDDCSTSEKAITSKKVLCSTGGKKHYNFKENLTNKKEMGFQQFLLSEDHLSQENELKAVSLTTLPEQEAVNFSYSDNAVISEHVANYEQCIFGPSFDHSNGNPEQNSLACMRTLLTHEASKLTNHVELFKKPQDYIPRAPTFLMNQTDTHIVEKMAKNCDTERNYIDRDQKIIYSNEPLSIVAHSQVIETTKVEKRRQNHLESETIHNIDSHSTDNMSKELANISKLSQREKKEISHKPGMKAGRINKRNARGESQLHLAVRRGNLPLVKALIESGADVNLNDNAGWTPLHEASNEGSIDIIVELLKAGAKVNCENIDGILPLHDAVANNHLKAAEILLQNGANPNQKDQKQKSALDEADDEKMKELLRSYGAIETVNRDESDAIVNEKIPAVRSKRHKQCFCDDGKTIDSSSLSHQERSRESLSVHQTLSAILQDIEEKQEYLLEFEIRNPEDAEQYIEKMLKIKKIMDNVLAKQKAERDDLAKKYRVSIESFKHGALREQLANLAARQKSLLVVAKKQKKISLKIQNCRNVTSLPCLSLRKLPPRSEISSEKDSQELTSLENLEHPQSGSLSPVSGSMQETQLSLETWNYSQNTNICLNSEAVRRGEFSGNDMNSKQNGSDCTLDGFPKSRHSDGTEKNKLPSQPVAFIGQTEYSQKENDLTEATDKDHEFYVSSPVIGKLNISETASVLAENAAHPSNIICDQDLSNYDPKRGNRKTSSQQSPTGASESLAHQGIAVLGSDTVHQMKPYLKKSVSVVPCADDSQISSSSGSGQQDTIKKALNYSTAPKKKCIQIKDLILLGRINPGNNILEFKTQETTHKASILLNGKLKVESGQIYKNPVTWLKDLLGGNSYVTWNYAWSKVTYLGKELLRYVSEDAPILPEPNSVPQQYQPCLPEVACLDDPVQEPNKSMFEKTKFGQGTSRESMQSSPRYLQINEILLISDQEFLPCHIMDQHWKFCVECEELTP", "output": "Required for DNA double-strand breaks (DSBs) formation during meiotic recombination. Regulates the spatial and temporal patterns of pre-DSB recombinosome assembly and recombination activity by acting as a scaffold that anchors REC114 and other factors to specific genomic locations, thereby regulating DSB formation. Plays a key role in recombination in the pseudoautosomal regions of sex chromosomes."}]}
+{"id": "function_test_967", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEFGLSWVFLVAILKGVQCEVQLVESGGGLVQPGRSLRLSCTASGFTFGDYAMSWVRQAPGKGLEWVGFIRSKAYGGTTEYAASVKGRFTISRDDSKSIAYLQMNSLKTEDTAVYYCTR", "output": "V region of the variable domain of immunoglobulin heavy chains that participates in the antigen recognition . Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens . The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen ."}]}
+{"id": "function_test_968", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGDNITSITEFLLLGFPVGPRIQMLLFGLFSLFYVFTLLGNGTILGLISLDSRLHAPMYFFLSHLAVVDIAYACNTVPRMLVNLLHPAKPISFAGRMMQTFLFSTFAVTECLLLVVMSYDLYVAICHPLRYLAIMTWRVCITLAVTSWTTGVLLSLIHLVLLLPLPFCRPQKIYHFFCEILAVLKLACADTHINENMVLAGAISGLVGPLSTIVVSYMCILCAILQIQSREVQRKAFCTCFSHLCVIGLFYGTAIIMYVGPRYGNPKEQKKYLLLFHSLFNPMLNPLICSLRNSEVKNTLKRVLGVERAL", "output": "Odorant receptor."}]}
+{"id": "function_test_969", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLASSKRMNSSSRSQILLRWKSDKAQSGPYNVEKEILTSRFLRDTETCRQNFRNFPYPDLAGPRKALSQLRELCLKWLRPEIHSKEQILELLVLEQFLTILPGEVRTWVKSQYPESSEEAVTLVEDLTQILEEEAPQNSTLSQDTPEEDPRGKHAFQTGWLNDLVTKESMTFKDVAVDITQEDWELMRPVQKELYKTVTLQNYWNMVSLGLTVYRPTVIPILEEPWMVIKEILEGPSPEWETKAQACTPVEDMSKLTKEETHTIKLEDSYDYDDRLERRGKGGFWKIHTDERGFSLKSVLSQEYDPTEECLSKYDIYRNNFEKHSNLIVQFDTQLDNKTSVYNEGRATFNHVSYGIVHRKILPGEKPYKCNVCGKKFRKYPSLLKHQSTHAKEKSYECEECGKEFRHISSLIAHQRMHTGEKPYECHQCGKAFSQRAHLTIHQRIHTGEKPYKCDDCGKDFSQRAHLTIHQRTHTGEKPYKCLECGKTFSHSSSLINHQRVHTGEKPYICNECGKTFSQSTHLLQHQKIHTGKKPYKCNECWKVFSQSTYLIRHQRIHSGEKCYKCNECGKAFAHSSTLIQHQTTHTGEKSYICNICGKAFSQSANLTQHHRTHTGEKPYKCSVCGKAFSQSVHLTQHQRIHNGEKPFKCNICGKAYRQGANLTQHQRIHTGEKPYKCNECGKAFIYSSSLNQHQRTHTGERPYKCNECDKDFSQRTCLIQHQRIHTGEKPYACRICGKTFTQSTNLIQHQRVHTGAKHRN", "output": "May be involved in transcriptional regulation."}]}
+{"id": "function_test_970", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAPQRSQDKTPIQLLHEYGIKISSAPKYELIHADGDAHQPSFMFSVTIGEVTCKGRGSTKKAAKHEAAEAALKLLKRDSQIIDQRDNNGLSPEAGEASNPVGILQELAMQRVWCLPEYVVFMETGPGHMKEFTIACRLEGLEETGSGSSKKLARRAAAENMIAKLQSLSGSSEITWSPPSRVYVESLRNSTGEKVSLLKRTPLSLPNTDYIQMLLEISLELGFQVTYIDIDELTVNGQYQCLVELSTRPVTVCHGSGVTSSNAHNAAAHNALQYIKMVASKH", "output": "Activates eif2ak2/pkr in the absence of double-stranded RNA (dsRNA), leading to phosphorylation of eif2s1/efi2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by dicer1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Does not seem to be required for processing of pre-miRNA to miRNA by dicer1 (By similarity)."}]}
+{"id": "function_test_971", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MFSTTMGFPSTPLEAKQALGISSGISSVSSGLRSGSPMLSASYEPQLSFARCVEQWKGKEIARWIEGLGDQMNPYLGMIRDNIKSGKQLEALDDDSLKKIGISALGARKTIFQAVSLLLYFCHESEHENLQRLAQQVKTSCLYVERTMTSAMRMREKAIRRSEIVNILNSVSNAVLQLAEHTKRFVFWLDRTPFDEEPEFINVRNSVSSFMWNLLRNVNVQPKALFETGSQIVRMSKELAYECQKIVDCDDPLILYACFIESALLRRRSDNINWGLNIQSSYRGVHVISEIKEGSPADACTKIDAGDEILMINGRTVVGWDLTSVVQQVGALDVLELSLIVKRRPREPQLPKQSKLAARALAPSSQTAKTYSTDDYDPFGQSEPLKRHRSCHVISEIIKENERKIRISRRLIRRSSIASACPRKERKNIDERALDGDDEDDWDVHEFIRNVDGEEEALVPRIAKRTRTMRHQPDGYVRSFIDNKLVTDIEDDVVNDQLTFNVKCPNEFAQIKEVDKEELKVLNLPEARVSDEDWKAPYQEFAAPSFRAVGDSNISGFSLDSPRLLPVSSRMTSSVEESAFGVLPSPSTSSMNSVSSPAPFGKFQMSTSQTEWSPNPDDLPGSPISAAYAGMEKLFEGWVRRRKTRAELNANELTNKWPKIWMCLRGHYLLLYTNQNTKRPEMVINLIKATISDSTDLKTSKKNIFRITAAPLDYHFSCFTALDWRNWTQKMKMAKEIFANAGTQPRIMSQSVSSYNNDLSDQNFFLGQQTGSGLSTLPRVTTNGMTTSKSGGLGGGGFKQK", "output": "Non-essential component of the Ras signaling pathway."}]}
+{"id": "function_test_972", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MMGPEDAGACSGRNAELLPVPGPMGQDGKTVPATGGFSGGAVAAEPPGEAGEEEAPPPRQLLQRYLAAAAGPLQPGLGGVEAEAAAVPAARGSGMTNGDSGFLLLQDRRGPEEARRRRTCGRPCLAEPADEGVDGAGGLDDWAAPLEDPLRSCCLAAGDTDDPDPTATTSAGRDVGSAESSLGLPDARFGSRNTFEVSRRQSAGDLLPSAGQSAPLPAAEQGPGGTTVRARRSGGFADFFARNLFPKRTKELKSVVHSAPGWKLFGKVPPRENLQKTSKIIQQEYEARTGRTCKVPPQSSRRKNFEFEPLSTTALILEDRPSNLPAKSVEEALRHRQEYDEMVAEAKKREIKEAHKRKRIMKERFKQEESIASAMVIWINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRAKERWKSFSESSSDSDMEGLSVADREASLELIKLDISRTFPSLYIFQKGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNRPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSYNLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILLQMDFIHIAQFLTKLPEDITSEKLFSCIAAIQMQNSTKKWTQVFASVTKDIKEGDKNNSPALKS", "output": "RAB11A-binding protein that plays a role in neurite outgrowth."}]}
+{"id": "function_test_973", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKTKELVIMALFAAIGAALHSIIPPFLGGMKPDMMLIMMFMGILLFPRVQNVLVIGIVTGIISALTTAFPAGQIPNIIDKPVSAFLFFSLFLLFRKSRKTGAAAVLTVIGTILSGIVFLSSALLIVGLPGGFAALFAAVVLPAAVLNTISMIIIYPIVQTILRRSSFMEAAK", "output": "Probably involved in tryptophan uptake."}]}
+{"id": "function_test_974", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDEEYEVIVLGTGLKECILSGLLSVDGVKVLHMDRNDYYGGESTSLNLNQLWKKFRGEEKAPEHLGASRDYNVDMMPKFMMGNGKLVRTLIHTDVTKYLSFKAVDGSYVFVKGKVQKVPATPMEALKSSLMGIFEKRRAGKFFSFVQEYDEKDPKTHDGMDLTRVTTKELIAKYGLDGNTIDFIGHAVALHTNDQHLDQPAFDTVMRMKLYAESLARFQGTSPYIYPLYGLGELPQAFARLSAVYGGTYMLNKPECKVEFDEGGKVIGVTSEGETAKCKKIVCDPSYLPNKVRKIGRVARAIAIMSHPIPNTNDSHSVQVIIPQKQLARKSDMYVFCCSYSHNVAPKGKFIAFVSTDAETDNPQTELKPGTDLLGPVDEIFFDMYDRYEPVNEPELDNCFISTSYDATTHFETTVADVLNMYTLITGKQLDLSVDLSAASAAEE", "output": "Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP."}]}
+{"id": "function_test_975", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MATSSSVVSSVPQQHQVFLNFRGDELRNNFVSHLDKALRGKQINVFIDEAVEKGENLDNLFKEIEKSRIALAIISQKYTESKWCLNELVKMKELEGKLVTIPIFYNVEPATVRYQKEAFGAALTKTQENDSDGQMKKWKEALTYVSLLVGFPFNSKSKEKETTLIDKIVDAVLQKLSKISSEESTSGSVDQGRGEEVEEAKADKISGLNQRLKELEEKVAITGDKRDETRIVEVVGMPGIGKSTLLKAFYETWKTRFLSSALLQNISELVKAMGLGRLTGMLLKELLPDENIDEETYEPYKEKLLKNTVFIVLDGISDETHIQKLLKDHRKWAKKGSKIVIARRAVTRDLLHEDSMVRYTYFVPLLSHRDGLNHFCHYAFRHFAAHQNNKEAFMKESKEFVRYARGHPLILKLLGEELREKSLSYWEEKLKSLPKSLSQNIRDRVLQVTYDELSQVQKDAFLDIACFRSHDLVYVKSLLDSSGPAFSKATVTIDALKDMFMIYISDSRVEMHDLLYTFAMELGPEARDDDGRGRHRIWHHHNQDNKGRLNRLLKRPGGSTSVRSFFLDMYVMKTDVTLGTDYLKNMRNLRYLKFYSSHCPQECTPKENIHIPGELELPLEEVRCLHWLNFPKDELPQDFIPKNLVDLKLPYSKIRQIWREEKDAPKLRWVDLNHSSKLENLSGLSQALNLERLNLEGCTALKTLLLGPENMASLVFLNLKGCTGLESLPKINLRSLKTLILSNCSNLEEFWVISETLYTLYLDGTAIKTLPQDMVKLTSLVKLYMKDCEMLVKLPEEFDKLKVLQELVCSGCKRLSSLPDVMKNMQCLQILLLDGTAITKIPHISSLERLCLSRNEKISCLSNDIRLLSQLKWLDLKYCTKLVSIPELPTNLQCLDANGCESLTTVANPLATHLPTEQIHSTFIFTNCDKLDRTAKEVITTYAQRKCQMLSDALKRWNEGFVPEALFSTCFPGCEVPSWFCHEAVGSVLKLNLLPHWNENRFVGIALCAVVGSLPNCQEQTNSCSVTCTFNIASKDSKKGDPYKISFDRLVGRWNKHGNKLDKKGNKLKKTESDHVFICYTRCSNSIKCLQDQHSGTCTPTEAFLEFGVTDKESRLEVLKCGLRLVYASDEPQKTNSDMDLSLSSSDSTPTRNGSSNTTTSSGSVSTNTIREEDSNILHEAQSQNGRGL", "output": "Probable disease resistance protein."}]}
+{"id": "function_test_976", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MMAGRRSWPAMATVLLALLVCLGELVDSKPQPSDEKASPDKHHRFSLSRYAKLANRLANPKLLETFLSKWIGDRGNRSVK", "output": "Inhibits calcium transport into spermatozoa; it does not bind directly to calcium. Binds to calmodulin. Inhibits the growth of microorganisms. Seem to act as an antibiotic by permeabilizing the bacterial membrane."}]}
+{"id": "function_test_977", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNRLQLLSKGLRLIHKMSEEALAGVPLVHISPEGIFKYVMINVFDGGDASKAVIRGFADCTWHADIFEREEEVFKKLGLRAECPGGGRIEHNPEKKYLKVYGYSQGFGKADHAQTKRILATKYPDYTIEISDEGY", "output": "JanA and janB regulate somatic sex differentiation."}]}
+{"id": "function_test_978", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSLLQFSGLFVVWLLCTLFIATLTWFEFRRVRFNFNVFFSLLFLLTFFFGFPLTSVLVFRFDVGVAPPEILLQALLSAGCFYAVYYVTYKTRLRKRVADVPRRPLFTMNRVETNLTWVILMGIALVSVGIFFMHNGFLLFRLNSYSQIFSSEVSGVALKRFFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIGIIRGWISLWMLAAAGVLGIVGMFWLALKRYGMNVSGDEAFYTFLYLTRDTFSPWENLALLLQNYDNIDFQGLAPIVRDFYVFIPSWLWPGRPSMVLNSANYFTWEVLNNHSGLAISPTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNREPNRYKAAILHSFCFGAIFNMIVLAREGLDSFVSRVVFFIVVFGACLMIAKLLYWLFESAGLIHKRTKSSLRTQVEG", "output": "Probably involved in the polymerization of enterobacterial common antigen (ECA) trisaccharide repeat units. Required for the assembly of the phosphoglyceride-linked form of ECA (ECA(PG)) and the water-soluble cyclic form of ECA (ECA(CYC))."}]}
+{"id": "function_test_979", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIETAIYGKTVDDQSRCVHWHLPKDVIAIRFKCCDKYYACFECHQELSSHPLEKYDLLDDANKHLIICGVCRHEMTFAEYYDYNSNLICPNCRSPFNPGCKLHYHLYFQNPPPAMC", "output": "Required for the assembly or recycling of the small Tim proteins in the mitochondrial intermembrane, thereby participating in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. Probably acts by facilitating the formation of disulfide bonds in small Tim proteins."}]}
+{"id": "function_test_980", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSGEQKSYLENQLEAVAEKTDAGYTFTFQREKIKLLDGLEANVIKDINPFFHKEIDVTDDEVIITIQPPSSYKAFRFMKAKDKKSKWQFAYQLVQAVQQHNLSRLNLIVAPENIVFDKGLTPYFLHYGVKESIPPYERDEERVWQELKAAAALAVDGAFAFEDYLKFNETLTFSAEAKAILDAESYDDLLELIQTHIDELEAKAKTYIHIPRKKWNIQRYIGLGLIVLLVPALIYSMYALFFAQPKHQAIVDSNRAFLNKQYSEVISTLSKYDAESLPESVQYQLATSYVEVENLGSAKTKNIENNLVTLQSDPQHFLYWIDYGRGEYKEAISIGRKLEYNDYIYFALAKYKQQLLSEDTNDEDIQKELDSVNSELEKAQKERQENKQSNSETSLVDTSEEQTQTDEEKQAEEKAAEEKAAAEEKAKKEEQKEKEDEKKETEKKDEKKDDK", "output": "Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss) . Required to deliver LXG toxins to target cells ."}]}
+{"id": "function_test_981", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "METPSIDIQNIRAKYLNSHDPYLLESKLPTTSPFELFDIWFRNVASQSDLTFEEINAVSLSTVGKDLRPSSRMVLLKAYTPTGFSFYTNYTSRKGNQLEENPNAAMLFYWPKVNRQIRVEGVVEKLPDEMAVAYWNSRPVASRIGSKSSDQSKVVPDREFLESKKVALTELSVREGAQAITKPESWGGYHLIPRYFEFWQGQSDRLHDRIVFERDVDVWLLKRLSP", "output": "Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)."}]}
+{"id": "function_test_982", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADEFEDKVAKKRLIPDGCGVKYVPNRGPLDKWRALHS", "output": "Testis-specific component of the ribosome, which is required for the transition from prophase to metaphase in male meiosis I (By similarity). Compensates for the inactivated X-linked RPL10 paralog during spermatogenesis. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (By similarity)."}]}
+{"id": "function_test_983", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEFLKHYEDDEDQDDENNTKDENVNKINKRQHFEIENVIDEIPDLPLSFFENFKKIKHYSSEIIDETNKKTRLFEHVEGNYPTFIYFKVPTKSRNDIKELIEQVKEIGNEINIKQDTETCFHISISRTFPIREHHIETFTQELKKTLKNQRSIDIQLSKECCVFINDNQSRIFLSIPINQSFKSNILKLIERIDSCLSLFKFPKYYDNPEPHLSISWSLITNNNNETNDENINYIPLNKFKNKEIIRDNLKLTDSFKVSRIFWNIGKTESFIDLQ", "output": "3'-5' RNA exonuclease that trims the 3' end of oligo(U) tracts of the pre-U6 small nuclear RNA (snRNA) molecule, leading to the formation of a mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate. Participates in the U6 snRNA 3' end processing that prevents U6 snRNA degradation."}]}
+{"id": "function_test_984", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MESLSKYKLVFLGDQSVGKTSIITRFMYDTFDITYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSSVAIVVYDITNKVSFTNTIKWIEDVRNERGNNVVIMLVGNKTDLADKRQVSIEEGEAKAKEYDIMFTETSAKAGFNIKALFRKVASALPGIDSNSMTKNQHEIISEVDITDGGKPALKEGDGFCSSSRC", "output": "Protein transport. Probably involved in vesicular traffic (By similarity)."}]}
+{"id": "function_test_985", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAAPATRSRYLLRLTVTLGPRSRSYHAPPPPRRRPAPHWPDRENLMTPRWQLTPRYAAKQFGRHGAISGVPPASLWPSSEQLCELEAEEREWYPSLATMQESLRVQQQAAEARRQAREQHIAECMAKMPQMIENWRKQKRERWEKIQADKERRARLQAEAQEQLGYHVDPRSARFQELLQDLDKQQRKRLKEERQRQKKEARIAAMASAEGQDSAEAQDSAASGKPSS", "output": "Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis."}]}
+{"id": "function_test_986", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAGLVFLGLALSSGATVAKSEGGSLCSRSQVFFRDACYEFVPLEHTFPGAQGWCEGHGGHLAFIPDEDTQQFLQRHITQDREWWIGLTGGSGHNGTVGGSGTWLDTSNVNYSNWQEGQATPAPGSCGYIGSGPSSQWAALEDCTQTFAFVCEFGVGRSLACEGHNATMHCDSGEVILVQDAFYGHQTPYLCTRGIWPPSDLEGECGWVSVKDEVAGQCQGLQACQVAVDGTYFGDPCPTRGSYLWVQYQCLEGLRLVVPNGSFIFDNVTISLMWLLSPYTGNLSCVLSMGDGYTFDPYNPPSVSSNVTHQFSSPGEFTVFAECTTSEWHVTAQKQVILCEKVETPRITGCTGLAGAGVGLLCQAVFGEPLWVQVDLDGGAGATYAVLSHNRTLAEFTAQRGSQLYNLTLDRDIQEMLGPGRHHLKIQAVSNEGTGTASAPSGNFTVYFVEPLSGLRASWASDRVELGWDLVVNVSVARGTLEELTFEVAGLNANFSQEEESVGQSSGNYHVAVPAEGTFLVTVHVRNAFSELSLDIGNITVTASSSLQELSGINAEAKSGHKQDMKVFTEPELYVDPFTEVTLGWPDDDPGLNFHWSCGRCWAQWNACVGRQLLHTDQRLLVLHTFCLPPLNSAVTLHLAILRGQELEKETEQCLYVSAPLNLGPQISCEKNCRPVKADQDVLLTVTVGDETSVAVFSWYLDDTVPEEVEPLPAACRLRGFWPRSLTLLHSNSSVLLLNSSFLQTWGPVIPIRVTALTSHAYGEDTYMISMLPRPEVPACTIDPEEGSVLTSFTVSCSTPATLGPVEYCFCLPSGFCLHCGPEPALPAVYLPLGEEKDGFVLPVVISVTNRAGDIEQTQVAVKVGHSYTGVEDVTFQEMVSERIATALHQESGREQLLLFAKAVSSELNSEVQSPGSGQLGMDIKRKVRELMLRSLSVVTTGLQNMQRVQALAEVLREVTQRAEELTPAAQWEASCALQRATEALLVASTKVRPEDQRRQEATRAMFEAVGSVLEASLSHRSEEPMEANSSQVAYIVAQLLRVIDHFQSALLLGTLPGGLPAILVTPSISVYTDRIQPRSWQGSSVHTAAADSVTFTLPAATFLCPMEDSQEPVDIRMMSFSQNPFPSRSQFDVSGTVGGLRLTSSSGHPIPVKNLSQNIEILLPRISAHIEPKMLSLASREALSVNVTAGDTALGIQLHWGPGVPLILSLGYGYHPNETSYDAQTHLPPVAATGDLPTWILHPEDLPFGEGVYYLRVVPEADLESSSGRNLTVGITTFLAHCVFWDETQETWDDSGCQVGPRTTPSQTHCLCNHLTFFGSSFLVMPNAIDVRQTAELFATFEDNPVVVTTVGCLCMLYVLVLIWARRKDIQDQAKVKVVVLEDNDPFAQYHYLVTVYTGHRRGAATSSKVTLTLYGSDGESEPHHLSDPDAAVFERGGVDVFLLSTLFPLGELQSLRLWHDNSGDRPSWYVSRVLVYDSVVDRKWYFLCNSWLSVDVGDCVLDKVFPVATEQDRKQFSHLFFTKTSTGFQDGHIWYSVFCSATRSSFTRVQRVSCCFSMLLCTMLTSIMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLESSILMFPINLLIVQIFRNTRPRLPMGKDGRQKQGPPNLTPSAQPTEEGLLTPETGIQSLISSLFKALKVQPPASGWDSMNPVDINYLLTLMEDIICPESTEGPGFWEEAKGREDPITSTRGSVKPKENTWHPKPELAVRGLWKDSVYRRCLYLQLEHVERELQLLGPQGFLHHHSHAQALRQLHVLKGHLWGQPGTPALAYPSTSRVSKSPRGLPWWCVLVGWLLVATTSGVAAFFTMLYGLHYGRVSSLKWLISMAVSFVESVFITQPLKVLGFAAFFALVLKREDDEETLPLFPGHLSSPGPGVLFRSRRHSSERAYQPPPMAAIEKMKTTRLKEQKAFALIREILAYLAFLWMLLLVAYGQRDPNAYHFHRHLERSFSQGFSPVLGFRGFFEWANTTLVKNLYGHHPGFVTDGNSKLVGSAHIRQVRVRESSCAVAQQLQDSLDGCHGPYSLGIEDLVDYGEGWNASAYNNSNGFPQAWRYQSQSQRRGYPMWGKLTLYGGGGYVVPLGTDHQSASRILQYLFDNSWLDALTRAVFVEFTVYNANVNLFCTVTLTLETSGLGTFFSHVTLQSLRLYPFTDGWHPFVVAAELTYFLFLFYYMVVQGKLMRKQKWGYFCSKWNLLEVAIILASWSALVVFVKRTILADRDLQRYREHREGISFSETAAADAALGYIIAFLVLLSTVKLWHLLRLNPKMNMITSALRRAWGDISGFVAVILIMLLAYSFASNLVFGWKLRSYKTLFDAAETMVSLQLGIFNYEEVLDYSPILGSLLIGSCIVFMTFVVLNLFISVILVAFSEEQKSDQLSEEGEIADLLLVKILSFLGIRCKREETWSSSEQPELPPQALAPQPAQALSRV", "output": "May function as an ion-channel regulator. May function as a G-protein-coupled receptor (By similarity)."}]}
+{"id": "function_test_987", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTGIDLNTVEEDEEEAAEEVAANGSSPAPARAGAVCLELWHACAGPVAPLPRKGGVVVYLPQGHLEHLGDAPAAAAAAAAVPPHVFCRVVDVTLLADAATDEVYAQLSLVPEKEEVARRADDGEGEDGDGMKQRFARMPHMFCKTLTASDTSTHGGFSVPRRAAEDCFPPLDYSQQRPSQELVAKDLHSTEWRFRHIYRGQPRRHLLTTGWSAFVNKKKLVSGDAVLFLRGDDGELRLGVRRAAQLKNGSAFPALYNQCSNLGTLANVAHAVATESVFNIYYNPRLSQSEFIVPYWKFMKSLSQPFSVGLRFKMRYESEDATERRYTGIITGSGDTDPMWHGSKWKCLLVRWDDDAEFRRPNRVSPWEIELTSSVSGSHLSTPHSKRLKPCLPHVNPEYMVPRGGGCPDFAESAQFHKVLQGQELLGFKSHGGTAAATSQPCEARHLQYIDERSCSSDASNSILGVPRLGDRAPLGNPGFSYHCSGFGESHRLQKVLQGQELFRPYRGTLVDASMGSNGFHQQDSPRAPGVVNKWQAQLHGRAAFHGPPALALPSQSSSPPSVLMFQQANSKMPRLEFGHGQLDKHENDRRVRFGPSEGIERREQRIPLQPYPTSGEVIDGQVTVEKSHSPGRHGKDGPDNKAVGTNSCKIFGISLTEKVPAREELDDGDANYSLQSLKQVPKSLGNSCATVHEQRPVVGRVIDISTMDMMI", "output": "Auxin response factors (ARFs) are transcriptional factors that bind specifically to the DNA sequence 5'-TGTCTC-3' found in the auxin-responsive promoter elements (AuxREs)."}]}
+{"id": "function_test_988", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MALFSVRKARECWRFIRALHKGPAATLAPQKESGERVFSGIQPTGILHLGNYLGAIESWVNLQEEYDTVIYSIVDLHSITVPQDPTVLQQSILDMTAVLLACGINPEKSILFQQSKVSEHTQLSWILTCMVRLPRLQHLHQWKAKAAKQKHDGTVGLLTYPVLQAADILCYKSTHVPVGEDQVQHMELVQDLARSFNQKYGEFFPLPKSILTSMKKVKSLRDPSSKMSKSDPDKLATVRITDSPEEIVQKFRKAVTDFTSEVTYEPDSRAGVSNMVAIHAAVSGLSVEEVVRSSAGLDTARYKLLVADAVIEKFAPIRKEIEKLKMDKDHLRKVLLVGSAKAKELASPVFEEVKKLVGIL", "output": "Mitochondrial aminoacyl-tRNA synthetase that activate and transfer the amino acids to their corresponding tRNAs during the translation of mitochondrial genes and protein synthesis."}]}
+{"id": "function_test_989", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDPEDRSEIAFFDVETTVPKRGQRFAILEFGSILVCPKKLTELRSYTTLVQPADLSLISSLSVRCNGIKRDDVVLAPLFADIADTVYDILHGRIWAGHNILRFDCARIREAFAEIGRQPPEPKGAIDSLGLLTQKFGRRAGDMKMATLARYFGLGNQTHRSLDDVRMNLEVLKYCATVLFLESSLPYAHVDNSVSPETISSRRRIDASREGNTVTTSVRLPSISENSAAQPDPFNMSVLRNEMASDNHIQSDILMEEEQIEPSDVVASENTSDHEGFLTPDAMSLSNIKAMLFPFYPGSQMMKLKLLHGDSPLQLYCSYLKIRFGVNGKFLDNTGRRRLNFVVDLNPSLYSILEACDSNAQKLSVDSGSTSEWNPVVNPMKGFVNYPNARIHIATEINGDEARYATEIHQRESSGATQKLIFSNPNNEELESLLTTGSVVDAFLSLEPYDYQQKAGIRLVAKKLVIQS", "output": "Probable exonuclease involved in enuclation of sieve elements."}]}
+{"id": "function_test_990", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEGGGGERAAGVVRRLMAAKAESRKSFSEIGEEAGLTNVYVAQLLRRQAQLKPETAPALRAAVPGLTDDLVALMMEPPFRSYHPDIVHEPAIYRLNEAVMHFGESIKEIINEEFGDGIMSAIDFYCSVDKVQGADGKDRVVVTFDGKYLPYSEQRSDHMMSRLTRKTS", "output": "Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide."}]}
+{"id": "function_test_991", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDLERLSPRNPVKKESWWTVLTLAYQSLGVVYGDLATSPLYVYKSTFAEDITHSETNEEIFGVLSLIFWTLTLIPLVKYVFIVLRADDNGEGGTFALYSLLCRHARISSLPNFQLADEDLSEYKKNSGENPMRLKVPGWSLKNTLEKHKFLQNMLLVLALIGTCMVIGDGVLTPAISVFSAVSGLELSMSKQQHQYVEVPVVCAILILLFSLQHYGTHRLGFVFAPIVLAWLLCISTIGVYNIFHWNPHVYKALSPYYIYKFLKKTRKRGWMSLGGILLCITGSEAMFADLGHFTQLSIQIAFTFAVYPSLILAYMGQAAYLSKHHVLQSDYRIGFYVSVPEQIRWPVLAIAILAAVVGSQAIITGTFSIIKQCTSLGCFPKVKIVHTSSRMHGQIYIPEINWTLMLLCLAVTVGFRDTKHISNASGLAVITVMLVTTCLMSLVIVLCWRKSSLYALAFIFFFGTIEVLYFSASLIKFLEGAWVPVALSFIFLLIMYVWHYGTLKRYEFDVQNKVSINWLLTLFGSSNLGIVRVHGIGVINTELVSGIPAIFSHFITNLPAFHQVVVFLCVKSVPVPHVKPEERFLVGRVGPKEYRLYRCIARYGYRDVHKDDVEFENDLICSIAEFIRSDKPLNYSPDPENESGINERLTVVAASSSNLEGVQIYEDDGSDKQEPSSSSEVIMVAPSPRFKKRVRFVLPESARIDRSAEEELTELTEAREAGMAFIMGHSYVRAKSGSSVMKKIAINFGYDFLRRNSRGPCYGLSTPHASTLEVGMVYIV", "output": "Probable potassium transporter."}]}
+{"id": "function_test_992", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSRHKSKKLIIEDDEPKQDELNPFSFKEFIRNKNQPSCSTEATEVYNGACLVEQDYNTSIDFATKGPFFTDPSALCQPPESEPDETWIESHQRSAIEGSPDFELCGASDISAYSEQSSLCSDEREAAEWELGQSDFLPKKHLSRISTGSYEGDEETSVIDISFHHKRGNAENGTKNLQQLREENSLLRKQVKELVRMSETDSRRIKQLTDEMHNKKLQEEKEANDLEAMVQSVEQNLQLMTKRAVKAENNISKLKQEMLKLQGQLEDYKSENERLRLGETAALATMRHNAQVASEYLNKAAQDAEISINSC", "output": "Endosome-associated protein that plays a role in membrane receptor sorting, cytokinesis and ciliogenesis."}]}
+{"id": "function_test_993", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEEDMYVDIFLDPYTFQDDFPPATSQLFSPGAPLDVHPLNPSNPETVFHSHLGAVKKAPSDFSSVDLSFLPDELTQENKDRTVTGNKVTNEESFRTQDWQSQLQLPDEQGSGLNLNSNSSPDTQSCLCSHDADSNQLSSETPNSNALPVVLISSMTPMNPVTECSGIVPQLQNVVSTANLACKLDLRKIALNAKNTEYNPKRFAAVIMRIREPRTTALIFSSGKVVCTGAKSEDESRLAARKYARVVQKLGFPVRFFNFKIQNMVASCDVKFPIRLEILALTHRQFSSYEPELFPGLIYKMVKPQVVLLIFASGKVVLTGAKERSEIYEAFENMYPILESFKKV", "output": "Transcription factor required in complex with TAF3 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process (By similarity)."}]}
+{"id": "function_test_994", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAVELMTRNYISGVGADSFAVQEAAASGLKSIENFIGLMSRDSFNSDQPSSSSASASASAAADLESARNTTADAAVSKFKRVISLLDRTRTGHARFRRAPVHVISPVLLQEEPKTTPFQSPLPPPPQMIRKGSFSSSMKTIDFSSLSSVTTESDNQKKIHHHQRPSETAPFASQTQSLSTTVSSFSKSTKRKCNSENLLTGKCASASSSGRCHCSKKRKIKQRRIIRVPAISAKMSDVPPDDYSWRKYGQKPIKGSPHPRGYYKCSSVRGCPARKHVERAADDSSMLIVTYEGDHNHSLSAADLAGAAVADLILESS", "output": "Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (By similarity)."}]}
+{"id": "function_test_995", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKFMKLGTKPDSFLSKGDNVRYVTNELETEIIIIIGNVKFYLHKFPLLSKSGFLQKHIATSKNEEEKKNQIDEIDISEIPGGSVAFEICVKFCYGITVTLNAYNVVAVRCAAEFLEMNETFEKSNLVYKIDVFLNSTIFRSWKDSIIVLQTTKDLLSDDSEELVKRCLGSIASTASIDTSKVKWSYTYNRKKKLEKVRKPEDGVPKDWWVEDLCELHIDLYKQAIKAIKNRGKVPSNVIGEALHAYAIRRIAGFSKESMQLIDRSLINTIIELLPDEKGNISSSFLTKLHRASIFLGCEETVKEKLKKRVSEQLEETTVNDILMYDLDMVQSLVKEFMNRDPKTHSKVSVAKLIDGYLAEKSRDPNLPLQNFLSLAETLSSFPRHSHDVLYRAIDMFLKEHSGISKSEKKRVCGLMDCRKLSAEACEHAVQNERLPMRVIVQVLFFEQIRANGSSTGYSTPELTTTTLNTEDDEWDHEKEF", "output": "May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). May play an essential role in auxin-mediated organogenesis and in root gravitropic responses."}]}
+{"id": "function_test_996", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAAAHRCLFLLLLSTCVALLLQPPLGALGAPLEPEYPGDNATPEQMAQYAAELRRYINMLTRPRYGKRDKEGTLDFLECGSPHSAVPRYGKRDKEGTLDFLECGSPHSAVPRWVFSLSCVPRCLGQENGGV", "output": "[Pancreatic polypeptide]: Hormone secreted by pancreatic cells that acts as a regulator of pancreatic and gastrointestinal functions probably by signaling through the G protein-coupled receptor NPY4R2."}]}
+{"id": "function_test_997", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAADLAFEATELRLGLPGGGGDGDAAAAAARSSSGKRGFAETIDLKLKLEPAAAAVDDDDDKEEAAADDREKKVDIVGADNDDASPPAAAAAGGMKRSPSQSSVVTAAADPEKPRAPKAQVVGWPPVRSYRKNILAVQADKGKDAADGGGDKSGAGAAAAAFVKVSMDGAPYLRKVDLKMYKSYLELSKALEKMFSSFTIGNCGSHGVNGMNESKIADLLNGSEYVPTYEDKDGDWMLVGDVPWEMFVESCKRLRIMKGSEAIGLAPRAMEKCKNRS", "output": "Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations."}]}
+{"id": "function_test_998", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MATSFFRRLARSAPITFPVAFGSQSKSGSGAFRFSTGAIAALSGGFSYYYLTSGNNLVYLDQAKEETGPKTALNPDKWLEFKLQDTARVSHNTQLFRFSFDPSAELGLHVASCLLTRAPLGYNAEGKTKYVIRPYTPISDPEAKGYFDLLIKVYPDGKMSQHFASLKPGDVLEVKGPVEKFKYSPNMKKHIGMIAGGSGITPMLQVIDAIVKNPEDNTQISLLYANVSPDDILLKQKLDVLQANHPNLKIFYTVDNPTKNWKGGVGYISKDMALKGLPLPTDDTLILVCGPPGMMEHISGGKAPDWSQGEVKGILKELGYTEEMVFKF", "output": "Desaturation and elongation of fatty acids."}]}
+{"id": "function_test_999", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MITKDVKEQLIQVSGPENFDDSNAGRLVYSYDATPQYQSMPDAVIAPRNTDEISRILTICSEHRVPIVPRGSGTNLCGGTCPTEGGLVLLFKHMNQILEIDEENLTATVQPGVITLDMIRAVESKGLFYPPDPSSMKISTIGGNINENSGGLRGLKYGVTRDYVIGLEVVLANGDIIRTGGKLAKDVAGYDLTRLFVGSEGTLGIVTEAIVKLVPKPETKKTLLALYENIDAAAQTVSDIIAAKIIPATLEFLDQPTLLVIEDYAKIGLPTSAKAVLLIEQDGPFETVERDMEKIEAICKKGDAVSVQTAQTEEEAFALTEARRSALSALARLKPTTILEDATVPRSEIANMVKAINDIAAKYDISICTFGHAGDGNLHPTCTTDIRNKDEMERVEQAFAEIFEKAIELGGTITGEHGVGEMKAPYLEMKLKKEGIDAMKALKAAFDPRNILNPGKMFAKDARKRVVAER", "output": "Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. Is also able to oxidize D-lactate ((R)-lactate). Does not link directly to O(2), and 2,6-dichloroindophenol (DCIP) and phenazine methosulfate (PMS) can act as artificial electron acceptors in vitro, but the physiological molecule that functions as primary electron acceptor during glycolate oxidation is unknown."}]}
+{"id": "function_test_1000", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTSRMQPKSGVYSVSKADFTKIFEDVPKVPITSAVDLRNKFDAVRIILSNSSEDWNKRQTQLKTVRSLVIHGEKVVDRPTMIAHLVQLLGCFELAVKDLRSQVLREAAITCSFIVSKYGIETHSIGEDILVPAMSQVAVSTKIMATSASTLTEFIVEYVQTRQVFTILSSFSTSKDKSQRRQLAALLEIVISKWSDRIKKQIMRQICELIKSAINDADSETRAAGRRAFAKLDEMHSEEADALYLELDHSKQKMLRGGDAASSWASVNSEKGSIPIRSKLSAGSKAHMNISAKFLAQRSASAIDPKATKFAGPSRLVRPTSTKTMARQDTSPAGCKYSNFISMFFKTLLLSAKIPYPNRPGSRTRTSSITSTDSRDTSPTRRNSPLPPETQKARVKYGNGSFFAKLGMPDTTDDDEFLLPIRIRSPLKTPTIEAHDKVSQVLKECCSSSVSEKKEGIKKLLPIVADTSLNPIEIKNIGNCLNRLLSDASNTMVLEIYSIFVRTHSSRLSEWLRLALAKLFARKAAETLPNTKKQIGHTLNVILECFNAHHQLVTVCELMCDPIHLMVPKARVVLLEYLTSLLDEYTEPGASINAKELKTAIRKMLTWASDPRLSILLTPHVEKAICSMFCVNVADFSALISDLDSEQKNWIHQTLQRNGLENGISSNNIATNSGATASRETSNTSFQKESTSFGLPEFGARKGGTGVNLGSLNISNNLALSRLEEQSTSRLMEKVNLNSTVTLPPDTLEKIQNVQDLLQKMRSSENADEQESAISSIYMMICDGGFGVWEQCYAKLLLNLFEILSKSRSENNKKMCLRILGKMCTAQAAKLFDSTEMAVCKVLDAAVNTNDATTALAVEDCLRTLATHLPLSNIINIAKVILNQEPIDDERASLVLKMVTRLFEELPAEELNNIVDDITPTIIKAYQSTSSTVRKTVVYCLVAMVNRVGEQRMTPHFTKLPKAMTNLIQVYVNRAISTSLPRL", "output": "Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules."}]}
+{"id": "function_test_1001", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSSIGTGYDLAASTFSPDGRIFQVEYAQKAVDNAGTMIAIRGKNGVVVVADKLISSKLYTDNANPRMFNVNDNVGVAVAGNYPDGFALKNYAYGEAMKWLKDYREPMPIQNIANSVAEYIHIHTLGISRPFGAGAFFMSWNKQTGGRLFLVEPSGLNYEYKAWAVGKHRQAAKAEIEKLKIEELDVNQLVKEAARIIMVVRDENKDKNVQIEMGWVGEQTNGKYEEVPSEVVTAAEEWAIAKLDEDDMDD", "output": "The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity)."}]}
+{"id": "function_test_1002", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRRFYIFLLLIPYINGTINDDSLPMVITTWGSDGFKKATKNAVDATLLGGRMFGLVEGLSTCEALQCDTTVGYGGSPDENGETCLDSLVIDADGMRVGAVANLHRIRDAARVAWGVMNFTKHTLLVGESATQFAKTLGFKEEDLSTEETKSWISKWKTEKCQPNFWKNVSPDPSSSCGPYKTNPLTKSMRYYSLVNQSDEAGYLVEKTNHDTIGMVVRDTENIFSAGTSSNGARFKIPGRVGDSPIPGAGAYANKFGGAAATGDGDVMMRFLPSFFAVTQMELGTKPSKAAYKAITRILKVFPKFSGAVVAMNVKGRIGASCANINKFGYNVAFQNGTVVTYSISCLKEVNSLKYLKEGIEFA", "output": "Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins."}]}
+{"id": "function_test_1003", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEITSSAMLKPAPTPTPHPLAGEKVPLTAFDRAAFDVFVPMVFAYRAPAPSSEAVKEGLRMAVAAYPLAAGRLAVDVAADGQGRRRRRRVLHVNDEGALVLDATVEADLDAVLAANVATDLYPAPPEHSFGAAVLQVQLTRFRCSGLVVGLIVHHHVFDGHSTSAFCTTWARAVRDGEAFSVPSPCLDRAITSVPRSPPAPVFDHRSIEFKVGNKSSDSSGAAAAAVEKITNIGVRFTAKFVAELKARVGGRCSTFECVLAHAWKKMTAARGLKPEEFTRVRVAVNCRRRANPPAPADLFGNMVLWAFPRLQVRRLLSASYRDVVGAIRAAVARVDGEYIQSFVDYVEVADARGEELAATAAEPGETLCPDLEVDSWLGFRFHEMDLGTGPPAAVLSPDLPIEGLMILVPVGGDGGGVDLFVALADDRAQVFEQICYSLEEHAIPSHL", "output": "Hydroxycinnamoyl transferase that catalyzes the transfer of an acyl from benzoyl-CoA to tryptamine, to produce benzoyl tryptamine. Serotonin and tyramine serve as acyl acceptors in vitro. Specific for benzoyl-CoA as acyl donor. Has no activity with p-coumaroyl-CoA, caffeoyl-CoA, or feruloyl-CoA as acyl donors."}]}
+{"id": "function_test_1004", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKFHLFFFILLFGATILTAKKSYPEYGSLDLRKECKMRRGHCKLQCSEKELRISFCIRPGTHCCM", "output": "Has bactericidal activity.; "}]}
+{"id": "function_test_1005", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIILKRNIVFLLIIIIVLGIFIATSIEIKNYKLSLNQNKNEISKNPPIWPAPFYGQFGNNSILISKEFNFTIISDSTLLLNKTLSKYYNLIFTQDNLINSSSNTLNKLNINLKSKNEILKFGFDESYKLIIKNNENSKLEGNTVYGIMRGLETFYQLIKYNFSDNSYFIENCLPLIINDKPRFPHRGVMLDTSRHFYSVDTILKVIESLSYNKFNTLHWHIIDSQSFPLSSKSYPNLINGAWSKSEIYSYHDIKRIIKYGKENGIRIQLEIDMPGHAKSWSVGYPDLLPHGWNDSTTTIKCPDYDVPLDPSSPLSLPISFGLLSEFSGTDYGYNPNYDDKSNNLFNLTVDDLFHVGGDEIEYQCWNNSKRIKDWMNENNLKTFQDVAKQFQLKIIKQLLKIGKIPVLWEDTFQLFYKDLPKDVIVEIYHDQSTAINATNNGYKIISSIARYWYLEYSYSNWIRAYNFEPTLNISKSNIHLVLGGEGAIWSESIDSSNLFQKLYPTSSAIAERLWSPIYYTNLLNAKSRLQSFRCSLLKRGINSAPLNNSSPLSAFSCYNS", "output": "Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines."}]}
+{"id": "function_test_1006", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MATTFEQMRANVGKLLRGIDRYNPENLATLERYVDTQARENAYDLEANLAVLKLYQFNLAYFQTTVTAQILLKALTNLPHTDFTLCKCMIDQTHQEERPIRQILYLGNLLETCHFQSFWASLEENRDLIDGITGFEESVRKFICHVVGITYQNIEYRLLAEMLGDPLDTQVKVWMNKYGWTENEDGQIFIHNQEESVKPKNIVEKIDFESVSSIMATSQ", "output": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation."}]}
+{"id": "function_test_1007", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAKAGEKSGGGGKRGLKRKAPAEEPQETAVASDGTAESGVQSAKAAAFPPGFSISEIKNKQRRHLMFTRWKQQQRKEKLAAKKKLKREREALGDKAPPKPVPKTIDNQRVYDETTVDPNDEEVAYDEATDEFASYFNRQTSPKILITTSDRPHGRTVRLCEQLSTVIPDSHVYYRRGLALKKIIPQCIARDFTDLIVINEDRKTPNGLILSHLPNGPTAHFKMSSVRLRKEIKRRGKDPTEHVPEIILNNFTTRLGHSIGRMFASLFPHNPQFIGRQVATFHNQRDYIFFRFHRYIFKSEKKVGIQELGPRFTLKLRSLQKGTFDSKYGEYEWVHKVCAYCSKAI", "output": "May be required for ribosome biogenesis."}]}
+{"id": "function_test_1008", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEVQESGSGSAESGTQEPSPVPSKTTGHYELPWVEKYRPVKLNEIVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAVLELNASNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTTRFALACNASDKIIEPIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIFTAQGDMRQALNNLQSTFSGFGYINSENVFKVCDEPHPLLVKEMIQHCVDANIDEAYKILAHLWHLGYSPEDVIGNIFRVCKTFPMAEYLKLEFIKEIGYTHMKVAEGVNSLLQMAGLLARLCQKTMAPVAS", "output": "The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP (By similarity)."}]}
+{"id": "function_test_1009", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGKGCKVVVCGMASVGKTAILEQLLYGSHTVGAETSDTQEDIYVASVETDRGVREQLRLYDTRGLREGLDLPKHFFSVADGFVLVYSVDCLESFKKVEVLKKEIDRSRDKKEVMVMVLGNKCELRERRQVDQDTAQQWARGEKVKLWEVTVTDRSTLIEPFTSLTSRLTQPQSKSAFPLPGRKSKGTPSNDI", "output": "Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation."}]}
+{"id": "function_test_1010", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MECMASTEESLPASSSMDSCSGELPTTTTTAPAQSTASSGCRPPATAAKRRSLISTDLRLGLTLSSVVHIDGNNPSTPRSSLTTATVTADRGGGGGGHGRRRSLFVKVYMEGVPIGRKLDLLPLDGYKGLVARLASMFRASITYHHCHRQFAVVGMKTNKVHHVLTYEDQEGDWMMAGDVPWELFLTSVKRLRIARADDKYCYSC", "output": "Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations."}]}
+{"id": "function_test_1011", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQSTSSTSSGSCSRPLEGSTLNSGGSAENVARDGGSGDDSVGIGDENPSGSSAATNGHDSKHNGFIVNNNGSSSRIVDGENNRENTSCSGVQLDKSNQEIIRLIGQYLHDVGLDKSVQTLMLESGCYLEHPSATKFREHVLMGDWSKADSDLKDLEPLIDNGKLATITEMKFILLEQKYLEHLDDGNPLDALHVLRSELTPLQHNITRVHQLSSYMMCSTNQDLYQRAKWEGKGILSRALVMERLQTFMPPSVMMSPRRLRTLLQQAVELQSQHCPCHDMAWETNLETVSLLTDHCCTTDGFPMQTIQILTDHCDEVWFCKFSPDGLKLATGSKDSTVIIWDVDPYKLTLKHRRVLDGQAQLSVSFVSWSPDSKLILVGGTEDSHELYIWNVDDGKLVVKFSQSLEDSLACGAFSRDGARFVCGGQKGQLYLCDLNGTIVDSWEGVRVNSIAFRADNKTILAADNHYRIRGYNFDSPRSDFDILREPHPIMTFSINSADRLALLNVSNQGLHLWDIEDKCLVRRFQGIRQSNFAIHSCFGGVNESFVASGSEDKVVYIWHIKREEPLAKLAGHTKTVNCVSWNPVYPSLLASASDDATVRIWGPKPNGSSATTESDDCSSSSSSSSWNMT", "output": "G-beta-like protein involved in cell signal transduction (By similarity)."}]}
+{"id": "function_test_1012", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAVAAVGRPRALRCPLLLLLSLLLVAGPALGWNDPDRILLRDVKALTLYSDRYTTSRRLDPIPQLKCVGGTAGCEAYTPRVIQCQNKGWDGYDVQWECKTDLDIAYKFGKTVVSCEGYESSEDQYVLRGSCGLEYNLDYTELGLKKLKESGKHQGFSDYYHKLYSSDSCGFITIAVLFVLAFAVYKLFLSDGQGSPPPYSEHPPYSEHSQRFASAAGAPPPGFKSEFTGPQNTGYGASSGFGSAFGGQGYGSSGPGFWSGLGAGGLLGYLFGSNRAATPFSDSWYHPAYPPSHSGAWNSRAYSPLGGGAGSYCASSNADSRTRTASGYGGTRRR", "output": "Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions (By similarity)."}]}
+{"id": "function_test_1013", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLVRNICKFTQVMGRFRVVVNPRDYCHLAPLKRSRYHQRSEFGCRPLCSNAAGYEVSWAAPPASGSSGGMFWAFSAAFTLNLFGGADEKEETPEEKLIKTIKRSILCIQREQYDKAEQMLHLALRMAQDIQSKDGITYVFDLMANLAMEREQFKKAEKIFTDVMKRLFAEGHTEESPKILHISSKIAHMSQLQGDLEKSFQGFTWTLQQLAKLLEKMPDDKDILELYGLTKNWFGQLLMKQGKYLEAKNLFKEAFDTLINVYGAVNDASVTILNNISVAYVNLEKYAEARETLLEAMELTKELKDATQEGILQANLGLVYLREGLMSQAENACRLAWKLGKQHQNPDAVEQAEYCLNEIKTTLNGEKRQ", "output": "Required for mitochondrial complex III formation."}]}
+{"id": "function_test_1014", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MYKKMSLRQLFSDRPPLNAVLQEKAQKLRYACSPSKCIHSLLSFLPIITWLPKYDWSHSFFGDLSGGLTMAVFSVPQGIALASITGVPPVYGLYTAIFPSFLYIFFGTSKHNALGGFAVLSLMTHGAIEKVMLRTATSYNATAYVNHTLDELLDKENETALISNTTLMQILGNETSFVEEVTMEMWTEGVTPVKQIHVATTIIFLAGVIQVFMGVFRLQYLTSLFSEQVMSGFVVGGGIHVFFAQIGNMLGIELPRRSGPGYLYYRIWDLVENLDNVHIPTVCISLSSFLFLVFGKEYLAPWLNSAFNYPVPFELVLVVVGITATNYAELSLRHDVKVVGNIPTEFPPPSLPRFDLIRHIGLNAAAIAITAVAIHITVAKVVEKRYKYKINHGQELYALGFVGVLSSFFPVFPVTSGFARSVVGAAVGGSTQLTCLFSSLALLSVILCIGPALEYLPQCILSAMIIFAQKGMLEKFGELKSLWPVFKIDFTIWLMSFFLTVCYDMGEGLLMAIGFAVLTTIIRTQRPKWHFLSRDDDTENYKETKKRDLERIQGNVCIFRMDAPLIFTSSDRFTMSVWQCVKKWERCKSESFVTIEQMNSDRSADIFDSKLKSARRRWKRDQKSENRCKLVIDCDGFPYVDYLGLSTLKSVYVDLQAAGIQCFFVVQKSDLKKLFRATDFYEVVDESKVFNKVGDAVKAAEQHISSPKTTKEILTALASIATTDTVLIDEESSDSNDNDDAEIQERITEESENSEEVMSETSVSIEDATSLTSSRNSINSEE", "output": "Possible sulfate transporter."}]}
+{"id": "function_test_1015", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSNPTDNNSATSSITPNFSAFSSFTTYKPSDSFSSFESDSSPSKSSSSRKNRDKIADKKQRRNRTTFTTFQLHALEAAFDKTHYPDVYARETLAAKVQLPEVRVQVWFQNRRAKFRRQEKQDCQGEEKHSLKDTMPSWSWMSENKTDTPPMLPPANTLSSTHNNGISDEFFKTSEGKEVYGFPFAEYGTPADNTHVSKTGNVFHLNFEDSDKKSMKKESPQTPSTSSPFISEYHPPFIPYYIPNQSFSNAFNQYPMPFPYPIHFEPPQLTHSQENC", "output": "Required for cell specification of the RIA interneurons."}]}
+{"id": "function_test_1016", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKLLFFLFGLIFAVEQEKPYLDNNRVPVEQILNDHSSAKFDYTYVSVCVNSTDETLLDIVYAKECKNAASRVALGKYSNQVNTTGWGILEIETFASHSYDVQAYGAGVAEGELTRLQIYYHYRNTIETMCNNHTLFCKRLYIYLQQNLDWMRSQVQANPPTDPFWRQVNLTFAQLTGIYDAYSKRNLTPEIGFDLHPIYMMQLAGDMFDLNKLLNKTADPMEYPEGGRCSGFVKLAPGNKDMFMAHVSMSSLSWMQRVLKIYKFGYDVNEVPGHIVTFSGYPGVLISTDDYTITSAGLTSIETTIAIFNQTLYTDKFMKPEGQVHCWIRSMISNLLSRTGKQWVDMFGRYNSGTYNNQWTVLDWKQFTPEKELPDKDVLWISEQTPGYYETRDMTWYLKKYTYFASYNIPFLPKVSEISGFDNKARQFAWFDWGGSPRARIFDRDHSKVTDIDSLTKLMRYNDYTHEEFARCKCTPNPYTGEGGISARGDLNTPGGTYEVESMGFRDHAGLDFKGTNYEMFKKMRFRAWGGPPYDPLPVFDWNHTNLTNVRHFGQPDVWNFTYVDLEWQLAAQVQLTPYDN", "output": "Putative phospholipase."}]}
+{"id": "function_test_1017", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNNSTTTDPPNQPCSWNTLITKQIIPVLYGMVFITGLLLNGISGWIFFYVPSSKSFIIYLKNIVVADFLMGLTFPFKVLGDSGLGPWQVNVFVCRVSAVIFYVNMYVSIVFFGLISFDRYYKIVKPLLTSIVQSVNYSKLLSVLVWMLMLLLAVPNIILTNQGVKEVTKIQCMELKNELGRKWHKASNYIFVSIFWVVFLLLIVFYTAITRKIFKSHLKSRKNSTSVKRKSSRNIFSIVLVFVVCFVPYHIARIPYTKSQTEGHYSCRTKETLLYAKEFTLLLSAANVCLDPIIYFFLCQPFREVLNKKLHMSLKVQNDLEVSKTKRENAIHESTDTL", "output": "Receptor for UDP-glucose coupled to G-proteins."}]}
+{"id": "function_test_1018", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSPFLKFFLFLYDYLSPSSFFLVQRNTLGASLDTTDGVVRSGIIGEIIYIWKQTRIFVFIPILKCLVTICLVMSLLLFIERVYMSIVVVFVKLLRRTPEKVHKWEPINDDDLELANTNYPMVLIQIPMYNEKEVCQLSIGAACRLSWPLDRMIVQVLDDSTDPASKELVNAECDKWARKGINIMSEIRDNRIGYKAGALKAGMMHNYVKQCEFVAIFDADFQPDPDFLERTIPFLIHNHEISLVQCRWKFVNANECLMTRMQEMSLNYHFVAEQESGSSIHAFFGFNGTAGVWRIAALNEAGGWKDRTTVEDMDLAVRACLHGWKFVYVHDVEVKNELPSTFKAYRFQQHRWSCGPANLWRKMTMEILQNKKVSAWKKLYLIYNFFFIRKIVVHIFTFVFYCLILPTTVLFPELQVPKWATVYFPTTITILNAIATPRSLHLLVFWILFENVMSMHRTKATFIGLLEAGRVNEWVVTEKLGDTLKSKLIGKATTKLYTRFGQRLNWRELVVGLYIFFCGCYDFAYGGSYFYVYLFLQSCAFFVAGVGYIGTFVPTV", "output": "Probable mannan synthase which consists of a 4-beta-mannosyltransferase activity on mannan using GDP-mannose. The beta-1,4-mannan product is the backbone for galactomannan synthesis by galactomannan galactosyltransferase. Galactomannan is a noncellulosic polysaccharides of plant cell wall."}]}
+{"id": "function_test_1019", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNIPSGTFSRSDHFHASSDASLFSSSLPLIQHQNINPRDSYHQSVDEMASGLDHFSGGIGNMLDDGDSHPIGNMLPDDEEELFSGLMDDLNLSSLPATLDDLEDYDLFGSGGGLELETDPYDSLNKGFSRMGFADSNVDNVMPQNIFQNGVGSIAGEHPYGEHPSRTLFVRNINSNVEDSELQALFEQYGHIRTLYTACKQRGFVMVSYNDIRASRAAMRALQGKLLKKRKLDIHFSIPKDNPSEKDVNQGTLVVFNLAPSVSNRDLENIFGVYGEIKEIRETPNKRHHKFVEFFDVRSADAALKALNRTEIAGKRIKLEHSRPGGARRNMMLQMNPELEQDDSYSYLNHVESPLASSPIGNWRNSPIDHPLQSFSKSPIFGNLSPTKNIRYPEFSMKTASVNNDQEGRRFSHLDHLFSSSSYNNASHKASTFQQPQSFGSVSSFGSLNSHPSHVETLSGSEFLWGSPSSSAWPVNPFSSNRENHRFPYSAQNGSLHQLHHIGSAPSGFFPRSPETSSMGSVAFRGASGNMNAQRNLRETSSPNFKMLSAPRRSQLFTGNGSYLWPAATMVSIDDPLEDGSNQQFDSNGNQADIKIQFQLDLSKIMRGEDPRTTLMIKNIPNKYTRNMLLAAIDEKNSGTYDFLYLPIDFKNKCNVGYAFINMVSPKFTIALYEAFNGKKWDKFNSEKVASLAYARIQGKAALIAHFQNSSLMNEDRRCQPIVFDGSESKYPIIRENSQLEASNSTVSHPLVGENTHQS", "output": "Probable RNA-binding protein that plays a role in meiosis and vegetative growth."}]}
+{"id": "function_test_1020", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MATGTDQAVGFGLVAVSLIIFTYYTTWVILLPFIDSQHVIHKYFLPRAYAVLLPLAAGLLLLLFVGLFITYVMLKSQKITKKAQ", "output": "Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. Part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynthesis. May act by regulating the GPI-GNT complex."}]}
+{"id": "function_test_1021", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSGFVGILVSDPWLQNQFTQVELRSLKSHFTSMKRESGKLTVSDLASRMGKSKVVGDQNLSNEERATLIQNFHPNLNDEVDFEFYLRIYLNLQAHVNAIIGSGVKNSSAFLKAATTTLLHTISDSEKSSYVAHINNYLSGDEFLNKCLPINPSSNDLFEVAKDGVLLCKLINVAVPGTIDERAINTKSMLNPWERNENHTLCLNSAKAIGCTVVNIGTQDIIEGRRHLVLGVISQIIKIQLLADLNLKKTPQLVELVGDSKDVEELMSLPPEKILLRWMNFQLRKTEYKKTVTNFSSDVKDAEAYTNLLNVLAPEHKNPSHLAVKSSFERAKLVLEHADKMGCRRYLTAKDIVEGSPNLNLAFVAHIFQHRNGLSTQTKQISFLENLADDIQISREEKAFRFWINSFDGSVYINNVFEDLRDGWILLQTLDKVSPGIVNWKVSSKPPIKLPFKKVENCNQVVKLGKQLKFSLVNIAGNDIVQGNKKLILAYLWQLMRYNILQLLKNLRLHSNGKEITDADILEWANAKVRNNGCKTRMYSFRDKSLSDGVFFLELLSSVQPRSVNWSLVTNGVTDEEKKMNATYVISIARKLGCSIFLLPEDIIEVNQKMMLTLTASIMYWTLKQPLHLNKPIGSPDSHNGSLLDDSTSDSSIE", "output": "Cross-links actin filaments (F-actin). Stabilizes and prevents F-actin depolymerization mediated by profilin. May regulate actin cytoarchitecture, cell cycle, cell division, cell elongation and cytoplasmic tractus."}]}
+{"id": "function_test_1022", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDVGELLSYQPNRGTKRPRDDEEEELKMRRRQAGTRERGRYREEEMTVVEEADDDKKRLLQIIDREGEEEEEEEEPLDESSVKKMILTFEKRSYKNQELRIKFPDNPEKFMESELDLNDIIQEMHVVATMPDLYHLLVELNAVQSLLGLLGHDNTDVSIAVVDLLQELTDIDTLHESEEGAEVLTDALVDGQVVALLVQDLERLDESVKEEADGVHNTLAIVENMAEFRPEMCTEAAQQGLLQWLLKRLKAKMPFDANKLYCSEVLAILLQDNDENRELLGELDGIDVLLQQLSVFKRHNPSTAEEQEMMENLFDSLCSCLMLSSNRERFLKGEGLQLMNLMLREKKISRSSALKVLDHAMIGPEGTDNCHKFVDILGLRTIFPLFMKSPRKIKKVGTTEKEHEEHVCSILASLLRNLRGQQRTRLLNKFTENDSEKVDRLMELHFKYLDAVQVADKKIEGEKHDMVRRGEIIDNDIEDEFYLRRLDAGLFVLQHICYIMAEICNANVPQIRQRVHQILNMRGSSIKIVRHIIKEYAENIGDGRSPEFRESEQKRILALLENF", "output": "Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated somatic hypermutation (SHM) and class-switch recombination (CSR), 2 processes resulting in the production of high-affinity, mutated isotype-switched antibodies."}]}
+{"id": "function_test_1023", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGAAKNIWALANAEDAANDAEQIPYSSFVVDTSLPLPLMIPRIIELCKDLFKNWGELDDSLFSVERVSGGITNLLLKVSVKEDTNKEVSVTVRLYGPNTEYVINREREILAIKYLSAAGFGAKLLGGFGNGMVQSFINARTLEPSDMREPKIAAQIARELGKFHKVDIPGSKEPQLWVDILKFYEKASTLTFEEPDKQKLFETISFEELHKEIIELREFTGLLNAPVVFAHNDLLSGNFMLNDEEEKLYLIDFEYGSYNYRGFDIGNHFNEYAGYDCDYSLYPSKEEQYHFIKHYLQPDKPDEVSIAEVESVFVETDAYKLASHLYWAIWAIIQARMSPIEFEYLGYFFLRYNEYKKQKPLTFSLVTSHLSASL", "output": "Involved in phospholipid biosynthesis. Catalyzes the first step in phosphatidylethanolamine biosynthesis (By similarity)."}]}
+{"id": "function_test_1024", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRTGCEPTRFGNEAKTIIHGDALAELKKIPAESVDLIFADPPYNIGKNFDGLIEAWKEDLFIDWLFEVIAECHRVLKKQGSMYIMNSTENMPFIDLQCRKLFTIKSRIVWSYDSSGVQAKKHYGSMYEPILMMVKDAKNYTFNGDAILVEAKTGSQRALIDYRKNPPQPYNHQKVPGNVWDFPRVRYLMDEYENHPTQKPEALLKRIILASSNPGDIVLDPFAGSFTTGAVAIASGRKFIGIEINSEYIKMGLRRLDVASHYSAEELAKVKKRKTGNLSKRSRLSEVDPDLITK", "output": "A beta subtype methylase, recognizes the double-stranded sequence 5'-ATGCAT-3' and methylates A-5."}]}
+{"id": "function_test_1025", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSRKDGVLALLVVVVWGLNFVVIKVGLHNMPPLMLAGLRFMLVAFPAIFFVARPKVPLNLLLGYGLTISFAQFAFLFCAINFGMPAGLASLVLQAQAFFTIMLGAFTFGERLHGKQLAGIALAIFGVLVLIEDSLNGQHVAMLGFMLTLAAAFSWACGNIFNKKIMSHSTRPAVMSLVIWSALIPIIPFFVASLILDGSATMIHSLVTIDMTTILSLMYLAFVATIVGYGIWGTLLGRYETWRVAPLSLLVPVVGLASAALLLDERLTGLQFLGAVLIMTGLYINVFGLRWRKAVKVGS", "output": "May be an export pump for cysteine and other metabolites of the cysteine pathway (such as N-acetyl-L-serine (NAS) and O-acetyl-L-serine (OAS)), and for other amino acids and their metabolites."}]}
+{"id": "function_test_1026", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPAYKYNRVFLIVMDSVGIGEAPDAADFNDEGAHTLGHIAEHMNGLHMPNMAKLGLGLIEDIKGVEKTEHPLAYYGKMQEASNGKDTMTGHWEIMGLYIDKPFKVFPEGFPDELLQELEKRSGRKIIGNKPASGTAILDELGQEHMETGALIVYTSADSVLQIAAHEEVVPLEELYRICETARELTLDPKYMVGRIIARPFVGEPGQFKRTPNRHDYALKPFDRTVMNELKDCGLDVISIGKISDIYDGEGITSSRRTVSNMDGMDKVIDTLGEDFTGLSFANLVDFDALFGHRRDPEGYGRALEEFDARLPEVFEKMREDDLLIITADHGNDPIHHGTDHTREYVPILAYSKKHKKAQMLPLADTFADIGATIADNFQTNKPKYGKSFLSLLQ", "output": "Phosphotransfer between the C1 and C5 carbon atoms of pentose."}]}
+{"id": "function_test_1027", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNKLSGGGGRRTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDVISTIGQAFELRFKQYLRNPPRLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPLGGVVDMRLREGALPGAARPTPPSAQTPSHLGATLPVGQPAGGDPEARRQMPPPPPSSGRELFDDPSYVNVQNLDKARQAGAGAGPPNPTINGSAPRDLFDMKPFEDALRMPPPPQSTAMAEQLRGEPWFHGKLSRREAEALLQVNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL", "output": "Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis (By similarity)."}]}
+{"id": "function_test_1028", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLDKIRFTVLLDRPFYQPGQTIQGHVVCEPHHPLEIDCVEGRLHGEIQYFQQLPPNHNRNGSPLPPSKTRVLIDEKAQLWKYQTVSEMLGLDVFYDENQNRHFSSESASASSSSLFTTAATFPIQIELPHFAPPSFYCPGSPVSIRFTLEIQLYNQGFKIASHEENLVVLNYESIKRQVTPKPVNFQKTFNFPKERSISLEMLLPTDVFTTTARLENCITICNRWKQSLKYVHLNIVRRISALNQNNEVIDTVKIDTTGVGLPSKTKIAVGETYSFRPTFNVPALPPNIHVNGLFKTEYSLKVTIGRAHNFVLASYEVPITIVTMDQSSRRSMQKEDILVDISASNNTLNNLPVDLLA", "output": "Involved in resistance to B.thuringiensis pore-forming toxin Cry5B downstream of the sek-1 and pmk-1 MAPK kinase pathway."}]}
+{"id": "function_test_1029", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTQAEKGEAENGKEKGGEKEKEQRGVKRPIVPALVPESLQEQIQSNFIVVIHPGSTTLRIGRATDTLPASVPHVIARRHKQQGQPLYKDSWLLREGLNKPESNEQRQNGLKMVDQAIWSKKMSNGTRRIPVSPEQARSYNKQMRPAILDHCSGNKWTNTSHHPEFLVGEEALYVNPLDCYNIHWPIRRGQLNIHPGPGGSLTAVLADIEVIWSHAIQKYLEIPLKDLKYYRCILLIPDIYNKQHVKELVNMILMKMGFSGIVVHQESVCATFGSGLSSTCIVDVGDQKTSVCCVEDGVSHRNTRLCLAYGGSDVSRCFYWLMQRAGFPYRECQLTNKMDCLLLQHLKETFCHLDQDISGLQDHEFQIRHPDSPALLYQFRLGDEKLQAPMALFYPATFGIVGQKMTTLQHRSQGDPEDPHDEQYLLATQSKQEQSAKATADRKSASKPIGFEGDLRGQSSDLPERLHSQEVDLGPSQGDCLMAGNDSEEALTALMSRKTAISLFEGKALGLDKAILHSIDCCSSDETKKKMYSSILVVGGGLMFHKAQEFLQHRILNKMPPSFRRIIENVDVITRPKDMDPRLIAWKGGAVLACLDTTQELWIYQREWQRFGVRMLRERAAFVW", "output": "Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize (By similarity).; "}]}
+{"id": "function_test_1030", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSKNKFLFTSESVSEGHPDKMCDQISDAVLDAHLAQDPHAKVACETVTKTGMIMLCGEITSKAVVDYQVLVRNVIKKIGYDDSSKGFDYKTCNVLVALEQQSPEIAAGVHVDKDIADVGAGDQGIMFGYATDETEEAMPLTLLLSHKLNYKLHELRRSGELEWVRPDSKTQVTIEYSSEGGACVPLRVHTVVISTQHSPDISLEDLRKELIEKVIKVVIPGNLIDNDTVYHLNPCGSFVVGGPMGDAGLTGRKIIVDTYGGWGAHGGGAFSGKDPTKVDRSAAYAARWVAKSLVKAGLCRRCLVQVSYAIGVAKPLSVMVFSFGTSALNEAELLKIVNDNFDLRPGMIIKNLDLKRAIYEPTAENGHFGHNDFPWEQARKLKIDKDLRAKSKGPALVDAIGIAH", "output": "Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate."}]}
+{"id": "function_test_1031", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLWQKPTAPEQAPAPPRPYQGVRVKEPVKELLRRKRGHASSGASVTPTAVVLPHQPLATYTTVGPSCLDMEVSASTVTEEGALCAGWLSQPAPAALQPLAPWTPYTEYVSHEAVSCPYSADMYVQPVCPSYTVVGPSSVLTYASQPLITNVTTRSAAAPTVGPPLEGPEHQAPLTYFPWPQPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPEPVLPDAEDPRRAIGSLTIDKLLLEEEDSDTYALNHTLSVEGF", "output": "Transcriptional coactivator that specifically associates with either POU2F1/OCT1 or POU2F2/OCT2. It boosts the POU2F1/OCT1 mediated promoter activity and to a lesser extent, that of POU2F2/OCT2. It recognizes the POU domains of POU2F1/OCT1 and POU2F2/OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers. Regulates IL6 expression in B cells as POU2F2/OCT2 coactivator."}]}
+{"id": "function_test_1032", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGSLSPLSFLWGLLLLQGVLRPLRGDPVFIPPFIRMSSPEVRASLVGGSEDVTVSLTPLQIKEGVLPVPTCGGLRNETGDWNLTVSPQANMLEVTVRWKRGLDWCSPDETASFSEAPCIVQTLLVSASHNASCLAHLLIQVEIYPNTSVTHNASENMTVIPNQVYQPLGPCPCDLTAKACDIRCCCDQDCQPELRELFERFCFSGVFGGYVSPPSHHRCAARTTHQTPDWFPFLCVQSPPSTSPFLGHFYHGAISPRHSPGFETHSHLDLRDFFADASYKQGDPIMTTNGYFTIPQASLAGQCLQDAPVAFLRNFHSVCTTDLEVQERDRLIPEDMRIRTTGGLVTPTVTYEEATDLDKLITSPDTILSAGSAPRNVTVEEHYVFRWQNNSISSLDITIIRAEINAHQRGTMTQRFTVKFLSPNSGGEKEFSGNPGYQLGKPVRALHTDGMNVTTLHLWQPAGRGLCTSAALRPVLFGEDASSGCLLEVGIKENCTQLRENVLQRLDLLIQATHVARRGNSDYGDLSDGWLEVIRVDAPDAGADLPLSSANGMCPEVPTHVTIRILTAEAGAVEGEAQREILAVETRFSTVTWQYQCGLTCEEDKADLLPLSASVKFINIPAQMPRPTRFQINFTEYDCTRNELCWPQLLYPLTQYYQGEPRPQCVAKGLMLLSLLMLAILLRHPWVGMCKAWSSASIQH", "output": "Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for hedgehog signaling transduction (By similarity)."}]}
+{"id": "function_test_1033", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIQQLPMVNVELMISNLRILVESKQFSSAEFLGNFVISVPNQQKTPHQNIISFSLFGDSLFGKNEFVRSLKYFKQSLDILFKVYNNPNNNNNNNNKQADFDNKQFEYELKYKISLCYIKINRNNLAISYLESIPFSSRGLDTHLTIARLYKDIGKEKSKECIISYKEVIKLCPLCLEAINSLKEMGENVDQVLIPSINKFQQKNNSFNSNNIIDLSWISLLSMSQYEMKRNQPEKSLILLKKVESKFSTNLYVLEKLALSYLYHDEPSIINTFNIFQKIRLLDPYYIGSMDIFCSLLKRRSLQFELNKVCNDLVASNPYCAETWTSVALFYFLKENVEKSLENVDRAISIKESHEFAHSLKGEILLSLDEPREALPSLERAFQLSKNILTARELVRCHLILNQMKEALVVAETINNLSPDYSKTMALLGMVLANQPEEREEARKILTKALTLSPHCTDTVLTLSKLNVVEGRFQEAIDILNSQLEYQETDLMHTEIAGVYLTKDYHEDAMIHYNSALEINPQYEPASRGIARLELIMKGIDPDQELDQENDDDDQEEGEGENDQEENDDDDNDDDDEYIS", "output": "Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle."}]}
+{"id": "function_test_1034", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLRLRVFDRHKRLWSVLQSTIRGNNISNHIPNTTCRSSAPPHLCARQRAFYSQNSPKTPNPGSSAGIKLRTRLVVTLLFGGGIIGTWWYVHQEKEKRIQMQRLEQLRKVALGQGDFHLLDHTGQRRTKRDFLGHWVLLYFGFTHCPDICPDELEKLTSVVHILDKDPSLPSVQPLFITVDPERDDVSAMARYVKDFHPRLVGLTGSAEEVKQAGRDFRVYASNGPKDEDGDYIVDHSIVIYLVNPDGLFIDYYNRMKNDTQIAESIRNHMKTFVRLFPD", "output": "Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2."}]}
+{"id": "function_test_1035", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSENILQDLEMVTCTAPVNIAVIKYWGKRDEDLILPVNASLSVTLHQDHLRTTTTIACSRSFHKDCIWLNGKEQDISHPRLQSCLLEIRRLAQRRKNTGDPASDVSNKVHICSVNNFPTAAGLASSAAGYACLVYTLSQLFNVEGELSGVARQGSGSACRSLYGGFVQWKLGEQSDGKDSIAEQVASELYWPELRVLILVVSAEQKSVGSTSGMHTSVETSHLLKYRADAVVPGRMEEMIRAIRLRDFPKFGELTMKDSNQFHAICLDTYPPIFYLNNISHQIISLVHRYNQYYGETRVAYTFDAGPNAVIYSLQDYLPEFVEVVRHFFPPEVNEEEFFKGLPVCPADLSEEMIRDINMKPTPNGIRYMISTKAGPGPRVVEDPNLHLLGADGLPKKSAV", "output": "Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis."}]}
+{"id": "function_test_1036", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSSTSQKHKDFVAEPMGEKSVMALAGIGEVLGKRLEEKGFDKAYVVLGQFLVLRKDEELFREWLKDTCGANTKQQGDCYSCLREWCDSFL", "output": "Non-specific DNA-binding protein that plays key roles in mitotic nuclear reassembly, chromatin organization, DNA damage response, gene expression and intrinsic immunity against foreign DNA. Contains two non-specific double-stranded DNA (dsDNA)-binding sites which promote DNA cross-bridging. Plays a key role in nuclear membrane reformation at the end of mitosis by driving formation of a single nucleus in a spindle-independent manner. Transiently cross-bridges anaphase chromosomes via its ability to bridge distant DNA sites, leading to the formation of a dense chromatin network at the chromosome ensemble surface that limits membranes to the surface. Also acts as a negative regulator of innate immune activation by restricting CGAS activity toward self-DNA upon acute loss of nuclear membrane integrity. Outcompetes CGAS for DNA-binding, thereby preventing CGAS activation and subsequent damaging autoinflammatory responses. Also involved in DNA damage response; acts by inhibiting the ADP-ribosyltransferase activity of PARP1. Involved in the recognition of exogenous dsDNA in the cytosol: associates with exogenous dsDNA immediately after its appearance in the cytosol at endosome breakdown and is required to avoid autophagy."}]}
+{"id": "function_test_1037", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEAWGQSPACSSSRKARTGPSLASVLNDLPSAATLRYRGPGVLPWGTLDEDDDEGGRSLQAFAETAQMESHPSRELPWPMQARRAHRKSQATGQLASGSESRAAYWTRQLSRTKGKMKEGFQTIQPWAWTLKKIGGQFGAGTESYFSLLRFLLFLNLVASVIEICMKLIPTWLEGAPPGPPGPNISSPCGSYIPHTHGLVAFPTQLFNLLSGEGYLEWSPLFYGFYPPRSNLAITYLCSVFAISVIYLLCILRRSVSGLKETLLAESDILTSYSHRVFSAWNFGLCGDVHVRLRQRIILYELQVDLEEAVVRRRAAEQTLSQRAKVWSMRALLNVLVLALLGAAFYGIYWATEYTLTLQETPLVRQTPLFKLLVDYLPSIFISLFNFVLPPVFKFIASLEGYTQSRQIVLILLRTVFLRLASLVFLLVSLWSQITCGGNMEAEGCKACGYNYKEIPCWETRLGQEMYKLVLFDLLMGLLVTLLVQFPRKILCGLCPGALGRLSGTLEFQVPDEVLGLIYAQTVVWVGSFFCPLLPLINTAKFLILFCLKKITLFSIYSPASRTFRASTANFFFPLVLLVGLAISAVPVLYSIFLIPPSKLCGPFRGKLSIWAQIPEAIESLPQTAQNFLYFLGTQAFTVPLLILSSILMMYTVALANCYGRLISELKRQIETEVQNKVFLAQRAVALSSRNGTS", "output": "Probable ion channel."}]}
+{"id": "function_test_1038", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTERGAMVVSSSTCYVPFRCPQARKDFAFVEPSKKLNPNRVLIKPPVYTYSPALTAAKCNIFDYAETGENLVGDKQFVRWFREAWPYLWAHRSCTFVVTISGDVLDGPYCDLVLKDIAFLHHLGIKFVLVPGTQVQIDQLLAERGREPTYVGRYRVTDSASLQAAKEAAGAISVMIEAKLSPGPSIYNIRRHGDSSRLHETGVRVDTGNFFAAKRRGVVDGVDFGATGLVKKIDVDRIRERLDSGSVVLLRNLGHSSTGEVLNCNTYEVATACALAIGADKLICIMDGPVLDENGHLVRFLTLQEADTLVRKRAQQSEIAANYVKAVGDGGISSFPEPLGYNGMVTTPNNHIGRPIWEKLSPTFQNGVGFDNGNGLWSGEQGFAIGGEERISRLNGYLSELAAAAFVCRGGVKRVHLLDGTISGVLLLELFKRDGMGTMVASDVYEGNREAKVEDLAGIRQIIKPLEESGALVRRTDEELLRALDSFVVVEREGHIIACAALFPFFEEKCGEVAAIAVASDCRGQGQGDKLLDYIEKKASALGLEMLFLLTTRTADWFVRRGFQECPIEMIPEARRERINLSRRSKYYMKKLLPDRSGISVVRTFQYDS", "output": "N-acetylglutamate synthase involved in arginine biosynthesis."}]}
+{"id": "function_test_1039", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLSMLWFLLSLLSLLLLPCLRPCFPAKGSLKNKKKIDKGTYVVGEEETPKELQRELMPRHVAVIMDGNRRWAKQTGLLTSQGYEAGAKRLLEFADLCFKLGINTVSAFAFSTENWGRHKIEVKCLMYLFQRYLKSKIQFFQSKEIRVSVIGNLAKIPESLLRTVHELEEATKSYKKKHLILAIDYSGRFDILGACKNIVKKSEQGLIREEDVDETLFERELQTRCTEFPSPDLLIRTSGEQRISNFFLWQLAYTEFFFSPVLWPDFDKQKFIEALVSYQRRDRRFGSRL", "output": "Catalyzes cis-prenyl chain elongation to produce the polyprenyl backbone of dolichol, a glycosyl carrier-lipid required for the biosynthesis of several classes of glycoprotein."}]}
+{"id": "function_test_1040", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MALSSRAHAFSVEALMGRPSKRKAQDPREEMQPELQEEQFVEEGEEILRSPSRDSQQPEKRLKAESSKTVFSCSDESNSQESLQEESVIQVELQGSDLWKRFHDIGTEMIITKAGRRMFPSVRIKVKGMDPVKQYYVILDVVPVDSKRYRYVYHSSQWMVAGNTDHSCITPRFYVHPDSPCSGENWMRQIISFDRVKLTNNEMDDKGHIILQSMHKYNPRVHVVEQDSRIDLSLIESFPTEGVKTFSFKETEFTTVTAYQNQQITKLKIDRNPFAKGFRDPGRNRGVLDGFLETYPWMPSFSMDFKTFVTDTQSGSSGSSPVTSSGGAPSPLNSLLSPSCSPPMVYIPPSSFGMTYPDAYLHSVNIPFCYRICPTNNWRSQPFVLPTPERLPSFIIPQTLPPLMMEVPVVSSRGIINPNSGLHEDCNGQCLQASHSANQMLYGLQNPGNIFHPNAIAQEAISYPFHPPNGCYRYTISMPPRLENVASHLSENGTSQISFTEGSCDHSHWYPAINHYL", "output": "Probable transcriptional regulator involved in developmental processes. This is major determinant crucial to palatogenesis."}]}
+{"id": "function_test_1041", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTTLNTGSARISIMNGSSVASTSPSVKCKEDQGLNGHEEKENPFAEYMWMENEEDFNRQVEEELQEQDFLDRCFQEMLDEEDQDWFIPARDLPQAVGHLQQQLNGLSVGDSHESEDILSKSNLNPDAKEFVPGVKY", "output": "Inhibits translation of capped and polyadenylated mRNAs by displacing PABPC1 from the poly(A) tail."}]}
+{"id": "function_test_1042", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGLWYRMLENQDLEEVITVRVQDPRVQNEGSWNSYVDYKIFLHTNSKAFTAKTSCVRRRYREFVWLRKQLQRNAGLVPVPELPGKSTFFGGSDEFIEKRRQGLQHFLEKVLQSVVLLSDSQLHLFLQSQLSVPEIEACVQGRGAMTVSDAILSYAMSNCGWAQEERQSTSHLAKGDQLNSCCFLPRSGRRSSPSPPLSEEKEQLETWAPVMDSEGPSSESPTLLPSSSLPACWDPARPEEGLSVSQPARRAVAADQAGPMEPTQLDTAWDK", "output": "Phosphoinositide-binding protein involved in protein sorting and membrane trafficking in endosomes."}]}
+{"id": "function_test_1043", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPNPGSTSSPGSIPEEIRNLLADVETFVADTLKGENLSKKAKEKRDSLIKKIKDVKSVYPQEFQDKGDAEEGDEYDDPFAGPPDTISLASERYDKDDDGPSDGNQFPPIAAQDLSFVIKAGYLEKRRKDHSFLGFEWQKRWCALSKTVFYYYGSDKDKQQKGEFAIEGYDVRMNNTLRKDAKKDCCFEICAPDKRIYQFTAASPKDAEEWVQQLKFILQDMGSDVIPEDEDEKGDLYDDVDHPVPVSSPQRSQPIDDEIYEELPEEEEDTASVKMDEQGKGSRDSVQHPSGDKSTDYANFYQGLWDCTGSLSDELSFKRGDVIYILSKEYNRYGWWVGEMQGAIGLVPKAYLMEMYDI", "output": "May be involved in B-cell and macrophage adhesion processes. In B-cells, may act by coupling the B-cell receptor (BCR) to integrin activation. May play a role in src signaling pathway (By similarity)."}]}
+{"id": "function_test_1044", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLRYPYFYRTYNRLFSHFVDSGASNLDVCPHTIHTAVALHTESKAVEGTALCGPQKVYSSEEKELEAMAKLHIPVMVDQVVHCLAPQKGQVFLDMTFGSGGHTRAILQKEPDVMVYALDRDPVAYAIAEQLSRLYPTQIQALLGQFSQAEALLMKAGVQPGTIDGILMDLGCSSMQLDAPERGFSLRKDGPLDMRMDGDRYPDTPTASDVVNALDQQALASILRAYGEEKHAKKIASAIIQARSTYPISRTQQLASIVAGAFPPSAVYARKDLLQRSTHIATKTFQALRIFVNNELNELYAGLRTAEKFLKTGGRLVALSFHSLEDRIVKRFLLGISMTERFNLSIRQKVKQTSQLDSDQETEERHSVRAPLKWELIHKKVLTPEDQDVQDNPRGRSAKLRAAIKL", "output": "N4-methylcytidine (m4C) methyltransferase responsible for the methylation of position C839 in mitochondrial 12S rRNA. Involved in the stabilization of 12S rRNA folding, therefore facilitating the assembly of the mitochondrial small ribosomal subunits."}]}
+{"id": "function_test_1045", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MESEIASEFLPFCRIYKDGRVERLIGTDTIPASLDPTYDVVSKDVIYSPENNLSVRLFLPHKSTKLTAGNKLPLLIYIHGGAWIIESPFSPLYHNYLTEVVKSANCLAVSVQYRRAPEDPVPAAYEDVWSAIQWIFAHSNGSGPVDWINKHADFGKVFLGGDSAGGNISHHMAMKAGKEKKLDLKIKGIAVVHPAFWGTDPVDEYDVQDKETRSGIAEIWEKIASPNSVNGTDDPLFNVNGSGSDFSGLGCDKVLVAVAGKDVFVRQGLAYAAKLEKCEWEGTVEVVEEEGEDHVFHLQNPKSDKALKFLKKFVEFIIG", "output": "Carboxylesterase acting on esters with varying acyl chain length."}]}
+{"id": "function_test_1046", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAHLKLDTLHVQRSPRGSRRSSPSSGRSSACSSGSISPVPIIPIISISHDGDESESESEIETEPARLFQRRMSTKCTNNLAAIIKEGFLLKHTWSFQRWRRRYFRLKRNMLFYAKDEKCDVFDDIDLSDLCYFECGIKNVNHSFQIITPTRSLVLCAESRREMEDWLGSLKTATAPQRPRGDSFLIEQHDILSNHHHWYATSHARPTYCNVCRDALSGVTSHGLSCEVCKCKVHKRCAAKSIANCKWTTLASVGKDIIEQADGIIMPHQWMEGNLPVSSMCAVCKKTCGSVLRLQDWRCLWCRATVHVACRPQMAVACPIGPAKLSVVPPTSVHSISTDDAWDVASPKGNFSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLISTGPSLGLRLFRHFEMFRILVCSGDGSVGWVLSEIDRFNMHKQCQVAVMPLGTGNDLARVLGWGSSCDDDTHLPQILERYESASTKMLDRWSIMVFEKAIPVPKTPKMSISTEQEAMLTGMVTSANHHLRFIVETNDTQTLIRSTRNLCDTVDDLVCRISEHHKDDEQLAVKCDILRQKLNMLLDALQEEEIGAHSGDDLIATIRSLIARSIPVTPGSNAYLLNPNISIEKTEKDQINTKERRNSRSLRSSEKEALQCRANSVKRAIYNVVEHSEPGRPKRYQRKLSITPFEALKLPTASGESTPCTSPLPIIPPINIISPTMETSRLTCISPLPDTRRDSVDENFFNSINLPAPRQFADSRRSSGVEVIQEIEEGANGETVYRKSRMSLTGGANIDDAGNRLSPCSDAGENTPTERKVDFLRVPIHTGEPIVDPLCDYRPHEVFERTYYMTREMDKGKEKDKEKDKPVEIDKEKDTCVEKEGSMPAEKLVHTCNLQVPGVVVTPNPQNVYSSASITIIDTDAQTTTEQSSSDDLGGEASDVLSAISNEECSVASEIFDKQDAGQTVGDIIQNMDASNFTHIDSPETSDETEAMPGESIMDDISSVLGHDITYALQDNTLTDDTTTLCSEHAGPPKPPRKKSLSALSRTQAHPRRRNSSPPRMARLARMDSDDNPQQFGFENIVFEIDNRCDDQKMREPPRYCSLAQFVEGNDIARQSFKQLMLEQHRGGDNDSDYPEHEQTPTNKGANLLATTSEDELSTQTAIKIEIQDIDATVRNLNSSMKPNTILTTSTSPTKKSGHGQDVKRITFDESCKKESFDDVNPNYPQISVVVRPPTPLRGDCIKPTVSLLPVSSGGAMTVSMTCSGMLGVRAMNASEIRRHSSHAPGLAVREFDKDKDRRHSGFNPNQLTLDPEHARFLSSSPAASRRISCGSLFKPNEALPNLQTLKGSKSSLFMGSTLFGFDHLASAEKDKEEKSGKDKEKTPTDETNRKLPIINPLVRLPNWPNLANGGGFISKCLLANADTLCAAVSPLMDPDETLLAGYHEKCVMNNYFGIGIDAKISLDFHNKREEHPEKCRSRARNYMWYGVLGSKQLLQKTCKNLEQRVQLECDGQRIPLPELQGIVILNIPSFMGGTNFWGSSKKDDIFLPPSFDDRVLEVVAVFGSVQMAASRLINLQHHRIAQCQSVQINILGDEEIPIQVDGEAWLQPPGMIRILHKNRVQMLCRNRSLELSLKSWQEKQRQHSISIQRDASSTASEHANSTDEVISERECYVLLNFIEAVSSLVKWVKFLIISHPALQHDLYEVACRASEALESIHPQGKLLEGPSLRTKLVEVIDSSRQLYDDACTLLRDRGHSLILREDLETKLSAALANMEMELKKCSVQKCIDGKLRAYFNVLAPNEESDGRRKSRPFWVRLRSGSTAGQQAFKPPLTNTREAANNWSVNEVVTWLETMQLSEYVDSFLKNDIRGKELLTLGRRDLKDLGVVKVGHVKRILQAIKDLSEN", "output": "Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA)."}]}
+{"id": "function_test_1047", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAPEMDQFYRSTMAIYKSILEQFNPALENLVYLGNNYLRAFHALSEAAEVYFNAIQKIGEQALQSSTSQILGEILVQMSDTQRHLNSDLEVVVQTFHGDLLQHMEKNTKLDMQFIKDSRQHYEMEYRHRAANLEKSMSQLWRMERKRDKNAREMKESVNRLHAQMQAFVSESQRAAELEEKRRYRFLAEKHLLLSNTFLQFFGRARGMLQNRVLLWKEQSEASRSPSRAHSPGLLGPVLGPPYPSGRLTPTRLDMPQRALGEFGSPRSRHGSGSYGPEPAEARSASQLEPDHRRSLPRTPSASSLYSSSTQRSRSNSFGERPGGGGGGGGARRVRALVSHSEGANHTLLRFSAGDVVEVLVPEAQNGWLYGKLEGSSSSGWFPEAYVKPLDELPVNPMNPLNPVTSMNPRSPVNELPSRLRSYPLRGSHSLDDLLDRPGNSTASSDYWDGQSRSRTPSHIPSRTPSPAPTPLPSSRRSSMGSMGVASDVKKLASWEQQPPELFPRGTNPFATVKLRPTVTNDRSAPLIR", "output": "Phosphoinositides-binding protein that induces the formation of planar or gently curved membrane structures. Binds to phosphoinositides, including to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) headgroups. There seems to be no clear preference for a specific phosphoinositide (By similarity)."}]}
+{"id": "function_test_1048", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNALHQKCAVCGRFTTEFNYSVLSCNSCKIFFRRLIVRTVPIKKCFRGERCFEKTPYIFKCTSCRFQKCLYVGMTLPSYLLVLEQNKEQRLAITIDCVRNTHNKRMDSLFNFFVTEMNPNVDDIVELNKITYTKRDEHIRMDFQTWAFHSCVTTIDFMKQFPFVNLLRSTDQMILLKESYVKLGALISATRAYSSKKQCISFPDGTDCLPKTQWTVPKISPNLENRIRCRVIDKLRELNIQNDEFYLLSVLLFCNPAITNLSENGQLLLTSYQKMYSSALLYYCLLTYQKSGPSRFSELLGLFTLLGQHYDDIIHYYVLMQLNQSEVELKKLVKDGIEAAYKS", "output": "Orphan nuclear receptor."}]}
+{"id": "function_test_1049", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLKSIKSSGVTAVLDHDGFNKRIRVVRYDGAIEKALPDIVAAAKEENAEKIIVYAKQHDEPILAKQLFAPEGYLKGYYLGHSACVMVRYLSESRRQTDSYTEEQEIIEAIYRTAPRLRNDSTPVFTMRKAETNDMYQLSMLYKKVFRTYPTPVFDPAYIEKTMNANTVYYIMLDHDRLISAASAEINPELGHAEITDCAVLPEYRGHSLTSFLIEALEKEMAGEDIVHVFSLARASSFGMNAVLYHSGYQYGGRLINNCFIAEGLENMNIWCKQL", "output": "In vitro, is able to catalyze the acetylation of beta-lysine to N6-acetyl-beta-lysine, an archaeal osmolyte produced by methanogenic archaea. Its physiological function has not yet been elucidated."}]}
+{"id": "function_test_1050", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGSKYPRSLRCCLPLWAFGLQVTFILLFYFLIGQDPIQADHKFMAIYQVIQDLTLVAALGFGFLSSSFRRHGWSSVAFSFFMLALGVQGTILLDYFLNWVLDWNMIKNPFSPFLSIQRATISTLPLLISAGAVLGKVNLVQLAVMVLVEAMTFGAIRVADKKVFRIEDHIIMMYGHVFGAYFGLTVAWWLSKSLPRRRHENAQTEKVQMTTSSSLFAMLGTLFLWIFWPSINSALLEGTKKKNAVFNTYYALAVSTVTATSMSALSHPKGKINMVHIHNAVLAGGVAVGAPSCLISSPWIAMVLGLTAGLISIWGAKCPQVCLSDLLLNPSGIHYTFGLPGLLGALTYYCLHIIAESRPSNLWIVTQTITDVGALSFAMAMGMVTGLLTGCLLSVKVWRAPHAVKYFDDQAFWEFPHLAVEF", "output": "May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane."}]}
+{"id": "function_test_1051", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDALEKGAATSGPAPRGRPSRGRPPKLQRSRGAGRGLEKPPHLAALVLARGGSKGIPLKNIKRLAGVPLIGWVLRAALDAGVFQSVWVSTDHDEIENVAKQFGAQVHRRSSETSKDSSTSLDAIVEFLNYHNEVDIVGNIQATSPCLHPTDLQKVAEMIREEGYDSVFSVVRRHQFRWSEIQKGVREVTEPLNLNPAKRPRRQDWDGELYENGSFYFAKRHLIEMGYLQGGKMAYYEMRAEHSVDIDVDIDWPIAEQRVLRFGYFGKEKLKEIKLLVCNIDGCLTNGHIYVSGDQKEIISYDVKDAIGISLLKKSGIEVRLISERACSKQTLSALKLDCKTEVSVSDKLATVDEWRKEMGLCWKEVAYLGNEVSDEECLKRVGLSAVPADACSRAQKAVGYICKCSGGRGAIREFAEHIFLLLEKVNNSCQK", "output": "Catalyzes the activation of N-acetylneuraminic acid (NeuNAc) to cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-NeuNAc), a substrate required for the addition of sialic acid. Has some activity toward NeuNAc, N-glycolylneuraminic acid (Neu5Gc) or 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN) (By similarity)."}]}
+{"id": "function_test_1052", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEDEEEEARALLPGGSDEAGRETRAPPAASGALQALCDPSHLAHRLVVLLLMCFLGFGSYFCYDNPAALQIQVKRDMQVNTTKFMLLYAWYSWPNVVLCFFGGFLIDRVFGIRWGTIIFSCFVCIGQVVFALGGIFNAFWLMELGRFVFGIGGESLAVAQNTYAVSWFKGKELNLVFGLQLSMARIGSTVNMNLMGWLYSKVEASLGSAGHTTLGVTLMIGGITCILSLVCALALAYLDQRAERILHKEQGKTGEVIKLTDVKDFSLPLWLIFIICVCYYVAIFPFIGLVKVFFTEKFGFSSQAASAINSVVYVISAPMSPIFGLLVDKTGKNIIWVLCAVVTTLASHIMLAFTLWNPWIAMCLLGLSYSLLACALWPMVAFVVPEHQLGTAYGFMQSIQNLGLAVISIIAGMILDTRGYLFLEVFFIACVSLSLLSVVLLYMVNHAQGGNLNYSAKKREEMKLSHEE", "output": "Lysosomal transporter which is essential for liver homeostasis. Required to maintain stability and lysosomal localization of GLMP."}]}
+{"id": "function_test_1053", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MASAVWGNAPWWSPPPPAPARPLTDIDFCSGAQLQELTQLIQELGVQESWNDGPKPGPDLLQAKDFVFSLLSLIHRRDPRFPPQTELLLLRGGIREGSLDLGPAPLGPYTRGPHYDAGFTLLVPVFSLDGTGQELQLDMRSCYAWLCLPEQVRGTSVREAWQDCLGPPVPGGRDWIHPTDSREGPRDPQSSVDQPHSDIIEPEAHESLEKSPSNVSVPESPQQNLTDIGFPSLSEETNDDVTKAADVSPGPQPSEAREAWPTLCPAQVAAWFFASLAAVAESLFPVPGAPRLVHAARHAGFTTILLATPGPPRRLLLFDLIPVVSVAGWPQGARSHSWAGPLASESSSFYLVPGGGGQTERPGASGWQLCFARQELALKARIPTPLLQAHAAAQALLRPLVAGTRAAAPYLLRTLLYWACERLPALYLARPENAGACCLGLLDELGRVLEARTLPHYFLSGQKLRAGDGASSLLGALALLRGDPARALRAAVEEAKAARKGGGLAGVGAGSH", "output": "Selectively involved in CSF2 deprivation-induced apoptosis via a mitochondria-dependent pathway."}]}
+{"id": "function_test_1054", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLRISSSSSMALKFSQILFIVLWLSLFFLLLHHLYSLNFRRLYSLNAVEPSLLKQHYRSYRLVSRKVLSDRFDFTPFHSRDNSRHNHRSGEQYDGDEIDPRYGVEKRRVPSGPNPLHH", "output": "[CLE12p]: Extracellular signal peptide that regulates cell fate. Represses root apical meristem maintenance."}]}
+{"id": "function_test_1055", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSRPVRNRKVVDYSQFQESDDADEDYGRDSGPPAKKIRSSPREAKNKRRSGKNSQEDSEDSEEKDVKTKKDDSHSAEDSEDEKEDHKNVRQQRQAASKAASKQREMLMEDVGSEEEQEEEDEAPFQEKDSGSDEDFLVEDDDDSDYGSSKKKNKKMVKKSKPERKEKKMPKPRLKATVTPSPVKGKGKVGRPTASKASKEKTPSPKEEDEEPESPLEKKASSSPPPEKSGDEGSEDDAQSGED", "output": "Chromatin-associated protein involved in DNA repair by promoting homologous recombination (HR). Binds double-stranded DNA (dsDNA) and secondary DNA structures, such as D-loop structures, but with less affinity than RAD51AP1."}]}
+{"id": "function_test_1056", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEKLDRYLQEHFDVPAKNPSEEAQRRWRQAVGTIVKNRRRRFRWVPDLDRRSLDKAKVRSTQEKIRVALYVQQAALIFSDDELALITSKHDSKALKMHGGVDGISKKVRSSFDHGICASDLDTRQNIYGVNRYAEKPSRSFWMFVWDAFQDMTLIILMVCALLSVAVGLATEGWPKGMYDGLGIILSIFLVVMVTAVSDYKQSLQFKELDNEKKKIFIHVTRDGRRQKISIYDLVVGDIVHLSIGDQVPADGLYIHGYSLLIDESSLSGESDPVYVSQDKPFILAGTKVQDGSAKMIVTAVGMRTEWGKLMSTLSEGGEDETPLQVKLNGVATVIGKIGLVFAILTFLVLLVRFLIDKGMTVGLLKWYSTDALTIVNYFATAVTIIVVAVPEGLPLAVTLSLAFAMKKLMNDKALVRHLSACETMGSAGTICTDKTGTLTTNYMVVDKIWISEVSKSVTSNTISGELNSVVSSRTLSLLLQGIFENTSAEVVKEKDGKQTVLGTPTERAILEFGLGLEGVHDAEYSACTKVKVEPFNSVKKKMAVLISLPSGTSRWFCKGASEIILQMCDMMVDGDGNAIPLSEAQRKNILDTINSFASDALRTLCLAYKEVDDDIDDNADSPTSGFTLIAIFGIKDPVRPGVKDAVKTCMSAGITVRMVTGDNINTAKAIAKECGILTEDGVAIEGPEFHSKSPEEMRDLIPNIQVMARSLPLDKHTLVTNLRGMFDEVVSVTGDGTNDAPALHEADIGLAMGIAGTEVAKESADVIVLDDNFTTIINVARWGRAVYINIQKFVQFQLTVNIVALVINFVSACITGSAPLTAVQLLWVNMIMDTLGALALATEPPNDEMMKRPPVRKGESFITKVMWRNIMGQSLYQLFVLGALMFGGESLLNIKGADSKSIINTLIFNSFVFCQVFNEINSREMQKINVFRGIISNWIFIAVIAATVAFQVVIIEFLGTFASTVPLNWQHWLLSVGLGSISLIVGVILKCIPVGSGETSATPNGYRPLANGPDDI", "output": "This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol out of the cell, into the endoplasmic reticulum, or into organelles."}]}
+{"id": "function_test_1057", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTMDGDSSTTDASQLGISADYIGGSHYVIQPHDDTEDSMNDHEDTNGSKESFREQDIYLPIANVARIMKNAIPQTGKIAKDAKECVQECVSEFISFITSEASERCHQEKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFREAMKGEKGIGGAVTATDGLSEELTDEAFTNQLPAGLITADGQQQNVMVYTTSYQQISGVQQIQFS", "output": "Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors (By similarity)."}]}
+{"id": "function_test_1058", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLPRPYIFSHNDGPSSHLFQHVLPHNVSQQQRIEAHLNSTNNFIGPPMNAPRFIPTYQWTPVELSDVACSPNGPMGNNRKRRIQDNSDINLKRQRFSCPSPHNQSARNSNFTSQPVTRPVTGREVTCPTCSSATFIPGGCVPSLGETCHQNAFSPSSVKDKLSQQILNLFFACEQQSDDLEKKESCRAALQTDIQKIFPCAKVFLGGSSLNGFGSRSSDADLCLVIEEGPVNHRKDAVYVLSLVRKLLYKLSYIEKPQLIRAKVPIVKFRDRISGVEFDLNFNNTVGIRNTFLLRTYAFVEKRVRPLVLVIKKWANHHCINDASRGTLSSYTLVLMVLHYLQTLPEPVIPCLQRDYPTCFDPKMDIHLVPSGPSDIPAFVSRNQSSLGDLFLGFLRYYATVFKWDKQVISVRMARTLPKSNCKEWKDKFICVEEPFNRTNTARAVHERMKFEAIKAAFIESHRLLQLRKDLNFILPKSKQMARPQTAPR", "output": "Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. May not play a role in replication-dependent histone mRNA degradation (By similarity)."}]}
+{"id": "function_test_1059", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDNLKSKNKGNGGGDHDNYGNDNDKFNVLSDKFDALLALKNPQLVSLPFPKIKPLDNIHKARILLPPSDENYVQIKKPPTQPINNINITSLNNNNSSTTTNTSPPIESTPTTTTTTTTTTTTSTTSTNSIASIVETTTTTTTIRKKNTNEDHKILKNISNKFTDGPLSLLKRALESKSKIKVMIRGTNCIRGYCRGYIIAFDKHMNIILRDVEEEYDLLKSLPSTRNQNQPIQPKIKRYYGQLFIKGDTVVSVILID", "output": "Required for pre-mRNA splicing. Required for snRNP biogenesis (By similarity)."}]}
+{"id": "function_test_1060", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGANQLVVLNVYDMYWMNEYTSSIGIGVFHSGIEVYGREFAYGGHPYPFSGIFEISPGNAAELGETFKFKEAVVLGSTDFLEDDIEKIVEELGKEYKGNAYHLMHKNCNHFSSALSEILCGKEIPRWINRLAYFSSCIPFLQSCLPKEWLTPAALQSSVSQELQDELEEAEDAAASTAMASAAAGGRTGRHTKL", "output": "Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization."}]}
+{"id": "function_test_1061", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSVPPGSIIVSDWHRCPDSREFFSKILHKKRRRKFGLLEAPMMPPQMNVDLVRYKVFLSGKTGVGKSALAARLAGLDLPKMHYETTGIETTVVFWPVRLKESGRVLFFRFELWDCGESAMRRFDHMLLSCKEKVDAILFLFSFTDRGSFDDLTNQISRITEPSDRVVKLVVGTKFDLFMHTDVTESDVTHFQEVWGLPVFRVGGDVSAGLGEVAPLLNALAENLWHQDCMAASSVSISPQAALRETSSEIIV", "output": "Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells (By similarity)."}]}
+{"id": "function_test_1062", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKTEDDEMEYEASKEETVSEDKDFDDGIDYRTVIKENIFTMWYKTSLHGEFATLNCVITPKDQNLLQHIFDEDIQTSEAPQTVVLQGAAGIGKTTLLKKAVLEWADGNLYQQFTHVFYLNGKEISQVKEKSFAQLISKHWPSSEGPIEQVLSKPSSLLFIIDSFDELDFSFEEPQFALCKDWTQISPVSFLISSLLRKVMLPESYLLVATRSTAWKRLVPLLQKPQRVKLSGLSKNARMDYIHHLLKDKAWATSAIYSLRMNWRLFHMCHVCHMCQMICAVLKGQVEKGGRVEETCKTSTALFTYYICSLFPRIPVGCVTLPNETLLRSLCKAAVEGIWTMKHVLYQQNLRKHELTREDILLFLDAKVLQQDTEYENCYMFTHLHVQEFFAALFYLLRENLEEQDYPSEPFENLYLLLESNHIHDPHLEQMKCFLFGLLNKDRVRQLEETFNLTISMEVREELLACLEGLEKDDSSLSQLRFQDLLHCIYETQDQEFITQALMYFQKIIVRVDEEPQLRIYSFCLKHCHTLKTMRLTARADLKNMLDTAEMCLEGAAVQVIHYWQDLFSVLHTNESLIEMDLYESRLDESLMKILNEELSHPKCKLQKLIFRAVDFLNGCQDFTFLASNKKVTHLDLKETDLGVNGLKTLCEALKCKGCKLRVLRLASCDLNVARCQKLSNALQTNRSLVFLNLSLNNLSNDGVKSLCEVLENPNSSLERLALASCGLTKAGCKVLSSALTKSKRLTHLCLSDNVLEDEGIKLLSHTLKHPQCTLQSLVLRSCSFTPIGSEHLSTALLHNRSLVHLDLGQNKLADNGVKLLCHSLQQPHCNLQELELMSCVLTSKACGDLASVLVNNSNLWSLDLGHNILDDAGLNILCDALRNPNCHVQRLGLENCGLTPGCCQDLLGILSNNKSVIQMNLMKNALDHESIKNLCKVLRSPTCKMEFLALDKKEILKKKIKKFLVDVRINNPHLVIGPECPNTESGCWWNYF", "output": "May be involved in inflammation and spermatogenesis."}]}
+{"id": "function_test_1063", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MHNASYWGPERANTSCPAPAPTLGCPNASGPAPPLPPPLAVAVPVVYAVICAVGLAGNSAVLFVLLRAPRRKTVTNLFILNLAVADELFTLVPPVNIADFLLRRWPFGELLCKLVVAVDQYNTFSSLYFLTVMSADRYLVVLATAESRRVAGRTYGAARAVSLAVWGVATLVVLPFAVFARLDEEQGRRQCVLVFPQPEALWWRASRLYTLVLGFAIPVSTICVLYTSLLCRLRAIRLDSHAKALDRAKKRVTVLVVAILAVCLLVWTPYHLSTVVALTTDLPQTPLVIAVSYFITSLSYANSCLNPFLYAFLDDSFRRSLRQLLACRTTS", "output": "Interacts specifically with a number of opioid ligands. Receptor for neuropeptides B and W, which may be involved in neuroendocrine system regulation, food intake and the organization of other signals (By similarity)."}]}
+{"id": "function_test_1064", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDVLRPQIVTFDGRNYRKNPIQEKQYQHEEDEDFYPDSMEYSDEPCGAYEVAQTPHGFRATVSAPSLLYKHIVGKRGDTKKKIEVETKTSINIPKHGHEGEIVITGQHRNGVVSARTRIDVLLDTFRRRQPFTHFLSFFLNEVEVQERFLMFQEEVLRKCSKDRGVDSTIFQNPKKLHLTIGMLVLLSEQEIQQTCEILQRCKEEFINDISGGRPLEVEMAGIEYMNDDPAMVDVLYAKVHMKDGSNRLQELVDRVLERFQSLGLIVKEWTSVKLHATVMNTLLRKDPNAEGRYNLYTADGKYIFKERESFDGRNILKTFENFYFGSLRLNSIHISQRFTVDSFGNYASCGHVDFS", "output": "Plays a role in DNA damage repair as component of the ASCC complex. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation. In cells responding to gastrin-activated paracrine signals, it is involved in the induction of SERPINB2 expression by gastrin. May also play a role in the development of neuromuscular junction."}]}
+{"id": "function_test_1065", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MVKETVTVAKTCSHCGHNGHNARTCLNGVNKASVKLFGVNISSDPIRPPEVTALRKSLSLGNLDALLANDESNGSGDPIAAVDDTGYHSDGQIHSKKGKTAHEKKKGKPWTEEEHRNFLIGLNKLGKGDWRGIAKSFVSTRTPTQVASHAQKYFIRLNVNDKRKRRASLFDISLEDQKEKERNSQDASTKTPPKQPITGIQQPVVQGHTQTEISNRFQNLSMEYMPIYQPIPPYYNFPPIMYHPNYPMYYANPQVPVRFVHPSGIPVPRHIPIGLPLSQPSEASNMTNKDGLDLHIGLPPQATGASDLTGHGVIHVK", "output": "Probable transcription factor involved in somatic embryogenesis. Acts as positive regulator of BHLH109."}]}
+{"id": "function_test_1066", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSLSSRATLVVLCCLFMLIPSFTTAATEQGLHARSRCESYSFNNGKSFRSCTDLLVLNSYLHFNYAQETGVLEIAYHHSNLESSSWISWAINPTSKGMVGAQALVAYRNSTSGVMRAYTSSINSYSPMLQESPLSLRVTQVSAEYSNGEMMIFATLVLPPNTTVVNHLWQDGPLKEGDRLGMHAMSGDNLKSMASLDLLSGQVTTTKSVNRNMLLVKQIHAIVNALSWGILMPIGVMAARYMKNYEVLDPTWFYIHVVCQTTGYFSGLIGGLGTAIYMARHTGMRTTLHTVIGLLLFALGFLQILSLKARPNKDHKYRKYWNWYHHTMGYIVIVLSIYNIYKGLSILQPGSIWKIAYTTIICCIAAFAVVMEILQFKKRWARLFFKKSKDVEADQPTVSVDVIGETEKAERKKASGGIEIQIENYNITKNFMIPSVFVISYPHTSPPLLAFHSYHHPSTSIAATAA", "output": "May act as a catecholamine-responsive trans-membrane electron transporter."}]}
+{"id": "function_test_1067", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAVGILEVSLISGKGLKRSDFLGKIDPYVEIQYKGQTRKSSVAKEDGGRNPTWNDKLKWRAEFPGSGADYKLIVKVMDHDTFSSDDFIGEATVHVKELLEMGVEKGTAELRPTKYNIVDSDLSFVGELLIGVSYSLLQDRGMDGEQFGGWKHSQVD", "output": "Binds to both sense and antisense RNA . Can also bind sheared DNA and dodecamer DNA with a low affinity . Interacts with mesophyll plasmodesmata to mediate its own cell-to-cell transport and potentiate RNA trafficking (By similarity). May play a role in plant defense signaling (By similarity)."}]}
+{"id": "function_test_1068", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIPASMEEAHQLESRSDDLSQRRSYWRWRKQDFFPEFSFQSFSTYKSALSATCPRLADRLLSRSSDAYELDAARRESENPMRRCLTWWDLLWLSFGSVVGSGVFVITGQEARVGAGPAVVLSYAISGVSALLSVLCYAEFGVEIPVAGGSFSYLRVELGDFIAFIAAGNILLEAMVGAAGLGRSWSSYLASLVKNDSDYFRIKVDSFAKGFDLLDPVAVAVLLVANGIAMTGTKRTSWLNLITSMVTVCIIVFIVVVGFTHSKTSNLVPFFPYGAKGVVQSAAVVYWSYTGFDMVANMAEETEKPSRDIPIGLVGSMSMITVVYCLMALALTMMVKYTEIDANAAYSVAFAQIGMKWAKYLVGICALKGMTTSLLVGSLGQARYTTQIARSHMIPPWFALVHPKTGTPIYATLLVTILSSIISFFTSLEVLSSVFSFATLFIFMLVAVALLVRRYYVKDVTPEAGLLKFLGFLFLIIASSIGVSALWNSGVKGWIAYTVTGVIWFIGTLGLALLPKYRVPKVWGVPLVPWLPSFSIAMNLFLIGSLGYVAFLRFIICTMVMLLYYLFVGLHATYDVAHQPLEEAKFEGER", "output": "Permease involved in the transport of the cationic neutral or acidic amino acids."}]}
+{"id": "function_test_1069", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIERLKKVSLPALSAFILFCSCHYGRILGVICFDIGQRTSDDSLVVRNRHQFKWFCLSCRLISVTAVCCFCAPYVADIEDPYERLLQCFRLSASLICGICIIVVQVCYEKELLRMIISFLRLFRRVRRLSSLKRIGFGGKREFFLLLFKFICLVYELYSEICQLWHLPDSLSLFATLCEIFLEIGSLMIIHIGFVGYLSVAALYSEVNSFARIELRRQLRSLERPVGGPVGRKQLRIVEYRVDECISVYDEIERVGRTFHRLLELPVLIILLGKIFATTILSYEVIIRPELYARKIGMWGLVVKSFADVILLTLAVHEAVSSSRMMRRLSLENFPITDHKAWHMKWEMFLSRLNFFEFRVRPLGLFEVSNEVILLFLSSMITYFTYVVQYGIQTNRL", "output": "Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates."}]}
+{"id": "function_test_1070", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIGTSSGTSHNRSRKKKEQCGSCPNRFSKDKRQVAAEDSDTTEVESSTDEEERWKEVARAAEIPADYYNIQKLVKYIKAGNQTATIVSLCCLKDYDLSTQINQFAISDIGGLDVLVNILECSDTKCCLGALKVLSDITLNIDIRKTIVDLDGIPLIVDILNSSMKDLKTMAAETLANVCKVRLARKYVRTCGGIPKLVDLIDIKLSILKTPRDQLSPDDLESLDMTRAGARALFTLADSKHNMEQMRKSGIVPLMAQLLKSCHIDVVIPIMGTVRKCSSEPKFQLAITTEGMIPDIVSHLSSENTELKMEGSTAIYKCAFDGTTRDLVREAGGLEPLVTIIKDKNVRENKPLLRGATGAIWMCAVTDANVKVLDQLRTVNHLVALLNDECDEVLTNVTGAISECVRFQSNREQLRQAGGLPAMVSLLNSSHAPLLENLAKGLKECAEDPDSMRILEDLDAVRLIWSLLKNPTTRVQAHAAYAICPCVRNANDSAELVRSLVGAMELVVGLLKSKDIMVLSAVCAAIATIAQDQTNLAILTDLKVIYKLADLVQTTDDLLRMNLAAAVAACACFGNNTEELGRLRTVTPIVTYMTSDNPLVHRSTAMALEKLSMDPQNCITMHQSGVVPFLLECIGSTNKELQLAAAGCLRNIRELALRAEEYLLKIDDD", "output": "Important for spermatogenesis where it may have a role in sperm individualization."}]}
+{"id": "function_test_1071", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSVDPLSSKALKIKRELSENTPHLSDEALMGLSVRELNRHLRGLSAEEVTRLKQRRRTLKNRGYAASCRVKRVCQKEELQKQKSELEREVDKLARENAAMRLELDALRGKCEALQGFARSVAAARGPAALVAPASVITIVKSAPSPGPGPAPGPGPASGPGPAPGPAPAACS", "output": "Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2L1/NRF1, and recruiting them to specific DNA-binding sites. Interacts with the upstream promoter region of the oxytocin receptor gene. May be a transcriptional enhancer in the up-regulation of the oxytocin receptor gene at parturition."}]}
+{"id": "function_test_1072", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MASESKSYARRDRLLEIEATVRKWWEDEDVFRAESCENLPKPGEKFFSTFPFPYMNGYLHIGHAFSLSKVDFASAYHRLRGANVLLPFGFHCTGMPIKASADKLRREIEQFGNPPVFTAEDTTKVPEVQEESSDTIALPIPGQFKGKKSKVAAKAGGQVYQWEIMRSFGLTDSEIANFREPSEWLYYFPPLAVEDLRAYGLGCDWRRSFVTTDVNPFFDAFVRWQMRKLKSMGKIVKDRRYTIFSPLDGQPCADHDRATGEGVQPQEYTLIKMEVVKPFPLKLGPLEGKRVFLAAATLRPETMYGQTNAWVLPDGKYGAYEISETEVFILTERAALNLAYQNFSKNPQEPSCLVELTGYDLIGLPLRSPLSVNEIIYALPMLTILTNKGTGIVTSVPSDAPDDYMALQDLIKKPALQDKYGVKTEWLPTEIIPIINIPEFGDKAAEKVCLDLKIKSQNDKEKLAEAKRLTYLKGFTEGTMLIGEFFGRKVQEIKPIIKTKLIETGEAIIYSEPEKPVMSRSGDECVVALTDQWYITYGESEWRKIAEECLSKMNLYSDETRHGFEHTLSWLNQWACSRSFGLGTRIPWDEQFLVESLSDSSLYMAYYTVAHIFHDGDMYKGSKSLIRPQQMNDEVWEYLFCDGPYPKSSDIPSAVLSEMKQEFDYWYPLDLRVSGKDLIQNHLTFFIYNHTALMANRNWPRGIRCNGHIMLNSEKMSKSTGNFRTLRQSIEEFSATGTRFCLADAGDGVDDANFAFETANAAILRLTKELTWMEEVLDVESSLRTGPPSTYADKVFENDMNIALRLTERAYKDCLFREALKNGFYDLQAARDEYRLSCGTGGMHHDLLLKFMDVQTRLIVPICPHFADYVWRKVLNKEGCVLTAGWPPSNEPDLVLKSANKYLQDSIVLMRKLLQKQLSGSKKGAKKGAQVTAVPEGKLKGLVYVNEQFDGWRAHCLRILQSRFDQQTCSFPPDTEMLAELSATLLQEGKNLKAIQKVCMPFLKFKKDEAISIGTQALNLRLPFGEIEVLQSNKDLIRRQLGLEEVEIYSASDPDDVSIAGPHASLLTQNPPSPGSPTAIFVTSTSVCPPS", "output": "Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA."}]}
+{"id": "function_test_1073", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTEQTIAHKQKQLTKQVAAFAQPETKNSLIQLLNTFIPFFGLWFLAYLSLDVSYLLTLALTVIAAGFLTRIFIIFHDCCHQSFFKQKRYNHILGFLTGVLTLFPYLQWQHSHSIHHATSSNLDKRGTGDIWMLTVNEYKAASRRTKLAYRLYRNPFIMFILGPIYVFLITNRFNKKGARRKERVNTYLTNLAIVALAAACCLIFGWQSFLLVQGPIFLISGSIGVWLFYVQHTFEDSYFEADENWSYVQAAVEGSSFYKLPKLLQWLTGNIGYHHVHHLSPKVPNYKLEVAHEHHEPLKNVPTITLKTSLQSLAFRLWDEDNKQFVSFRAIKHIPVSLPPDSPEKQKLRKNA", "output": "Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsaturated fatty acids."}]}
+{"id": "function_test_1074", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAAASSVLRCCLLVAALMTLSAMGAEAITRQYLFDVQTTSVTRLCSTKSIVTVNGQYPGPTLFAREGDHVEVTVVNHSPYNMSIHWHGIRQLLSGWADGPSYITQCPIQPGGSYVYRFTITGQRGTLWWHAHISWLRATVHGPMVILPPAGVGYPFPAPHEEVPIMFGEWWNNDTEAVISQALQTGGGPNISDAYTLNGLPGPLYNCSAQDTFKLKVKPGKTYMLRLINAALNDELFFSIANHTLTVVDVDALYVKPFTVDTLIIAPGQTSNVLLTAKPTYPGASYYMLARPYTTTQGTFDNTTVAGVLEYDDPCPTTAAGKIVPIFSPTLPQINDTNAVSNFTAKLRSLASAGYPAAVPQQVDHRFFFTVGLGTHPCAVNGTCQGPNGSRFAASINNVSFVLPATALLQSHFAGKSKGVYASNFPYYPLNPFNYTGTPPNNTNVMNGTKVLVLPYGANVELVMQDTSILGAESHPLHLHGFNFFVVGQGFGNFDPINDPAKFNLYDPVERNTVGVPAGGWVAIRFHADNPGVWFMHCHLEVHMSWGLKMAWLVLDGSRPDQKLPPPPLDLPKC", "output": "Lignin degradation and detoxification of lignin-derived products."}]}
+{"id": "function_test_1075", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MFKTISNFMRVSDIRNKIIFTLLMLIVFRIGAFIPVPYVNAEALQAQSQMGVFDLLNTFGGGALYQFSIFAMGITPYITASIIIQLLQMDVVPKFTEWSKQGEVGRRKLAQFTRYFTIVLGFIQALGMSYGFNNLANGMLIEKSGVSTYLIIALVLTGGTAFLMWLGEQITSHGVGNGISIIIFAGIVSSIPKTIGQIYETQFVGSNDQLFIHIVKVALLVIAILAVIVGVIFIQQAVRKIAIQYAKGTGRSPAGGGQSTHLPLKVNPAGVIPVIFAVAFLITPRTIASFFGTNDVTKWIQNNFDNTHPVGMAIYVALIIAFTYFYAFVQVNPEQMADNLKKQGGYIPGVRPGKMTQDRITSILYRLTFVGSIFLAVISILPIFFIQFAGLPQSAQIGGTSLLIVVGVALETMKQLESQLVKRNYRGFMKN", "output": "The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently."}]}
+{"id": "function_test_1076", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPLLKLWAGSLVMLAAVSLPLQAASPVKVGSKIDTEGALLGNIILQVLESHGVPTVNKVQLGTTPVVRGAITSGELDIYPEYTGNGAFFFKDENDAAWKNAQQGYEKVKKLDSEHNKLIWLTPAPANNTWTIAVRQDVAEKNKLTSLADLSRYLQEGGTFKLAASAEFIERADALPAFEKAYGFKLGQDQLLSLAGGDTAVTIKAAAQQTSGVNAAMAYGTDGPVAALGLQTLSDPQGVQPIYAPAPVVRESVLREYPQMAQWLQPVFASLDAKTLQQLNASIAVEGLDAKKVAADYLKQKGWTK", "output": "Part of an ABC transporter complex involved in low-affinity glycine betaine uptake. Binds glycine betaine with low affinity."}]}
+{"id": "function_test_1077", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVRDLVTLPSSLPLITAGFATDQVHLLIGTGSTDSVSVCKNRIHSILNAGGNPIVVNPSSPSHTKQLQLEFGKFAKFEIVEREFRLSDLTTLGRVLVCKVVDRVFVDLPITQSRLCEEIFWQCQKLRIPINTFHKPEFSTFNMIPTWVDPKGSGLQISVTTNGNGYILANRIKRDIISHLPPNISEVVINMGYLKDRIINEDHKALLEEKYYQTDMSLPGFGYGLDEDGWESHKFNKLIREFEMTSREQRLKRTRWLSQIMEYYPMNKLSDIKLEDFETSSSPNKKTKQETVTEGVVPPTDENIENGTKQLQLSEVKKEEGPKKLGKISLVGSGPGSVSMLTIGALQEIKSADIILADKLVPQAILDLIPPKTETFIAKKFPGNAERAQQELLAKGLESLDNGLKVVRLKQGDPYIFGRGGEEFNFFKDHGYIPVVLPGISSSLACTVLAQIPATQRDIADQVLICTGTGRKGALPIIPEFVESRTTVFLMALHRANVLITGLLKHGWDGDVPAAIVERGSCPDQRVTRTLLKWVPEVVEEIGSRPPGVLVVGKAVNALVEKDLINFDESRKFVIDEGFREFEVDVDSLFKLY", "output": "Siroheme synthase involved in methionine biosynthesis."}]}
+{"id": "function_test_1078", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQQRLIYSGKQMNDEKTAADYKILGGSVLHLVLALRGGGGLRQ", "output": "Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis via its conjugation to a limited number of cellular proteins, such as cullins or p53/TP53. Attachment of NEDD8 to cullins is critical for the recruitment of E2 to the cullin-RING-based E3 ubiquitin-protein ligase complex, thus facilitating polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. Attachment of NEDD8 to p53/TP53 inhibits p53/TP53 transcriptional activity. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M."}]}
+{"id": "function_test_1079", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSLIGKEVLPFEAKAFKNGEFIDVTNEDLKGQWSVFCFYPADFSFVCPTELEDLQEQYAALKELGVEVYSVSTDTHFVHKGWHDSSEKISKITYAMIGDPSQTISRNFDVLDEETGLADRGTFIIDPDGVIQTVEINAGGIGRDASNLVNKVKAAQYVRQNPGEVCPAKWEEGGETLTPSLDLVGKI", "output": "Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides."}]}
+{"id": "function_test_1080", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKSQQITHANNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPMKNGGVGIKVMYMDEEHLFSVEQITAMLLTKLKETAENNLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDAKLVEYFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRAQFEELCADLLQKIEVPLYLLMEQTQLKVEDVSAVEIVGGTTRIPAVKEKIAKFFGKDVSTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLVWSHDSEDAEGVHEVFSRNHAAPFSKVLTFLRSGPFELEAFYSDPQGVPYPEAKIGRFIVQNVSAQKDGEKSRVKVKVRVNTHGIFTISTASMVEKIPAEENEVSSLEADMDCQNQRPPENPDAEKNIQQDNNEAGTQPQVQTDGHQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQKFLRLLTETENWLYEEGEDQAKQAYVDKLEELMKIGTPIKVRFQEAEERPKIFEELGQRLQHYAKIAADFRNNDEKYNHIDESEMKKVEKSVNEMMEWMNNVMSAQAKKSLDQDPVVCAQEIRAKIKELNNNCEPVVTQPKPKIESPKLERTPNGPSTDKKEEDLDGKNNFSAEPPHQNGECYPNEKSSINMDLD", "output": "Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering substrate release. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities."}]}
+{"id": "function_test_1081", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIFVLLSAVLLGVFTYSVWIWSYFIRKGIKGPRGFPGIGMLIQTIDHENPPFLKYRDWTKQYGPVYGFTEGPQQTMIISEPEMVNEIFKKQFDNFYGRKLRPIIGDPEKDKRVNIFSTQGKRWKRLRTLSSPSFSNNSLRKVRNSVQECGTEILWNIEQKVRKNEDIDMLIVYQEYTLGVISRIALGQSESNMFKNPLLPKVQAIFNGSWHVFLITGIFPPLAGVFRKMSKMLPASFIPAFKIFDLIEVAVQARIDQRAKDEIKGVEPGEPQDFIDLFLDARVPDVKILSGEANEDFAKSSVVKINKELTFDEIIAQCFVFLAAGFDTTALSLSYATYLLATHPEIQTKLQEEVDRECPDPEIFFDHLSKLKYLECVMKETLRLYPLGTTANTRKCMRETTINGVNFDEGMNIQVDTWTLHHNPRIWGEDVEDFKPERWENGACEHLEHNGSYIPFGSGPRQCIGMRLAQMEQKILLAQILKEYSFRTTKNTQIPVKLVGKLTLSPESVIVKLEPRDS", "output": "Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics."}]}
+{"id": "function_test_1082", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEGQSVEELLAKAERDEAEKLQRITVLKELELEFDLGNLLASDRNPPTGLRHAGPTQEAELRALARDNTQLLINQLWQLPTERVEEALVARLPEPSTRLPREKPVPRPRPLTRWQQFARLKGIRPKKKTNLVWDEVSGRWRRRWGYQRARDDTKEWLIEVPGNADPMEDQFAKRIQAKKERVAKNELNRLRNLARAHKMQLPSAAGMHPTGHQSKEELGRAMQVAKVSTASVGRFQERLPKEKAPRGSGKKRKFQPLFGDFAAERKSQLEMLRVMNSKKPQMDITRATNKQMREEDQEEAAKRRKMSQKGKRKGGRQGPGSKRKGGTPSQGGKRKGGLGGKMNSGPPGLSGKRKGGQHQGGKRRK", "output": "Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus."}]}
+{"id": "function_test_1083", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAAVTVEITRSEVLRPSPASAGGGEMVPLTVFDRAATDGYIPTMFAWDAAAAAALSNDAIKDGLAAVLSRFPHLAGRFAVDERGRKCFRLNNAGARVLEASAAGDLADALAHDVAAHVNQLYPQADKDRVDEPLLQVQLTRYTCGGLVIGAVSHHQVADGQSMSVFFTEWAAAVRTAGAALPTPFLDRSAVAAPRIPPAPAFDHRNVEFRGEGSRSHSYGALPLERMRNLAVHFPPEFVAGLKARVGGARCSTFQCLLAHAWKKITAARDLSPKEYTQVRVAVNCRGRAGPAVPTDYFGNMVLWAFPRMQVRDLLSASYAAVVGVIRDAVARVDERYIQSFVDFGEVAAGDELAPTAAEPGTAFCPDLEVDSWIGFRFHDLDFGGGPPCAFLPPDVPIDGLLIFVPSCAAKGGVEMFMALDDQHVEALRQICYSMD", "output": "Hydroxycinnamoyl transferase that catalyzes the transfer of an acyl from p-coumaryol-CoA to tryptamine, to produce coumaroyl tryptamine. Serotonin, tyramine, and to a lesser extent agmatine, serve as acyl acceptors in vitro. Can use caffeoyl-CoA, and to a lesser extent benzoyl-CoA, as acyl donors."}]}
+{"id": "function_test_1084", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MATDELASKLSRRLQMEDEGGEATEQPGLNGAAAAAAEAPDETAQALGSADDELSAKLLRRADLNQGIGEPQSPSRRVFNPYTEFKEFSRKQIKDMEKMFKQYDAGKDGFIDLMELKLMMEKLGAPQTHLGLKSMIQEVDEDFDSKLSFREFLLIFRKAAAGELQEDSGLHVLARLSEIDVSTEGVKGAKNFFEAKVQAINVSSRFEEEIKAEQEERKKQAEEVKQRKAAFKELQSTFK", "output": "May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance."}]}
+{"id": "function_test_1085", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDDSKVVGGKVKKPGKRGRKPAKIDLKAKLERSRQSARECRARKKLRYQYLEELVSSRERAICALREELEMYKQWCMAMDQGKIPSEIRALLTGEEQNKSQQNSSRHPKAGKTDANTNSLVGN", "output": "Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle (By similarity)."}]}
+{"id": "function_test_1086", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MMPRAQLTTFLIVTSFLSTVPYLRAPVHGGVLTSYDVSSLDIMSKIHTDHDATTKASSDFGHIVHATPNGVFRPTFPADIAALIRLSLSQPTPFTVAPRGKGHSSRGQAFAPGGIVVDMSALGDHGHHTSHRIDVSVDRMYVDAGGEQLWIDVLHTALKHGLTPRVWTDYLRITVGGTLSNAGIGGQAFRHGPQISNVHELDVVTGMGEMITCSPEVNSALFFAVLGGLGQFGVITRARIRLEPAPKRVKWVRIAYSDVHPFTTDQELLISKWASGSGFDYVEGQVQLNRTLTQGRRSSSFFSATDLARLTGLAIDTGSVAIYYIEGAMYYDDNTAASVDQKLDALLEELSFVRGFVFVRDASYVEFLDRVGREEQNLRSAGAWDVPHPWLNLFVPRSRILHFDAAVFKGILRNANPVGLILMYPMNKDMWDDRMTAMTPDEDVFYAVGLLRSAVAGGSGGDVEQLERENAAVLELCDLAGGGIGCRQYLPHHASRDGWRRHFGAKWGRVADLKARYDPRAILSPGQGIFPPPPPPSPPPPAAGEPITAS", "output": "Catalyzes the oxidation of cytokinins, a family of N(6)-substituted adenine derivatives that are plant hormones, where the substituent is an isopentenyl group."}]}
+{"id": "function_test_1087", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEPKKIVPLLRPHPPVVGKVTHHSIELYWDLEKREKRQGPQEQWLRFSIEEEDPKMHNYGVIYTGYATKHVVEGLEPRTLYRFRLKVTSPSGEYEYSPVVSVATTREPISSEHFHRAVNVNDEDLLLRILEGGHVMVDVPNKFGFTALMVAAQKGYTRLVKILISNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRKHGASWDARDLGGCTALHWAADGGHCPVIDWMIKDGCEVDVVDTGSGWTPLMRVSAVTGSQKVASLLIEAGADVNVRDKDGKTPLMVAVLNNHEQLVQLLLDKGADATVKNEFGKGVLEMARVFDRQNVLSLLEERKKKMPRKSSVH", "output": "Through the activation of JUN and AP-1-mediated transcription, may regulate apoptosis."}]}
+{"id": "function_test_1088", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDSHNSAPPQIAEVRMDISSSTSVAAGNKVCRGAACDFSDSSNSSKDARERMASMRKLIIAVILCIIFMAVEVVGGIKANSLAILTDAAHLLSDVAAFAISLFSLWAAGWEATPQQSYGFFRIEILGALVSIQLIWLLAGILVYEAIVRLINESGEVQGSLMFAVSAFGLFVNIIMAVLLGHDHGHGHGHGHGHGHSHDHDHGGSDHDHHHHEDQEHGHVHHHEDGHGNSITVNLHHHPGTGHHHHDAEEPLLKSDAGCDSTQSGAKDAKKARRNINVHSAYLHVLGDSIQSIGVMIGGAIIWYKPEWKIIDLICTLIFSVIVLFTTIKMLRNILEVLMESTPREIDATSLENGLRDMDGVVAVHELHIWAITVGKVLLACHVTITQDADADQMLDKVIGYIKSEYNISHVTIQIERE", "output": "Involved in sequestration of excess zinc in the cytoplasm into vacuoles to maintain zinc homeostasis."}]}
+{"id": "function_test_1089", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MENSSAASASSEAGSSRSQEIEELERFIDSYVLEYQVQGLLTDKTEGDGESQRTQSHISQWTADCREQLDGSCSFSRGRAPPQQNGNKDNSLDMLGTDIWAANTFDSFSGATWDLQPEKLDFTQFHRKVRHTPKQPLPHIDREGCGKGKLEDGDGISLNDIEKVLPTWQGYHPMPHEAEIAHTKKLFRRRRNDRRRQQRPPGGNKPQQHGDHQPGSAKHNRDHQKSYQGGSGPHPSGRPTHHGYSQNRRWHHGNMKHPPGDKGEAGSHRNAKETVTVENPKLEDGPGDTGHSGLEPPCSPDTLTPAASERPTPQLPGGPEAEIKHKDTVLPERLRERPKITLLQSSKDRLRRRLKEKDRDEVAVETSSPQPSKMDRLMEILNIMRNNSSDVDAKLTSFMEEAQNSTNSEEMLGEIVRTIYQKAVSDRSFAFTAAKLCDKMALFMVEGTKFRSLLLNMLQKDFTVREELQQQDVERWLGFITFLCEVFGTMRSSTGEPFRVLVCPIYTCLRELLQSQDVKEDAVLCCSMELQSTGRLLEEQLPEMMTELLASARDKMLCPSESMLTRSLLLEVIELHANSWNPLTPPITQYYNRTIQKLTA", "output": "Specifically required for the pioneer round of mRNA translation mediated by the cap-binding complex (CBC), that takes place during or right after mRNA export via the nuclear pore complex (NPC). Acts via its interaction with the NCBP1/CBP80 component of the CBC complex and recruits the 40S small subunit of the ribosome via eIF3. In contrast, it is not involved in steady state translation, that takes place when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. Also required for nonsense-mediated mRNA decay (NMD), the pioneer round of mRNA translation mediated by the cap-binding complex playing a central role in nonsense-mediated mRNA decay (NMD) (By similarity)."}]}
+{"id": "function_test_1090", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSEKIHITQNSGNVDHTVEALGHAISGGVAGMAAIALTYPFSTVSTRLQVQQKKQQQGQQSEITTVPYKNSIDAFKRIIKEENWRTLYSGLKSALIGIGASSFVYYYWYTLLKSISLKLKNKQELGTIENLAIAALAGCANVLTTLPIWVVNTRLQINSDKGIVGQFKYIIKNEGFGGLYKGLIPALILVSNPSVQFVSYEKLRALWRRQSGRTKLGGLEVFILGAIAKLIAGIVTYPYLLVKSRLQSQSGNASNPESQQQQYKGTLDAIGKIFKSDGFLGFFKGMPSKMVQTVIGAAFMFLVKDKVVIHAVAILFYLKRLLNKNNKRV", "output": "May have transport activity."}]}
+{"id": "function_test_1091", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MADAVLFEFLHTEMVAELWAPDPDPGSGGKRRSLSVLEGLGFRVGQALGERLPLETPAFREELDALKFLCRDLWAAMFQKHMDGLRTNHQGTYVLQDNSFPLLVTMGSGPQYLEEAPKFLAFTCGLLCGALHTLGFQSLVTASVASLPACKFQVVIQKS", "output": "May play a role in vesicular transport during the biogenesis of melanosomes."}]}
+{"id": "function_test_1092", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDFPGHFEQIFQQLNYQRLHGQLCDCVIVVGNRHFKAHRSVLAACSTHFRALFSVAEGDQTMNMIQLDSEVVTAEAFAALIDMMYTSTLMLGESNVMDVLLAASHLHLNSVVKACKHYLTTRTLPMSPSSERAQEQSARMQRSFMLQQLGLSIVSSALSSSQSAEEPTAPMSSSMRSSLDQRTPFPMRRLHKRKQSVEERARQRLRSSMEESAISDVTPESGPAGVHSREEFFSPDSLKIVDNPKPDGMADNQEDGAMMFDRPFGAQEDAQVPSQSDGSAGNMASRATQVETSFEQEAVAEKGSFQCENPEVGLGEKEHMRVVVKSEPLSSPEPQDEVSDVTSQAEGSESVEVEGVVVSAEKIDLSPESSDRSFSDPQSSTDRVGDIHILEVTNNLEHKTSFSISNFLNKSRGSNFSASQSTDDNLPNTTSDCRLEGEAPYLLSPEAGPAGGPSSAPGSHVENPFSEPADSHFVRPMQEVMGLPCVQTSGYQGEQFGMDFSRSGLGLHSSFSRAMMGSPRGGASNFPYYRRIAPKMPVVTSVRSSQISENSASSQLMMNGATSFENGHTSQPGPPQLTRASADVLSKCKKALSEHNVLVVEGARKYACKICCKTFLTLTDCKKHIRVHTGEKPYACLKCGKRFSQSSHLYKHSKTTCLRWQSSNLPSTLL", "output": "May be involved in transcriptional regulation."}]}
+{"id": "function_test_1093", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAHRRIALAVLVTLLLSAFRPCLAQQSNDDTSKHHRSATAGGFTPTTVVVLVALITAFVLLTVFSVLINRCAQARAPPRRAFRSTASHQPVGGAAAASRASRGLDKEVVEAFPTAVYGDVKARMAAKSGPLECAVCLAEFADSDELRVLPACCHVFHPDCIDPWLAAAVTCPLCRANLTAPPVSLAAAESSDLTAPEEAVQEEESEELDEASLMATFTPESVIDFGATHDHEFDRAGYPHYRRTQSAMDAAPDRHTLRLPEHVMKELAADRRHRRAASLAGYPDSVERTPRWLTSLWRSVSWQRQSRADWDAGEEHGGSKRVHPVAGAQDETPSGSGSDGSKENSDSDALNRV", "output": "Possesses E3 ubiquitin-protein ligase in vitro."}]}
+{"id": "function_test_1094", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPKLQGFEFWSRALGGARHVVAPMVDQSELAWRLLSRRHGAQLCYTPMLHAQVFVRDANYRKENLYCDVCPEDRPLIVQFCANDPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGRYGAFLQEEWDLLQRMILLAHERLSVPVTCKIRVFPEIDKTVRYAQMLEKAGCQLLTVHGRTKEQKGPMAGTASWEHIKAVRKAVGIPVFANGNIRCLQDVERCIQDTGVQGVMSAEGNLHNPALFEGRSPAVWELADEYLDIVRQHPCPLSYVRAHLFKLWHHTLQVHQQLREELAKVKTLEGVAAVSQALKLRCQEDMARQQEGVRPADNLPAFHWICQPYIRPGPKEGSKENSSGRSKRALEEEEGSMEGLSKNKLKKQLRNPHKTFDPSLKPKYAKCDQCGNPKGNRCVFNLCRGCCKKRAFRETADCPGHDCFLRPN", "output": "Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs."}]}
+{"id": "function_test_1095", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNSLVRRKQVDSVHLIKNDGPHQLAKKLSAVDLVAIGVGTTIGAGVYILVGTVAREHTGPALAVSFFIAGVAAALSACCYAELASRCPSAGSAYHYAYICLGEGIAWLVGWALVLDYTIGGSAIARGITPNLASFFGGLDNLPVFLARQTIPGVGIVVDPCAALLIMIVTILLCFGIKESSTVQAIVTSVNVCTLVFIIVVGGYLACKTGWVGYDLPSGYFPFGLNGILAGSAVVFFSYIGFDTVTSTAEEVKNPQRDLPLGIGIALLICCILYMLLSVVIVGLVPYYSLNPDTPISSAFGDSGMQWAAYILTTGAITALCASLLGSLLAQPRIFMAMARDGLLPAFFSEISPRTQVPVKSTIAIGVLAAALAFFMDVAQLSEMVSVGTLMAFTAVAVCVLVLRYVPPDGVPLSSSSQTLSDTDESRAETENFLVDAIESSDSPLLGNETARDEKYFGKRRKIAAWSIALVCIGVLGLASAASAERLPSFPRFTICGVSAVILLGSLITLGYIDEDEERHNFGHKGGFLCPFVPYLPVLCILINTYLIINIGAGTWIRVLIWLLIGSMIYIFYGRSHSLLNNAVYVPTMTCTRKTTDHLA", "output": "Permease involved in the transport of the cationic amino acids."}]}
+{"id": "function_test_1096", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPHLGPLRRRAWAALLGQLLRPPSTVCTRGCHSQVAKAVLTSEQLKSHQEKPNFVIKVPKGTRDLSPQQMVVREKILDKIISCFKRHGAKGLDTPAFELKEMLTEKYEDNFGLMYDLKDQGGELLSLRYDLTVPFARYLAMNKLKKMKRYQVGKVWRRESPAIAQGRYREFCQCDFDIAGEFDPMIPDAECLRIMCEILSGLQLGDFLIKVNDRRVVDGIFAVCGVPESKLRTICSSMDKLDKMSWEGVRHEMVAKKGLAPEVADRIGDFVQYHGGISLVEDLFKDPRLSQSQLALQGLGDLKLLFEYLRLFGIADKISLDLSLARGLDYYTGVIYEAVLLESPAQAGKETLSVGSVAAGGRYDNLVAQFDPKGHHVPCVGLSIGVERIFYLVEQKMKMSGEKVRTTETQVFVATPQKNFLQERLKIIAELWDAGIKAEMLYKNNPKLLTQLHYCEKADIPLMVIIGEQERNEGVIKLRSVASREEVTINRESLVAEIQKRLSES", "output": "Mitochondrial aminoacyl-tRNA synthetase that catalyzes the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP)."}]}
+{"id": "function_test_1097", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLSAAEGILLSIATVEAGLGVLGNTFIALVNCMDWAKNKKLSKIGFLLFGLATSRIFIVWILILDAYAKLFFPGKYLSKSLTEIISCIWMTVNHMTVWFATSLSIFYFLKIANFSHYIFLWLKRRTDKVFAFLLWCLLISWAISFSFTVKVMKSNPKNHGNRTSGTHWEKREFTSNYVLINIGVISLLIMTLTACFLLIISLWKHSRQMQSNVSGFRDLNTEAHVKAIKFLISFIILFILYFIGVAVEIICMFIPENKLLFIFGLTTASVYPCCHSVILILTNSQLKQAFVKVLEGLKFSENGKDLRAT", "output": "Gustducin-coupled cycloheximide receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5."}]}
+{"id": "function_test_1098", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQMEANDCQEEHKFTLDNYHVVEQVRRGKSSSDFVVLHDIEDKKYAMKKICLAKHTDKLKQTALQEMKLLSSLKNPYIVHYEDSWIDNDNNACIFTAYYEGGNMANAIKKARGKLFPEERIFKWLAQLLLAVNYLHSNRVVHMDLTCSNIFLPKDDHVQLGNYGLAKLINPEKPVSMVSGISNSMCPEVLEDQPYGYKSDIWSLGCCMYEITAHQPAFKAPDMAGLINKINRSLMSPLPIVYSSTLKQMIKLMLRKKPEYRPTACELLRNPSLQPYLLQCQNLSPIYLPVFPIKPVNSPKDKARRNSLPGKFGKERVSREKSEVSRSLENLYPFWTNTETGSSSSSQPASSTNGAEDKLETKRIDPSCDTLKISEFTSQKSDESLIDPDIAVYSTETPAEENALPKETENIFSEESQLRDVDVGVVSAQEVACSPPRAIEEAETQEALPKPKEQITVPISSVAHSSTEVAAAKDHLSGSLEGDKAKMVKLTASEMSSVLSKLTKLGPPQSKERADALECLLEKCAGLVKQEKYEELAGLLTPFGEDGVSARDTAIWFAKTLLSSDKLNQGT", "output": "May be involved in plant development processes."}]}
+{"id": "function_test_1099", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGPISSSWSFNKFFSIVFVVFAISGEFVAGYYRPGPWRYAHATFYGDETGGETMGGACGYGNLFNSGYGLSTAALSTTLFNDGYGCGQCFQITCSKSPHCYSGKSTVVTATNLCPPNWYQDSNAGGWCNPPRTHFDMAKPAFMKLAYWRAGIIPVAYRRVPCQRSGGMRFQFQGNSYWLLIFVMNVGGAGDIKSMAVKGSRTNWISMSHNWGASYQAFSSLYGQSLSFRVTSYTTGETIYAWNVAPANWSGGKTYKSTANFR", "output": "Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found (By similarity)."}]}
+{"id": "function_test_1100", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSELNMELKKLRELELKTQGLAARIQTAKSGEQLDVDLVQLQIENKKLKNRLFILKKSIAEESTAAGGDVSKPKESSSITEHLESVFRQAIASAFPEFRDTPVIIAPVNSTSAKFGDYQCNNAMGLSKKLKEKGINKAPRDIATELKGHCPASPIIEKLEIAGAGFVNVFLSKDYASLALSNLLRNGVKPPEVIKKRVLVDFSSPNIAKQMHVGHLRSTIIGESLCRLLEFLQHDVIRINHLGDWGTQFGMLIAHLEDRFPNYLNESPPISDLQLFYKESKKRFDEDEEFKKRAYSRVVSLQKGVPNSIKAWELICNVSRKEFQTIYERLDISVKERGESFYQSRMLSVVEYLRGKGLLEVDEGREIMWPDDTKTGIPLTIVKSDGGFTYDTSDMAAIRHRLEEELCDWIIYVVDSGQSTHFNTIFKAAERSAILNPLSHRVDHVQFGVVLGEDGKKFKTRSGDTVKLSDLLDEGMKRSLQQLESRGRDKVLTPQELKDAQESLAYGCIKYSDLCHNRISDYIFSFDKMLEDRGNTAVYLLYTYTRICSIARNSGEDFTNLPEILKKTNIVLDHEKEWKLAKTLLKLHDILIKCSKELFLHFLCEFCFEVCTVFTEFYDSCYCIEKNKQGDIIGVNHSRILLCEATAAVLRQCFYILGLKPVSKM", "output": "Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis."}]}
+{"id": "function_test_1101", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRKIIHIDMDCFYAAVEMRDNPALREVPLAIGGSADRRGVISTCNYVARRFGVRSAMPSALARKLCPPLVLIPGRMAVYKEVSRLLRAIFLRYTEQVEPLSLDEAYLDVTMSPCCGGSATLMAREIRAAINTELGLTASAGVAPNKFLAKLASEQRKPDGLFVIRPQEVDEFVRQLPLGKLPGIGRKTADRLESLGLYSCEDARQLGNEELIARFGKLGEMLAGRIWGHDEQPVQAQRVRKTIGVETTLASDVLDEAACWQVLRQLIPELEQRFSVSHGKEQLMGQGIKLKFADFQQTTVYRRGGYQPERFHDLLHEGLLRAQGKPIRLLGLVVGLPAAGEVNQLALDLA", "output": "Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII."}]}
+{"id": "function_test_1102", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MVFDAVGNPQTILLLGGTSEIGLAICERYLRNASARIVLAVMPGDPGRDAAVEQMRKAGASAVDVVDFDALDTESHPAVIDQAFAGGDVDVAIVAFGLLGDAEELWQNQRKAVQIAGVNYTAAVSVGVLLGEKMRAQGSGQIIAMSSAAGERVRRSNFVYGSTKAGLDGFYLGLGEALREFGVRVLVIRPGQVRTRMSAHVKEAPLTVDKEYVAELAVTASAKGKELVWAPGAFRYVMMVLRHIPRPIFRKLPI", "output": "Component of the DprE1-DprE2 complex that catalyzes the 2-step epimerization of decaprenyl-phospho-ribose (DPR) to decaprenyl-phospho-arabinose (DPA), a key precursor that serves as the arabinose donor required for the synthesis of cell-wall arabinans. DprE1 catalyzes the first step of epimerization, namely FAD-dependent oxidation of the C2' hydroxyl of DPR to yield the keto intermediate decaprenyl-phospho-2'-keto-D-arabinose (DPX) . The intermediate DPX is then transferred to DprE2 subunit of the epimerase complex, most probably through a 'substrate channel' at the interface of DprE1-DprE2 complex (By similarity). DprE2 then catalyzes the second step of epimerization, the NAD(+)-dependent reduction of DPX that leads to the formation of DPA ."}]}
+{"id": "function_test_1103", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLKIADVEFESRLFTGTGKFSNSQVMLEAIRASKSQLVTVAMKRIDFKIGLDDLLTPLRQVGVQLLPNTSGARNAKEAVFAAELAREMLGTRWIKLEIHPDPKYLMPDAIETLEAARILCEKGFIVLPYVHADPVLCRRLEEVGCAAVMPLASPIGSNQGLVTESFLKIIIEQARVPVVIDAGIGAPSQAARAMELGADAVLVNTAIASSASPIVMAECFKEAVQCGRRAFEAGLGRVQTGAVQTSPLTGFLNQ", "output": "Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S."}]}
+{"id": "function_test_1104", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNGLSFIDDEQIRFPSPELALSEPNGLLAIGGSLHPKRLLAAYYDGIFPWFNAEDPILWWSPDPRAVFLPGELKISRSLKKSLKKHPWRVTINHAFADVMAGCAQPRKKQRDTWITQEIQLAYLEMHSQGHAHSVEVWMKDRLVGGLYGLAIGKVFCGESMFHRETDASKLAMMALHQHLLQHDFKLLDAQIMNPHLESLGAREVSRTAFLSLLKRYRDEPVAKSCWLPREMPIGK", "output": "Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine."}]}
+{"id": "function_test_1105", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPQYRSKTSTHGRNMAGARALWRATGVKDDDFGKPIIAIANSFTQFVPGHVHLKDMGQLVAGAVEAAGGIAKEFNTIAIDDGIAMGHSGMLYSLPSRDLIADSIEYMVNAHCADAIVCISNCDKITPGMLMAALRLNIPVIFVSGGPMEAGKTKLSDQIIKLDLVDAMVMGPDKNVSDEDLAKVERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSMLATHADREQLFLEAGERIVDITKRHYEQDDYSVLPRAIACREAFENAMALDIAMGGSTNTILHLLACAQEAELDYTVADMDEMSRRIPQLCKVAPSTPLYHMEDVHRAGGVMAILGELDRAGLLNSDIPTILSPTMKEQLAKYDIMQTDDPKIIDFYRAGPAGIRTVKPFSQSCRWDTVDNDRAAGCVRSLEHAFSTEGGLAVLFGNMAVDGAVVKTAGVDNDNLTFTGPAKIYESQDTAVAAILGGKVVEGDVVVIRYEGPQGGPGMQEMLYPTSYLKSMGLGKKCALVTDGRFSGGTSGLSIGHASPEAAAGGVIGLIEDGDIIDINIPTRTMDLKVSDEILAERRIAMDIHGWKPVSRERHVSTALKVYALMATSADKGAIRDISKLK", "output": "Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively."}]}
+{"id": "function_test_1106", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTDNSQVKVIVGMSGGVDSSVSAYLLQQQGYLVEGLFMKNWEEDDTDQYCAAAQDLEDAQSVCDKLGIPLHTINFAAEYWDNVFEHFLAEYKAGRTPNPDIMCNKEIKFKAFLEFAAEDLGADYIATGHYVRRREVDGHVQLLRGLDNNKDQSYFLYAIGEKQIAKSLFPVGELEKPEVRRIAEQQDLITHNKKDSTGICFIGERKFTDFLQEYLPAQPGDIVTPTGEVIGQHQGLMYHTLGQRKGLGIGGLQNSNENPWYVVGKDMDNNRLLVAQGADHPALFSYGLIAKQCDWVDRTPKKSTFRCTVKTRYRQQDIPCTVTPLDDDTLKVIFDTAQAAVTPGQSAVFYNDEVCLGGAIIEEHLQK", "output": "Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34."}]}
+{"id": "function_test_1107", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTTPRMLWDISAPVHAGSPVFPGDTPYSQQWCATIGPQCPVNVSALAMSPHVGTHADAPLHYDPQGATIGDVPLDAFIGPCRVIHAIGRGPLVAWEHIAHALGADRPALPQRVLVRTYERMPLDRWDAALAAYAPDTIERLADLGVVLVGIDTASIDPADSKSLDSHQVIRRRGLRVLENLVLDEVPEGDYELIALPLKLTTADASPVRAVLRTPA", "output": "Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation."}]}
+{"id": "function_test_1108", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSGAVCPGSFDPVTLGHVDIFERAAAQFDEVVVAVLVNPNKKGMFTLDERMEMIAESCAHLPNLRVESGQGLVVDFVRARGYSAIVKGLRSSTDFEYELQMAQMNKHVAGVDTFFIASAPSYSFVSSSLAKEVATLGGDVSALLPDAVNVRLQAKLRG", "output": "Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate."}]}
+{"id": "function_test_1109", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MATILYIKASPRGERSHSVTVADAFVKAYSEANPGDVVRVLDVFEADLPAFGTDAVVARYLSGQGDPLSPAQEAAWAAVKRQVEDFKTADKYVIALPMWNFSIPWRLKQFFDIIIQPGLTFSYDEQGYHGLVTGRPVLVSYARGGAYPAGTPAEGWDFQKRYLEHILGFIGFTDIRSVVVEPTLAGGPDTAQAKRAEAVEQARRMALEF", "output": "Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.; "}]}
+{"id": "function_test_1110", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSAVAPRSRLSLYLDLIRWNRPAGWLVLVWPTLAALWVAADGFPGWHLLAVFVAGTVLMRSAGCTINDIADRDFDRHVKRTTQRPITSGQLGVREAALVGVVLTLVAFVLVLTTRWEAVAWSVPAVLFTILYPFTKRFFAMPQAFLGIAFNFGIVIAFAAVQGRVPATAWVLWLANLFLVLAYDTEYAMVDRDDDLKIGMKTSAITLGRFDVAAIMGFFVLCLGLTAWVLAPYGLGWPLWLGLGVAAAQVAWHFTLIKDRTREGCFTAFSKSHWIGAAIFAGVALGYLLR", "output": "Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate."}]}
+{"id": "function_test_1111", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDEHPPPPFPTVGIIGKPGDPAIAGLVERLLPMLEARGCTALLDEQSMPETGDDRHPQRVSRETLLDACDLIIAIGGDGTLIHIARAVAGRRDVALMGINRGRLGFLVDIAPEHLDEVAQILDGQHVVDERLLLHAEIRSNEDDTLLREDVAINEVVLHRWNTARMIELVTRIDGEPLSDHRSDGLILATPTGSTAYAMAGGGPIVHPNLHAMLLVPVCPHTLSNRPLVVDGSSRIEIDVHPRFIEHVRVSCDSQNDLTLQAGSRLVVRAHPSPVRLVHPPGYSYFNLLRAKLGWGGPLCNIEPFGA", "output": "Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP."}]}
+{"id": "function_test_1112", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAEPTATREQAQQRMAQLRGEISEHDYHYYVLDRPTISDAEYDALFRELQRLEAAYPDLVSSDSPTQRVAGTAQEGFEAVVHDTPMLSLDNAFEADDLVDFDRRIRDRLGVASVVYTGEPKLDGISLSLTYQDGELVRAGTRGDGHTGEDVTANVRTLRSVPLRLRGDGYPGRLEVRGEVVIRKEDFERLNQARLDAGERPFANPRNAAAGSLRQLDPRITARRPLTLFTFGVGDPLALGVESHWQVLECLAGWGFRTTAPLEHLEGVSACQAYRDRLIEERDALPFEIDGAVFKVDDLAVREQLGFTARAPRWALAFKLPAREATTVVEAIVPSVGRTGKITPLARLQPVEVSGVTVARASLHNADELARMDVREGDTVMVRRAGDVIPQITDVVLAKRPEGAQPWRFEERVQACPECGSAVQRIEGEAAHRCVGGLYCPAQREGAILHFASRRALDIDGLGEKIVEQLVAKGLVVDLADLFRLGHAQLAGLERMGDKSADNLLAALDRARSTTLARFLYALGIPHVGEVTARRLAEAAYGLMVAVPRGDRAALRAAAGLDAQTAITSEALLRVMAAPADDLEAIEDVGPVVARAIAGFFAEPHNRQVVDHLCAAGVHWPEPDPPEQAESVSSLAGRAFVVTGTLETMTRDEAKAAIEACGGRVTGSVSRKTDYLVAGADAGSKLNKARELGVEVVNESGLRELLAGAGA", "output": "DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA."}]}
+{"id": "function_test_1113", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPVERTFVMIKPDGVKRGLVGEIIARFERKGLKIKALKMKWLTREEAEKLYEVHRGKPFFEDLVNFVTSGPVVAMILEGDSAIEVVRLMIGPTDGRKAPPGTIRGDYALDIGANVIHASDSKESYEREYKVFFSDDEIVGDY", "output": "Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate."}]}
+{"id": "function_test_1114", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAKLLSFSDESRGALEKGVNNLANALKVTIGPKGRNVVIEKKFGAPDIVNDGVTIAKEIDLEDPFENIGAKLIEQVASKTKEKAGDGTTTATVLAQFMVQEGLRNTAAGASPIELRRGMEKAVAQIVDDLKKKSKSVSGDAIKQVATVSAGGDEEIGSMIADAIDKVSFDGVITVEESKSLATELDITEGMAFDRGYSSPYFVTDEDRLICEFENPSILITDKKISSIADLIPVLETVQKNGTPLIILAEEVEGEALATLVVNKNRGVLQVAAVRAPSFGERRKAALGDIAVLTGGTLISEDKAMSLEKVQISDLGQARRVTITKDSTTIVANDNQNTELSNRIASIKRELDETDSEYDQEKLNERIAKLAGGVAVIKVGAPTETELKNRKLRIEDALNATRAAIEEGIVAGGGTTLLELSEGLGDLAKKLEGDQKTGVEIIKRALTAPTKQIAINAGFNGDVVVSDIKRLGKGFNAQTGEYVDLLEAGILDASKVIRLALQDAVSIASLLITTEVVIADKPEPPSAPGAEGGDPMGGMGGMGGMGGMGGMGGMGGMGMPGMM", "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."}]}
+{"id": "function_test_1115", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MVAFSALSGVSAVSLLLSLVQNAHGISLKVSTQGGNSSSPILYGFMFEDINHSGDGGIYGQMLQNPGLQGTAPNLTAWAAVGDATIAIDGDSPLTSAIPSTIKLNIADDATGAVGLTNEGYWGIPVDGSEFHSSFWIKGDYSGDITVRLVGNYTGTEYGSTTITHTSTADNFTQASVKFPTTKAPDGNVLYELTVDGSVAAGSSLNFGYLTLFGETYKSRENGLKPQLANVLDDMKGSFLRFPGGNNLEGNSAENRWKWNETIGDLWDRPGREGTWTYYNTDGLGLHEYFYWCEDLGLVPVLGVWDGFALESGGNTPLTGDALTPYIDDVLNELEYILGDTSTTYGAWRAANGQEEPWNLTMVEIGNEDMLGGGCESYAERFTAFYDAIHAAYPDLILIASTSEADCLPESMPEGSWVDYHDYSTPDGLVGQFNYFDNLNRSVPYFIGEYSRWEIDWPNMKGSVAEAVFMIGFERNSDVVKMAAYAPLLQLINSTQWTPDLIGYTQSPGDIFLSTSYYVQEMFSRNRGDTIKEVTSDSDFGPLYWVASSAGDSYYMKLANYGSETQDLTVSIPGTSTGKLTVLADSDPDAYNSDTQTLVTPSESTVQASNGTFTFSLPAWAVAVLAAN", "output": "Alpha-L-arabinofuranosidase involved in the degradation of arabinoxylan, a major component of plant hemicellulose. Acts only on small linear 1,5-alpha-linked L-arabinofuranosyl oligosaccharides (By similarity)."}]}
+{"id": "function_test_1116", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEKTQGDAEDLSHALAFTSPKKIYAADYSDCHDADLVVLTAGAPQKPGETRLDLVEKNLRINKEVVTQIVASGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQALAAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDIDEQGLVDLFISVRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQPAIVGAYGIVRPVNIPLNDAELQKMQASANQLKAIIDEAFAKEEFASAAKN", "output": "Catalyzes the conversion of lactate to pyruvate."}]}
+{"id": "function_test_1117", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAGRELSHLQQLEAESIQIIREVAAEFDNPVMLYSIGKDSSVMLHLARKAFYPGKIPFPLLHVDTGWKFKEMIAFRDAQAKKFGFELLTHINPEGLAQGINPFDHGSAKHTDIMKTQGLKQALNQYGFDAAFGGARRDEEKSRAKERVYSFRDRHHRWDPKNQRPELWRTYNGAVNKGESIRVFPLSNWTELDIWQYIYQENIELVPLYFAAKRQVVERGGQLIMADDERMKLAEGEQFKEEVVRFRTLGCYPLTAAMHSEADSLEKIIEEMLLTRSSERQGRLIDSDQSASMEQKKRQGYF", "output": "With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD."}]}
+{"id": "function_test_1118", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNNYNNGDYKGGREQHFGGNNNYNRGYGGNGGFGGNRYNERVELTTPDWDLESLPKFEKNFYTEHPDVAARSDKDIAAFRNEHQMSCLGSDIPHPITTFDEAGFPEYVLNEVKAQGFPSPTAIQCQGWPMALSGRDMVGIAATGSGKTLSYCLPAIVHINAQPLLSPGDGPVVLVLAPTRELAVQIQQECSKFGSSSRIRNTCVYGGAPKGQQIRDLARGVEIVIATPGRLIDMLEMGKTNLKRVTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVQNLARDYLQDPIQVRIGSLELAASHTITQVVEVISEYEKRDRLVKHLETATTEKESKVLIFASTKKTCDEVTSYLRADGWPALAIHGDKQQSERDWVLREFKTGKSPIMVATDVAARGIDVKGINFVINFDMPGNIEDYVHRIGRTGRGGATGTAVSFFTDGNNKLGGDLCKIMREAKQTIPPELQRFDRKSFGAHIRYGGGRGGRGGYGRGRGGYGGRGGYGQRNYQTGSNQAPLSNRRF", "output": "ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing."}]}
+{"id": "function_test_1119", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSTAALVEGKIVQCIGAVIDVEFPRESMPKIYDALILEGSELTLEVQQQLGDGVVRTICLGASDGLRRGVVVKNTGNPISVPVGKPTLGRIMDVLGRPIDEAGPIESENKRSIHQKAPAFDELSPSTELLETGIKVIDLICPFAKGGKVGLFGGAGVGKTVNMMELINNIAKEHGGYSVFAGVGERTREGNDFYHEMKDSNVLDKVALVYGQMNEPPGNRLRVALTGLTMAEHFRDEGLDVLFFVDNIYRFTLAGTEVSALLGRMPSAVGYQPTLAEEMGKLQERITSTKKGSITSVQAVYVPADDLTDPSPATTFGHLDATVVLSRDIASLGIYPAVDPLDSTSRQIDPNVIGEEHYSITRRVQQTLQRYKELRDIIAILGMDELSPEDKLSVARARKIQRFLSQPFHVAEVFTGSPGKYVPLKETIRGFKMIVDGECDHLPEQAFYMVGTIDEAFEKAKKIQ", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits."}]}
+{"id": "function_test_1120", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MATQRKIIHIDMDCFYAAIEMRENPALIGKPVAVGGSVEGRGVLTTCNYEARKFGLHSAMPTAQALKRCPNLILVPVNMPLYKAVSEQIHQIFRRYTDIVELLSLDEAYLDVTDCRQCSGSATWIAQEIRDAIWNELHLTASAGIAPLKFLAKIASDQNKPNGQFVISPENMTAFIYDLPLKKIPRVGKVTNEKLAQLGLHTCGDIQHSDKAFIYKTFGKFGQRLWEFSHAIDNRKIEANRPRKSLAVENTLPTDIWHLAEAEQIVDELFKKLVFRLQRNWGERSLQEFKKLAIKLKFGDFTQTTLERTTDGLSRERFIELLQQVWQRTNRRSVRLIGLSVHYPTEKVKKQLNLWE", "output": "Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII."}]}
+{"id": "function_test_1121", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSKISEVVQRARAAFNSGKTRPLQFRIQQLEALRRMIKEHEKDLAGALTADLHKNEWNAYYEEVVYVLEEIEYMIKKLPEWAADEPVEKTPQTQQDECYIHSEPLGVVLIIGTWNYPFTVTIQPMVGAIAAGNAVVIKPSELSENMANLLATIIPQYLDRDLYPVISGGIPETTELLKERFDHILYTGNTAVGKVIMMAAAKHLTPVTLELGGKNPCYVDKDCDLDIACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKALKEFYGEDAKKSRDYGRIINSRHFQRVMGLMEGQKVAYGGTGDAATRYIAPTILIDVDTQSQVMQEEIFGPVMPIVCVRSLEEAIQFINQREKPLALYVFSLNDKMIKKMIAETSSGGVTANDVIVHVSVHSLPYGGVGNSGMGSYHGKKSFETFSHCRSCLVRPLLNDESLKTRYPPSLAKMTRH", "output": "ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids (By similarity). Preferentially oxidizes aromatic aldehyde substrates (By similarity). Comprises about 50 percent of corneal epithelial soluble proteins (By similarity). May play a role in preventing corneal damage caused by ultraviolet light (By similarity)."}]}
+{"id": "function_test_1122", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEIRRPSRHGNHPDRTYQRTYKACISCRQRKAKCDLGTGPDGLPLGPPCAKCRREQKPCLFDEKRAWERVKKRGTQSTSNLANSMMRTVVSSGNDALNILFEAANAQSQEDSMIESDSLPETEQHRSGHPVTSEGSSNQIDLTVPPDVLEKAMRPVELSHVSKDVLSTWEACRFVRMGWFTAREAVTFIDLFFKNMSILSPVLTDFYADHKNHRWLIAHDPVLCCTILMISSRYHVLPGVGGQSRNFFIHHRLWQHCQQLVTRLIFGQELSSQPKIRNIGTIEALLLMSDWHPRSLHFPPESDGWDSDLVTIDLESTEYGDDGSNSSAKRWAKDMSEPAKRSDQMSWMLLGSALSLAHELGIYETGDKARDAFVAYERFMTKDQMRLRRQRAQRLLYVYINQLAWRIGCVSLMPQGLSHSILNRQTSRELSQYGEEWLTFMDSWMDLTKLAKSVTDMFFPSVTFARQQLQSGRYIDLLDHFRPLLDKWKERYLQPQLHDKPFYDDIFIEYHFVRVYTHSVGMQAVVERAIADGNADEEEVRPMNIDPIDYEYIQEVIDGCCQILEKVTQLADIGALRFSPVRIFVRITSASIFLMKALSLGARQAKLRESLDVLERTIQALRSNALDDIHLSTRYATLLETHVSRLRRHLVASCKSLKRRRESTTRHSMVPPSYASATSDEHAPLITNPPVPQNMSDMGFTPSLNDIAADDWLSLPFDPSMAPFSISSGGQFPAYEGGGLNFLWNLPS", "output": "Transcription factor; part of the L-tyrosine degradation gene cluster that mediates the biosynthesis of the brownish pigment pyomelanin as an alternative melanin . Acts as a transcriptional activator for the genes of the tyrosine degradation cluster ."}]}
+{"id": "function_test_1123", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRTDGRNNRELRPVHIQPHYIKHAEGSVLIEIGDTRVICTATVEDKVPPFMRGGGKGWITAEYGMLPRATEQRNAREASKGKVSGRTMEIQRLIGRALRSVVELEQLGERTVWIDCDVIQADGGTRTASITGAYVALVLALSKLVAEGKLESLPVRDFLAATSVGIDPEHGVILDLNYSEDARAKVDMNVVMTGAGQFVEIQGTGEEASFSRAELEELLETAQLGIEQLITIQRRVLGEQAALIGEKVEQEGKSE", "output": "Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation."}]}
+{"id": "function_test_1124", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKKTTLLVILDGWGYSDSDYFNAIKNANTPTWDSIWQEFPKTLINASSLEVGLPRSQMGNSEVGHVNIGCGRVVYQELTKIDKAIEEKTFGDNKAICAAIDNVIKNDSNLHLIGLLSPGGVHSHEEHIFEMIKIAKQKGIKRLYLHAFLDGRDTPPRSAEKSIKKADKLLQDLNLGYIASVCGRYYAMDRDNRWDRVEKAYNAIVNANADFIYDSALEALEQSYARDQSDEFVIPTCIKKDGHLVKVQDNDSVIFMNFRADRAREISHAFTDESFDHFPRKKHLNINFTTLTEYDSKLKCAVAFPPKQPINTLGEVLMKNHKTQLRIAETEKYPHVTFFFNGGREEQFEGEDRILIPSPKVATYDLQPEMSAPEVTDKLVAAINSGKYDCIVCNYANSDMVGHTGNYEAAMQAIEYLDKCIARLKDAILEHDGNMFITADHGNADMMVNPETQKPHTAHTTNLVPFIYVGHKKAQVALEHGKLSDIAPTLLNVMGIAQPKEMTGKTIFNFEK", "output": "Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate."}]}
+{"id": "function_test_1125", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPMPPDDSPLSLLPDHPLAAHNTFGIAATARYAARITHAAQFEALHRDPRVASLPQLVLGGGSNVVFTRDFDGVVLLDEIGGRRVVREDDDAWYVEAGGGEPWHAFVAWTLEQGMPGLENLALIPGTVGAAPIQNIGAYGLEMKAYFDSLIAVELATGRSERFDAARCAFGYRDSFFKRDGRGRFAIVAVTFRLPKRWTPRLGYADVTRELDARGIAPDAATPRDVFDAVVAIRRAKLPDPRVLGNAGSFFKNPVIDAAQFDALRARAPDVVSYPQPDGQVKLAAGWLIDQCGWKGRALGAAAVHERQALVLVNRGGATGVDVLALARAIQHDVRVRFGVELEPEPVCL", "output": "Cell wall formation."}]}
+{"id": "function_test_1126", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MILEHVLVLSAYLFLIGLYGLITSRNMVRALMCLELILNAVNMNFVTFSDFFDNSQLKGDIFCIFVIAIAAAEAAIGLAIVSSIYRNRKSTRINQSTLLNK", "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_1127", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKHEKGRSFYIHTFGCQMNQADSAIITAILMDGGFRVAGSQEDADIVILNTCAVRENAVERITHQLQFLRGAKRRKKSLLVGVAGCVPQHLKREMLEMFPVIDFLAGPDTYRNLPALIGDAEEGKRPAALEFRIEETYAGIDPLREVGVGAFVPVTRGCNNMCAFCVVPFTRGRERSQPFSAVMDEVRRVVEKGYGEITLLGQNVNSYADPEEGRDFASLLRAVSREAPGCRIRFTTSHPKDISPDLVDAIADSPNICNHVHLPVQSGSSRMLHRMNRGHGIDEYLETVALLRRRIPGVSLTTDLIAGFCGEEDEDHEATLALLREVRYDNAFMFYYSPRFGTAAWKTLADTVPLAVKKQRLQEIIDLQLSISAECLQEAVGSVVDVLAESESRRSTEQLMGRTGTNRAVVFDRGGARPGDRVSVLISKASSATLTGVNQGVLPAFYS", "output": "Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine."}]}
+{"id": "function_test_1128", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNSLFASTARGLEELLKTELESLGARECQVVQGGVHFEGDTRLIYQSLMWSRLASRIMLPLGACKVYSDLDLYLGVQATDWTEIFAPGATFAVHFSGLNDEIRNSQYGALKVKDAIVDSFTRKNLERPNVDRENPDLRINVWLNKETAHISLDLCGEGLHQRGYRDRAGIAPIKENLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMMATDRAPGLHRGQWGFNGWAQHDDAIWKEVKAEAQVRARKGLADYGSRFYGSDSDARVIERAASNARRAGIGELISFEVKDVAQLTNPLPKGPYGTVISNPPYGERLDSEPALIALHSLLGRSMKDYFGGWNLSLFSGSPELLSCLQLRAERQFKAKNGPLDCVQKNYHLTEKEGDSKPSTVAEDYANRLRKNLKKFEKWAKQEGIECYRLYDADLPEYNVAVDRYADWIVVQEYAAPKTIDAQKARQRLLDIIAATIGVLGIAPNKLVLKTRERQKGTNQYQKMSDKGDFIEVGEYNARLWVNLTDYLDTGLFLDHRIARRMLGQMSKGKDFLNLFAYTGSASVHAGLGGARSTTTMDMSRTYLEWAERNLRLNGLTGRQHRLLQADVLGWLRDTDEQFDLIFIDPPTFSNSKRMEDTFDVQRDHIRLMSDLKRLLRKGGTIMFSNNKRGFRMDNDGLAALGLKAQEISQKTLSQDFARNRQIHNCWLITAV", "output": "Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA."}]}
+{"id": "function_test_1129", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSTATPKVGFVSLGCPKATVDSERILTQLRMEGYEIVPTYQDADVVVVNTCGFIDSAKAESLDAIGEAIAENGKVIVTGCMGVAEDSIRDVHPSVLAVTGPQQYEQVVSAVHEVVPPKTEHNPLIDLVPPQGIKLTPRHYAYLKISEGCNHSCSFCIIPSMRGKLVSRPVGDVLSEAERLVKAGVKELLVISQDTSAYGVDMKYKLDFWNGQPVKTRMLELCEALSSMGVWVRLHYVYPYPNVDDVIPLMAAGKLLPYLDIPFQHASPKVLKSMKRPAFEDKTLARIKKWREICPELTIRSTFIVGFPGETEEDFQYLLDWLTEAQLDRVGCFQYSPVEGAPANDLGLEPVPDDVKQERWERFMAHQQAISSARLQAKIGLEMDVLVDEVDGEGAVARSWADAPEIDGSVFIDSTAVKPGDKVRVRIVDADEYDMWGELV", "output": "Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12."}]}
+{"id": "function_test_1130", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNKPFIDVLAGQRQSVPPIWMMRQAGRYLPEYREVRAKAGGFLDLCFNPELAAEVTLQPIRRFGFDAAIIFSDILVIPHALGRSVRFEVGEGPRLDPLDTPEKISTLSGEADLSKLEAVFEALRRVRSELPQSTALIGFCGAPWTVATYMVAGQGTPDQAPARLLAYRAPEAFQRIIDALVDSSIAYLLKQLDAGADALQIFDTWAGVLSPREFARWSVAPTRRIVEGVRKIRPDAKIIGFPRGAGALLPGYVTETGVDAVSIDWTAEPGLVRERVQSKVAVQGNLDPLALITGGAALDQAVDDVLASYAGGRHIFNLGHGITPETPIAHVEQMLARVRAYKG", "output": "Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III."}]}
+{"id": "function_test_1131", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTTFLAKNWSSLIKPTKVQYEAVDNNPNIKTMVVEPLERGLGLTLGNSLRRVLLSSLRGAAITSIKIPGVEHELSPVSGVKEDLTDIILNIRDVIVKMDSVQKCNLRLEVTGPAVVTAGMITVTDKQDVTILNPQHVICNLSKGFNLEMDLICEQGKGYVPTSCLHNSDSPIGAIHLDALFNPVRRVSYKVENSMVGQMTNYDKLIITVETNGVVNPDAALGLAARILLDQLQVFINFQEVEEEKPEKLELQTINPVLLKKVYELELSVRSQNCLKNENIVYVGDLVARTETQMLKTANFGRKSLNELKKVLANFNLEFGMKDIGWPPDNLESLAKKHEDQY", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_1132", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNWLTNVVRPKIRNILRRETPENLWIKCPDSGQLVFYKDVEANQFVIPGSNYHMRMGATARLKSMFDNETWFDVALPEVTPDPLKFRDERRYADRIKDARARTGMNDAVKVGFGKLEGMGVVIAVQDFDFMGGSLGMAAGEAIVRGLELAVEKTSPFIVFAASGGARMQEGILSLMQMPRTTVAVQMLREAKLPYIVVQTNPTTGGVTASYAMLGDVHIAEPGALIGFAGARVIEQTIREKLPEGFQRAEYLLDHGMVDMVVHRHDLRPTLARLCRLLTKSPAVEHPKPAPQLPPPAKTVEAADAPAVAPTA", "output": "Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA."}]}
+{"id": "function_test_1133", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIGAGLAGSEAAWQLAEAGVDVVLHEMRPDRMTEAHRTATPAELVCSNSFRSDDAANNAVGLLHAEMRRLGSLIMRAADANQVPAGGALAVDREGFSAAVATALNGHPRIELRRGEITGLPPSDWDNVIIATGPLTSQPLAEAIRDLTDETALAFFDAIAPIVHRDTIDMSKAWFQSRYDKVGPGGTGADYINCPMTKDQYDTFVAALLAGEKTDFKDWETNTPYFDGCLPIEVMAERGHETLRHGPMKPVGLTNPHNPTVKPHAIVQLRQDNKLGTLYNMVGFQTKLKYGPQQQIFRTIPGLENAEFARLGGLHRNTFLNSPKLLDAQLRLRAQPRLRFAGQMTGCEGYVESASIGLIAGLYAAAEARGTGLSPPPATTALGALLGHITGGHIETIDGATRSFQPMNINFGLFPPLAVAPTRKPDGSRLKGNEKTVAKKQALSARALADLDGWIAEHLRVAAAA", "output": "Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs."}]}
+{"id": "function_test_1134", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTAKSRILVLNGPNLNLLGLREPTHYGSQTLEQIVATLRDQAQKADIELEHLQSNREYELIEAIHQAFGKVDFIIINPAAFTHTSVALRDALLGVAIPFIEVHLSNVHAREPFRHHSYLSDKAQGVICGLGAQGYEFALSAAIRALQAKQ", "output": "Catalyzes a trans-dehydration via an enolate intermediate."}]}
+{"id": "function_test_1135", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAKTDYYELLGVSRGASADELKKAYRKLAMQYHPDRNPGDAAAEQKFKDINEAYDVLKDEQKRAAYDRFGHAAFENGGGPGAGGFGGGFGGFGGFEGGIGDIFEQMFGEAMGGRRGGRTERAGADLRAAVEIDLTQAFTGTKTEIRVPTRVSCDACSGTGSADKSAANDTCPTCGGAGRVRAQQGFFVVERTCPTCGGAGRTVRNPCRVCSGAGTVPRERTLSVTIPAGVEDGTRIRLSGEGEAGGRGASPGDLYVHVSIRPHPIFQRDGANVFCRVPLRMAQAALGGEIEVPAIDGTRARVKIPAGTQTGDQFRLRGKGFSVLRSTARGDMYIQVAVETPQNLTKRQRELLEEFEREAGNTASGSPEHEGFFAKVKEFFDGL", "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins."}]}
+{"id": "function_test_1136", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSLTLERGAIAPLPVLQDNIIWIWSCGSEAVVVDPAVAEPVIEALQQKGLTLIAVLQTHHHADHIGGTPDLLRQWPDAAVIASGQDRGRIPFQTQPVAAGTRFTLLGVPVDVIDVRAHTSAHLAFFLPEGCSPGGHPPALFCGDTLFSGGCGRLFEGTPDDMHRALQTLATLPESTRIYCAHEYTEGNLRWAHALQPEDRAIKARLEDVIALRTQHKLTIPSTLAEEHRSNLFLRAQSAAELGRLRQLKDDWKGF", "output": "Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid."}]}
+{"id": "function_test_1137", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIEELQDYLAKEFNIHFDNPALLAEAFTQASYVNEHPNQGLKYYERIEFLGDAVLELIVSEYIYKRFPELPQGKLTRLRAAMVCEDSFSKFAKECHFDQYIRLGHGEEMAGARERPGLLCDIFESFIGALYLDQGRPAVEKFVQRVIFPKLDMGWFDHAVDAKTSLQEFLQRDGDIAIEYHLVEESGTENDPEFKVNVTANGDVIGEGKGSSKKHAEMQAAQQALDNMRNKNK", "output": "Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism."}]}
+{"id": "function_test_1138", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNHVKKPDWLKINIGANARYTETKHIVDSHKLHTICSSGRCPNMGECWGKGTATFMIGGEICTRSCKFCNTQTGRPLPLDPEEPTHVAESIQLMKLSHAVITSVDRDDLDDLGAAHWAKTISEIKRLNPETTTEVLIPDFQGKSELIQLVIDAKPDIISHNMETVRRISPLVRSAANYATSLKVIKQIANNGITAKSGIMVGLGERPEEVEEVMDDLLAQGCKILTIGQYLQPTHRHYPVAEYITPDQFKQYRTIGLKKGFREVESAPLVRSSYHAEKHIKFKG", "output": "Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives."}]}
+{"id": "function_test_1139", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGRMFGTDGVRGVANTELTARIAYDLGRAGAYVLTEGAHKPKILVAKDTRISGDMLESALIAGILSVGAEAIVLGVVPTPAVAYLTRKYGADAGVMISASHNPVEYNGIKFFNDKGYKLSDELEDEIQRVIESDFEGVPSPTGTDLGRETIEVSALDDYIEFAKNTIPYSLKGLKIALDCANGAAYKSSVKAFRELGADVFVINDNPDGTNINENCGSTHPEELMEYVIKKKCDLGFAFDGDADRCLAVDEKGNLINGDFILMLCAKYLKELGKLKDDTLVVTVMSNLGLDIACKNEKINIVKTAVGDRYVLEEMVKNKYVLGGEQSGHVIFLDYNSTGDGLVTALQIAGIVKKKEKALSELCSIMKELPQVLANATIPNDKKDLYLTDDEIQNEIRKIEEALNGVGRVLIRPSGTEPLVRVMLEGENQAEIDEMAHNLANLIEKKYN", "output": "Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate."}]}
+{"id": "function_test_1140", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQGRLSAWLVKHGLVHRSLGFDYQGIETLQIKPEDWHSIAVISYVYGYNYLRSQCAYDVAPGGLLASVYHLTRIQYGVDQPEEICIKVFTPRKNPRIPSVFWIWKSADFQERESYDMLGISYDNHPRLKRILMPESWIGWPLRKDYIAPNFYEIQDAH", "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_1141", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIVTRFAPSPTGYLHIGGLRTALFNWLWARKNGGKFILRIEDTDLARNSEEATKAILEAFDWVGLDYDGDVAYQSKRFDIYKRYIQKLLDEGKAYYCYMSKEELDRLREEQMKRGERPRYDRRYRDFTGTPPQGVQPVVRIKAPLEGDIVFEDGIKGIVTIKAEELDDFIIARSDGTPTYNFVVAIDDALMGVTDVIRGDDHLYNTPKQIIVYEALGLPIPRFYHVPMILNEQGKKLSKRDGAMDVMEYKKMGYLPEALLNFLVRLGWSHGDQEIFSLQEMKELFDPKDINKSASAYNLSKLQWLNAHYIKNTPNEKLVKLLEEFGLFLSDHDKKEILLDALKERAKTLQELADMAKEILEAPKNYDEKGVKKALKGEWKAILELFLQKLKASDAHLPSDFHAIIEAVVEEKEIGFGKIGQPLRLALLGKMAGPDLSDVMAIIGKEETIARVEKLIKEKGNS", "output": "Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)."}]}
+{"id": "function_test_1142", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSNKNKSYDYVIIGGGSAGSVLGNRLSEDKDKEVLVLEAGRSDYFWDLFIQMPAALMFPSGNKFYDWIYSTDEEPHMGGRKVAHARGKVLGGSSSINGMIYQRGNPMDYEGWAEPEGMETWDFAHCLPYFKKLEKTYGAAPYDKFRGHDGPIKLKRGPATNPLFQSFFDAGVEAGYHKTPDVNGFRQEGFGPFDSQVHRGRRMSASRAYLHPAMKRKNLTVETRAFVTEIHYEGRRATGVTYKKNGKLHTIDANEVILSGGAFNTPQLLQLSGIGDSEFLKSKGIEPRVHLPGVGENFEDHLEVYIQHKCKEPVSLQPSLDIKRMPFIGLQWIFTRTGAAASNHFEGGGFVRSNNEVDYPNLMFHFLPIAVRYDGQKAAVAHGYQVHVGPMYSNSRGSLKIKSKDPFEKPSIRFNYLSTEEDKKEWVEAIRVARNILSQKAMDPFNGGEISPGPEVQTDEEILDWVRRDGETALHPSCSAKMGPASDPMAVVDPLTMKVHGMENLRVVDASAMPRTTNGNIHAPVLMLAEKAADIIRGRKPLEPQYIDYYKHGVHDENEGAIEVKPYAK", "output": "Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate."}]}
+{"id": "function_test_1143", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSSTAMVSGDDSLEPTLQSLLDQKTLRWVFVGGKGGVGKTTTSCSLAIQLAKVRKSVLLISTDPAHNLSDAFGQKFGKEARLVDGFDNLSAMEIDPNGSIQDLLATGGDQADDPMAGLGLGGMMQDLAFSIPGVDEAMSFAEVLKQVKSLSYEVIVFDTAPTGHTLRFLQFPTVLEKALAKLSQLSSQFGPMLNSILGARGGLPGGQNLDEILSKMESLRETIGEVNAQFKDADLTTFVCVCIAEFLSLYETERMIQELTSYQIDTHCIVVNQLLFPGKDSSCEQCKARRKMQKKYLNEIEDLYEDFNVVRMPMLVEEVRGKEKLEKFSNMLVNPYVPPEE", "output": "ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting."}]}
+{"id": "function_test_1144", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSKNKLSKGQQRRVKANHQRRLKTTAEKADYDDNLFGETSEGIVISRFGMHADVESADGSVHRCNIRRTIRSLVTGDRVVWRPGKDAADGVSVKGIVEAVHDRASVLTRPDFYDGVKPIAANIDQIVVVSAILPELSLNIIDRYLVACEAQDIEPLIVLNKIDLLDDDGLRFVNEQMDIYRNIGYRVLLVSSRTQDGLKPLEAALTDRISIFAGQSGVGKSSLLNALLGLSEDQILTNDVSDVSGLGQHTTTAARLYHFPHGGDVIDSPGVREFGLWHLEAEQITNGFVEFHDYLGRCKYRDCKHDTDPGCALREAVENGKIAESRFENYHRILESMAQVQVKTRKNFSSSDD", "output": "One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit."}]}
+{"id": "function_test_1145", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNKFKGNKVVLIGNGAVGSSYAFSLVNQSIVDELVIIDLDTEKVRGDVMDLKHATPYSPTTVRVKAGEYSDCHDADLVVICAGAAQKPGETRLDLVSKNLKIFKSIVGEVMASKFDGIFLVATNPVDILAYATWKFSGLPKERVIGSGTILDSARFRLLLSEAFDVAPRSVDAQIIGEHGDTELPVWSHANIAGQPLKTLLEQRPEGKAQIEQIFVQTRDAAYDIIQAKGATYYGVAMGLARITEAIFRNEDAVLTVSALLEGEYDEEDVYIGVPAVINRNGIRNVVEIPLNDEEQSKFAHSAKTLKDIMAEAEELK", "output": "Catalyzes the conversion of lactate to pyruvate (Potential). Appears to be the primary factor that allows S.aureus growth during nitrosative stress in both aerobically and anaerobically cultured cells (By similarity)."}]}
+{"id": "function_test_1146", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVSTASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPMSLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKPDGLTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFGKRGRGLYNKARGIDHSEVKSSRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERLNKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRLIGVTVGNLEQSTNKNMTIYDFI", "output": "Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII."}]}
+{"id": "function_test_1147", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQLGLDFNLVEDLVAGVDEVGRGPLCGPVVTAAVILDPSRPILGLNDSKKLSEARREALFEEIREKALAWCVARAEVEEIDRLNILHATMLAMQRAVEGLSVTPRLALIDGNRCPRLAVPSAPVVKGDSQVPAIAAASILAKVSRDREMVELDRLYPGYGMAGHKGYPTAVHLEALSRLGPTPIHRRSFAPVRELLDASVE", "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."}]}
+{"id": "function_test_1148", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKRLWQHCHAATLRNGKYSIVEDAVLVTDGPLIHWIGPRAELPPGDYAERIDLGGAWLTPGLIDCHTHAVFGGNRSGEFEQRLEGVSYAEIATAGGGIASTVRATREASEEELLASARKRLDPLLRDGVTALEIKSGYGLDLASEAKMLRVIRRLGEQLPATVRSTCLAAHALPPEYAGRADDYIGHVCTTILPALAKEGLVDAVDAFCEHLAFSPAQVERVFIAARELGLPVKLHAEQLSSLHGSSLAARYQALSADHLEYMTEEDARAMGAAGTVAVLLPGAFYLLRETRLPPIDALRRHGVAMAVASDLNPGTSPALSLRLMLNMACTLFRLTPEEALAGVTLHAARALGLEASHGSLEAGKLADFVAWEIERPAELAYWLGGDLPKRVIRHAEEVYRG", "output": "Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway."}]}
+{"id": "function_test_1149", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTTEHLSQQRFADLPLHPQILAALNDQNFEYCTPIQALSLPLTLQGKDVAGQAQTGTGKTMAFLTATFHHLLTHQPDFITNQPRALILAPTRELAVQIAHDAESLAQTTKLRIALAYGGDGYDKQLKTIENGVDILIGTTGRVIDYVKQGIIRFNDIQVVVLDEADRMFDLGFIKDIRYLLRKCPAPKSRLTMLFSATLSYKVRELAFEDMNDPEYIEIEPLQKTGHRIKEELFYPSNRDKMALLMTLLEEEWPERCIIFANTKHRCEEIWGYLAADGQRVGLLTGDVAQKKRLALLKQFTDGELDILVATDVAARGLHIPDVTHVFNYDLPDDREDYVHRIGRTGRAGESGMSISFACEQYAMNLPAIEEYIGHHIPVSQYDPDSLINDLPKPYRIKRNHTIPHSSRDYKKR", "output": "DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA."}]}
+{"id": "function_test_1150", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSFDINWSTLESDNRLNDLIRKHLNSYLQNTQLPSYVSNLRVLDFDLGKVGPAITLKEITDPLDEFYDSIREEADQETEENNDNKEDSEHICPDRTIANHEGPKDDFEAPVVMPSPNDIQFLLEVEYKGDLLVTIGADLVLNYPVEKFMTLPVKLSISDIGLHSLCIVACLSKQLFLSFLCDVSDPALDDNQTVLDPKGPILAATKPLERISIVRSMKIETEIGEQYQGQGSVLRSVGELEQFLFTIFKDFLRKELAWPSWINLDFNDGDE", "output": "Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids."}]}
+{"id": "function_test_1151", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPIKKILLLNGPNLNLLGTREPHIYGYDTLASIESSLSTYLSSLTPSVELLTFQSNWEGALIDRIHEARTDGTDAIVINPAAFTHYSVALRDALTGVDIPFVEVHISNVHKREEFRHKSFLSDKAEAVICGLGVFGYRAAVEWCVGYLKERPKL", "output": "Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway."}]}
+{"id": "function_test_1152", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNRRDFIKSAAASAACASAGIAIPANLSAASEAEKGWRWDKAACRFCGTGCGIMVATKEGKIVAVKGDPEAPVNRGLNCIKGYFNAKIMYGEDRITHPLLRVNEKGEFDKKGKFKQVSWKQAFDVMEAQFRKTYDELGPHGVGVLGSGQYTIPEGYTAAKMMKAGFRSNSIDPNARHCMASAVVGFIQVFGIDEPSGCFDDIELTDTIVAWGANMAEMHPILWARVSDRKLSNPDRVKVVNLSTYSTRTSNLADIEIIFAPSADLAIWNYIAREIVYNHPEMIDEEFVKKHCIFTTGPADIGYGLRPDIKYKKYLSSELDTAATEKSKVLSEAEGVTLSYLGLKAGDTMENKNTATAGNHWHISFEEFKKALAPYTLEFTAKVAKGDPNEDIEEFKGKLKALADLYIEKNRKVVSFWTMGFNQHQRGTWVNEQAYMVHFLLGKQALPGSGAFSLTGQPSACGTAREVGTFVHRLPADMVVNNPKHREISEKIWKLPAGTLNGIPGSHYVKMMRDLEDGKVKFIWVQVNNPWQNTANANHWIKAAREMDNFIVVSDPYPGISAKVADLILPTAMIYEKWGAYGNAERRTQHWRQQVLPVGEAMPDIWQMLEFSKRFKLKDVWGEKKLNDKVTLPSVLDAAKAMGYSEEDTLFDVLFANEEAKSYPANDPIMENFDNTEVFGDKRGVIGSDGKEFKGYGFFVHKYLWEEYRKFGLGHGHDLADFDTYHRVRGLRWPVVDGKETQWRFNTKFDPYAKKAAPNDKFAFYGNKAAALPSGDLKGVTDKEKTPLTNKAKIFFRPYMDPCEMPSSEYPFWLCTGRVLEHWHSGTMTMRVPELYRAVPEALCYMHEQDAAKLGVLQNEIVWIESRRGKVKARVDLKGRNKPPVGLVYVPWFDENVFINKVTLDSTCPISKETDYKKCAVKIYKA", "output": "Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite."}]}
+{"id": "function_test_1153", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKNIRNFSIIAHIDHGKSTLADRLIQECGAVSSREMSSQIMDTMDIEKERGITIKAQSVRLNYTLDGQNFVLNLIDTPGHVDFSYEVSRSLASCEGALLVVDASQGVEAQTIANVYIALENNLEIIPVINKIDLPAADPQRVKDEIEHVIGLDCSGAIEVSAKTGAGINELLEAIVRRVPAPDANDALPTKALIYDSWFDNYLGALALVRIYDGEIKKNDEVLVMGTNKKHIVLDLMYPHPIAPIKTARIGTGEVGIIVLGLKNVSDVQVGDTITLAKNPTKEPVGGFERAKPFVFAGIYPIETDKFEDLRDALDKLKLNDSSISYEPETSIALGFGFRVGFLGLLHMEVIKERLEREFDLDLIATAPTVTYEVVQTDGQILRIQNPSQLPAVNKIEMIKEPYVRSTIITPTEFLGNIITLLNNRRGVQTKMDYITPERVLLEYDIPMNEIVMDFYDKLKSSTKGYASFDYEPSDYREGDLVKLDIKVAGETVDALSIIVPESKAQSKGRDFVKAMKEIVPRQLFEVAIQASIGNKIIARETVKSMGKNVTAKCYGGDITRKRKLLEKQKEGKKRMKAIGKVNLPQEAFLSVLKID", "output": "Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner."}]}
+{"id": "function_test_1154", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIKIGIYGAKGRMGKQIEECLKSETQAEISILYNKGGNLEELFEKSDVIIDFSSPSGTHELLNYARTMPKPLTIGTTGLDEKILHLMQSASKVMPIFYATNMSLGVAVLNYLASKASQMLRNFDIEILEMHHRHKKDAPSGTAMTLAQSVAKARNLELEKVRVSGRDGIIGERSKDEIAVMSLRGGDIVGRHTVGFYEDGEFLELNHTATSRATFAKGAIKIAIWLSKQEAKMYSINDFFRNLKCVQL", "output": "Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate."}]}
+{"id": "function_test_1155", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRVYYDRDADLNLIKGKKVAVVGYGSQGHAHALNMRDSGVKEVVVALRPGSATAKKAEAEGFKVMSPADAAKWADVVMMLTPDELQGDIYRESLADNMKHGAALLFAHGLNVHFNLIEPRPDLDVLMVAPKGPGHTVRSEYQRGGGVPTLIAIAQDASGNAHDLGLSYASAIGGGRAGVIETTFKEECETDLFGEQVVLCGGLVELIRAGFETLVEAGYAPEMAYFECLHEVKLIVDLIYEGGIANMNYSISNTAEYGEYVTGPRIITPETKAEMKRVLTDIQTGKFTRDWMLENKVNQASFKATRARANAHPIEEVGEKLRAMMPWIKAKALVDKTKN", "output": "Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate."}]}
+{"id": "function_test_1156", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRKILVTNALPYANGDLHLGHMLGYIQSDIWVRFQKLQGNQCIFVCGSDTHGTPIMLKAKSLGITPEELVTKYSNRHLQDFTDFEINFDNYHSTHNSLNKEIVEDIYNKLNNKNLISKKAIAQAYDPEAKMFLPDRFVKGTCPKCKAEDQYGDSCEVCGATYDPTELINPRSVISGQSPIQKNSEHFFFDLPALEKNIKDWIESNTLLQPEVANKLAEWFEQGLQSWDISRDAPYFGFAIPGTNEQKFFYVWLDAPMGYIASFKDYCNKNNINFGDFWGDSSSESELYHFIGKDIIYFHALFWPAILSSTGYKTPTSVFANGFLTVNGKKMSKSRGTFIQARTYLDNLEPSYLRYYFASRLTSRIDDIDLNLEEFVTKSNSDIVGKVVNIASRCAGFIYKKFDATLSGEIFDPELESEFSKNHDAITQAFEKREFAHAVRLIMALADKANQFIDYHKPWQLAKEEGQEQKVHQVCSQGINMFKVLIAYLKPIIPSIVAEAERFLNIQFISWADAPKFLINHKIDKFKPLATRIEKEKVDKILEDTKKMFENEQAPQSKKEEPKLDIAAECTFDDFMKVDLRIAKITEASHVEGADKLLKLILDLGGVTKQVFAGIKSAYKPEDLIGKHTIMVANLAPRKMKFGMSEGMVLAAGDGKGIYILEPHEGAQPGMRVK", "output": "Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation."}]}
+{"id": "function_test_1157", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGQTPVLARVHSECLTGDALFSLRCDCGFQLEAALTHIAEEGRGILLYHRQEGRNIGLLNKIRAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVDEVRLLTNNPKKVEILTEAGINIVERVPLIVGRNPNNEHYLDTKAAKMGHLLGK", "output": "Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate."}]}
+{"id": "function_test_1158", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSQDYYQILGVSKTASSAELKKAYHKLAKQYHPDNAAAGDTNAEKKFKEINAAYDVLKDEQKRAAYDRFGHDAFQNQQSRRGAGGGTSSFHPDINDIFGDFFSDFMGGSRRSRPTSSKVRGSDLKYDLTINLEEAFHGIEKNISFSSEVQCDTCHGNGSEKGETITTCDACSGVGVTRIQQGFFTIEQTCHKCQGNGQMIKNPCKKCHGMGRYHKQRNLLVNIPAGVENGTRIRHTGEGEAGIRGGNSGDLYVDISIKPHDIYKVDGANLHCKLPISFVNAALGGEVEVPIIEGGKVNLTIPAGTQNGDQLRLRSKGMSKMRSTIRGDMLTHIHVEVPKNLSKRQRELLEEFKKESMSEKENDSSFFNKMKSLWS", "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins."}]}
+{"id": "function_test_1159", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEIILGVAMFTGIVMVLVLLILFAKSRLVNTGDIAVEVNGDLDKSFTAPAGDKLLNMLSSQGIFVSSACGGGGSCGQCRVVIKEGGGDILPTELSHINKREAKEGCRLACQVNVKQNLKIELPEEIFGVKKWECEVISNDNKATFIKELKLKIPDGEDVPFRAGGFIQIEAPAHDISYADFDVPDEYRGDWDKFNLFRYRSVVNETTVRAYSMANYPDEKGIIMLNVRIATPPPRDPDVPPGIMSSYIWSLKAGDKVTISGPFGEFFAKDTDAEMIFIGGGAGMAPMRSHIFDQLNRLKSKRKITFWYGARSLREMFYEEDFNQLQAENENFTWHVALSDPQPEDNWTGYTGFIHNVLLENYLRNHPAPEDCEFYMCGPPMMNAAVIKMLKDLGVEDENIMLDDFGG", "output": "NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway."}]}
+{"id": "function_test_1160", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSKQRKLTEADVTPESVFYQRRKVLQALGITAASLALPHNAQADLLSWFKGNDRPKAPPGKPLEFSKPAAWQAQLDLTPEDKVTGYNNFYEFGLDKADPAANAGGLKTEGWQVRIDGEVAKPITLDIDDLIKRFPLEQRIYRMRCVEAWSMVVPWIGFELGKLIKFAEPNSNARYVAFQTLYDPEQMPGQKDRFIGGGLKYPYVEGLRLDEAMNPLALLTVGVYGKTLPPQNGAPLRLITPWKYGFKGIKSIVHIRLVRDQPPTTWNQSAPNEYGFYANVNPHVDHPRWSQATERFIGSGGILDVKRQPTLLFNGYAEQVASLYRGLDLRENF", "output": "Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide."}]}
+{"id": "function_test_1161", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIPNTPSITPELVAEHGLKPDEYQRFVELIGREPTITELGIVSAMWNEHCSYKSSKVWLRTLPTKGPRVIQGPGENAGVVDIGDGLAVVFKMESHNHPSFIEPYQGAGTGVGGILRDVFTMGARPIAALNALRFGDPHHPRTRRLLAGVVAGIGGYGNSFGVPTVGGSVGFHERYNGNILVNAMAVGLAKTDEIFYAAAAGVGRSIVYLGSKTGRDGIHGATMASAEFGADAEEKRPTVQVGDPFAEKLLLEACLEIMQAGCVVAIQDMGAAGLTCSAVEMGAKGDLGVELDLNAVPCRETGMTAYEMMLSESQERMLMVIADGKEDQAEAIFRKWGLDFAIIGKTTDTLRFVVKHDGDVKADLPIKELGDEAPEYYRPFTETPPRPVLGPSDVNHAVSVADALERLIASPDLCSKRWVWEQYDHLILGNTVQRPGGDAAVVRVNEGPKALALTTDVTPRYCEADPFEGGKQAVAEAWRNLTAVGATPIAVTDNLNFGNPEKPEIMGQFVGCVKGIGAACEALDFPVVSGNVSLYNETNGQGILPTPTIGGVGLIDDVEQSMTLAFKAAGEAIFVVGKTDGWLGSSAYLYTVCDREDGAPPPVDLVAEKRNGDFVRGLIKDDFITAAHDVSDGGLLVAIAEMAMAGRIGASVDGVPAGMPAHSFWFGEDQARYVVTLPANQAAEMVRRAEAAGVPVTKLGKTGGDKITLANERPIFVEGLRDRHDSWLPIYMGAN", "output": "Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL."}]}
+{"id": "function_test_1162", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSASDLTSVQAAAPQGRRQILVTSALPYANGQIHIGHLVEYIQTDIWVRTLRMHGHEVYYIGADDTHGTPVMLRAEKEGLTPKQLIERVWAEHKRDFDSFGVSFDNFYSTDSEENRQLSEKIYLALKDNGLIAEREIEQAYDPVKEMFLPDRFIKGECPKCHAKDQYGDSCEVCGSTYLPTELLNPYSVVSGATPVRKTSKHYFFRLSDPRCETFLREWVSGLAQPEATNKMREWLGDAGEAKLADWDISRDAPYFGFEIPGAPGKYFYVWLDAPVGYYASFKNLCDRKGIDFDAWIRAGSSAEQYHFIGKDILYFHTLFWPAMLQFSGHRTPTNVFAHGFLTVDGAKMSKSRGTFITAQSYIDTGLNPEWLRYYFAAKLNATMEDIDLNLDDFQARVNSDLVGKYVNIASRAAGFLIKRFDGRVQDSAMNHPLVAKLREAIPQIAAHYEAREYGRALRHTMELADEVNAYVDGAKPWELAKDPANAVALHETCSVSLEAFRLLSLALKPVLPRVAEAVEAFFGIAPLAWADAAKPLSSAQPIKAYQHLMTRVDAKQIEALLAANRDSLQADATAAGGAGAATAKGAKAAKADAKPVSAKAPAANGADDATISIDDFAKIDLRIAKIVACQAVEGSDKLLQLTLDVGEEKTRNVFSGIKSAYQPEQLVGKLTVMVANLAPRKMKFGLSEGMVLAASATDEKAEPGLYILEPHSGAKPGMRVK", "output": "Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation."}]}
+{"id": "function_test_1163", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MHKDEDQRLLGPAPLPNDPDRSLRPQVLDDFIGQEAARANLKIFIEAAKTRQEALDHVLFVGPPGLGKTTLSQIMAKELGVNFRSTSGPVIAKAGDLAALLTNLEERDVLFIDEIHRLNPAIEEILYPAMEDYQLDLIIGEGPAARSVKIDLAKFTLVAATTRLGLLTTPLRDRFGIPIRLNFYTIEELEYIVQRNARLFAVKISDDGAHEIARRARGTPRIAGRLLRRVCDFALVKQAKQIDRKIADEALSRLEVDHLGLDPLDRRYLLLIAETFLGGPVGIETIAAALSEPRDAIEDIVEPYLLQQGFIQRTARGRILTEKAWSHLGLAAPASTSIQKRTQLSDAQDNVSLQTTLWDGEDD", "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA."}]}
+{"id": "function_test_1164", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTTEKRQILVTAALPYANGPIHLGHMVEHIQADIWVRFQRLKGNDCLFICGEDAHGTAIMITAQKQGLPPEALVAKMHKEHARDLGGFLIEYDNFYTTHSPENRELAELIYTRLKDKGDIFAKTISQAYDPVKEIFLPDRFIRGTCPRCGAKDQYGDVCEVCGATYSPTELIDPVSALSGAKPIEKNSEHFFFSLNRYTQLLKKWIDAGHLQPQVANKLKEWFSEDLKPWDISRDAPYFGFEIPHAANKYFYVWLDAPIGYMASLKNLSKQRPSVNFDAYWKEGSQTELYHFVGKDIVYFHALFWPAMLSGAGFRLPTTIYVHGYLTVNGQKMSKSRGTFITAHHYLDHLSPEYLRYYYAAKLSAQVEDIDLNLDDFIQRVNADLIGKYVNLASRCAGFITKNFGGKLANELPEPDLYESFLQTEQTITDYYESLNYSKAVRVIMSLADRANQYIDAKKPWALAKEINQEAQVQAVCTQGLNLFKILTTYLKPILPVTAKKVEQFLNCDELNFANLKTPLLDHSVNPFEPLMQRLLPETAAQLTHE", "output": "Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation."}]}
+{"id": "function_test_1165", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSTQLRAAEISDIIESRIEKFGIKAEERTEGTILNIKDGIVRVYGLRDVMFGEMVEFPENTYGLAFNLERDSVGAVVMGPYEHLEEGMTARCTGRILEVPVGEALLGRVVDGLGKPIDGKGPIDTSETSPIEKVAPGVITRKSVDTSLPTGLKSIDAMVPIGRGQRELIIGDRQTGKTAIAIDTIINQKHTGVKCIYVAIGQKQSSVAAVVRKLEEHGAMEHTIVVNASASEAAALQYLAPYAGCTMGEYFRDRGQDALIVYDDLTKQAWAYRQISLLLRRPPGREAYPGDIFYLHSRLLERAAHVNEAYVKEFTKGKVTGKTGSLTALPIIETQAGDVSAFIPTNVISITDGQIYLDVNLFNAGIRPAINAGLSVSRVGGAAQTKIIKKLIGGLRIALAQYRELEAFSQFASDLDEATRKQLEHGQRVMEILKQPQYQPLSVGEMAIIWYVVNNNYLDQVELKKVVDFERSLLSFLRDQHQDLLDEINKNPNYSEKIIEKIKAVVEEFVKTQSY", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit."}]}
+{"id": "function_test_1166", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDRSPLFLIIMGAPGSGKGTQSKLLASQLSLLHISSGDLLRGAVSKDTPLSQEIKSYLDQGKLLPDTLVWKLVHEKLDEFQQDTLLRRLSFLSRSENSAILDGFPRTVTQAKLLHEFLSSYFPNYKVILLDISDEEVLNRLTSRYICPACQGIYNEQQGFSSCPKCSVELIRRSDDTLEVILDRIQTYKQETQPVLDYYTEKQKLITIDANAPTQQVFQSILDSLSASLVYQERDCCNCDCDDED", "output": "Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism."}]}
+{"id": "function_test_1167", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAVTIHQLRTWKEQGRPISVLTAWDFPFATLLDQAGVDVLLVGDSLAMVALGYPTTLPLTLDEMLYHAQAVTRGVNHALVICDLPFLSYQESPQQALRSAGTLLQQAGVAAVKLEGGYPDMAKTVHYLVDRGIPVMGHVGLTPQSVHQFSGYRRQGTSDVEADRILQEAIALEAAGAFAIVLEHIPAPLATKITQTLTIPTIGIGAGPGCDGQVLVTADMLGLSAWQPPFAKAYTNLQESITGAVQQFCDDVRHHQFPQ", "output": "Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate."}]}
+{"id": "function_test_1168", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MERTFLMIKPDGVQRNLVGEIIQRFETKGFTLVGLKMMQVSSELAEKHYAVHKERPFFRSLVDFITSSPVVAMVWQGEGVIASARKIIGATNPLNAEPGTIRGDFGISVGRNLIHGSDGPDTAKDEVSLWFSDAELANWTPAITPWVVE", "output": "Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate."}]}
+{"id": "function_test_1169", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MYAVLTAIIAYLIGCINNAYIFTKYTRNIDIRNYGSGNAGATNVLRVLGYKAAAPVFALDVLKGVIAVLIGKYLMGNTGAMIAGIAVVCGHNWPVFLKFRGGKGIATSVGVVMTVSPLLGLIALAIGVTVIVLTKYVSLGSITGSVTFVLLNAIFWNSTQIFIFSLILASLAIFQHRSNIKRLLAGTESKLGQKTEIK", "output": "Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP."}]}
+{"id": "function_test_1170", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTHTNGFDALHAHAQRLRGAAIPALLAAEPQRPTQYARQVGPLYFNFARQKYDRAALDALFAIARERDLAGAFQRLFRGEQVNVTEQRAALHTALRGDLTDAPVASDAYATAAEVRQRVGALIQQLEGTDVTDIVSVGIGGSDLGPRLVADALRAPSGARFRVHFVSNVDGAAMQRTLATLDPARTAGILISKTFGTQETLLNGSILHAWLGGSERLYAVSANPERAAKAFDIAPGRVLPMWDWVGGRYSLWSAVGFPIALAIGFERFEQLLDGAAQFDAHVLNTPLEENVAVLHGLTAVWNRNLLGSATHAVMTYDQRLALLPAYLQQLVMESLGKRVKLDGAAVDSDTVAVWWGGAGTDVQHSFFQALHQGTSVVPADFIGTVHNDDPYAENHVALMANVLAQTEALANGQDSSDPHRSYPGGRPSTVILLDALTPQALGALISMYEHSVYVQSVMWGINAFDQFGVELGKQLASQLLPALKGEAADVADPVTRELLAKLRG", "output": "Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate."}]}
+{"id": "function_test_1171", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKEISNIKVKIESGTKYTTDHGFHAVKDGIRNKKENSVHIRKPEWLKVKKQDSKEYLKVKSITKKHRLSTVCEEAKCPNINECWSHGTATIMLMGAVCTRACKFCSVDTGNPKGWLDKEEPQNTAESVKLMNLEYVVLTSVDRDDLVDGGAGHYAATITAIKNLDENIKVEALTPDFAGVKENVDKIINTKVDVIAQNIETVERLTHPVRDPRAGYWQTLEFLRYVKQKSPNILTKTSIMVGLGETDEEIYKTMDDARSVGVDIITLGQYMQPTKHHLSVERFVTPQQFEEYRRVGLEKGFLEVASGPMVRSSYRADRVFKRNNLDL", "output": "Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives."}]}
+{"id": "function_test_1172", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIRIGHGFDVHAFGGEGPIIIGGVAIPYEKGLVAHSDGDVALHALTDALLGAMALGDIGKLFPDTDIQYKGADSRRLLRTAYQAILDKGYQVGNVDITIIAQAPKMRPYIDSMRTVIAQDLHCDIEQVNVKATTTEKLGFTGRSEGIACEAVVLLIKQNGTK", "output": "Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)."}]}
+{"id": "function_test_1173", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDYLEWRHVFRLDPAKDISDEDLEKICESGTDVILVGGTDNVTLDGVLDLLVRVRRFEVPIALEISTIDAITPGYDYYFIPTVLNSDDPKWIKNLHHAAIKEFGDIMVWDELVAEGYCILNPDCKVAHVTGATTDLSIDDIVAYARMAENFFKLPVFYLEYSGIYGNPEVVSAVKNELKHTKLFYGGGITSAKQAEEMAQYADTVVVGNIIYEDLKAALATVKAVKNTL", "output": "Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales."}]}
+{"id": "function_test_1174", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPTINQLVRKPRKSKVEKPKSPALNVGYNSHKKVQTNVSSPQKRGVATRVGTMTPRKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKDLPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA", "output": "With S4 and S5 plays an important role in translational accuracy.; "}]}
+{"id": "function_test_1175", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNQFKVISKFNPTGDQPKAIKSIAKGIEKREKFQTLIGVTGSGKTFTMANIIEKVQKPTLVLAHNKTLAAQLCSEFREFFPNNAVEYFVSYYDYYQPEAYVAQSDTYIEKDASINDEIDKLRHSATSALFERKDVIIVASVSCIYGLGNPEEYKKLTISLREGMEKDRDEIIKKLVEIQYERNDIDFSRGTFRVKGDVLDIFPASSSSKAVRVEFFGDEIDRIKEFDVLTGETITKLKHISIFPASHFATSKDRLEVAIKDIEEELEERVKELVSQDKILEAQRLKQRTNFDIEMMREVGYCTGIENYSRVLDGRAKGTPPQTLLDYFPQDFLLFIDESHVTLPQVKAMQAGDKSRKDSLVEYGFRLPCAYDNRPLTFKEFENKLNQVVFVSATPAKYELEYSTNTAEQVIRPTGLLDPEIIVKPVKGQIDDLYTSIQETIKRGFRILVTTLTKKMAEDLTDYLKEMGVKTRYLHSDIDTIERMKIIHDLRKGEFHVLVGINLLREGLDIPEVALVTILDADKEGFLRSETSLIQTVGRAARNSESKVIMYGDVITKSMEKTIKETNRRRKIQMEYNEEHGIVPKTIIKDIREVIQISDIAEERKEYDNLNEALKSYNNDIDKLIEKYEEEMKEAAQNLQFEKAAHLRDVIYKLKKDKETEL", "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage."}]}
+{"id": "function_test_1176", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGKLGAYVEISRPKNALMSILGTLTGWVNSTSVYDGRLILACLIPPLVLMAGNAINDYYDAEIDAINKPYRPIPSGRISKREALNIYIALSLFGIALSIFLGFIEFLIVTAFSLSWYAYARWLKRTGVPGNALVSLGVAFTLIFGSLAAGNLTNKVIIFSSVAFTSNLIREFVKAVEDLPGDRAHGVRTIAVRIGVKRTGILVFLLSLATVVLTILPVIFRLTGIIYLSLSVIISLPILMLASAICLKGKLEERARETSSLIKVSMFLGLLGMLLDPFRVV", "output": "Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids."}]}
+{"id": "function_test_1177", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGEISPLPGFSQETWEEAQSVLLAWVNNWLAGDCELPQMPSVAFGVSCALAELTDTLPQAANYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRLDANRAWTPLKGQQFAKYVNPDYRDRIAFLEEPCKTRDDSRAFARETGIAIAWDESLREPDFAFVAEEGVRAVVIKPTLTGSLEKVREQVQAAHALGLTAVISSSIESSLGLTQLARIAAWLTPDTIPGLDTLDLMQAQQVRRWPGSTLPVVEVDALERLL", "output": "Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB)."}]}
+{"id": "function_test_1178", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKRLNERSRMVTEGVARAPNRSMYYAIGYEEKDFVKPMVGVANGHSTITPCNSGLQKLADAAVSALEGAGAKAQMFGTPTVSDGIGMGTEGMKYSLVSREVIADSIETCVNGLWQDGVVVIGGCDKNMPGGMMALARTNVPGIYVYGGTIKPGHYKGKDLNIVSAFEAVGEFTSGRLSEEDLKGVEQHACPGSGSCGGMYTANTMSSAFEALGMSLPYSSTMANEDAEKVASTHDSAVVLVEAIKKNLRPRDIITKKSIENAVSVIMAVGGSTNAVLHFLAITSAAEIDWTIDDFERIRKRVPVIVDMKPSGTYLATDLHQAGGIPQVMKILLDDGLLHGDCMTITGKTVAEVLKDVPSVPRADQKVIRTLDNPLYKQGHLAILKGNISPEGCVTKITGLKNPSITGPARVFDSEDDAMAAIMAQKIKDGDIVVIRYEGPKGGPGMREMLAPTSALVGQGLGESVGLITDGRFSGGTWGMVVGHVAPEAYVGGTIALIHEGDSVTIDAHKLLIQLNVDDAEIAKRRAAWKQPKPRYTRGLLAKYAKLASTASKGAVTDLNLND", "output": "Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively."}]}
+{"id": "function_test_1179", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSLITDIYAREVLDSRGNPTVEAEVYTEAGGVGRGIVPSGASTGEHEAVELRDGDKDRFGGKGVLKAVANVNNVIAKEIVGMEVTDQIAIDKAMIALDGTPNKGKLGANAILAVSLATARAAADELQVPLYNYLGGFNAHVMPTPMMNVINGGAHSDNKVDFQEFMIMPVGAPTVREAIRMGSETFHALKKALEADGKVTSVGDEGGFAPDFANNEEPFEYLIKAIEAAGYKPGKDVAIAFDVAASELWNDEDKKYKLHWSTGEEYTTEEWIEYLSDIIAKYPVVSVEDPIDENNWDDWVTLTNKLGKKVQLVGDDFFVTNTDYLAKGIKMGAANSILIKLNQIGTLTETVEAIEMAKEAGYTAIVSHRSGETEDTTIADLVVATNAGQIKTGSMSRTDRLAKYNQLMRIEDNLGDVAKYKGIRSFYNLSEQAKQDIENR", "output": "Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis."}]}
+{"id": "function_test_1180", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTAPPSLQAKAVGIGMTSQRVRDRLVERLRECGIQDERVLSTIRIVPRHLFIDEALALRAYEDTALPIGHGQTISQPWVVARMTEAVMQVVPKKILEIGTGSGYQSAILASLGLEVYTIERIGKLLRQARKRFRQLGIKIRSKHDDGSTGWTEHAPYNAILVTAAAPTLIDTLIEQLAIGGRLVAPVGTASEQALVQLTRTIDGSITHEILEPVTFVSLLPGMLD", "output": "Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins."}]}
+{"id": "function_test_1181", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPVITLPDGSQRHYDHAVSVLDVALDIGPGLAKACIAGRVNGELVDASDLIESDAQLAIITAKDAEGLEILRHSCAHLLGHAIKQLWPDTKMAIGPVIDNGFYYDVDIEHTLTQEDLALLEKRMHELADKDYDVIKKKVSWQEARDTFAARGEDYKVAILDENISRDDRPGLYHHEEYVDMCRGPHVPNMRFCHHFKLQKTSGAYWRGDSKNKMLQRIYGTAWGDKKQLNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELETFVRMKLKEYQYQEVKGPFMMDRVLWEKTGHWENYAEHMFTTSSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGALHGLMRVRGFTQDDAHVFCTEEQVRDEVNSCIKMVYDMYSTFGFEKIVVKLSTRPEKRIGSDELWTRAEDDLAAALTENGIPFDYQPGEGAFYGPKIEFTLHDCLDRAWQCGTVQLDFSLPGRLSASYIGENNDRQVPVMIHRAILGSMERFIGILTEEYAGFFPTWLAPVQVVVMNITDSQSDYVQQVTKKLQDAGIRAKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKIAVRTRRGKDLGSLDVNVVVDQLLAEIRSRSLHQLEE", "output": "Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr)."}]}
+{"id": "function_test_1182", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSKDFILAVDQGTTSSRAIIFDKKGNIRKIAQKEFTQIYPKSGWVEHDAMEIWGTQSGVMREALEFGRVKPDQIAAIGITNQRETVIVWDKETGDPVYNAIVWQCRRTSSICDEIKRDPQFVKYIKENTGLVVDAYFSGTKVKWILDNVEGAREKANAGKLLMGTIDTWLIWNLTRGKVHATDYSNASRTMLFNINSLEWDKKILDYLNIPESMLPEVKNSSEVFGVTDSHTLGGAEIPIAGVAGDQHAALFGHCCFEKGMAKNTYGTGCFALMNVGDKPVYSDEGLLTTIAWAENGKPTYALEGSVFIAGAVIQWIRDGLGLVRSAEDSEYYATKIDSTNGVYLVPAFVGLGTPYWDMYARGTIVGITRDTKREHIIRAALEAIAYQAKDVLECMKEDTGLDLAGLRVDGGAVQNNFLMQFQSDILQSEISKPKINEITGLGAVFLAGLAVGFWKDKQELKSILTTEKVFEPQKDSQAVAHDYRGWKKAVERSKAWAECYS", "output": "Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate."}]}
+{"id": "function_test_1183", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MHDKVLILDFGSQVTQLIARRVREAHVYCEIHPNDVSDAFVREFAPKAIILSGSHASTYEDHQLRAPQAVWDLGVPVLGICYGMQTMAVQLGGKVEWSDHREFGYAEVRAHGHTRLLKDIQDFATPEGHGMLKVWMSHGDKVTELPPGFKLLASTPSCPVAGMADEARGYYAVQFHPEVTHTVQGRALLERFVLEIAGAKPDWVMRDHIDEAVKAIREQVGDEEVILGLSGGVDSSVAAALIHRAIGDQLTCVFVDHGLLRLDEGKMVMDMFAGRLHAKVVHVDASEQFLGHLAGVTDPEAKRKIIGREFVEVFQAEAKKLSNAKWLAQGTIYPDVVESGGTKTKKATTIKSHHNVGGLPETLGLKLLEPLRDLFKDEVRELGVALGLPHEMVYRHPFPGPGLGVRILGEVKREYADLLRRADAIFIEELRGTKATAQDAAAGLCGEGDVGKSWYDLTSQAFAVFLPIKSVGVMGDGRTYDYVTALRAVQTTDFMTAHWAHLPYALLGRVSNRIINEVRGLSRVVYDVSGKPPATIEWE", "output": "Catalyzes the synthesis of GMP from XMP."}]}
+{"id": "function_test_1184", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNRYKFNDIENRLGVYFNNPSLIKTALTHSSFGNQFKDAKYNERLEFLGDSVLQLCITEYLFNKFKDKSEGELTKIRSLIVCENSLYEIAKKLSLGEYIRMSKGEELTGGRERMSIQADAVEAVIAAVYLDKGIGFVNDFILLHFEEMINKAINNEIVLDFKTKLQELLQKDGEILIQYELLKYEGPPHRRKFFTNVIINEKVMGIGEGYSKKEAEQNAAKEALKRLEKNYE", "output": "Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism."}]}
+{"id": "function_test_1185", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKTIFLVGGGTGGHLFPAIALGEELQERGYNVYLITDTRCEKYLLNSNYSFKIHIMNMVSISNTGIKKLYAYIRILAACITGFKLVYSNSPGLIVTFGGYTIAPIIINGILFKIPFILHEQNSVLGLANRLFLRYAKAITVTFANTLNLNNRYKHKVIVTGTPVRKALRFTPKRNFNSKNFQLLVIGGSQGTEIFSTLVPNAIKLLVNCDHDFKITIVHQAVAKDINYVKAMYTELNIEHEVSDFFYNIADKYKNSHLAICRAGASTISEIISLCQPAILVPYPISAQNHQLFNAKAIADNKAGWCIEQSTITPHILFEKIFTLMQSPTLLASTELKLREMKINAENLLANAVEKFIVT", "output": "Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II)."}]}
+{"id": "function_test_1186", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQQLSLLDSVVIPDTAQLRAAELRRLLEHHNRCYYELDSPEISDAEYDALFRELQVIEAARPDLLTPDSPTLRVGGKPLARFSQVRHRMPMLSLENAMQEDEIRGFEQRIRSLLALPDTVALQYQCEPKMDGLAVELVYQDGLLVQASTRGDGEVGEEVTANIRTVRNVPLRLTGDNLPALLEVRGEVYLPLAAFQQLNQQREEAGEPPFANPRNAAAGSIRQLDPAVVARRPLAMVCYGVGVMETEARTQTELMSQLAAWGLPVSDQARQVSGIEGAIACFQDLQERRDSLLYEIDGMVIKVDDLRLQQELGEKSRSPRWAIACKFPPRQATTRINEIILSVGRTGVITPVASLEPVELSGVTVSRATLHNWDEIRRKDIRVGDRVIVERAGDVIPAVVKVLLDKRSGTEQELPEPETCPVCGSRAAREAGEVAVRCQGGLACPPQLAESIIHFASRDAMDIDGLGSKYIEQLISLGLVKDIADLYRLTRDDFMQFERMGDKLAENLLAAIASSKQQELSRFIFALGIRHVGERTARTLAERFGSIDNLQTATLEELTSIRDVGPAVAISIRSFFDAPANQTVLQRLKAAGVAPTVEEKRVGGRLAGLTFVFTGTLATLGRDEAKKLVEAEGGNVTGSVSKKTDYVVAGSEAGSKLEKARNLGITVLSEDAFSKLLATGGNQ", "output": "DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA."}]}
+{"id": "function_test_1187", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVLEYQQREGKGSSSKSMPPDSSSTTIHTCSEAQTGEDKGLLDPHLSVLELLSKTGHSPSPMGQNLVTSIDISGNHNVNDSISGSWQAIQPLDLGASFIPERCSSQTTNGSILSSSDTSEEEQELLQAPAADIINIIKQGQEGANVVSPSHPFKQLQKIISLPLPGKEKTPFNEQDDDGDEDEAFEEDSVTITKSLTSSTNSFVMPKLSLTQKNPVFRLLILGRTGSSFYQSIPKEYQSLFELPKYHDSATFPQYTGIVIIFQELREMVSLLNRIVQYSPGKPVIPICQPGQVIQVKNVLKSFLRNKLVKLLFPPVVVTNKRDLKKMFQRLQDLSLEYGEDVNEEDNDDEAIHTKSRSYCRNKKAENSKKKSPKSNKKPKRKKQKFFTSWFTWGISITIGISFGCCVTYFVTAAYEHQTVKSLSLRPSILASLLSLDSSSDTINTPATASPSSTEQFLWFDKGTLQINFHSDGFIMKSLTIIKETWGKMNTFVLHALSKPLKFLENLNKSSEFSIDESNRILALGYILL", "output": "Mitophagy-specific receptor that recruits the autophagic machinery to mitochondria and regulates selective degradation of mitochondria. Mitophagy contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Recruits ATG11 to the surface of mitochondria. Promotes also autophagy-dependent peroxisome degradation (By similarity)."}]}
+{"id": "function_test_1188", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPAYRSRTTTHGRNMAGARGLWRATGMKDSDFGKPIIAVVNSFTQFVPGHVHLKDLGQLVAREIEAAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMAAMRLNIPAVFVSGGPMEAGKVVLKGKTHAVDLIDAMVAAADSAMSDEDVQTMERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSVLATHSDRKRLFVEAGHTIVDLARRYYEGDDASVLPRNIANFKAFENAMTLDIAMGGSTNTVLHLLAAAREAELDFSMKDIDRLSRRVPCLSKIAPSVSDVHMEDVHRAGGIMAILGELDRAGLLDTSCTTVHSETLGAALARWDIRQSNSESVRTFFRAAPGGVPSQTAFSQDRRYDELDLDREKGVIRDAAHAFSKDGGLAVLYGNIALDGCIVKTAGVDASILTFSGPVKVFESQDDAVSAILTNKIVAGDVVVIRYEGPRGGPGMQEMLYPTSYLKSKGLGKACALITDGRFSGGTSGLSIGHVSPEAAEGGLIGLVRDGDRISIDIPNRTISLDVSEAELAKRGEEERARGEAAWTPKDRKRNVSAALQAYAMLTTSAANGAVRDVKRRFGKN", "output": "Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively."}]}
+{"id": "function_test_1189", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MFTLKKSLLLLFFLGTINLSLCEEERDADEEERRDDPEERAVQVEKRILPILAPLIGGLLGK", "output": "Antimicrobial peptide. Has low activity against the Gram-positive bacterium S.aureus (MIC>100 uM) and the Gram-negative bacterium E.coli (MIC>100 uM). Has weak hemolytic activity against human erythrocytes."}]}
+{"id": "function_test_1190", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKLSRRSFMKANAVAAAAAAAGLSVPGVARAVVGQQEAIKWDKAPCRFCGTGCGVLVGTQQGRVVACQGDPDAPVNRGLNCIKGYFLPKIMYGKDRLTQPMLRMKDGSYHKDGEFTPVSWEQAFDVMEEKFKTSLKEKGPEAIGMFGSGQWTIWEGYAAAKLFKAGFRSNNIDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGSNMAEMHPILWSRITNRRLSDPNVKVAVLSTFQHRSFELADNGIVFTPQSDLVILNYIANYIIQNNAVNQDFFTKHVNLRKGATDIGYGLRPTHPLEKAAKNPGSDASEPMSFDEYKAFVAEYTLDKTAEMTGVPKDQLEQLAQLYADPNKRVISYWTMGFNQHTRGVWANNLVYNLHLLTGKISQPGCGPFSLTGQPSACGTAREVGTFSHRLPADMVVTNEKHRDICEKHWQIPAGTIPAKVGLHAVAQDRALKDGKLNVYWVMCNNNMQAGPNINEDRMPGWRDPRNFIIVSDPYPTVSALSADLILPTAMWVEKEGAYGNAERRTQFWRQQIKAPGEAKSDLWQLVQFSRRFKTEEVWPEALLAQKPELRGKTLYDVLFATPAVSKFPLSELKEDQLNDESRELGFYLQKGLFEEYAWFGRGHGHDLAPFDDYHNARGLRWPVVEGKETQWRYSEGNDPYVKAGEGYKFYGKPDGKAVIFALPFEPAAESPDNEYDLWLSTGRVLEHWHTGSMTRRVPELHRAFPEAVVFIHPLDAKARDLRRGDKVKVSSRRGEVISIVETRGRNRPPQGLVYMPFFDAAQLVNNLTLDATDPLSKETDFKKCAVKLAKV", "output": "Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite."}]}
+{"id": "function_test_1191", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIEADRLISAGATIAEDVADRAIRPKLLAEYVGQPQVRSQMEIFIQAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGIVQRLEFYQVPDLQHIVGRSARHMGLEMSDDGALEVARRARGTPRIANRLLRRVRDFAEVKHDGAISAEIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATVRAWNHFGITPPEMP", "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA."}]}
+{"id": "function_test_1192", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNKKNNLLVLEDGVKVILAPAKVNFGLWIKGKRPDGYHDIFSIIHTIDLYDRIYIELHYTLEVLSVGPFSKNLKDNIVYEGVLAFSRLTGKNFDYKIVIEKNIPVGAGLGGASSDLAAVISYLNEELENPMKEQELTDFLSSFSKDAPFFLKGGCALVYGTGDQVKVLEPISREITVVYPNIEASTSKVYGAFTKQTEEVLLLEDILRLLEENDIENIIENHLQETAIEIYKEIGELIRFLESVGYKPYMSGSGSSVYVFGKLSDKIKMALESRGWYVYECKTI", "output": "Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol."}]}
+{"id": "function_test_1193", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYADEGADELVFYDITASSDGRVVDKSWVARVAEVIDIPFCVAGGIRSIDDAAKILSFGADKISINSPALADPTLITRLADRFGVQCIVVGIDTWFDDATGKYHVNQYTGDENRTRVTQWETLDWVQEVQQRGAGEIVLNMMNQDGVRNGYDLTQLKKVRDVCRVPLIASGGAGTMEHFLEAFRDADVDGALAASVFHKQIINIGELKAYLAGQGVEIRIC", "output": "IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit."}]}
+{"id": "function_test_1194", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLDSKLLRTELDETAEKLARRGFKLDVETLRNLEEQRKSLQVKTEELQAQRNSRSKSIGQAKAKGDHEEADRIMADVANLGSELDEAKAALAELQQQIEDIALSVPNIPDDSVPLGKDENENVEVLRWGTPLAYDFEVKDHVDLGEMADGLDFASAVKISGSRFIVMKGQFARLHRALSQFMLDLHTEEHGYTEMYVPYLVNPDSLFGTGQLPKFGEDLFHTSPLTEQVSDVPLKKLSLIPTAEVPVTNMVRDTITDEADMPLKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVELVQITRPEDSMAALEELTGHAEKVLQLLELPYRKVVLCTGDMGFGSRKTYDLEVWVPAQETYREISSCSNMWDFQARRMQARFRRKGEKKPELVHTLNGSGLAVGRTMVAILENFQQADGKIAIPQVLRKYMNGVEFIG", "output": "Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)."}]}
+{"id": "function_test_1195", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAAAIMAAEQEAAKGGGGRNRGGVQRVEGKLRASVEKGDYYEAHQMYRTLFFRYMSQGKHAEARELMYSGALLFFSHNQQNSAADLSMLVLESLEKSDAKVAEDLLENLAKLFSLMDPNSPERVAFVSRALKWSSGGSGKLGHPKLHQLLAITLWKEQNYSESRYHFLHSTDGEGCANMLVEYSSSRGYRSEVDMFVAQAVLQFLCLKNKTSASVVFTTYTQKHPSIEKGPPFVQPLLNFIWFLLLAVDGGKLTVFTVLCEQYQPSLKRDPMYNEYLDRIGQLFFGVPPKQTSSYGGLLGNLLNSLMGTGEDDDTEEGQEDSSPIELD", "output": "As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Recruited to ribosomes, it interacts with the transmembrane region of newly synthesized tail-anchored proteins and together with SGTA and ASNA1 mediates their delivery to the endoplasmic reticulum. Client proteins that cannot be properly delivered to the endoplasmic reticulum are ubiquitinated and sorted to the proteasome. Similarly, the BAG6/BAT3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum. The BAG6/BAT3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD), a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome. It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome."}]}
+{"id": "function_test_1196", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MMNPLIIKLGGVLLDSEEALERLFTALVNYRESHQRPLVIVHGGGCVVDELMKGLNLPVKKKDGLRVTPADQIGIITGALAGTANKTLLAWAKKHHIASVGLFLGDGDSVNVTQLDEALGHVGLAQPGSPKLINMLLENGFLPVVSSIGVTDDGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTASKAEQLIDQGIITDGMIVKVNAALDAARALGRPVDIASWRHAEQLPALFNGTPIGTRILA", "output": "Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate."}]}
+{"id": "function_test_1197", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKSGFVSIIGRPSTGKSTLLNSICGHQISITSSTPQTTRNKIKGIFTDKRGQIIFIDTPGFHLSKKNFNIALMNNVYSAIIETELIIYVIDIQDQPGTEENEILTIIQRSKINFIVAINKIDIHKTKEKEIMTFLEEKKIQKNKIIKISAEKQINIETMKDKIYENLNEGPLYYPKEYYTDQKINLRISEIIRGVTIKKLKEELPYSIYTEIEILEDRENKFFIKANIIVAGESQKGIIVGKGGKGIKSIGEESRKIISKILEKKCNLFLQVKLRKNWNKNAKLIKNLIN", "output": "An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism."}]}
+{"id": "function_test_1198", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLAKRIIPCLDTIGRNVVKGTSFVNIRIVGDAKELARRYEREGADEIVLLDITASEEGRGTFVDVVTEVASELFVPLTVGGGIKNIEDVRKLLKAGADKVSINTAAVENPDIINQIASEFGSQCLVVAIDVKKRGKKSWEVYVKGGKVPTGIDFKDWIVEVEKRGAGEILLTSIDADGHLSGYDYELLECALNYSNLPLIASGGAGSLEDLYKALKIGVDAVLAASIFHFGTYTIPEVKKYLKEKGIWVRLD", "output": "IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit."}]}
+{"id": "function_test_1199", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSDQQQPPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALSQVANEPITVFCAGRTDAGVHGTGQVVHFETTAQRKDAAWTLGVNANLPGDIAVRWVKAVPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGENDFTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHNQPESWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRYDLPKPPMGPLFLAD", "output": "Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs."}]}
+{"id": "function_test_1200", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGAHNYAIYLDKARNLLFATVEIESEERWNAVASTEICQRWWKYMTDVMPANPDNSPVSSELQEVFYLP", "output": "Involved in the anomeric conversion of L-rhamnose."}]}
+{"id": "function_test_1201", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRSPSLARLQTRAVFGLTRSARFQPQTLLRQRCASTAAFRSAAVAPAYQSKLGQWDQRRNASAAASAVLEAAKVNPDGLSQTAIIDNLDPVEAARLDKCRNIGIAAHIDSGKTTCTERVLFYTGRIKAIHEVRGRDSVGAKMDSMDLEREKGITIQSAATFCDWVKKDKEGVEQKYHLNLIDTPGHIDFTIEVERALRVLDGAVMILCAVSGVQSQTITVDRQMRRYNVPRISFVNKMDRMGANPFKAVDQINNKLKMPAAAVQVPIGAEDEFEGVVDLIRMKALYNVGGSGEEIMEKDEIPEKVKAIAEERRTMLIETLADVDDEIAEIFLEELTPSEDQIRAAIRRATIGLKFTPVFMGSALANKSVQPMLDGVIDYLPNPAEVENLALDQKREEASVKLVPYNSLPFVGLAFKLEESNFGQLTYIRVYQGTLRKGANVFNARNSKKVKVPRIVRMHSNDMEEVSEIGAGEICAVFGIECASGDTFTDGTLGYSMSSMFVPEPVVSLSIKPKQSKDGANFSKAMARFQREDPTFRVSYDSESDQTIISGMGELHLDIYVERMRREYRVDCETGQPQVAYRETIGNRVEFDHLLKKQSGGPGEFARVMGYMEPTGALEENKFEQQVIGGSISEKFLYACEKGFNLSCEKGPLIGHKVLGTRMVINDGATHMTDSSEMSFKNATQQAFRKAFAESQPSVLEPLMKTVVTAPTEFQGDVIGLLNKRNATINDTETGVDEFTVHADCSLNGMFGFSSNLRAATQGKGEYTMEFSHYEKAPPHMQKELIAKYVKAQADRHKK", "output": "Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome."}]}
+{"id": "function_test_1202", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSKPIVMERGVKYRDADKMALIPVKNVATEREALLRKPEWMKIKLPADSTRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCDVAHGRPVAPDANEPVKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIREKSPQIKIETLVPDFRGRMDRALDILTATPPDVFNHNLENVPRIYRQVRPGADYNWSLKLLERFKEAHPEIPTKSGLMVGLGETNEEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQRYVSPDEFDEMKAEALAMGFTHAACGPFVRSSYHADLQAKGMEVK", "output": "Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives."}]}
+{"id": "function_test_1203", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVDQRPRAGSRSFTAPSLIGTNGHFASVGDAAHDPKAYEHGVQVIDEEKEFNPNLSKYLSLEDVTNAGFNYHLISVFGSQSTGKSTLLNHLFGTQFSVMSDKERRQTTKGIWMSKNKTKHEDPNARMADNILVMDVEGTDGRERGEDQDFERKSALFALATSEVLIVNIWEHQVGLYQGANMGLLKTVFEVNLQLFLKDKNTTHRSLLFFVIRDFMGNTPLKNLETTLLEDLSRIWASLSKPQGLERSTIHDYFDFAFYGLPHKGYKPDEFAAEAKKLGSRFREGRRDRKEQLMGASIENGVFLPEYHRRIPADGFAHYANGIWDQIVNNKDLDLPTQQELLAQFRCDEISREVIAAFDEAIAPFEEKQAAGVRAGELVILGGLGAAMRGARVKAVKNFETEASRYHKGVYQRKRAELEGKIDTRLKALFQGQLNAAHKSGVKDFSDAVSNAVKAGQKKGASYDFAEIVKQETKAALERYEKEARASLVEGTSWSNYKQELKLYQKDLAEVSGQLRRDEMRRLATRVERWVRSRLSDSVSLEFNSLGSGRGGSGAPETGEKPSESKIWDRIWNLFVETVLDAERRFTDRATSFDASVDEVDVGLWRLRRKSWGVLRLKVEEEMMEGNLLLKLRENFEDKFRYDEAGVPRIWRPTDDIEGIYTRARESTLTLIPLLSKFHLAENNAPPPLDRWVGHTPSSATAADEEDLTPIGGVDEEDGKSLEEEVTILNDAKRQDLTVRFKKAADGVYVEAKRSAIGGITQVPLYFYGLLLALGWNEIWAVLRNPAYFFLLFVCAIGAYVTYQLNLWGPILKMADAASRQALEELKKKLREFLEASDTGRQAMAMSSGEEYEMSSLNRGGKRVEDEDENDDI", "output": "Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization."}]}
+{"id": "function_test_1204", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MFRTMMRAKLHRATVTEANLNYVGSITIDEDLMDAVNIVENEKVQIVNNNNGARLETYVIKGERGSGVVCLNGAAARLVQPGDKVIIICYGLVTEEEVHKQEPKIAVLDDNNQIIEMLGAEKAGTIL", "output": "Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine."}]}
+{"id": "function_test_1205", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDNFLALTLTGKKPVITEREINGVRWRWLGDGVLELTPLTPPQGALVISAGIHGNETAPVEMLDALLGAISHGEIPLRWRLLVILGNPPALKKGKRYCHSDMNRMFGGRWQLFAESGETCRARELEQCLEDFYDLGKESVRWHLDLHTAIRGSLHPQFGVLPQRDIPWDEKFLTWLGAAGLEALVFHQEPGGTFTHFSARHFGALACTLELGKALPFGQNDLRQFAVTASAIAALLSGESVGIVRTPPLRYRVVSQITRHSPSFEMHMASDTLNFMPFEKGTLLAQDGEERFTVTHDVEYVLFPNPLVALGLRAGLMLEKIS", "output": "Transforms N(2)-succinylglutamate into succinate and glutamate."}]}
+{"id": "function_test_1206", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSDQQQPPVYKIALGIEYDGSRYYGWQRQNEVRSVQEKLEKALSQVANEPITVFCAGRTDAGVHGTGQVVHFETTAQRKDAAWTLGVNANLPGDIAVRWVKAVPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGENDFTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHNQPESWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRYDLPKPPMGPLFLAD", "output": "Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs."}]}
+{"id": "function_test_1207", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNPLIIKLGGVLLDSEEALERLFSALVNYRESHQRPLVIVHGGGCVVDELMKGLNLPVKKKNGLRVTPADQIDIITGALAGTANKTLLAWAKKHQIAAVGLFLGDGDSVKVTQLDEELGHVGLAQPGSPKLINSLLENGYLPVVSSIGVTDEGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAAKAEQLIEQGIITDGMIVKVNAALDAARTLGRPVDIASWRHAEQLPALFNGMPMGTRILA", "output": "Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate."}]}
+{"id": "function_test_1208", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKKNQFLKESDVTAESVFFMKRRQVLKALGISAAALSLPHAAHADLLSWFKGNDRPPAPAGKPLEFSKPAAWQNNLPLTPADKVSGYNNFYEFGLDKADPAANAGSLKTDPWTLKISGEVAKPLTLDHDDLTRRFPLEERIYRMRCVEAWSMVVPWIGFPLHKLLALAEPTSNAKYVAFETIYAPEQMPGQQDRFIGGGLKYPYVEGLRLDEAMHPLTLMTVGVYGKALPPQNGAPVRLIVPWKYGFKGIKSIVSIKLTSERPPTTWNLAAPDEYGFYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYADQVASLYRGLDLRENF", "output": "Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide."}]}
+{"id": "function_test_1209", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDYKETINLPRTEFPMRANLSKREPGIEKYWEENNVYEKAIKNREGNKQFILHDGPPYANGDIHIGHALNKILKDIVTRYKTLSGYYSPYVPGWDTHGLPIEHKVTKEMGDKAKDLSVSELRDKCRDYALKYVERQKEQFKRLGVWGEWDKPYLTLNPEYEVKQIEVFGEMAKRGLFYKGKKPVHWCPSCETALAEAEVEYGEHRSPSIYVKFPLKDKVNVGGVELTPGDSYVVIWTTTPWTIPANMAIALHPEFDYVVVKASGEKLVMARELVDRVMEEAEVENYKVVGQAFKGTELENKRCRHPFEDRDSILILGDHVTLEQGTGCVHTAPGHGHDDYLVGLKYDLDIYAPMDNRGVFTEEAERFAGMYYDDVNKEVTKILDEKGLLMNLSFISHQYPHCWRCKGALIFRATDQWFASIEAIKEEALKAIHSVDWYPAWGEERMANMISERTDWCISRQKKWGVPIPVFYCKDCGHSIINDETIEAVKKLFAREGSSGWYKYSAEEILPEGFSCPECGGKSFKKEEDIMDVWFDSGSSHKAVLETRDHLSWPSQLYLEGTDQYRGWFNSSLLTAVATEGKPPYEAVVTNGFVVDDKGNKMSKSIGNVVSPQDVIKRYGADILRLWVASSNFKDDVRVSDRILKQNSEVYRRIRNTFRFILGNINDFNPGQHYVDYNDRAEIDRWIMIKLQDLIKDVTRAYDEYEYHRVYHDVHNFCTIEMSSLYVDIVKDRLYTDGTNSLSRRSAQSTLYDILLVLVKLVAPVLAHTAEEVWQHLDESSKDAESIFLTDWPEVVNEYYDDRLMSKWDKLLEVRKDVAKALELSRENKEIGNSLDARVILVPVDDKQRQLLKDNIDILPDLFIVSQVELQGETGEGFHKGSETGISVSVVKASGEKCARCWKYSEAVGNDEEHPELCERCVEVVRTEV", "output": "Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)."}]}
+{"id": "function_test_1210", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKIKKKYCGHVIIVGKANVGKSTLLNNIIGKKISIVSRKKNTTQSNITGIKTEDNYQSIYIDTPGVVFDKNNNQMKHHKNNFYQTTQIATLIIFMIDRIDWTIHDEIILNEIKKTKIPILIIINKIDKISNKIILLPFINFLKKKIDFIEILPISAKKISNLILLKNIIKSYLPENCHIYPECYVTTNSDFFTVSEIIREQLILFLGDELPSIIKVEIESFKKKEKIALYIKAIIWVKNVRQKSIVIGHNGEKIKKISMISRNNIEKKFYIKTHLVLWVKDKN", "output": "An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism."}]}
+{"id": "function_test_1211", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIQKNWQELIKPNKVEFSSSGRTKATLVAEPLERGFGLTLGNALRRVLLSSLRGAAVTAVQIDGVLHEFSSIPGVREDVTDIVLNIKEIAIKMDGDDAKRMVVRKQGPGVVTAGDIQTVGDIEILNPHHVICTLDEGAEIRMEFTVNNGKGYVPADRNRAEDAPIGLIPVDSLYSPVKKVSYKVENTREGQVLDYDKLTMTIETDGSVSGEDAVAFAARILQDQLSVFVNFDEPQREAEEEAVTELAFNPALLKKVDELELSVRSANCLKNDNIVYIGDLIQKTEAEMLRTPNFGRKSLNEIKEVLASMGLHLGMEVPAWPPENIEDLAKRYEDQY", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_1212", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSWTIGRPDAEAPEDRMAASHLFTRLDDLVAWSRKHSLWPFNFGLSCCYVEMATALTPVYDQARFGAEVIRSTPRQADLLIVSGTVFRKMAVPLYRLYSQMREPRWVISMGACANSGGMYDIYSVVQGVDSFLPVDVYVPGCPPRPEALMEALVLLQSKIATEARPLQIRMGETGPARPFDPVPRRDALREARMAVTRLADPEAT", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_1213", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPVTIVLGGQWGDEGKGKITDALAATADIVVRPNGSTNAGHTVVTDEGVFKLHVIPSGILYPHCTCIIGAGVAVSPPDFLREIESLRERHPRLGQLYVSDRAHVIMPYHPLLDLYEERRRGAAGIGTTLRGNGPAFTDKIARRGIRIADLLPGSERSLRHKLETLLPEKNTLFIHLYGESPLDLDQLFEQARTWGEALAPYVIAAEVFVQDALDAGKSVIIEAAQGTMLDPDYGTYPYVTSSSPTAAGACQGAGVAPTQVDRIVGVFKAYTTRVGAGPFPTELTDETGQLIRERGREYGTTTGRPRRVGWFDAVAARYSARLNGMTEAALTKLDMLDPLPEVRICVGYRIDNQEVSAPPAQVERYAAVEPVYEVLPGWQCDTSQVTSFDDLPPEAQRYVARIEELIGVPITMIGVGPARRQILWRPAGALT", "output": "Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP."}]}
+{"id": "function_test_1214", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "VHWTAEEKALVNVVWSKTDHQAVVANALGRLFVVYPWTKRYFAGDSAVQTHAGKVVSALTLAYNHIDDVKPHKHYEGFHVDPENFRLLANCLNVELGHTLHKEFTPELHAAWNKFSNVVVDALSKGYH", "output": "Involved in oxygen transport from gills to the various peripheral tissues."}]}
+{"id": "function_test_1215", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "RLALPPGAVCNGHKSDCQCFGAKYKCSCPFFWRFRKSAECHCKKGWAWTAIKKRSCHNRYQWSD", "output": "Insecticidal to house crickets . It induces an excitatory slow-onset impact that leads to irreversible spastic paralysis . It also modifies human voltage-gated potassium channel Kv1.5/KCNA5 . Most likely, it binds to the voltage-sensing domain of the channel, suggesting it does not block the pore but prevents its opening at physiological membrane potentials . The recombinant peptide binds to the channel in an irreversible manner and slows down the hKv1.5 current activation kinetics . It is not toxic to mice, when intracranially injected (at 0.5 ug/g mouse) ."}]}
+{"id": "function_test_1216", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPQLQGLNHLLFSVSDLEKSFCFYRDVLHAKPLVRGRKLAYFDLNGYWLALNEEPDIPRNEIAHSYTHMAFTITEESFDEWYAHLEKHGVTILHGRDRSERDKRSIYFIDPDGHKFELHTGTLQDRLAYYRDEKHHMTFFE", "output": "Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor."}]}
+{"id": "function_test_1217", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKEPPSLLWGLDPVFLSHARLYIKDILELKESNQVPGIFFYKDHPIKQVDILGTVVCVREKDAFYSYGDVHRSTSGANDLDGLVQELHRQESSKAKMEIGDVIRVRGYIKVFRMQREVVASIFYKVDDPTLDMQIMRMLELPYLYKHAYDKPFILPEDMTNQSQEQPNQAVLQRSGLISLLSEKIMNFVKENTIYNFYLPELESMPSLLSEATNPHYITESDSNVSSSSREIRSLFKEAIHILLKRGIVYQKGQNKDVYYVTDHDKELHKLTLNMIKQDCSRQGHAEKGCHFLHILNCVQQDFGSCINEAILQRVINALEQNSDIVSTMEKYYTAF", "output": "Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication."}]}
+{"id": "function_test_1218", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNKKILETLEFDKIKALFEPHLLTEQGLEQLRQLAPTAKADKIKQAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLTSRELQSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHDSESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTVYIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRAKVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGKTIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNIVDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYGIETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQDNDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRVLKKLYNELNREKETELNKAREQAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAKKKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPVKKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTGVIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG", "output": "Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity."}]}
+{"id": "function_test_1219", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSEYLFTSESVSEGHPDKVADQISDAILDAILTQDKHARVAAETLVNTGLVVLAGEITTHANVDYIHVARETIKRIGYNTSDLGFDAKGCAVLVGYDKQSPDIAQGVNEGQGIDLNQGAGDQGLMFGYACDETPTLMPFPIYYAHRLVQRQAELRKDGRLPWLRPDAKSQITCAYDSETGLPKRIDTVVLSTQHSPDISHDMLTEAVIEDIVKPVLPAHMLTAETKFLINPTGRFVIGGPMGDCGLTGRKIIVDTYGGAAPHGGGAFSGKDPSKVDRSAAYAGRYVAKNIVAAGLARQCQIQVSYAIGIAEPTSISVDTFGTNAIPNEKIVELVKRHFDLRPKGIIQMLDLLRPIYTKTAAYGHFGREEPEFTWEATDKAAALRADAGL", "output": "Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme."}]}
+{"id": "function_test_1220", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEQLKRKIREHGSVLSEQVLKVDAFLNHQVDPQLMRQIGQEFARRFRDQEIDKVITLETSGIAPALMTALELDVPLVFARKHRSLTLTDDLLTARVYSFTKQVESTVAISASHLAAGERILIVDDFLANGQAALGLAAIVRQAGARLVGIGIVIEKSFQPGRRALEEQGYRVESLARIASLAGSQVSFVE", "output": "Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis."}]}
+{"id": "function_test_1221", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPDYRSKTSTHGRNMAGARALWRATGMKDDDFKKPIIAIANSFTQFVPGHVHLKDLGQLVAREIERAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSREIIADSVEYMVNAHCADAIVCISNCDKITPGMLMAALRLNIPVIFVSGGPMEAGKTKLASHGLDLVDAMVIAADSSASDEKVAEYERSACPTCGSCSGMFTANSMNCLVEALGLALPGNGSTLATHSDREQLFLQAGRTIVELCKRYYGENDESVLPRNIANFKAFENAMTLDIAMGGSTNTILHLLAAAQEAEIDFDLRDIDRLSRHVPQLCKVAPNIQKYHMEDVHRAGGIFSILGSLARGGLLHTDLPTVHSKSIAEGIAKWDITQTDDEAVHTFFKAGPAGIPTQTAFSQSTRWDTLDDDRENGCIRSVEHAYSQEGGLAVLYGNIALDGCVVKTAGVDESIHVFEGRAKIYESQDSSVRGILADEVKEGDIVIIRYEGPKGGPGMQEMLYPTSYLKSKGLGKACALLTDGRFSGGTSGLSIGHASPEAAAGGAIGLVQDGDKVLIDIPNRSINLLISDEELAARRVEQDKKGWKPVEKRPRKVTTALKAYALLATSADKGAVRNKAMLDGL", "output": "Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively."}]}
+{"id": "function_test_1222", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKFKDLRDFVQQLEQRGELKRIQMPISPVLEMTEICDRTLRNKGPALLFENPTGFDIPVLGNLFGTPERVAFGMGAESVSELREIGKLLAFLKEPEPPKGLKDAWSKLPIFRKIIAMAPKVVKDAVCQEVVIEGEDVDLAMLPVQTCWPGDVGPLITWGLTVTKGPNKDRQNLGIYRQQVIGRNKVIMRWLSHRGGALDFREWCEKHPGKPFPVSVALGADPATILGAVTPVPDSLSEYAFAGLLRGNRTELVKCRGNDLQVPATAEIILEGVIHPGEMADEGPYGDHTGYYNEVDSFPVFTVERITHRIKPIYHSTYTGRPPDEPAILGVALNEVFVPILQKQFPEITDFYLPPEGCSYRMAIVTMKKSYPGHAKRVMLGVWSFLRQFMYTKFVIVTDDDINARDWNDVIWAITTRMDPKRDTVMIDNTPIDYLDFASPVSGLGSKMGLDATHKWPGETTREWGRVIVKDEAVTARVDAIWKELGID", "output": "Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis."}]}
+{"id": "function_test_1223", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MVAVIIKGNEVAEKKRAQLKEEVVKLKEQGIVPGLAVILVGEDPASRSYVKGKEKGCEQVGIYSELIEFPETITEERLLAEIDRLNGDDRINGILVQLPLPKHIEEKAIIERISPEKDVDGFHPISVGRMMTGQDTFLPCTPHGIVELVKETNLDISGKHVVVIGRSNIVGKPVGQLFLNENATVTYCHSKTQNMKELTKLADILIVAVGRPKMVTADYIKEGAVVIDVGVNRLETGKLCGDVDFDNVLDVASYITPVPKGVGPMTITMLLHNTVESAKRAGVVCK", "output": "Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate."}]}
+{"id": "function_test_1224", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MARFFQPKKHSTLDTKHQPVTIERLDHQGSGLAFLHKKPLFVDGALPGEEVLIQLTENKSKYARGQLIKVLKPSAERVAPFCAHYAQCGGCDLQHLDRAGQIHHKQQALSQLMVKFAGQSLALSAPVCSDDQGYRRRARLSLMWDKKTQQLQLGFRRKQSKAIVNVTHCPVLEPSLNALLPDLNALLSEWSQPERLGHVELVKGDNTRVLVLRHLGALIEQDQQRLTDFASQNQLTLYLMLEAGELQHVQGEAPYCEETGSRLSFLPSHFIQVNRAVNQHMVVQALNWLEVSPQERVLDLFCGLGNFTLPLAKQAQAVVGVEGVDEMVQHATHNAKLNQINNVAFYQANLEQDMTSASWAQQKFAKVLLDPARAGAEGIVDQLSALGAKRVVYVSCNPATLARDSQSLLSQGFRLEKLGMLDMFPHTSHLESMALFVKKG", "output": "Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA."}]}
+{"id": "function_test_1225", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKIGIIAYQGSFEEHYLQLKRAFDKLSINGEITPVKIPKDLKDIDGVIIPGGESTTIGLVAKRLGILDELKEKITSGLPVMGTCAGAIMLAKEVSDAKVGKTSQPLIGAMNISIIRNYYGRQRESFEAIIDLSKIGKGKANVVFIRAPAITKLWGKAQSLAELNGVTVLAEENNILATTFHPELSDTTSIHEYFLHLVKG", "output": "Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS."}]}
+{"id": "function_test_1226", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNTMSHKFVLALDEGTTSARAILFDSDLNIVNIGQYEFPQHYPQPGYVEHDPEEIWEAQMLAVKKAISKIDAKQIVAIGITNQRETTVLWDAKSGKPVYNAIVWQDRRTSPITDWLKANYFKMIKDKTGLVPDPYFSASKIKWILDNVPNVREKAERGEIKFGTLDTYLIWRLTNGKAHVTDYSNASRTMLFNINKLECDREILELLKIPESILPEVKPSSEIYGYSEALGNLIPISGDAGDQQAALFGQVAFNVGEIKATYGTGSFILMNIGNNPIRSENLLTTIAWGLEKNKATYALEGSIFITGAAVQWFRDGLRAIDVSDEIEPLASNVEDNGGVYFVPAFVGLGAPYWDPYARGLIIGITRGTTKAHIARAILESMAYQTRDVIEVMQKESGISINSLKVDGGAAKDNLLMQFQADILGIKVIRPKVMETTSMGVAMLAGLGVGLWNSLEELRSIWKVDKEFIPSMSEEKRRALYSGWKEAVKRAMGWAKVVGGQV", "output": "Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate."}]}
+{"id": "function_test_1227", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDERLLSGESAYEDADLEYSLRPQTLRQYIGQDKAKHNLEVFIEAAKMREETLDHVLLYGPPGLGKTTLANIIANEMGVNVRTTSGPAIERPGDLAAVLTSLQPGDVLFIDEIHRLHRSIEEVLYPAMEDFCLDIVIGKGPSARSVRLDLPPFTLVGATTRAGALSAPLRDRFGVLSRLEYYTVDQLSAIVERTAEVFEVEIDSLAALEIARRARGTPRIANRLLRRVRDFAQVRGNGTVTMEITQMALELLQVDKLGLDHIDHKLLLGIIEKFHGGPVGLETVSATIGEESHTIEDVYEPYLLQIGFLQRTPRGRIVTPLAYEHFGMEMPKV", "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA."}]}
+{"id": "function_test_1228", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRYVLLGPPGAGKGTQAALLSEKLGVPHISTGDLFRANIGEGTPLGLEAKSYIDAGKLVPTDVTARMVEDRLNQDDAKDGFLLDGFPRTVQQADILEKLLSDKDLKLDGVLNFEVSEDVVVERMLARGRADDTEETIRTRLGVYREETFPLIEHYGDAIISIKAEGTVEEINERTLQAMGK", "output": "Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism."}]}
+{"id": "function_test_1229", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKNNFYQEDELLSNELSNRGFLLTKVDDVIGWARANSLWPMTFGLACCAVEMMQAAASRYDMDRFGMLFRPSPRQSDLMIVAGTLTNKMAPALRKVYDQMAEPKWVLSMGSCANGGGYYHFSYSVVRGCDRIVPVDVYVPGCPPTAEALIYGLMQLQKKIKRTTGFKYDARQTH", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_1230", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSTAKLVKSKATNLLYTRNDVSDSEKKATVELLNRQVIQFIDLSLITKQAHWNMRGANFIAVHEMLDGFRTALIDHLDTMAERAVQLGGVALGTTQVINSKTPLKSYPLDIHNVQDHLKELADRYAIVANDVRKAIGEAKDDDTADILTAASRDLDKFLWFIESNIE", "output": "During stationary phase, binds the chromosome non-specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Dps also protects the cell from UV and gamma irradiation, iron and copper toxicity, thermal stress and acid and base shocks. Also shows a weak catalase activity."}]}
+{"id": "function_test_1231", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYNATRAQAGNFIALCKNAELACEVTLQPLRRFPLDAAILFSDILTVPDAMGLGLYFETGEGPRFTHSVTCHADIQRLPIPDPEQELGYVMDAVRTIRRSLRGDVPLIGFSGSPWTLATYMVEGGSSKAFTKIKKVMFSDPAALHLLLDKLAQSVILYLNAQIRAGAQAVMIFDTWGGVLTGRDYREFSLRYMHQIVDGLQRESEGRRVPVTLFTKGGGQWLEAMADTGCDALGLDWTCDIADARRRVGGRVALQGNMDPSLLYAPPARIEQEVETILAGFGQGEGHICNLGHGIHPDVPPKHAGVFVDAVHRLSVPYHR", "output": "Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III."}]}
+{"id": "function_test_1232", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSQLLTPRQAEELHKSIIAYFLSAKLPKSAAALREEIADSVQLDDSTAKKYEGLLEKKWTSVVRLQKKIMDLEARNSALQSELDSATPTSLSRRNQDPVSWLPRAPARHRLESHRNPVTSVAFHPVFSSLASGSEDTTIKIWDWELGELERTIKGHTRAVVDVDYGGPHGGTLLASCSSDLTIKLWDPSDEYKNIRTLPGHDHSVSAVRFIPSGAAGSPLSGNLLVSASRDKTLRIWDVTTGYCVRTLHGHVEWVRDVVPSPDGRFLFSAGDDRVARLWDVSSGETKSTFLGHEHFIECVALAPPTTYPYLAALAGLKKPPPPSSSAEYVATGSRDKTIRVWDSRGTLIKTLIGHDNWVRALVFHPGGKYLLSVSDDKTIRCWDLSQEFKCVRVVTDAHAFVTCIRWAPNIIKDAGGMGVNGDINGGGSLALSGVNGIIPGSKKEDPGGGAKLGIRCVIATGSVDLNVRVFAS", "output": "Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs."}]}
+{"id": "function_test_1233", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDHFKQLEVWFVIGSQHLYGPETLRQVKENAEKVVTGLNQQANLPVKLVLKPLVKTPDEILALCRDANYQDNCIGLLTWLHTFSPAKMWIGGLSILSKPLLQFHTQFNAEVPWDTMDMDFMNLNQTAHGGREFGFIGARMRQAHQVVVGHWQDKNAHARIGKWMRVAAAIQESKQLKVARFGDNMREVAVTEGDKVGAQIQFGYSVSAWGLGDLTAVVDAVSKGDINALVDEYEASYQLTDAVKLNGANRQNLLDAAQIELGMKRFLEQGGYHAFTTDFENLYGLKQLPGLAVQRLMQQGYGFGGEGDWKTAALLRIMKVMASGLSGGTSFMEDYTYNFQNGNDLVVGSHMLEVCPTIAKEQKPILDAQYLGIGGKADPARLIFSTPAGPSLNASVIDMGDRFRMLVNLVDTIEQPHPLPKLPVARAIWKAQPSLDVAAEAWILAGGAHHTVFSQALDLEHMRLYAEMQNIELLVIDNETRLHEFKDALRWNEVYYKLCSR", "output": "Catalyzes the conversion of L-arabinose to L-ribulose."}]}
+{"id": "function_test_1234", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MATGKIIQVIGAVVDVEFPQDAVPKVYDALEVENGAEKLVLEVQQQLGGGIVRCIAMGSSDGLRRGLNVNNLDHPIEVPVGKATLGRIMNVLGEPIDMKGDIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDVARGVQSILQRYQELKDIIAILGMDELSEEDKLVVSRARKIQRFLSQPFFVAEVFTGSPGKYVALKDTIRGFKGIMEGEYDHLPEQAFYMVGSIDEVVEKAKKL", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits."}]}
+{"id": "function_test_1235", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSQITDVYAREILDSRGNPTLEVEVFLDSGVMGRAAVPSGASTGEREALELRDGDKGRYLGKGVEQAVSNVNDIIADEITGMDATDQVGIDKKMLELDGTEFKSRLGANAILGVSLAVAKAAAEEVGVPLYQYIGGCNAKELPLPMMNIINGGAHADNNVDIQEFMIMPAGAANFKEALRMGAEIFHALKSVLKGKGYNTAVGDEGGFAPNLKSNEEALEVIMEAIVKAGYKPGEEVLLALDVASSELFENGVYTLENEAESKKTADQLVDFYENLVNKYPIVSIEDGMAENDWDGWKKLTDRLGKRIQIVGDDLFVTNPSILKEGIKKGIANSILIKLNQIGTLTETLDAIEMAKRAGYTCVISHRSGETEDTTLADLAVAVNAGQIKTGSLCRTDRVCKYNQLLRIEDELDDVAQFRGHEVFYNIKK", "output": "Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis."}]}
+{"id": "function_test_1236", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPKFFCDYCDVYLTHDSMSVRKAHNSGRNHLRNVVDYYQQIGHEKAQSVIDSITSSYAAEGQAHANPMLPQNQPGQGFPPPPFGFPGGIPPPFPGMPGAPPGQFPQGMPPPPGGGRGMPPMPPFPPGPNGMPVPPNGLPFPPPGGFPFPPPGAPGAPGAPGASGGAPPPFPGLPGMPPPGQGFPPGGPPGFAPPGAGAPGHEKR", "output": "Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region."}]}
+{"id": "function_test_1237", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLCKTGGCVEGRAAEDQSTRKVHWGQEGSGQSPEARPRALDMISRLEPSRGPSHAHWWHIISPQLAVMLEETGYPVEKQLEILTFLYHWVIPYLAPVAAGNAASSCNWKSLLPSAIVPLEYSWKWDSSGKAREPEIRLTIEVFGELSGTQFDPLNQAPAMELLYRLSSILPGVNQILASHFRCKFFDHDNVKYMEEPRLDTLPRSTMLTYMTPRKLGQQGFAPLSEYVSAIQALGQASGRTLDTLTNFLSTSPEGVHLHPFGLAFDNVEPSSSRLKLYFFSNRTSYNSMREVLTLGGRIYSESYDMEEKLRTIYSLAQLLMGCPENNAEDADIPLLPITHSQHTAAERATLLSGFQYYFDVAPGADLPSVKFYIPVRKEHANDRAVGSALTGWFREQGRGKFCDNYMRMLERLAGGLELGECRGLHSFISCMIGGDGEIEVTSYLLPGSEA", "output": "Prenyltransferase; part of the gene cluster that mediates the biosynthesis of the aspoquinolone mycotoxins . Within the pathway, the prenyltransferase asqH1 catalyzes the canonical Friedel-Crafts alkylation of quinolinone B with dimethylallyl cation to yield dimethylallyl quinolone (By similarity). The first step of the pathway is catalyzed by the nonribosomal pepdide synthetase asqK that condenses anthranilic acid and O-methyl-L-tyrosine to produce 4'-methoxycyclopeptin. 4'-methoxycyclopeptin is then converted to 4'-methoxydehydrocyclopeptin by the ketoglutarate-dependent dioxygenase asqJ. AsqJ also converts its first product 4'-methoxydehydrocyclopeptin to 4'-methoxycyclopenin. The following conversion of 4'-methoxycyclopenin into 4'-methoxyviridicatin is catalyzed by the cyclopenase asqI. 4'-methoxyviridicatin is the precursor of quinolone natural products, and is further converted to quinolinone B. The prenyltransferase asqH1 then catalyzes the canonical Friedel-Crafts alkylation of quinolinone B with dimethylallyl cation to yield dimethylallyl quinolone, which is subjected to FAD-dependent dehydrogenation by the FAD-linked oxidoreductase asqF to yield conjugated aryl diene. The delta(3') double bond then serves as the site of the second alkylation with DMAPP catalyzed by the prenyltransferase asqH2 to yield a carbenium ion intermediate, which can be attacked by H(2)O to yield a styrenyl quinolone containing a C3'-hydroxyprenyl chain. The FAD-dependent monooxygenase asqG performs epoxidation of the terminal C7'-C8' olefin. Finally, after dehydratation of the epoxide at C3 by asqC, the quinolone epoxide rearrangement protein asqO catalyzes an enzymatic 3-exo-tet cyclization to yield the cyclopropyl-THF ring system in aspoquinolone (Probable)."}]}
+{"id": "function_test_1238", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRKHSDCMNFCAVDATKGICRLSKQMINLDDSACPEIKVMPKCKNCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE", "output": "Component of the HPA decarboxylase that decarboxylates phenylacetates with a hydroxyl group in the p-position. Active toward 4-hydroxyphenylacetate and 3,4-dihydroxyphenylacetate, forming 4-methylphenol and 4-methylcatechol, respectively. Is likely involved in the catabolism of aromatic amino acids such as tyrosine fermentation. 4-methylphenol (p-cresol) formation provides metabolic toxicity, which allows an active suppression of other microbes and may provide growth advantages for the producers in highly competitive environments (By similarity). The small subunit is essential for enzymatic activity of HPA decarboxylase, and seems also involved in the regulation of the enzyme oligomeric state and catalytic activity (By similarity)."}]}
+{"id": "function_test_1239", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MVTLPLLLSILPLAAVFSSAASLQVRENHDCASIQPPQVPGAEILSVIGVQRRVEVAPFPPSPSKPNTTIDICSVNVTLSHMGVNDKVVVSVWLPLPDKWNGRFQATGGGGWAAGTFDLLMGPAALEGYSTAGTDAGVTVDPGSADKWALKEDGTVNYDLLENFASRSIHDMAIVGKAVTESYYKKPANYSYFYGCSNGGRQGMVEAQKYPDDFDGILAGAPAIYWPQFLTSTEWPQVVMQSEKVFPSQCVFEAFRKAGIAACDKLDGVEDGVVSNLDGCEFNPFALVGKKVKCGEESTTITLAQAWVAKKIYDGPKSTAKHALWDVLPVGASYVGLANSTIENGVPKIAPFVIGSSWIRSFLKKDVNFDLSTITYADMPKLFQQSIDEFDKIAGGSNPDLSALKKSGTKLLSWHGLADELIHPQGSIKYRQAVEHRMGGGSEVDNYYRLFLAPGVTHCGIGVNDGAAPIDTLKVLVRWVEKGEAPETMPATATDASGTTTLFTRNLCRYPLVPRYKGGDKNSADSFECAKDFGSHH", "output": "Hydrolyzes the feruloyl-arabinose ester bond in arabinoxylans as well as the feruloyl-galactose and feruloyl-arabinose ester bonds."}]}
+{"id": "function_test_1240", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MELAKTKTGEMIDLNFARKVVEENKRVKDNRGRQEIVLFNGLTTSKLRNLLELINHVYTKVYNSDDTTLSEDVRDELEYLKVKFAYESGREPAVRTFIEKTYVDKLVDVVLKKNTKKIFLDYCKYFEALVAYAKFYRMGD", "output": "CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). The type III-A Csm effector complex binds crRNA and acts as a crRNA-guided RNase, DNase and cyclic oligoadenylate synthase; binding of target RNA cognate to the crRNA is required for all activities. In a heterologous host the appropriately targeted Csm effector complex prevents growth of dsDNA phage phiNM1-gamma6.; "}]}
+{"id": "function_test_1241", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "PIAGSMVLAAILLKLGGYGIIRMMQIMPTTKTDTFLPFLVLALWGAILANLTCLQQTDLKSLIAYSSISHMGLVVAAIIIQTPWGLSGAMALMIAHGFTSSALFCLANTTYERTHTRILILTRGFHNILPMATTWWLLTNLMNIATPPTMNFTSELLIMSTLFNWCPTTIILLGLSMLITASYSLHMFLSTQTGYPLLNNQTEPTHTREHLLMILHIVPLMMISMKPELVI", "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)."}]}
+{"id": "function_test_1242", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEDYNNQMDHESSGGRGNFLYASPNLGGNYGRAASDHQMGINTFHLQSSGGGGGGGSGDQCNFQSPGTHPINVKTEATTSQHGHPKFQYNNNNNNHHLVSSSRGHQPVVHQLQHNLDLQNDDHSLSSNEVEAIKAKIIAHPQYSNLVEAYMDCQRVGAPSDVVPRLSVARQEFEARQRSSGTSRETSKDPELDQFMEAYYDMLVKYREELTRPIQEAMDFMRRIETQLNMLGNNNNAPPLRIFSPSEDKCEGIGSSEDEQENSGGETEVPEIDPRAEDRELKNHLLRKYSGYLSSLKQELSKKKKKGKLPKEARQKLLSWWELHYKWPYPSESEKVALAESTGLDQKQINNWFINQRKRHWKPSEDMQFMVMDGLHPQNAALYMDGHYTGDVHYRLGP", "output": "Probably binds to the DNA sequence 5'-TGAC-3'."}]}
+{"id": "function_test_1243", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKCGLEIHVQLDTRSKLFCRCPTDYQEAPPNTNICPVCLNQPGAKPYPPNRSALEGALKIALMLDCRINPEITYFMRKHYNYPDLPSGYQRTSIPVGLEGELNGVRIREVHIEEDPGQYKPDQGTVDFNRSGIPLIEIVTEPDMTSPEEARNFLRELIRVLEYSGCARGEGTMRADVNISLEGGKRVEIKNINSIKGAYKALKFEMIRQKNLLKRGVEVKQETRAFLESQMITVSMRLKEEAEDYRYIPDPDLPPMKFTDEVVEGLRERIPEAPHLKVKRFMEEYGLREEDARVLTSELELADAFEEVAGSIDPEFAALWMRDELKRVLYYNKISFAESMITPGDIIELLAMIRKKEITSKAAKKIIEEMPLNKKGPREIATEMGLIGIIDESEVIRAVEQAIRENPGAVEDYHAGKEAAINFLVGQVMRMTRGKAEPERTVELIKERI", "output": "Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)."}]}
+{"id": "function_test_1244", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRFKTVDLPYHVYIGENVISKLPKVLRSLDANYFLLLTDEVVKNLVVVNLKETLKDFEYDMMLVESAKMEEARKIVLRGGFADYDAVVGVGGGKVLDVSKVVSSELNASMISVPTTASHDGIASPVASFKENGKPISISTNPPSAVIADLNIIKNCPIRLLRSGYGDLVSNISSVKDWQLARDLVGEDYNEVAASIAVMPAQLMVSKADELDLTLPPHLLMLLRGLIMSGVAIAFVGSSRPASGAEHKFSHALDYLGYGNGTHGEQVALGTIIMEYLHEKYYGRGDWEQIKMSLEKVHAPTTAKEIGLTREQVIEALMLATKLRKKRFTILEAVKPTKEEFELVVEKTGVA", "output": "Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea."}]}
+{"id": "function_test_1245", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MENPDSAFLLFRNAPRLPLATMHTPLCGDSHQPDFAFRKPARDALLRPWNGRNHRCGLQDGREICQGQLPAHQKSYWSDCAALPRLFRAYGGAVVRGFLIVGNKAFTQPFSLNDLPGAGRMDVLCRCTSQALFISHGIRRDVEVYLLLLGPPSPPKSILIKGDEVRRMSPDERNVAGHIKKALAVECGKSWKKVHSGVYVSRKGLEELIEELSEKYSIIYLKEDGVDISNAQLPPNPLFVIGDHEGLTEEQEKVVERYAALKLSLSPLSLLAEQCVVIAHHHLDRLQF", "output": "Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs."}]}
+{"id": "function_test_1246", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRVLVVDDSALVRMAVTDILTKAGIEVVDTAKNGREAVEKALKLKPDVITLDINMPEMDGLTALKLIMEKQPTPVVMLSSLTKEGARETLEALKIGAVDFVTKPDGALVDLSSVAQELVRKVQMAASTSLNVLRLQNLKKIKGEVVRGNWKGKTKDVCVLIGSSTGGPSALEMIIPRLPADIPAPVFVVQHMPPGFTKQLAERLNSISEVEVKEAENNERVKDGVVYVAPGGYHMKVRRAANVVRIKVVDGEPVNAVKPSVDVTADSVVQAYGGNVVGAILTGMGEDGAYGMKLIKDRGGLTIASSEDTCMVFGMPKAAIELGGITSVKPVFEIAEEIVRFLEVKLNER", "output": "Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid."}]}
+{"id": "function_test_1247", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MALESLKEVARKIAGSSSIDKKFVEEMVKEIQRALIKADVNVRQVKEISDAIKKRALSEDVLPALNAKEQILKIVYEELLRGVGEGLEIPLKKAKIMLVGLQGSGKTTTTAKMAKYFKDRGMKVAVVAADTWRPAAYEQLRQLAEEYGITFYGEKGEKDAVKIVKNALEKLKDHDMIIIDTAGRHALEDELIDEMIKIAEVARPDYKLLVLDAAIGQLASKQAQAFHEAIGINGIIITKFDGTAKGGGALSAARQIGIPIAFIGTGEKVEDFERFDPAGFVSRLLGMGDIKALMEKIERIASEEELDPEAFLKGTFTLKDIYKQIEAMNKMGPVRKIFEMLPFGLGLKVDNDVMEMTQEKMKKFRVIMDSMTEEELLNPKIIDSSRIRRIAIGSGTSPQEVKELLNYYKTMKNLMKKMKKNKLPIKGLGKLGF", "output": "Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY (Probable)."}]}
+{"id": "function_test_1248", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPQLNPEPWLTTFLIVWISLIVILQPKIASLMLTSSPTPYKAMTIKTWPWPWT", "output": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane (By similarity)."}]}
+{"id": "function_test_1249", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNKILEKIQNNTTILIEASAGTGKTHILENVVINLIKTKLYSINEILVLTFTKKATEEMHTRILKVIENAYSNSKTNEILKEAYEQSKKLFISTINKFALHALNNFQIETENYSKYKPKEKFSKEIDEIVYDFLRKSDSLIQALDIKDYELKVFKSDAKKTEEIVLKIKKAYERDTTQELGDWLKTQTAFENILLKKEELIKDYNKIIEDLDKMTKDEILSFYNKHIQTGKLEIEYSKENDIFKIAETLLKNKFFSTLIEKETKKNSKLSPKELKIKNDLICLGINIKHEKYKSEDNRNKNRNNLKQYVILKVEYKILKYIEKELKKTIKSTNTIDQNYIISNLKNYLKSEDKKLLNAIKNRYKIILIDEAQDLSLIQIEIFKILKTAGIKLIFIADPKQIIYSFRKADISFYNKEIKNKINTDARIVLKINHRSSKKLIGPLNKIFNNIYNNAIADEIEKIDFTNSLPNQKNDNNKIVINGQEIEGINIITTNTESEEDIYQKTALTIKYLLAYGKIAENNKIRNIKMQDIKVLCRGKNEINLIDKALKKEQIQTNKTQEKFLKTKEFSEIFYIIKCLDRKQSFKTLNYILSSKILNVPWNLQRILIKQDKICLIEEFIENIIVLLEKNEITLINAINKITFEKNLWIKIANITKDQKIIEWAKNKINYKGLLIKEGKLENLKTYETTLEIISKIYHKEQNIQSLISTLESLIINEEPEEIEEKINNINNDNESIELMTIHKSKGLGMNIVFLLNTTPIENSNFFSKKNQFYKFYQDGKIEYDFFKLEENKKYARLKILSEEKNIFYVGATRAKFALFIIKINSITSKLLEIAKIFTIDDIKHDFNIHEFIGQKRFNKKKYNTNVNTKLIPPKPIIKNMFKKEYTSSFSSLTAQAHHKEFYENYDFKNINYEKETELDYEPGLEETLPKGKDIGNILHAAMEEIIFSTAKDTFDNFKKNNIEIIEKQIQKINSNLNTIEIQNSLAKMIYNILTYNIRAINTRLCDIEELQKEMEFLIKINPEFQKQKYLFDKHFEDLHIKLSDGYLKGIVDLIFKANNKIYILDYKTNYLGKNKEDYNITNLENTIKKEYYDLQYKIYALGIKKILFKNKKEYNQKFGGIIYLFTRAFEDNIECLKSKFENGIYFNLPKFNDVDLDKIILELGIKRHL", "output": "A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA."}]}
+{"id": "function_test_1250", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MCGIVGYVGRDLALPIVLGALERLEYRGYDSAGVALIEDGKLIVEKKKGKIRELVKALWGKDYKAKTGIGHTRWATHGKPTDENAHPHTDEKGEFAVVHNGIIENYLELKEELKKEGVKFRSETDTEVIAHLIAKNYRGDLLEAVLKTVKKLKGAFAFAVITVHEPNRLIGVKQGSPLIVGLGEGENFLASDIPAILPYTKKIIVLDDGEIADLTPDTVNIYNFEGEPVSKEVMITPWDLVSAEKGGFKHFMLKEIYEQPKAINDTLKGFLSTEDAIPFKLKDFRRVLIIACGTSYHAGFVGKYWIERFAGVPTEVIYASEFRYADVPVSDKDIVIGISQSGETADTKFALQSAKEKGAFTVGLVNVVGSAIDRESDFSLHTHAGPEIGVAATKTFTAQLTALYALSVRESEERENLIRLLEKVPSLVEQTLNTAEEVEKVAEKYMKKKNMLYLGRYLNYPIALEGALKLKEISYIHAEGYPAGEMKHGPIALIDENMPVVVIAPKDRVYEKILSNVEEVLARKGRVISVGFKGDETLKSKSESVMEIPKAEEPITPFLTVIPLQLFAYFIASKLGLDVDQPRNLAKTVTVE", "output": "Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source."}]}
+{"id": "function_test_1251", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "METCDSPTISRQENGQSTSKLCGTTQLDNEVPEKVAGMEPDRENSSTDDNLRTDERKSEILLGFSVENAAATQVTSAKEIPCNECATSFPSLQKYMEHHCPNARLPVLKDDNESEISELEDSDVENLTGEIVYQPDGSAYIIEDSKESGQNAQTGANSKLFSTAMFLDSLTSAGEKNEQSASAPMSFYPQIINTFHIASSLGKPFTADQAFPNTSALAGVGPVLHSFRVYDLRHKRDKDYLTSDGSAKNSCVSKDVPNNVDLSKFDGCVSDGKRKPVLMCFLCKLSFGYIRSFVTHAVHDHRMTLNEEEQKLLSNKYVSAIIQGIGKDKEPLISFLEPKKSTSVYPHFSTTNLIGPDPTFRGLWSAFHVENGDSLQAGFAFLKGSASTAGSAEQPVGITQMPKAEVNLGGLSSLVANAPITSVSLSHSSSESNKLSESKDQENNCERQKETNTLHPNGEFPIKSEPTEPVEEEDEDTYSNELDDDEVLGELADSIGSKDFPLLNQSISPLSSSVLKFIEKGTSSSSATVSDDTDKTKQTAAHRHNSNVTSNYSISGKDFADASASKDSPTALHPNETARGDEDSSVTPHQHSFTPSTPSAGDGSPGSGIECPKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGSCVYCKTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQNLQNGNGEQVYGHTAPPSNPALSGCGTPSPSKPKQKPTWRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMKQIQHNLHLGLAPAEAELYQYYLAQNIGLTGMKLENPADPQMMINPFQLDPATAAALAPGLGELSPYISDPALKLFQCAVCNKFTSDSLEALSVHVSSERLLPEEEWRAVIGDIYQCKLCNYNTQLKANFQLHCKTDKHMQKYQLVAHIKEGGKTNEWRLKCIAIGNPVHLKCNACDYYTNSVDKLRLHTTNHRHEAALKLYKHLQKHESTVNPDSCYYYCALCDYSTKVKLNLVQHVRSVKHQQTEGLRKLQLHQQGLAPEEDNLSEIFFVKDCPPNELEVAQLGCRTCDISLTEQGEDTEGSAKSTSVAIGDDKDSSERDNTEAKKSSKDSVNTVVGAQQLLLAKEEDGAAKKSKPPEDNKFCHEQFYQCPYCNYNSRDPNRIQMHVLSQHSMQPVICCPLCQDVLSNKMHLQLHLTHLHSVSPDCVEKLLMTVPVPDVMMPNSMLLPAAASEKSERDTPATITAEGSGKYSGESPVDEKSTPGTDESKPGMEIKSEEQKPPKESAETPDWNKSGSKDIKTTDSMPDQLNEQQKKQQLSVSDRHVYKYRCNHCSLAFKTMQKLQIHSQYHAIRAATMCSLCQRSFRTFQALKKHLEAGHPELNEAELQQLCASLPVNGELWAEGESMGQDDHALEQEIERDYEMEQEGKASPVGSDSSSIPDDMGSEPKRTLPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKKVLQEASSPVPQETNSNTDNKPYKCSICNVAYSQSSTLEIHMRSVLHQTKARAAKLEPSGNISSGNSVAGNVNSPSQGILDSMSLPAVNSKEPHLDAKELNKKQASELISAQPTHHPPQSPAQLQMQLQHELQQQAAFFQPQFLNPAFLPHFPMTPEALLQFQQPQFLFPFYIPGTEFSLSPDLGLPGSATFGMPGMAGMTGSLLEDLKQQIQTQHHVGQTQLQILQQQAQQYQSTQPQLQSQKQQQQSSKLMKAEQTSLVSTDCQLIKDMPSYKESEEISEKQEKPKQEFTNESEGLKENKDMKKPKSSEPAIPPPRIASGARGNAAKALLENFGFELVIQYNENRQKVQKKGKTGEGENTDKLECGTCSKLFSNILILKSHQEHVHGQFFPYGALEKFARQYREAYDKLYPISPSSPETPPPPPPPPPPPPPPPPPTPSQPSSAGAGKIQNTTPTPLQAPPPTPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPPIMMQPVQHPALPPQLALQLPPMDTLSADLTQLCQQQLGLDPNFLRHSQFKRPRTRITDDQLKILRAYFDINNSPSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQRNKDSPYNFSNPPITVLEDIRIDPQPSAVEPYKSDASFSKRSSRTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRVIVVWFQNARQKARKSYENQAETKDNEKRELTNERYIRTSNMQYQCKKCSVVFPRIFDLITHQKKQCYKDEDDDAQDESQTEDSMDASDQTVYKNCTVSGQNDASKSLAVTAASSGSGSSTPLIPSPKPEPEKASPKSESTEKPKPNETISKQTDTTSQSSKPVQSASVTPSDPQPSASQPQQQKQSQIIGRPPSTSQTTPVPSSPLPISMTPLQNSLPPQLLQYQCDQCTVAFPTLELWQEHQHMHFLAAQNQFIHSQFLERPMDMPYMIFDPNNPLMTGQLLNSSLA", "output": "May play a role in neural and muscle differentiation (By similarity). May be involved in transcriptional regulation."}]}
+{"id": "function_test_1252", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSMMNRNIGFLSRTLKTSVPKRAGLLSFRAYSNEAKVNWLEEVQAEEEHAKRSSEFWKKVTYYIGGPALILASANAYYIYCKHQEHAKHVEDTDPGYSFENLRFKKYPWGDGSKTLFWNDKVNHLKKDDE", "output": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules unsing 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix."}]}
+{"id": "function_test_1253", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "AGEVEKREGMMKQIGGSMGALAAISKGQKPYDAEAVKAAVTTISTNAKAFPDQFPPGSETGSAAAPAIWENFDDFKSKAAKLGADADKVLASLPADQAGVTAAMQTLGADCGACHQTYRLKK", "output": "Low-spin monoheme cytochrome c."}]}
+{"id": "function_test_1254", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "SDEAVKYYTLEEIQKHNHSKSTWLILHHKVYDLTKFLEEHPGGEEVLREQAGGDATEDFEDVGHSTDARELSKTYIIGELHPDDRPK", "output": "Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases."}]}
+{"id": "function_test_1255", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKNFKLNRVKYKNIMSVGQNGIDIQLDKVQKTLITGRNGGGKSTMLEAITFGLFGKPFRDVKKGQLINSTNKKELLVELWMEYDEKKYYIKRGQKPNVFEITVNGTRLNESASSKDFQAEFEQLIGMSYASFKQIVVLGTAGYTPFMGLSTPARRKLVEDLLEVGTLAEMDKLNKALIRELNSQNQVLDVKKDSIIQQIKIYNDNVERQKKLTGDNLTRLQNMYDDLAKEARTLKSEIEEANERLVNIVLDEDPTDAFNKIGQEAFLIKSKIDSYNKVINMYHEGGLCPTCLSQLSSGDKVVSKIKDKVSECTHSFEQLSTHRDNLKVLVDEYRDNIKTQQSLANDIRNKKQSLIAAVDKAKKVKAAIEKASSEFIDHADEIALLQEELDKIVKTKTNLVMEKYHRGILTDMLKDSGIKGAIIKKYIPLFNKQINHYLKIMEADYVFTLDEEFNETIKSRGREDFSYASFSEGEKARIDIALLFTWRDIASIVSGVSISTLILDEVFDGSFDAEGIKGVANIINSMKNTNVFIISHKDHDPQEYGQHLQMKKVGRFTVMV", "output": "Exonuclease that plays a role in viral genome replication, DNA recombination, and host DNA degradation."}]}
+{"id": "function_test_1256", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPIDRKTLCHLLSVLPLALLGSHVARASTPGIVIPPQEQITQHGGPYGRCANKTRALTVAELRGSGDLQEYLRHVTRGWSIFALYDGTYLGGEYGGVIKDGTPGGAFDLKTTFCIMTTRNTGQPATDHYYSNVTATRLLSSTNSRLCAVFVRSGQPVIGACTSPYDGKYWSMYSRLRKMLYLIYVAGISVRVHVSKEEQYYDYEDATFETYALTGISICNPGSSLC", "output": "PTX oligomer B binds to receptors on the eukaryotic cell surface and facilitates the translocation of the toxic subunit across the cell membrane."}]}
+{"id": "function_test_1257", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGASGSKKRSKPLQGLQERLLQARGETCGGRCNESGGGYLQSHEGSGREQNSPSCEGQRYQQGDFVNTPWRTPAAEREKELYKQQNMDDVDLDDDDQVGFPVTPRVPLRPMTFKLAVDMSHFIKEKGGLEGLFYSQRRHRILDLYLDKAFTLYPEEFGHNSGLPEKEWKARLKARGIPFS", "output": "Factor of infectivity and pathogenicity, required for optimal virus replication. Alters numerous pathways of T-lymphocyte function and down-regulates immunity surface molecules in order to evade host defense and increase viral infectivity. Alters the functionality of other immunity cells, like dendritic cells, monocytes/macrophages and NK cells. One of the earliest and most abundantly expressed viral proteins (By similarity).; "}]}
+{"id": "function_test_1258", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEQAPEDQGPQREPYNEWTLELLEELKREAVRHFPRPWLHSLGQYIYETYGDTWAGVEAIIRILQQLLFIHFRIGCQHSRIGIIQQRRARRNGASRS", "output": "During virus replication, may deplete host UNG protein, and incude G2-M cell cycle arrest. Acts by targeting specific host proteins for degradation by the 26S proteasome, through association with the cellular CUL4A-DDB1 E3 ligase complex by direct interaction with host VPRPB/DCAF-1. Cell cycle arrest reportedly occurs within hours of infection and is not blocked by antiviral agents, suggesting that it is initiated by the VPR carried into the virion. Additionally, VPR induces apoptosis in a cell cycle dependent manner suggesting that these two effects are mechanistically linked. Detected in the serum and cerebrospinal fluid of AIDS patient, VPR may also induce cell death to bystander cells.; "}]}
+{"id": "function_test_1259", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSAREPAGRRRRASTRPRASPVADEPAGDGVGFMGYLRAVFRGDDDSELEALEEMAGDEPPVRRRREGPRARRRRASEAPPTSHRRASRQRPGPDAARSQSVRGRLDDDDEVPRGPPQARQGGYLGPVDARAILGRVGGSRVAPSPLFLEELQYEEDDYPEDVGPEDGGGARSPPKVEVLEGRVPGPELRAAFPLDRLAPQVAVWDESVRSALALGHPAGFYPCPDSAFGLSRVGVMHFASPDNPAVFFRQTLQQGEALAWYITGDGILDLTDRRTKTSPAQAMSFLADAVVRLAINGWVCGTRLHAEARGSDLDDRAAELRRQFASLTALRPVGAAAVPLLSAGGLVSPQSGPDAAVFRSSLGSLLYWPGVRALLDRDCRVAARYAGRMTYLATGALLARFNPDAVRCVLTREAAFLGRVLDVLAVMAEQTVHWLSVVVGARLHPHVHHPAFADVAREELFRALPLGSPAVVGAEHEALGDTAARRLLANSGLNAVLGAAVYALHTALATVTLKYARACGDAHRRRDDAAATRRILAAGLVLQRLLGFADTVVACVTLAAFDGGFTAPEVGTYTPLRYACVLRATQPLYARTTPAKFWADVRAAAEHVDLRPASSAPRAPVSGTADPAFLLKDLEPFPPAPVSGGSVLGPGVRVVDIMSQFRKLLMGDEGAAALRAHVSGRRATGLGGPPRP", "output": "Tegument protein that can bind to various RNA transcripts. Plays a role in the attenuation of selective viral and cellular mRNA degradation by modulating the activity of host shutoff RNase UL41/VHS. Also plays a role in the primary envelopement of virions in the perinuclear space, probably by interacting with two nuclear egress proteins UL31 and UL34."}]}
+{"id": "function_test_1260", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MISGILASPGIAFGKALLLKEDEIVIDRKKISADKVDQEVERFLSGRAKASAQLEAIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADAAAHEVIEGQATALEELDDEYLKERAADVRDIGKRLLRNILGLAIIDLSAIQEEVILVAADLTPSETAQLNLQKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTAQVKNGDYLILDAVNNQVYVNPTNDVIEQLRAVQEQVATEKAELAKLKDLPAITLDGHQVEVCANIGTVRDVEGAERNGAEGVGLYRTEFLFMDRDALPTEEEQFAAYKAVAEACGSQAVIVRTMDIGGDKELPYMNFPKEENPFLGWRAVRIAMDRKEILRDQVRAILRASAFGKLRIMFPMIISVEEVRALRKEIEIYKQELRDEGKAFDESIEIGVMVETPAAATIARHLAKEVDFFSIGTNDLTQYTLAVDRGNDMISHLYQPMSPSVLNLIKQVIDASHAEGKWTGMCGELAGDERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDELMTLVNKFIEEKTIC", "output": "General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)."}]}
+{"id": "function_test_1261", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRHSLPYRMLRKRPMKLSTTVILMVSAVLFSVLLVVHLIYFSQISDMTRDGLANKALAVARTLADSPEIRQGLQKKPQESGIQAIAEAVRKRNDLLFIVVTDMQSLRYSHPEAQRIGQPFKGDDILKALNGEENVAINRGFLAQALRVFTPIYDENHKQIGVVAIGLELSRVTQQINDSRWSIIWSVLFGMLVGLIGTCILVKVLKKILFGLEPYEISTLFEQRQAMLQSIKEGVVAVDDRGEVTLINDAAQELLNYRKSQDDEKLSTLSHSWSQVVDVSEVLRDGTPRRDEEITIKDRLLLINTVPVRSNGVIIGAISTFRDKTEVRKLMQRLDGLVNYADALRERSHEFMNKLHVILGLLHLKSYKQLEDYILKTANNYQEEIGSLLGKIKSPVIAGFLISKINRATDLGHTLILNSESQLPDSGSEDQVATLITTLGNLIENALEALGPEPGGEISVTLHYRHGWLHCEVNDDGPGIAPDKIDHIFDKGVSTKGSERGVGLALVKQQVENLGGSIAVESEPGIFTQFFVQIPWDGERSNR", "output": "Member of the two-component regulatory system DcuR/DcuS. Involved in the C4-dicarboxylate-stimulated regulation of the genes encoding the anaerobic fumarate respiratory system (frdABCD; nuoAN; dcuB; sdhCDAB; etc.). Weakly regulates the aerobic C4-dicarboxylate transporter dctA. Activates DcuR by phosphorylation."}]}
+{"id": "function_test_1262", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "VHWTAEEKSAITSIWNKVDVPAVGSEALSRLLIVYPWTQRFFTSFGNLSNAAAIQSNAQVKAHGKKVFTAFGDAVKNPEAVKETFAKLSELHCDKLHVDPINFKLLGQILITVLAAHFGKEFTPHVQASYQKLVSVVAHALAHRYH", "output": "Involved in oxygen transport from the lung to the various peripheral tissues."}]}
+{"id": "function_test_1263", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSRRGTAEKRTAKSDPIFRNRLVNMVVNRIMKDGKKSLAYQILYRAVKKIQQKTETNPLLVLRQAIRRVTPNIGVKTRRNKKGSTRKVPIEIGSKQGRALAIRWLLEASQKRPGRNMAFKLSSELVDAAKGGGGAIRKKEATHRMAEANRALAHFR", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit."}]}
+{"id": "function_test_1264", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIWHVQNENFILDSTRIFMKAFHLPLFDGSFIFPECILIFGLILLLMIDSTSDQKDISWFYFISSTSLVMSITALLFRWREEPMISFSGNFQTNNFNEIFQFLILLCSTLCIPLSVEYIECTEMAITEFLLFILTATLGGMFLCGANDLITIFVALECFSLCSYLLSGYTKKDVRSNEATTKYLLMGGASSSILVHGFSWLYGSSGGEIELQEIVNGLINTQMYNSPGILIALLFITVGIGFKLSPAPSHQWTPDVYEGSPTPVVAFLSVTSKVAASASATRIFDIPFYFSSNEWHLLLEILAILSMILGNLIAITQTSMKRMLAYSSIGQIGYVIIGIIVGDSNGGYASMITYMLFYISMNLGTFACIVSFGLRTGTDNIRDYAGLYTKDPYLALSLALCLLSLGGLPPLSGFFGKLHLFWCGWQAGLYFLVSIGLLTSVVSIYYYLKIIKLLMTGRNQEITPHVRNYRRPPLRSNNSIELSMIVCVIASTIPGISMNPIIEIAQDTLF", "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_1265", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSAADLDYFSEDEQREIEAELDTGFKDIEEKYAVTAQKGFETMLVVDNIPIVDGSKKQRLLERLRQTFAKVGAPIEEESIDMPWNAAAGTNKGFVFLTYPDVKEAENAVHTLDGVSFGKNVLHVNRFGDIQRFASMPVGEGDLPSGWKEKEYIEKDYLRNWLGDIAGRDQYVTFWETEVTVWWNGRNGTAEALKGPDGKPVKNSKWGELYLQWSTMGTYLASLHRVGVALWSGPKLDGPIGVNVLRFTHPNVRLIQFSPCENYLVTWSEDPLPNYENHPNAALRDTFGPEDEGNQYVIWDIKTTRVLRTFPGDKSAIGVDDTQSRMSWPTFKWSADDSYIAKCNVGAGISVYELPTMGLLDRKSIKIEGVQDFEWCPMSQKDLIARQEGKGKECVLAFWTPEAQNQPARVNIMAVPSRTILRSKNLFNVSECKFYWQSQGDFLCVKVDRHARKAKSKKATSCNLEIFRMREKDYPVEVLEFKDYVPQFAWEPSGTRFAIVLQAETNLPSVSGASTKYSIDFYQLDSKKGDFIAIKHLDSKMANTLVWSPKGRHIALATIGSSSKYDIEFWDLDFTIDERREAAELGANVTMLGTGEHYGITEIAWDPSGRYIATSASTWRQSPEPGFSIWDFKGQQLLHESRDRFKQFLWRPRPPTLLSKDQIKKVRKELREYSRQFDEEDAAEENRGSAEKLAQRRREIGEWNAWRTRNNDRLAFERENRGKSKAKIDVKGQEARVEEWVEELIDETEELSM", "output": "RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation."}]}
+{"id": "function_test_1266", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSKTIAINAGSSSLKWQLYQMPEEAVLAQGIIERIGLKDSISTVKYDGKKEEQILDIHDHTEAVKILLNDLIHFGIIAAYDEITGVGHRVVAGGELFKESVVVNDKVLEQIEELSVLAPLHNPGAAAGIRAFRDILPDITSVCVFDTSFHTSMAKHTYLYPIPQKYYTDYKVRKYGAHGTSHKYVAQEAAKMLGRPLEELKLITAHIGNGVSITANYHGKSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIEQDPELKDAADVVNMLNKKSGLSGVSGISSDMRDIEAGLQEDNPDAVLAYNIFIDRIKKCIGQYFAVLNGADALVFTAGMGENAPLMRQDVIGGLTWFGMDIDPEKNVFGYRGDISTPESKVKVLVISTDEELCIARDVERLKNTK", "output": "Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction."}]}
+{"id": "function_test_1267", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGTARFLSAVLLLSVLLMVTFPALLSAEYHDGRVDICSLPSDSGDCLRFFEMWYFDGTTCTKFVYGGYGGNDNRFPTEKACMKRCAKA", "output": "Dual-function toxin that inhibits both serine proteases and voltage-gated potassium channels (Kv)."}]}
+{"id": "function_test_1268", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTDIDYKLEAVPATRIAADDIDKTFRSSTIDLISGALGGKVLGFSDEWFAEAANLLTPTAPIRQPGKMVYTGAWYDGWETRRHNPAEFDWVVIRLGVASGTVEGVEIDTAFFNGNHAPAISVEGCFSQNDDEVLSWKGERGGWETILGVQECGPSQRFGWKLENPTKKQYTHVRLNMYPDGGIARFRLFGHAVPVFPDNTDAIFDLAAAQNGGVAISCSDQHFGTKDNLILPGRGKDMGDGWETARSRTKGHVDWTIIRLGAPGYIQNFMVDTAHFRGNYPQQVKLQAIEWKSEGEPGADSEGWTEVVEPIKCGPDQEHPVESLVKDKPFTHVKLIIVPDGGVKRLRVFAKRAV", "output": "Utilization of purines as secondary nitrogen sources, when primary sources are limiting."}]}
+{"id": "function_test_1269", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQLVRGLHNLRPEHRGCVATIGNFDGVHRGHQAILARLRERAVELGVPSCVVIFEPQPREFFTPETAPARLALARQAATAGGEGVDRVLCLAFNQRLRSLSAAEFVDRILVDGLGVQHLEVGDDFHFGCDRVGDFDFLQHAGVNQGFTVEAAQTVELDGLRVSSTQVRNALAAADFDLAERLLGRPFRIAGRVLHGQKLARQLGTPTANVQLKRRRVPLTGVYLVSVDIDGQSWPGVANIGVRPTVAGDGKAHLEVHLLDFAGDLYDRRLTVVFHQKLREEQRFASLEALKTAINADVAAARALAAPSAHR", "output": "Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD."}]}
+{"id": "function_test_1270", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDYGFATRAIHAGQDPESVTGAVIVPIYQTSTYAQRGVGDHTGYEYSRTDNPTRTALQTCLAALEEAKHALVFASGLGASTTLMLMLKAGDHVICGDDVYGGTYRLFQRVMTEHGLSFDFIDMADPEAVRAAIKPNTRLIWLETPTNPLLKLAPIAAITRVAREHGIWTIVDNTFASPYNQRPITLGADMVLHSTTKYIGGHSDVVGGAIMTSNDELYEKLKFLQNAAGAVPGPFDCWLVLRGVKTLSIRMRDDERNALAIAQFLTEHPGVEKVIYPGLPSHPQHNLAREQMRGFGGMISILLKGGAEAANAMVSKTKL", "output": "Catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction. In the absence of thiol, catalyzes gamma-elimination to form 2-oxobutanoate, succinate and ammonia (By similarity)."}]}
+{"id": "function_test_1271", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKPLKLKRLIMENNKSHATNLSLGGPFQGNCMPINQYFSKNQPNRGSSSSEKRSSLLPLWESKNAADGFSIVSHNVLLDGATTILNLNSFFECETGNYHTFCPISCVAWLYQKIEDSFFLVIGTKTCGYFLQNALGVMIFAEPRYAMAELEESDISAQLNDYKELKRLCLQIKQDRNPSVIVWIGTCTTEIIKMDLEGMAPRLETEIGIPIVVARANGLDYAFTQGEDTVLSAMALASLKKDVPFLVGNTGLTNNQLLLEKSTSSVNGTDGKELLKKSLVLFGSVPSTVTTQLTLELKKEGINVSGWLPSANYKDLPTFNKDTLVCGINPFLSRTATTLMRRSKCTLICAPFPIGPDGTRVWIEKICGAFGINPSLNPITGNTNLYDREQKIFNGLEDYLKLLRGKSVFFMGDNLLEISLARFLTRCGMIVYEIGIPYLDKRFQAAELALLEQTCKEMNVPMPRIVEKPDNYYQIRRIRELKPDLTITGMAHANPLEARGITTKWSVEFTFAQIHGFTNTREILELVTQPLRRNLMSNQSVNAIS", "output": "Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (ChlN-ChlB) is the catalytic component of the complex."}]}
+{"id": "function_test_1272", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MENDTWENESSASNHSIDETIVEIPGKYQTMEMIFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGVFSMNLYSLYIIKGYWPLGPIVCDLWLALDYVVSNASVMNLLIISLERXFCVTKPLTYPARRTTKMAGLMIAAAWLLSFELWAPAILFWQFIVGQRTVPSGECYIQFLSNPAVTFGTAIAAFYLPVVIMTILYIHISLASRSRVRRHCPETRQEKKKPISSMKSLLIKQTKNIPKQDAGDKVVEKKNGVSNGKIEKSMTNLQTAEEKETSNESSSASLSHNPPEKQPLSEASSGVVLAPTQSMPPLPAKANTASKWSKIKIVTKQTGNECVTAIEIVPECAIPLPEQANNRPVNVARKFASIARNQVRKKRQMAAREKKVTRTIFAILLAFIITWTPYNVMVLINTFCQTCIPETIWYIGYWLCYVNSTINPACYALCNATFKKTFKHLLMCQYKSIGTAR", "output": "The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase."}]}
+{"id": "function_test_1273", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MENLSERFNVLQDQLMNIYEAAEHTLETQIAHWTLLRREAVLLYYARQKGITRLGYQPVPTLAVSEAKAKEAIGIMLQLQSLQKSEYASENWTLVDTSAETYNNVPEHHFKKGPVPVEVIYDKEPENANVYTMWKYVYYMDPEDVWHKTTSGVNQTGIYYLHGDFKHYYVLFADGARMYSKTGQWEVKVNKETVFAPVTSSTPPGSPGQRDPDATSKTPATSSDSTTRSSDKQSQQADPRRKGYGRRPSSRTRRQETQQRRSRSRYRSQSNSRSRSQSQTRALGATSVSRSSRSPSVTQIRNRRSRSQSRGRGGRGSSTDTTTKRRRSRSSSSNTRKRSQRGERGRGERGGRGKRRDRSSSTSPTPKRSRAGSRSSRQRGVSPEQVGRSLQSVSSKHRGRLGRLLEEALDPPVIICKGGANTLKCFRNRARHKYTGLFKAFSTTWSWVAGDSTERLGRPRMLISFTSTNQRKDFDETVKYPKGVETAYGNLDSL", "output": "Plays a role in the initiation of viral DNA replication. A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity. Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA. E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome. Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box. Repression occurs by sterically hindering the assembly of the transcription initiation complex."}]}
+{"id": "function_test_1274", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MATPSMMPQWAYMHIAGQDASEYLSPGLVQFARATDTYFSLGNKFRNPTVAPTHDVTTDRSQRLTLRFVPVDREDTTYSYKARFTLAVGDNRVLDMASTYFDIRGVLDRGPSFKPYSGTAYNSLAPKGAPNSSQWLAKDTNAGDQALKTHTHGVAAMGGTDITAKGLQIGVDTTENKNEPIYANEIYQPEPQVGEENLQDVENFYGGRALKKETKMKPCYGSFARPTNEKGGQAKFLTDGDGQLTKNHDITMNFFDTPGGTVGQDTELEADIVMYAENVHLETPDTHVVYKPGTSDESSEANLVQQSMPNRPNYIGFRDNFVGLMYYNSTGNMGVLAGQASQLNAVVDLQDRNTELSYQLLLDSLGDRTRYFSMWNSAVDSYDPDVRIIENHGVEDELPNYCFPLDGAGTNATYQGVKVKNGQDGDVNADWEKDPNLASRNQICKGNIFAMEINLQANLWKSFLYSNVALYLPDSYKYTPANVTLPANTNTYEYMNGRVVAPSLVDAYINIGARWSLDPMDNVNPFNHHRNAGLRYRSMLLGNGRYVPFHIQVPQKFFAIKNLLLLPGSYTYEWNFRKDVNMILQSSLGNDLRVDGASVRFDSVNLYATFFPMAHNTASTLEAMLRNDTNDQSFNDYLSAANMLYPIPAKATNVPISIPSRNWAAFRGWSFTRLKTKETPSLGSGFDPYFVYSGSIPYLDGTFYLNHTFKKVSIMFDSSVSWPGNDRLLTPNEFEIKRSVDGEGYNVAQCNMTKDWFLVQMLSHYNIGYQGFHVPEGYKDRMYSFFRNFQPMSRQVVDEINYKDYKAVTLPFQHNNSGFTGYLAPTMRQGQPYPANFPYPLIGQTAVPSVTQKKFLCDRVMWRIPFSSNFMSMGALTDLGQNMLYANSAHALDMTFEVDPMDEPTLLYLLFEVFDVVRVHQPHRGVIEAVYLRTPFSAGNATT", "output": "Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid. Assembled into trimeric units with the help of the chaperone shutoff protein. Transported by pre-protein VI to the nucleus where it associates with other structural proteins to form an empty capsid. Might be involved, through its interaction with host dyneins, in the intracellular microtubule-dependent transport of incoming viral capsid to the nucleus."}]}
+{"id": "function_test_1275", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSWQTYVDDHLLCEIEGNHLTHAAILGQDGSVWAKSASFPQFKPEEITGIMNDFNEPGTLAPTGLYIGGTKYMVIQGEPGSVIRGKKGPGGVTVKKTNLALVIGIYDEPMTPGQCNMIVERLGDYLIEQGL", "output": "Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG."}]}
+{"id": "function_test_1276", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKTLPKERRYETLSYLPPLTDQQIAKQVEFLLDQGFIPGVEFEEDPQPETHFWTMWKLPFFGGATANEVLAEVRECRSENPNCYIRVIGFDNIKQCQTVSFIVHKPNQNQGRY", "output": "RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity."}]}
+{"id": "function_test_1277", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNRKRTIILDTETTGINQTSLPHINHRIIEIGAVEIIDRCFTGNNFHVYIQPGRSIESGALKVHGITNKFLLDKPIFKDIADSFLNYIKNSILVIHNASFDVGFINQELEILNKKIKINTFCSIIDTLKIARELFPGKKNTLDALCTRYKINKSHRNLHSAIVDSYLLGKLYLLMTGGQDSLFSDNTINYKENFKKLKKNIQLKNNTLRILHPTLKENDLHEKYLQYMKDKSTCLWN", "output": "DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease (By similarity)."}]}
+{"id": "function_test_1278", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEITSVNHICFSVSDLNTSIQFYKDILHGDLLVSGRTTAYLTIGHTWIALNQEKNIPRNEISHSYTHIAFSIDEEDFQQWIQWLKENQVNILKGRPRDIKDKKSIYFTDPDGHKIELHTGTLKDRMEYYKCENTHMQFYDEF", "output": "Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor."}]}
+{"id": "function_test_1279", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKDLTDKQQAVLAFITAIIKERGFPPTIREIGDEFGITAKGAYDHLKAIEKKGYLKTAKNQSRAIELIRQSPMESLPVQATSIPVIGQVAAGLPIFAEENIESYIPVPDEMAKGNVPMYALRVQGDSMIEVGINDGDIAIIEKRDIARNGEIVVALIEDEATLKVYYKEQDQIRLEARNPKYKPIKTKKATVMGKLIGLYRIY", "output": "Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair."}]}
+{"id": "function_test_1280", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGKSTLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTIYENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVARVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTGFFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG", "output": "Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system."}]}
+{"id": "function_test_1281", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTTVYYDQDVKTDALQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAEAVKQADVIMVLLPDEIQGDVYKNEIEPNLEKHNALAFAHGFNIHFGVIQPPADVDVFLVAPKGPGHLVRRTFVEGSAVPSLFGIQQDASGQARNIALSYAKGIGATRAGVIETTFKEETETDLFGEQAVLCGGVSKLIQSGFETLVEAGYQPELAYFEVLHEMKLIVDLMYEGGMENVRYSISNTAEFGDYVSGPRVITPDVKENMKAVLTDIQNGNFSNRFIEDNKNGFKEFYKLREEQHGHQIEKVGRELREMMPFIKSKSIEK", "output": "Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate."}]}
+{"id": "function_test_1282", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSNFTAEDKAAITSLWGKVNVEDAGGETLGRLLVVYPWTQRFFDSFGSLSSPSAIMGNPKVKAHGVKVLTSLGEAIKNLDDLKGTFGQLSELHCDKLHVDPENFRLLGNVLVTVLAILHGKEFTPEVQASWQKMVAGVASALASRYH", "output": "Gamma chains make up the fetal hemoglobin F, in combination with alpha chains."}]}
+{"id": "function_test_1283", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAKLTGMFSAAILLSMAICSTAIIYRGEHMSMYLNASSEFAVYPTDQSLVLVGHLLFLDGQRLPTTNYSGLIELIHYNYSSVCYTVIQTISYESCPRVANNAFRSCLHKTSKHYHDYFRVNASVETNVLLNITKPQPTDSGAYILRVKLDHAPTADVFGVSAFVYDLKSKTVPDPMPTTQTVEPTTSYVSTPTYDYTDDVTTETESTSTSTQQAMTSTQTPSATWGTQLTTELPTNETVVIGQEALLCHWFQPSTRVPTLYLHLLGRTGNLPEDVLLVEDSEFLRTTSPAHRPSASPADGDDFKQTNSTSLKARNKIVAMVVIPTACVLMLLLVVVGAIINGAVRKHLLSCASRRIYRSGQGGASAAERRRLTCGPTLAASSESLADDTTSSPPTPKPSKKTKLETDPLMEQLNRKLEAIKEES", "output": "In epithelial cells, the heterodimer gE/gI is required for the cell-to-cell spread of the virus, by sorting nascent virions to cell junctions. Once the virus reaches the cell junctions, virus particles can spread to adjacent cells extremely rapidly through interactions with cellular receptors that accumulate at these junctions. Implicated in basolateral spread in polarized cells. In neuronal cells, gE/gI is essential for the anterograde spread of the infection throughout the host nervous system. Together with US9, the heterodimer gE/gI is involved in the sorting and transport of viral structural components toward axon tips."}]}
+{"id": "function_test_1284", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "TQRDTLTKGMTQGQIVAGPDDTKIDQSIMDQGVCATIALPFDIHVAQSVKNVMFMFAWTQKHGLAVNNLVILGVPGYLNMWKRFGESTDEPSESSKRCCYEKPTDPVSGEIVTPAFDPADEISEITHQEESADIKPVRLLDARLLGYTWVTQNHSWIVAYSDEPIKDGNEVVTLRNIGNNNFCDALRKCTDKSACIHQYLQFAWNSFGDPTVRTRQVVFEVVGWADSDTTNNNSDTLFYRTTQADNWQVLTESKTNTIGLAEVDWFNFKYETKQEVSIEIARQTWTSTLNAGVSTVSRVPKVPIKVKINVDTFLKVLFAVYKADLYDIFLQFASVFKKGGNRQYWLNYTQEPNTKSNYNHKIYNDKIRYLQEDVQVHPNETQSKWWWWSFKKVALTTMTVVALTRFKASGINGQYISARQFSGGETVSPYRLAAPFDSCLWRRSPNPLGTDGLKVALAHHPLAGASNRNKLRVSIPAQCICSITA", "output": "Cytolytic protein with insecticidal activity. Acts as a pro-inflammatory agent."}]}
+{"id": "function_test_1285", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "PGITXTSLHVAPGARLAVKGDIPAGAKSWVINLGKGENDIMLHFNARFDAHGDIRTIV", "output": "May regulate cell apoptosis and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates (By similarity)."}]}
+{"id": "function_test_1286", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "FLPFIAGMAANFLPKIFCAISKKC", "output": "Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli."}]}
+{"id": "function_test_1287", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "GKFSVFGKILRSIAKVFKGVGKVRKQFKTASDLDKNQ", "output": "Disrupts biological membranes, particularly those rich in phosphocholine. Has antimicrobial activity against Gram-negative bacterium E.coli, Gram-positive bacteria B.subtilis and S.aureus, and hemolytic activity against sheep, pig and guinea pig red blood cells. Has insecticidal activity against S.frugiperda ovarian cells by opening non-selective ion channels. Enhances the insecticidal activity of spider venom neurotoxic peptides."}]}
+{"id": "function_test_1288", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "ADCLNEGDWCADWSGPSCCGEMWCSCPGFGKCRCKK", "output": "Binds at site 4 of sodium channels (Nav) and inhibits the fast inactivation of cockroach channels. This toxin is active only on insects (By similarity). Has a potent activity against S.litura larvae."}]}
+{"id": "function_test_1289", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "PALIPFPRV", "output": "Mediates visceral muscle contractile activity (myotropic activity)."}]}
+{"id": "function_test_1290", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "NYLHDTVGRLWGPSRAGLLDGLDWMVGDVQSR", "output": "Plasmin-like serine protease. Has fibrinolytic and fibrinogenolytic but not plasminogenolytic activity. Cleaves after Arg and Lys residues."}]}
+{"id": "function_test_1291", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "RIRYKGIVCDRCGVEVTSSKVRRERMGHIELAAPVTHIWYFKGIPSRMGLILDMSPRSLEEIIYFASYVVINPGNTPLEKKQLITEAEYRQYQDQYGTDTFDAKMGAEAIKELLAEVDLEKHAKELKNELKDATGQKRTRAVRRLDIVEAFIQSGNKPEWMVMDVVPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVSGPGNRPLKSLSHLLKGKQGRFRQNLLGKRVDYSGRSVIDVGPFLKMNQMGLPRQMAVELFKPFIYNRLIELGTENGGANNLRSARRLVERHEDVVQDVLEEVVKEHPVLLNRAPTLHRLGIQAFEPVLVSGKAMRLHPLVTTAYNADFDGDQMAIHVPLSDEAQAEARLLMLAASHILAPKDGKPIVAPSQDMTIGNYYLTTEEAGIKGEGMIFSSADEVKMALQNHEVELHTRIGIAASSFDKAKPFTDHQRARIMVTTVGKVIFNEILPDDFPYINEPKSENFNGIDGRFFLDPGTDIVGWFKNESLNGPFKSGFLSDIIAQIYARYQVTRTSVLLDDMKDLGYNISTRSGLTVRMSDVTELPEKGEVLKEAHEKVAKITKQFRRGLLTDDERYIQVTQTWSDAQDKIKSMLIASFDSKNPIFMMSDSGARGNISNSFQLAGMRGLMAAPNGKVIELPVTANFREGLCVLEMFISTHGARKGMTDTALKTANSGYLTRRLVDVAQEVIVREEDCGTDRGLDVSAIMDGNEVIEPLYDRILGRYAMKPVIDPKTGEVIAKKNQMIDEHVADQIIDAGIQTVTIRSIFTCRTEHGVCVKCYGRNMATGDIVEVGEAVGTVAAQSIGEPGTQLTMRTFHTGGVALSEDITQGLPRVQEIFEARNPKGRAEISEVTGKVTSIEENPADRTKTVTIEGETDTREYVLPISARLRVAEGDEIHRSEAINEGPLDPKELIKVSSTLKTENYMLAEVRKVYRMQGVGIA", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_1292", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPPTVIAEPVASGAHASYSGGPGETDYHALNAMLNLYDADGKIQFDKDREAAHQYFLQHVNQNTVFFHNQDEKLDYLIRENYYEREVLDQYSRNFVKTLLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLERFEDRVVMVALTLAAGDTALAELLVDEIIDGRFQPATPTFLNSGKKQRGEPVSCFLLRVEDNMESIGRSINSALQLSKRGGGVALLLTNIREHGAPIKNIENQSSGVIPIMKLLEDAFSYANQLGARQGAGAVYLHAHHPDIYRFLDTKRENADEKIRIKTLSLGVVIPDITFELAKRNDDMYLFSPYDVERVYGVPFADISVTEKYYEMVDDARIRKTKIKAREFFQTLAELQFESGYPYIMFEDTVNRANPIDGKITHSNLCSEILQVSTPSLFNEDLSYAKVGKDISCNLGSLNIAKTMDSPDFAQTIEVAIRALTAVSDQTHIKSVPSIEQGNNDSHAIGLGQMNLHGYLARERIFYGSDEGIDFTNIYFYTVLYHALRASNRIAIERGTHFKGFERSKYASGEFFDKYTDQIWEPKTQKVRQLFADAGIRIPTQDDWRRLKESVQAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRKEGKIGRVYYPAPYMTNDNLEYYEDAYEIGYEKIIDTYAAATQHVDQGLSLTLFFKDTATTRDVNKAQIYAWRKGIKTLYYIRLRQMALEGTEVEGCVSCML", "output": "Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)."}]}
+{"id": "function_test_1293", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAITDVDVFAHLTDADIENLAAELDAIRRDVEESRGERDARYIRRTIAAQRALEVSGRLLLAGSSRRLAWWTGALTLGVAKIIENMEIGHNVMHGQWDWMNDPEIHSSTWEWDMSGSSKHWRYTHNFVHHKYTNILGMDDDVGYGMLRVTRDQRWKRYNIFNVVWNTILAIGFEWGVALQHLEIGKIFKGRADREAAKTRLREFSAKAGRQVFKDYVAFPALTSLSPGATYRSTLTANVVANVIRNVWSNAVIFCGHFPDGAEKFTKTDMIGEPKGQWYLRQMLGSANFNAGPALRFMSGNLCHQIEHHLYPDLPSNRLHEISVRVREVCDRYDLPYTTGSFLVQYGKTWRTLAKLSLPDKYLRDNADDAPETRSERMFAGLGPGFAGADPVTGRRRGLKTAIAAVRGRRRSKRMAKSVTEPDDLAA", "output": "Is likely involved in the aerobic desaturation system responsible for the synthesis of oleic acid from stearoyl-CoA; oleic acid is a precursor of mycobacterial membrane phospholipids and triglycerides. Catalyzes the conversion of stearoyl-CoA to oleoyl-CoA by introduction of a cis double bond between carbons 9 and 10 of the acyl chain. Requires the electron transfer partner Rv3230c to pass two electrons from NADPH to its active site diiron center. Is also able to catalyze the 9-desaturation of palmitoyl-CoA to palmitoleoyl-CoA."}]}
+{"id": "function_test_1294", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLIGSHVSPTDPLAAAEAEGADVVQIFLGNPQSWKAPKPRDDAAALKAATLPIYVHAPYLINLASANNRVRIPSRKILQETCAAAADIGAAAVIVHGGHVADDNDIDKGFQRWRKALDRLETEVPVYLENTAGGDHAMARRFDTIARLWDVIGDTGIGFCLDTCHTWAAGEALTDAVDRIKAITGRIDLVHCNDSRDEAGSGRDRHANLGSGQIDPDLLVAAVKAAGAPVICETADQGRKDDIAFLRERTGS", "output": "Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate."}]}
+{"id": "function_test_1295", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVKLALVVIFLLLASLFQPLTAQSSCPGNKKETWPELIGVPAKFAREIIQKENSKLTNVPSVLNGSPVTKDFRCERVRLFVNVLDFVVQIPRVG", "output": "Stress response. Inhibits trypsin. May play a role in the reentering of protoplasts into the cell cycle."}]}
+{"id": "function_test_1296", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDILKDKIRSEGIVLSEHVLKVDAFLNHQIDPQLMQQVGHAFAMRFRDQGITKIVTIEASGIAPAVMAGLELGVPVIFARKYQSLTLKDNLYISKVFSFTKQTESTIAISAKHLNAHDHVLVIDDFLANGHAAKALIDLIGQAGASIAGLGIVIEKSFQDGRALLESEGYRVESLARVKSLAGGQVEFLD", "output": "Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis."}]}
+{"id": "function_test_1297", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSEPRKILVTSALPYANGSIHLGHMLEYIQTDMWVRFQKMRGNQAVYVCADDAHGSAIMLRAEREGITSEQLIDAVRAEHMGDFADFLVDFDNYHSTHSEENRELSSAIYLKLRDAGHIDTRPVTQYFDPEKQMFLADRFIKGTCPKCGTADQYGDNCEACGATYAPTELKDPKSAISGATPVLKESLHYFFKLPDFEAMLKQWTRSGALQESVANKLAEWLDSGLQQWDISRDAPYFGFEIPDAPGKYFYVWLDAPIGYMASFKNLCARRPELDFDAFWGKDSSAELYHFIGKDIVNFHALFWPAMLEGAGYRKPTALNVHGYLTVNGQKMSKSRGTFVKARTYLDHLDPEYLRYYYASKLGRGVEDLDLNLEDFVQKVNSDLVGKVVNIASRCAGFIHKGNAGVLVGADPAPELLAAFREAAPGIAEAYEARDFNRAMREIMALADRANAWIAEQAPWALAKQEGQQDKVQAVCGLGINLFRQLVIFLKPVLPKLAAAAEAFLNVAPLTWADHRTLLANHQLNPFQPLMTRIEPAKVEAMIEASKEDLAAAASQPAGNGELVKEPIAAEIDFDAFAAVDLRIALIEKCEFVEGADKLLRLSLDIGDAKRNVFSGIKSAYPDPSALEGRLTLYVANLAPRKMKFGVSEGMVLAAGPGGEEIYLLSPDSGAKPGQRVK", "output": "Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation."}]}
+{"id": "function_test_1298", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MMDQSIADAFPEVQVLEHEPLSKYTNTQTGGPADLLVFPESVTETKRLVLWAKETDTPLTIIGNASNLIVRDGGIRGLTLILTKMDDIQVNGNEVVAEAGAALIQTTEVAYQAGLTGLEFAAGIPGSIGGAVFMNAGAYDGEISEVVTSAEILTRDGEIKNLNNHELDFGYRHSSVQDYQDVVLSATFKLRSGDANKIRARMDELNRLRASKQPLEYPSCGSVFKRPTGYFTGKLIHEAGLQGFTVGGAQVSMKHAGFIINVGGATATDYMDVIHHVQATVLKQFGVTLETEVRIIGEEK", "output": "Cell wall formation."}]}
+{"id": "function_test_1299", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MFSRDMTIASFDPELSEAMEAERRRQEDHIELIASENYASPRVLEAQGSVLTNKYAEGYPGKRYYGGCEHVDEAERLAIERAKQLFGADYANVQPHSGSQANAAVYLALLQPGDTILGMSLDHGGHLTHGAKVNFSGRLFNAVQYGVCPDTGELDYAQLERLAKEHQPKMIIGGFSAYSRVVDWQRLRDIADSVGAYLLVDMAHVAGLVAAGVYPSPVQIADVTTTTTHKTLRGPRGGLILARANAEVEKKLNSLVFPGTQGGPLMHAIAGKAVAFKEALEPEFKAYQQQVVANARAMAQGLIERGYKVVSGGTDNHLFLIDLVDKGLTGKAADAALGKAHITVNKNTVPNDPQSPFVTSGLRIGTPAITTRGFKEEECRELAGWMADVLDDIENEDVIARVREQVTQVCRRLPVYQQG", "output": "Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism."}]}
+{"id": "function_test_1300", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVAFMNSATFVAGLFTLWSRPIWATPASNTNAVVVNGTAFTLNGDHVSYRFHVDDATGDLFSDHFGPRVSGNFPTEIVSQVNGWVNTIGRVRREFPDQGRGDFRIPAIRIRQTAGYTVSELLYRSHTVIPGKPALPGLPATFGSEEDVTTLVVHLYDEISEVAADLSYSIFPKYDAVVRSVNVTNQGAGNITIETLASLSVDFPYEDLDMVYLRGDWAREAHSERRKVEYGTQGFDSSAGYSSHLHNPFLAIMNPATTESQGETWGFSLVYSGSFAVNVERGSQGFTRALLGLNPGQLSWVLRPGESLVSPECVAVYSADGIGGMSRLLHRLYRNHLIKSKFAVSDRPVLLNSWEGLGFNYNETTVYQLATEAAELGVKLFVLDDGWFGDKYPRTADNAGLGDWVPNPDRFPHGLPHEVDRITALHPGNDTSTNLRFGLWFEPEMVNPNSSLYHQHPDWALHAGSYPRTLTRNQLVLNMALPEVQDYVIKSVSDILDSADISYVKWDNNRGIHETPSPSTDHQYMLGMYRVFDNLTTKYPNVLWEGCASGGGRFDPGVLQYFPQIWTSDDTDALERITIQMGTSLAYPPSAMGAHLSAVPNQQTGRTLPITFRAHVAMMGGSFGLELNPAHMPDDERDAVPGLIALAERVNPIVLTGDMYRLSPHDSQWPAVLFISPDGEQAVLFYFQTSPRVDNSIPRVKMQGLDPQAVYSVDGDAEYSGATLMNVGLQFPFDSDVGSKVVFFQRL", "output": "Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides."}]}
+{"id": "function_test_1301", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEHTYQYAWIIPFVPLPVTMSIGLGLLLVPTATKNLRRMWAFPSVSLLSIVMVFSADLSIQQINGSSIYQYLCSWTINNDFSLEFGHLIDPLTSIMSILITTVGIMVLIYSDNYMSHDQGYLRFFAYMSFSNTSMLGLVTSSNLIQIHIFWELVGMCSYLLIGFWFTRPIAANACQKAFVTNRVGDFGLLLGILGFYWITGSLEFRDLFEIFNNLIHTNGVNSLFATLCAFLLFVGAVAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLLPIFTVIPYIMNLISLLGIITVLLGATLALAQKDIKRSLAYSTMSQLGYTMLAPGIGSYRAALFHLITHAYSKALLFLGSGSIIHSMEPIVGYSPDKSQNMVLMGGLTKYVPITKTTFLLGTLSLCGIPPLACFWSKDEILNDSWLYSPIFAIIACSTAGLTAFYMFRMYLLTFEGHLHIRFQNYSGTKNSSFCSISIWGKEGPEPVKKKLLLSVMNNNQKVSFFSKKIYQIDGNVRNLMRSFSTHFDNKDTSMYPCESDNTMLFPLLVLVLFTLFVGSIGIPFDQVGSDFDILSKWLTPSINLLHQNSNYSVDWYEFVTNAIYSVSISYFGIFIASLLYGSVYSSFQNLDLINSFVKIGPKRLFLDRIINVIYNWSYNRGYIDVFYATFLTKGIRGLAELTNFFDRRVIDGITNGVGIASFFVGEGIKYVGGGRISSYLFVYLSYVSTFLLIYYFYFLNR", "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity)."}]}
+{"id": "function_test_1302", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSKVTSSTLLKYKQEGRKFTALTAYDASFASAFDGEGIDVLLVGDSLGMVLQGHDDTLPVTTADIAYHTRCVRRGIERSLLIADMPFMSYATPEQAMENATALMQAGANMVKLEGGHWLLETVTKLTERGIPVCAHLGLTPQSVHVFGGFKVQGRDAENAQRILDEAKALEAAGAQLLVVECIPESLATAITQALTIPVIGIGAGATTDGQILVMHDVLGISSGYIPRFSKNYLKQTGEIRSAVRAYIEEVANGTFPSSEHTFS", "output": "Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate."}]}
+{"id": "function_test_1303", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTVARNRAGAGPGKGSPISSFADKTFTDPARIRNFCIIAHIDHGKSTLADRMLQLTGVVEERQMRAQYLDRMDIERERGITIKAQNVRLPWKVGDEEFVIHLIDTPGHVDFTYEVSRALEACEGAVLLVDAAQGIEAQTLANLYLAMEKDLTIIPVLNKIDLPAADPDRYAEEIAHITGCEPGDVLRVSGKTGIGVKELLDEVVRQVPAPVGDPDGPARAMIFDSVYDAYRGVVTYVRVVDGRISPREKITMMSTGTTHDLIEVGIISPEPKASIGLGVGEVGYLITGVKDVRQSRVGDTVTAARGGATEPLVGYRDPKPMVYSGLYPLDGSDYPVLRDALDKLRLNDAALAYEPETSVALGFGFRCGFLGLLHMEITRDRLEREFGLELISTSPNVVYRVVMEDGSEHVVTNPSYWPEGKIREVYEPMVKCTIIAPSEFIGAIMELCQNRRGELGGMDYLSETRVELRYEMPMGEIMFDFFDALKSRTKGYASLDYEESGEQQADLVKVDILLQGEAVDAFSSIVHRSAAGAYGGRMTSKLRELIPRQQFEVPIQAAIGSKIISRENIRAIRKDVLAKCYGGDISRKRKLLEKQKEGKKRMKTIGRVEVPQEAFVAALSSESVGDKPKK", "output": "Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner."}]}
+{"id": "function_test_1304", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRAYWFDNLEGDQRQPHDSGRAVDPAYLSKLGVLYHHISSQSEVDELAKARDYKNRDEITVSPEKMGDIYEEKVKSFFHEHLHEDEEIRYILDGAGYFDVRSEGDDWVRIWLEKGDLIILPSGIYHRFTTDEQNYTKAMRLFKDEPKWTPLNRGEETDENQFRQEYLKLRQGLAA", "output": "Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway."}]}
+{"id": "function_test_1305", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGKLSMLYNAAIASTFVKVFLFPSYRSTDFEVHRNWLAITHSLPISEWYKSSISEWTLDYPPFFAYMECVLSWIAYFFGFDKAMLDPYNLNYVSPSTVVFQRGSVIVLELVLLFALREYVLSSNVKDQRNALLTAIDIFLSPGLLIIDHIHFQYNGFLFGLLLWSIVLAKPEKNMLLSAAIFSALICFKHIFLYVAPAYFVYLLRVYCFTPNFRPQFLNILKLGSTVISIFLLAFGPWIYMKQIPQLLSRLFPFSRGLCHAYWAPNFWALYSFVDRVAFAVLPRFGYALNQGTSINAPTRGLVGESSFAVLPNIPPALTFYICLGLQITVLIKLFIKPTWRVFVGAVTLCGWISFLFGWHVHEKAILMVILPFSILSLIDRRYLEAFRPLAVSGYLSLLPLLFTLNEAPIKYLFTGAWIAMLLTFDKCAPVPVKRVFLLNRVNIAYISGFVPLFIYNCFIHKLVMGDKFEFLPLMLLSTYAAWGIFWSFVSLLWLYFTDLK", "output": "Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol (By similarity)."}]}
+{"id": "function_test_1306", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTYQKLNVNTYSNLQIFNMPDLIEIQRASFRWFLEYGLIEELDSYSPITDYTGKLELHFIAKNYKLKQPKYSVEESKRRDSSYAVQMYVPTRLINKETGEIKEQEVFIGDLPLMTDRGTFIINGAERVIVNQIVRSPGVYYKSETDKSGRRTYNASLIPNRGAWLKFETDKNDLVWVRIDKTRKLSAQVLLKALGLGDSEIFDSLRHPDYFQKTIEKEGQYGEEEALLELYRKLRPGEPPTIAGGEQLLHSRFFDQKRYDLGQVGRYKLNNKLRLNLPNTVRVLTKEDILASIDYLINLEYDIGQTDDIDHLGNRRVRSVGELLQNQIRVGLNRLERIIRERMTVSESETLTPTSLVNPKPLVAAIKEFFGSSQLSQFMDQTNPLAELTHKRRISALGPGGLTRERAGFAVRDIHPSHYGRICPIETPEGPNAGLIGSLANHAKVNSYGFIETPYYPVENGRVLRDRTPIYMTADAEDDLRVAPGDIMTDAEGKILGDVVPVRYRQDFTTTNPQQVDYVAVSPVQVVSVATSLIPFLEHDDANRALMGSNMQRQAVPLLNPDRPLVGTGLEPQAARDSGMVVVTRTDGEVSYVDSTKISVIDKEGNQADYPLCKYQRSNQDTCLNQRPLVFEGDQVVAGQVLADGSSTEGAELALGQNVLVAYMPWEGYNYEDAILISERLVYDDVYTSIHIEKFEIEARQTKLGPEEITREIPNVGEDGLRNLDEQGIIRVGAWVQSGDILVGKVTPKGESDQPPEEKLLRAIFGEKARDVRDNSLRVPNGEKGRIVDVRVFTREKGDELPPGANMVVRVYVAQKRKIQVGDKVAGRHGNKGIISRILPIEDMPYLPDGTPIDVVLNPLGVPSRMNVGQIFECLLGWAGEILSVRFKCVPFDEMHGPEKSRETVHLMLKLARDNSGKDWVFDEKHPGKIWVFDGRTGERFDRPVTVGIAYMLKLVHLVDDKIHARSTGPYSLVTQQPLGGKAQQGGQRFGEMEVWALEAFGAAYTLQELLTVKSDDMQGRNEALNAIVKGKAIPRPGTPESFKVLMRELQSLCLDIAAHKVETVDDGTTQDVEVDLMADLPGKRTPSRPIYESLSTEGNQD", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_1307", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGRTQTVLALESSCDDTAAAVLRKGATGETQVLSSIVRGQDSLHAAYGGVVPEIAARAHAEILDICVEDALQAAQTSLHDVDAIAVTAGPGLIGGVVSGVMCAKGLALATGKPLYGINHLAGHALTPRLTDNVPFPYLMLLVSGGHCQFLLIKGPDDFKRIGGTIDDAPGEAFDKIARLLALPQPGGPSVERSARQGDAKRFSLPRPLLDRPGCDMSFSGLKTAVLRVRDGLVQDQGGLYPQDQADLSAGFQAAVVDVLAEKTSRAMQQYQQLSPTTATLCVAGGVAANMAIRTRLETVARDNGAVFVAPPLALCTDNAAMIGFAALERMADHPPDDLTLAARPRWPLDSKSPAMLGSGKKGAKA", "output": "Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction."}]}
+{"id": "function_test_1308", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKNINPSQTAAWKALQQHFEQMKDVTISSLFAKDDQRFNRFSATFDDQMLVDFSKNRITSETLEKLQDLAKETDLAGAIKSMFSGEKINRTEDRAVLHIALRNRSNTPIVVDGKDVMPEVNAVLAKMKQFCDRVISGDWKGYTGKAITDVVNIGIGGSDLGPYMVTEALRPYKNHLNMHFVSNVDGTHIAEALKPLNPETTLFLVASKTFTTQETMTNAHSARDWFLSAAGDPAHVAKHFAALSTNAKAVGEFGIDTNNMFEFWDWVGGRYSLWSAIGLSIALSVGFEHFEQLLSGAHAMDKHFAETPAEKNLPVLLALIGIWYNNFFGAETEAILPYDQYMHRFPAYFQQGNMESNGKYVDRNGHPVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKLIPCDFIAPAISHNPLSDHHAKLLSNFFAQTEALAFGKSLEDVEAEFAAAGKTPEQVAHVAPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIYTFDQWGVELGKQLANRILPELADDQEVTSHDSSTNALINRFKNWR", "output": "Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate."}]}
+{"id": "function_test_1309", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSQEKYIMAIDQGTTSSRAIIFNQKGEKVSSSQKEFPQIFPHAGWVEHNANQIWNSVQSVIAGAFIESSIKPSQIEAIGITNQRETTVVWDKKTGVPIYNAIVWQSRQTAPIAEQLKQDGHTKMIHEKTGLVIDAYFSATKIRWILDHVPGAQERAEKGELLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKDLTWDDEILELLNIPKDMLPEVKSNSEIYGKTAAFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNTGDEMQLSSNNLLTTIGYGINGKVHYALEGSIFIAGSAIQWLRDGLKMIETSPESEQFALASTSDDEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTSKEDFVKATLQSIAYQVRDVIDTMQVDSGIDIQQLRVDGGAAMNNMLMQFQADILGIDIARAKNLETTALGAAFLAGLAVGYWEDMDALKELNATGQLFKASMNESRKEKLYKGWKRAVKATQVFTQEEDADDDAK", "output": "Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate."}]}
+{"id": "function_test_1310", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKFNQFAHVKVPFEQKLAELNRIAFLHAGDEDLASNHIYRLFLERAFPNFKTEAAKNHALSNLAATENADILTYLNSSKINARVFYAVGLQLLGFEAELDFDLKDPFSAMDKLNLPYQKEIHHRDDVINAWYDLLCTSTKKGQNLLDILANRGYFTQFYQLNLTEPIFFNGKAQPVFDTNKLIHEVVYVESELDTDQDGKRDLLKVIITRPAMTDNGMKVPTIFTASPYYLGTNDASAEKMMHSVDLPITRKEVKPLSYQDIEYHKPETKLPKKRPVVISTKNAEESWEHLFTYTFNDYMLARGFAVVYSGGVGTLDSDGYRTCGDEAETLGAKDVVEWLNGKRTAFTTKEANKAIPAWWSNGKVAMTGKSYLGTLATAAATTGVAGLETIISEAAISSWYDYYREGGLVIAPGGFPGEDADILAEECFSRQKSAGDYNHSKDGFNKFLSTITKDQDRTTGNYNTFWDARNYLKDVGNIKCDIVMVHGLNDWNVKLKNVFNLYNKLGDVEVTKKLILHQGQHIYINNFQSLDFTDMMNLWLSHKLYGVENNAKELLPDILVQNNTKESTWETYSSWQSKNFTKLYLNSDSLSAQKKENQTLEFSDHLPETTFKHYQTDIANWKEEILASTSPKLETNRLILTSKPLKHETLLKGVAKIKLKIASQLDHGLVSVKLVDYGDAKRLGATPTILERRGLDLGYHWKEDNLVEFKLAKETPFKMITQAHLNLQNRHNDFSTDELEANKFYDVEITTQPMFYHLPKGHKLGLVIYATDMEMTLQGNEENSYRIDTTGSYCLLPIEE", "output": "Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline."}]}
+{"id": "function_test_1311", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSIQTDDFAAPPPKRILSGAPASPNEEAVERALRPKLLDEYVGQAKVREQLEIFISAARMRDEALDHVLLFGPPGLGKTTLSHIIAHELGVNLRQTSGPVLEKPKDLAALLTNLEKNDVLFIDEIHRLSPVVEEILYPALEDYKIDIMIGEGPAARSIKLDLQPFTLIGATTRAGMLTNPLRDRFGIVARLEFYSPEELASIVRRSAGLLKVPTDEKGGFEIARRSRGTPRIANRLLRRVRDYADVKGAGEITLDIAHRALVMLDVDPQGFDLMDRKLLEAVIHRFDGGPVGLDNIAASIGEERETIEDVIEPYLIQQGYLQRTPRGRIATLAAYKHLGVTPPAAQSGGDMFGAMRPE", "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA."}]}
+{"id": "function_test_1312", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MQSYASAMLSVFNSDDYSPGVQQNIPALRRSSSFLCTESYNSKYQRETGENSKDSVQDRVKRPMNAFFVWSRDQRRKMALENPRMRNSEISKQLGYQWKMLTAAEKWPFFQEAQKLQAMHREKYPNYKYRPRRKANMLPKNCSLLPADPASVLCSEVQLDNRLYRDDCTKATHSTMEHQLGHLPPINAASSPQQRDRCSHWTKL", "output": "Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. Involved in different aspects of gene regulation including promoter activation or repression. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending. Also involved in pre-mRNA splicing (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity)."}]}
+{"id": "function_test_1313", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRTHYSSDINEKLQGQKVTVCGWVHRRRDHGGVIFLDIRDRTGLVQLVFNPDNDNFKVADSLRSEFVIKAEGVVNLRPEGQENKNISSGKVEIIGDSIEVINKSKTIPFQLDDFQSTGEDVKLKYRYIDLRRPEMQHKLITRSKAIRYVRNFLDNNGFLDIETPFLTKATPEGARDYLVPSRNFNGKFYALPQSPQLFKQLLMVSGFDRYYQIVKCFRDEDLRADRQPEFTQIDIEASFIDEAFIMSTMERMIAGLFKETIGVEFATPFQVMTFADAIDKYGSDKPDLRIPLEFVNIKEDMQNEEFKVFSGPANDPQSRVIALRISGGNDKLTRKMIDEYTKFVGIYGAKGLAYIKINSLSQGKEGLQSPIVKNISEETLFKVIEKTSAKEDDLLFFGAGKTKIVNDSMGALRAKIGEDLDLFNKDWAPLWVVDFPMFEKDDNRLYAMHHPFTAPKVSSVEDLVNTNPEELSSRAYDMVINGYEVGGGSIRIHKQDIQAKVFNLLGISDDEAREKFGFMLDALSYGTPIHGGIAFGVDRLIMLLTGTTNIRDVIAFPKTQTASCLMTEAPSTVSLEQLNELGIAVKKEER", "output": "Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn)."}]}
+{"id": "function_test_1314", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTIQKNWQELIRPNKLQVTAGSDATRFATLVAEPLERGFGQTLGNALRRVLLSSLQGAAVQSVHIDGVLHEFSSIAGVREDVTDIVLNIKDISLKMQGEGPKRMVVKKQGPGVVTAGDIQTVGDIVVLNPDLQICTLDEGAEIRMEFTVNTGKGYVAAERNRPEDAPIGLIPVDSLYSPVRKVSYKVENTREGQILDYDKLTMTVETNGALTPDDAVAFAARILQDQLNVFVNFEEPRKEVTQEIIPDLAFNPAFLKKVDELELSVRSANCLKNDNIVYIGDLVQKSEAEMLRTPNFGRKSLNEIKEVLAQMGLHLGMEVPGWPPENIDELAKRFEDHY", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_1315", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRHEQARQAAAQPQGRYVLPNIIEKTSRGEYGMDPYSKLLKERIVFLGVQIDDVSANDVMAQLLFLESEDPDRDISIYINSPGGSFTSLTAIYDTMQFVRPDISTICMGQAASAAAVLLAAGTPGKRFALENSRILIHQPSAQGEGQSSDIEIQAREILRMRSLLERMLAVHTGKKEEDIRKDIERDKIFSADEAKEYGLIDEVIKTRKSSRLATAR", "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins."}]}
+{"id": "function_test_1316", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTPRLSFHKYQGLGNDFILVDNRWQSQPCLSPEEAVALCNRRFGVGADGVIFLLPGQEGADFSMRLFNSDGSEAEMCGNGIRCLARFLQDLGIPGRDGAYQIHTLAGRIVPQVRADGLVTVDMGIPRLLAKQIPTTLVEPDEKVIRQPLAVAGREWRVTAVSMGNPHCVVFLEEEGSLEELDLAAVGPLFEHHPAFPERTNTEFVQVLSPTRLRLRVWERGAGATLACGTGACAVLVAAVLEERAESQATVELPGGNLEIRWDPSTQHVWMTGPALHVFSGTTAG", "output": "Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan."}]}
+{"id": "function_test_1317", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTTDTHTLHIEEILELLPHRFPFLLVDRVLDFEKGKFLRAVKNVSFNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSAGKLAPGELYYFAAIDEARFKRPVQPGDQMILEVEFIKERRGVARFKGVAKVDGEVACEASMMCARRREA", "output": "Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs."}]}
+{"id": "function_test_1318", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTNIHTDKILILDFGAQYTQLIARRIREIGVYCEIWAWDHDPSEIAGFGAKGIILSGGPESTTLPGAPVAPQEVFDSGLPVFGICYGMQTLAAQLGGATEAADQREFGHAEVDVIAADALFAGLTDHAGAPRLNVWMSHGDHVSQVPPGFTITATTDRIPVAAMSNEDKRWYGVQFHPEVTHTLQGQTLLRRFVVDICGCQTLWTAANIIDDQIARVREQVGDDDVILGLSGGVDSSVVAALLHKAIGDKLTCVFVDTGLLRWQEGDQVMAMFAEHMGVKVIRVNAADRYFAKLEGVSDPEAKRKIIGNLFVEIFDEESNTLANAKWLAQGTIYPDVIESAGSKTGNAHVIKSHHNVGGLPQHMKLGLVEPLRELFKDEVRRLGVELGLPRTMVYRHPFPGPGLGVRILGEVKREYAELLAKADAIFIDELRKADLYDKISQAFAVFLPVKSVGVVGDARAYEWVIALRAVETIDFMTAHWAHLPYDFLGTVSNRIINELRGVSRVVYDISGKPPATIEWE", "output": "Catalyzes the synthesis of GMP from XMP."}]}
+{"id": "function_test_1319", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNLIESARAGLITPEMEQVAVQEGVTPEFVRQGVADGTIVILRNARRQNVTPVGVGKGLRTKVSASVGLYGETGGIDVEVAKIKAAVEAGTDAIMDLSVSGDIEAMLAETLAVSPKPVGTLPLYQAMAEAGRKYGSSVNMRDEDLFDVIERHAAAGVDFLALHCGTTMNIVERARNEGRIDPLVSYGGSHLIGWMLANRRENPLYEHFDRVLAIARKYDVTISFADGMRPGCLADSLDGPQVEELVVLGELVRRAREAGVQVMVKGPGHVPLQQLKATVVLEKSLCHGAPYFVFGPLVTDIAIGYDHINAAIGGALSAWAGAEFLCYVTAAEHVGIPDIDQVREGVIAARIAAHAADLANGLTCAREWDRELSRARKELDWKRQIALAIDPERAGRLREERSDAAAAGCAMCGKYCAMEIVSRYLGTARHTC", "output": "Together with BzaB, probably catalyzes the conversion of aminoimidazole ribotide (AIR) to 5-hydroxybenzimidazole (5-HBI) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Is thus involved in the anaerobic biosynthesis of the benzimidazole lower axial ligand of the cobamide produced by M.thermoacetica . Requires BzaB for catalytic activity, as BzaA alone displays no activity (By similarity)."}]}
+{"id": "function_test_1320", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSQSVLRLVDKDTMDKQKALEAAVGQIERAFGKGSIMKLGQRGSVVDIESISTGSLGLDIALGIGGLPRGRIVEIYGPESSGKTTLALHVVAEAQKKGGQCAFVDAEHAFDPLYARKLGVSLDDLLVSQPDTGEQALEIADTLVRSGAIDVLVIDSVAALVPKAELEGDMGDSHVGLQARLMSQALRKLTGTVSRSNTLIIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKDKEEVVGNQTRVKVVKNKVAPPFKVVEFDIMYGEGISKLGEMLDLGVKANIIEKSGAWFSYNSTRIGQGRENAKQFLRDNPAMAEEIENAVRANAGLIAEEMIGGPGGEDDDAGGAAGVGDEA", "output": "Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage."}]}
+{"id": "function_test_1321", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSKLADLRQEYARAELSRDHVTDDPIEQFRAWFDEAEDAELEEPNAMTLATAATDGTPSARIVLLKGLDDRGFHFYTNYESRKGTDLSQNPHAALVFLWKPLERQVRIEGTVERLPAEESTEYFHRRPRGAQMGAWASPQSRVVDSRADLEENLDTVKAEYGDEDEIPRPSHWGGYVVRPTEVEFWQGRPNRLHDRLRYRRSDPAGDWTLERLAP", "output": "Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)."}]}
+{"id": "function_test_1322", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKLLTVAFSLLLLGQVHASPLVLDKRSSCQLGDVWDLNAADAACSASCAIQHGDKHGGHCDKNKVCVCN", "output": "Shows antibacterial activity against numerous Gram-positive bacteria (Probable). It selectively inhibits peptidoglycan biosynthesis through complex formation with the cell wall precursor lipid II (1:1 molar ratio) thus inhibiting cell wall synthesis ."}]}
+{"id": "function_test_1323", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAASTNRLRFLYSSARTVPQTGSITPISRRTYATTEPSPSATGAPATARKRTNFTDKLNAGPSFADFVSGGEDNAPLEPSEAYALKTAMVGPAGRKKEMTRLPSWLKTPIPDSKNYQRLKKDLRGLNLHTVCEEARCPNISDCWGGSDKSAATATIMLMGDTCTRGCRFCSVKTNRRPPPLDPHEPENTAEAISRWSLGYVVLTSVDRDDLADGGARHFAETVIKIKQKKPSMLVECLTGDYLGDLEMVKLVARSGLDVYAHNVETVEALTPFVRDRRATFQQSLRVLEAAKQARPDLITKTSLMLGFGETEEQLWDALRQLRSVGVDVVTFGQYMRPTKRHMPVHEYVTPDQFELWRQRALDMGFLYCASGPLVRSSYKAGEAFIENVLKKRRAAGTAGESVTDSKAAVDEATR", "output": "Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives."}]}
+{"id": "function_test_1324", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAMNFVTFNQDYSYLAVATAKGFRIFTTDPFAKSYETKEGNIAIIEMLFSTSLVALILSPRRLQITNTKRQSTICELTFPTTVLAVKLNRKRLVIVLEDQIYLYDIQTMKLLYTIETSPNPSAICALSPSSDNCYLAYPLPHKAPPTSFTPPSHAPPGNTHISPTSGEVLIFDTLKLEAINVIEAHRSPLACITLNSDGTLIATASDKGTIIRVFSVPDGHKLYQFRRGSIPSRIYSMSFNTTSTLLCVSSSTETIHLFKLSQGQSSESSLPSPSAPQRSMSQSSLSNSPDEDETSGDKDSSEFHSRKHNGTLMGMLRRTSQTVGSSFAAKVGGYLPKGVSEMWEPARDFAWIKLPKSNPGPGGNGNTGPLRSVVAMSNNTPQVMVVTSDGNFYVFSIDLSKGGEGTLTKQYS", "output": "The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct atg9 trafficking to the pre-autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity)."}]}
+{"id": "function_test_1325", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGVSIVLGSQWGDEGKGKITDMLAQQATLCCRAAGGHNAGHTIVHGNKTYDFHILPSGLISPSCINLIGAGTVVHVPSFFKELASLEEKGLEGASKRIFISDRAHVCLQLHSVVDGLEEAKLGGRKVGTTGKGIGPCYSDKASRRGIRVGEILDEAVFERKLRSLDAGYRARFGDLEYNVEEELAQFKEYRKLLGPYIVDQLAFLQKYKDSPNTLVEGANALMLDLDHGTYPYVTSSSTGLGGAMQALSLNPTSIKSVIGVVKAYTTRVGSGPFPSEQFNADGDKLQSVGREFGVTTGRRRRCGWLDLVVCRYSQAINHYTALNLTKLDVLDDFDEIKVGVAYILPDGTRTENTIPADAEVLEKVKVEYVTLPGWKSNTMGVKKYEDLPDNARAYIEYIERELGGVPVKWIGTGPARDDMIARE", "output": "Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity)."}]}
+{"id": "function_test_1326", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MERIKELRNLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPSLRMKWMMAMKYPITADKRITEMVPERNEQGQTLWSKMSDAGSDRVMVSPLAVTWWNRNGPVTSTVHYPKVYKTYFDKVERLKHGTFGPVHFRNQVKIRRRVDINPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKKEELQNCKISPLMVAYMLERELVRKTRFLPVAGGTSSMYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRAAVSADPLASLLEMCHSTQIGGTRMVDILRQNPTEEQAVDICKAAMGLRISSSFSFGGFTFKRTSGSSIKREEEVLTGNLQTLKIKVHEGYEEFTMVGKRATAILRKATRRLVQLIVSGRDEQSIAEAIIVAIVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEHIDNVMGMVGVLPDMTPSTEMSMRGIRVSKMGVDEYSSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGTERLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQNPTMLYNKMEFEPFQSLVPKAIRGQYSGFVRTLFQQMRDVLGTFDTTQMIKLLPFAAAPPKQSRMQFSSLTVNVRGSGMRILVRGNSPVFNYNKTTKRLTILGKDAGTLIEDPDESTSGVESAVLRGFLILGKEDRRYGPALSINELSNLAKGEKANVLIGQGDVVLVMKRKRDSSILTDSQTATKRIRMAIN", "output": "Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription. Recognizes and binds the 7-methylguanosine-containing cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by the viral protein PA. Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex. In addition, participates in the inhibition of type I interferon induction through interaction with and inhibition of the host mitochondrial antiviral signaling protein MAVS."}]}
+{"id": "function_test_1327", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSKIVLDNVRKSYGGNIEVIKGVSLEIADGEFVVLVGPSGCGKSTLLRMIAGLESITSGTISIGERVVNNVEPAERDIAMVFQNYALYPHMTVRENLAYGLKNRKTPKEEIERRIAKAAKALEIEQFLERKPRQLSGGQRQRVAMGRAIVREPAAFLFDEPLSNLDAKLRVQMRVEIKRLQRSLGTTSVYVTHDQMEAMTMADRLVVLNAGHIEQVGTPIELYEKPASTFVATFIGSPSMNLLQSPESAPWQPGRAITLPSGGYTFGVRPEDIRILEEGDQDADGFNAQVRIEAVELVGAESYIHAALSDGKPLIFRVAGRSTHNIDEMVRVGASATDVHIFGADGRRVSD", "output": "Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Responsible for energy coupling to the transport system."}]}
+{"id": "function_test_1328", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDQSNRYADLSLKEEDLIAGQNHILVAYTMEPAAGYGYLEVAAHIAAESSTGTNVEVCTTDDFTKGVDAIVYDIDEANGIMKVAYPFDLFDRNGLDGKTMIVSFLTLAIGNNQGMGDVKNLQMFDFWVPETKLHLFDGPAVDITNMWKMLGRDKDNGGYIAGTIIKPKLGLRPEPFADAAYQFWLGGDFIKNDEPQGNQTFCPMKKVIPLVADAMKRAQDETGETKLFSANITADDHHEMCYRADYILETFGADAPQVAFLVDGYVGGPGMITTARRNYPSQYLHYHRAGHGAITSPSAKRGYTAFVLAKISRLQGASGIHVGTMGYGKMEGDASDKNIAYMIERDECQGPAFYQKWNGMKPTTPIISGGMNALRLPGFFENLGHGNVINTSGGGSYGHIDSPAAGATSLRQSYECWKSGADPIEFAKDHKEFARAFESFPADADKIYPGWREKLGVHK", "output": "RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site."}]}
+{"id": "function_test_1329", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNHSLKPWNTFGIDHNAQHIVCAEDEQQLLNAWQHATAEGQPVLILGEGSNVLFLEDYRGTVIINRIKGIEIHDEPDAWYLHVGAGENWHRLVKYTLQEGMPGLENLALIPGCVGSSPIQNIGAYGVELQRVCAYVDCVELATGKQVRLTAKECRFGYRDSIFKHEYQDRFAIVAVGLRLPKEWQPVLTYGDLTRLEPTTVTPQQVFNAVCHMRTTKLPDPKVNGNAGSFFKNPVVSAETAKALLSQFPTAPNYPQADGSVKLAAGWLIDQCQLKGMQMGGAAVHRQQALVLINEDNAKSEDVVQLAHHVRQKVGEKFNVWLEPEVRFIGASGEVSAVETIS", "output": "Cell wall formation."}]}
+{"id": "function_test_1330", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNFLVIGLSHKTAPVELRERISFSSDDPGGVLRAITALPGISEGMILSTCNRVEVYAASGDPAGGCACLQRFMAEHHGLDEAQLKPHLYIHSGRDAIRHLFRVASSLDSMILGEPQILGQLKEAYNLAESSCTAGPVLNRLLPRAFAAAKRVRNETAIAQHAVSVSYAAVELARKIFGDLAGKSVMIVGAGKMCELAARHLTGQNIGEVLVTNRTLARAQSLAEQFGGRAIPFAEFPLYLNQADIVLTSTAAGGLLLTRAQLEQIIRQRKNRPMFLIDIAVPRNIDPEVNHIDNVYLYDIDDLNGVIETNLRERRKAAKKAEDIIEQEIVRFYSWLRSLEATPMIVALRRQVEDIRRTETEKTLGSLQHLDAGDRRAVEALTRAIVNKVLHSPLSVLKRAGDDITGEIYLEAVRRLFDLNPDSQQTGGDSVEKDADSKQDLTS", "output": "Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA)."}]}
+{"id": "function_test_1331", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNIISVGVNHKTAPIEIRERISLSEVQNKEFITGLVSSGLAHEAMVLSTCNRTELYVVPAMHEVTGEFLKEYLISYRDARKEVRPEHFFSRFYCSTARHLFEVASAIDSLVLGEGQILGQVKNAYRIAAEAQCAGIMITRLCHTAFSVAKKVKTKTRIMEGAVSVSYAAVELAQKIFSNLSLKKVLLVGAGETGELAAKHMFAKNARNIVITNRTISKAEALAEELGTNQVLPYESYKEHLHEFDIIITAVSTKDYALTEADMQPAMARRKLKPVIILDLGLPRNVDPNISKLQNMFLKDIDDLKHIIDKNLEKRRRELPKVHAIIEEELIAFGQWINTLKVRPTIVDLQSKFIEIKEKELERYRYKVSEEELQRMEHLTDRILKKILHHPIKMLKAPIDTTDSIPSRVNLVRNVFDLEEPNQSHF", "output": "Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA)."}]}
+{"id": "function_test_1332", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNSSFSAPAKKSLGQHFLADRYYIDRIVQAVDPRAGQHLVEIGPGQGAITFPLLRRHGALTVIEFDRDLIAPLTEVAAPIGALSIIHRDVLSVDFTALANGTPIRLVGNLPYNISSPILFHALDHAAAVADMHFMLQKEVVDRMAAGPGSKVYGRLSVMLQAYCEVTALFVVPPGAFRPPPKVDSAVVRLVPRDPATVQINDRRRFADVVRAGFGQRRKTLRNALSTICEPAHFDAAQVRPDARAEQLEVADFIRLANVELA", "output": "Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits."}]}
+{"id": "function_test_1333", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGNHRSDLKATRRWVVKVGSALLTANGRGLDTGCIQELASHIARLRNKGYTIVLVSSGSVAAGMERLGWRRRPRALYELQAAAAVGQMGLIQAYESEFQHHNQHTAQILLTHEDLANRSRYLNARSTLRTLLRLGVVPIVNENDTVATEEIRFGDNDTLSALVANLVEAELLVILTDQEGLFDADPRHYPNASFISEAAANKTELDGMANSRAGALGRGGMITKIRAARRAARSGAITVIASGKEPKILQRIASGETVGTLLWPDRQPLAARKQWLAGQLQTKGRLWLDTGAVKVVREAGRSLLPIGVLACEGNFARGEVVSCLDSDAREIACGLVNYNAEETRRILGHSSHQIEQILGYVDEEELIHRDNLVLL", "output": "Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate."}]}
+{"id": "function_test_1334", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPAYRSRTTTHGRNMAGARALWRATGMKEGDFGKPIIAIANSFTQFVPGHVHLKDLGQLVAREIEKAGGVAKEFHTIAVDDGIAMGHSGMLYSLPSREIIADSVEYMVNAHCADALVCISNCDKITPGMLMAAMRLNIPAVFISGGPMEAGKVKIRGKSVSLDLVDAIVAAVDPAESDADVMAYERSACPTCGSCSGMFTANSMNCLTEALGLALPGNGSLLATHADRKELFLEAGRLIVALAKRYYEQDDETVLPRSIANFGAFENAMSLDIAMGGSTNTVLHLLAAAQEGGVDFTMADIDRLSRKVPNLCKVAPATPEYHMEDVHRAGGVISILGELDRAGLIHRQMATVHSPTLGAALDQWDIVRSSYEAAQSRYLAAPGGVPTQVAFSQGNRWESLDLDRAQGCIRDIAHAYSKDGGLAVLYGNLAKDGCIVKTAGVDPSILIFSGPARLFESQEAAIAAILGDKIQPGDVVLIRYEGPKGGPGMQEMLYPTSYLKSKGLGEVCALITDGRFSGGTSGLSIGHVSPEAAEGGTIGLVEEGDRIEIDIPHRRIHLAVDEEELAQRQRAMEAKAQQAWRPVNRNRTVSLALQAYAALTTSAAKGAVRDLGQLNRS", "output": "Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively."}]}
+{"id": "function_test_1335", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTATKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPALFDKAVGDAEDLSHALAFTSPKKIYAATYADCADADLVVITAGAPQKPGETRLDLVGKNLAINKSIVTQVVESGFNGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQALADKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVQLEQWLQENRDIDEQGLVDLFISVRDAAYSIINKKGATYYGIAVALARITKAILDDENAVLPLSVYQEGQYGDVKDVFIGQPAIVGAHGIVRPVNIPLNDAELQKMQASAEQLKDIIDEAWKNPEFQEASKN", "output": "Catalyzes the conversion of lactate to pyruvate."}]}
+{"id": "function_test_1336", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSQLPPAIFLMGPTAAGKTDLAIELTKVLPCELISVDSALVYRGMDIGTAKPSKELLAEFPHRLIDILDPAEAYSAADFRRDALEAMAEITARGKIPLLVGGTMLYYKALIEGLADMPAADPEVRAQIEEEAARLGWQALHDQLAAIDPESAARIHPNDPQRLSRALEVYRVSGQSMTELRLKQSVQSTEAAASGLQQLPYTVANLAIAPTNRQVLHERIKQRFTNMLEQGFIDEVVALRNRSDLHAGLPSIRAVGYRQVWDFLDGKLTSAEMQERGIIATRQLAKRQFTWLRSWKDLHWLDSLDCDNLPRALKYLGTISILS", "output": "Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)."}]}
+{"id": "function_test_1337", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSAKDVKFGVDARDKMLRGVDILANAVKVTLGPKGRNVVLEKSFGAPRITKDGVTVAKEIELDDKFENMGAQMVREVASKSADAAGDGTTTATVLAQAIVKEGAKSVAAGMNPMDLKRGIDLAVEAVVADLSRNSKKVTSNEEIAQVGTISANGDSEIGKFLADAMKKVGNEGVITVEEAKSLETELDVVEGMQFDRGYISPYFVTNAEKMRVEMDDAYILINEKKLSSLNELLPLLEAVVQTGKPLVIVAEDVEGEALATLVVNRLRGGLKVAAVKAPGFGDRRKAMLQDIAILTGGQAISEDLGIKLENVTLQMLGRAKKVMIDKENTTIVNGAGKKADIEARVAQIKAQIEETTSDYDREKLQERLAKLAGGVAVIRVGGATEVEVKERKDRVDDAMHATRAAVEEGIVPGGGVALLRASEQLKRIKTQNDDQKTGVEIVRKALSAPARQIAINAGEDGSVIVGKILEKEQYSYGFDSQTGDYGNLISKGIIDPTKVVRTAIQNAASVASLLITTEAMVAELPKKNSPAPAMPGGGMGGMDF", "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."}]}
+{"id": "function_test_1338", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNIYTSILVLSYLIGSIPFGLILSYIGGLGDIRKIGSGNIGATNVFRKSKKLAVVTLILDSLKGFVSVMLAKNFSSDQTFVFMSALFSIIGHMFPVWLSFKGGKGVATLLGSIMFIEYKFVIYFTIFWIIVFVIFRYSSLSSIISTISIMLLVYTHYSANESITFLVMSLLVIVQHIENIVRIIKGKENKI", "output": "Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP."}]}
+{"id": "function_test_1339", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRSVLKVFLENVIRDAVTYTEHARRKTVTAMDVVYALKRQGRTLYGFGG", "output": "Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling."}]}
+{"id": "function_test_1340", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEDPSKVQLNQLTDYIMKNCLWQFHSRKWDRERQNEGILTKTKQILLGEEVDLSTPADRCYYADALCLADAYKTEYPWINDMSKDELIQLMQQLKDRIDYVTITGSLNAELTDPRY", "output": "The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein (component 2) and a component 1 which is either a molybdenum-iron protein, a vanadium-iron, or an iron-iron protein."}]}
+{"id": "function_test_1341", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAKKLYIETHGCQMNEYDSSRMVDLLGEHQALEVTARAEDADVILLNTCSIRERAQDRVYSQLGRWRELKLANPEMVIAVGGCVASQEGAAIRDRAPYVDVVFGPQTLHRLPEMIDAARITRLPQVDVSFPEIEKFDHLPEPRVDGPSAYVSVMEGCSKYCTFCVVPYTRGEEVSRPFDDVLSEVIHLAENGVREVTLLGQNVNGYRGTTHDGRVADLADLIRVVAAVDGIDRIRYTTSHPLEFSDSLIQAHAEVPELVKHLHLPVQSGSDRILAAMKRNHTTLEYKSRLRKLRAAVPGISISSDFIVGFPGETEKDFDNTMKLIEDVGFDFSFSFVYSPRPGTPAADLKDDTPEALKKERLAALQHRLNQQGFEISRQMVGSIQRILVTDYSKKDPGELQGRTENNRIVNFRCNNPKLIGQFADVHIDDAQPHSLRGSLLQ", "output": "Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine."}]}
+{"id": "function_test_1342", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MISHEHPISIYWNDCSKSEQKKLLTRPINNKLNDIYINVKNILTKVYNEGDRALFKFNFDFDNVQTTQLQIPTEIIMNSGRNLSNEIKQAIHTAMTNITRFHQAQCYSEIIVETLPGVYCQQIIRPLNIVGLYVPGGTAPLLSTVMMLGVPARIAKCKRVILCSPPPIPDVIIYTAQLCGIDEIYQIGGSQSIAAMGFGTESIPKVDKIFGPGNIWVTEAKRQINLAPNGAAIDMLAGPSEILIIADNTANPIFIAADLLSQSEHGPDSHAILITPYSCIAEKTKKELHKQLKILPRNDIVRNVLLNSRMIITNNLMECFSISNSYAPEHLIIQIENASDYLHYITNAGSIFLGNWSPETAGDYASGPNHVLPTYGRAVATSGLGVIDFQKRMSVQQLTQNGLLQLSSTITTLTQIEQLKAHEYAITHRINYIKEQNEHSLLG", "output": "Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine."}]}
+{"id": "function_test_1343", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPKASASSAKMTASTSNVSSSNSKLKKSKASSPSASPEVSTPSTSNSNDDQDGHVSEDMSDAEEGESQEHSASGSGISDHDDDDDPSADKDSPAADEEQDEKKVATIADDGKKVEFSDLGVIPQIVEACTNMGFKHPTPIQVKAIPEALQARDVIGLAQTGSGKTAAFTIPILQALWDNPKPFFACVLAPTRELAYQISQQVEALGSTIGVRSATIVGGMDMMSQSIALSKRPHVIVATPGRLQDHLENTKGFSLRGLQYLVMDEADRLLDMDFGPIIDKLLQSIPRERRTMLFSATMTTKVAKLQRASLKNPVRVEVDTKYTTVSTLKQHYMFMPFAHKDTYLVHLANEQAGHSIIVFTRTVHDSQRLSILLRLLGFPAIPLHGQLSQQARLGALNKFKTGGRSILVATDVASRGLDIPAVDLVVNYDIPTNSKDYIHRVGRTARAGRSGRSVTLVTQYDVELLQRIEAVIGLKMTEFPGGNDKEAVMLLSERVAEAHRAAVRELKDKGVGSAGGSGKRKRKMDGKYGDDMDRDDDQVQAGLPVSGNGRHQNQNRKKGRR", "output": "ATP-dependent rRNA helicase required for pre-ribosomal RNA processing. Involved in the maturation of the 35S-pre-rRNA and to its cleavage to mature 18S rRNA."}]}
+{"id": "function_test_1344", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNTPKSDNYLSELRKVIWPIEKYENKKFLPMAFMMFCILLNYSTLRSIKDGFVVTDIGAEAISFLKTYIVLPSAVIAMVIYVKLCDILKQENVFYVITSFFLGYFALFAFVLYPYPDLVHPDPETIESLSLAYPNFKWFIRIVGKWSFASFYTMAELWGTMMLSLLFWQFANQITKTDEAKRFYSMFGLLANLALPVTSVIIGYFLHEKTQIVAEHLKFVPLFVIMITSSFLVILTYRWMNRNVLTDPRLYDPALVKEKKAKAKMSLIDSFKMIFTSKYVGYIALLLIAYGISVNLVEGVWKSKVKELYPTKEAYTIYMGKFQFYQGWVAIAFMLIGSNILRKVSWLAAAMITPLMMLITGAAFFAFIFFDSVIAMHLTGILASGPLALAVMIGMIQNVLSKGVKYSLFDATKNMAYIPLDKDLRVKGQAAVEVIGGRFGKSGGAIIQSTFFILFPAFGFVEATPYFASIFFVIVILWIYAVKGLNKEYQVLVNKTEK", "output": "Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism (By similarity)."}]}
+{"id": "function_test_1345", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSQLNPKVGFVSLGCPKALVDSERILTQLRVEGYDIVPSYDAADVVVVNTCGFIDSAVTESLDAIGEAMNANGKVIVTGCLGKRPEQIREAYPQVLAVSGPQDYQSVMEAVHAALPPRHDPFVDLVPDYGIKLTPRHYAYLKISEGCNHRCSFCIIPSMRGDLASRPVDEVLREAERLVRGGVKELLVVSQDTSAYGVDLKYAERPWRDRMYQTRMKALCEGLSELGVWTRLHYVYPYPHVDDVIPLMAEGKLLPYLDIPFQHASPRILKLMKRPGAVEKTLERVQRWKAMCPEITVRSTFIVGFPGETDAEFEALLEFLDQAQLDRVGAFAYSPVEGASANALPDPVPEELKQERLARFMARQAEISAARLEAKIGSVQQCLVDLIEDDIAVARSRADAPEIDGLVHIQNGGELKLKVGDLVDVEITDSDEHDLFGDALPSDPAAQPPRALNLQMV", "output": "Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12."}]}
+{"id": "function_test_1346", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKGLLQRVRSARVEVGTEVVGAIEQGILVLVGIEPQDTRASADKLLHKLLNYRVFSDVEGKMNLSLREVGGGLLLVSQFTLAADTKSGLRAGFSKAAPPALGAELFDYLLSQARIAHPTVAAGQFGADMQVHLINDGPVTFLFDT", "output": "An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality."}]}
+{"id": "function_test_1347", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQVHDNHRRPLVSLRISVTGRCNVSCIYCHRDGILRSDEEMSPEDIENICRVASDLGVKKIRLSGGEPLIRDDIVEIVEKINSIGFRDISITTNGTLLEDLSVPLRDAGLDRVNVSFDTLKPETYRFITRKDYLERVKAGIEGAVMAGLDPVKINMVILRGVNHHEIWDMFEFCRQQGAVLQIIELLKTDSCPDNGVERYHCDITPIEAELAEMADRIMTRKFMQDRKKYFIGDGEVEVVRPMDNTRFCANCTRLRVTPDGKLKPCLLRNDNLVDTKEALSSGDLEGLRELFLEAIRRRSPYYQS", "output": "Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate."}]}
+{"id": "function_test_1348", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSYNGIGLQSVRGSATSGHIQKNIANKISKPGHYESRKNQKSLMSKRADEAKQSQNKREAYKQIKSELTKHEQLRRIEVKCMDLQDELEEQGVEPDEIKARVDELRKKLNNKEFDENDAKSPTTTTPQPSRKDKQLKEDLENENKNKDGVFEYKRRYADKRN", "output": "Involved in pre-mRNA splicing. May function at or prior to the first catalytic step of splicing at the catalytic center of the spliceosome. May do so by stabilizing the catalytic center or the position of the RNA substrate (By similarity)."}]}
+{"id": "function_test_1349", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTIELLKSIVESETSIPPSSQRLVYNQQLLGDDSKTLEQVGIGEGDMLGVHVTLRGGAPSVQGQARPTGIGGTSGASHSQQIQQRRQQQINPDPEMIRLHILGDPRVRDAVRQRNPELADVAHDPHRFREVLLTQQRLESQREAEKEARIAMLNADPFNPENQKEIEEIIRQNAVTENLHNAMEHHPESFGRVTMLYIPVEVNGHKLNAFVDSGAQVTIMSPDCATACNIMRLVDSRYGGIAKGVGTANILGRVHSAQIKIGDMFLPCSFTVMEGKHIDLLLGLDMLRRHQACIDLRRGALVIQDQAVPFLGEADIPKHLLEEFEDEPVIKGADGAEVGARTGAVTHQAGGSTPAPGPSSAANATASSSRPAAVHRPSPRWPEASIAKITELGFTREEATRALEAANGDLDGAIGFLI", "output": "Probable aspartic protease. May be involved in the regulation of exocytosis. Acts as a linker between the 19S proteasome and polyubiquitinated proteins via UBA domain interactions with ubiquitin for their subsequent degradation. Required for S-phase checkpoint control."}]}
+{"id": "function_test_1350", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPLPSSQPSASSSPNLKRKQPTISSFFTKKPQAPKQSTSNEGPAPIDNDSEITDKLAEDDEEDIVAPVPKRTKSNGSLTVNRPQSPKAKSVSRVEQESSQRTELSKFASSPAIETEGNEATELDGSAKVRQQEREKLHQRFVRKLGGPDCLVGIGRNCVGETTSIEEAAEGDEDDETPQPVQPKGKAGKKGGGKLTPMEKQVIEIKKKHMDTILLIEVGYKFRFFGEDARIAAKELSIVCIPGKFRYDEHPSEAHLDRFASASIPVQRLHVHVKRLVAAGHKVGVVRQLETAALKAAGDNRNAPFVRKLTNVYTKSTYIDDIESLEGSTAGASGASATGYILCITETNARGWGNDEKVHVGIVAVQPTTGDIVYDEFDDGFMRSEIETRLLHIAPCEMLIVGELSKATEKLVQHLSGSKMNVFGDKVRVERAPKAKTAAAESHSHVSSFYAEKMKSADAADDEVASNLLQKVLGLPDQVTICLSAMIKHMTEYGLEHVLQLTKYFQHFSSRSHMLLNGNTLTSLEIYQNQTDYSSKGSLFWTLDRTQTRFGQRMLRKWVGRPLLDRRQLEDRVNAVEELKDFRNVVMVERIKGLLGKIKHDLEKGLIRIYYGKCSRPELLTILQTMQMIAQEFADIESPADTGFSSPAISQAIMSLPTILKDVVFFLNKINMHAARNDDKYEFFREEEETEEISEHKLGIGAVEHELEEHRPVAGEALGKKMVTYVSVAGIDYLVEVENNSPAIKRVPASWMKISGTKKVSRFHTPEVVKMIRQRDQHREALAAACDKAFLALQAEIATNYQALRDCVQSLATLDCLVSLATLASQPGYVKPEYTEETCIHVEQGRHPMVEQLLLDSYVPNDINLDSSKTRALLVTGPNMGGKSSYVRQVALIAIMGQIGSYVPAQAAKLGMLDAVFTRMGAFDNMLAGESTFMVELSETADILKQATPRSLVILDELGRGTSTHDGVAIAQAVLDYMVRSIRSLTLFITHYQHLSAMVHSFPDGELRNVHMRFSESGTGADEDITFLYEIGEGVAHRSYGLNVARLANLPAPLLEMAKQKSAELEEKIRRRRLAGFVAAVGAVVQSNQADESVIERLVSSMEEL", "output": "Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with msh2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. Msh3 provides substrate-binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions (By similarity)."}]}
+{"id": "function_test_1351", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAFCGPRTAARLSHSTRALHYTHRGHVSQRTLNEVVIASAARTPIGSFQGSLSSLPATKLGSIAIKAAVERAGIPGDEVKEVYMGNVLQAGQGQAPSRQATLGAGLAISTPTTTINKVCASGMKSIMLAAQSLMCGHQQVMVAGGMESMSNVPYCMSRGATPYGGVKLEDIIVKDGLTDVYNKFHMGNCAENTAKKLSISREEQDSFAINSYTRSKAAWDSGLIANEIVSVTISQKGRPDIIVQEDEEYKRVDFSKFSKLKTVFQKDNGTVTAANASTLNDGAAALVLMTAGAASRLNVTPLARIVAFADAAVDPIDFPIAPAYAVPKLLSEAGLKKEDIAMWEINEAFSVVVLANVKMLDIDPARVNVNGGAVSLGHPIGMSGARIVGHMAHVLKKGQFGIAGICNGGGGASAVLIEKL", "output": "This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism."}]}
+{"id": "function_test_1352", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDKNLLEAVKFDEKGLVCAIAQDAETKRVLMVAWMNAEALQKTVETGFAHYYSRSRQKQWMKGEESGHTQKVRELRLDCDGDTIVMLIAQNGGIACHTGRESCFYKKWNGGAWETADAVLKDEKEIYGSTH", "output": "Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP."}]}
+{"id": "function_test_1353", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKVTIAHNNYDKTLKTVAYLKEILKKKNVVFDAKYPDVVISVGGDGTLINAFHRYENQVDSVRFIGVHTGHLGFYTDWRNYDIDKMVDALLLTDEAPAKYPLLEIKLITESGETKYHLAVNESAVKRVSHTLEADVYINDELFENFRGDGLCVSTPTGSTAYSKSLGGAVIHPRLKALQMTEIASINNRVFRTLSAPIVIAPDQWITIVPNADHFVMTVDGARIDVRNAKKIEYRISHHSIQFDQFGHHHFWSRVQDAFIGENNSND", "output": "Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP."}]}
+{"id": "function_test_1354", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSEASGERPRVEIWTDGGCKPNPGPGGWGALLVCRGQEKELLGGDPETTNNRMELTAAAEALEALKRPCIVTLHTDSEYLRNGITRWHTGWVRRKWRNAAGDPVANMDLWQRILEAAKPHEIDWLWVKGHSGDENNERVDQLATRGREEL", "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."}]}
+{"id": "function_test_1355", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTHYHFVGIKGSGMSSLAQIMHDLGHEVQGSDIESYVFTEVALRNKGIKILPFDANNITKEMVVIQGNAFPDNHEEIVRAHELKLDIIKYHDFLGHVINQYTSVAVTGAHGKTSTTGLLSHVMNGDKKTSFLIGDGTGMGLPGSDYFAFEACEYRRHFLSYHPDYAIMTNIDFDHPDYFKNIDDVYDAFQHMALNVKKGIIAWGDDEYLRKLDVDIPVYYYGFKETDDIYAKNIQITEKGTQFDVYIKGEFYDQFLSPQYGNHNILNALAVIAISYLEDMNVENIKEALITFGGVKRRFNETKVSNQVIVDDYAHHPREISATIETARKKYPQKDVVAVFQPHTFSRTQAFLNEFAESLSKADQVFLCEIFGSIRENTGDLTIEDLINRIDGSTLIDENSIDVLEKFDNAVILFMGAGDIQKLLKAYFEKLGVKNDF", "output": "Cell wall formation."}]}
+{"id": "function_test_1356", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEVKAKQLDSVNATASVKIPSGMIKSEVENLAKKASKSVKMDGFRPGKVPVSAVLKRYERELTQDAEQNLFKSAVNSALQELKKENKELVGEPYFEKFDRKDGEIIAELILSFKPEIKLEGYEKLIPEYQTPKVSKKEIDEKKDELLKRFATPEAIKTKRALKEGDFAKFDFEGFVDDKAFEGGKAENYVLEIGSKQFIPGFEDGMVGMKIGEEKDIKVTFPKEYGAAHLAGKDAVFKVKLHEIQELKIPELDDEMLKKLLPGEEKASVEVLDEKLKEQIKNEKLFKLVNDELKGKFADALIEKYNFDLPKGIVEQETDMQMRAAFNTFSEKEIEELKASKEKYQEKRDSFKEEAQKSVKLTFIIDELAKLRKIEVNDQELIQAIYFEAYRYGMNPKEHLENYKKQGALPAVKMALIEEKLFNDIFIPKTEKSEKVSKKEKEDK", "output": "Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase."}]}
+{"id": "function_test_1357", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKKIFVKPRELVVPGTLLAQGPFKNGRGTFREGNAIYSTVIGLVEIRGNVIRVIPLEGPYIPEVGDNVLGKIVDVKFSSWTVDIGAPYQASLRVQDAVEERIDLLKTDLRKIFDIGDIIYAKVKAFNEVNQIDLTTKGMPFKGGPLRGGQLVTITPSKVPRLIGKGGSMINMIKTLTGTRIIVGQNGWVWVSGKNDELERLAIEAILKVDRESHTQGLTDRVKEFLLSRLRELKEQGVIEEIPEVNGEEGGEDDGQA", "output": "Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome."}]}
+{"id": "function_test_1358", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTHLHAGLNPETIEKGRLELNENPDTLHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFNQMEAFRLLAQYFQYRQLNLDMFKNLKADDPGIKRALMDGFPGVLENRDHYGRKILLLFAANWDQSRNSFVDILRAILLSLEVLIEDQELQINGFILIIDWSNFSFKQASKLTPSILRLAIEGLQDSFPARFGGVHFVNQPWYIHALYTIIKPFLKDKTRKRIFLHGNNLNSLHQLIHPDCLPSEFGGTLPPYDMGTWARTLLGPDYNDENEYTHSSYNVIHVKHVPAIVEGEDSPKYMKRSHSVVEPGTLRHEEERENENTQPLLALD", "output": "Required for normal morphology of late endosomes and/or lysosomes in neurons. Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (By similarity)."}]}
+{"id": "function_test_1359", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQEIQKNTKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMVCLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHILPAYLEQLGVEYKIVEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFLNMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIIRFAEAKAFPIIPCNLCGSQPNLQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVVDGGDLAFDREEIPLQPAGWQPEEDDTSLEALRLDVIEVK", "output": "Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system."}]}
+{"id": "function_test_1360", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDVYLVGGAVRDKLLKLPVHERDWVVVGARAEDLLKQGFLQVGKDFPVFLHPSTREEYALARTERKSGKGHTSFDVFASPDVTLEDDLARRDLTINAIAQSEDGEIVDPYNGVQDIKARKLRHVSEAFTEDPLRVLRVARFAARFAHLDFTVAEETQQMLQEMSASQELSHLVPERVWREWEKSLLTQTPTVFLTLLRDIQALSQVLPGITADDSQLQRLQRTSAYSDSVTLRFASLFIEQETPESLKQFCRQLAIPNHYRDSALLARNHEDFITTPELPEKAQLAALLKQIDYWRRPEKLEQLLQLRQAEYSESKQQKSIAAQHKKLRSGAEKAAALNAGTLQQQGFTGKALGDALREQREQILAEALN", "output": "Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate."}]}
+{"id": "function_test_1361", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGSRNSSSAGSGSGDPSEGLTRRGAGLRRSEEEEEEDEDVDLAQVLAYLLRRGQVRLVQGGGAANLQFIQALLDSEEENDRAWDGRLGDRYNPPVDATPDTRELECNEIKTQVELATGQLGLRRAAQKHSFPRMLHQRERGLCHRGSFSLGEQSRVISHFLPNDLGFTDSYSQKAFCGIYSKDGQIFMSACQDQTIRLYDCRYGRFRKFKSIKARDVGWSVLDVAFTPDGSHFLYSSWSDYIHICNIYGEGDTHTALDLRPDERRFAVFSIAVSSDGREVLGGANDGCLYVFDREQNRRTLQIESHEDDVNAVAFADISSQILFSGGDDAICKVWDRRTMREDDPKPVGALAGHQDGITFIDSKGDARYLISNSKDQTIKLWDIRRFSSREGMEASRQAATQQNWDYRWQQVPKKAWRKLKLPGDSSLMTYRGHGVLHTLIRCRFSPIHSTGQQFIYSGCSTGKVVVYDLLSGHIVKKLTNHKACVRDVSWHPFEEKIVSSSWDGNLRLWQYRQAEYFQDDMPESEECASAPAPVPRSSTPFSSPQ", "output": "May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex."}]}
+{"id": "function_test_1362", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MFVDIHTSSKQYKAEVGSGILREAGKTIEALAPASSYLIVSDENVANRYLDVLVSSFSKEPHTFVVKAGEQSKSFHVYEQLAAFCLEKQLDRQSVIIAFGGGVVGDLAGFVAGTYMRGVRFIQVPTTLLAHDSSVGGKVAVNLPAAKNMIGVFHQPEAVLFDTELLATLPEHEWRSGFAEIVKLGFIADASFLAWLRETVPALTSIKADNLQKMVAKAIAIKADIVGKDEKEHGIRAHLNFGHTLAHAIEAELGYGKITHGEAVAIGMRFAFRLSLRFTKEDLRLADYEEWFSALGYDLRLPAGLSAQRLLARMKSDKKTNAGKIVMVLLAQLGAAYTKTVDEHLLLELLEEELGGRS", "output": "Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)."}]}
+{"id": "function_test_1363", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFLTLIAAIISFMVSAFTMPYFIKFYQLKKIGGQQMHEDVKQHLAKAGTPTMGGTVFLLVATAVSLLVSLFSIKNTQSLALISGILSIVVIYGIIGFLDDFLKIFKQINEGLTAKQKLALQLAGGLMFYFLHVSPSGISSINVFGYQLSLGIFYLFFVLFWVVGFSNAVNLTDGIDGLASISVVISLVTYGVIAYVQGQFDVLLLIGTMIGALLGFFLFNHKPAKVFMGDVGSLALGAMLAAISIALRQEWTLLIIGIVYVLETSSVMLQVSYFKYTKKKYGEGRRIFRMTPFHHHLELGGLSGKGKKWSEWQVDAFLWGVGSLASLLVLAILYVF", "output": "Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I."}]}
+{"id": "function_test_1364", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTIMRKSHPLMKIVNHAFIDLPTPPNISGWWNFGSLLGLCLILQILTGLFLAMHYTSDTLTAFSSVTHICRDVNYGWLIRHMHANGASLFFICLYIHIGRGIYYGSYLYTETWNIGILLLLLTMATAFVGYVLPWGQMFFWGATVITNLLSAIPYIGQDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPLGIPSDCGKVPFHPYYTTKDFLGAIMLLMLFLTLVLFFPDKLGDPDNYMPANSLNTPPHIKPEWYFLFAYAILRSIPNKLGGVVALALSILVLALLPYLHTSKQRSLSFRPLSQTLFWMLVADLLLLTWIGGQPVEPPFIIIGQVASALYFLILLLLMPMAGLIENKLLKW", "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."}]}
+{"id": "function_test_1365", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNVPHSVKSRADAYWRLMRFDKPIGIFLLLWPALWALWIAGEGRPDPGVAAVIVFGVVLMRAAGCVINDYADREFDPHVERTRLRPIAAGEVTSKEALILFMVLCLTAFALVLTMNWLTIALSVPGAFLAASYPFTKRYTHLPQAYLGLAFGWAIPMTFAAQTGSIPVVAWALYAATVLWALIYDTMYAMVDREDDVKIGIKSTAILFGKYDREIIGALQIAMLAILAGIGRYLGLGGLYALGLAAAAGFSVYQQVLIFRREKSKCFRAFLNNHWFGAAVFAGLFADYLWAG", "output": "Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate."}]}
+{"id": "function_test_1366", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MYKLCAVLFALAVPAVRPHGYLSTPVARQYKCFADGNFYWPDNGDGVPDEACRNAYKKVFHRYRAVGAPPGEAAAAAQYMFQQYAEYAAVAGPNYRDLELVKREVLPHTLCGAAANDRHALFGDKSGMDEPFHNWRPDVLYVNRYQRAHSFNVHFCPTAVHEPSYFEVYVTKFTWDRRSPVTWNELEYIGGNGSGLVPNPGDAFCASGQLYSIPVSVPYRPGPFVMYVRWQRIDPVGEGFYNCADLVFGTENDECRYARAAKAVRDQLRQQNLCNDCVEAGPQESCAPTRPQRRAHNYLRRGGAHDQQADGASVRETIDEL", "output": "Component of the virus occlusion bodies, which are large proteinaceous structures (polyhedra), that protect the virus from the outside environment for extended periods until they are ingested by insect larvae."}]}
+{"id": "function_test_1367", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIFLPVTSVVFAISWIYSGVSAFNPYSSTPYSLKYVDEQEFLSVIDNETLLQEGRLFRPYEGSDVLCYQRNTSSLIQHHEEDTFNSEGALIEAVNMVNAILAPNPIEMNTVPISYWTYIISSGETRTVVQKGYFGETYLLGNSSNYNSTIDYHFAKSKTGRVYLSETLVDGCTCDLTHKPREVEIQYICPKRPLSRPFHLEVREIQSCKYQLRLFLPQLCELSSFNPLLGQLSEHNIICHRSGSKLSPALDIFNRYSATVLDHGIYLLKPKNSAKDRRQLMYHAAEPLDSQTTLFELTVEERFIGDFISSLKKLIGSDFIQSPTGKSIKPGDLFLWRAPVVDETGNLLFLIDLELNSASEAIGKVNNDASLLNELPIHNMVYFDSMTVNQTDETSSNSLPEKSTGLVPDIFATDEIESPYKGGTAQELKDKLMEAFRDIGYPDIEVEILEEVVEEQN", "output": "Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation (By similarity)."}]}
+{"id": "function_test_1368", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTTLESLKIEDIPVDDIDFSDLEREFQIQDGGVNFDNFLVVDGAPVAPEAKVPVLEKVLTKLFSQAGKVLDMQIPVEDGKTKGHLFIEMESVSAAKEAIQLFNGKKLDAKHRLLVNSLNDMEKYGSDDFESQSHEPVVPDFAPTDFLRSWLQNQDGRDQFVLQKGDMTRVFWNRLAHQPDGVGEARKNWSNDVVKFSPKGTYLLSFHDQGVTSWGGPNFDRLKRFFHPDVSRLDVSPTEKFLITFSMNPIKPGEDTPFGPESEGHQICVWDLATGFLMKTFGIPPNAKLQWPLIRFSYDDKYCGRLGPNALAIYDIENNFQLLDGKLHKVEGIQDFSFAPKGVQLTYNRRKSDPTTLLAYWTPETNNQSCKAFLMTLPNKRIVKTVNLVQVSNVSIHWHEQADFVCFQVDRHTKSKKTFFTNLEICKLNESEIPVEKIEMKDRVLELAWEPKGTRFVTISKMDNGGEENPMYPKNFVKFFAPEKKDNKDKDLAVLPDQLKWKLVKTVDQQFANCISWSPAGRFVAVCTIVNGKEIKKASLDFYDFDFTGEKTLNEVQDVKASLQAVAHIDNQFFTDLEWDSSGRFLTAWSSYSKHKLENGYTIYNCCGEAVRKEIVDQFRNFVWRPRPESLLSNAEKKKARKNLKQWSVKFEEQDAMESDSALRDLILKRRAELSAWVSYREQSKERLESEDSYTIFDNFESDKADETQYVTVEEVKEEILEETQEEVESFE", "output": "RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation."}]}
+{"id": "function_test_1369", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEAAEGSENYDGIQVLLSREVIDTAPQCPHGPTLLFVKVSQGKEQGRRFYACSACRDRKDCHFFQWEDEKVSQARLAAREEYNKSHQPPMTHAEYARSFQEFTALPLAKRKFCCDCQQLLLQTNWETHSRHRVLGDISLSQLKRPSQLLHPLENKKANAQYLFADRSCTFLLDTIIALGFRRVLCVGTPRLHELIKLRACKGTTPPIKSLLLDIDFRYSQFYSEEEFSHYNMFNHHFFGGEAAKLVCQKFLQEEDGNGALLVTDPPFGGLVEPLAFSFKRLREMWKDSNPENANNLPIFWMFPYFFESRILQCFPDFAMLDYQVDYDNHALYKHGKTGRKQSPVRIFTDLPLDKIVLPASEGYRFCSVCERFVCSENKHCDICNRCTSKDGRSWKHCSQCKKCVKPSWSHCSACNHCALPGHPCGTAGDGCFLCGGKGHKRRGCPHLSVSADGERMKRNLKQRSIKGNMKKQPTATTSKKKKRKRNNPC", "output": "rRNA N6-methyltransferase that specifically methylates the adenine in position 4220 of 28S rRNA. N6-methylation of adenine(4220) in 28S rRNA is required for translation."}]}
+{"id": "function_test_1370", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD", "output": "Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules (By similarity). Its phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity)."}]}
+{"id": "function_test_1371", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEMEEFAPSYYYYVEPEMGYQPQQPNPMEDLITVYHLDDISRQVARTNEDGTKAVKLRKSYKNQITDLSGKFSSIPNRENRKGGEIAHILFQNNPDMMNQVHRSPDMTDEQWREALMNVDASLFQAPNMDWEVCQSVLSQFDRSYPTEFQNDPNFHVDDLAFDLDGTGKSNAKKRKNRSNGSSMATPNSEMQDDVKRRRLE", "output": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity)."}]}
+{"id": "function_test_1372", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRLLGIETSCDETAAAVIEHNIEGNSQILSNIVWSQTDNHAPYGGVVPEIAARAHVEILDDLILKALTDAHTKLKDIDAIAVTSGPGLIGGLLVGVMSAKALSLATGKPFIAVNHLEGHALTAVLTHNVAFPYLLLLVSGGHTQTILVHEVGNYQRLGTTIDDALGEAFDKTAKLLGLPYPGGPALEKAALLGDKNRISLPRPLKGEKRLDFSFSGLKTAVRQAATAMSPLTENDVADIAASFQAAVTDTVYDRVHLALQYFTHQYPLSHYKGRRPPALVVAGGVAANQAIRLTLQELAHQHGFEFIAPPLSLCTDNAAMIAFAGAQKFARGEKNSFDIAPRSRWPLDEKAAPLIGTGRRGTKA", "output": "Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction."}]}
+{"id": "function_test_1373", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKERFLVTGGARLEGTVHVSGAKNSVLKLMAAALLAEGTTTLTNCPKILDVPYMVRVLEGLGCSVVHSGSTVEITTPAEISSNADFDAVRQFRASVCVLGPLTSRCGKAVVALPGGDAIGSRPLDMHQSGLEKLGAKTHIEHGAVVAQADQLRGANIHLDFPSVGATENILTAAVLAEGTTVLDNAAREPEILDLCVMLKEMGADIEGEGTSTITIRGVEKLHPTQHEVIGDRIVAGTWAYAAAMTQGDITVGGIAPRNLHLALEKLKVAGAEVTTYDHGFRVRMDRRPMAVDYQTLPFPGFPTDLQPMAIGISTVADGVSVITENIFEARFRFVDELVRLGADATVDGHHVVMRGVEKLSSTPVWSSDIRAGAGLVLAALCADGVTEVNDVFHIDRGYPNFVEDLQRLGAQIERVQV", "output": "Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine."}]}
+{"id": "function_test_1374", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNFKYSILFICFVKVLDNCYAADDLTTLRNGTLDRGITPDCTFNEKDIELHVYSRDKRNGIILKKEILKNYDLFQKSQISHQIAILIHGFLSTGNNENFDAMAKALIEIDNFLVISVDWKKGACNAFASTNDVLGYSQAVGNTRHVGKYVADFTKLLVEQYKVPMSNIRLIGHSLGAHTSGFAGKEVQRLKLGKYKEIIGLDPAGPSFLTNKCPNRLCETDAEYVQAIHTSAILGVYYNVGSVDFYVNYGKSQPGCSEPSCSHTKAVKYLTECIKRECCLIGTPWKSYFSTPKPISQCKRDTCVCVGLNAQSYPAKGSFYVPVDKDAPYCHNEGIKL", "output": "Catalyzes the hydrolysis of phosphatidylcholine with phospholipase A1 activity (By similarity). May act as an allergen and induce hemolytic activity (By similarity)."}]}
+{"id": "function_test_1375", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MHSLFTLNLDLERAGKVICAQSLPFDTARETLLLLSPVGTQCCYMKNAALFLISHFNLIILESDTWLAYANEAGVNPEEGVADFIRQFNAALPEPVRVDALVGYCSSAPLALLAANQGACRTLLLLNGAYFLKDDGVIKSQYERDVERMMQSIPQGNCAQVYEAVSLLHTQSTYTPSDYRYQQVRPLRELSAFRQYLTFLNNLASLELVRIAQAVKTPTLVWCGSQDRYTDTASSRYIAQLLPHSELVEDPDGQHHDFVDGHERLYLTMTRFLTRHKQRAIQ", "output": "Involved in the biosynthesis of the phytotoxin coronatine (COR). Catalyzes the transfer of the aminoacyl group covalently attached to the pantetheinyl arm of CmaA to the holo-pantetheinyl arm of CmaD. During the shuttling process, CmaE generates a covalent-aminoacyl-S-Cys enzyme intermediate by the action of its donor substrate L-aminoacyl-S-CmaA and delivers it to the sulfhydryl group attached to the phosphopantetheinyl arm on CmaD."}]}
+{"id": "function_test_1376", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDRAVKLYRKLKREITFHGAKEIALGYSAGALASCMGLIYNRMGAVTTEVAFGLVCATCEQIADSQHRSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSEQAAEAMEVASQARQMVQAMRAIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK", "output": "Plays critical roles in virus replication, from virus entry and uncoating to assembly and budding of the virus particle. M1 binding to ribonucleocapsids (RNPs) in nucleus seems to inhibit viral transcription. Interaction of viral NEP with M1-RNP is thought to promote nuclear export of the complex, which is targeted to the virion assembly site at the apical plasma membrane in polarized epithelial cells. Interactions with NA and HA may bring M1, a non-raft-associated protein, into lipid rafts. Forms a continuous shell on the inner side of the lipid bilayer in virion, where it binds the RNP. During virus entry into cell, the M2 ion channel acidifies the internal virion core, inducing M1 dissociation from the RNP. M1-free RNPs are transported to the nucleus, where viral transcription and replication can take place.; "}]}
+{"id": "function_test_1377", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKFNIAKKGGVVAQLVFEEKIEGGYLNHLKEKELFSGKAEDVYYTLDSNLKAQLFIGLGKEEKIDLEVLRKTFFKAASELLKNKVEEVELNIPKLNNLCNYKTAEAIAEGMLHATYKYDKFKSDRKEQTEITVNYNPEKGKEDRAEKGINEAVKLMEAVFLTRDLVNQPANVIYPETLAKIAKEKLEAKGVKVTVHGKKEIEALKMEAFLNVARASTKEPKLIVMEYYNNPGSNEKIALVGKGLTYDSGGYAIKPATSMVDMFTDMGGSGTVIGAMHALADLKAKVNVVAVVASCENMISGDGYRNGDIIGSMSGKTIEIINTDAEGRLTLADAVYYATNNLGATKLIDLATLTGACVSALGEQVSGAVTNNDEFFSELVKANERAGEIVWRMPTIEYYKKMNESKVADLKNSGGKLGGMMTAGLFVGSFLAKEDIPWIHIDIAGTAYITEKFGYLKENATGTLVKSLYYMLSKEA", "output": "Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides."}]}
+{"id": "function_test_1378", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVSLSSHPARALRGEIAVPGDKSISHRSIMLGSIARGVTTVSGFLRGEDNIATLDAFRAMGVQVHDDGETLRIEGKGLHGLTEAEDVIDCGNSGTSIRLLTGLMAAQRFYTVLTGDRYLRRRPMRRVVEPLSRMGACIHGRDNGEKAPLAIVGRPLTGIAYDSPVASAQVKSALMLAGLYADGATRVTEPHLSRDHSERMFRHFGARLETDAAGVTVYGGHELDGRDIVVPGDISSAAFFLVAALIVPGSELLIRGVGVNPTRTGILDILAAMGGSVELLDQREVSGEPVADLLVRSSALKGIEIGGDVVPRAIDEFPVICVAAALAEGTTVIRDARELRVKETDRIAAMAANLRAAGATITETADGMIIEGTGRLNGVTVESFGDHRIAMSMLVAGLAASGAITVSDTECIATSFPTFTALLDKVAVR", "output": "Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate."}]}
+{"id": "function_test_1379", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNIHEYQAKEILSAYGIPVPRGRVALTSDQVERAAKEMGGRCVIKAQIYAGGRGKAGGVKLVHHPEQAQDYGKELFGRRLITPQTGPEGLKVRRILVEEAVEIAREFYLSITLDRSTSRYCLIASAEGGVDIEEVVQKSPDKIHVLTIDPYTGLRPFQARRIALALGLSGTLCEDCVELMLNLYKVVLEKDCSLVEINPLVVTRAGWLMAMDAKINFDDNAIFRHREYPDMMDYSQLDTLEINAGKYDLSYIKLSGNIGCMVNGAGLAMATLDVLKEFGGEPANFLDVGGGATREKVAEAFKIILEDADVKGVFVNIFGGIMRCDVIAQGIIEAASEVHCTLPIVVRMDGSKVAEGKQLLVESGLNVQTADSLGEGAERIVGMLG", "output": "Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit."}]}
+{"id": "function_test_1380", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGVDQPLGDNFITTSLDSLVNWARKSSIWPMTFGLACCAIEMMATGASHNDLDRFGIIFRASPRQSDCIIIAGTVTKKMLPVIKTVYEQMPEPKWVVAMGACACSGGVFDTYSVVQGIDTALPVDVYIPGCPPRPEALLYGLLKLQDKIMKDKNSFGSTIGLGERLESAA", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_1381", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEFFTMCMLAAGFGMAIGAFGTGIGQGLAVKNAVEGVSRNPGASGKILTTMMIGLAMIESLAIYVLVVCLIILFANPYKDVAIELAKAVVK", "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "}]}
+{"id": "function_test_1382", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSEMTPREIVHELNRHIIGQDNAKRSVAIALRNRWRRMQLEESLRVEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVESIIRDLTDVAVKLTHQQAMEKVKFRAEELAEERILDALLPPPRDAWGQNEQSEDTSNTRQIFRKKLREGKLDDKEIEINVAAPQMGVEIMAPPGMEEMTNQLQGMFQSLAGNTSKKRKLKIKDAFKALIEEEAAKLVNQDELKEQAIYSVENNGIVFIDEIDKICKRGESSGPDVSREGVQRDLLPLIEGSTVSTKHGMVKTDHILFIASGAFQVAKPSDLIPELQGRLPIRVELEALSSHDFKRILTEPRASLTEQYVALMKTEDVDIEFTEDGITQIAEAAWTVNETTENIGARRLHTVMERLMDEISFDATEKSGTKFVIDAAYVQQRLGEFVEDEDLSRFIL", "output": "ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis."}]}
+{"id": "function_test_1383", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIRQRTLKEIVKTTGVGLHSGRKVTLTLRPAAANTGIIYRRTDLTPAVDFPADPASVRDTMLCTALVNDEGVRISTVEHLNAALAGMGIDNIIIEVDAPEIPIMDGSASPFVYLLQQAGIETQNAAKRFIRIKKPVRFEDGDKWAEFVPFNGFRMDFEIEFNHPAIDSDEQRLLFDFSTQGFVREISRARTFGFMRDIEYLQSQNLVLGGSFDNAIVLDDYRILNEEGLRFENEFVTHKVLDAIGDLYMCGHAIIGEFRAYKSGHGLNNQLLRAVLADQEAWEWTTFEEEVGSPVAFAEPNMVLA", "output": "Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis."}]}
+{"id": "function_test_1384", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTNSNLRTENHFDYVKITLASPERVMEWGQRTLPNGQVVGEVTKPETINYRTLKPEMDGLFCEKIFGPSKDWECHCGKYKRVRHRGIVCERCGVEVTESRVRRHRMGFIKLAAPVSHVWYLKGIPSYVAILLDMPLRDVEQIVYFNCYVVLDPGDHKELKYKQLLTEDEWLEIEDEIYAEESEIENEPVVGIGAEALKQLLEDLNLEEVAEQLREEINGSKGQKRAKLIKRLRVIDNFVATSARPEWMVLDVIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLARLQEILAPEIIVRNEKRMLQEAVDALIDNGRRGRTVVGANNRPLKSLSDIIEGKQGRFRQNLLGKRVDYSGRSVIVVGPKLKMHQCGLPKEMAIELFQPFVIHRLIRQNIVNNIKAAKKLIQRADDEVMQVLQEVIDGHPIMLNRAPTLHRLGIQAFEPKLVDGRAIQLHPLVCPAFNADFDGDQMAVHVPLAIEAQTEARMLMLASNNILSPATGEPIVTPSQDMVLGSYYLTALQPGAEQPEFGDRSRTYSSLEDVIHAFEDTRIGLHDWVWVRFNGEVEDNDELDEPIKSETLSDGTRIEQWTYRRDRFDEDGALISRYILTTTGRVVMNHTIIGAVAAA", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_1385", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNESSEANDLAIRRQIIDETKCVVVKVGTRVLTTSDGKLDLERVDRLAEQLCRIADTGRQTIMVSSGAVGAGVAKLGLPQRPTDLKSLQAIAAIGQADLIGAYEKSLQKRGRHAAQVLLTRNDLRRRSGYLHVRNALNGIDELGAIAVVNENDSVAVSELKTTFGDNDRLAAQVAGLFNDVMLILLTDVSALYDGHPDEKDSQPIHMVHDVDDGVMALVDDQVSTVSKGGMGGKLRASKLANSHGHPTIIGSGTEEFVLDRIFAGDAVGTLFVPPKRSLKGRRRWIGSSANVAGTLFLDQGAVDAIQKHGRSLLAIGIQRVEGTFAHGNVVRLVGPNGEEFGRGLSNYRSHEVARIAGKPSEQIEWILGHRPYENVIHRNNLVLRIVPE", "output": "Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate."}]}
+{"id": "function_test_1386", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIMRTSWVASRKGQSNVSQMYFARREVITEEMSFVAKKENLPESLIMEEVARGRMIIPANINHLNLEPMAIGIASSCKVNANIGASPNASDVNEELKKLHLAVKYGADTVMDLSTGGVNLDEVRTAIIQASPVPIGTVPVYQALESVHGSIEKLSEEDFLHIIEKHCQQGVDYQTIHAGLLIEHLPKVKGRLTGIVSRGGGILAQWMLYHHKQNPLFTRFDDICEIFKRYDCSFSLGDSLRPGCLHDASDEAQLAELKTLGELTQRAWKHDVQVMVEGPGHVPMDQIEFNVRKQMEDCLEAPFYVLGPLVTDIAPGYDHITSAIGAAMAGWYGTAMLCYVTPKEHLGLPNPEDVREGLIAYKIAAHAADIARHRSGARDRDDELSRARYAFDWNKQFELSLDPERAREYHDETLPADIYKQAEFCSMCGPKHCPMQTKITDKDLENLESILSSKGAKEINTMKLDKEV", "output": "Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction."}]}
+{"id": "function_test_1387", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIEADRIISASPQREEEVVDRAIRPKLLTDYVGQPSVREQMEIFIKAAKLRHEALDHLLIFGPPGLGKTTLANIVANEMGVNIRTTSGPVLEKAGDLAAMLTNLEPYDILFIDEIHRLSPAIEEVLYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGATTRAGSLTSPLRDRFGIVQRLEFYNVDDLTSIVKRSAACLNLNLSADGAYEVARRSRGTPRIANRLLRRVRDYADVRNNGVITSEIAKQALVMLDVDPQGFDFMDIKLLQAIVERFDGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRIATTRTYAHLGISLSE", "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA."}]}
+{"id": "function_test_1388", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPSRVLITSALPYANGPLHFGHIAGAYLPADVYARFRRLLGDDVLYICGSDEYGIAITLNAERVGLGYQEYVSMYHKVHKDTFDKLGISLDFFSRTTNPFHKAIVEDFYLELKSKGLVENQISFQLYSEDEKRFLADRYVEGTCPKCGFDGARGDECQKCGADYEATDLINPRSKLSGSQLVLKETEHAYFHLERMVEPLLAFIEKAYLPEHIRKFVVDYIKNLRPRAITRDLSWGIPVPDFPNKVFYVWFDAPIGYISATMDWAASVNTPDLWKDFWLEESTEYVQFIGKDNIPFHAAIFPAMELGQSIPYKKMNALISSEFYLLEGAQFSKSEGNFVDMDAFLDTYSLDKLRYVLAATAPETSDSEFTFLDFKTRCNSELVGKFGNFINRVLAFAEKNGFRELTCPEALEDKDRQFLDDCQRIVQEAQAYYSKYSLRKACSAIMELAALGNVYFNDQAPWKLLKEGFAHRVEAILFCACYCQKLLALIAYPILPGTAWEIWNMLAPKSLDLENQDKDRVKNLWNTEFIDFSDEVFSLTTPQLLFTIVD", "output": "Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation."}]}
+{"id": "function_test_1389", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSLGPLMLDIAGTELTETDRVRLSHPLVGGVILFARNYASPAQLAGLTAEIHALRYPSLLIAVDQEGGRVQRFRDGFARLPPMRVLGEICDRNPDRAHHLASQAGYVLAAELKACGVDLSFTPVLDLDYGQSCVIGDRAFHREPQVVADLACALMNGLQSAGMAAVGKHFPGHGAIRADTHVETAIDTRSYTDIEKEDLIPFRRMIDAGLSGIMAAHVIYPAIDQHSAGFSSRWLQRILRHDLGFEGCIFSDDLGMQAARNYGSITRRAEQALQAGCDMVLVCNDADAADELLGSLHWEFSAASLARVECMRGQHMIHSMAQLHEMERFLQAADEISKIDPAGISVSL", "output": "Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides."}]}
+{"id": "function_test_1390", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MISENTIEERLQALRAAIALHDFHYYVQDAPVIPDAEYDALFRTLQQLEQQYPHLVTPDSPTQRVGAPPLKVFAQLTHQTPMLSLANAFSEEEVTAFDRRIREALNIDRVDYAVEPKFDGLAISLIYANGILTKGATRGDGYTGEDITLNLRTIPSIPLRLQVPFPTGQFEVRGEVVMLKTDFERLNEQQRKNGEKTFVNPRNAAAGSLRQLDSRITAMRRLTFFAYGIGAYHEDQPIFSTHSEILAYLATQQFLVARQSSTVMGANGLLAYYREMNAVRLSLPYEIDGVVYKVNDLAQQEKLGYVSRAPRFAIAHKFPAQEVSTELLAIEIQVGRTGALTPVARLAPVFVGGVTVTNATLHNEDEVQRKQIMIGDTVIVRRAGDVIPEVVAVIVERRPTHAQAFVMPDHCPVCGSKAVRLPDEAVTRCTGGLYCPAQRKQAILHFASRRAIDIDGLGEKLVDQLIDRELVHTPADLYRLDIDTLAGLERMAGKSARNLVTAIEDSKKTTLPRFIYALGIRHVGEATAKALASHTGDLDRLMDMNAEQLQQIPDIGPIVAQSIADFFSEAHNREVIEQLLSCGLQWEKPSHIAQPSSRTNLAVPGKTFVLTGTLPTMTRDQAKNRIEQQGGKVTGSVSSATSYVVAGSDPGSKYARAIELGIPVLDEDQLLSLLRDTSSSE", "output": "DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA."}]}
+{"id": "function_test_1391", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MVYAHNLGFPRIGIKREMKKTVEAYWRGEISQQQLQQQAIELQLTNWKIQAEAGVDLIPVGDFSWYDHVLDMAVRVGAIPSRFKALNSNITDTMFCMARGQAPNGIETSACEMTKWFDTNYHYIVPEFTTNQSFELHHDDLFKSTKLALENNYRAKPVILGPLSFLWLGKCKGESFNKLLLLEKLLPVYAEIFEQLSSLGVEWVQVDEPILVLDLPPEWQQAFLTTYQQLNFFNLKCLLATYFGSLDDNLSLTCQLPVDGLHIDYCRAPDQLDSVLSQLPAEKILSVGIIDGRNIWCNDLNRSLTLLENIQSSLGDRLWVAPSCSLLHVPIDLDQENKLDVELKSWFAFAKQKVAEAAFLTRGLREGRESIGAELKKNEEVIISRKTSKRIHNPNVEKKAASVTERLMRRQHEHSIRKNKQTAQLNLPLFPTTTIGSFPQTSQIRCLRRDYKQGKIDDALYEEKIRQEIAEVIGIQVKLGLDVLVHGEPERNDMVEYFGELLDGIAITSNGWVQSYGSRCVKPPIIFGDVSRERPMTLRWIEYAQSLTTKSVKGMLTGPVTILAWSFVRDDQPRSQTAKQIALALRDEVQDLERSGVRVIQIDEPAFRECLPLRKAAWQDYLEWAVKCFRLASCGVKDETQIHTHMCYSEFNDIIEAIAALDADVITIESSRSEMEILKSFEKFAYPNDIGPGIYDIHSPRIPRVAEIEELAVRALQYIPIERLWINPDCGLKTRNWEETKEALSRMVDAAKHLRKAFSSEKTPTIDLELQPAST", "output": "Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation."}]}
+{"id": "function_test_1392", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MQLIYQCAWIVPLCPLISSILIGLGLLFFEKSTKSIRRICAISCILSLSVATVICYNLSYEQIIDNSIYQYSWSWISNGDIVLEFGYLIDPLTCIMLVLVTSVAIIVMIYSDGYMSHDEGYVRFFVYLSLFTASMLGLVLSPNLIQIYIFWELVGMCSYLLIGFWFTRPSAANACQKAFITNRIGDFGLLLGILGFYWITGSFEFENLFKGFKDLLINNEVSPFFAILCASFLFLGPVAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIYLVARMFPLFETLPFVMSVISWTGAVTALLGATLAFFQKDLKRGLAYSTMSQLGYMMLALGIGSYRAGLFHLITHAYSKALLFLGSGSVIHSMEPIVGYRPDESQNMIFMGGLRKHMPITGTTFLLGTLSLCGIPPFACFWSKDEIIADSWLYSPFIGWIALLTAGLTSFYMFRIYFLTFEGEFRANSFKENTPVSSVSLWGEFRFEEFGEKKADSVLQIVEKSSPKEFFRFVQSNRESSETQIGNYLSAYPSKEPIHFLYPKESDYTMLIPLLILSIPTLLIGFIGAPLPNGQLGSDLLSHWLNSFGNLSPERLSENWLEFIEDAITSISIASFGIFSAFILYGPASIFPRDLEKKIEPQLKGVWGFFINYMYNWSQYRGYIDQYYNKIFVEGTRILAYASSFFDRWIIDGIVNGTGISSFSGGEGMRYGEGGRVSSYLFGLVFGMTILLAVILLII", "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity)."}]}
+{"id": "function_test_1393", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSIYTNSKPWTVPALAEAKRNGSKIVMLTAYDAGFARILDANGVDLILVGDSLGMVVQGHDSTLPVSVHDMVYHTACVARGVRHAMLVVDLPFQADASPERALEAATALLRVGAQMIKIEGAGHKLEVISYLVEREIPVCSHLGLTPQSVLRFGGYKVQGRGEEAGGRLRAEARAAVEAGATLLLLECVPSQLAAQITTDASVPTIGIGAGAGCDGQVLVLHDLLGLDSGHPRPKFVKDFLAHGGSVAGAVRAYANAVRDGSFPDVEHTYTS", "output": "Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate."}]}
+{"id": "function_test_1394", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSDNSQKKVIVGMSGGVDSSVSAYLLKQQGYQVEGLFMKNWEEDDNEEYCTAAEDLADAQAVCDKLGIHLHTINFAAEYWDNVFEYFLAEYKAGRTPNPDILCNKEIKFKAFLEFADEVLEADYIAMGHYVRRSFPENGEKPQMLRGLDSNKDQSYFLYTLSHEQVARSLFPVGDLEKPEVRRIAEEQGLITAKKKDSTGICFIGERKFTEFLGRYLPAQPGNIETPEGEVIGQHQGLMYHTLGQRKGLHIGGRKGGGGNEDPWFVGEKDLDRNVLIAVQGKDHPMLKSEGLLASQLHWVDREPIRDVMKCTVKTRYRQQDIPCTIIPIDDENIKVIFDEPQIAVTPGQSAVFYKDDVCLGGGIIEQRIKYSQA", "output": "Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34."}]}
+{"id": "function_test_1395", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MHDIKSIRDNPQAFDAGLARRGLKPLSASLLAIDERRRAAILASEQAQARRNAASKEIGDAKKAKDEARAATLMAEVAELKTTMPQLEAAAKAADEELTKELSAIPNIPFDEVPDGVDEHGNVQHHVFGNKRNYGFAPKLHDDLGNALGYMDFEAAAKLSGARFVVLKKGLARLERAIGQFMLDLHTTEHGYTEINPPLLVRNEVMFGTGQLPKFEDDQFWAIKGELLASPDHERLKTERLGLIPTAEVSLTNLARESILDEKQLPMRLTALTPCFRAEAGAAGRDTRGMIRQHQFTKVELVSITTPEASKDELERMLSCAEQVLQKLDLHYRVMTLCAGDMGFSSQKTYDIEVWMPGQGDGGMFREISSCSVCGDFQARRMDARSRGPDGKPRFVHTLNGSGTAVGRALIAVMETYQQEDGSIAVPSVLQPYMGGLKVISRD", "output": "Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)."}]}
+{"id": "function_test_1396", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNFLCKIVKNCRDEDTQKPSPASAPPDGDDLWLPPPEYVPLKELTSKKNMRNFCINGEVKVCSPNGYSFRILRHILRSFDEIYSGNHRMIGLVKVVVGLALSGAPAPEGMNWVYKLRRTLIFQWADSRGPLEGEELEHSQEITWDDDTEFVGLQMRVSARQCHIQGRIWCIDMNSRACQLWSDMSLQTQRSEEDKDSSLLLE", "output": "Plays a major role in assembly, budding and uncoating of virion after membrane fusion. Completely covers the ribonucleoprotein coil and keep it in condensed bullet-shaped form. Inhibits viral transcription and stimulates replication. Plays a major role in early induction of TRAIL-mediated apoptosis in infected neurons."}]}
+{"id": "function_test_1397", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNKEQVSKKIESLIELLNQYGYEYYVLDNPTVPDAEYDQKLRELQQLEQDFPDLVMENSPTQRVGGAPLASFQKVTHNVPMLSLGNAFNEQDLRDFARRASNGTDQPISFVCELKIDGLAISLTYENGKFVRGATRGDGTIGEDITSNLKTIRSIPLSIKEQGTLEVRGEAYMPHKSFLALNELREKNEEEPFANPRNAAAGSLRQLDPKIAAKRNLDIFLYGVGEWENSDLTSHSEHLTRLKELGFKTNKEWKKCNTIDEVIEYVNYWTEHRNDLSYEIDGIVIKVDSLDQQEELGFTAKSPRWAIAYKFPAEEAMTTLRDIELSIGRTGVVTPTAILDPVRVAGTTVQRASLHNEDLIREQDIRIGDKVVIKKAGDIIPKVVRSVVEQRNGDEQEFHMPDECPACGNELVRLEEEVALRCINPNCPAQLMEGLIHFVSRNAMNIDGLGEKVIIQLFQENLVQTMADLYRLDKEELLQLERMGEKSVTNLLEAIEKSKENSLERLLFGLGIRFIGSKAAKTLAMEFETMENLQKATYEDVLAIDEIGDKMADSIVQYFAEEKVTELLSNLRELGVQMEYKGPRKSEQATDSVLSGKTVVLTGKMEKFSRKEAKEIIESLGGTVTGSVSKKTDIVIAGEDAGSKLDKAEKLGIDVWSEQQLEDVVGK", "output": "DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA."}]}
+{"id": "function_test_1398", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNSHYQNHSLENFFSTNLSATDDAVFAGIQAEFTRQNEQIELIASENIVSKAVMQAQGTCLTNKYAEGYPGRRYYGGCEHVDTVEAIAIERAKKLFNCEYANVQPHSGAQANGAVKLALLQPGDTIMGMSLDAGGHLTHGARPALSGKWFNAVQYGVDKETLEINYDDVRALAVEHKPKMIIAGGSAIPRVIDFAKFREIADEVGAILMVDMAHIAGLIATGAHPSPLPHAHVVTTTTHKTLRGPRGGMILTNHEEIIKKINSAVFPGLQGGPLMHVIAAKAVAFGEALGPEFKTYIDSVIDNAKVLAEVLQTRGCDIVTGGTDTHLMLVDLRPKGLKGNKAEEALERAGITCNKNGIPFDTEKPMITSGVRLGTPAGTSRGFGAEEFKLIGHWIGDVLDGLVENPEGNAEVEQRVRKEVKALCSRFPLYQ", "output": "Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism."}]}
+{"id": "function_test_1399", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSKLYDLVSDYAPSGDQPTAIKQLTEGLDAGLAHQTLLGVTGSGKTFTLANVIAQAQRPAILLAPNKTLAAQLYGEMKAFFPNNAVEYFVSYYDYYQPEAYVPTTDTFIEKDSSVNAHIEQMRLSATKALLERKDAIIVASVSAIYGLGDPEAYLQMMLHIRRGDVMDQRDILRRLAELQYSRNDIAFERGQFRVRGEVIDVFPAESDQDAVRIEMFDDEIDCISVFDPLTGVVKQRDLPRFTIYPKTHYVTPRERILQAIENIKQELRERQTYLRDNNKLLEEQRISQRTQFDIEMMNELGFCSGIENYSRYLSGRAEGEPPPTLFDYLPHDGLLIIDESHVTVPQIGAMYKGDRSRKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIFVSATPGNYELEKSAGEIADQVVRPTGLLDPVLEVRPVATQVDDLLSEIRIRAVKDERVLVTTLTKRMAEDLTEYLHEHDVKVRYLHSDIDTVERVEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNLHGKAILYADSITKSMKKAMDETERRREKQQAYNEKMGIQPQALKRNIKDIMELGDITKSRKQKVSKTVPLSKVAEPSLSYNVLTPQQLEKEITKLEAQMYKHAQDLEFELAAQKRDEIEKLRQQFIANS", "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage."}]}
+{"id": "function_test_1400", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSFKDLRDFLNHLEKKGQLKRITHPVDPAYEMTEISDRTLRAGGPALLFENPIGYDIPVLTNLFGTAERVAMGMGREQVKELREVGQWLAYLKEPEPPKGFKDALDKLPVFKQVLNMPVKRLRKAACQEVVWQGEEVDLDKIPVMSCWQDDVAPLLTWGLTITRGPNKKRQNLGIYRQQKIAKNKIIMRWLAHRGGALDLRDWMEKYPGKPFPVSVAFGADPATILGAVTPVPDTLSEYAFAGLLRGSKTEVVKSVSNDLEIPASAEIVLEGYIDPNEYADEGPYGDHTGYYNEKEKHHVFTITHITMRKEPIYHSTYTGRPPDEPAVLGVALNEVFVPILQKQFPEIEDFYLPPEGCSYRMAVVTMKKQYPGHAKRVMMGVWSFLRQFMYTKYVVVCDESVNARDWDDVVKAMTENMNPILDSLFIESTPIDSLDFASPVAGLGSKMGLDATIKWEAELALQGATVSTEFASQIGIDVNALKAVHPLISDIYVPAVASGQFMVVKINKTHAGQCKEVVESLWQVESVKQRNKFIVVCDDDVKADDWHDIIWAITTRMDPARDTLKIDGSESCSAKLVFDATNKYPEEITREWGKPIKKDPKLVAKVDALWQEFGIL", "output": "Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol."}]}
+{"id": "function_test_1401", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQESGLKPILWKNKELILLDQRVLPGTTSYITAKTLEDCIFAIREMVVRGAPAIAITGAFGITLYWNSLVSKPSFSELKLKLSELLESRPTAVNLRLAIEEFSSRFPESNYSSFSLEEIQKGAEELALFMLSEDLENNLTLSKYALSLFPKQPSSLNIITHCNTGALATAGHGTALGVIRSLRDAGHSLTVFADETRPYLQGARLTAWELQEEKIQSFLITDNMAGWVMSSRKIDAVIVGADRIASNGDTANKIGTYPLAIVAKHHGVPFYVAATAKSMDFRIPNGSYIPIEMRKEEEITSFGFLKDSDGKPLLKEGVIAPKGMKALNPSFDVTPASLITGIITEKGIVSPVTEENLKKIFQLI", "output": "Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P)."}]}
+{"id": "function_test_1402", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MESTTEVELSRLPDSLRGRILVTGAGVSGTGIAGMLHDLGLDVVVAEDNETSRHRLIELLDVDVVGTEHARASLGDYSIVVTSPGWRPDSPVLVDAASRGLEVIGDVELAWRLDRAGVFGVSRTWLAVTGTNGKTTTTAMLAAMMKQGGFNAVAVGNIGVPVSAALTSCDRVDVMVAELSSFQLHWAPTLVPDAGLVLNLAEDHIDWHGSFRDYALAKTRVLTAPVAVIGADDSYLVELTTELGLSGLIGFTLGEPGPRQLGVLNGHLVDNAFAAQLPLAPADGINPSGPAGVLDALAAAAVARSQGVSAEDIAGALATFEVSGHRGQVVAEDHGVQFIDNSKATNPHAADTALAGRESVIWIVGGQLKGADISELVATHAHRIKAALVLGADRAEIVTAVEQHAPDAMIRVTDSTDPVAAMRELVDHAFRFAEPGDCVLLAPAAASLDMYKGMGQRGDIFAEAVLSTIEGQKEK", "output": "Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)."}]}
+{"id": "function_test_1403", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDITIVNHPLVASRLTLMRDERSDNAAFRAAASDLGAMLIYEASRDLAVEHFDTQTPVAVAEGTRLEKPPIIVPIIRAGLGMIDPALSMIPDAQVGFIGLARDEETHEPVPYLEALPEDLSDQPVFLVDPMLATGGSLLHAIRLLAERGATDITAICMVSAQPGVDALKNSGLPCRLVTAAIDPELNEDAYIVPGLGDAGDRLYGPRNIEL", "output": "Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate."}]}
+{"id": "function_test_1404", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLLKGFMLSLVLYAVYHLASNGGQFMFDFSGQSKWERAQSEVRQAILDSWHTYEKYGWGYDVYHPIKQEGENMGPKPLGWMIVDSLDTLMIMDCPEEVSRARDWIKNDLDYTFDYNVNTFETTIRMLGGLLSAYHFSNDDVYLDKAVQLANALHGAYDSPSGIPYSSVNLKSGKGIKNHVDNGASSTAEAATVQLEMKYLSKLTGEILWWNLAEKVMQVLESNKPQDGLVPIYVNPDTGKYQGHLIRLGSRGDSYYEYLLKQYLQTNKQELVYWDMYRESVEGVKKHLVSDSYPSGLTFIGELDNGIGGKLSTKMDHLVCFYGGLLALGATGGLTLNEAQSLKSWNEEREADFKLGEELTYTCYKMYHDVSPTGLSPEIVVFNEDTSKSKDFIIKPLDRHNLQRPETVESLFYLYRLTGDVKYREMGYEIFQNFIKYTKVVNSEGEVSFSSLSDVTSFDSNGLPKFKDNTESFWWAETLKYLYLLFDDTNKIPLTDYVFNTEAHPFPRFDTNDYFKTGWRRKIDENEKAQMRESKVIDKSNLPEAQPVDKSADQEAKEIIEEIAG", "output": "Involved in the maturation of Asn-linked oligosaccharides. Trim a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2) (By similarity)."}]}
+{"id": "function_test_1405", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPATYPEYPSSLSYSAMEAQIREFWIERNIFRKSLEKDAPKGIYSFYEGPPTVNGKPGVHHLFSRTIKDVVCRYHTMQGYQVPRKAGWDTHGLPVEISVEKKLGLKNKSHVEEYGVGEFNREARALVYHHIDDNREGWGKLTERMGYWVDMDSPYITCDNNYIESVWWALKTIFDKGLIYKDYKIVPQDPKSETVLSSHELALGYKEVQDPSVYIKFRLKDSGESILVWTTTPWTLISNVALAVGRDIDYVRVKHRETGEVLILAESRLSVLVEKIGDESAWEVIDRCKGSDLEGRDYEPLFNYFSPERRAWYVVCGDFVSTGEGTGIVHIAPAFGADDYELSKQYQLPMLQPVARNGCFTAEVPDYEGMFFKDADKPIMQRLKEEGKLYRRETIQHTYPFSWRYDVPVIYYARESWYIRTTDIAPRMVALNKTINWNPPEIGTGRFGNWLEENKDWALSRERFWGTPLPVWVAEDFAIGDGPDSGKLFAVGSVAELREGFIEIDGEEMNLGDALDKGLVELDLHKPFVDRIWFIRDGKRFNRTPELIDVWFDSGSMPFAQLHYPFENKELFDKTFPADFIAEGVDQTRGWFYTLHAIATLIFDRPAYRNVVVNGHILDKSGQKMSKSKGNVVDPFESMEQYGADAIRWYLMITSPPWRPKLFNAAEIEEEQRKFFRAFINSYNFFVLYANVDGFRYEEADIPFTQRSELDRWVLSSLNTLIAEVTSRMEQYDLTGACRLIGDFTVDDLSNWYIRRSRKRFWKGEMGPDKLSAYQTLSTVLETLAKLMAPFVPFIAEKIWLDLKSVGGTSKAESVHLADWPVADESCIDAALEERMKKAQIITSLVRTMREKAGIKVRQPLRRILLAAAEPGSRAAYELVSDIIKEEVNVQKIEYVEDEDGSVISKKAKPNFKTLGPRFGKDMKLLAEEIRIMSHKQISRLEKEGSIEIDLGGRICTVLREDVDIVHEDIEGWLVAADDAHRIMVALDTEITEELEMLGLARELVSRIQTLRKESGLEITDRIALTIAGSEKLLAAARKSESYIMDETLATSIVLLPLDDSQPGDGVEQVNNELCRLSLEKSGS", "output": "Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)."}]}
+{"id": "function_test_1406", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAKAKFERTKPHVNVGTIGHVDHGKTTLTAALTKIGAERFGGEFKAYDAIDAAPEEKARGITISTAHVEYESPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLSRQVGVPHIVVFLNKADMVDDAELLELVEMEVRELLSKYDFPGDDTPIIHGSARLALDGDQSDIGVPAILKLVEALDSFIPEPTRDVDRPFLMPVEDVFSISGRGTVVTGRIERGIIKVGDEIEIVGIRDTQKTTVTGVEMFRKLLDQGQAGDNAGLLLRGTKRDDVERGQVLCKPGSIKPHTEFEAEVYVLSKDEGGRHTPFFKGYRPQFYFRTTDITGACQLPEGVEMVMPGDNVKMVVTLINPVAMDEGLRFAIREGGRTVGAGVVAKIIK", "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."}]}
+{"id": "function_test_1407", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTHLRFDNRLRQQLPGDPEEGSRRREVSVAWSAVLPTPVAAPSLIAHSAEMAQVLGLDAAEIASAQFAQVFGGNALYPGMQPWAVNYGGHQFGHWAGQLGDGRAISLGEAIGTDGGRYELQLKGAGPTPYSRGADGRAVLRSSIREFLCSEAMHHLGVPTTRALSLVGTGDAVVRDMFYDGHPQREPGAIVCRVAPSFIRFGNFELPSARGDIALLRQWVDFTIARDFPALAGAGEALYAGWFAQVCERTAVMVAHWMRVGFVHGVMNTDNMSILGLTIDYGPYGWVDDYDPDWTPNTTDAQGRRYRFGTQPQVAYWNLGRLAQALAPLFPDQAPLQHGLDRFRDTYLACDRHDTAAKLGLAECRDEDLQLIDALRALMRESEMDMTLTFRGLIDLSPDHPDPAQLREAFYDEDKRVADAPQLQQWLQRYAARLQQDPLPPDARRARMRLANPRYVLRNYLAQQAIDRAEQGDPSGVQELLEVMRHPYDDQPGRDAFAARRPEWARDRAGCSMLSCSS", "output": "Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation)."}]}
+{"id": "function_test_1408", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRASISKSSIKGEVFAPPSKSYTHRAITLAALSKESIIHRPLLSADTLATIRASEMFGAAVRREKENLIIQGSNGKPGIPDDVIDAANSGTTLRFMTAIAGLTDGITVLTGDSSLRTRPNGPLLEVLNRLGAKACSTRGNERAPIVVKGGIKGSEVEISGSISSQFISALLIACPLAENSTTLSIIGKLKSRPYVDVTIEMLGLAGVKIHTDDNNGTKFIIPGKQKYDLKQYTVPGDFSSASYLLAAAAMLEGSEITVKNLFPSKQGDKVIIDTLKQMGADITWDMEAGIVTVRGGRKLKAITFDAGSTPDLVPTVAVLASVAEGTSRIENAEHVRYKETDRLHALATELPKMGVSLKEEMDSLTITGGTLEGAEVHGWDDHRIVMSLAIAGMVAGNTIVDTTESVSISYPDFFKDMRNLGAKVKEIPEE", "output": "Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate."}]}
+{"id": "function_test_1409", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKKIEVRDLDLFYGEVQALKKINLDVEPNSVLALIGPSGCGKSTFIRTLNRMNDLIEGVKISGTVLLDGKDIYKEVDVIELRKKVGMVFQKPNPFPMTVYDNVAYGPRIHGIRDKRTLNEIVEKSLKAAALWDEVKDRLHHSALSLSGGQQQRLCIARTLAVEPEVILMDEPTSALDPISTMKIEELIEELKKKYTIIIVTHNMQQAGRVSDYTAFFLNGELVEWGPTDQVFYNPKDKRTEDYITGRFG", "output": "Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system."}]}
+{"id": "function_test_1410", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKKNIIIGSRGSILALAQANLVKDRLQGNYPNLSFEIKEIVTSGDKDLKSNWENSDISLKSFFTKEIEQELLDGEIDIAVHSMKDMPAVSAKSLICGAIPDREDPRDVLVSKNGLLVTLPQGAKVGTSSLRRAMNLKTVRPDFEIKHLRGNIHTRLKKLETEDYDAIVLAAAGLKRTGLADKITEYLNGEVFPPAPAQGVLYIQCRENDEEIKEILKSIHNEAIAKIVEIEREFSKIFDGGCHTPMGCYSQVNGDKIKFTAVYLDEGKQIRAVVEDDLAKGKEIAYMAAEEIKNKIVK", "output": "Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps."}]}
+{"id": "function_test_1411", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MMSNEKEMTGTTIIAIKYDDGVLIGADSRTSMGAYVSSRVTDKLTQITDKIFVCRSGSSADTQMISSYLRMYLSMYSQLEDSIPQVQRAAALASKIIYENPSLLAGLIVAGYDDKPRVFNISLGGSLTERDWAIGGSGSAFIYGYCDVNWRSGMSLEEGIRFVRNAVSCAINRDNASGGCIRMSAISRTGVQRYFYPGDKVLQ", "output": "The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity (By similarity)."}]}
+{"id": "function_test_1412", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDEGTRTVLRKFEHIEHCLKRNVEAHATNGFEDVHFVHMSLPEIDKDEIDLSVKFLGRKFDYPIMITGMTGGTRKGEVAWKINRTLAQAAEELNIPLGVGSQRAMIEKPETWESYYVRDVAPNVFLVGNLGAPQFGRNAKRKYGVKEVLYAIEKIDADAIAIHMNPLQESVQPEGDTTFSGVLEALAEITSSIDYPVIAKETGAGVSKEVAIKLESIGVSAIDISGVGGTSWSGVEYYRAKDELGKRLALRFWDWGIKTAISLAEVRFSTNLPIIASGGMRDGITMAKALAMGASLVGIALPVLKPAAKGDVEGVIKVIKGYVEEIKNAMFLVGARNVEELRKVPIVFTGFVREWLEQRIDLQEFVKKRAKLRFEFWNVGFYSYPYTSSSTHLF", "output": "Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)."}]}
+{"id": "function_test_1413", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MARVTVEDCIDKVDNRFELVLLASHRARQISQGSSITVDRDNDKNPVVALREIADETLSPDDLKEDLIHSLQKHVEVDEPEPDPVTLAASAADGEDDDQPETVTFDQMSEEELLAGIEGLVPPEKNDDY", "output": "Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits."}]}
+{"id": "function_test_1414", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKIFYKAINMTLSMFTVIPSPKYEWDDRAAKHIMKLYPFIGLIIGALWYLSFFVLSKLNVPIMLMAALILTVPYILTGFLHLDGFMDVSDALLSRRDKETKLRILKDSTVGAFSVISVVLLLLVEFAGMFTVLNKNLDMRVLIFIPIASRAINGYFIVSQEMLGQSSLAKFFKEGTGKVDEIILLGIYVLVALITFFTLGINYLIAILAMGLISFILLLKVKKELGGINGDVAGYILVLMEFTGILLLGII", "output": "Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate."}]}
+{"id": "function_test_1415", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKKVVVGLSGGVDSSTAAAILHNQGYEVIGLTLWLMKGKGQCCSEGMIDAAYICEQLGIPHEVVDMRDVFQTHIVDYLVTGYGAGITPLPCSQCNKTVKFGPMVQYASEKLGCDRIATGHYARIRYDEATGRYQLLRAVDRNKDQSYFLYDLSQDLLAASLFPLGEMEKADTRRIATEHGLKTADKPESQDLCLVESNGSMRAFLDKYIAPKKGDIVDTAGKVLGQHDGVHHYTIGQRKGLGIAAPEPLYVVELDAVHNKVVVGDRTKATQEECTVNRVNWVSIAEPSTPIRAAVQIRYRSAPEPVTVIPLENSRVRLVFDEPQFSITPGQAAVWYDGNKVLGGGIIEQFSK", "output": "Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34."}]}
+{"id": "function_test_1416", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPVTAMCLQDSKKLKKAKLTRKKVTPFPFSRMVLCLSLVFTLYVEATNARCLRPRSKELLCGSELVDILQFICGPTGFYVSKGASFRNRNRPGIVEECCFCGCSVAILESYCAAPVTNFTGREEQKS", "output": "The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. Promotes anterior neural development."}]}
+{"id": "function_test_1417", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAQWPEKEEEEQPMFGEEYTGYIPSYLEKDEPCVVCGDKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYDCCCIIDKITRNQCQLCRFKKCIAVGMAMDLVLDDSKRVAKRRLIEENRERRKKEEIVKTLQNRPEPTGAEWELIRMVTEAHRHTNAQGAQWKQKRKFLPDKIGQSPVAPTSDGDKVDLEAFSEFTKIITPAITRVVDFAKKLPMFSEQLPCEDQIILLKGCCMEIMSLRAAMRYDPESETLTLSGEMAVKREQLKNGGLGVVSDAIFDLGKSLAQFNLDDTEVALLQAVLLMSSDRSGLTCMDKIEKCQETYLLAFEHYINYRKHNIPHFWPKLLMKVTDLRMIGACHASRFLHMKVECPNELFPPLFLEVFEDQEV", "output": "High affinity receptor for triiodothyronine."}]}
+{"id": "function_test_1418", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAEEQQKAGHSNGENIIPPEEVAKFLPETVEEGGWEKCWEDGITPWDQGRATPLVVHLVDSSSLPLGRALVPGCGGGHDVVAMASPERFVVGLDISESALEKAAETYGSSPKAKYFTFVKEDFFTWRPNELFDLIFDYVVFCAIEPEMRPAWAKSMYELLKPDGELITLMYPITDHDGGPPYKVAVSTYEDVLVPVGFKAVSIEENPYSIATRKGKEKLGRWKKIN", "output": "S-adenosyl-L-methionine-dependent methyltransferase. Probably involved in glucosinolate metabolism and defense against phytopathogens. Highly reactive to thiocyanate (NCS(-)) derived from myrosinase-mediated hydrolysis of glucosinolates upon tissue damage. Also accepts halid ions as substrates with a lower affinity."}]}
+{"id": "function_test_1419", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTILYAVIACGLLSVLYAIWATRSVLASDQGNARMQEISAAIREGAQAYLARQYTTIALVGVVVLLLAWWLLSITAAIGFLIGAVLSGAAGFIGMHVSVRANVRTAQAASNSLAAGLDIAFKSGAITGMLVAGLALLGVSIYYLILTGPMGLQPNDRIVIDSLVALGFGASLISIFARLGGGIFTKGADVGGDLVGKVEAGIPEDDPRNPATIADNVGDNVGDCAGMAADLFETYAVTVVATMVLGAIFFGGTAVLGAAMLYPLAICGACILTSIVGTFFVKLGANGSIMGALYKGLIVTGLLSIVGLAVATSVCFGWGEIGTVAGMVITGKNLFICGLIGLAVTGLIVVITEYYTGTNKRPVNSIAQASVTGHGTNVIQGLAVSLESTALPAIVIVGGIISTYQLAGLYGTAIAVTTMLGLAGMIVALDAFGPVTDNAGGIAEMAGLPKEVRHSTDALDAVGNTTKAVTKGYAIGSAGLGALVLFAAYSNDLKFFAANGDKYPYFQGMGEISFDLSNPYVVAGLIFGGLIPYLFGGIAMTAVGRAAGAIVEEVRKQFREDPGIMAGTSKPNYARAVDLLTKAAIREMIIPSLLPVLAPLVVYFGVLLISGSKASAFAALGASLLGVIVNGLFVAISMTSGGGAWDNAKKSFEDGFTDKDGVKHLKGSEAHKASVTGDTVGDPYKDTAGPAVNPAIKITNIVALLLLAVLAHG", "output": "Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force."}]}
+{"id": "function_test_1420", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSLSIDVTSLPSISSSIYKHESSSTTSTLSGKSIGRSEQYVSPDAEAFNKYMLSKSPEDIGPSDSASNDPLTSFSIRSNAVKTNADAGVSMDSSTQSRPSSNVGCDQVDFSLSKGIKVNANLDSSISVSTVSKKEKSKSDHKNRKHYPRIEADSDSDEYVLDDSDSDDGKCKNCKYKKKYFALRMRMKQVAMQLIEDL", "output": "Plays an essential role in the viral genome replication. Participates, together with NSP2, in the formation of viral factories (viroplasms) which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place. Orchestrates the recruitment of viroplasmic proteins such as capsid proteins to these factories."}]}
+{"id": "function_test_1421", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MELAYLHTRPEQYARLKAECADFIVKENLGYEMSGDGEFVAVKVRKTDCNTLFVGEKLAQFVGISERNMGYAGLKDRKAVTEQWFCLHMPGQPTPDFRSFQLEGVDILEVTRHHRKIRTGSLEGNHFEILLRGAKETDELNVRLNNIKQCGFPNYFTEQRFGRDGHNLTQALRWAQGEINVKDRKKRSFYLSAARSEVFNLVVSERIALQLAQQVLRGDMLQLQGSHSWFQADEKEDLNALQARLEQQDILLTAPLIGEQNPPATDIENQLVEQHQALLTLMAKERMKAARRPMLMQAQALQWAFVAEGLKLAFYLPAGSYATALVREVVNVQED", "output": "Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs."}]}
+{"id": "function_test_1422", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MASQGTKRSYEQMETDGERQNATEIRASVGRMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSAFDERRNRYLEEHPSAGKDPKKTGGPIYKRVDGKWMRELVLYDKEEIRRIWRQANNGDDATRGLTHMMIWHSNLNDTTYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTMVMELIRMIKRGINDRNFWRGENGRKTRSAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFSARSALILRGSVAHKSCLPACVYGPAVASGYNFEKEGYSLVGIDPFKLLQNSQVYSLIRPNENPAHKSQLVWMACHSAAFEDLRLLSFIRGTKVSPRGKLSTRGVQIASNENMDTMESSTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPAFSVQRNLPFDKSTIMAAFTGNTEGRTSDMRAEIIRMMEGAKPEEMSFRGRGVFELSDEKATNPVVPSFDMSNEGSYFFGDNAEEYDN", "output": "Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway. Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus."}]}
+{"id": "function_test_1423", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MILNDSTIMRMVSDGLLISENFDRGCLTPNGYDLRVDAIDVEGRQYSEFEIGKNVHFLVSTIEILKIPDDVVGMIWTRSSFARKGIFGSFGAIDAGYHGNLTLSFFNAGSAVNLRRGERIAQIVFVKMIGSAEKPYHIRSGNYQNSRGIVKDPVAGSQIASEAKKN", "output": "Catalyzes the deamination of dCTP to dUTP."}]}
+{"id": "function_test_1424", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MHVLDGSSGGGQLVRTALTCAAVSGESFRMRYVRRARSNPGLQAQHCAAVNAVADICDAATDGVEVGSEAFSFEPEVAAEEADDDEEPTLGGTTSVEVGTAGSIPLVFDSLLPLAGALDEPITATLTGGTDAKWAPPMDYFQHVKLPLLREHGIDATVSVDRRGFYPRGGGEATLTVEPSTPTPITLTERGDREALTAYSVAESSLADDEVAEQQATAAAPDAAHEIAYTDADSAGSAVVLAAEYEHSRAGFAALGERGVSADAVGENAADALAAFESGPGAVDSHLADQLVPVVAVAGGEVRAPEVTTHIETCVDLLAEFDYDIDIEHTDDGAVVLSA", "output": "Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing (By similarity)."}]}
+{"id": "function_test_1425", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNTLLWTILLPLLFSFCVCQQPEHQDLEMSVQYYDDNVIDLLEALNVTRSVKGVTKAKGSDPASPAWKFRQRVPHLTLPRDYSVYLLSTTQESLGLHFVAKQAKNNRGTLVAFLSPAATKIDGRPLLRLISDTHTDQLYFEYRTAQTMEPASLHFPGSSPFSGSQWARVALNVNTHKVTLFLDCEEPVVFGKEGAEEMLSLILPLDLEITFASTPSDKESKFLGYWQTAEISPTGFTRRPWHCENRSDSLPLPYSLSGERQMEDEEIQREPRAPDLSDTDHYQQQQSEVPAQLLAKDDRLQRLEEAVKGLTNMIDMIKSQNADLQARVIALESCECRRSTCVWEDKEYQDSETWKKDACNICVCVGGSVTCSVRKDWPQCLGCFHEGRNYNNKDIFSVGPCMSCICQSGEVSCTPKLCPPVTCSDPVTLPNECCPLCATGCSDGHKEGDTWRKDTCTTCTCQNGTISCEREQCPELTCLKRHTPPGQCCAKCQQGCEYEGLIYRNGDYFLSQSNPCVNCSCLNNLVRCLPVQCPLPACTNPVPIPGQCCPSCPVCELDGHPLIPGQNVTTKDGCRLCSCQDGKVQCTESVQCPHICTHGVRSNSCCLDCSACEMHGDIIPNGLTFQGNMDPCESCTCQDGNVHCVRVSCPELSCVLHEKIPGECCSQCQSCMDGTVKRKHGEEWKPQGDPCQSCRCLEGRVQCRKRHCAALCRNPLPPRPGTCCPMCDGCLYNGRSYLNGQPVRSTDQCNRCFCENGNVQCEPIACPQAPCRNPVRRTGECCPRCEGCEYDSRHFAEGVVFTTAHDPCLQCTCLSGEVSCEHLDRKCPPSQCSHPGKAAGQCCPSCDVCDFEGILYTDRQTFQPPGHGPCLKCFCTIGNVRCVEETCPPAPCPNPVRDPEQCCPVCKVCVQDGVEFLEGIEWELDGNPCSSCTCRNGDTVCGVSECPPVSCLHPTRREGECCPVCDSCSYNQRLYSNEQIFTDPDNPCQDCQCKDGTVQCSSIVCPPVLCTIPERTPGQCCAKCPDCRYQDQIFLEGEQFSNPLNQCQECWCRDGHVTCTDRGCTGALCSYPLPGTCCQNNCNGCNYAGKEYPNGADFPHPTDKCRQCHCINGNVQCLAQRCPPLLCAEPFPVPGECCPQCPVPPADCPYSGVTYRHMQRFYDPSDKCRDCICNNGTVTCQRKPCAPTPCLHPLQGDCCRSCDGCLMSGKELANGEQFPQPSDPCSVCVCWEGSVTCQPKTCPVLNCPFPAPGQCCKECQDCQYFGEVYLNGQEFSAPEDSCSRCVCADGFVTCSKKPCYKAGCTHPSTPPGKCCPVCDGCSYNGDALINSQSVPDPSNPLCSECTCRAGSVQCVRKLCGPTSCPHPVTGPCDCPICQGCHFQGHNYIDGEVFTSAQSQCEQCRCMRGHVTCGPRPCDQVTCPHPAEDPCMCPVCDGCNYSGRDCTNGESFPDPEDECSHCTCRNGEVACISVPCPRVSCMYPITPRGECCPRCTGICKHNGRVYQSGDTFHPPGDLCTKCSCQNEMVNCQRVRCSQECSHPVLSPASSCCPVCDRCFYENREYANHETFTSTSDPCQRCVCLDGSVTCTHVVCPYVSCANPITKPGQCCRECPVCRYQGKEFSEGAHWVPHTDPCLKCTCSNGHVDCEPPQCPPLPCTQQVTDPGTCCPRCRGCVYNGREYRDNSNWLSSSDHCMSCMCVDGVTTCSKLQCITSCTNQITIPGECCPVCADCISNSKVYLPGDSYNPSKDPCEICTCESLPNGQQYRHCTKKQCPSLLDCPRSYILPPAEGQCCSSCAQALSNCTNTLVGNEIQATDDPCYTCHCKDLTWVCVHQPCPALSCPRSEQFTHSGSCCPVCNECVVEIEGRRVPDGETWTDRQDPCVTCTCTLGHVECQIEECQPVQCQEGERKVKRPGTCCHECQASAVSCWYQGQRFLSNEHWQVDECTACTCVSGEVHCHSERCPQVSCTAEETPALIPGMCCPHCIPRPATCIAFGDPHYRTFDGKMYHFQGSCTYVLSEDCEGGDFSIHVTNDDRGLRGVSWTKEVTVLIGDAVVQLLQDWVVMVDYQTVELPFLKEPYIYIERKTNTILLNSNIGVKVQWNGRSHLEVSVPGTYRDHLCGLCGNFNNYPQDDLRDRRGQILMSEAAFGNSWRVQSSNDSSSSCWDGQDVDPCKQAGYRARKEANGRCKLLKSSVFEPCHRVVPPEMFFASCVYDLCACGAGDECLCDVLEAYASECREAGVILQWRSPALCAVGCPHDRGYVFDECGPPCPKTCFNKDVPLGVLESHCFKPCVPGCQCPAGLVEHESHCIPPESCPKIIHGNL", "output": "May be a signaling molecule that mediates inductive activities of the embryonic midline. Able to dorsalize mesoderm."}]}
+{"id": "function_test_1426", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MCNHHPQHSHDNDTIRIRGARTHNLKNIDLDIPRHKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLQMMDKPDVDLIEGLSPAISIEQKSTSHNPRSTVGTVTEIHDYLRLLYARVGTPYCPEHKLPLSSQTVSQMVDAVLKLPEDTRVMILAPTVRERKGEFVDFFADLQAQGFARVRVDGEVYQLDEVPKLEKNIKHNIDVVIDRVKVKADIKQRLAESFETALRHGNERALAMEMDSGEEHWFSARFACPVCSYSLPELEPRLFSFNNPMGSCPTCDGLGNTNFFDPEKVVAHPELSLATGAIDGWDKRNQFYFQMIQSLARHYGFDVQAAWETLPEKVKKVVLHGSGKEVIDFTYLSERGTTFNRSHAFEGIIPNLERRYRETDSETVREKLREYQNHRACPSCGGARLRKEARYVYVSGEPLHEVSAWPLTKTHQFFETLDLDGNKKQIAEKILKEITERLGFLINVGLDYLNLSRSAETLSGGEAQRIRLASQIGSGLTGVMYVLDEPSIGLHQRDNDRLLATLKRLRDLGNSVIVVEHDEDAIREADFVVDMGPGAGEHGGNVLIADTPENVAQCENSVTGQYLSGKKSIAVPSERTPVNPDRMLVLKGARGNNLKNVTLELPLGLITCITGVSGSGKSTLINDTLAKITARELNRAQEEPAPFDDIHGLEHLDKVINVDQSPIGRTPRSNPATYTGLFTPIRELFAGVPLSRERGYNVGRFSFNVKGGRCEACQGDGVIKVEMHFLPDVYVPCEVCHGKRYNRETLEIQYKGKNISQVLDMTVEEAREFFDAVPTVSRKLQTLMDVGLGYIRLGQSATTLSGGEAQRVKLALELSKRDTGRTLYILDEPTTGLHFADIALLLEVIGRLKGKGNSIVIIEHNLDVIKTADWIVDLGPEGGDGGGRIIAKGSPEQVAKVKGSYTGKYLKVVLR", "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate."}]}
+{"id": "function_test_1427", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNIADGRQAFSAPAKLNLDLRITGRREDGYHNIESIFCLIDLQDTVYLKPRDDGKIILHNPVDGMPQEVDLSYRAASLLQKYARNPAGVEIWLDKKIPTGAGLGGGSSDAATVLLVLNRWWQCGLTQRQLIDSGAALGADVPFFIFGKNAFARGIGDRLDEMDIPKQWYVIVKPPVHVSTAKIFTHESLTRNSASSIMPTFQNLQPFRNDMQAVVFKEYPEVWKAYSELSRYGFALMTGSGACVFTACQDRNSAYNIYRQVSDLYEAYLAEGLSKHPLLSV", "output": "Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol."}]}
+{"id": "function_test_1428", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSTLQSKDPKVFEAVQQELGRQRDKIELIASENFVSEAVMEAQSSVLTNKYAEGYPGRRYYGGCEYVDIVEDLARDRAKEIFGGEHVNVQPHSGAQANMAVYFTILEHGDTVLGMNLSHGGHLTHGSPVNFSGIQYNFVEYGVDKESQRIDYEEVRRLAKEHQPKMIVAGASAYPREIDFAKFREIADEVGAYLMVDMAHIAGLVAAGLHQNPVPHSHFVTTTTHKTLRGPRGGMIICNEEFAKQIDKSIFPGIQGGPLMHVIAAKAVAFGEALQPEFKSYGEAIIRNAKRLGEKLTSEGIDLVSGGTDNHLLLLDLRSLGLTGKVAEKALDDVGITTNKNTIPFDPESPFVTSGIRIGTAAVTSRGLDEEAMDEIGATIALTLKNVDNEEKMNEARERVDALTAKFPMYPNL", "output": "Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism."}]}
+{"id": "function_test_1429", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGDVVMNERELILAIETSCDETSAAVIENGTTILSNVVSSQIDSHKRFGGVVPEIASRHHVEQITVIVEEAMHEAGVDFADLAAVAVTEGPGLVGALLIGVNAAKAIAFAHQLPLIGVHHIAGHIYANRLLKELEFPLLALVVSGGHTELIYMENHGEFEVIGETRDDAVGEAYDKVARTLGLPYPGGPHIDRLAVNGEDTLQFPRAWLEPDSFDFSFSGLKSAVINTLHNAKQRGENVQAEDVAASFQASVIDVLVTKTKKAAEEYKVRQVLLAGGVAANKGLRTALEEAFFKEPIDLVIPPLSLCTDNAAMIGAAASIKFKQQTFAGMDLNGQPSLELEND", "output": "Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction."}]}
+{"id": "function_test_1430", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSHILDTINTVYPFPPKPIPLRDEEKQAYIAEIKQLLIEKDAVLIAHYYTDPEIQALAESTGGFVGDSLEMAKFGNRYPATTLIIAGVRFMGESAKILTPEKRILMPTLEAECSLDLGCPADKFTEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVEHLDSEGKPIIWGPDRHLGAYIAKKTGADMLLWQGECVVHDEFSADALRKMKALYPDAAILVHPESPASVVELADAVGSTSQLIKAAKTLPQQKMIVATDKGIFFKMQQMVPEKELIEAPTAGAGATCRSCAHCPWMAMNGLQAIAQALREGGKQHEIFVDEALRVKSLIPLNRMLDFAEQLNLKVKGNA", "output": "Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate."}]}
+{"id": "function_test_1431", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTPLALSMIIFAYLLGSISSAVLICRVLRLPDPRNVGSQNPGATNVLRIGGKKAAVAVLLCDMLKGTIPVWGGYFLNIEPFMLGLVAIAACLGHMYPIFFHFKGGKGVATALGAIAPIGLDLTAMVMATWLVVVVLFRYSSLAALVTVLLAPLYTWLIKPQYTLPVAMLCCLIVLRHHQNVKRLFAGTEPKVGEKNKKPSDDEESRVV", "output": "Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP."}]}
+{"id": "function_test_1432", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MATLQEKLITPIAAESTTPNNKITVVGVGQVGMACAISILGKGLCDELALVDVWEDKLKGEMMDLQHGSLVLQTHKIVADKDYAVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIMKYSPNCTILVVSNPVDILTYVTWKLSGLPKHRVIGSGCNLDSARFRHLMAEKLGIHPTSCHGWILGEHGDSSVAVWSGVNVAGVSLQELNPAMGTDRDSENWKEVHKLVVDSAYEVIKLKGYTNWAIGFSVADLIESMLKNLCRVHPVSTMVKGMYGIENEVFLSLPCVLSASGLTSVINQKLKDEEVAQLKKSADTLWGIQKDLKDL", "output": "Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+)."}]}
+{"id": "function_test_1433", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSRTPLDTVEHATATPDVELPWAELGLKKDEYERVVEILGRRPTGAELAMYSVMWSEHCSYKSSKVHLRQFGEKAPQSDAMLVGIGENAGVVDVGQGYAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIIAMGARPVAVVDPLRFGAADHPDTKRVLPGVVAGIGGYGNCLGLPNIGGEVVFDACYQGNPLVNAGAIGVMRHEDIHLAKASGAGNKVILYGARTGGDGIGGASILASETFDDAKPSKRPAVQVGDPFQEKLLIECTLEAFAEKLVVGIQDLGAAGLSCATSELASNGSGGMRVTLDDVPLRDSTLSPEEILMSESQERMCAVVEPEKVDRFLEICDKWDVIATVIGEVTDGDRLEIFWHGGKIVDVDPRTVAHDGPVYERPYARPDWQDALQADDANKLPRPGTSDELKAQVLKLVGSPNQASKQWITQQYDHFVQGNTVLAQPEDSGMIRVDEESGLGVAIATDGNGRYAKLDPYTGAQLALAEAYRNVATTGAKPLAVSDCLNFGSPEDPAVMWQFAEAVRGLADGCLQLGTPVTGGNVSLYNQTGEAAIHPTPVVAVLGVIDDVARRTPVAFQEDGQLLYLLGDTREEFGGSAWSQVIHDHLGGLPPKVDLERERLLGEILISASRDGMIDSAHDLSDGGLVQAVVESALLGGKGARLVVPDGLDAFTFLFSESAGRAVVAVPRSEEVRFNDMCGARGLPVTRIGVVDGDAVEVQGEFTLPLTDLREAHESTIPGLLA", "output": "Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL."}]}
+{"id": "function_test_1434", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEQKRPQLKARVDGDYGEFVLEPLARGYGVTIGNPIRRILMSSIPGTAVTSVYIEDVLHEFSTIPGVREDVIRLILNLKELVVKFHAPGPKTLTLRAQGEGEVRASAFEVPTDAEIVNPDLVIANLAEDGKLVMEVRVEEGEGYVSADKHATKDRINSIPVDAMFSPVRRVAYHVENTRVGQQTDLDRLILRVWTDGSAGPQEALDKAVEILRDELSVFGNVEPMPALESSYAAATPAAVYDPATATLPASVYDSPRQPDLGSLSINPQPFPTDQDTPRVTLEGLGLTTRVLHSLKEEGIDSVDALCALSDRDLKKVPGIGERSLDEIKQQLAQFGLALRD", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_1435", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTNIRKTHPLMKIVNHSFIDLPTPSNISTWWNFGSLLGLCLTIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNFGWLIRYIHANGASMFFICLFLHVGRGLYYGSYTYFETWNVGIILLFVVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGNTLVEWIWGGFSVDKATLTRFFAFHFILPFIITALVMVHLLFLHETGSNNPSGLISDSDKIPFHPYYTIKDILGALLLILILMILVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVSSILILLTFPLLHLSKQRSMMFRPLSQLMFWILVADLLTLTWIGGQPVEYPFIIIGQLASILYFTIILLILPAVSLIENKLLKW", "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."}]}
+{"id": "function_test_1436", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLSAARLIAPAARSAIFSNAAVVRPLAAVSTQTQLVPAAPAQLSAVRSFQTTSVTKDIDSAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGYARNPSLKQQLFSYAILGFALSEAMGLFCLMMAFLLLFAF", "output": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element (By similarity)."}]}
+{"id": "function_test_1437", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSSEITEGDLQKFHDEHFNAKAVNLWNVAFAQNDRGGNSESANVEYTQSVERYPDGTIRTLTDEQILWFRESEKRELMWKKEKEQLLKEKELRQKALDKERMVSSKPETNPKTPISLKELKDIEIYQNQFHYSAYEILEEEKILDNIFRKFTALPIKYWPATPIRG", "output": "The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs (Probable). Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core) (By similarity). In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP (By similarity). To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate (By similarity). Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP (By similarity)."}]}
+{"id": "function_test_1438", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MVKVESFELDHTKVKAPYVRKAGIKIGPKGDIVSKFDLRFVQPNKELLSDKGMHTLEHFLAGFMREKLDDVIDISPMGCKTGFYLTSFGDIDVKDIIEALEYSLSKVLEQEEIPAANELQCGSAKLHSLELAKSHAKQVLENGISDKFYVE", "output": "Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD)."}]}
+{"id": "function_test_1439", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLKFSMEFCYPQPDVKTLIVGTLGPKETSSEQTLNYLITQWQAEQISVTSHLFDTFTELKEALLQDRVDLALVPHAYERVNDFYMEPSLKLGFVFTYPTPIYGLAKRKNEELVWENCTLVTHPAPFPLLPYLLPGYPHQKNIKVEFVNSTSAAAIQVKQGLADLAITNENALKENDLEFIAEYGKIEMSWSIFHKKGTVHRE", "output": "In vivo, involved in the biosynthesis of 2-carboxy-6-hydroxyoctahydroindole (Choi) present in the nonribosomal glycopeptides aeruginoside 126A and B. AerD is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. AerD catalyzes the protonation at C8 followed by decarboxylation to produce the dihydro-4-hydroxyphenylpyruvate regioisomer A258 (H2HPP A258)(3-(4-hydroxycyclohexa- 1,5-dienyl)-2-oxopropanoic acid), which is able to undergo a nonenzymatic isomerization to produce dihydro-4-hydroxyphenylpyruvate regioisomer A295 (H2HPP A295)(3-(4-hydroxycyclohex-2-enylidene)-2-oxopropanoic acid)."}]}
+{"id": "function_test_1440", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSRTNLPIQPAKMSDATSSKPQIFSIQDLKQAASDKMSQMYRDYYNGGAMDNITLASNEAAFDRYLLRPRVLRNVSNIDMTTTLWGTKAALPLGVSPSAMHRLAHADGEVGTSKACAARNVPMILSALSNDTLEDVSGQSSDGSTPYAIQVSPFKNRQITTNLLSRAKAAGYKAVVLTVDAPMFGRRLDDLRNGFSIPPGFSFPNLSAQTQSGSGGLGGGIPDLSFDTAATWEEKIAWMKSQTDLEIWVKGVTSPLDAQIAIEQGVDGIIISNHGGRQLDTTPATIDILREIAPIAKGKTRIAIDGGFRRGSDIFKAVALGADFVFVGRIAIWGLAYDGSNGVGLALDLLINEFKLCMGLAGCSKISDITPAHLSILNAKGVLESVY", "output": "Oxidase; part of the gene cluster that mediates the biosynthesis of fusaric acid, a mycotoxin with low to moderate toxicity to animals and humans, but with high phytotoxic properties . L-aspartate is suggested as fusaric acid amino acid precursor that is activated and further processed to O-acetyl-L-homoserine by cluster enzymes aspartate kinase FUB3 and homoserine O-acetyltransferase FUB5, as well as enzymes of the primary metabolism (By similarity). The polyketide synthase (PKS) FUB1 generates the triketide trans-2-hexenal which is presumptively released by the hydrolase FUB4 and linked to the NRPS-bound amino acid precursor by NAD(P)-dependent dehydrogenase FUB6 (By similarity). FUB1, FUB4, and the non-canonical NRPS Fub8 may form an enzyme complex (By similarity). Further processing of the NRPS-bound intermediate might be carried out by FUB6 and the sulfhydrylase FUB7, enabling a spontaneous electrocyclization to close the carbon backbone of fusaric acid (By similarity). Dihydrofusaric acid is likely to be released via reduction by the thioester reductase (TR) domain of FUB8 whereupon the final oxidation to fusaric acid may (also) be performed by the FMN-dependent dehydrogenase FUB9 (By similarity)."}]}
+{"id": "function_test_1441", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAGKPPVLGLAFPARLRGGVLWKAIRAEAAGHVEREWFGSGPHRLKIALPRPEGLSARPHDPRPVDPAHGQKILSGALTLDGGALRLGVDGDPFDTASPSRRFAVSLHRFDWLPDLVAVGPDGARRALRLIDDWRRVFGKWNAFSWGPECLERRVHHLACAAKTLAAEASDAEVADLVFDLARQGRHLLEITRAPERTLERAVAAGLAGCVLAGKPGEPLIDAALKALVPQLDAMVLGDGGHATRSPEAGVELLFDLLTLDDALGQRGRPSPEALSRAIDRLSSATRFFILGDGHLAAFHGGETVGPARIAAALAHDDAGPRSLNAAPHSGYHKMIGGSIEVIADCGPPPVGPLSVNACAQPAAFEIVCAKDRLITSCGWSPEAAGAHAFRLSDAASTVSVADGSAGRPLSGFRAKALGPWLVDGAAKVEAKRHDDVGGVWLDIVHDGWRHLGLTHARRLFLDAVQDELRGEDSLSPLALDPKAAEGPRRYLPFAVRFHLHPDARASIARDGKSVLIRGPSNIGWWLRNDAVDVEIAPSAHFDHGLARKAGQIVLKSQVRPEVGAKIRWKLTKAEG", "output": "Membrane anchor for FtsZ. Binds and recruits FtsZ polymers to membranes early in the cell cycle. May also improve the efficiency of cytokinesis through the regulation of cell wall hydrolysis."}]}
+{"id": "function_test_1442", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKRPVDFYAMKESGEKITMITAYDYPSAKNVEQAAADMILVGDSLGMVVLGYDSTVPVTIDDMIHHTKAVKRGAPNTFVVTDMPFMTYHGSVDETIQNARQIIQESGAHAVKLEGAGEVVNKIARLTEAGAPVVAHLGLTPQSVGLTGSYKVRAKSVQEAQELIDNALAVEAAGAIAIVLEAIPRQLAEKVTKALTIPTIGIGAGVETDGQVLVYHDIIGYGISRRAKFVKAYADIDETIEPALTSYVKEVKEQTFPEVKHSFTMAEEDLKGLYGRE", "output": "Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate."}]}
+{"id": "function_test_1443", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQDRFIKSITQLPTPLADALIPLLHQNFAGHIDAQQLAELVQSSKMTEAEVLLALLPIAAALAKPPISEFYVGAIAKGKSGDIYMGANLELLGEALFHSVHAEQSAISHAWLSGESQIVDMIVNASPCGHCRQFMNELVEGGQIKIHLPSQDSHLLSYYLPYAFGPKDLNVQSPLLVKQETEFALDSSDPMVIEALDHAGLSYAPYTQSYAAVVLETADGATYCGRYAENAAFNPSMLPMQMALSNLTRHNRDFGEIRRAVLVESSQGKISLVGATMDALHAVAAIELEHIVVDPV", "output": "This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis."}]}
+{"id": "function_test_1444", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLTSPLSPFEHEDSNLLLSAEQLTQYGAFWTAKEISQQPKMWRKVSEQHSDNRTIAAWLTPILAKPQLRIILTGAGTSAYIGDVLAAHIQQHLPLATQQVEAISTTDIVSHPELYLRGNIPTLLISYGRSGNSPESMAAVELAEQLVDDCYHLAITCNGQGKLANYCADKSHCYLYKLPDETHDVSFAMTSSFTCMYLATLLIFAPNSQALMQCIEMAEHILTERLADIRLQSEQPSKRVVFLGGGPLKAIAQEAALKYLELTAGQVVSAFESPLGFRHGPKSLVDSHTQVLVMMSSDPYTRQYDNDLIQELKRDNQALSVLTLSEELLTGSSGLNEVWLGLPFILWCQILAIYKAIQLKVSPDNPCPTGQVNRVVQGVNVYPFVK", "output": "Involved in the pathway of N-acetyl-D-galactosamine degradation. Catalyzes the conversion of D-galactosamine 6-phosphate (GalN-6-P) to D-tagatofuranose 6-phosphate (Tag-6-P). It can also catalyze the conversion of D-glucosamine 6-phosphate."}]}
+{"id": "function_test_1445", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKASLADARLYLCVDSRRRQGDLPAFLDAVLGAGVDVVQLREKGLEAKEELRLLDVFAEACRRHGALLAVNDRADIAYAARSDVLHLGQDDLPVGIARSIVGDDVVIGLSTHSVEQVQAAVSDPAVDYFCVGPCWPTPTKPGRPAAGLDVVRYAAQAAGDRPWFAIGGINLQNLDEVLEAGARRVVVVRAIADAPDPAEAAAEFAARLAAAA", "output": "Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)."}]}
+{"id": "function_test_1446", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPELPEVETIRRGLARHLVGRRIGYAEVFHPRAVRRHSGGAADFTGRLIGRRIQAVLRRGKYLWFALDSDLALLAHLGMSGQFLLADAASPSPKHLRARFAFTDGDPELRFVDQRTFGGLTLAPLIADVPASISHIAPDILDVAFDEAEFHRRFTQRRTGVKRALLDQTLISGVGNIYADEALWRARLHYATPTVDISAATCRRLLAALRAVFRAALRAGGTSFDALYVNVNGQSGFFDRSLAVYGRAGQPCRRCGTAIVREPFMNRSSFRCPACQPVPRRPHW", "output": "Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates."}]}
+{"id": "function_test_1447", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSTFIGQLVGFAAIVFLVWRYVVPPVRRMMAARQDTVRQQLADAATAAVRLTESTTAHSKAVEAAKAEAEQVVAEAKEEAKRITAQMQTQAGVEAERIKVQGSRQVELLRTQLTRQLRLELGHESVRQASELVRNHVSDPGQQAATVDRFLDELDAMAPAAAEVERPVAAKMRSASRRALGSLVDKFAGLAKGLDNAALSALASGLVSVAQLLQREVIVTRYLTVPAEDAAPRIRLLERLISGQVGNPALDILRAAVTERWSASSDLIDAIEHVSRQALLEVAQRDGQVDEVEDQLFRFSRILDAQPRLSILLGDYVVPAEGRVGLLRKVLDSAGSVNPIAVALLSQTVELLRGQPAEEAALLLAEVAVARRGEVVAQVSAAAELSDAQRTRVTEVLSRIYGHPVTVQLQTDPTLLGGLSIAVGDEVIDGTLSSRLTAAEAQLPD", "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity).; "}]}
+{"id": "function_test_1448", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MYTKDTIVAIATPQGNGGIGIIRISGIDALAIAEKLTKKQLKPRYATFCNVYNDNEIIDHGIVIFFKAPLSYTGEDVVEIQAHGNPFILNLIIKAALNCGARMAKAGEFTERAFLNNKLDLTQAEAVADIINASSEIAAKSAAKSLQGDFSKEINNLLEKLIYLRMYVEASIDFPEEEINFLEDQKIHSSLEEIYKVILAVKNSCKQGVILAEGITLILVGKPNAGKSSLLNALAGKESAIVTSIAGTTRDIVKEHIQINGVPMHIIDTAGLRNSDDIIESEGIKRAIKKIQEADQVLFVTDDYTNSQVKFSDIKEIIPEFYDQIPKDIDITYVHNKIDLLKEVPHNHANHIYISAENNIGIDKLKEHILNKVGYTNQNESIYTARERHVTAINNAFEHIKLAKEQLELGNGELLAEELLIVQEYLNSITGEFSSDDLLGEIFSSFCIGK", "output": "Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34."}]}
+{"id": "function_test_1449", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAEKLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA", "output": "Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP."}]}
+{"id": "function_test_1450", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNLDYLDFEQPIVELEEKIQALDNIKDKADIVDEMGALKIKSNALTKKIFSSLSDWQISQLARHPKRLYTLDYISHVFDEFTELHGDRIYGDDHAIIGGIARLDAQPVMFIGQQKGRTTQEKLKYNFGMPRPEGYRKALRLMKLSEKFSMPIITFIDTPGAYPGIGAEERGQSEAIAKNLFEMSTLATPIISVVIGEGGSGGALAIGVADIIMMFKYSIYSVISPEGCASILYKDATKANLAAESLKLTSAHLKENGLIDIIIDEPLGGIHRDPSQAKVLLKEALIQQLNEIKQLPIEQLLQNRQEKLLNFGKFKD", "output": "Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA."}]}
+{"id": "function_test_1451", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLGKMILLPLFVLLCHSLASASLAYRGADISSLLIEEKAGIKYKDVNGQAQPLENILKANGVNSVRQRVWVNPSDGSYNLDYNVKLAKRVKAAGMSVYLDLHFSDTWADPSHQTTPRGWSTNDIGTLTWQVYNYTKEVCDTFASNGIDVSIVAIGNEIRNGLLWPLGKPNNYANIANILHSAAFGVKDSTLSPKPKIMIHLDNGWDWSAQKFFYDSVLSSGAKLVKSDFDLIGVSYYPFYNPSATLSALTTSLKNLRSTYGKDVLVVETDWPVSCPNPAYAFPSDLKDIPFSVAGQKTFVQRVANVVAQTPGGIGLYYWEPAWVQNAALGSSCADNLMVDWRTDQARTSLSVFGTI", "output": "Endogalactanase involved in the degradation of plant cell wall polysaccharides, and more particularly of hairy regions of pectin."}]}
+{"id": "function_test_1452", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNDTQNPLHGAEASPLGKPVAYRDTYAPELLFPIARQLKRDEIGVRADALPFCGEDLWNAYELSWLNPRGKPVVALAEFRVPADTPRLVESKSLKLYLNSFNQSRFDDAAAVRMAIARDLSAAAGGAVGVAVWPLGGQAERRFAAPEGVCIDDLDVAIDTYQPDPTLLSAGDEVVSETLYSHLLKTNCLVTGQPDWGMVAVRYTGPRIDRAGLLRYIVSFREHNEFHEQCVERVFCDITARCRPQRLAVWARYTRRGGLDINPFRASDRDQRADEAMEIRQ", "output": "Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)."}]}
+{"id": "function_test_1453", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPSEHPFSDGISTPNPKETMNDTAQITASYGRRYIVRTPDGTTYEASTRKKRVDFACGDRVRISPVNAEQVVIEDFLPRQSLLYRQDAWKTKLIAANVTQLLIVTAAVPSPSMRLLQRALLAAEAAGIEAVIVLNKADLPETALWREKLKFYETLGYPVIETRALENADLLRPVLQGHSNILLGQSGMGKSTLTNALLGSQTARTGDISAALDSGKHTTTHARLYDLNGETQLIDSPGLQEFGLHHLQAADLPRYFPDFRHLVGQCRFHNCTHRAEPGCAFKAAAETGAASPERLAFLQGITDELPG", "output": "One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit."}]}
+{"id": "function_test_1454", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAAKATGGGAPLRSQQPQKSPKSLTVRQKKILETIQRSVNDNGYPPSMREIGDTVGLASLSSVTHQLSQLEKLGYLRRDPKRPRAMEVLMPLTLDGGAIPGVEAPTTLRSAGGLAVTELASASDTAMVPLVGRIAAGGPILADQTVEDVLALPRQLVGHGELFMLKVAGDSMIDAAICDGDWVVVRRQNDAINGDIVAALLDDEATVKTFRQRDGHTWLLPQNTQYEPILGDQATIMGKVVSVLRSL", "output": "Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair."}]}
+{"id": "function_test_1455", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSVPDVAVVKAFLIDLQNRICAGLQALDGQATFAADSWTRAEGGGGTSRVLTQGAVFEQAGVNFSHVTGAAMPASATAHRPELAGRSFEAMGVSLVIHPNNPYIPTTHANVRFFIAQKEGADPVWWFGGGFDLTPYYPFEEDVREWHQTSKDICAPFGDEVYPKYKKWCDEYFFLPHRNETRGVGGLFFDDLNQDGFEQSFSFMQAVGNGFLTAYAPIVERRKETEFGERERQFQLYRRGRYVEFNLVYDRGTLFGLQTGGRTESILMSMPPLVRWQYAYTPEAGSPEADLYDNYLKPRDWV", "output": "Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX."}]}
+{"id": "function_test_1456", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLFGMRALKVLGIESTAHTFGVGIATSSGDILVNVNHTYVPRHGGIKPTEAAEHHSRVAPKVLSEALQKAGISVEEVDAVAVALGPGMGPCLRVGATLARYLALKFGKPLVPVNHAIAHLEISRLTTGLEDPVFVYVAGGNTMVTTFNEGRYRVFGETLDIPLGNCLDTFAREVGLGFPGVPRVEELALKGREYIPLPYTVKGQDVSYSGLLTHALSLYRSGRARLEDVCYSLVETAYSMLVEVAERALAHTGKSQLVLTGGVARSRILLEKLRRMVEDRGGVLGVVPPEYAGDNGAMIAYTGALAFSHGVRVPVEESRIQPYWRVDEVVIPWRSR", "output": "Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37."}]}
+{"id": "function_test_1457", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTRVSLSPLAWLDEVETQRRAAGLRRTVRTRPPVGAELDLASNDYLGLSQHPRVIDGGVSALRTWGAGSTGSRLVTGNTELHEAFEDVLAAFVGAESALVFSSGYTANLGAVVALSGPGSLLVSDANTHASLVDACRLSRARVVVTPHNDTAAVEQALATRSEARAVVVTDSVFSADGDLAPLRALHTACRKHGALLIVDEAHGLGVRGDGGRGLLDEVGLAGAPDLVMTTTLSKALGSQGGVVLGPAAVRAHLIDTARPFIFDTGLAPAAVGAAFAALQVLIDEPWRAQRVLDHAATLASICDVTEVPSSAVVSVILGEPEVAFAAAAACLDRGVRVGCFRPPTVPAGTSRLRLTARASLSEDEMTLARRVLTEVLSPR", "output": "Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide."}]}
+{"id": "function_test_1458", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNTPDQSQLGRVSGYADQYDASLLFPLPRQPKRHEIGVTGTPPFFGADLWTAFELSWLNLRGKPQVALAHITVPCETPNIIESKSFKLYLNSFNNTRFADAAQVQTRIRTDISEAAWRGSDRQATVGVKLVLPEMFDREPVQELDGLLLDRLDVECTHYTPAPELLHANHGEAPVTETLTSHLLKSNCLVTGQPDWGSVRIEYSGAQIDQSGLLRYLVSFRNHNEFHEQCVERIFMDLWTRCRPIKLSVYARYTRRGGLDINPLRTSHPQALPANVRTARQ", "output": "Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)."}]}
+{"id": "function_test_1459", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKHIPRKRFGQHFLSDQGIIDAIVRAIAPEPGQPMVEIGPGLAALTQPLVERLGRLTVVELDRDLAARLRQHGQLDVIESDVLKVDFAQVAQALNASKIRVVGNLPYNISTPILFHLLAHVRVIADQHFMLQKEVIDRMVAAPATSAYGRLSVMLQWRYAMENVLFVPPESFDPPPRVDSAVVRMVPHEAPEALSMPVLEELVQVAFSQRRKLLRHTLGRWLEARQFAGTFDTQRRAEEVPVSEYVALAQECS", "output": "Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits."}]}
+{"id": "function_test_1460", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MMTKVLGMAPVLGPRPPQEQVGPLMVKVEEKEEKGKYLPSLEMFRQRFRQFGYHDTPGPREALSQLRVLCCEWLRPEIHTKEQILELLVLEQFLTILPQELQAWVQEHCPESAEEAVTLLEDLERELDEPGHQVSTPPNEQKPVWEKISSSGTAKESPSSMQPQPLETSHNYESWGPLYIQESGEEQEFAQDPRKVRDCRLSTQHEESADEQKGSEAEGLKEDIISVIIANKPEASLERQCVNLENEKGTKPPLQEAGSKKGRESVPTKPTPGERRYICAECGKAFSNSSNLTKHRRTHTGEKPYVCTKCGKAFSHSSNLTLHYRTHLVDRPYDCKCGKAFGQSSDLLKHQRMHTEEAPYQCKDCGKAFSGKGSLIRHYRIHTGEKPYQCNECGKSFSQHAGLSSHQRLHTGEKPYKCKECGKAFNHSSNFNKHHRIHTGEKPYWCHHCGKTFCSKSNLSKHQRVHTGEGEAP", "output": "Strong transcriptional activator (By similarity). Plays an important role in spermatogenesis; essential for the progression of meiotic prophase I in spermatocytes (By similarity)."}]}
+{"id": "function_test_1461", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNILIIFTSYLLGSLPTGFLIGKYLKNIDLRTIGSGSTGATNVLRNVGKWPALFVFIIDVGKGLIAVKIAQYYTDQGLIEVIAGISAISGHIWPIWLRGKGGKAVATGLGMFLALSWKVGLASLGIFLIVLTKTKFVSLSSISAAILLPIFMFFYLGKFIHSYFFISLIVALLVIWKHRTNIKRLIKGEESKINQNQ", "output": "Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP."}]}
+{"id": "function_test_1462", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPNEIFTINLNAQAIIPEAFILLGIVGTLLVDLAGEKTASRWAPVICYISLGSSLVSLAFQWSNPVNNAFLGSFNSDNLAIAFRSIIALSTLISLLISWRYTEQSGSPIGEFAAIVLSATLGAMLLCGSTDLVSVFISLETLSVASYLLSGYLKRDPRSSEAALKYLLVGSAAAAIYLYGSSFLYGLSGSTNLSTIGVEIINKPSFITSLSLVFVLSTVAFKIAAVPFHQWTPDVYEGSPTPVVAFLSVGSKTAGFAFAIRILTTSFSSFDEQWKLLFTILAILSMALGNIVALAQTSMKRMLAYSSIGQAGFVMIGIVSGTQDGLSAAVLYLAAYLFMNLGAFSCVILFSLRTGSDRISDYSGLYQKDPLITLGLSLCLLSLGGLPPMLGFFGKIYLFFAGWANHQYLLVVVGLVTSVISIYYYISVIKMMVVKEPQEASEIVKSYPEIKWNIIGLPPLRIALYTCIAVTALGGILSNPLFKLANSAVSETPFLQDILAVTNNML", "output": "NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration."}]}
+{"id": "function_test_1463", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKRSMYAGRVREEHIGTTITLKGWVSRRRDLGGLIFIDLRDREGVMQLVINPEEVSSDVMATAERLRSEYVIEVEGFVEARQQANDKLATGMVELKVSALTILNTAKTTPFEIKDDAEVSDDTRLRYRYLDLRRPEMLENFKLRAKVTHSIRNYLDDLEFIDVETPMLTKSTPEGARDYLVPSRVSQGHFYALPQSPQITKQLLMNAGFDRYYQIVKCFRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKETKEIDVTLPFPRMSYDVAMNSYGSDKPDTRFEMLLQDLTVTVKGIDFKVFSEAPAVKAIVVKGNADRYSRKDIDKLTEFAKQFGAKGLAWVKVTDGQFSGPVAKFLTAIETELSSQLKLAENDLVLFVADTLEVANNTLGALRNRIAKDLDMIDQSQFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPTPESAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKEMQERMFKALGFTADEANDQFGFLLEAMDYGFPPHGGLAIGLDRFVMLLAEKDNIREVIAFPKNNKASDPMTQAPSLVSENQLEELSLQIESHD", "output": "Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)."}]}
+{"id": "function_test_1464", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MVKPDIHTLAHHLKQERLYVNSEKQLIQRLNADLLKTAERLYRTSWIAKQQRINLDRLILTSAEASPAECCQHAKVLEDTQFVDGYKQLGFQETAYGEFLNLLRENPRLIASCLVTGEKLNQENAQSVIHTVFTSLYGNCIMQEDESYLLQVLRYLIEFELKESDNPRRLLRKGTCAFSIIFKLFSEGLFSAKLFLTATLHEPIMQLLVEDEDHLETDPAKLIERFSPAQQEKLFGGKGTEAFRQRVQAMVETNEAKLVALVNKFIGYLKQNTYCFPHSLRWIVSQMFKTLSCVEGLEVSEVRSMCTDLLLTCFICPAIVNPEQYGIISDAPINEVARFNLMQVGRLLQQLALTGFEERDSRNKSNLNKFDKSCVAAFLDVVIGGRAVETPPLSSVNLLEGLSRTVVYMTYSQLMSLLGFMRTVISSEQLQEEDRMALENLLATVPQTKPGKSNNDTPYSTPQLSPATTPACKKNRLPIVTRSRSKTNLMETENECSPQEVTPNQPEEVLVISLGTGPQLTPGMMSENEVLNMQLVDGGQGDVPVDESKLHGKPDKTLRFSLCSDNLEGISEEEENPCSTGPSNRSNSVSSLDLEGESVSELGGGPSGSNGVEALQLLEHEQATTQDNLDDKLRKFEIRDMMGLTDDRDISETVSETWSTDVLGSDFDPNIDEDRLQEIAGAAAENMLGSLLCLPGSLLLDPCTISETTSEAWSVEVLPSDSAPDLKQEERLHELESCSGLGSTSDDTEVREVSSRPSTPGLSVVSGISATSEDIPNKTEDLRSECSSDFGGKDSVTSPEAEESVHGPHHITTPPTQSESLLAMFDPLAPASSEVVRPKVHYARPSHPPPDPPVLEGASGGNEARLPMFCSHVFIHTDSEAYRQRHSCPERLVRSRSSDIASSIRRPISDPGWVRRGINEDRELLTGTAVNALINPPQSSSFSPSKDSSRGEPDEKKDSDDERSDRNKPWWKKRFVSAMPKAPIPFRKKEKQEKEREDFVQDRFYVAVDSTSQLGPHSQAAEDILAKYRNAIKRTIPNEGSTMPYEGADPVGDGESLHESPRDEALQNMTSDDLLDSANQVAHPQESAFSYRDAKKKLRLALCSADSVAFPVLSHSTRNGLPDHTDPEDNEIVCFLKVQLAEAINLQDKNLMAQIQETMRCVSRFDSRSCSKILSSLAEDYRKRASYIAYLTRCRQGLQSTQAHLDRLLQRVLRDKEVSTRYFTTVCVRLLLESKENEIHEFIQDFQKLTAADDKTAQVEEFLQSLYGAMAQDVIWQNASEEQLQDAQIAIERSIMNRIFKLAFNPNQDADILRDQVLHEHIKRLSKVVTANHRALQIPEVYLREAPWPSAQTEIRTISAYKTPRDKVQCILRMCSTIMNLLSLANEYSVPGADDFVPVLVFVLIKANPTYLLSTVQYISSFYSNRLIGEESYWWMQFTAAVEFIKTIDDRK", "output": "Acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF), and participates in various processes such as endocytosis, insulin receptor internalization or LC2A4/GLUT4 trafficking."}]}
+{"id": "function_test_1465", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MERTTIMTLDFSKPGEAGYQSGFANEFATEALPGALPHARNSPQRAPYGLYAEQFSGTAFTAPRGHNRRSWLYRIRPAAVHRPFELVSGERRIVAEFGDSDDVPPTPPNQLRWDPLPMPAQPTDFVDGWVTMAGNGSAAAMSGCAIHLYAANRSMRERFFYSADGELLIVPQEGRLFIMTELGRLDVEPFEIAVIPRGVRFAVALPDGRARGYVCENFGALLRLPDLGPIGSNGLANPRDFLTPHASYEDREGAFELVAKLNGRLWRADIDHSPFDVVAWHGNYAPYKYDLRHFNTIGSISYDHPDPSIFLVLQSQSDTPGVDAIDFVIFPPRWLAAEDTFRPPWFHRNVASEFMGLVHGVYDAKAEGFVPGGASLHNCMSGHGPDADTFEKASSIDTSKPNKVGDTMAFMFETRTLIRPTRFALDTAQLQANYFECWQGLKKHFNPEQR", "output": "Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate."}]}
+{"id": "function_test_1466", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSASVAEPPPALSRKAEFKAAKAELLARFKSANHVTPLMHALSRATDDALRSLWQECGLPATLALVAVGGFGRGELSPHSDVDILVLLPDAHASELDERIERFIGMAWDLGLEIGSSVRTVDQCIEEASHDVTVQTSLLEARRIVGSTALFERFMLRYREALDARAFFQAKVLEMRQRHAKFQDTPYSLEPNVKESPGGLRDLQTILWIARAAGFGSSWRELDTRGLITDREARELRRNEGFLKTLRARLHVIAGRRQDILVFDLQTQAAESFGYQPTSAKRASEQLMRRYYWAAKAVTQLATILIQNIEAQLFPATSGVTRVLSPGRFVEKQGMLEIAADDVFERHPDAILEAFLLYEATRGVKGLSARTLRALYNSRDVMNNAWRRDPRNRHTFMQILQQPEGITHAFRLMNQTSVLGRYLLNFRRIVGQMQHDLYHVYTVDQHILMVLRNIRRFAVAEHAHEYPFCSQLIVNFERPWVLYVAALFHDIAKGRGGDHSALGMADARRFCREHGIEGDDAALVVWLVQHHLTMSQVAQKQDTSDPVVIKRFAELVGSERRLTALYLLTVADIRGTSPKVWNTWKGKLLEDLYRATLAVLGGAQPDAHSELKTRQEEALALLRLETVPPDAHRALWDQLDVGYFLRHDAADIAWQTRVLYRHVAADTAIVRARPSPVGDALQVLVYVKDRSDLFAGICAYFDRNGLSVLDARVNTTRHGYALDNFIVTQTEHDVQYRDIANLVEQQLAARLAESAPLPEPSKGRLSRLSRTFPITPRVDLRADERGQYYILSVSANDRPGLLYSIARVLAEHRVGVHAARINTLGERVEDVFMLDGTGLSDNRLQIQVETELLRAIAV", "output": "Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism."}]}
+{"id": "function_test_1467", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIALLQRVSQARVEVGGRRVGEIGPGLLVLVCAEPSDTGAVADKLVERLLKLRVFSDDAGKMNRSVVEAGGGLLIVSQFTLAADCSGGNRPSFSGAAPAEQGRVLYERLLATARSRHTPVECGEFGADMQVLLVNDGPVTIPLVVGHDKLRP", "output": "An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality."}]}
+{"id": "function_test_1468", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRPSNRTPAQTRPITITRQFTAHAEGSVLVEFGETKVLCTASFTEGVPRFLKGQGQGWVTAEYGMLPRSTHSRMDREAARGKQSGRTQEIQRLIGRALRACVDMKALGENTIVIDCDVIQADGGTRTASITGACVALVDALNWARGKGIIKSNPLKFLIAAVSVGIYKGEAISDLEYIEDSAAETDMNVVMTETGKIIEIQGTAEGEPFSHEELLELLALAKNSIREIVDVQKAALN", "output": "Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation."}]}
+{"id": "function_test_1469", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPTLFALKERIAQVVQEKNDPIVTAVATTLAEQQYNACFSAEQVKLWKRQFKCSSVELALACLPIAACYALVPISNFYVGAVAIGESGRFYFGANQEFNAQAIQQTVHAEQSAISHAWLAGETAITDMVVNYTPCGHCRQFMNELNSAKTLKIHLPHSQNNLLRQYLPDSFGPKDLNIEKVLFDQQTHSLPLRGDLLTQAAIQTAAQSYAPYSKSLSGIALQVGEQIICGRYAENAAFNPSFLPLQSALNYRRLSGKSDERISRIVMAESKGTTSHRQMSEALAESFLGLNLEYIEV", "output": "This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis."}]}
+{"id": "function_test_1470", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQVTETQKEGLKRAYTITVTAAELDAKVQEKLVEAQPDIEMKGFRKGKVPLAMLKKQFGPRLLGDAMQDAIDGAMRDHLETSGDRPAMQPEVRMVDGETWKEGTDVVVEMKYEALPEIPEIETSKVSLERLVVKADEAAIEEALKNLAESAQNFEDRRKGSKAKDGDQVVIDFKGSVDGELFEGGSAEDYPLVLGSGSFIPGFEEQLVGTKVDDEVTVKVSFPAEYGAKHLAGKEAEFACTVKAVKAPKAAELDDELAKKYGAEDLAALKSQISERLEAEYKGASRAVLKRALLDQLDQMVSFELPSKLVEAEAHQIAHQLWHEEHPEEHGHNHGNIEPTDEHKALAERRVRLGLLLAEIGRKAEVTVTDAEMTQAVLAQARQYPGQERAYFEFVQKNPQIQQQLRAPIFEDKVVDLILEGATVTEKEVGKDDLQKAIEALDEM", "output": "Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase."}]}
+{"id": "function_test_1471", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTIRLLGRTEIRRLAKDIDFRPRKSFGQNFVHDANTVRRIVSASGVHRHDHVLEVGPGLGSLTLALLDRGAHVTAVEIDPLLAQQLPTTIADHSHSEINRLTVLNQDILTLMPSDLENQPTALVANLPYNVAVPALLHLLAEFPTIRSVMVMVQAEVAERLAADPGGKDYGVPSAKVRFYGNVRRYGMVSPTVFWPIPRVYSGLVRIDRYETSPWPTDADFRAQVFDLIDIAFAQRRKTSRNAFAEWAGSGNESARRLLAASIDPSRRGETLAIADFVRLLQRSGEAEEQVRVQ", "output": "Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits."}]}
+{"id": "function_test_1472", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MVPTPITVRVPAKVNLHLSVGDTREDGYHELVTVFQALSMTDEVTVHIADEPGIEVRGEGADSVPTGPSNLAWKAVRALAERCGRDPDEPGVRVSINKGIPVAGGMAGGSADAAAALLALNHLWRLEMGRDELAGIAADIGSDVPFALQGGTALGTGRGEQLIPVLARHTFHWVIALDRRGLETPGVFSELDRLREESRPNRVGEVEPVLEALASGDPRQLALLLGNDLQAAAVSLRPGLRRTLRAGVQAGALAGIVSGSGPTCAFLCTDADAAVRVAAELSGAGVCRTVRVAQGPVPGARLVTDDRADRPTPPQVHA", "output": "Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol."}]}
+{"id": "function_test_1473", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKPKTIIEKIWENHVVYREEGKPDLLYIDLHLVHEVTSPQAFEGLRQNGRKVRRPDLTFATMDHNVPTVNRFVITDEVARNQIAALERNCREFGIPLADLHSEEQGIVHVIGPELGLTQPGKTIVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLWQHKPKTLQIRINGQLGKGVTAKDVILAIIGRYGVGVGTGYIIEFTGEAIRRMSMEERMTICNMSIEAGARAGLISPDETTFAYLRGRKYAPKGEEFDQAVERWRALASDEGAEYDKTIEIDASTIAPMVTWGTNPSMSTSVDGTVPDPEQFESETERNAVRRALEYMGLKPGMSITEIPVQHVFIGSCTNSRISDLREAAKIVKGQKVAPGVRALVVPGSQQVKKQAEEEGLAQIFLDAGFEWRDAGCSACLGMNPDIIPEGEHCASTSNRNFEGRQGKGARTHLVSPAMAAAAAIYGRFVDVRQLEAEPVR", "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."}]}
+{"id": "function_test_1474", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKLRKGAKISIVGTGLVGASAAFAIMASGLASDLVLIDINKAKAEGEAMDLGDAAAFVKPLDVYAGSFEDCKDSDIIVFTAGANQKPGETRLDLVYKNVNILKESLPQLLKYCPYAIYLIVANPVDVLTHVALKISGLPSNQVFGSGTVLDTSRFRAELAEYCNVDPRNVHAYILGEHGDSEVAIWSTADVSGIPLKEFFQLRGIPPISREKVVKRVRNAAYEIIQLKGATYYAIAFTIKRICETVLRDENSILTVSGIVNDLYGIQDCCLSLPTIVNGAGREQVLPITLEREEEVALKNSAQILRDVIKQAGL", "output": "Catalyzes the conversion of lactate to pyruvate."}]}
+{"id": "function_test_1475", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVREKVKVSTRTLQWKCVESRKDSKRLYYGRFILSPLMKGQADTIGIAMRRALLGEIEGTCITRAKSENIPHDYSNIVGIQESVHEILMNLNEIVLRSNLYGTRNALICVQGPGYITAQDIILPPSVEIIDNTQHIATLTEPIDLCIELKIERNRGYSLKMSNNFEDRSYPIDAVFMPVQNANHSIHSYGNGNEKQEILFLEIWTNGSLTPKEALHEASRNLINLFIPFLHVEEETFYLENNQHQVTLPLFPFHNRLVNLRKKKKELAFQYIFIDQLELPPRIYNCLKKSNIHTLLDLLNNSQEDLIKIEHFHMEDVKKILDILEKK", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_1476", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MQVTETLKEGLKRAYTITVTAAELDAKVQEKLVEAQPDIEMKGFRKGKVPLAMLRKQFGPRLLGDAMQDAIDGAMRDHLETSGDRPAMQPEVRMVDGETWQEGTDVVVEMKYEALPEIPEIETSKVTLERLVVKADEAAVDEALKNLAESAQNFDDRRKGSKAKDGDQIVIDFKGSVDGELFEGGSAEDYPLVLGSGSFIPGFEEQLVGAKVEDEVTVKVTFPTEYGAKHLAGKEAEFACTVKAVKAPKPAEIDDELAKKYGAEDLAALKAQIAERLEAEYKGASRAVLKRALLDQLDTMVSFELPSKLVEAEAHQIAHQLWHEEHPEEHGHNHGTIEPTDEHKALAERRVRLGLLLAEIGRKAEVTVTDAEMTQAVLAQARQYPGQERAYFEFVQKNPQIQQQLRAPIFEDKVVDLILEGATVTEKEVGKDDLQKAIEALDEM", "output": "Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase."}]}
+{"id": "function_test_1477", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSESRKLFIKTYGCQMNVYDSERMAEALGAKGYVLTEVAEEADMVLLNTCHIREKAAEKVYSDLGRLRPLKVARPDLKIGVAGCVAQAEGEEILRRMPLVDLVVGPQSYHRLPDMLERTEGGARVIDTDFPEEDKFEHLPERKALRGPTAFLTVQEGCDKFCAFCVVPYTRGAEVSRPFARLMAEARALVEKGVREITLLGQNVNAWSNDGRGLGGLIRELARIDGLERLRYTTSHPNDMADDLIEAHGQEPKLMPYLHLPVQSGSDRILKAMNRKHAAEQYLRLVERIRAARPDILLTSDFIVGFPGETDADFEATLALIRAVGFGSAFSFKYSARPGTPAAEKPELPAELCDARLQTLQALLGEQQRAAQAAMVGRELGVLYEKAGRLPGQMVGKSDYLHAVHVEDPGARPGDLVRVRITASGPNSLAGERIGV", "output": "Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine."}]}
+{"id": "function_test_1478", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKVYYDKDCDLSIIQGKKVAIIGYGSQGHAQACNLKDSGVDVTIGLRKGSATVAKAEAHGLKVTDVASAVAAADLVMILTPDEFQGQLYKNEIEPNIKKGATLAFSHGFAIHYNQVVPRADLDVIMIAPKAPGHTVRTEFVKGGGIPDLIAVYQDASGNAKNVALSYASGVGGGRTGIIETTFKDETETDLFGEQAVLCGGTVELVKAGFETLVEAGYAPEMAYFECLHELKLIVDLMYEGGIANMNYSISNNAEYGEYVTGPEVINAESRQAMRNALKRIQDGEYAKMFISEGATGYPSMTAKRRNNAAHGIEVIGEQLRAMMPWIAANKIVDKTKN", "output": "Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate."}]}
+{"id": "function_test_1479", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MHDIKSIRDNPQGFDAALTRRGLSPQSSHLLAIDERRRAAILASEQAQARRNAASKEIGEAKKAKDDARASALMEEVAKLKTTMPELEAAAKQADEELARELSAIPNLPLDEVPDGKDEHDNVERHVFGARRNYAFAPRPHDEIGAALGMDFESAAKLSGARFVVLKKGLARLERAIGQFMLDLHTTEHGYTEINPPLLVRNDVMFGTGQLPKFEDDQFWAVRGELLIAPDERLKTERLGLIPTAEVALTNLVRESIVDEKELPMRLTALTPCFRAEAGAAGRDTRGMIRQHQFTKVELVSITTPETSKDEHERMLACAEEVLRRLDLHYRVITLCTGDMGFSSQKTYDIEVWMPGQGDGGAFREISSCSVCGDFQARRMDARYRASDGKPRFVHTLNGSGTAVGRALIAVMETYQQADGSIAVPDVLQPYMGGLKVVAAEP", "output": "Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)."}]}
+{"id": "function_test_1480", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MANPKADRLIQFLTEQGITSPQVLAAIHALPREFFVAPAMMHQAYDNNALPIGQGQTISQPYIVAKMTELLALTPETKVLEIGTGSGYQTAVLAKLVNHVFTVERIKTLQWDAKRRLKQLDIYNVSTKHGDGWQGWPARGPFDAILVTAAAAKVPQSLLDQLAEGGRMVIPVGEDEQYLYKIVRQGGQFISERVEAVRFVPLVAGDLA", "output": "Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins."}]}
+{"id": "function_test_1481", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAAGSTGERPFFEIITSIRYWVIHAITLPSIFLAGFLFVSTGLAYDAFGTPRPDAYFQATESKAPVVSQRYEGKSQLDDRLQ", "output": "This b-type cytochrome is tightly associated with the reaction center of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation."}]}
+{"id": "function_test_1482", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRVKYFGTDGIRGVFGETLTDELAFKVGKALGEIVGEGRVIVGKDTRVSGDSLEAAISAGLTSMGVDVLLCGVLPTPAVALLTRITRSFGVVISASHNPPEYNGIKVLKGGYKIPDEMEVKIEEKIESGYFPVRSVVGRTKSFREGRDMYIGAVLEIFRDLDLTGEMVSLDLANGATTTTAKEVFEFLGAKVEVFNDSQDGLLINQGCGATHPRFLAEEMKNGKVGFTFDGDGDRVIAVDEERNVVNGDRIIGILAVGLKEEGRLNSDTVVGTVMTNGGLEDFLKERGIKLLRTKVGDKYVLEKMIESGANLGGERSGHIIILDRSTTGDGLITALELMRVLRRSGRNLSDFAKEIPDYPQITKNVRRTERMSLENENLRKIVEESTSRGYRVVIRPSGTEPVVRITVEGKDREEIEKIVEEISRVLES", "output": "Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate."}]}
+{"id": "function_test_1483", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKLHEYQARDILARYGIPVTGGGVATTPAEARTIAEQIGGRVVVKAQVFVGGRGKAGGVKLADTPEQAEQVASQILGMNIKGLTVEKVLVAEAITYEREIYLGAIMDRASRRIVMMASAEGGVEIEEVARTNPEAIVKVAAHPMMGLLDFQARDLAYGIGLTDGRQARQFAQIATALYRAYMDVDASLAEINPLVVRADGSLQALDSKIVLDDSGLFRHPDLEAMRDSSDEPEAEQRAREAGITYIKLDGNIGCMVNGAGLAMATMDVVKLYGGEPANFLDIGGGAGKEKVKTALQIILSDPNVKAVMFNIFGGITRVDEVAKGIIAALEEVNTDVPMIARLVGTNEEEGRRILAESALIPAATLAEAAEKAVQAAQSR", "output": "Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit."}]}
+{"id": "function_test_1484", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MILAANFKMNHTRASTKAYIERLNAYGKQTDIDIAVFPPATALDQYETFADIGAQNAYAAEHGSFTGEIGLQQLQEFGIETVLLGHSERRHIFYESQEMIARKFAFYKERGFTIYYCLGETLQTRKKGFEAIRELLQSQLEGIDTAYENFVIAYEPVWAIGTGVAAKPEEIEEVLAYLASLTDAPLLYGGSVKPANIKEVLSIPKCDGALIGTASWDVENFIKMIEIAKEMR", "output": "Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)."}]}
+{"id": "function_test_1485", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MASNDKGLEEIPEGQIESNYDEITDSFDAMNLRAELLRGVYAYGFERPSAIQQRAIMPVIKGSDVIAQAQSGTGKTATFSISALQKVDTNLKACQALILAPTRELAQQIQKVVVAIGDFMSIECHACIGGISVREDMKALQDGPQVVVGTPGRVHDMIQRRVLKTDHMKMFVLDEADEMLSHGFTEQIYDIFQFLPQSTQVVLLSATMPQDVLEVTTKFMRDPVRILVKKAELTLEGIKQFYIAVEKEEWKLDTLSDLYETVTITQAVIFCNTRRKVDWLTDKLTARDFTVSAMHGDMEQQQRDVIMKEFRSGSSRVLIATDLLARGIDVQQVSLVINYDLPANRENYIHRIGRGGRFGRKGVAINFVTADDNGRTRKAKRKKGI", "output": "ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity)."}]}
+{"id": "function_test_1486", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MHNQAPIQRRKSKRIYVGNVPIGDGAPIAVQSMTNTRTTDVAATVNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLESAMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAVKSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGVRKDRLDNNDMIDQLEARIRAKASMLDEARRIDVQQVEAK", "output": "Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate."}]}
+{"id": "function_test_1487", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTKIAFTGGGTVGHVSVNLSLIPTALSQGYEALYIGSKNGIEREMIESQLPEIKYYPISSGKLRRYISLENAKDVFKVLKGILDARKVLKKEKPDLLFSKGGFVSVPVVIAAKSLNIPTIIHESDLTPGLANKIALKFAKKIYTTFEETLNYLPKEKADFIGATIREDLKNGNAHNGYQLTGFNENKKVLLVMGGSLGSKKLNSIIRENLDALLQQYQVIHLTGKGLKDAQVKKSGYIQYEFVKEDLTDLLAITDTVISRAGSNAIYEFLTLRIPMLLVPLGLDQSRGDQIDNANHFADKGYAKTIDEEQLTAQILLQELNEMEQERTRIINNMKSYEQSYTKEALFDKMIKDALN", "output": "Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II)."}]}
+{"id": "function_test_1488", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFREKLKRELQGIKDENLYRKLRNQDDFILNFSTNDYLGLSKNEEVILAYNEGLKDGAGSTGSRLTSGNFKLHEKLEGVISEFKETEKSLVYSSGYAANVGVISALAKKGDLVLSDELNHASIIDGIRLSRADKLIYRHSDVQNLIEILEKNKYYENIIVVTDSVFSMDGDVSPIDKIAKIIDEYNAVLIIDDAHGTGVLGQGKGTLKHFKVKASDNIIQIGTLSKAIGTSGGFVSGIEELIDYLINNSRSFIYSTSLPPAVISASIKSFELVEKERLSKNLEKNIICANKLFKNHGFIKCESITPIYPFVFGEKSIDISKGLINHGIFGVPIRYPTVKKGMERIRISITSKHEKNDFKYLCEKIDKLTI", "output": "Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide."}]}
+{"id": "function_test_1489", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKVVEVKHPLVRHKIGLMREGDISTKRFRELAAEVGSLLTYEATADFETETVTIEGWNGPVEVDQIKGKKVTVVPILRAGLGMMDGVLEHIPSARISVVGIYRDEETLEPVPYFEKLASDMNERIALVVDPMLATGGSMIATVDLLKKRGCTSIKALVLVAAPEGIKALEAAHPDIELYTAAIDKCLNEKGYILPGLGDAGDKIFGTK", "output": "Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate."}]}
+{"id": "function_test_1490", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRIILLGAPGAGKGTQAQFIMEQYGIPQISTGDMLRAAVKAGTPLGLEAKKVMDAGQLVSDDLIIGLVKERIAQEDCVKGFLLDGFPRTIPQADAMAANGISIDHVIEIDVPDEEIVKRMSGRRVHPGSGRVYHVVFNPPKVEGKDDVTGEDLAIRPDDEESTVRKRLAIYHEQTKPLVEYYGKVAAAGQTQYNKFDGTQSVAAVSEQLASVLK", "output": "Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism."}]}
+{"id": "function_test_1491", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIYYLIALFVIAIDQLSKWFIVKNMELGASIPIIDNVLYITSHRNRGAAWGILENKMWFFYIITVVFVGFIVFYMKKYAKTDKLLGISLGLILGGAIGNFIDRVFRQEVVDFIHVYIFSYNYPVFNIADSALCIGVVLIIIQTLLEGKKMKE", "output": "This protein specifically catalyzes the removal of signal peptides from prolipoproteins."}]}
+{"id": "function_test_1492", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKDITLVLLAAGDSTRFKAPFKKQWIRIGEIPLWQYVAKDLSQKCDFSDIIIVANEKEISYMKKIERNFKYAKGGKLRQNSLANALKKVKSEFVFVSDTARAEISKDLIGRLINECEKFDCVSPFLGVVDTTYLGRNQIDRNDLKLIQTPQISRANLLKKALESNEIFTDDSAAVAFAGGKLGFVEGDEKARKITFTSDLAHFDFTPASGTIFTGNGFDVHAFAKGEFITLGGVKIPCEYSLVGHSDADAAIHALMDAILGACGLGDIGELFPDTDDSFKGIDSKILLQKVVNFVHLLGFKIINADITIIAQKPKISPYKEKMCEILSEILQTSRVNVKASTTEKLGFVGRVEGVAAIASANLGYFDWRKF", "output": "Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)."}]}
+{"id": "function_test_1493", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKNAAMLSIGAYVPPYELSNFDLEKMVETSDEWIVKRTGIHTRHIAKNETAGDMAAKAADLAISRSGISKEEIDAIICATITPDFFCMPSTACITAEKLGLNKGITAFDISAACSGFIYLLEIGSALIKSGAKKNVLIIGTEKLSSIVDWKDRATCVLFGDGAGAAVLSCMDNKNNGISKPYGIIDIHTASDGNKAELLMTPTKNSNIKDIADENLGFLHMKGNEVFKIAVQTLSNDVVKILKKNNVKPEEIDLFVPHQANFRIIEAVKNRLNFTDNQCVVTVGKYGNTSSASIPIALNEAYENGRLKNGSLILLDAFGGGFTWGSALIRFGL", "output": "Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids."}]}
+{"id": "function_test_1494", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKALFASTARGLEELLKTELENLGAQECQVVQGGVHFQGDAALVYQSLMWSRLASRILLPLGECAVYSDLDLYLGVQAIDWTSIFAPDATFAVHFSGLNDTIRNSQYGAMKVKDAIVDAFTRKNLPRPSVDRELPDLRINVWLNKDTASIAIDLSGEGLHQRGYRDRTGQAPIKENLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMIATDRAPGLHRTHWGFNGWAQHDESLWKEVKTEAQVRARRGLSEYASRFYGSDNDARVIERARTNARRAGLADIITFAAQDVTNLTNPLPEGPTGTVISNPPYGERLESEPALIALHSLLGRIMKNQFGGWNLSLFSASPELLSCLQLRADRQFKAKNGPLDCVQKNYRLAPTQPGAAPAQIAEDYANRLRKNLKKLEKWAKQEGIECYRLYDADLPDYNVAVDRYADWVVIQEYAPPKTIEPEKARQRLFDVIAATLSVLGLAPNKLVLKTRERQKGKNQYEKLAQKGEFMEVHEFNARLLVNLTDYLDTGLFLDHRIARRMLGQMSKGKDFLNLFSYTGSASVHAGLGGARSTTTVDMSRTYLEWAERNLRLNGLSGRAHRLIQADCLSWLAESDEQFDLIFIDPPTFSNSKRMEETFDVQRDHLRLMKDLKRLLRRDGTIMFSNNKRGFKMDHEGLAALGLKAQDITQKTLSQDFARNRQIHNCWLVTHQTKD", "output": "Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA."}]}
+{"id": "function_test_1495", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSDLIQNVKTSFEQVLGYAPSHIIQAPGRVNLIGEHTDYNDGFVLPCAINYQTVVAAAKREDNLVRVVSVDYGNAVDEFDITQEITFQQDKMWANYIRGVVKCLLARGYQFSGADISVSGNVPQGAGLSSSAALEVVIGQTFKVLFNLEISQAEIALNGQQAENEFVGCNCGIMDQMISAEGRENHAMLLDCRSLETEAVSMPEDMAVVIINSNKKRGLVDSEYNTRREQCEEAARIFGVKALRDVTIEQFNEKVSELDEMVAKRARHVITENDRTVEAAQALRAHDMKRMGELMAESHASMRDDFEITVKEIDTLVEMVKEVIGEQGGVRMTGGGFGGCIVAIVPPALVDEVKATVEAKYQAATGLKESIYVCQAKNGAGLVEVL", "output": "Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)."}]}
+{"id": "function_test_1496", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIILGIDEAGRGPLSGPVVAAGVILDQDKIIDGLADSKKLTEKKRQSLYQQIITHAKAYTIVEISPQQIDELNILQATLKAIHQVANNLERQFDKVLVDGNKLPNWDYNSEAIVKGDSKIIEISAASILAKVHRDNICLEHDRLYPQYGFAKHKGYPTKEHLENIKKYGVLDIHRKSYKPVQVLLNE", "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."}]}
+{"id": "function_test_1497", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLHLTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS", "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage."}]}
+{"id": "function_test_1498", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLARMAGMTSGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFAMPVWHYLTLHQHDKTRTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANPAGQLLLLDEPMNSLDVAQQSALDKILSALCQQGLAIVMSSHDLNHTLRHAHRAWLLKGGKMLASGRREEVLTPPNLAQAYGMNFRRLDIEGHRMLISTI", "output": "Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system."}]}
+{"id": "function_test_1499", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGVRAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVAKEFNGDVQIELTGYWTWEQAQQWRDAGIQQVVYHRSRDAQAAGVAWGEADITAIKRLSDMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAASPVEAARQFKRSIAELWG", "output": "Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. Is involved in the anaerobic L-ascorbate utilization."}]}
+{"id": "function_test_1500", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLVIEDVRAYEVLDSRGNPTVKAEVTLSDGSVGAAIVPSGASTGSKEALELRDNDERFGGKGVLKAVANVNETIADEILGLDAFNQTQLDDTLRELDGTNNYSNLGANATLGVSMATARAAAAALGMPLYRYLGGANASILPVPMCNIINGGAHANNNVDFQEFMIMPFGFTSFKEALRSVCEIYAILKKELANSGHSTALGDEGGFAPNLANNTEPIDLLMTCIKKAGYENRVKIALDVASTEFFKDGKYHMEGKAFSSEDLIERYVELCAKYPICSIEDGLAENDFEGWIKLTEKLGNKIQLVGDDLFVTNEDILREGIIKKMANAVLIKPNQIGTITQTMRTVRLAQRNNYKCVMSHRSGESEDAFIADFAVALNTGQIKTGALARGERTAKYNRLLEIELESDEYLGEKL", "output": "Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis."}]}
+{"id": "function_test_1501", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSQVHKHAIPSAIAEHALINPTQYQQYYQQSVQDPETFWGEQGKILDWIKPYSRVKNTSFDPGHISIRWFEDGTLNLAANCLDRHLAERGDQTAIIWEGDDPTQSKQVTYKQLHHDVCQFANVLKKLGVKKGDVVAIYMPMVPEAAVAMLACARIGAVHSVIFGGFSPEAVAGRIIDSNSKLVITADEGLRAGRAVPLKKNVDDALKNPGVKSITNVVVFQRTGKPGYWQEGRDLWWHELTAGVSADCPPEEMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYAAMTFKYVFDYHDGDVYWCTADVGWVTGHSYLLYGPLACGAITLMFEGVPNYPGVNRLSQVIDKHQVNILYTAPTAIRALMAEGDKAIEGTKRDSLRIMGSVGEPINPEAWEWYYNKIGNAKCPIVDTWWQTETGGFMITPLPGATELKAGSATRPFFGVQPALVDNIGTVQEGACEGNLVITDSWPGQARTLFGDHDRFEQTYFSTFKGMYFSGDGARRDEDGYYWITGRVDDVLNVSGHRLGTAEIESALVSHPKIAEAAVVGIPHNIKGQAIYAYITLNHGEEPTPELYTEVRNWVRKEIGPIATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDTSNLGDTSTLADPAVVDKLLEEKQSMKVPS", "output": "Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.; "}]}
+{"id": "function_test_1502", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNNIIDGKALANEILADLKLEIQELTSQTNASPKLAIVLVGDNPASIIYVRHKIKNAHKVGIYTLLINLSATIHTNDLISKINELNLDNEISGIIVQLPLPSSIDKNKILSAISPSKDIDGFHPLNVGYLHSGISQGFIPCTALGCLAAIKKYEPNLTGKNVVIIGRSNIVGKPLSALLLKENCSVTICHSKTHNLRSITSKADIVVAAIGSPLKLTAEYFNPESIVIDVGINRISSNKIIGDVDFENVQSKVQYITPVPGGIGPMTIAFLLKNTVKAFKDSLYTLDT", "output": "Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate."}]}
+{"id": "function_test_1503", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPEVQLRNNWKREEIEALFALPMNDLLFQAHSIHRQEFDPNEVQVSRLLSIKTGACPEDCKYCPQSARYDTGLEKERLLAMETVLTEARSAKAAGASRFCMGAAWRNPKERDMPYLKTMVEEVKALGMETCMTLGMLSAEQANTLADAGLDYYNHNLDTSPEYYGDVITTRTYQSRLDTLTNVRASGMKVCSGGIVGMGEKATDRAGLIQQLANLEQHPDSVPINMLVKVEGTPFEKLDDLDPLEFVRTIAVARITMPKSRVRLSAGRENMSDELQAMCFFAGANSIFYGCKLLTTPNPEENDDMSLFKRLGLHPEQGIAATKEQDEAMLAKAAAHQDKKSAAFYDAGAL", "output": "Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism."}]}
+{"id": "function_test_1504", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSQLQESAVLSLAKDLISRPSVTPLDEGCQSLMAERLSQAGFEIESMVFDDTTNMWARRGTQSPVFCFAGHTDVVPVGDLNRWHTPPFEPVVIDDYLHGRGAADMKGSLAAMLVATERFVNKHPDHQGSIAFLITSDEEGPFINGTTRVIDTLEARNEKITWSLVGEPSSTHKLGDIVKNGRRGSLTGNLTVKGIQGHVAYPHLADNPIHKAAPALDELARMKWDNGNEFFPPTSFQIANINGGTGASNVIPGALEVMFNFRYSTEVTAEILIERVLNILDAHGLDYDISWVYNGLPFLTGEGPLLEATKAAIKKVTGTDTDPQTSGGTSDGRFIAPTGAQVIEVGPVNATIHKVNECVKVSDLELLTDCYEAILENLLCK", "output": "Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls."}]}
+{"id": "function_test_1505", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSGEGLVSAAAAPEEQAFEAGLRPKNLDEFVGQRKVREQLSIMLEGARGRGRPPDHVLLSGPPGLGKTSLAMIIAEELGVPLRMTSGPAIERAGDLVAILTALTPGEVLFLDEIHRIARPAEELLYAAMEDFRVDVVLGKGPGATAIPLDLAPFTLVGATTRSGLLTGPLRDRFGFTAHMDFYDAAELALVLTRSARLLGVQLTEGGAAEVAGRSRGTPRIANRLLRRVRDYAEVRADGVVSREVARAALRIYDVDALGLDRLDRAVLDALVRRFGGGPVGLSTLAVAVGEEADTVEDVSEPFLLRAGLLIRTARGRVATPAAFTHLGLEPQSDQLGRSQAPAALFGEDLPAS", "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA."}]}
+{"id": "function_test_1506", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTSQERGTRRGDTRGNVRDFPDSPADASGLTQRQKKVLEVIRSAVERRGYPPSVREIGEAVGLTSTSSVAHQLKVLQEKGFLRRDPNRPRAMEVLPIGGAKTGGRSRAGAAAAAGAPAETTALEAGTPTYVPLVGRIAAGGPILAEQAIEDVYPLPKEIVGEGTLFLLKVVGQSMINAAICDGDFVVVRQQPVADNGEIVAAMIDGEATVKRFRQRDGRVWLAPENPAFSDIPAEDATILGRIVAVMRRV", "output": "Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair."}]}
+{"id": "function_test_1507", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNFDTLKIADPEIYEVIQKETKRQRGNIELIASENFVTEAVMEAMGSQLTNKYAEGYPGKRYYGGCEEVDVAEDLARDRLKKLFNAEHANVQPHSGANANIGVYFAILKPGDTVLGMNLSHGGHLTHGSPVNISGTYYNFVDYGVDKETHLINYEEVRRIANEIKPKLIVAGASAFPRKIDFKKFREIADEVGAYLMVDMAHIAGLVAAGLHENPCDYADFVTTTTHKTLRGPRGGAILCKEKYAKMIDKAIFPGLQGGPLMHVIAAKAVSFKEALSPEFKAYQEQVIKNAAKLGEELKSRGFNLVSGGTDNHLLLLDLRNKNITGKDAEKLLDEVGVTVNKNTIPYDPESPFVTSGIRIGTPAVTTRGMKEDDMVTIAEIIGTIIDHPERIDEVSSMVKNLCEKFKLYE", "output": "Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism."}]}
+{"id": "function_test_1508", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MFKKLFTSESVTEGHPDKMCDQISDAILDAILEKDPAARVACETSVSTGLVLVAGEITTKCYVDIPKIVRKTIEEIGYTRAKYGFDSDTCAVLTAINEQSADIALGVDEALESKKGEHRDELEAIGAGDQGIMFGFACNETPELMPLPISLAHKLAKRLSDVRKDGTIGYLRPDGKTQVTVEYDGDKPVRVDTIVISTQHGPEVDAATIEKDMIEHVVQKIVPAELLDENTRYFINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDATKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGVSRPISILVETFGTGKIAEADIAELIGKHFDLRPAAIIRDLGLRNPGYRNVAAYGHFGRADLDLTWERTDKAELLRKEAGL", "output": "Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme."}]}
+{"id": "function_test_1509", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAASVRILGIDPGSRVTGFGVIDVRGRDHFYVASGCIKTPADAPLADRIAVIVRHIGEVVAVYKPQQAAVEQVFVNVNPASTLMLGQARGAALAALVSHKLPVSEYTALQVKQAVVGKGKAAKEQVQHMVVQMLGLSGTPQADAADGLAVALTHALRNHGLASRLNPSGMQVKRGRFQ", "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."}]}
+{"id": "function_test_1510", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MASSDIQVKELEKRASGQAFELILSPRSKESVPEFPLSPPKKKDLSLEEIQKKLEAAEERRKSHEAEVLKQLAEKREHEKEVLQKAIEENNNFSKMAEEKLTHKMEANKENREAQMAAKLERLREKDKHIEEVRKNKESKDPADETEAD", "output": "Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules (By similarity)."}]}
+{"id": "function_test_1511", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSGTNKQTNLHRQTETIRQLLGSKVVVLVGLMGAGKSTIGRKVANMLNLPFKDADTEIETVSRMTVAELFEAYGEVEFRDLERRVILRLLDDGPMVLATGGGAYMNAETRAAIAEAGISIWINADLDVLMERVSRRQNRPLLRNSDPRGVMQRLMDERYPVYALAELHLMTRDEKKEVIAAELIEVLAAHLEKEQAASAG", "output": "Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate."}]}
+{"id": "function_test_1512", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGNRKDHYYNKSKQEGYRSRAAYKLQQLDDRFDVLFGGASVVDLGAAPGGWLQVAAERAGARGKVVGVDFQSITQFETDAGLETVRGDMTEDETRQRVRDAANGSADVVVSDMAPDMTGEYDLDHARSVHLARQALETARELLDAGGHFVVKVFDGRDFQDLLADIEDEFAFVATHSPDASRDASSELYVVGKNHIVAPIAEGDEHTVEIVDTGDEGDGIARIEGYTLFVDDAAEGDTVDVTVTDLKPNYGFAERRDGA", "output": "Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit."}]}
+{"id": "function_test_1513", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTEGVGLPLWLLAELTYRCPLQCPYCSNPLDYAQHKNELTTQEWFDVFDQARQMGAVQLGFSGGEPLVRQDLEQLVAHAHQLGFYTNLITSGMGLTEQRISHLKQAGLDHIQISFQASDPVVNDALAGSKHAFEQKYEMCRLVKKYDYPMVLNFVIHRHNIDQIDKIIELCLELNADTVELAICQFYGWAFLNRQGLLPTQEQLIRAERITNEYREKLKAQNHPCKLIFVVPDYYEERPKACMNGWGKIFFTVAPDGMALPCHAARQLPISFPNVREQSLSRIWYESTGFNHFRGDAWMPEGCRSCPDKDRDFGGCRCQAYMLTGNASNADPVCGKSPYHQFIEQARAESEIDSSLEKLVFRNSRNSKQFTVQQNIPVQNIVDD", "output": "Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ)."}]}
+{"id": "function_test_1514", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLTKRIIPCLDVKEGRVVKGIQFVSIRDAGDPVELAKFYDEQGADELVFLDISASHEGRETMIEVVQQTAATLAIPFTVGGGIRTLDDMKRILRAGADKVSVNTSALERPSLIQEGSDFFGAQCIVVAIDARYSEEDGTWMVYTHGGRNKTTWSAIDWAKEAVRLGAGEILLTSMNQDGEKSGFDLGLTKAVREAVSVPVIASGGAGYAEHFYEVLAEEVDADAALAASIFHYKETSVAQVKEYLRAKGVAVR", "output": "IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit."}]}
+{"id": "function_test_1515", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSLLGSDAGELAGAGKTGVTVQSSLDAVKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIGTTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGTIGFATVRAGDIVGEHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSGKESGLFDMRDVLDLNNL", "output": "Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate."}]}
+{"id": "function_test_1516", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSKTHLTEQKFSDFALHPLVVEALENKGFQYCTPIQALALPLTLSGRDVAGQAQTGTGKTLAFLASTFHYLLSHPAEEGRQTNQPRALIMAPTRELAVQIHSDAESLSQVTGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNYINLGAIQVVVLDEADRMYDLGFIKDIRWLFRRMPSVDKRLNMLFSATLSYRVRELAFEQMNNAEYVEVEPLQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRCIIFANTKHRCEEIWGHLAADGHRVGLLTGDVAQKKRLRILEDFTKGDLDILVATDVAARGLHIPLVTHVFNYDLPDDCEDYVHRIGRTGRAGESGHSISLACEEYALNLPAIETYTGHSIPVSKYNSDALLTDLPAPKRLARTRTGNGPRRNSAPRRSGAPRNNRKRPG", "output": "DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA."}]}
+{"id": "function_test_1517", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGEALRGLKRTIMCGEPRENNIGQKVTVMGWVQRKRNLGGLIFVDLRDRTGIMQIVFGEEINKEAFEKSDNVKSEYCIAVTGEIVKRQSPNNDMETGAVELKGEDIKILSESETPPIYIKEGLDASENIRLKYRYLDLRRPDMQKIFMIRHKTCKVVRDFLDENGFLEMETPILTKSTPEGARDYLVPSRNYKGMFYALPQSPQIFKQLLMVSGYDKYFQITKCFRDEDLRANRQPEFTQIDMELSFIEEDDVIELNERLLAKVFKEVAGIDVKLPIERMPYKIAMEKYGSDKPDLRFGMEINDLTEAVKNSEFKVFKGAIEAGGSVRAIKAGNCATMGRKQIDKLQDFVKTYKAKGLAWIAYKEDEIKSPIAKFLTEEEMKAILEKMDAKVGDLILIVADKNNVVFESLGALRLHLAKELDIINKDEFRFVWITEFPLLSYNEEEGRYQAEHHPFTALMDEDVELLDTDPGKVRAKAYDIVLNGEELGGGSIRIHDSKLQEKMFNVLGFTKEKAWERFGFLLEAFKFGPPPHGGLAYGLDRMIMFLAGTENIKDVITFPKNQNAFCPLTEAPNVVDENQLEELGIKKIEKED", "output": "Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)."}]}
+{"id": "function_test_1518", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAVIYYDKDADLNLIKDKKIAIIGYGSQGHAHALNLKDSGLNVVVGLREGSKSWKKAEEQGLTVKTIEEAAKEADIIMILIPDEHQPEIYKKYIEKHLTEGKMLMFAHGFNIHYHQIIPPKNVDVTMIAPKSPGHIVRREYVEGRGVPALVAVYQDYTGKAKDIALAYAKGIGVTRAGVIETTFKEETETDLFGEQAVLCGGVTALIKAGFETLVDAGYQPEIAYFECLNELKLIVDLIYEGGLSFMRYSVSNTAEYGDYISQEKIVTKEVRENMKQMLKDIQTGKFAKDWILENQAGRPYFYTMRKKESEHLIEKVGKELRKMMPWLKERNVDEE", "output": "Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate."}]}
+{"id": "function_test_1519", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVNNMTDLTAQEPAWQTRDHLDDPVIGELRNRFGPDAFTVQATRTGVPVVWIKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHREGLPAADFSVFYHLISIDRNRDIMLKVALAENDLHVPTFTKLFPNANWYERETWDLFGITFDGHPNLRRIMMPQTWKGHPLRKDYPARATEFSPFELTKAKQDLEMEALTFKPEEWGMKRGTENEDFMFLNLGPNHPSAHGAFRIVLQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLDWMPKRLASYEKAALQNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKARPYSGYENFDFEIPVGGGVSDCYTRVMLKVEELRQSLRILEQCLNNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSYAHLQQIPAAIRGSLVSDLIVYLGSIDFVMSDVDR", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_1520", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "AAFALPAFASFEKDVITPAALEAVLNRKAPLYNIMMENDAILNVIANVKTVISNPVLEEALLKTNHGVNGIPCGESCVWIPCLTSAVGCSCKSKVCYRNSLDN", "output": "Probably participates in a plant defense mechanism."}]}
+{"id": "function_test_1521", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MENIMTLPKIKQVRAWFTGGATAEKGAGGGDYHDQGANHWIDDHIATPMSKYRDYEQSRQSFGINVLGTLVVEVEAENGQTGFAVSTAGEMGCFIVEKHLNRFIEGKCVSDIKLIHDQMLSATLYYSGSGGLVMNTISCVDLALWDLFGKVVGLPVYKLLGGAVRDEIQFYATGARPDLAKEMGFIGGKMPTHWGPHDGDAGIRKDAAMVADMREKCGEDFWLMLDCWMSQDVNYATKLAHACAPYNLKWIEECLPPQQYESYRELKRNAPVGMMVTSGEHHGTLQSFRTLSETGIDIMQPDVGWCGGLTTLVEIAAIAKSRGQLVVPHGSSVYSHHAVITFTNTPFSEFLMTSPDCSTMRPQFDPILLNEPVPVNGRIHKSVLDKPGFGVELNRDCNLKRPYSH", "output": "Catalyzes the dehydration of L-rhamnonate to 2-keto-3-deoxy-L-rhamnonate (KDR)."}]}
+{"id": "function_test_1522", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKYYKVDMKEAQKPDTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEEDKILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTITPPREGIIKRWTWPAGENDGSVALLKGQEMGRFKLGSTVINLFAPGKVNLVEQLESLSVTKIGQPLAVSTETFVTPDAEPAPLPAEEIEAEHDASPLVDDKKDQV", "output": "Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)."}]}
+{"id": "function_test_1523", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKLTEIQDPSFLKRMSVSELELFAGDIRRFLIEELATTGGHLAPNLGVVELTLALHREFDSPNDKFVWDVGHQAYVHKILTGRAGQFDTLRQHKGLCGFPKRNESVHDVWETGHSSTSLSAAMGIAVSNELKGNDDRAIAIIGDGALTGGMALEALNHIGAEQQNVIVILNDNEMSIAPNVGAMHQMLGRIRSSRKVRYAQDELETLIKKIPLIGGKLEKGGEKLKEAVKGALVPGMFFEELGFNYYGPVDGHDLTDLIEQLNYVKKEEGPVLLHVITKKGKGYRPAEYDGIGTWHGLGPYKIESGEVIKGKSKAPSYSFTVADTLTKMAREDDKLTLITPAMSVGSKLDCFEKEFPERMFDVGIAEQHAVTFAAGQATQGMKPVVSIYSTFFQRAYDQLVHDVARQNLDVTFTIDRSGLVGADGETHQGVFDIAFMRHVPNIRIVMAKDENELQHLLYSAVKYEGPIAVRFPRGEGIGVPMDETLHEISLDTWDVEREGTDVAIMAFGPQVQDALKIAELLEGDVSVRVINARTIKPLDEKMLNALYAEGIPLVTLEEAVLKGGFGSAVLEHANEQEAFPRVKRFGIPDWYIEHGGVNELLEEIGLLPGQIAEEVRSFVNQGKKQSV", "output": "Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)."}]}
+{"id": "function_test_1524", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNAQLSALQQQAQQLSASVTRPIPGSRKIHVPGSRPDLQVPMREIALTRTPTLFGGEENAPVTVYDTSGPYTDPEVRIDLSAGLPALRRGWVEERGDTEQLEGLSSSFGRDREHDPKLDAVRFPARSLPRRARAGANVTQMHYARRGIITPEMEFVAIRENQRLDAIRDAGLLQQHPGEAFGASIQKVITPEFVRDEIARGRAVLPNNINHPESEPMIIGRNFLTKINANIGNSAVSSGIAEEVEKLVWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVAIGTVPIYQALEKVDGRAEALTWEIFRDTLIEQAEQGVDYFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHKENFLYTHFEDICEIMKAYDVTFSLGDGLRPGCIADANDAAQFGELETLGELTKIAWKHDVQTMIEGPGHVPMQLIKENMDKQLRECGEAPFYTLGPLTTDIAPGYDHITSAIGAAMIGWFGTAMLCYVTPKEHLGLPNRQDVRDGIMAYRIAAHAADLAKGHPGAQVRDNALSKARFEFRWEDQFHLGLDPEKAKEFHDETLPKDAHKLAHFCSMCGPHFCSMKITQDVRDYAEAGMKEKSQEFRAGGAEVYRQG", "output": "Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction."}]}
+{"id": "function_test_1525", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIDPKLLRNNIEVVNAALAKRGVQLDVQEWASLETRRKDLQSKTEKLQAERNAGAKQVGQIKKSGGDASEIMARMQAIGDEIKAAEVALSELQNEIEQKALSIPNLPDESVPAGKDENDNVEISKWGTPRQFDFEIKDHTDLGEWMGGLEFETATKLTGSRFSVLKGPLARLQRALTQFMLDTHTLKNGYTEAYVPYLVNADSLRGTGQLPKFEEDLFKLQGEKEYYLIPTAEVPVTNFVRDEIIDADRLPLKYAAHTPCFRSEAGSYGRDTRGLIRQHQFDKVEMVQIVKPETSMQALEELTAHAEGILQALGLPYRKILLCGGDMGFGATKTYDLEVWVPSQNTYREISSCSNMGDFQARRMKARYRMDQKKTELVHTLNGSGLAVGRTLLAVMENYQRKDGSIEIPEVLRPYMGGATFID", "output": "Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)."}]}
+{"id": "function_test_1526", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTGIPPPSRFPEQPIPPWRRAVLKVGSSLLAADGGGLSPRFALDLAHFVSANITAGRQLVIVSSGAVAAGRALIPPLPESGGALAARQALAALGQAQLIALWQRFFDRPVAQVLLTHDDLRNRRRYLNARATLRELLHLGTLPVVNENDTVSVDELKLGDNDNLAAIVAALIDAQALFIATDIDGLYTTDPRHHSDAQPLHEVRTLTPENLAMAGDSSSTVGTGGMRTKLEAALKAGAAGIDTYLFNGRSSDVVRGLAQHRLRGTRIHPTCTPIAARKYWLRHAPVEPGAILIDAGAAAALAQQGASLLPGGVLSAEGDFRRGDMIQIATRSPDHPSHPLARGLVQYSAADVRRIAGCHSRDIQTLLGYTYGDTIVHRDDLVLL", "output": "Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate."}]}
+{"id": "function_test_1527", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDIALAIKALILGIVEGLTEFLPISSTGHLILAGQLLDFNDEKGKIFEIVIQFGAILAVCWEFRHKIIDVIKGLPNDPRQQRFAINVIVATIPAITLALIFGKAIKAHLFNPIVVASAFILGGFVILWAEWRERHRGETHDPRANALLEAAKAGAPRIETLDDLRISDAIKVGFAQCFALIPGTSRSGSTIIGGLLFGLSRKVATEFSFFLAIPVIFGATVYELYKSRALLSADDLSIFAVGFVAAFISAFFCVRWLLKFIATHDFRGFAWYRIIFGIIVLATAYTHLIAWQA", "output": "Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin."}]}
+{"id": "function_test_1528", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MANYFNTLNLRNQLAQLGKCRFMAREEFADEASYLKGKKVVIVGCGAQGLNQGLNMRDSGLDIAYALRAEAIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHTSVVQAVQPLMKDGAALGYSHGFNIVEVGEQVRKDVTVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVAEGTDAAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKVRAYALSEQLKTIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLGWREETGKTAFETAAQFEGKIGEQDYFDQGVVMIAMVKAGVELAFETMVAAGIVEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYAAVPLLQEFMTTLQAGDLGKQAQTSTSVDNAQLRDVNEAIRHHDIETVGRKLRGYMTDMKRIAVAG", "output": "Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate."}]}
+{"id": "function_test_1529", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRLAFWLYEGTALHGLSRVTNSMKNVHTVYHAPQGDDYITATYTMLERTPEFPALSISVVRGQDLARGVSRLPGTLQQVEEHYHPEVIVVAPSCSTALLQEDLSQLSMHSGVDTGKILVHDVNPFRVQEHESAEGLFTGLVKRYALEQSTTEKPSVNLLGFTSLGFHLRSDLISLRRILKTLGVEVNVVAPWGAGIEDLRNLPAGWVNVVPYHEMGPGAAHHLREKFGMPSLQGIPMGVNPTLDWIRDLLELLNVIAAEKGLPSIEMPPLTDFSLDGLSAPSGVPWFARTADMESFSGKRAFVFGDATHTVGMVKFLKDELGMQIIGAGTYLEQHADWIRDQLEGYLPVPLMVTDKFQEVAKKIEDEMPELVCGTQMERHSCRKLDVPCMVISTPTHIENHLIGYYPILGFDGADILADRVYTSCKLGLEKHLIDFFGDAGLEYEEEEPESISNGHAAAAGSEGGVPDSGEAGDAGDTDGMPWSPDAEKMLRKVPFFVRKKVRKNTENFARENGEATITAEVFKRAKEALGG", "output": "Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex."}]}
+{"id": "function_test_1530", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MMGFEWGFKPSSKITQSTVSSQGTGNVMIPTAGVKQKRRYANEEQEEEELPRNKNVMKYGGVSKRRPQPGSLIRGQPLPLQRGMELMNKNQLQQLLVDLMTKHPEIQQSVHTRVIGLDFSIQKCLDMLKQKSEAVYQSIPYNRSYESNKLDDYAFVRMKPQILEFLNCLVDFILDNIPPRLENLHASLKFLDICTELVIKLPRFELASNNYYYDKCIEQLSHVWCTLIEHVARDRIILLADNSSVWKSHMTRLQVYNEHSNGLLERPLQLFKSLDMGSPSAASSSTLSLQESIIYHHDTMTANENNNNSGSAATDSPFN", "output": "Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity)."}]}
+{"id": "function_test_1531", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRAVVQRSLEAKVTIEGNTVGTIDHGFVVLLGVGPTDTEAESDYLAEKISKLRVFSDPVGKMNLALADVGGQVLSISQFTLYADTHRGNRPSFTGAADPALGDRLYQAFNAKLKALGVPVATGEFGGDMQVSLTNDGPVTILFDTEAK", "output": "An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality."}]}
+{"id": "function_test_1532", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSRFFANGSESESESSEEEIQATNFNKASAFQFSDDEEEVKRVVRSTKEKRYENLTSIIKTIRNHKKIKDIPNTLSSFEDLTRAYQKALPVISKEENGITPRFYIRCLAELEDFINEVWEDREGRKNLSKNNSKSLGTLRQKVRKYIKDFEDDLSRFREAPDQESEAEDEVVALESDGGDAGDDSDAGVKPTEAAPKAVKSAPAKAAPADDDDSDDSIDWDSDSESETESSDDENQYQNMRERFLKRTTEKEEKDDDKRKDKRKEQKTKIRKRAEDDEDGEWETVVKGHVVEKPKMFEKDAEIDVPLVLAKLLEIMSARGKKRTDRRLQIDLLFELRDISDQHNLGTAVSVKIHFNIISAIYDYNQKISEPMKLEHWALLLEVMQSMMKLLLANADIIMSESVAEEHEEYATSPFYVRGCPLAAVERLDDEFVKLLKECDPHSNDYVSRLKDEVNVVKTIELVLQYFERSGTNNERCRIYLRKIEHLYYKFDPEVLKKKRGELPATTSTSVDVMDKLCKFIYAKDDTDRIRTRAILAHIYHHAMHDNWFQARDLVLMSHLQDNIDAADPATRILYNRMMANLGLCAFRQGNVKDAHHCLVDLMVTGKPKELLAQGLLPQRQHERSAEQEKIEKQRQMPFHMHINLELLECVYLVSAMLLEIPYIAAHEFDARRRMISKTFYQQLRSSERQSLVGPPESMREHVVAAAKAMRCGNWQACANFIVNKKMNTKVWDLFYESDRVREMLTKFIKEESLRTYLFTYSNVYTSISIPSLAQMYELPVPKVHSIISKMIINEELMASLDDPSETVGMHRSEPSRLQALAMQFVDKVTNLVDVNEKVFDMKQGNFFQRGNMGNRGDRGYNRNQNNQGGNWLGQRRDRNNRNRNQRGHHKNNQDRQQQQQQQVQTIDEE", "output": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation."}]}
+{"id": "function_test_1533", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPENIIAGIPVHFPFEPYDVQRAYMEKVIICLRDGTNGVLESPTGTGKTLSLLCSTLGWIRTRQSEVQLNMQKLQHDQQTQLTGAAGAGAAMGSEIAAVIGKSNNWGVPKVIYASRTHSQLTQAMRELKRTAYANMRAVVLGSRDQLCIHPDVMREQGNSNKVNMCKLKVHAKSCTFQLRVESKKDHPDFRGPSIMDIEDLVKVGQRLKMCPYFASKELVNSADITFMPYNYLLDPKARKANKIELSNAIVILDEGHNIEKICEESASVQIRSSDVAIAIEDVTHIMKIFTSSSDSQDTAGPDEPKDFTIDDLTLLKEMLLELEKAIDGVIVDNKADGATYPASYMYELLGKANFTHGNCATIVALLDKLVQYLMVASQHSMLRKGGSFMVLADLLNIVFANKGDIMSKVSCSFKVHAEIEESKQSQTNNKAQTGWLGKGNNNAASSASKTGRIINFWCFNPGFGMEQLLNTHVRSVILTSGTLAPLKPLIAELAIPVAQHLENPHIVNEAQVYVKIIGTGPDREQLISNYKNRDNPKYISSLGQTILNVSRIVPDGLLVFFPSYPMLNQCVDAWQASGLWADISSRKPIFLEPRGKDQFTSTMEEFYQAIRDSKGACFMAVCRGKVSEGLDFADRNGRAVIITGLPFPPLKDPKVILKRRYLETNRTRENQLLSGNEWYNLEATRAVNQAIGRVIRHRNDYGAILLCDARFQDASQVQQLSKWIRNHLGARPQSSPFGPIVRELRQFFKHAEQTIVQPVERAVEPVLHTICSKKEDQLTLAPITQIKREPGNTGTSKFQLASELAAKVEMANSIKTWTPADYANAAGRNAQSPKAPNPMDFMSRLNSNVTSIDFNADSGRDLVKIHKRERSSPTFHNESMGSKKRYRLINNIAQSELKEAPESRADFLREVRSVINSDQFRSFGKALLAYKTGGDDSFETLMLLLLDVMGAPKLRYLLHGMRRYLKNEHKSEFDVRLASLEAAQL", "output": "ATP-dependent DNA helicase implicated in DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates."}]}
+{"id": "function_test_1534", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTESVRLPAASLKPSTVALPGSKSISNRTLLLAALSDNVCEIHSLLKSDDTDRMLEALDKLGVQIEHLAEGRLKVHGTGGRFPNRSADLFLGNAGTAFRPLTAALAVLGGGYHLHGVPRMHERPIGDLVDALRIAGADVEYLGNEHYPPLHIGKRQDCGERVIPIKGNVSSQFLTALLMALPLTGQAFEIRMVGELISKPYIDITLKLMAQFGVQVANEGYRVFKIPADAHYHAPEHLHVEGDASGASYFLAAGLIAATPVRVTGIGANSIQGDVAFARELEKIGADVVWGENFVEVSRPKGRAVQAFDLDANHIPDAAMTLAIVALATRQTCTLRNIGSWRVKETDRIAAMANELRKLGAKVVEEAEAIHITPPETPTPDAVIDTYDDHRMAMCFSLISLLGVPVVINDPKCTHKTFPTYFEVFSSLTETAE", "output": "Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate."}]}
+{"id": "function_test_1535", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKYKDLRDFIRQLEAKGELVRISQPIDTDLEMTEIADRTLRAGGPALLFENPKNHDMPVLANLFGTPERVAMGMGQESVEALREVGKLLAYLKEPEPPKGLKDLWEKLPVFKQVLNMPAKVLKKAPCQEVVLTGDDVDLSKIPVQRCWPGDAAPLVTWGLSVTKGPHKKRQNLGIYRQQVIGKNKLIMRWLSHRGGALDFREWCQTHPGEPYPVSVALGADPATILGAVTPVPDTLSEYAFAGLLRGDKTEVVKSISNDLQVPASAEIVLEGYIAQDETAPEGPYGDHTGYYNEVDDFPVFTVTHITHRKDPIYHSTYTGRPPDEPAILGVALNEVFVPILQKQFPEIVDFYLPPEGCSYRMAVVTMKKQYPGHAKRVMMGVWSFLRQFMYTKFVIVCDDDVNARDWNDVIWAITTRMDPARDTVMIENTPIDYLDFASPVSGLGSKMGMDATNKMPGETDREWGVPIVMDEGVKKRVDDIWDSLGIM", "output": "Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis."}]}
+{"id": "function_test_1536", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVVGVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLSLAELKDKLDEMEGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALRENRLTLEAIRVTQSDRDLFKHLISEATDYVAADYMRHANERRVHLDQALAFRRELYTSRKQLAAEQYKHVDMARELGEHNGAEGSLEADYQAASDHLNLVQTALRQQEKIERYEADLEELQIRLEEQNEVVAEAAEMQDENEARAEAAELEVDELKSQLADYQQALDVQQTRAIQYNQAISALSRAKELCHLPDLTPESAAEWLDTFQAKEQEATEKLLSLEQKMSVAQTAHSQFEQAYQLVAAINGPLARSEAWDVARELLRDGVNQRHLAEQVQPLRMRLSELEQRLREQQEAERLLAEFCKRQGKNFDIDELEALHQELEARIASLSDSVSSASEQRMALRQEQEQLQSRIQHLMRRAPVWLAAQNSLNQLSEQCGEEFTSSQEVTEYLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGAEDQRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQIAEQLEGLTDCPEDLYLIEGDPQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPSLPIFGRAARENRIESLHAEREVLSERFATLSFDVQKTQRLHQAFSRFIGSHLSVAFEDDPEAEIRRLNGRRVELERALATHESDNQQQRLQFEQAKEGVSALNRLLPRLNLLADETLADRVDEIQERLDEAQEAARFVQQYGNQLAKLEPVVSVLQSDPEQFEQLKEDYAWSQQMQRDARQQAFALAEVVERRAHFSYSDSAEMLSGNSDLNEKLRQRLEQAEAERTRAREALRSHAAQLSQYSQVLASLKSSYDTKKELLNDLQRELQDIGVRADSGAEERARQRRDELHAQLSNNRSRRNQLEKALTFCEAEMENLTRKLRKLERDYHEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADELRSMSDKALGALRLAVADNEHLRDVLRLSEDPKRPERKIQFFVAVYQHLRERIRQDIIRTDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGLQSVSFGQVNSVRLNVNVRETHATLLDVLSEQQEQHQDLFNSNRLTFSEALAKLYQRLNPQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSILVMVVQSWEDEARRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPENISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGTQTEDTPSEAS", "output": "Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division."}]}
+{"id": "function_test_1537", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAKRDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDAQKRAAYDQYGHAAFEQGGMGGGFGGGFNGGADFSDIFGDVFGDIFGGGRGRQRAARGADLRYNMDLTLEEAVRGVTKEIRIPTLEECDVCHGSGAKAGTQPQTCPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCHKCHGHGRVEKSKTLSVKIPAGVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAALGGEIEVPTLDGRVMLKVPSETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLSEKQKQLLKDLQESFGGPTGEKNSPRSKSFFDGVKKFFDDLTR", "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins."}]}
+{"id": "function_test_1538", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MARKTLRARRFFSLIFPFFFITSVYAEQTPVSAKTVTVEAKNETFAPQHPDQYQSWKATSEQSAREDALAEDPRLVILWAGYPFSRDYNKPRGHAYAVTDVRETLRTGAPKTAEDGPLPMACWSCKSPDVARLIQQEGEDGYFHGKWARGGPEIVNDLGCADCHNTASDDFAQGKPALTLSRPYAERAMEAIGKPFDKAGRFDQQSMVCGQCHVEYYFDGKNKAVKFPWDEGMKVENMEQYYDAIAFSDWTNSLSKTPMLKAQHPEYETWSAGIHGKNNVTCIDCHMPKVQNAEGKLYTDHKIGNPFDNFAQTCANCHTQDKASLQKVVAERKQAIHDLKIKVEDQLVHAHFEAKAAWDAGATDAEMKPILNDIRHAQWRWDLAIASHGIHMHAPEEGLRMLGSAMDKAADARTKLARLLATKGITHEIPLPDISTKEKAQKAIGLNMQQINAEKQDFLKTVVPQWEDQARKNGLLSQ", "output": "Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process."}]}
+{"id": "function_test_1539", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVNNMTDLTAQDAAWSTRDHLDDPVIGELRNRFGPDAFTVQATRTGIPVVWVKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHRDGLPAADFSVFYHLISIERNRDIMLKVALSENDLRVPTFTKLFPNANWYERETWEMFGIDIEGHPHLTRIMMPQTWEGHPLRKDYPARATEFDPFELTKAKQDLEMEALTFKPEDWGMKRGTDNEDFMFLNLGPNHPSAHGAFRIILQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMTPVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLEWMPKRLDSYEKAALRNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKWRPYSGYENFDFEVPVGGGVSDCYTRVMLKVEELRQSLRILQQCLDNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPAQESFQMVEATKGINSYYLTSDGSTMSYRTRVRTPSFAHLQQIPSAIRGSLVSDLIVYLGSIDFVMSDVDR", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_1540", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLDNTRLRIAIQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFGGCRLSLATPVDEAWDGPAALDGKRIATSYPHLLKRYLDQKGVSFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMAQSKQQLIDKLLTRIQGVIQARESKYIMMHAPSERLEEVIALLPGAERPTILPLAGEQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME", "output": "Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity."}]}
+{"id": "function_test_1541", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMSARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKETGEKDALVVMKGTLHGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLVCFSASGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNIAEPKALIGFAGPRVIEQTVREKLPPGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAKLMNLPAPNPDAPREGVVVPPAPDQESEA", "output": "Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA."}]}
+{"id": "function_test_1542", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKTDTSTFLAQQIVRLRRRDQIRRLMQRDKTPLAILFMAAVVGTLTGLVGVAFEKAVSWVQNMRIGALVQVADHAFLLWPLAFILSALLAMVGYFLVRKFAPEAGGSGIPEIEGALEELRPVRWWRVLPVKFIGGMGTLGAGMVLGREGPTVQIGGNLGRMVLDVFRMRSAEARHTLLATGAAAGLSAAFNAPLAGILFIIEEMRPQFRYNLISIKAVFTGVIMSSIVFRIFNGEAPIIEVGKLSDAPVNTLWLYLILGIIFGCVGPVFNSLVLRTQDMFQRFHGGEIKKWVLMGGAIGGLCGILGLIEPEAAGGGFNLIPIAAAGNFSVGLLLFIFIARVVTTLLCFSSGAPGGIFAPMLALGTLLGTAFGMAAAVLFPQYHLEAGTFAIAGMGALMAASVRAPLTGIVLVLEMTDNYQLILPMIITCLGATLLAQFLGGKPLYSTILARTLAKQDAEQAAKSQNAPAGENT", "output": "Proton-coupled chloride transporter. Functions as antiport system and exchanges two chloride ions for 1 proton. Probably acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response."}]}
+{"id": "function_test_1543", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKQLFLIIGAPGSGKTTDAELIAKNNSETIAHFSTGDLLRAESAKKTERGLLIEKFTSQGELVPLEIVVETILSAIKSSSKGIILIDGYPRSVEQMQALDKELNAQNEVVLKSVIEVKVSENTAKERVLGRSRGADDNERVFHNRMRVFLDPLAEIQNFYKNKNVYKAINGERSIEEIVNEMQKYILSFAN", "output": "Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism."}]}
+{"id": "function_test_1544", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKYYKVDMKEAQKPDTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEEDKILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYVPGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTITPPREGIIKRWTWPAGENDGSVALLKGQEMGRFKLGSTVINLFAPGKVNLVEQLESLSVTKIGQPLAVSTETFVTPDAEPAPLPAEEIEAEHDASPLVDDKKDQV", "output": "Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)."}]}
+{"id": "function_test_1545", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAWNVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPGGPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRDNGTDDQTRADIARAFEDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLRAKLAEMMKKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGATADLGVSVRPRWPLAELPAA", "output": "Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction."}]}
+{"id": "function_test_1546", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTAPRTLYDKIWDDHVVDVEPDGSALLYIDRHLVHEVTSPQAFEGLRVAGRTVRAPHKTLAVVDHNVQTSDRSKGIEDPESRTQLEALAENVRDFGIEFYDALDQRQGIVHIIGPEQGFTLPGQTIVCGDSHTSTHGAFGALAHGIGTSEVEHVLATQTLIQRKAKNMRVTVDGTLPRGVSAKDIVLAIIGEIGTAGGTGHVIEYAGEAIRALSMEGRMTICNMSIEGGARAGMVAPDETTYAYVNGRPKAPKGAAFDAARRYWESLATDEGAHFDREIRLDAANLPPLVSWGTSPEDIVSILGTVPDPAQIADENKRQSKEKALAYMGLTPGTRMTDVTLDRVFIGSCTNGRIEDLRIVAKMVEGRKVHDSVSAMVVPGSGLVKAQAEAEGIDRILKDAGFDWREPGCSMCLGMNPDKLRPGERCASTSNRNFEGRQGPRGRTHLVSPAMAAAAAVAGRFVDIREWRG", "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."}]}
+{"id": "function_test_1547", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKKNQFLKESDVTAESVFFMTRRQVLKALGISAAALSLPHAAHADLLSWFKGNDRPPAPAGKPLEFSKPAAWQNDLPLTPADKVSGYNNFYEFGLDKADPAANAGSLKTDPWTLKISGEVAKPLTLDHDDLTRRFPLEERIYRMRCVEAWSMVVPWIGFPLHKLLALAEPTSNAKYVAFETIYAPEQMPGQQDRFIGGGLKYPYVEGLRLDEAMHPLTLMTVGVYGKALPPQNGAPVRLIVPWKYGFKGIKSIVSIKLTRERPPTTWNLAAPDEYGFYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYAEQVASLYRGLDLRENF", "output": "Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide."}]}
+{"id": "function_test_1548", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEASNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFVTVASTESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDMFGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE", "output": "Catalyzes the synthesis of GMP from XMP."}]}
+{"id": "function_test_1549", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAAFLLRVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDLPLRLRWQNKSRDIHYIVRHLTETLGTDNLAESHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRVFKVIKDRFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPLPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRRQRFSVRFV", "output": "Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation."}]}
+{"id": "function_test_1550", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSLKQAVLDICQGQQLTLSQFGQLDTQLGRLFADAVNALLKEQNLQARDIVAIGCHGQTVWHEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHPTERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGKVILPLLQNMLCDPYFSQPAPKSTGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAVTISEQVLLSGGCERLMVCGGGSRNPLLMARLAALLPGTEVTTTDAVGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGASQETVLGAIFPANP", "output": "Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling."}]}
+{"id": "function_test_1551", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYGKTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIAAVQQATNGHCAICDTMAQKRQYASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSRNLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGWATALQLIALSARQNTHSAHKSARRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAILRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCYHPLFGNFLRQRCQWELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSLLEESLKALPWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREGTMHAEFNALRAQVAINDGSPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSLALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGDLDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTSDKAAAANWLRHTAKPEFANNHFLQGQWRNIARAQILLGEFESAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQAGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRILREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGVAHRQAAVQHAQKLLKMMGYGV", "output": "Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box."}]}
+{"id": "function_test_1552", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGICYGMQTMAMQLGGHVEASNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFVTVASTESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDMFGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE", "output": "Catalyzes the synthesis of GMP from XMP."}]}
+{"id": "function_test_1553", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLNDSKKLSEKRRLALCEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAPEYVLIDGNRCPKLPMPSMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFAQHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS", "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."}]}
+{"id": "function_test_1554", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFCRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYMRPAAAV", "output": "Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis."}]}
+{"id": "function_test_1555", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLKKSDNKMTDQAYWCVVSGSDIWVNDDQFPFGSAEELGLSVEHAICIGQHQGRKVYWLNDCDVEIELSMVSLRDLLHWPESSFLIASKAIQYGHMTQSMRFCPQCGGRNHLNHNQVAMQCGDCRTLHYPRIFPCIIVAVRNDNKILLAQHPRHKTGMYTVIAGFLEVGETLEQCVAREVKEETGIDVSNIRYFGSQPWAFPSSMMMAFLADYAGGTLKPDYSELSDAQWFDVTSLPDVAPVGTIARQLIENTVDDIRKASVAEQELEH", "output": "mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates."}]}
+{"id": "function_test_1556", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSATFNFCAGPAMLPKPVMDKAQSELLDWNSMGTSVMEISHRSKEFIALTNQAEADLRQLMDIPANYHVLFMHGGGRGQFSAIANNFLGDKGRALYLVDGSWSSAAVEEAKKLVGEENIDTINIVENNNGINSVVLPSLSNIDKDYRYLHYCPNETVDGIEIFDTINSPWPVIADMSSNILSRKIDVNQFALIYAGAQKNIGPSGLSIVIVRNDMLSLPSLPQSSIMDYKLAVKHGSMYNTPPTFAWYLAAEVFAWLKVSGGVDSVELINIEKAMRLYQCIDELDFYKSGVAVENRSRMNVTFQLVNAELDNQFLEEAKQAGLVALKGHRSVGGMRASIYNAMPIEGVIELVKFMQTFAKKHS", "output": "Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine."}]}
+{"id": "function_test_1557", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTKDIMDAVFIKEMAKTTSNLYRLGWDERNGGNITYLLDEKEVVEYLDVKQIIRTIPMDFDGEKLAGKYFLVTGSGKYFKNVEEAPAVNLGVIQVSEDGKAVHLLWGYTDGGLPTSELPAHFMSHIARLSVDPENRVVMHCHATHLLAMTFTHELTEREFTRTLWQMCTECLVVFPEGVGIIPWLVPGTNEIGEATSEKMKENRLIVWPHHGIYGAGKSMDETFGLIETAEKAAEVYTIVMSQGGIKQAITDEQLKALGERFSVEAKAGYLNN", "output": "Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde."}]}
+{"id": "function_test_1558", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSLILAIYGKGGIGKSTTSANLSAAMALKGAKVLQIGCDPKHDSTFPLTGHLQPTVIDVLDSVNFHLEDVSKEDVIRTGFAGVDTLESGGPPAGSGCGGYVVGETVKLLKEFGLYDKYDVIVFDVLGDVVCGGFSAPLNYADYGLIIACNDFDSIFAANRLCLAIAQKSQRHKVKLAGIIANRVDYEYGGGTSLLDQFAEKVGTKVIGRVPYHDLIRRSRLAGKTLFEMEGPGKEECTRPFEEMAEYLLAQPQATIPNPYHDRAIFEAIGGWR", "output": "Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP."}]}
+{"id": "function_test_1559", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAKRDYYEVLGVSKDASKDEIKKAYRKLSKKYHPDINQEEGAEEKFKEISEAYEVLSDENKRANYDQFGHDGPQGGFGGQGFGGGQDFGGFGGGFEDIFSSFFGGGAQRDPNVPRKGDDLQYTMTVTFEEAAFGTEKEISIRKQVKCETCDGSGAKPGSKKKTCHYCNGSGHVSVEQNTILGRVRTEKVCPVCNGTGEEIEEPCPTCHGKGTETKNVKIKVKVPEGVDNDQQIRLAGEGAPGHNGGPQGDLYVVFRVEPSDTFEREGDDIFYNLNVSFPQAALGDEIKVPTLKGHVMLSVPEGTQNGKQFRMKEKGIKNVHGYGYGDLFININVVTPTKLNDKQKSIMREFAEVSGEEITEQPTNFKERARRFFKGE", "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins."}]}
+{"id": "function_test_1560", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKKLFLIGKSLKHSISPFIHNRILSEFDIDAIYSNLELLDTEMLKEFVEMVRKDEDVVGFNITIPYKEDILEFCDEVSEDVRIIKAANTVKKEDGKLLAYNTDWIGFKRSLEDRGVDVKDKKILVLGSGGAAKACIYGLYRMGAKEVFVANRTYEKAEKLKEVFQDILKILPVEWLRRYEFKYDIIINTTSVGMFPNIESSPFDFENYVAGVPVFVYDMIYNPLKTAFLKEAEKKGIKIENGLKMLVYQAIEAEMIWFDIVNLSPNFLLEILNDTEKNFGLGIYKVIG", "output": "Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)."}]}
+{"id": "function_test_1561", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "GLWSKIKETGKEAAKAAGKAALDKIAEAV", "output": "Has antimicrobial activity."}]}
+{"id": "function_test_1562", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MFDAAPIKKVSVVIPVYNEQESLPELIRRTTTACESLGKAWEILLIDDGSSDSSAELMVKASQEADSHIISILLNRNYGQHAAIMAGFSHVSGDLIITLDADLQNPPEEIPRLVAKADEGFDVVGTVRQNRQDSLFRKSASKIINLLIQRTTGKAMGDYGCMLRAYRRPIIDTMLRCHERSTFIPILANIFARRATEIPVHHAEREFGDSKYSFMRLINLMYDLVTCLTTTPLRLLSLLGSVIAISGFSLSVLLIVLRLALGPQWAAEGVFMLFAVLFTFIGAQFIGMGLLGEYIGRIYNDVRARPRYFVQQVIYPESTPFTEESHQ", "output": "Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides."}]}
+{"id": "function_test_1563", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MREHRPVIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAGPEIVSYLKALGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNIHAAGGVEMMKAAREGLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEVQVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPVAAYHAIKDEWTQDWN", "output": "Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP)."}]}
+{"id": "function_test_1564", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNEAFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGVFKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYIGLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKAGELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSFVRLFV", "output": "Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin."}]}
+{"id": "function_test_1565", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSEATTTLDGWYCLHDLRSIDWAAWKTLSSDERGQAVSEFLNVVEKWNDVAAAKKGSHAMYTVVGQKADIMLMILRPTMEELNEIETELNKTTLAEYMVPAYSYVSVVELSNYLPADEDPYQNPQILARLYPELPKANHICFYPMDKRRQGDDNWYMLPMEERKKMMYSHSKIGRQYAGKVRQVISGSVGFDDFEWGVTLFADDVLQFKKLIYEMRFDEVSARYGEFGTFFVGNILPDEKVEKFLHI", "output": "Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway. The reaction occurs in a stepwise manner with a three-propionate intermediate."}]}
+{"id": "function_test_1566", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKYDIKLRFEVEGIVEKTDVIGAIFGQTENLFGDEFDLRELQDKGRLGRIIVEIRTKGGKSEGEIIIPSNLDRIETALIAAMVESVDKVGPYNSKFELIEIEDIRAEKLKKIIERAKGILSSWSKEKSLDIKEVINEISSAVKVGEITEYGPERLPAGPDVDKDPNLIIVEGRADVINLLRYGYKNVIAVEGATSRIPETVVSLSKMKKTVIAFLDGDHGGDLILKELLSNNVKIDFVARAPVGREVEELTGKEIAKALSNMMPLTQYLKKIQEAEQAIAKNVIAKEEKPIQLEATQQLVQITLPQNVLEEIKKLPGTLEGVLYDNNWNLIEKVQVRDIIPKLEAYEDNKVAYIVFDGVITQRLLDLASQKNIKMIIGARIGGINKRPQNVDILTFTDIISS", "output": "RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteromeric, adenine-rich transcripts and the exosome."}]}
+{"id": "function_test_1567", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLLTTEPTATQIRDERIYATMGLSDDEYALVVSLLGREPNYTEIGLFSVMWSEHCSYKNSKPVLRKFPTTGKHVLQGPGEGAGIVDIGDGQAVAFKIESHNHPSAIEPYQGAATGVGGIIRDIFSMGARPIALLNSLRFGDLNESRVKHLFGHVVSGIAGYGNCVGIPTVGGEVAFDPAYSGNPLVNAMCVGFIRHEDIQKGIAEGVGNSVMYVGATTGRDGIHGATFASEELGEDADEKRPAVQVGDPFMEKLLIEACLEVIKHPALVGIQDMGAAGLTSSSAEMASKAGMGIEMNLDLVPQRETGMTPYEMMLSESQERMLLVVKAGHEDEIEAIVTKWGLHAIKVGEVIEEKVLRLVHQGEVAAEVPVDALAEDAPVYHKPSKVPAYYEAFQAMEPVTPIVEDMMATWKDVLAMPSIASKRWVYEQYDHMVQTSTVVAPGSDAAVIRIRETEKSLAMTTDCNAKYVYLDPRVGGAIAVAEAARNIVASGAEPLALTDCLNFGSPDKPEGFWQLDQAVEGMAEACRTLDTPVIGGNVSLYNESNGQAIYPTPVVGMVGLIEKPEHITTSFAKQAGDVVFLLGETKAEFGGSALQMLQDGKVSGHAPTLDLENERQTQKVLLHAIREGLVTAAHDVSEGGLAAALPELVFGTGFGVDVTIDTDLVTALFSESQSRFLVTVDKAHAEAFARMTNGTAIGTVTEASTLVVRASDRLIEMDVQELERVWEGAIPCYMTSEA", "output": "Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL."}]}
+{"id": "function_test_1568", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MHWPPEFGKVFMILEDGFSRRFHYLRLSVTEACNFRCTYCLPDGYRPDGRKSFLTVDEIRRVVYGFAELGVKKIRLTGGEPSMRRDLPAIIETVANTAGIEKVAMTTNGYRLKDRAQQWFDAGLRSLNVSIDSLDPRQFQLITGENKLVEILEGLEAAQKAGFRKIKVNTVLLKNLNDHELSQFLFWLKKQPIQLRLIELMQTGEMDARFQKHHQSGLPVKTRLLREGWTQQNRNLTDGPAEVFSHPDYQGQIGLIMPYSKDFCTNCNRLRVSSVGKLHLCLFGEEGVPLRDLLQADEQNSELQSRILEGLTHKRETHFLHDGDSGVTPHLASIGG", "output": "Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate."}]}
+{"id": "function_test_1569", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSLEEQQSDDPAELESGVSRGDELAELLGDLVVGREEHLNAPGLVIRPDEVQDALFKLRDEAGFDHLSCVTAQEYEDRYESIYHLTKFDDRTDEVSVVVPTSKDNPVSQSAEPVFRTADWHEREAYDLVGIQYEDHPDLRRILLPETWQGHPLGLDYDQDRPQIATLREHANPLEEDHRAGDSNTMYINIGPHHPATHGVLHVETVVDGEQVVDLESDIGYLHRCEEQMCQQGTYRHQIMPYPDRWDYISSGLLNEWAYARAAEDLADIEVPEYAQIIRTMGAELCRIASHMIALGTFALDVYGDFTAIFMYAMRDREIVQNILEDLTGQRMMFNYFRLGGVVWDLPEPREEFFEKIRDFMDGLPQALEEYHDMITSNEILQARTVGTGVLSPEVAKSYGATGPVARGSGIDYDLRRDDSYGYYDELEWDVVVEDGCDNFSRLLVRMREVEESAKIIQQCVDLLEDWPEDERNIQANVPRTLKPDEDTEIYRAVEGAKGELGIYIRADGTDKPARFKIRSPCFSNLQTLPEMSEGEYIPDMIASLGSLDIVLGEVDR", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)."}]}
+{"id": "function_test_1570", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDNTIGPRVDPSIRAFDFTALFEECFLDILPWSLFLLMLLVRLKFLLNRPKIIRVDRLCLIKEALWTLYAVVKLAQLILWASIAAFTTAGTVPAAALAFVGCMGGSVLSYFEHCRSRRPSSLLGILTLLILLCDVTRVRTMWLMDQPRAISILTTAALPINILLLVFESLTKTAVANEKEASRSKEEIVGILNRSVFWWLNSLFILGRKHVLHMGNLPRVDSKVLTSYAAPKVYERWESKPQSLMLQSLQAYPMTLLRGGLCRLFTALFVTSQPLLLKRTIRWFSEPSTPVSDAEGYGLIGAYLVVYGGRAVFTALAQHQNYRLITMIRASLVSLIYDRTLTLDLVEAKESAALTLMSTDVERIGQGLQFVHEIWATPAEFGVAIFLLQREVALGSLAPVIIIIVAIVGTVLLSMKIDPHQKEWIGAIERRIGSTTDMLRNMRGVKMSGFEDALTSILQAMRVEEVNISRATKLLFIGCQVFSTATATISPVLGFTIYVLMQRAQGKPGLASSSAFTSLSLFSILSSSVYIFLTSVPAIFSGISCFARVENYLVSENITGPTDAEGQDSEASSISAEKISIIAPKIAPSDYLLVIRDGSVRWKGQEKAVLSQINLCIEQGSFCVISGSVGSGKSSLLYAILGEASLKADTFHISTTSIAYCQQSPWLPDISVKECVLNGRDWDEDLYKRVIHACALSEDLAQLSAGDHTKVGYEGGTLSGGQRQRVALARALYSRRRLLLLDDTFSALDPKTEKSVSGNLFSSSGLLRELGTTVICTTGKPGNSNKYADYTLDLNKEGEAQLRNTQKDMQDDEIEASTYSREQNGPKKQEEDANHESNQSPETSQEHELAQESVPTFSSMIFYLRSTGMGFFALSFSLSLVYSFWQNFPTIWVNLWTQHDAKHPYGDLAKYIGVYILCAVLALVTHTVVTWFVNMACNGIDGAAVRAGPTRDTPENSGTASITGRGYVVFTNKHRAPMSYFESVDIGTITNHFSQDMEKVDLEIPLTGVQALFAFTSALVQLVMLSIGTKWMAITFPFIIAILAIIQRQYLKTSRQLRLLDLEAKSPLYSHFTETLSGLATIRAFGTHKQCQSINTERLDCSQGPFYLLYCAQRWLTLVLNLVIGAMAILMMGVTIKLRGSTGAGYIGLAFVNLTTFSQSIQSLLTWWTMMEASIGAVHRVQQFEKETPQEDVLGQVTSPPHSWPKAGLIELKELSASYLSSVSPVLRNVTFTVQPGQKVGICGRTGSGKTSLILCLQRMIKINSGSILIDGLNTSHVPAKTLRERLICIPQDALIFNGTVRLNLDPQSSFTDKQLQDNLRRVELWDLISSKGGLDATMQDGLLSHGQLQLFCLSRVLQKKSPIVILDEVSSSADEESQRLISKIIREDFKDRTVISIAHRLQQIADFDIILVFSQGQLVEQGSPEDLLGRDVSLFQDLFSQQDK", "output": "ABC-type transporter; part of the gene cluster that mediates the biosynthesis of gramillins A and B, bicyclic lipopeptides that induce cell death in maize leaves but not in wheat leaves . May be involved in the secretion of gramillins (Probable)."}]}
+{"id": "function_test_1571", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAVISLLQGLSVGQQIGTAAAISVFVLTSIVVYGCYLHPLSHVPGPFLAKFSPIWGMRALYRMKFNSELQALHEKYGPVVRVAPNEVSFATLEAETAIYANQEDGRFSKAGTFLTLFSDLVLNAPTLITIPDPALHKRLHKVIQQAFTPQALASQEPIQKLHIEKAIPDFDETADKGYHIDLADKLETMFWEIIGDLAFGEPLMAGKRPTYEKLKQLGKGSMPMVEALSFMLVMPGVAPTLEMARSFLSAMPMSSQLSKLVPSTKLRDCVERKDGREDFLSAIMGSEKQGLTLDADAFFSNAMGLTLAGYQTTATTLASTFYHVLRYTDAYKTLCTEIRSAFNDEAEITGERLARLPFLNACIRETLRLLPPANGKTAQRTAPSCTIADTYIPAGTIVSADLYTIQRSPKYFVDPARFHPERWLEDAEKNGFNGDNRSASRPFLIGSRACIGRHMAQQSIRLIMATLLWRYDFELLDPDGFIWERDAGSSLIYTDYKLPVHVKRFQ", "output": "Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of terpestacin . The bifunctional terpene synthase tpcA converts isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) into the sesterterpene preterpestacin I . The C-terminal prenyltransferase (PT) domain of tpcA catalyzes formation of GFPP, whereas the N-terminal terpene cyclase (TC) domain catalyzes the cyclization of GFPP into preterpestacin I . The cytochrome P450 monooxygenase tpcB then hydroxylates preterpestacin I to yield 24-hydroxypreterpstacin I (renamed as preterpestacin II) whereas the cytochrome P450 monooxygenase tpcC further hydroxylates preterpestacin II to yield 16,17-dihydroxypreterpestacin II (renamed as preterpestacin III) . Finally, the FAD-dependent monooxygenase tpcD converts preterpestacin III into terpestacin ."}]}
+{"id": "function_test_1572", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDDKIALTSNDGERPRMKKDWRFWTIFAALMLIAFLAALDMTMISTALPAIVAALPPSSIAANWITSAFLLPMVASQPIFGGLSCSLGRKNSVISALVIFLVGSIVCATAKSVLVLVVGRGVQGLGGGGIHALSEIIMSDLTTLRERGVYFGLIALVFAVAGFIAPVLGGVFSHSSWPWIFWINLPIGAVALVLLVLFLNIRVPLLTGRQKWEKLDLVGNAILFGSVTAVLIAVTEGGIKYRWSDARVWVPLVVGLIGLVAFLMVEWIPGPLCRQPVFPRDLFANRTAAVAYLQTFLHGVIFYGIIYMVPIYFQAIKDRTPLQSAIWSFPLTAPSTPLALIAGLLISISGRYKKLIFIGWALMAGGVGWLTHWSVGTSKAEWAISQIIAGAGIGIMFPITLPPIQASLPVERLEAATAAYAFSRTFGAVWGITGATTIFATQAAKKLRPDYGQLEPLGLNDFTVIAFAESLRYLPEQLQVLVKKVYADAISDSFWLFVPLAIIGFASTFLLKDLPLPDFIKSQAVLEEKGASENASPPESLA", "output": "Glycosyltransferase; part of the gene cluster that mediates the biosynthesis of mannosylerythritol lipids (MELs), surface-active substances that enhance the availability of water-insoluble substrates (Probable) . MMF1 is directly involved in the secretiopn of MALs (Probable)."}]}
+{"id": "function_test_1573", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "PIAGSMVLAAILLKLGGYGIIRMMQILPTTKTDLFLPFIVLALWGAILANLTCLQQTDLKSLIAYSSISHMGLVVAAIIIQSPWGLSGAMALMIAHGFTSSALFCLANTTYERTHTRILILTRGFHNILPMATTWWLLANLMNIATPPTLNFTSELLIMSTLFNWCPTTIILLGLSMLITASYSLHMFLSSQMGPTPLNNQTEPTHSREHLLMTLHLAPLMMISMKPELII", "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)."}]}
+{"id": "function_test_1574", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIDVAPESKKAKDLKGDFWDAKNIQISIGEIITEEKPPEEEVKGPKPRPHVTDLRSWDMKLLERYEPFYAPFCDMCCLCTYGKCELLGKKGACGIDAATQQARTVLLACLIGTAAHAGHARHLVDHLIERLGEDYKIDLGSNVDIEAPITRTVMGKRPATLGDLREVMDYAEEQMSHLLSACHTGQEGDSKDFESKAFHAGLMDDLTREVADLAQIVALDLPKGDEDAPLVELGFGTIDTEKPVVLCIGHNVLPGADIVDYLDENEMEDQVEVCGICCAAIDVTRYNEAAKVVGPLSKQLRFIRSGVADVIVVDEQCVRTDVLEEALKNRSAVIATTDKMCLGLPDMTDEDPDKIVNDLINGNIEGALILDPEKVGEVAVKTAMKLAPIRKSLKKLPDIDEIIELASECTDCGWCQRVCPNSLPVMDAVKKAADGDLSKLEEMAIEELCYTCGRCEQECERNIPIVSMVTKAGERRVKDEKYRIRAGRGPAQDVEIRRVGAPIVLGDIPGVVAFVGCSNYPEGGKDVALMAKEFLERNYIVVTTGCGAMSIGEYRDEDGQTLYEKYGGQFDAKGLVNMGSCVSNAHVSGAAIKIANIFAQKPLEGNFEEIADYILNRVGACGVAWGAYSQKAAAIATGVNRWGIPVVLGPHGSKYRRLFLGRADDEEKWKLKDLRTGEVIDGEPAPEHLLYAAENREEATVMIAKLCIRPTDTPKGRQMKLSNYIDLHRKYLGTIPDDIDRFIRTEKDIPIVYKRDVMKILEEKNWKPRELPKEPSLLER", "output": "Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase."}]}
+{"id": "function_test_1575", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRFLDGHQPRFDLTYKDVFIVPHRSDVASRFDVDLSTYDGSGTTIPVVVANMTTVAGQRMAETVARRGGLVILPQDLPIATVQQAVEFVKSRDLVIDTPVLLTPNDSVSDATTLIHKRAHGVAVVAFEGRPIGLVRESSCLGVDRFTRVRDVATTDFVTAPVGTDPRKIFDLLEHAPIDVAVLTNADGTLAGVLTRTGAIRAGIYTPATDARGRLRIGAAVGINGDVAGKAQSLAEAGVDVLVVDTAHGYQVKTLEAIKCVASLNLGVPLVAGNVVSAEGTRELLNAGATIVKVGVGPGAMCTTRMMTGVGRPQFSAVLECASAARKLNRHVWADGGVRHPRDVALALAAGASNVMIGSWFAGTYESPGDLMRDRHDQPYKESYGMASKRAVVARTVADSSFDRARKALFDEGISTSRMGLDPDHGGVEDLIDHITSGVRSTCTYVGASTLAELHEKAVVGVQSAAGFAEGHPLPSGW", "output": "Involved in the purine-salvage pathway. Catalyzes the NADPH-dependent conversion of GMP to IMP."}]}
+{"id": "function_test_1576", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEGSMALSKWHAYSRLMRIDRPIGSLLLLWPTYWALWIAAQSIPSLHILIVFTAGVFLMRAAGCVINDFADRHFDGHVERTKHRPLPSGDVTEKEAKILFASLVGLSFLLVLTLNSMTIWLSVAGLALAWIYPFVKRVSHLLQVVLGAAFGWSIPMGFSAVSESLPLVCWVLFLVNILWSVIYDTQYAMVDRNDDLKIGVKSTAILFGQYDKLIIGILQIVMIVLLVLVGSLADLGAVYYIALSLSALLFIYQQKLMVDRERAPCFKAFLNNNYVGLILFIGIFLSYL", "output": "Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate."}]}
+{"id": "function_test_1577", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTEVESSTENNVIVNKNKRYRRDKPWDTDDIDHWKIEPFTKDDSKESFLEESSFATLFPKYREKYLREVWPHVTRALDKFGITCVLDLVEGSMTVKTTRKTFDPYSILDARDLIKLLARSVPFPQAVKIMQDGVACDIIKIGNILRNKERFVKRRQRLIGTNGQTLKALELLTQCYILVQGTTVAVMGGYKGLKEVRRIVEDCMHNIHPIYHIKELMIKRELAKDPTLANESWDRFLPQFKKRNVARRKPAKIRETKEYTPFPPAQPPSKLDLEIESGEYFLKKEEKERKKRAEKKEQQKEKKKEKEKERMKAFIPPEESSKKRKRD", "output": "Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly."}]}
+{"id": "function_test_1578", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIMSFFDQFLSPSFLGIPLIALAISIPWLMFPTPTNRWLNNRLLTLQAWFINRFIYQLMQPMNLGGHKWAILFTALMLFLITINLLGLLPYTFTPTTQLSLNMAFALPLWLTTVLIGMFNQPTIALGHLLPEGTPTPLVPVLIIIETISLFIRPLALGVRLTANLTAGHLLMQLIATAAFVLLTMMPTVALLTSLVLFLLTILEVAVAMIQAYVFVLLLSLYLQENV", "output": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane."}]}
+{"id": "function_test_1579", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQHTVDIQAIESKLNFTFSHPRLLITALTHPSYRNEFPSAEEDSERLEFLGDAVLGLVVTEHLFLLFPALNEGLLSTTRAALVNAEACFEYTQKLSLGEHLLIGRGEKMQSHRGKISAYANLLEAILGAVYLDGGLSPARQIIVPLLPDKESILPLMLVNPKNRLQQFTQQTLKVLPSYKALPWKSEDGSPGYHVQVFVNGDLWGEGFAGSKKEAEKLAAKQALSTHDNKN", "output": "Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism."}]}
+{"id": "function_test_1580", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSRVGKKPIEIPAGVTVTVNGNTVTVKGPKGELTRTFHPDMTITVEGNVITVTRPSDEKHHRALHGTTRSLLANMVEGVSKGYEKALELVGVGYRASKQGKKLVLSVGYSHPVEIEPEEGLEIEVPSQTKIIVKGADKQRVGELAANIRAVRPPEPYKGKGIRYEGELVRLKEGKTGK", "output": "It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity). This protein binds to the 23S rRNA, and is important in its secondary structure."}]}
+{"id": "function_test_1581", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MARDDPHFNFRMPMEVREKLKFRAEANGRSMNSELLQIVQDALSKPSPVTGYRNDAERLADEQSELVKKMVFDTLKDLYKKTT", "output": "Mnt acts as a transcriptional repressor of genes ant and arc."}]}
+{"id": "function_test_1582", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEIRAAEISAILKEQIANFGTEAESAEVGQVLSVGDGIARVYGLDNVQAGEMVEFANGVKGMALNLESDNVGIVIFGEDRGIKEGDVVKRTQTIVDVPVGKGLLGRVVDGLGNPIDGKGDLVDVERKRAEVKAPGIIPRKSVHEPVQTGIKAIDSLIPIGRGQRELIIGDRQTGKTAVILDTILNQKAVNDKAKDDSEKLFCVYVAVGQKRSTVAQVVKVLADHGALDYTIVVAATASEPAPLQFLAPYTGCTMGEFFRDNGMHAVIFYDDLTKQAVAYRQMSLLLRRPPGREAFPGDVFYLHSRLLERAAKLNDDNGAGSLTALPVIETQANDVSAYIPTNVISITDGQIFLETDLFFKGIRPAVNVGLSVSRVGSSAQIKAMKQVAGSIKLELAQYREMAAFAQFASDLDPATQKLLARGARLTELLKQAQYSPLAVEEQVCVIYAGTRGYLDKLKTTDVVRYEASLLGALRTSGADLLESIRTGKALSKEIEQKLVKFLDDFGKKFA", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit."}]}
+{"id": "function_test_1583", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MCGIVGIVGHKPVSERLIEALGRLEYRGYDSSGVATIFEGELHRRRAEGKLGNLKTRLKEAPLSGTVGIAHTRWATHGAPTECNAHPHFTDGVAVVHNGIIENFSKLKDALAEVGTKFQTDTDTEVIAHLLTKFRRDGMGCLEAMHAMLKCVEGAFALAILFEDDPATIMVARNGPPLVIGHGDGEMFLGSDAIALAPFTNDITYLNDGDWAVVGKTSVQVFDIEGNVVTRPRHISLATADLVGKGNHPHFMEKEIYEQPEVIARALGHYINVNDSHVTTTSTDIDFAGVESLAISACGTAYLAGLIGKYWFERYARLIVEIDVASEFRYREIPLSPRSAALFISQSGETADTLASLRYCKAHGLRIGAVVNTRESTMAREADAIFPILAGPEIGVASTKAFTCQLAVLAALRIGAGKARGTITDDEEQVLVQSLATLPGVMRQVLNDITPEIELLSRELSHYRDVLYLGRGTSFPLAMEGALKLKEVSYIHAEGYAAGELKHGPIALIDENMPVIVIAPHDRFFDKTVSNMQEVAARGGRIILITDETGASMSKLPTMHTIVLPDVAEIIAPMIFSLPLQLLAYHTAVVMGADVDQPRNLAKSVTVE", "output": "Involved in the production of the root hair deformation (HAD) factor specifically on medicago."}]}
+{"id": "function_test_1584", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEDAKNIKKGPAPFYPLEDGTAGEQLHKAMKRYALVPGTIAFTDAHIEVNITYAEYFEMSVRLAEAMKRYGLNTNHRIVVCSENSLQFFMPVLGALFIGVAVAPANDIYNERELLNSMNISQPTVVFVSKKGLQKILNVQKKLPIIQKIIIMDSKTDYQGFQSMYTFVTSHLPPGFNEYDFVPESFDRDKTIALIMNSSGSTGLPKGVALPHRTACVRFSHARDPIFGNQIIPDTAILSVVPFHHGFGMFTTLGYLICGFRVVLMYRFEEELFLRSLQDYKIQSALLVPTLFSFFAKSTLIDKYDLSNLHEIASGGAPLSKEVGEAVAKRFHLPGIRQGYGLTETTSAILITPEGDDKPGAVGKVVPFFEAKVVDLDTGKTLGVNQRGELCVRGPMIMSGYVNNPEATNALIDKDGWLHSGDIAYWDEDEHFFIVDRLKSLIKYKGYQVAPAELESILLQHPNIFDAGVAGLPDDDAGELPAAVVVLEHGKTMTEKEIVDYVASQVTTAKKLRGGVVFVDEVPKGLTGKLDARKIREILIKAKKGGKSKL", "output": "Produces green light with a wavelength of 562 nm."}]}
+{"id": "function_test_1585", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLTEGISIQSYDGHTFGALVGSPAKAPAPVIVIAQEIFGVNAFMRETVSWLVDQGYAAVCPDLYARQAPGTALDPQDERQREQAYKLWQAFDMEAGVGDLEAAIRYARHQPYSNGKVGLVGYCLGGALAFLVAAKGYVDRAVGYYGVGLEKQLKKVPEVKHPALFHMGGQDHFVPAPSRQLITEGFGANPLLQVHWYEEAGHSFARTSSSGYVASAAALANERRLDFLAPLQSKKP", "output": "Ring cleavage of cyclic ester dienelactone to produce maleylacetate."}]}
+{"id": "function_test_1586", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKLPIYLDYSATTPVDPRVAEKMMQFMTMDGTFGNPASRSHRFGWQAEEAVDIARNQIADLVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKTEHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLKELEAAMRDDTILVSIMHVNNEIGVVQDIAAIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIYGPKGIGALYVRRKPRVRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMATEMERLRGLRNRLWNGIKDIEEVYLNGDLEHGAPNILNVSFNYVEGESLIMALKDLAVSSGSACTSASLEPSYVLRALGLNDELAHSSIRFSLGRFTTEEEIDYTIELVRKSIGRLRDLSPLWEMYKQGVDLNSIEWAHH", "output": "Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur and selenium atoms from cysteine and selenocysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. Also functions as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate."}]}
+{"id": "function_test_1587", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTDKLTSLRQYTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVAWAKQQSNDRAQQIVDATDKLAVNIGLEILKLVPGRISTEVDARLSYDTEASIAKAKRLIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVSEIYQYYKEHGYETVVMGASFRNIGEILELAGCDRLTIAPALLKELAESEGAIERKLSYTGEVKARPARITESEFLWQHNQDPMAVDKLAEGIRKFAIDQEKLEKMIGDLL", "output": "Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway."}]}
+{"id": "function_test_1588", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGKVLRKPFAKAVPLLFLAATWLLTGVLPAGASSPTNAAAASLTEAQDQFYSYTCNADTFSPSLTSFASIWALLTLVLVIIASAIYLMYVCFNKFVNTLLTD", "output": "Envelope glycoprotein necessary for proper maturation of gM and modulation of its membrane fusion activity. Also plays a critical role in virion morphogenesis."}]}
+{"id": "function_test_1589", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRLLILFLAVVTLLSLAGPGSAEVRRRRRRPPCEDVNGQCQPRGNPCLRLRGACPRGSRCCMPTVAAH", "output": "Potent antimicrobial peptide that displays activity against S.aureus and P.aeruginosa . Does not inhibit growth of E.coli ."}]}
+{"id": "function_test_1590", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "WCSTCLDLACGASRECYDPCFKAFGRAHGKCMNNKCRCYT", "output": "Inhibits high conductance calcium-activated potassium channels. Reversibly inhibits Shaker B potassium channels (By similarity)."}]}
+{"id": "function_test_1591", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPYGTRYPTLAFHTGGVGESDDGMPPQPFETFCYDSALLQAKIENFNIVPYTSVLPKELFGNILPVDQCTKFFKHGAVLEVIMAGRGATVTDGTQAIATGVGICWGKDKNGELIGGWAAEYVEFFPTWIDDEIAESHAKMWLKKSLQHELDLRSVSKHSEFQYFHNYINIRKKFGFCLTALGFLNFENAAPAVIQ", "output": "Part of the AaxABC system, catalyzes the decarboxylation of L-arginine. The arginine uptake by the bacterium in the macrophage may be a virulence factor against the host innate immune response (By similarity)."}]}
+{"id": "function_test_1592", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTDTIFALATAAGRSAVAVVRVSGPRSSEIAAALCGRLPSPRLASVRTLKHNGVALDAALVLRFEKPASYTGEDSVEFHVHGGRAVVEALLAALSELGARLAEAGEFTRRAFENGKLDLAQAEGVADLIDAETEAQRRQALGQVGGALSQRYDRWRDLLVQALAMLEAAVDFPDEDLPEEVAERARPGLRQLSAELNAALADVSRGRRVRDGFRIALIGAPNAGKSTLLNGLAERDAAIVTDVAGTTRDVIEVPLVLGGYKVLVADTAGIRETADVIEAEGVRRAKAWAEAADLRLWVVDGFHVKQADARPEAIRVGDWLILNKTDIADADASAHVAERWAGEGLTVLHIAGTSAEGPEALRAALASHVADALSGAEFPAATRLRHAERLSEARSYLERALSDVGLEVELAAEDVRLAARALERISGRIDPEDVLGRVFSTFCIGK", "output": "Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34."}]}
+{"id": "function_test_1593", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "HLLQFNKMIKFETGKNAIPFYAF", "output": "Snake venom phospholipase A2 (PLA2) that shows presynaptic neurotoxicity. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides."}]}
+{"id": "function_test_1594", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNKALFLCLVVLCAAVVFAAEDLQKAKHAPFKRAAPCFCSGKPGRGDLWILRGTCPGGYGYTSNCYKWPNICCYPH", "output": "Acts as a gating modifier on both Kv and Nav ion channels, and also acts on blood pressure (By similarity). Voltage-dependently inhibits voltage-gated potassium channels Kv3 (Kv3.1/KCNC1, Kv3.2/KCNC2 and Kv3.4/KCNC4) and slows inactivation of the voltage-gated sodium channel Nav1.7/SCN9A (By similarity). Inhibits all Kv3.1, Kv3.2 and Kv3.4 by about 50% when tested at a voltage of +40 mV (45%, 48% and 56%, respectively) (By similarity). May act by binding residues in voltage-sensing domains S3b and S4 of Kv3 (By similarity). On sodium channels, tests have been done on human Nav1.7/SCN9A (expressed in HEK293 cells) (EC(50)=3 nM) and rat SCG neurons that mostly carry Nav1.7 channels (EC(50)=300 nM) (By similarity). This toxin also reduces blood pressure (By similarity)."}]}
+{"id": "function_test_1595", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLTDPIADMLTRIRNATRVYKESTDVPASRFKEEILRILAREGFIKGYERVDVDGKPYLRVYLKYGPRRQGPDPRPEQVIHHIRRISKPGRRVYVGVKEIPRVRRGLGIAILSTSKGVLTDREARKLGVGGELICEVW", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit central domain. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit."}]}
+{"id": "function_test_1596", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGRIIFYEDKNFQGRRYECDSDCSDFHAFLNRCNSIRVESGAWVIYERPNFMGYQYVLTRGEYPDYQRWMGLNDRLCSCKMIHFVSGSEYKIQLYDKGDFTGQVYESTEDCPSVVDRFRTREVHSCKVLDGIWIFYEHPNYRGRQYLLEKGEYRKPVDWGAVCPTVQSFKRLME", "output": "Crystallins are the dominant structural components of the vertebrate eye lens."}]}
+{"id": "function_test_1597", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MATTRFPSLLFYSCIFLLCNGSMAQLFGQSFTPWQSSRQGGLRGCKFDRLQAFEPLRQVRSQAGITEYFDEQNEQFRCAGVSVIRRVIEPQGLLLPQYHNAPGLVYILQGRGFTGLTFPGCPATFQQQFQQFDQARFAQGQSKSQNLKDEHQRVHHIKQGDVVALPAGIVHWCYNDGDAPIVAVYVFDVNNNANQLEPRQKEFLLAGNNKREQQFGQNIFSGFSVQLLSEALGISQQAAQKIQSQNDQRGEIIRVSQGLQFLKPFVSQQGPVEHQAYQPIQSQQEQSTQYQVGQSPQYQEGQSTQYQSGQSWDQSFNGLEENFCSLEARQNIENPKRADTYNPRAGRITHLNSKNFPTLNLVQMSATRVNLYQNAILSPYWNINAHSVMHMIQGRARVQVVNNHGQTVFNDILRRGQLLIIPQHYVVLKKAEREGCQYISFKTTPNSMVSYIAGKTSILRALPVDVLANAYRISRQESQNLKNNRGEEFGAFTPKFAQTGSQSYQDEGESSSTEKASE", "output": "This is a seed storage protein."}]}
+{"id": "function_test_1598", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKDVLDDNLLEEPAAQYSLFEPESNPNLREKFTFIDLFAGIGGFRIAMQNLGGKCIFSSEWDEQAQKTYEANFGDLPYGDITLEETKAFIPEKFDILCAGFPCQAFSIAGKRGGFEDTRGTLFFDVAEIIRRHQPKAFFLENVKGLKNHDKGRTLKTILNVLREDLGYFVPEPAIVNAKNFGVPQNRERIYIVGFHKSTGVNSFSYPEPLDKIVTFADIREEKTVPTKYYLSTQYIDTLRKHKERHESKGNGFGYEIIPDDGIANAIVVGGMGRERNLVIDHRITDFTPTTNIKGEVNREGIRKMTPREWARLQGFPDSYVIPVSDASAYKQFGNSVAVPAIQATGKKILEKLGNLYD", "output": "A methylase that recognizes the double-stranded sequence 5'-CCGG-3', methylates C-2 on both strands, and protects the DNA from cleavage by the HpaII endonuclease."}]}
+{"id": "function_test_1599", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MYPSRNKRGSYFNQRRQYSRNHVWKRPTAAKRHDWKRRPSNTSKPNDEPKMSAQRIHENQYGPEFVMAQNSAISSFISYPDLGRSEPNRSRSYIRLKQLRFKGTVKIEQVPLAMNMDGSTPKVEGVFSLVIVVDRKPHLGPSGCLHTFDELFGARIHSHGNLSVTPALKDRYYIRHVCKRVLSVEKDTLMVDVEGSIPLSNRRINCWATFKDVDRESCKGVYDNISKNALLVYYCWMSDTPAKASTFVSFDLDYIG", "output": "Binds to the genomic viral ssDNA, shuttles it into and out of the cell nucleus. Begomoviruses use 2 proteins to transport their DNA from cell to cell. The nuclear shuttle protein (NSP) shuttles it between nucleus and cytoplasm and the movement protein (MP) probably transports the DNA-NSP complex to the cell periphery and facilitates movement across the cell wall."}]}
+{"id": "function_test_1600", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNKKVLTLSAVMASLLFGAHAHAADTRIGVTIYKYDDNFMSVVRKAIEKDGKSAPDVQLLMNDSQNDQSKQNDQIDVLLAKGVKALAINLVDPAAAGTVIEKARGQNVPVVFFNKEPSRKALDSYDKAYYVGTDSKESGVIQGDLIAKHWQANQGWDLNKDGKIQYVLLKGEPGHPDAEARTTYVVKELNDKGIQTEQLALDTAMWDTAQAKDKMDAWLSGPNANKIEVVIANNDAMAMGAVEALKAHNKSSIPVFGVDALPEALALVKSGAMAGTVLNDANNQAKATFDLAKNLAEGKGAADGTSWKIENKIVRVPYVGVDKDNLSEFTQK", "output": "Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import (By similarity). In addition, binds D-galactose and D-glucose and plays a role in the chemotaxis towards these two sugars by interacting with the Trg chemoreceptor (Probable)."}]}
+{"id": "function_test_1601", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLDRVVVLLSVLCLGVSSQPIPNNQHLFSMAVSRIHHLHLRAQRLFANFESSLQSDDQRQLNKIFLQDFCNSDYIISPIDKHETQRSSVLKLLLISKQLVESWEISSHFLPGGLAERSQISSRLAELREGIQMLITTNQEGAEVFSDSSTLPLAPPFGNFFQTQGGDELQRRSYELLACFKKDMHKVETYLTVAKCRLSTEANCTL", "output": "Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes. Implicated as an osmoregulatory substance important for seawater adaptation."}]}
+{"id": "function_test_1602", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MYMDRHCVYYRKPLLESGTLGTKGNIQVVIPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFESLFKQPAENVNQYLTNPKFVERTLRLGGTQPLEVLEAVHRSLVLQRPHDWADCVTWACLHWHSQYANNIRQLLHNFPPEQ", "output": "Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP (By similarity). The Y chromosome form could be involved in the survival and proliferation of differentiating spermatogonia."}]}
+{"id": "function_test_1603", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTNQLFDAYFTAPAMREIFSDRGRLQGMLDFEAALARAEAAAGLVPHSAVAAIEAACKAERYDVGALANAIATAGNSAIPLVKALGKVIASGVPEAERYVHLGATSQDAMDTGLVLQLRDALDLIEADLGKLADTLSQQALKHADTPMVGRTWLQHATPVTLGMKLAGVLGALTRHRQRLQELGPPCWCCSSGGASGSLAALGSKAMPVAEALAEQLKLSLPEQPWHTQRDRLVEFASVLGLVAGSLGKFGRDVSLLMQTEAGEVFEPSAPGKGGSSTMPHKRNPVGAAVLIGAATRVPGLVSTLFAAMPQEHERSLGLWHAEWETLPDICCLVSGALRQAQVIAEGIEVDAARMRRNLDLTQGLVLAEAVSIVLARTLGRDRAHHLLEQCCQRAVAEQRHLRAVLGDDPQVSAELSAEELD", "output": "Catalyzes an anti cycloisomerization."}]}
+{"id": "function_test_1604", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKLLLLLALLVGAVSTRHLNVDTSSLQSLQGEESLAQDGETAEGATREAASGVLMPLREEVKEEMEGGSGSEDDPEEEEEEKEMESSSELDMGPEDVQCPKEEDIVKFEGSPGCKICRYVVLSVPKTFKQAQSVCQRCFRGNLASIHSYNINLQVQRSSRILNVAQVWIGGQLRGKGHHKHFHWVDGTLWNFWYWAAGQPWRGNNSGRCVTLCARGGHWRRSHCGVRRAFSCSY", "output": "MBP may play some important roles in the allergic reactions and inflammations, since MBP is capable of releasing histamine from mast cells and damaging the epithelial cells of bronchial tubes. Antiparasitic and antibiotic."}]}
+{"id": "function_test_1605", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDLLLLEKTLLALFIAATIAVTISKLRGKRFKLPPGPIPVPIFGYWLQVGDDLNHRNLTDYAKRFGEIFLLRMGQRNLVVVSSPELAKEVLHTQCVEFGSRTRNVVFDIFTGKGQDMVFTVYGEHWRKMRRIMTVPFFTNKVVQQYRYGWESEAESVVNDVKNNAEASVGGIVIRKRLQLMMYNIMYRIMFDRRFESEEDPLFVKLKALNGERSRLAQSFEYNYGDFIPILRPFLKGYLKVCKEVKDRRLQLFKDYFVDERKKLESTKSTTSNDGLKCAIDHILDAQKKGEINDDNVLYIVENINVAAIETTLWSIEWGIAELVNHQDIQNKVREEMDRVLGPGHQVTEPDLHKLPYLQAVIKETLRLRMAIPLLVPHMNLHDPKLNGFDIPAESKILVNAWWLPNNPAHWKKPEEFRPERFLEEESHVEANGNDFRYLPFGVGRRSCPGIILALPILGITIGRLVQNVELLPPPGQSKIDTSEKGGQFSLHILKHSTIVAKPRSF", "output": "Catalyzes the first oxidative step of the phenylpropanoid pathway in higher plants by transforming trans-cinnamate into p-coumarate (By similarity). The compounds formed by this pathway are essential components for lignification, pollination, and defense against ultraviolet light, predators and pathogens (By similarity)."}]}
+{"id": "function_test_1606", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MASLLKSLALFKKNKDKPPLAAGSGGAIRGIKHVIIVPIPGDSSITTRSRLLDCLVKMVGDPDISGPKLTGALISILSLFVESPGQLIQRITDDPDISIKLVEVIQSDKTQSGLTFASRGASMDDEADRYFTYDEPNGGEERQSYWFENREIQDIEVQDPEGFNMILATILAQIWILLAKAVTTPDTAADSELRRWVKYTQQRRVIGEFRLDKGWLDTVRNRIAEDLSLRRFMVALILDIKRTPGNKPRIAEMICDIDTYIVEAGLASFILTIKFGIETMYPALGLHEFAGELSTIESLMNLYQQMGELAPYMVILENSIQNKFSAGAYPLLWSYAMGVGVELESSMGGLNFGRSYFDPAYFRLGQEMVRRSAGKVSSNLASELGITEEEAKLVSEIAAYTGDDRNSRTSGPKQTQVSFLRTDQGGEIQHNASKKDEARVLQVRKETWASSRSDRYKEDTDNEAVSPSVKTLIDVDTTPEADTDPLGNKKSAEALLKLQAMASILEDPTLGNDSPRTYNDKDLLS", "output": "Encapsidates the genome in a ratio of 1 N per 6 ribonucleotides, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases."}]}
+{"id": "function_test_1607", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTEQFDKTYCGFIAIVGRPNVGKSTLLNKILGQKISITSRKAQTTRHRIVGIKTEGAYQEIYVDTPGLHIEEKRAINRLMNRAASSAIGDVDLIIFVVDGTHWNADDEMVLNKLRNAKAPVVLAINKVDNIKNKDDLLPFITDLSSKFNFAHIVPISAQRGNNVHELEKIVRQSLREGVHHFPEDYVTDRSQRFMASEIIREKLMRFTGEELPYSVTVEIEQFKVNERGTYEINGLILVEREGQKKMVIGAGGQKIKTIGMEARADMERLFDNKVHLELWVKVKSGWADDERALRSLGYMDE", "output": "An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism."}]}
+{"id": "function_test_1608", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLKGIHPALSPELLKTLAEMGHGDEIVLADAHFPAHSLHKNVIRADGISIDILLEAITPLFEFDAYVDAPLLMMKAVEGDSLDPNVETRYLNAIESAVGFTPNLTCLERFDFYTRAKQAYAVVVSGEIAKYGNIIIKKGVTPIL", "output": "Involved in the anomeric conversion of L-fucose."}]}
+{"id": "function_test_1609", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "KSEQSSFSSSSSVRNELSVYHNSRQKPPAEKTNQSSKNIGKKAAPFKKQKRANKGSSGAQVLYAKDSGGAQNESLRSNEADLAKKKNPNPSGDTGSSKNQDSMAAQNVHQKSQMSVETCTTPSKSNLILESLGLQFFGREVTLFRLKNYLTSERHSDVDDNVVQENLNDSRGEIPDSTPESKMHHKLVLPSYTPNVRRTMRTRSKPLEYWRGERIDYQARPSGGFVIGGILSPDTVSSKRKAKGNLGRIITTANRKRICLENAPIKNKFMVNLNIPLGDPLQPTRVKDPETQETVLMDLIRPRDTYQFCVEHDELKVYKTLDTPFFSSGKLIIGPLQEKGKQHVGLDTLVFYVNLGYLLCTLHETPYIVTTGDSFYVPSGNYYNIKNLLNEERVLLFTQIKS", "output": "Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions."}]}
+{"id": "function_test_1610", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKTPIYLDYAATTPVEFEVAKKMMNYLTIDGVFGNSASRSHKFGWKAEEVVDIARNQISELIGADSREIVFTSGATESNNLAIKGIASFHQNKGKHIVTSKTEHKSVLDTCRYLENKGFTVTYLTPKNNGIIDLNNLKKNIKKDTILVSIMHVNNEIGIIQDINSISQICRNHGVFFHVDATQSVGKIPIDLKKIPIDLMSFSAHKIYGPKGIGGLYVRRKPRVRLLSLIHGGGHERGMRSGTLPVHQIVGMGESFVLAKRKIHDDFIHLTKLKNILWNGIKNIEEVYLNSDLQQGAPHILNVSFNYVEGESLIMALKDLAISSGSACTSASLEPSYVLKSLGIRDELAHSSIRFSIGRFTTEKEIIHAIKLVHKSIHRLRELSPLWEMFKSGVDLNSIEWDHV", "output": "Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins."}]}
+{"id": "function_test_1611", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAAAVHGALKAVGEDFYRDAIEHCRSYNARLSAERSTRLPFLDAQTGVAQSDCYIWMERSHRGPGLSPGQIYSYPARCWRKKRRLNILEDPRLRPLCDAPQKKELGSAVAEGAVLEALLCAEPPKEPKEEEALLDCQKPPPGDFAHDAEGDEMEDDAPRRKNKAKGKTYGLGAVRKRQDAAALEDRDKPYVCDICGKRYKNRPGLSYHYTHTHLAEEEGEESAERHPLPFQRRNHHKQFYKELNWVPESQRRHAAAAGRRSEGPCDFCVGGAVRRAALGHEEMIACADCGRAGHPSCLQFTLAMAAAARSYRWQCIECKNCSLCGSAENDEQLLFCDDCDRGYHMYCISPPVAEPPEGTWSCHLCLRQLKDKAAAFITLT", "output": "May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex) and plays a role in neural development."}]}
+{"id": "function_test_1612", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGYKCTRCKQKVEIDYEYTGIRCPYCGHRILVKERPTTIKRIKAE", "output": "DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_1613", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTVTVSQVLRPRGPQIERLTENRAKVVLEPLGRGYAHTLGNALRRVLLSSIPGFAITEVEIDGVLHEYTTVEGLQEDVLEVLLNLKDVAIRIHSGDTATLSLFKQGAGVVTAADIKTDHNVEIINDGHVICHLTKDTTINMRLKIERGFGYQPAVVRRRPDDENRTIGRLILDASFSPVRRVAYVVEAARVEQRTDLDKLIIDIETNGTIDAEEALRTAADILTDQLSVFGDFTHRDRGTVKPASSGVDPVLLRPIDDLELTVRSANCLKAESIYYIGDLIQKTEVELLKTPNLGKKSLTEIKEVLGQRGLGLGVKLENWPPPGVSQYGMLG", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_1614", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDNKTYEISSAEWEVMNIIWMKKYASANNIIEEIQMQKDWSPKTIRTLITRLYKKGFIDRKKDNKIFQYYSLVEESDIKYKTSKNFINKVYKGGFNSLVLNFVEKEDLSQDEIEELRNILNKK", "output": "Transcriptional repressor that constitutively blocks the transcription of the gene for the penicillin-binding protein MecA. Binds palindromic DNA with the sequence 5'-TACA-[AT]-N-TGTA-3'. Regulates genes involved in antibiotic resistance. Binds DNA as a dimer."}]}
+{"id": "function_test_1615", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "TALFLAMHYTSDIATAFSSVAHICRDVNYGWLIRNMHANGASFFFICIYLHIGRGLYYGSYLYKETWNVGVVLLLLTMM", "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."}]}
+{"id": "function_test_1616", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDLILCHQTADFDVLGAAVGLAKLHPGSRIVLTGGSHPTVRQFLALHRNEFPLIELRSVNPDKIRSLYIVDNQQGDRLGKAADWLTLPHLRQVAIYDHHLNSPRDIEADIWELEAVGASTTLIVEKLQRADISLSMVEASVMALGIHVDTGSLTFTQTTVRDVKALAWLMEQGANLRLIAEYADPGFPPPLQFLFAEAMQNLHKEMVRGYWLGSVLLTTENFVPGLSHLTERLLSLTECDALLLGHVYDKGKDKTKNDEQREKTGVISNQRFSLIGRTRIPDTDLTQLLEPYGGGGHAQAAAVNLRDVEPTTVMAEIYQALQRQIPKPLLARDFMSSPVRTIRPHTTIEQAQRVLFRYGHSGLTVVNQEEKLVGIISRRDLDLALHHGFSHAPVKGYMTRNVKTIAPDTPLPRIEAIMVADDVGRLPVMDQEKLVGIVTRTDVLRQLLQDKQEQSGRFGAPRSGSLRDRPTTPNQNFGQGSLLQLLKTHLPPATWQLLTTAAQQAQTRGWHLYLVGGAVRDLWLRHSQGAEKHQNITFQDIDLVVDGFHATADVGAGVELAQALQGDYPGARLSVHGEFQTAALLWHKDPQLDTLWVDIATARTEFYPYPAANPEVEASSIRQDLYRRDFTINALSIRLTNPNPGKLLDFFGGMNDLQSQQVRVLHANSFIEDPTRIYRAVRFVVRLGFELEPQTETYIRYAIASGVYERWRLTEHPTPALTTRLKAELSIILKAPYWKGALTLLADLDALKCLHAELKLTEQLWWQVRYLSRWLRWFDPERNLEHWLLRLGILLGALPPQEREKIAAGLQLPKATIDGLTNLETIETAIAKGLNSPASPKSSPKSSVIYQTLKDYDRFSLFLVAARGNKLLRKQIWFYFSQLCQVSPFLTGHDLKALGYKPGPQFKQILTDLLNACLDGELGDRQQEEAWLRTHYPLPNKV", "output": "tRNA nucleotidyltransferase involved in the synthesis of the tRNA CCA terminus. Adds the terminal adenosine residue to tRNA . Acts as a nucleotidyltransferase and not a poly(A) polymerase ."}]}
+{"id": "function_test_1617", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNAASAIALLIVFSLVIGYLMGSVMFADVFGKILNKDVRKLGSKNPGATNSIRVFGLKIGFLVGLCDALKGFLAFVFSFLIFSFWLQQYLNVNQYQKVYYLTYLSCFAATIGHIFPLYFKFKGGKAIATTGGSLLAISLWWFVICLVLWLLVTLITKYVSLASLVTFFILAIIILVPWLDYLYFFKPNPINAISYQNDWYIILFFVLWYWPLTIAVFWLHRKNIHRLLNKTENKVTQLN", "output": "Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP."}]}
+{"id": "function_test_1618", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "AVPDKIDRRESGYV", "output": "Thiol protease that assists the parasite in burrowing through the gut wall and liver of its mammalian host."}]}
+{"id": "function_test_1619", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "LAKTNFPLNFPIHVRDAGVQWSPLGRLTTGADVRHEIPARVGHRLARWA", "output": "Beta-galactoside specific lectin. Has a hemagglutinating activity on erythrocytes."}]}
+{"id": "function_test_1620", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "GLWSKIKETGKEAAKAAGKAALNKIAEAV", "output": "Antimicrobial peptide, active against the Gram-positive bacterium S.aureus, the Gram-negative bacteria E.coli and P.aeruginosa, and the yeasts C.albicans and P.brasiliensis. Has hemolytic activity (40% hemolysis at 128 ug/ml)."}]}
+{"id": "function_test_1621", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "QDLDHVFMRF", "output": "Myoinhibiting neuropeptide."}]}
+{"id": "function_test_1622", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAEGGSSEEELRAIVHNLGVSPFFLGTFDKRFPGFISSQRMACAIVNTAGRETGGVHWLAMAWNPRSKTFYMFDPFGFSDSKLKQVYSFEYEGLLRRSAIASSPDRCVTLAKSNETIQGPNSAACGLFCCMFLHAFVNWPDDPFDHNPTMGPLKSVPNYKLNDPTVQYVLWGNQEKLYKFLEKHSAYFRAHAAAIKARTAFNKLKQ", "output": "Cleaves viral precursor proteins (pTP, pIIIa, pVI, pVII, pVIII, and pX) inside newly assembled particles giving rise to mature virions. Protease complexed to its cofactor slides along the viral DNA to specifically locate and cleave the viral precursors. Mature virions have a weakened organization compared to the unmature virions, thereby facilitating subsequent uncoating. Without maturation, the particle lacks infectivity and is unable to uncoat. Late in adenovirus infection, in the cytoplasm, may participate in the cytoskeleton destruction. Cleaves host cell cytoskeletal keratins K7 and K18."}]}
+{"id": "function_test_1623", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MALNLRKNHPLMKIINDSLIDLPTPSNISVWWNFGSLLGICLVTQIVTGLLLSMHYTADTSLAFASVSHMCRNVQFGWLIRNLHANGASLFFICIYLHIGRGLYYGSYLNKETWNIGVILLLTLMATVFVGYVLPWGQMSSWGATVITNLFSAIPYIGQTLVEWLWGGFSVDNPTLTRFFAFHFLLPFVIAGLTLVHLTFLHETGSNNPLGIPSDCDKIPFHPYYSIKDLLGFVLMLIVLVTLALFNPYMLGDPENFTPDKPLATPPHIKPEWYFLFAYAILRSIPNKLGGVLALAASVLILFLIPLLHTSKQRSMTFRPLSQILWWTLVADLLILTWVGSQPVEHPFIIIGQLASFAYFTIILILFPIASALENKMLNL", "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."}]}
+{"id": "function_test_1624", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAPDIDNIWSSTTDAAESPVDERRILLKRAVGQKILVPSILSLMPAWPSQVHPAVDEVNTEIDKWLPTVNVAEKKKAKHRARGNYAFLTAVYYPYCKETERLVVIAKFLYWIFFWDDEIDTGGELTEDEEGTIQCCEETNKCVDDCLGPNPNYNPPPNSRGTVEMFYPILRDFRAGLGPVSTERLRLELHDYINGVAKQQKVRQGERLPDPWYHFKIRSDDVGVIPSITQNEYAMKFELPEYVRRHEAMEEIVQECTKLTVLLNDVLSLQKEFRDSQLENLVLLFMNRYNLSLQAAVDKVLDLIREHYAICVAAEKRLPWSEDDEKLNDDIREYVRGCQRLATGTAYWSYSCERYFKQTQVNDKWEVLLDLSYVE", "output": "Terpene cyclase; part of the gene cluster that mediates the biosynthesis of the brasilane terpene glycosides brasilane D and E . The biosynthesis starts with the activity of the terpene cyclase braA that converts farnesyl pyrophosphate into the sesquiterpene alcohol trichobrasilenol . Subsequently, trichobrasilenol is glycosylated by the O-glycosyltransferase braB putatively using UDP-GlcNAc as sugar donor to yield brasilane A . The latter then undergoes two rounds of oxidation performed by the cytochrome P450 monooxygenase braC . In the first round braC hydroxylates C-12 forming brasilane D, which serves as substrate in the second round to establish the epoxide at the bond between C-5 and C-10 and oxidize the alcohol at C-12 to an aldehyde leading to the final product brasilane E ."}]}
+{"id": "function_test_1625", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTAQNPNLAALSAAGVSVWLDDLSRDRLRSGNLQELIDTKSVVGVTTNPSIFQKALSEGHTYDAQIAELAARGADVDATIRTVTTDDVRSACDVLVPQWEDSDGVDGRVSIEVDPRLAHETEKTIQQAIELWKIVDRPNLFIKIPATKAGLPAISAVLAEGISVNVTLIFSVQRYREVMDAYLTGMEKARQAGHSLSKIHSVASFFVSRVDTEIDKRLDRIGSRQALELRGQAGVANARLAYATYREVFEDSDRYRSLKVDGARVQRPLWASTGVKNPDYSDTLYVTELVAPHTVNTMPEKTIDAVADHGVIQGDTVTGTASDAQAVFDQLGAIGIDLTDVFAVLEEEGVRKFEASWNELLQETRAHLDTAAQ", "output": "Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway."}]}
+{"id": "function_test_1626", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MANEPAIGAIDRLQRSSRDVTTLPAVISRWLSSVLPGGAAPEVTVESGVDSTGMSSETIILTARWQQDGRSIQQKLVARVAPAAEDVPVFPTYRLDHQFEVIRLVGELTDVPVPRVRWIETTGDVLGTPFFLMDYVEGVVPPDVMPYTFGDNWFADAPAERQRQLQDATVAALATLHSIPNAQNTFSFLTQGRTSDTTLHRHFNWVRSWYDFAVEGIGRSPLLERTFEWLQSHWPDDAAAREPVLLWGDARVGNVLYRDFQPVAVLDWEMVALGPRELDVAWMIFAHRVFQELAGLATLPGLPEVMREDDVRATYQALTGVELGDLHWFYVYSGVMWACVFMRTGARRVHFGEIEKPDDVESLFYHAGLMKHLLGEEH", "output": "Might catalyze the phosphorylation of aminoglycosides and confer aminoglycoside antibiotics resistance."}]}
+{"id": "function_test_1627", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSPKTHTLSVLVEDKPGVLARVAALFSRRGFNIESLAVGATECKDRSRMTIVVSAEDTPLEQITKQLNKLINVIKIVEQDDEHSVSRELALIKVQADAGSRSQVIEAVNLFRANVIDVSPESLTVEATGNRGKLEALLRVLEPFGIREIAQSGMVSLSRGPRGIGTAK", "output": "Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine."}]}
+{"id": "function_test_1628", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPLILLPAVDVVEGRAVRLVQGKAGSQTEYGSAVDAALGWQRDGAEWIHLVDLDAAFGRGSNHELLAEVVGKLDVQVELSGGIRDDESLAAALATGCARVNVGTAALENPQWCARVIGEHGDQVAVGLDVQIIDGEHRLRGRGWETDGGDLWDVLERLDSEGCSRFVVTDITKDGTLGGPNLDLLAGVADRTDAPVIASGGVSSLDDLRAIATLTHRGVEGAIVGKALYARRFTLPQALAAVRD", "output": "Involved in both the histidine and tryptophan biosynthetic pathways."}]}
+{"id": "function_test_1629", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAATHLTSTSSLTINTLPSFEGLRSASGISKINVSVAYPSFTSRSFRGLVVRAASITTSKYTSVKPLGDRVLIKTKIVEEKTTSGIFLPTAAQKKPQSGEVVAIGSGKKVGDKKLPVAVKTGAEVVYSKYTGTEIEVDGSSHLIVKEDDIIGILETDDVKDLKPLNDRLLIKVAEVENKTSGGLLLAESSKEKPSFGTVVATGPGVLDEEGNRIPLPVCSGNTVLYSKYAGNDFKGVDGSDYMVLRVSDVMAVLS", "output": "Seems to function only as a co-chaperone, along with cpn60, and in certain cases is essential for the discharge of biologically active proteins from cpn60."}]}
+{"id": "function_test_1630", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRYNTAKLLVYDAEQVSKGIEKIQEHVENTEKYLSLYESTVINETDRIQLQELKALWEKYKSLVDKEVELVKSGKTEEARQLLLSDIDDIGDTLRDYFEAFVEYNTTAAKEKVDENKQVASTASTVMIVVIFVGILIAIALGVFISRIISKPIGQMVEAADRLALGDVEVDVKAETRDEIGKLAESFKRMIENIREQAYVVERIAAGDMTVDVRVKSDKDLLGKKLKEMVDTNNEVLSNINEVAAQVAAGAKQVSDSSMQLSQGATEQASSIEELTASLEQVANQTQLSAKNANQANELAEVAKNNAEQGNKQMAEMLNAMEEINNSSSNISRIIKVIDEIAFQTNILALNAAVEAARAGQHGKGFAVVAEEVRNLAARSANAAKETTELIEGTIKRTENGTKIARETAEALNKIVEGISKAATLVNDIAVASNEQAAAITQINQGIAQVSQVVQTNSATSEESAAASEELSSQAELLKRSIAKFKLKNMGKMTSNRYKEVSPEIMRMLEDYTENKQPKSYSKEENGEYSDGKETAEKDVGGLKQKILLSDSEFGKY", "output": "May bind attractants or detect changes in the extracellular concentration of soluble sugars."}]}
+{"id": "function_test_1631", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MVEPQEGKTRFHDFNLAPSLMHAIHDLGFPYCTPIQAQVLGFTLRGQDAIGRAQTGTGKTAAFLISIITQLLQTPPPKERYMGEPRALIIAPTRELVVQIAKDAAALTKYTGLNVMTFVGGMDFDKQLKQLEARFCDILVATPGRLLDFNQRGEVHLDMVEVMVLDEADRMLDMGFIPQVRQIIRQTPHKGERQTLLFSATFTDDVMNLAKQWTVDPAIVEIEPENVASDTVEQHVYAVAGSDKYKLLYNLVAQNNWERVMVFANRKDEVRRIEERLTKDGISAAQMSGDVPQHKRIRTLEGFREGKIRVLVATDVAGRGIHIDGISHVINFTLPEDPDDYVHRIGRTGRAGASGTSISFAGEDDAFALPPIEELLGRKITCEMPPAELLKPVPRKH", "output": "DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA."}]}
+{"id": "function_test_1632", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTEHAIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQATVKTMSPEELKTLGSGIILSNTYHLWLRPGDELVAEAGGLHKFMNWDQPILTDSGGFQVYSLVQNKKNITEEGVKFKSHLDGRELFLNPEKAISIQNNLGSDIMMSFDECPPFYQPYDYVKASVERTSRWAERGLNAHRRPNDQGLFGIVQGAGFEDLRRQSASDLTSMDFAGYSIGGLAVGESHKEMNAVLDFTTPMLPEDKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTRIARNGTLMTHFGRVNIRNAKYEHDFTPLDPMCDCYTCTNYTRAYLRHLIKADETFGLRLCSYHNLHFLVNLMKDVRQAIMDDNLLEFREDFCERYGYNQPNAKDF", "output": "Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)."}]}
+{"id": "function_test_1633", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRLDLTQPDFKAAIPILKKIEAAGYEAYFVGGSVRDAILGLPIHDVDIASSAYPAEIKRIFKRTADTGIEHGTVMVLDHGTGYEVTTFRTESRYQDFRRPDHVTFVRSLAEDLKRRDFTINALAVRHDGTIIDLFDGLKDLQHHQLRAVGNPHERFHEDALRMMRAVRFESQLGFGIEPATKAAIADNAKLLVHISVERVAAEFNRLLTGIDRRAGLQDFIETRLFAYAPKMAAHETALTQFSQLPDTQLTSLASGWAALIFLLRTQPLVMLKAWKQSNELITLVTQTVKLLQVMPNPTAWDLYQAGEAAVTTASEVQKLLTPDFDQQQLAEAYAALPIHSKKELALTGADLIKAGVRPGPAMGKALNQIEQRVVAGALPNELKKLLPIATEMSQDRL", "output": "Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate."}]}
+{"id": "function_test_1634", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSITKEFDTITAISTPLGEGAIGIVRLSGTDAIAIANKVFKGKNLETVDSHTINYGHIVENNEIIDEVMVSVMRAPKTFTREDVVEINTHGGVAVTNEILQLLIRSGARMAEPGEFTKRAFLNGRIDLTQAEAVMDLIRAKTDKAMTVAVSQLDGSLKNLINNTRQEILNTLAQVEVNIDYPEYDDVEEVTTNLVREKTQEFQALLENLLATAKRGKILREGLSTAIIGRPNVGKSSLLNNLLREEKAIVTDIEGTTRDVIEEYVNIKGVPLKLIDTAGIRDTDDVVEKIGVERSKKALEEADLVLLVLNSSEPLTDQDRTLLDISQNSNRIILLNKTDLPQAIQTEELPEDLIPISVLKNENIDKIEDRINQLFFDNAGLVEKDATYLSNARHISLIEKALESLEAVNQGLELGMPVDLLQVDMTRTWEILGEITGDAAPDELITQLFSQFCLGK", "output": "Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34."}]}
+{"id": "function_test_1635", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTVLPDDGLSLAAEFPDATHEQWHRLVEGVVRKSGKDVSGTAAEEALSTTLEDGLTTRPLYTARDAAPDAGFPGFAPFVRGSVPEGNTPGGWDVRQRYASADPARTNEAVLTDLENGVTSLWLTLGSAGLPVTGLERALDGVYLDLVPVALDAGSEAATAARELLRLYEAAGVADDAVRGTLGADPLGHEARTGEKSTSFAAVAELARLCGERYPGLRALTVDALPYHEAGASAAQELGASLATGVEYLRALHDKGLGVEKAFAQLEFRFAATADQFLTIAKLRAARRLWARVAEVSGVPAAGAQRQHAVTSPVMMTRRDPWVNMLRTTVACLGAGVGGADAVTVLPFDHELGLPDAFARRIARNTSTILLEESHLARVIDPAGGSWYVERLTDELAHAAWDFFKEIERADGQVAALRSGLVGDRIAATWAERRKKLARRREPITGVSEFPLLTERPVEREPAPAAPPGGLPRVRRDEAYEELRGRSDAHLEATGARPKVFIAALGPAAAHTARATFAANLFMAGGVEPVHDPVSVDAETAAEAFAASGATVACLCSSDVLYAEQAEAVARALKSAGALRVFLAGRGEFADIDEYVFAGCDAVAVLTSTLDRMGVA", "output": "Catalyzes the isomerization of succinyl-CoA to methylmalonyl-CoA during synthesis of propionate from tricarboxylic acid-cycle intermediates. This conversion most likely represents an important source of building blocks for polyketide antibiotic biosynthesis. It is unable to catalyze the conversion of isobutyryl-CoA into N-butyryl-CoA."}]}
+{"id": "function_test_1636", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSEQKLALNEYLKIDSDYLRGDIQEGLDTQVTGSFSDGDQQLIKFHGFYQQDDRDLRNERKEQKLEPLHSFMLRARVPGGICTPAQWLEVDKISSTLTTSNSIRLTTRQTFQYHGIPKRNLKTLIQGLDRAALDSIAACGDVNRNVMCNPNPVESKLHAQAYAVAKHLSDHLLPHTRAYAEIWLDEEKLLGTETVEPVYGKTYLPRKFKMAVAVPPHNDVDVYTNDLGFIAVSEAGELIGFNLVAGGGMGSTHGEVETFPRLADDFGFIKTDDVTKFAEAVMTVQRDWGNRVVRKRARLKYTIVDHGYDAFKAEVEKRAGVKFEPKRDVIIGDRGDRYGWVEGIDNKFHLTLFIESGRIKDMPGQTLQTGLREIAKIHKGDFRMTSNQNMIIAGVAAQDKAEIEGLARKHGLLGQVLSGTRGHSIACVALPTCPLAMAEAERYFPEFIDHIDALQAKHGISEQSIVVRMTGCPNGCARPFAAEIGLVGKAPGRYNLYLGASFEGTRLNKMHKENIQEAEILAELDTLFGRYATERDAGETFGNFTVRIGVVKAVNDAAKDFHA", "output": "Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate."}]}
+{"id": "function_test_1637", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTTKKRTASSTRWMQEHFDDHYVKLAQKRGLRSRAAFKLEEIQEKDHLIKQGMTVVDLGAAPGGWSQVAAKLTGDKGKVIACDILPMDPIVGVDFLQGDFREDKVLQALLERVGQDKVDVVLSDMAPNMSGSGAVDQPRAMYLVELALDMCHQVLTPNGCFAVKVFQGEGFDDYIKTVKQAFKVVKTRKPDSSRARSREVYLVATGYKL", "output": "Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit."}]}
+{"id": "function_test_1638", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAIQRTFSIIKPDATARNLTGAINAKIEAAGLRIIAQKRIRLSREQAEGFYGVHKERPFFNDLVTFMISGPVVVQVLEGEDAIAKYRTVMGATNPEQADAGTIRKDFAESIEANSVHGSDAPETAAEEIPFFFSDDEIVG", "output": "Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate."}]}
+{"id": "function_test_1639", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MFRLSSGLLKGGACASRSRIPQLGRSLYSTATSAGADKTQGKIHTVIGAVVDVQFNHGRLPPILNALETTNQGKKLVLEVAQHLGEHTVRCIAMDGTEGLVRGTAVADTGNPIMVPVGPATLGRIMNVTGDPIDERGPIEGVRLMPIHTEPPAYTEQSTHAEILVTGIKVVDLLAPYARGGKIGLFGGAGVGKTVFIQELINNIAKAHGGYSVFTGVGERTREGNDLYHEMQETGVIKLDGDSKVALVFGQMNEPPGARARVALTGLTIAEYFRDEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPTLAVDMGAMQERITTTTKGSITSVQAVYVPADDLTDPAPATTFIHLDATTELSRGISELGIYPAVDPLGSKSRLMDPRIVGEEHYDTAMRVQRTLQEYKSLQDIIAILAGVA", "output": "ATP synthase subunit beta; part of the gene cluster that mediates the biosynthesis of citreoviridin, an inhibitor of the of F1-ATPase beta-subunit . Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (By similarity). Whereas ctvA to ctvD constitute the core biosynthetic gene cluster, ctvE acts as a self-resistance gene ."}]}
+{"id": "function_test_1640", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDKTQSSQGKCPVMHGANSAVASNNMDWWPKALNLDILHQHDKKTDPMDPKFNYREAFNSLDLAAVKRDLNALMTDSQDWWPADWGHYGGLMIRMAWHSAGTYRVADGRGGAGTGNQRFAPLNSWPDNANLDKARRLLWPIKKKYGNKLSWADLMILAGNVAYESMGLKTYGFAGGREDIWHPEKDIYWGSEKQWLAPTENPNSRYSGERDLENPLAAVMMGLIYVNPEGVDGKPDPLRTAQDVRVTFARMAMNDEETVALTAGGHTVGKCHGNGKAQDLGPEPEGEELEAQGLGWLNKKGPGTGANAVTSGLEGAWTTHPTQWDNGYFHLLLNYDWELKKSPAGASQWEPINIKEEDKVVSVGDPNRKFNPIMTDADMAMKMDPEYRKISEKFYQDPAYFSEVFARAWFKLTHRDLGPKSRYLGPEVPNEDLLWQDPIPSVDYRLDASEIVDLKAKLLASGLSVSELVATAWDSARTFRGSDFRGGANGARIRLAPQKDWQANEPERLQKVLKVLTELQASLSKKVSIADLIVLGGAAAIEKAAHEAGVKVTVPFIPGRGDATQEMTDVESFAVLEPLHDAYRNWQKKDYVVQPEEMMLDRTQLMGLTAHEMTVLVGGMRVLGTNYGGTRHGVFTDKVGVLTNDFFVNLTDMAYNWKPAGSNLYQIVERKTGAVKWTASRVDLVFGSNSILRAYAEMYAQDDAKEKFVHDFVAAWTKVMNADRFDLA", "output": "Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity."}]}
+{"id": "function_test_1641", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTQLETRTEPMVVNFGPHHPSMHGVLRLVVTLDGEDVVDCEPVIGYLHRGMEKIAENRTNVMYVPYVSRMDYAAGMFYEAIVVNAPERLANIPVPKRASYIRVLMLELNRIANHLLWLGPFLADVGAQTPFFYIFREREMIYDLWEAATGQRLINNNYFRIGGVAADLPWGWLEKCKDFCDWFGPKIDEYEKLITNNPIFRRRIEGLGVIGREEAINWSLSGPMLRASGVPWDLRKVDHYECYDDFDWDVASEKEGDCFARYRVRIEEMRQSLKILRQACDMIPGGPTENLEAHRMAEGKDSAFAGFDYQYVAKKVAPTFKIPNGELYSRLESGKGEIGVFIQGNNDVTPWRFKIRAADSNNLQILPHILKGHKVADIMAILGSIDVIMGSVDR", "output": "NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration."}]}
+{"id": "function_test_1642", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRPSGRAPDQLRELSFTRNYTVHAEGSVLVAFGNTKVLCTASVEDGVPRFLKGKGQGWLTAEYSMLPRSTHTRSGREATRGKQGGRTLEIQRLIGRSLRAAVDMKALGERTIYLDCDVLQADGGTRTASISGACVALVDAFTYLLETKKIKNDPLTGLVGAVSVGMYKDTPVLDLDYAEDSNAGTDMNVVMTQQGGFIEIQGSAEGAPFTREQSDNLLELAENGIGEIIKAQQVALGW", "output": "Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation."}]}
+{"id": "function_test_1643", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MITAPIRTTARDTQIFDLISKEAHRQEEGIELIASENFTSKQVMEAMGSVLTNKYAEGLPGKRYYGGCQVVDQVEQIAIDRLKKLFGAEWANVQPHSGAQANAAIMIACLNPGDSILGFDLSHGGHLSHGSPVNMSGKYFKAHFYGVEKESGLINMDIVEATALKVKPKMIICGASAYSRDWDYARFRKIADSVGAILLADISHPAGLIAKGLLNDPIPHCHIVSTTTHKTLRGPRGGVIMMGKDFENPFGLKTPKGETRMMSNVLDMGVFPGTQGGPLEHVIAAKAVAFQEALSTDYLQYAKQIQKNAQIMAEAFLKKGYDIISGGTDNHLMLIDLRSKNLTGKEAENALIRADITINKNMVPFDDKSPFVTSGMRVGTAAITSRGMVGDDMIRIVEMIDTVLMNQTKDSVIETVRKDVNNWMAQYPLYI", "output": "Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism."}]}
+{"id": "function_test_1644", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNNKYAEYLPIAIQLMVTLGFISVTLLSSWLLGPKVKSKKKLDAFESGLDPVGNARVQFSIKYFLVATLFVLFDVEVIFFYPWAVNFNYFAEAVNKWEGFVKMLLFMTSLLIGFIYVIKKKALDWE", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_1645", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKQFEVNFDGLVGPTHNYAGLSYGNVASLNNASAQSSPKQAAKQGLKKMKALADLGMIQGVLAPQARPDVDALRRLGFSGSDANVLQQAAKQAPAIFQACCSASSMWTANAATVSPSADTADGKVHFTPANLTNKYHRSLEPQVTGNILKATFANQQYFSHHNHLPDNEHFGDEGAANHTRLCREYGERGVELFVYGRYAFDKSKPAPVKFPARQTFEASQAVARLHGLSDDNVVFIQQNPDLIDQGVFHNDVISVGNQNVLFYHEQAFLDTDKAFAEIKQKYGAGDLHFIKVITEQVSLQDAIKSYLFNTQLVTLANGEMAIIAPTDCEENPAVSAYLNELVSLNTPIKHIRYYDVKQSMRNGGGPACLRLRVAMNETELAAVNQSTMMNDAQFERLNNWVDKHYRDRLSVDDLRDVALLNESRTALDELTQLLKLGSVYPFQKV", "output": "Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2)."}]}
+{"id": "function_test_1646", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNLQVRLQDAALDGVGNHRHRMEHPRKLIPELCKQFYNLGWVTGTGGGISIKLDDEIYIAPSGVQKERILPDDLFIQNIDGDDLQLPPDYKKLTKSQCTPLFMLAYREKNAGAVIHTHSQSAVIATLVWPGREFRCTHLEMIKGIYDHELGRYLRFDEELIVPIIENTPFEKDLEQRMEHAMKEYPGSSAVLVRRHGIYVWGHTWQKAKAMAECYDYLFSLTVEMKKLGLDPNDIPKYYRSNK", "output": "Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P)."}]}
+{"id": "function_test_1647", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQHLVLIGFMGSGKSSLAQELGLALNLEVLDTDMIISERVGLSVRGIFEELGEDNFRMFEKNLIDELKMLKNPHVISTGGGIIMHDNFKGLGTTFYLKMDFETIIKRLSKKEREKRPLLNNLTQAKELFEKRQALYEKNASFIINAQGGLKKSLKQALQFIA", "output": "Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate."}]}
+{"id": "function_test_1648", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAKQEYKQLPKRAEIHSATEQFKDTIKTSLGLDLFKGLGLTIKEFFSPSVTIHYPMEQLPLSPRYRAVHNLQRLLDSGSERCIGCGLCEKICTSNCIRIITHKGEDNRKKIDSYTINLGRCIYCGLCAEVCPELAIVMGNRFENASTQRSQYGSKSEFLTSEQDAKDCSHAEFLGFGFVSPNYNERMQATPLDYVQEPSKEESKKETPTSPEANKGDENV", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_1649", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNVFYDKDADLSLIKGKQVTIIGYGSQGHAHALNLKDSGVNVTVGLRKGGASWSKAENAGLSVKEVAEAVKGADVVMMLLPDEQIADVYAKEVHANIKQGAALAFAHGFNVHYGQVIPRADLDVIMIAPKAPGHTVRGTYSQGGGVPHLIAVAQNKSGAARDIALSYAAANGGGRAGIIETNFREETETDLFGEQAVLCGGTVELIKAGFETLVEAGYAPEMAYFECLHELKLIVDLIYEGGIANMNYSISNNAEYGEYVTGPRVVTEETKKAMKQCLTDIQTGEYAKSFILENKAGAPTLQSRRRLTAEHQIEQVGAKLRAMMPWIAKNKLVDQTKN", "output": "Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate."}]}
+{"id": "function_test_1650", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSETFIYPQANLIAGVDEVGRGPLVGAVVTAAVILDPNRPIVGLADSKKLSEKRRLSLYDEITEKALSWSLGRAEPEEIDQLNILHATMLAMQRAVSGLHIVPDYVLIDGNRCPKLQMPSLAVVKGDSRVAEISAASILAKVTRDREMTELDLLFPEYGFAQHKGYPTAFHLEKLAALGATVHHRRSFGPVKRVLGLV", "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."}]}
+{"id": "function_test_1651", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MVVELKNIEKIYENGFHALKGVNLELKKGDILGVIGYSGAGKSTLIRLINCLERPSSGEVLVNGVNLLNLKPKELQKARQKIGMIFQHFNLLSAKNVFENVAFALEIARWEKNKIKSRVHELLELVGLEDKMHFYPKQLSGGQKQRVAIARSLANCPDLLLCDEATSALDSKTTHSILTLLSGIQKKLDLSIVFITHEIEVVKELCNQMCVISSGEIVERGLVEEIFANPKHAVTKELLGIKNEHGDQKCQDVYRIVFLGEHLDEPIISNLIRRFKIDVSIISGNIEELTTKDIGYLVVRFLGSTTETQRALEYLNALGLQVEKLKD", "output": "Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system."}]}
+{"id": "function_test_1652", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTASSGGYQGWERRNNNIPETVGILFLQVRAVSSGKKAAQCRETAPTAGLSESSRPRLFAMDYSKGSKKRKAITKDVDEDPSVVSGDEYDLEALDRNDSDSSADASDSEIELIGDFSSDDGEDDDGEDDDELDSDEVPSDTEPFARVKSGNIATGLDGSLDGESNDLSDDNEPNYRIEKDANGNDRYIYPEINPDDNSEYSEVDEEANTIGDIPLSFYDQYPHIGYNINGKKILRPAKGQALDALLDSIEIPKGWTGLTDPSTGKPLQLSQEELELLRKVQMNEITQDGYDPYQPTIEYFTSKQEIMPLSAAPEPKRRFIPSKHEAKRVMKIVKAIREGRILPYKPPEEEDATQEGIQTYDLWADESPRPDHPMNIPAPKLPPPGYEESYHPPPEYLPDKKEKEEWENQDEEDREREYLPTDYSTLRKVPGYERFVKEKFERCLDLYLAPRVRRSKLNIDPESLLPKLPSPEELKPFPTTCATLFRGHRGRVRSLAIDPTGVWLASGGDDGTVRVWELLTGRQLWSVKLSDEDAVNVVRWRPGKEAVVLAASVGDSIYLAVPDVVNLELEAASLEVIDAGWGYATSTGTSTTKKTSPVQWTRPASSLADSGVYAVIPLGYIAKSISWHRRGDYFVTVCPGTSTPASVAIAIHTLSKHLTQYPFRRRLKGGGSPQVAHFHPSKPILFVANQRSIRAYDLSRQTLVKILRPGARWISSFDIHPTSSSTSGGDNLIVGSYDRRLLWHDVDLSDRPYKTLRYHQKAIRAVKYHPHYPLFADTSDDGSLQIFHGSVTGDLLSNANIVPLKVLKGHKVTGDLGVLDLDWHPREAWCVSAGADGTCRLWM", "output": "Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome."}]}
+{"id": "function_test_1653", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSGVLGIRDLGLQPYEPVLEAMRRFTEQRGPESQDEVWLVEHPPVFTQGQAGKAEHLLIPGEIPVVQTDRGGQVTYHGPGQLVAYLLLDVRRLSIGVRELVSRIEQTLIDLLASYGVQAVAKPDAPGVYVDGAKIASLGLRIRNGRSFHGLALNVDMDLAPFRRINPCGYAGLAMTQLRDLAGPIELDEVRTRLRGQLVRHLDYAEQTTLTGGID", "output": "Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate."}]}
+{"id": "function_test_1654", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLKLKKLQLLGFKSFCDRTELKFPGDGIAAIVGPNGCGKSNIADAISWVLGEQSAKSLRGIHMQDVIFAGTRDRKPTGMAEVSLTLIDPEQYEGKIVEPEIEIRDEMPDDWDEAAAREASMEEVDEYTAEVQPGTNTEAEATEQQAAPSEGAAPTTEATAPSTENEAAPSEVAEGQPSDAQAAVINPNAVVLKIRRRKFNTNRFKKGEICVTRRLFRSGDSEYLLNGKLSRLRDVHDIFMGTGLGPESYAIIEQGRIGQILSSKPTDRRAIIEEAAGITKYKTKKRLAEARLEDAKSNLARVNDIFDEVTRQMNSLKRQAAKAERYAKLRDEMREKLRVVLASKFALIDAEIAGLEAELTTVTEEIATRTDAVQQMDNEHGERVQRGYAIDAEAKQNRESLNNVSREMDRAAQRRRTNEERCAELVARSAGAEAEIQNTTEQLGRLEEELATNRQVLESAAADVAVAQSDLQTKQQEASAAAANLMNVEREQEQRRSQIFQAVNAASNVRNRITQAEERIANLDREHGRVTGELSSATLQLESFGGQRGQLGLEFESANTRVNALSSEITDARGSLQQKRQEEIEAKRHVDTLRAEYATLLGKKGSLESVINEHGYSTESVKRLFQSGGLREGNTPAGVLADFLEVEDKYEHVVEDFLRDELNYVVVKSWGAADEGLRLLKGDVDGRATFLVHPSDSQAKFSFVLDESMRLPFTPDRVTPMKNCIRVLNGFGKSLEVVLPKLGNGYIVPDPAIGRELALENPDAFFLSQSGECFHNVTVTGGKQRSQGPLSLKRELRDVMRCIDDVERSLRDGEARVLMLGKEIAELTSLLQRLEDEKREGEKQAMTSGHTLRQLENEMARVRDRHATYERELQRVSNEKSERENAIGGLRMELEAAEARHQELEAAMNAATQSLDELRTARDNASHAASEARAQAAALEERHRAAASSLQRIESMVQEVSARIGKLKGQVESAAAEKQQRESENETIAEQLVTWTAEREAAEARDRELQTESEQVRARIAEIEEELKTARQALDAARDRRGELHASVARLQSDGEHMAETCVQELSVTRPDLMAIEELPRLTGDELAVADTEQKDMRTKLENMGPVNMMALEEYKETAQRHEFLETQRKDLLDSIENTQNTIKEIDQITKVKFDEAFAAINENFGKAFKKLFGGGQGFMKLTDELNSSDSGIDVIASPPGKKLQNVLLLSGGEKTLTAFSLLVGIFQYAPSPFCILDEVDAPLDETNVARFNELVKEMSMQTQFILITHSKRTMATAPVMYGVTMQEPGVSKIVSVRFGEEAARATA", "output": "Required for chromosome condensation and partitioning."}]}
+{"id": "function_test_1655", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MVADVLLTHFNQLFCLNDPGHPLTGQEMKKATIVEDGYIAIKDSLIVALGSGEPDAELVGPQTIMRSYKGKIATPGIIDCHTHLVYGGSREHEFAKKLAGVSYLDILAQGGGILSTVRATRSASFDNLYQKSKRLLDYMLLHGVTTVEAKSGYGLDWETEKRQLDVVAALEKDHPIDLVSTFMAAHAIPEEYKGNPKAYLDVIIKDMLPVVKEENLAEFCDIFCEKNVFTADESRYLLSKAKEMGFKLRIHADEIASIGGVDVAAELSAVSAEHLMMITDDGIAKLIGAGVIGNLLPATTFSLMEDTYAPARKMIDAGMAITLSTDSNPGSCPTANMQFVMQLGCFMLRLTPIEVLNAVTINAAYSVNRQERVGSLTVGKEADIAIFDAPNIDYPFYFFATNLIHQVYKKGQLTVDRGRIL", "output": "Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway."}]}
+{"id": "function_test_1656", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKRIAIDAMGGDNAPKAIVEGVNQAIEAFSDIEIQLYGDQTKINSYLIQSDRVAIIHTDEKIMSDDEPAKAVRRKKKASMVLAAKAVKEGKADAIISAGNTGALLAVGLFVVGRIKGVDRPGLLSTIPTVTGLGFDMLDLGANAENTAKHLHQYAILGSFYAKNVRGIANPRVGLLNNGTEETKGDPLRKATYELLTADNTISFVGNVEARELMSGVADVIVSDGFTGNAVLKSIEGTAISIMGQLKQIINSGGIKTKIGASLLKSSLYEMKKTLDYSSAGGAVLFGLKAPVVKSHGSSDVKAIFSTIKQVRTMLDTNVVGQLVEEFAKETQVND", "output": "Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA."}]}
+{"id": "function_test_1657", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVLLLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDIIFGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKYCTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGSFADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNLMGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTDDFEKTMKLIADVNFDMSYSFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGTSRKSIMELSGRTENNRVVNFEGTPDMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRVAETPESVIARTRKENDLGVGYYQP", "output": "Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine."}]}
+{"id": "function_test_1658", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRILGLTGSIGMGKSTTARLFAEAGVPVYDADATVHQIYEGEAAPAVETAFPGTTVNGKVDRALLSARVLHDAAAMQRLEAIVHPMLRAHHQQFLADAEKSGAPVAVVDVPLLYETGGDARVDAVVVVTTSHQVQRARILARQGMTDEKLDALLARQLPDAEKRQRADFVVDTSNGLEPVRAQIREILAATAKMPQRRA", "output": "Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A."}]}
+{"id": "function_test_1659", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKIHEYQGKEILRQAGVPVPRGIPAFTVQEAVEAAQKLGGPVWVVKAQIHAGGRGKGGGVKLARSIDEVKKLAGEILGMQLVTHQTGPEGQKVRRLLIEDGADIQKEYYVSAVTDRASQRVAMIVSSEGGMSIEDVAHDTPEKIITEIVDPATGLTVAQATKLANAIGVPAGSTAQAVDVLQKVYKVYMDTDASLVEINPMILEGNGNIKAIDAKFNFDDNALFRHPEIVAYRDLDEEDPAEVEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGASPANFLDVGGGATPEKVTEAFKIMLKNPNVKVILVNIFGGIMKCDTIAAGVIAACKAVNLNVPLVVRMKGTNEELGKKLLAESGLPIISADTMADAAQKAVAAVKAA", "output": "Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit."}]}
+{"id": "function_test_1660", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTSDKNPYKTEQRMGAVKAVSGPVVIAENMGGSAMYELVQVGSFRLVGEIIRLEGDTATIQVYEETGGLTVGDPVYCTGKPLSLELGPGIMSEIFDGIQRPLDTIYRMVENVFIPRGVQVKSLNDQKQWDFKPCLKVGDLVSGGDIIGSVVENSLMYNHSIMIPPNVRGRVTSIVPSGNYTLQDDIIELEYNGTVKSLKLMHRWPVRTPRPVASKESGNHPLLTGQRVLDALFPSVQGGTCAIPGAFGCGKTVISQALSKFSNSDAVIYVGCGERGNEMAEVLMDFPTLTTVIDGREESIMKRTCLVANTSNMPVAAREASIYTGITLAEYYRDMGKHIAMMADSTSRWAEALREISGRLAEMPADGGYPAYLSARLASFYERAGRVTCIGGPKREGSVTIVGAVSPPGGDFSDPVTSATLGIVQVFWGLEKRLAQRKHFPSVNWLISYSKYLNALEPFFNTLDPDYMRLRSVAAEILQREEELQEIVQLVGKDSLSESDKIILETAKVIREEFLQQNAFTPYDKYCPPYKTCWMLRNIVAFYEESQRVVAESAGELKITWNYIREMIPHIYTGLTEMKFRDPQEGEEANVEFYRKQNEEIVSAFASLLQ", "output": "Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells."}]}
+{"id": "function_test_1661", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRQKTLDVLEFEKIKSLVANETISDLGLEKVNQMMPATNFETVVFQMEETDEIAQIYNKHRLPSLSGLSKVSAFIHRADIGGVLNVSELNLIKRLIQVQNQFKTFYNQLVEEDEGVKYPILDDKMNQLPVLTDLFQQINETCDTYDLYDNASYELQGIRSKISSTNQRIRQNLDRIVKSQANQKKLSDAIVTVRNERNVIPVKAEYRQDFNGIVHDQSASGQTLYIEPSSVVEMNNQISRLRHDEAIEKERILTQLTGYVAADKDALLVAEQVMGQLDFLIAKARYSRSIKGTKPIFKEDRTVYLPKAYHPLLNRETVVANTIEFMEDIETVIITGPNTGGKTVTLKTLGLIIVMAQSGLLIPTLDGSQLSVFKNVYCDIGDEQSIEQSLSTFSSHMTNIVEILKHADKHSLVLFDELGAGTDPSEGAALAMSILDHVRKIGSLVMATTHYPELKAYSYNREGVMNASVEFDVDTLSPTYKLLMGVPGRSNAFDISKKLGLSLNIINKAKTMIGTDEKEINEMIESLERNYKRVETQRLELDRLVKEAEQVHDDLSKQYQQFQNYEKSLIEEAKEKANQKIKAATKEADDIIKDLRQLREQKGADVKEHELIDKKKRLDDHYEAKSIKQNVQKQKYDKIVAGDEVKVLSYGQKGEVLEIVNDEEAIVQMGIIKMKLPIEDLEKKQKEKVKPTKMVTRQNRQTIKTELDLRGYRYEDALIELDQYLDQAVLSNYEQVYIIHGKGTGALQKGVQQHLKKHKSVSDFRGGMPSEGGFGVTVATLK", "output": "Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity."}]}
+{"id": "function_test_1662", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSHDTNTIDSRTHEGELNKLGFWIFITAEFALFGTLFATLLTLQHGGDYAGKMTTELFELPLVLIMTFALLFSSYTCGIAIYYMRQEKQKLMMFWMIITLLLGLVFVGFEIYEFAHYASEGVNPTIGSYWSSFFILLGTHGCHVSLGIVWAICLLIQIQRRGLDKYNAPKLFIVSLYWHFLDVVWVFIFTAVYMIGMVYSG", "output": "Catalyzes quinol oxidation with the concomitant reduction of oxygen to water."}]}
+{"id": "function_test_1663", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MINQVYQLVAPRQFDVTYNNVDIYGNHVIVRPLYLSICAADQRYYTGRRDENVLRKKLPMSLVHEAVGEVVFDSKGVFEKGTKVVMVPNTPTEQHHIIAENYLASSYFRSSGYDGFMQDYVVMAHDRIVPLPNDIDLSTISYTELVSVSYHAIQRFERKSIPLKTSFGIWGDGNLGYITAILLRKLYPEAKTYVFGKTDYKLSHFSFVDDIFTVNQIPDDLKIDHAFECVGGKGSQVALQQIVEHISPEGSIALLGVSELPVEVNTRLVLEKGLTLIGSSRSGSKDFEQVVDLYRKYPDIVEKLALLKGHEINVCTMQDIVQAFEMDLSTSWGKTVLKWTI", "output": "Catalyzes the NADPH dependent reduction of D-ribulose 5-phosphate to D-ribitol 5-phosphate."}]}
+{"id": "function_test_1664", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIESISKIIKYNFKNPQLLNEALTHPSLVSKDTLKFNYERLEFLGDAVLNIVISEMLFNIFPKDTEGNLAKKKTALVCGNKLVEVAQSINLGQFIMMSDGERACGGINNFRNLENALEALIGAIYLDGGFTAAQDFIYLFWEHSATHMNVPPQDAKTILQELVQGKRLPAPAYHTIDKSGPDHNPTFTVEVRIPSYQAIQATGHNKKLAEQKAASLMLNQIHNKTK", "output": "Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism."}]}
+{"id": "function_test_1665", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MREFMHYVTNAFYGATGWNDDNTYKELNVTARELIDFPLPRGLRLTLSSLATPHFATSYQLGSVGIVDGSISYLHSSVPLTGIAARSDRIPLPALLRSYRRLHDLGSKDQQQYVGAEHAPTESTPPAVAKVDGSSLLYGRLYLPQSLLEGMVVRRFTPALQVQLSAVSERSLRNGGTLLGLVQYDKRKYGVEGLASTDGGLLGVRGLYNFGGDASSSAMNPPSGTSASETNGSGPSVEKERIYGRFSAGAELYYGTLNKSGGMSLGARFATLPAHRGTPLTATLTINPLMGNINATYAVLAREYCSLATKMEFNVYSYESEWAVGVELWSNRRPAGFLLGANPNDQAEPAPEPPRKSNERSFQAKMEWRLDDPEPEPQSPVAGEKSADDGPKEEYKGVLKARFDQNFRFGLLWEGRVKSLIFSLGTGRSD", "output": "Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria."}]}
+{"id": "function_test_1666", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MISSVAPPPEKMLFQLSLRRRGISDRGVLQAMESVPRDRFVDAVHRDSAWRDTALPIACGQTISQPFVVAYMTEQLHLQPGHRVLEIGTGSGYHAAVLSRLVRDVVSVERFKTLADRARARLKELNYANVEVVLGDGFALPEGQGTFDRILVTAAMAELPQPLLDLLDPDGILIAPIGPGNGRQTLIRVQRKDDGFLRKPLVDVRFVPALPGIAREL", "output": "Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins."}]}
+{"id": "function_test_1667", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPYTLEDLKAHGLSPAEYQQIQQQLGRDPNPNELAMFGVMWSEHCCYKNSRPLLKNFPTTGERVVVGPGENAGVVDLGEGDWLAFKIESHNHPSAVEPFQGAATGVGGILRDIFTLGARPIALLNSLRFGPLTDPRNRRLMARVVEGIAHYGNCVGVPTVGGEVAVDPCYSGNPLVNVMALGLLETPAVVKSAARGVGNPVLYVGATTGRDGIRGASFASAELKEDAQQDRPAVQVGDPFLGKCLIEACLEAFATGAVVAAQDMGAAGITCSTAEMAAKGGVGIRFDLDRVPARESGMAAWEYLLSESQERMLLVVQKGREAEVMEIFHRWGLQASVAGEVIAEPLVEIWHQGSCVVQVPVRALAEDTPVYVRPVLPEPPAYVQAAWQWDPATLPPCDCQGIHLAQATLAWKEVLLQLLASPTLASKAWIYRQYDHQVQNNTVLWPGQGDAAVIRIRSQRFGVGEVPPLRASRKAIAATLDGNGRWVYLDPYEGAKAAVAEAARNLTCVGADPLAVTDNLNFGNPENPVVYWQLALACRGIGDACRALGTPVTGGNVSLYNETLTPQGSQAIYPTPVIGMVGLIPDLKCICGQGWQQEGDLIYLLGSQALTSLGGSEYLAVIHQQVTGRPAPVDLELEKRVQAACRHGIRQGWVRSAHDCSEGGLAVALAEACLSGGRGATLSLAPGSLRWDQALFGEGSSRILVSVDPAQRSAWEAYLEAQLAGQWQLLGEVGSPADPLLLRTAEEDPLLVVSLAAMQAAYHGAFSD", "output": "Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL."}]}
+{"id": "function_test_1668", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSQRKYFGTDGVRGEVGGPVINAAFALRLGYAAGRVLVRRNASRQGGRPQVLIGKDTRISGYMLESALEAGLSAAGIDVVLAGPIPTPGVAYLTRALRLVAGIVISASHNPYQDNGIKFFSAEGTKLPDEVEAEIEAALEQELGCVKSEDLGRARRMSDSQGRYIEFCKSTVPHSLDLHGMKLVVDAANGAAYHIAPHVFRELGAEVYAIGVSPDGFNINKGVGALHPESLAEEVKARGAHYGIALDGDADRLQMVDASGRIYNGDELLYAIVRDRMRQGKVEGVVGTLMTNYGFELAMGRLGVAFERANVGDRYVLEQLLARGWQFGGESSGHLLCLDCHTTGDGTIAALQVLAALHANKASLSDWIADLRLYPQVMINVPLQPGQDWKTHAGLAAARAGVEAELAGRGRVLIRASGTEPKLRLMVEAEDFALAQASAQKLADSLG", "output": "Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate."}]}
+{"id": "function_test_1669", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRPAQASIDLEALRHNYRLAKRLGGSKALAVVKADAYGHGAVPCAQALEPEADGFAVACIEEALELRQAGIRAPILLLEGFFEHDELRLIAEHDLWTVAATPQQVRALAAFQSPRPLRVWLKMDSGMHRLGLSPEDFRAAWLRLRGLPQIASLVLMTHLARADELDCSRTDEQAVAFALTAGGMRAETSLRNSPGLLGWPALRNDWSRPGLMLYGANPFPQDTENTAQLRPVMTLRSRIILVRDLPVGEPVGYGARFVAERPTRVGVVAMGYADGYPQFAPNGTPVLVDGQVCPLIGRVSMDMLTVDLTDHPQADIGATVQLWGQAPRVGPLATQCNVSAYQLLCGLKRVPRTYVASAAVGEVAAR", "output": "Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids."}]}
+{"id": "function_test_1670", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPDLSLERACGGRVAGVDEVGRGPLAGPVVAAAVVIDAGRADPALLARLDDSKKLSAALRQRLATALLADPGVEVGLGEASVAEIDRINILQATFLAMGRALAKLAPPVDLALVDGNRLPPLPCPGQAVVRGDGLSLSIAAASIVAKVHRDAAMATLAQALPGYGWERNAGYGTAEHLAALDRLGATPHHRASFAPVREALARSALPGHKCVTALTFS", "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."}]}
+{"id": "function_test_1671", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLLALAQWLQGDASFLRLFTYLTFRAVMATITALVIGLVCGPWVIRKLTQMKVGQAVRKDGPQTHLVKSGTPTMGGVLILIGIAVATLLWGDLTNRFIWIVMLVTFGFGVIGWVDDYRKVVYKDPRGMSSREKYFWQSVIGLFAAVYLAFSVSEANNVRVFDLFMAWVRSGLSMGLPARADLMLPFLKSISYPLGVWGFIALTYFVIVGASNAVNLTDGLDGLVIMPVVLVGASLGVFAYVMGSAVYSKYLLFPHIPGAGELLIFCSAMGGAGLAFLWYNTHPAQVFMGDVGALALGGALGTVAVIVRQEIVLFIMGGIFVAETLSVMLQVTWFKYTKKRYGEGRRIFKMAPLHHHFELSGWKETQVVVRFWIITLMLCLFGLSTLKLR", "output": "Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I."}]}
+{"id": "function_test_1672", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSKLANRADWADDEEFDDPSALPAQQVTTNKDGTKTVVSYRFNDEGKKVKVTRRIKTTVVREHVNPQVAERRSWAKFGLEKGHAPGPSFDTTSVGENIAFRPSINWKAQAAEAEKNGGEKGSMKDQLKDKKVKCRICSGEHFTARCPFKDTMAPVDEPTAGGAGEDDEAAAGAVGTGSGSYVPPHLRKGAAGGGERMGGKFEKDDLATLRVTNVSELAEEGELRDLFERFGRVTRVFLARDRETQRAKGFAFISFADRSDAARACEKMDGFGYRHLILRVEFAKRTT", "output": "RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA."}]}
+{"id": "function_test_1673", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSYNGGYQRDQRDSYRNGGGGGYSNGYSNGNSNGYSGGGSGGGYGGGYGGGGYGGGYGGRGGGAGGGDRMSNLGAGLKKQEWDLDSLPKFEKSFYKEHPDVANRSQRDVDEFRKKFEMSVQGKNIPRPVETFDEAGFPQYVLSEVKAQGFERPTAIQSQGWPMALSGRDVVGIAETGSGKTLSYCLPAIVHINAQPLLAPGDGPIVLVLAPTRELAVQIQAEITKFGKSSRIRNTCVYGGVPKGPQIRDLSRGVEVCIATPGRLIDMLEAGRTNLRRVTYLVLDEADRMLDMGFEPQIRKIISQIRPDRQTCMWSATWPKEVRQLASDFLNDYIQVNIGSMDLSANHRITQIVEVVSDFEKRDKMIKHLEKIMENRGNKCLIFTGTKRIADEITRFLRQDGWPALSIHGDKQQQERDWVLNEFKTGKSPIMVATDVASRGIDVRDITHVLNYDYPNNSEDYVHRIGRTGRAGAKGTAITFFTTDNSKQARDLVTILTEAKQQIDPRLAEMVRYSGGGGGGRGGYGRWGGRGGGRGRGGNYTASNAAPLGGNRRW", "output": "ATP-dependent RNA helicase involved nonsense-mediated mRNA decay and ribosome biogenesis through rRNA processing."}]}
+{"id": "function_test_1674", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKTVTVKDLVIGTGAPKIIVSLMAKDIARVKSEALAYREADFDILEWRVDHFADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNRAAIDSGLVDMIDLELFTGDDQVKETVACAHAHDVKVVMSNHDFHKTPEAEEIIARLRKMQSFDADIPKIALMPQSTSDVLTLLAATLEMQEQYADRPIITMSMAKTGVISRLAGEVFGSAATFGAVKKASAPGQISVNDLRTVLTILHQA", "output": "Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate."}]}
+{"id": "function_test_1675", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKTMFTLEERVELAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVYQALMAKLA", "output": "Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate."}]}
+{"id": "function_test_1676", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTNIRKSHPLLKIVNNAFIDLPAPSNISSWWNFGSLLGICLIMQIMTGLFLAMHYTSDTATAFSSVAHICRDVNYGWIIRYLHANGASMFFICLYIHVGRGLYYGSYAFLETWNIGIILLFTVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYVGTTLVEWIWGGFSVDKATLTRFFAFHFILPFVIAALAGVHLLFLHETGSNNPTGISSDMDKIPFHPYYTIKDILGVLLLILTLLLLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILALIPLLHTSKQRSMMFRPISQCLFWTLVADLLTLTWIGGQPVEPPFIMIGQVASILYFSLILILMPVAGIIENHILKW", "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."}]}
+{"id": "function_test_1677", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNPYVLTILLSSLGLGTILTFASSHWLLAWMGLEINTLAIIPIMAQQSHPRAIEATTKYFLTQATAAAMILFASTTNAWLVGEWEIHQLSHPLATTTVMLALALKLGLAPVHFWLPEVLQGLELTTGLILSTWQKLAPFALMIQVAPTINSSLLIAMGLLSTLVGGWGGLNQTQLRKILAYSSIAHLGWMVLILQYAPSLTLLSLFLYIIMTSSAFLTLKTNNSLTINTLATSWTKSPTLAALTALVLLSLGGLPPLSGFMPKWLILQELTKQGLPLSATLAAMTALLSLYFYLRLCYAMTLTIYPNTLTATAPWRLNFTLITLPLSIITILALGLLPLTPAVTTLLTL", "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)."}]}
+{"id": "function_test_1678", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLEAKSAALLEDTIDYVFDNQALLLEALTHKSFSNEQNDRTEPDNERLEFLGDAVLGVVVSHYIFRTFPHLPEGELTRIRSEVVSEKGLTVIGKAICLGDYMRLGKGEERSGGRQKSSLLANTMEALLGAVFCDGGFDSVRRVIEALFIPHIQRAARRKTGVDYKTRLQERLQARFGDVPQYVLIHADGPPHQRSYSVEAHFRGSCIGQGQGRSKKSAEQAAAKQALEYLEE", "output": "Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism."}]}
+{"id": "function_test_1679", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MALLGVNVDHVATIRQARGTNEPDPVTAAALAELAGADGITIHLREDRRHIQDRDVELIRQTVKTRLNLEMAATDEMVGIALKVRPDAVTLVPEKRKELTTEGGLNVALLRQTLKKHIDLLKQGGISVSLFIDPDLEQVKASHRIGADAIEIHTGAYCDAACAATRSKELDKLTNAVKAGNKLGLLVHAGHGLTYFNIQPVAAIGGIREFNIGHSIISRAVLVGMDRAVREMKDLVGGA", "output": "Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate."}]}
+{"id": "function_test_1680", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNELLLNLVDPLHQWFLGLGDGGVVLWSVLKILLIAVPVIVAVAFYVVWERKLIGWMHVRHGPMYVGMGIFQAFADVFKLLFKEIVQPTSSHKAMFVIAPLLTLAPAFAAWSVVPFDAKLVLSNANVGLLYLLAMTSLGVYGIILAGWASNSKYAFLGAMRSAAQVVSYEIAMGFALVGVMIASGSVNLSQIVFAQAGNSGFFDWFLIPLFPLFIVYWVSGVAETNRAPFDVVEGESEIVAGHMVEYSGGAFALFFLAEYANMILVSFLISIFFLGGWLSPIQGWVNADVSPWIDWLWKGGWPWLLMKVFFFASAYIWFRASFPRYRYDQIMRLGWKVFIPLTIVWIAVTALMVFYGVIQKGV", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone."}]}
+{"id": "function_test_1681", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAPASEAGPAQDPLFSGLILPRSRILDAEALTRSILAEIDAAGPLDPKSARAIAVRQMTEAKAAGNRALSETFEARPREARGLIRAQAALTDGLVTAALRVACERLHPLANPTEAERIAVLAVGGYGRAEMAPHSDVDLLFLTPWKITPWAEMVIESMLYMLWDLRLKVGHSSRTVKDCLRLGREDITIRTALLEHRFLAGHAPLAAELDETLWNDLFRGTGAEFIDAKLEERGQRHKRQGGQRYVLEPNVKEGKGGLRDLQTLYWIGKYLNRVPSPSGLVAAGLLTRDEFETFERAESFLWAVRCHLHYATGRATDQLTFDLQVEVAARMGYADTRGRRGVEVFMQDYFRHATRVGELTRVFLAQLEARHEKREPKIMGLFRRKKRLKPEYSLVNGRIDVLDPKAFLADKLNLLRIFEEALRTGFLIHPGAMRLIAANLHLIDEEMQHDREANRIFLDMLLRHGNPERALRRMNELGVLGAFIPEFERIVAMMQFNVYHHYTVDEHTIQCISTLAQIERHELDEELPIANRILTDGISRRVIYVALLLHDIGKGRPEDHSILGAQIARRVAPRFGLTAEECETVEWLVRYHLLMSDMAQKRDIGDPRTVRDFAKAVRSKKRLDLLTVLTVCDIRGVGPGTWNNWKAQLLRKLYRDTVTALDAGLESLNRENRADEAKRALRELLEEWDPKDLRAELARHYPPYWQALSNATHAVFARMLRGLGETEIRIDLDPDPDRDATRACFALADHPGIFSRLAGALALVGANVVDARTYTTKDGYATAVFWIQDSEGSPYEISRLPRLTSMIDKTLKGEVVAREALKDRDKLKKREAQFRFPTHIAFDNEGSDIYTIIEVDTRDRPGLLYDLTRTLAANNIYIASAVIATYGAQVVDSFYVKDMFGLKLHQKNRQETLEKKLRQAIVEGAERAKQ", "output": "Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen fixation and metabolism."}]}
+{"id": "function_test_1682", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNFDIPEFLPALPEIAVLGMGCVLLLAVAYGGGQSGKIAYWITQLTLVIAALLTFYFLDYSSQSVTFNGSYIKDSLSDTLKLFIYIIVFAVFLYSRDYLQARALDKGEFYVLGLFGVLGMMVIASAHHFLTLYLGLELLSLSQYAMVALLRNNRWASEAAMKYFVLGALASGMLLYGMSMIYGATGDLHVAAVAEGIGGSGSSQVLVFGVVFIVVGLAFKFGAVPFHMWLPDVYHGAPTAVTLYIGTAPKIAAFALLMRLLVEALGDVQAHWQDMLIILSVLSMAIGNVVAIAQTNLKRMLAYSTIAHVGFLLLGILTGTGVGYAAAMFYVIVYALMSLGSFGMIIFLSRSNFEADRLEDFKGLNERSPWFAFMMLILMFSLAGVPPTVGFYAKWAVIMAIIDKELLWLAVVAVLFSVIGAFYYLRVIKFMYFDSPTEEISLSKRADFRWCMSANGLAMLGLGIFPGALMGLCVAVLG", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_1683", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKSHREMLRGIQREAGITQRWIGKESLDRRVMEAMKAVPRHEFVPDEQRPYAYDDAPLAIGCGQTISQPYIVALMTDLLDSTPDDIILEVGTGSGYQAAVLSRLVKKVYTIETIEELAQQAEARLERLGYSNVEVQTADGYFGWPEQAPFDGIMVTAAAPSIPKPLIDQLKPEARLVLPLGAGSPQELMVVTKKENDEIDIHRVLGVSFVPLTGKHEVP", "output": "Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins."}]}
+{"id": "function_test_1684", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSVMPDHWIKDKAIQEKMIDPFIDYKESSGILSYGLSSYGYDARIDNKFKIFTNINPVTVDPKNFPLGSFIDKEEDICIIPPNSFVLAKTVEYFKIPKDILVMCVGKSTYARCGIVVNVTPLEPGWEGYVTLEFSNTTPLPAKIYAFEGACQFIFLKGDSQCSLSYNEMKGKYMKQLDVTLPIVNNS", "output": "Catalyzes the deamination of dCTP to dUTP."}]}
+{"id": "function_test_1685", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTISTSIVLNALNALGVSAEASGRNDLVVKTVEGDRKVSGSAYRETKDRGFHHGTLLLNADLSRLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEAITKAFFAHYGERVEAEIISPDKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFSWGGVELHFDVEKGHITRAQVFTDSLNPAPLEALAGRLQGCLYRADMLQQECEALLVDFPDQEKELRELSTWIAGAVR", "output": "Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes."}]}
+{"id": "function_test_1686", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRDELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGSFVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRKP", "output": "Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit."}]}
+{"id": "function_test_1687", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMSEEETRFFGLKRECGLHEG", "output": "Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor."}]}
+{"id": "function_test_1688", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG", "output": "Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)."}]}
+{"id": "function_test_1689", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGHLVSAVETAKLLLSRCHSLSITVLIFNNSVVTSKVHNYVDSQIASSSNRLRFIYLPRDETGISSFSSLIEKQKPHVKESVMKITEFGSSVESPRLVGFIVDMFCTAMIDVANEFGVPSYIFYTSGAAFLNFMLHVQKIHDEENFNPTEFNASDGELQVPGLVNSFPSKAMPTAILSKQWFPPLLENTRRYGEAKGVIINTFFELESHAIESFKDPPIYPVGPILDVRSNGRNTNQEIMQWLDDQPPSSVVFLCFGSNGSFSKDQVKEIACALEDSGHRFLWSLADHRAPGFLESPSDYEDLQEVLPEGFLERTSGIEKVIGWAPQVAVLAHPATGGLVSHSGWNSILESIWFGVPVATWPMYAEQQFNAFQMVIELGLAVEIKMDYRNDSGEIVKCDQIERGIRCLMKHDSDRRKKVKEMSEKSRGALMEGGSSYCWLDNLIKDMIK", "output": "In the presence of other necessary color factors, this glycosylation reaction allows the accumulation of anthocyanin pigments."}]}
+{"id": "function_test_1690", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRKPVIAGNWKMNMTCTEAIEYMRVLIPLLKDIPKKDREIVIAPPFTALYPLSEFIRDRNEYLSLSSQNVHWEDSGAYTAEVSPLMLNELSVKCAIVGHSEPRKYFSESDEQINKRAKSAQDHQLIPIVCVGETFQQREMGEAERVIRRQIEQGLEGIEVKRLIVAYEPIWAIGTGKTCEANEANRICGLIRKWIGYEDVIIQYGGSVKSNNIDEIMSMSDIDGVLVGGASLDPTNFARIANYEKI", "output": "Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)."}]}
+{"id": "function_test_1691", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPVATRQRSARAAGTAFSPLRWIGFLLGCIVAGVVAMQVYFFLQIAAWQYVAPSSTSFMRAERWRLCGFNVWNCSIDRRWVPYDQISRNLKRAVIASEDADFVNHPGYEIDAMLDAWERNKKRGRVVRGGSTITQQLAKNLFLSSEQHYLRKGQELAITWMLEFWLDKQRIFEIYLNSVEWGEGVFGAEAAAQHYFRTNAGKLGVGQAARLAAALPAPKCFDKKEYCANVRVNFRVKAGIIARRMGAATLPD", "output": "Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors."}]}
+{"id": "function_test_1692", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSDLYCVFGNPIAHSKSPAIHAAFAVQTAQDLRYEARLAALDGFGLAIAEFVAVGGKGANVTVPFKEEAYRLATRLSDRAARAGAVNTLVFDGPEVFGDNTDGAGLVRDITNNLGFSLVGKRILLLGAGGASRGVIAPLLAEKPASLIIANRSADKAVALAQAFADMAPLGGGSFAETAGKSFDLVINATSASLSGASLPLPPGIFAPGSLAYDMMYGKGETPFLTLARQQGAARCADGLGMLVEQAAEAFFVWRGIRPGTAQVLAELRAKLVA", "output": "Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)."}]}
+{"id": "function_test_1693", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSKTLYDKLWENHVVHQEADGTALLYIDRHLIHEVTSPQAFEGLKLAGRKPWRVSSIVATPDHNTPTDHWEEGIKDPISRQQVETLDANIREVGALAYFPFKDQRMGILHVVGPENGATLPGMTVVCGDSHTSTHGAFACMAHGIGTSEVEHVLATQCLLQKRSKTMLVAVEGKLGKGVTAKDVALAIIGTIGTAGGTGYAIEFGGSAIRGLSMEGRMTLCNMAIEGGARLGFVAVDDTTINYLKGRPFSPTGETWDRAVAYWRTLHSDAGAQFDRVVTLRAEDIRPQVTWGTSPEMVVSVDAVVPDPAKEADPVKREGMERALQYMGLNPNTPINQIAIDKVFIGSCTNSRIEDLREAASVLKGRHVAANVKLALAVPGSGLVKRQAEAEGLDKVFVAAGFEWREPGCSMCLAMNADRLEPGERCASTSNRNFEGRQGPGGRTHLVSPAMAAAAAIAGRFADVRDVL", "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."}]}
+{"id": "function_test_1694", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTNSSSQLAQLKQMTTVVADTGDIEAIAKFQPQDATTNPSLLLKAASLPNYQGLVKDSVAWAKTQSDNAEQQVIDAADKISVLIGLEILKIVPGRISTEVDARLSFDTSASITKAHKLIAMYNEAGISNDRILIKLASTWEGIKAAEQLEQEGINCNLTLLFSFAQARACAEAGAYLISPFVGRILDWYKKDTGRNDYASNEDPGVVSVTSIFNYYKLQGFNTVVMGASFRNIGEILELAGCDRLTISPQLMEELANSTDTVIQKLTACEATAEKEAALSQAEFRWQMNEDPMATEKLAEGIRNFTIDQVKLEKQLTDLL", "output": "Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway."}]}
+{"id": "function_test_1695", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKNKYDFKLVEEKRNEKWQKKGFFIAPKQTKKPFSIISPPPNVTGQLHLGHSWNAFIQDSLVRYHKLQGFDVLLLPSVDHAGIATQVKVEEDLAKKGIKKSDLKREEFIKKCYHWKEKQYLKIKEQWDKLGICYDFSKERFTLDQDAQIAVSDFFIKLWEKNLIYRGQKAINWDIKLQTAISNIEVINKPVEQKMYYLKYFLENSNEFLTVATTRIETISSDVALAINPKDKRYLHLVGKKVVHPLTKKLIIIIADSNVSSDFGSGIMKVSAHSILDFEIMEKHNLESKDCIDNYGNLNHEVPEFQGQNRFFARDLIAKKLEKEGFLAKIETVISNVGFSQRSDEIVEILKKPQWFVKMDELAKSLISHLNSKDKIKFYPKNFEKNLRKWFEKIHDWTISRQLWWGHRIPVWCKNDEFKVQIDSPGQGWIQDEDVLDTWFSSGISAFAFLGWPQNFDLIKSYFPTSLLVTGWDILFFWVARMYFSSLFIMKQKPFEKVLLHGLIRDEIGRKMSKSLGNGLDPMEIIEKYGSDTLRQALIFNSSPGKDIKFNIEKLNTAWNLNNKIWNIAKYIADLDTFFAKPDLIDLWMENKIYILKRQIVKNIKKYNFSVIGTEINNFIYGDFSSRYIELIKTRKNGFYARKLLRKVLIILHPFLPFLTDFLMEKIFKMEILEQKMPRIRQFKENQKVENILEIIDNLRTYREKFQISKKIILEYCIINDKFSNAEIDIINKLTFGKWLENKELVIKTKNFEIAIKVPEELKKEQKGRELKEIQFLKSEILRAEKILTNKGFLEKAPREKIDLERTKLEKLKEKLVFYEKK", "output": "Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner."}]}
+{"id": "function_test_1696", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MATILTLAGDGIGPEIMTQAIDVLNAVNNKFALGLTLESGLIGGVAVDATGEPLPEETLQRARAADAVLLGAVGGPKWDGIERSKRPERGLLKIRSELGLFANLRVAKLYPQLVNASSIKPEIISGLDLLIVRELTGGIYFGEPRGIRTLENGEQQGYNTMVYSTSEINRIGKVAFELAQTRAQAAGTPAKVCSIDKANVLEVTELWKQTMIELQQAEYSDVALSHMYADNACMQLIKDPKQFDVMVTGNLFGDILSDEAAMLTGSIGMLPSASLDEAGKGMYEPCHGSAPDIAGQDIANPLATILSVAMMLRYTFKQEVAAQAIEQAVSDVLDDGLRTVDILDRNEAGLIQVGCQQMGQAVLAKLL", "output": "Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate."}]}
+{"id": "function_test_1697", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSYALLRPFLFNMDPEHAHEMTLSLLDKAHKARVLGLVYGQSMQPTDCMGLQFSNPVGLAAGLDKNGDYIDALAELGFGFIEVGTVTPKPQVGNDRPRLFRLKQADAIINRMGFNNEGVDYLIENVKRCKYKGNIGINIGKNAATPVEQAADDYVYCLERVYPHASYITVNISSPNTKNLRDLQSGEALTHLLDAIKNRHSQLATEYGFYVPLVLKVAPDLDPLQVDYISQQLLDFEIDGLIATNTTLSRVGVEDLPDGDQAGGLSGRPVSHISTQILQQFSDQLDGKVALIGVGGIDSGAKAVKKIEAGADMVQLYSGLIYKGPGLVQSCIQSIGGYYDAMEN", "output": "Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor."}]}
+{"id": "function_test_1698", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSGISLGIPDGPPPVLAPRRKTRQLMVGGVGVGSDHPISVQSMTTTKTHDVNATLQQIAQLTASGCDIVRVACPKTVDAEALPAIAAKSPIPVIADIHFQPKYIFSAIDAGCAAVRVNPGNIKEFDGRVKEVAKAAGDAGIPIRIGVNAGSLDKRIMEKYGKATPEALVESALWEASLFEEHGYGDIAISVKHNDPVVMVEAYRQLAAQSDYPLHLGVTEAGPAFQGTIKSSVAFGALLAEGIGDTIRVSLSADPVEEIKVGDQILQSLNLRPRKLEIVSCPSCGRAQVDVYKLADEVTAGLEGMEFPLRVAVMGCVVNGPGEARDADLGVASGNGKGQIFVKGEVIKTVPEDQIVETLIEEAMRIAEEEGLEAVEGQKAEVRVTK", "output": "Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate."}]}
+{"id": "function_test_1699", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRPGSTPPSRRKSRPPRRVSPPLPTTSRTSPRRPHAQQQRRASRASPKKRFRPGTRALMEIRKYQKSTELLIRKAPFSRLVREVCMTYACGMNYNWQSMALMALQEASEAFLVRLFEDSYLCSLHAKRVTLYVQDIQLARRIRGVNEGLG", "output": "Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes. Replaces conventional H3 in the nucleosome core of centromeric chromatin that serves as an assembly site for the inner kinetochore. The presence of CENPA subtly modifies the nucleosome structure and the way DNA is wrapped around the nucleosome and gives rise to protruding DNA ends that are less well-ordered and rigid compared to nucleosomes containing histone H3. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. Required for recruitment and assembly of kinetochore proteins, and as a consequence required for progress through mitosis, chromosome segregation and cytokinesis."}]}
+{"id": "function_test_1700", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNDIWWQTYGEGNCHLVLLHGWGLNAEVWHCIREELGSHFTLHLVDLPGYGRSSGFGAMTLEEMTAQVAKNAPDQAIWLGWSLGGLVASQMALTHPERVQALVTVASSPCFSAREGWPGIKPEILGGFQQQLSDDFQRTVERFLALQTLGTETARQDARTLKSVVLAQPMPDVEVLNGGLEILKTVDLREALKNVNMPFLRLYGYLDGLVPRKIAPLLDTLWPHSTSQIMAKAAHAPFISHPAAFCQALMTLKSSL", "output": "The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters."}]}
+{"id": "function_test_1701", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKKQNNLRSLAAQAVEQVVEQGQSLSNVLPPLQQKVADKDKALLQELCFGVLRTLSQLEWLINKLMSRPMTGKQRTVHYLIMVGFYQLLYTRVPPHAALAETVEGAVSIKRPQLKGLINGVLRQFQRQQETLLNEFATSDARFLHPGWLVKRLQNAYPTQWQRIIDANNQRPPMWLRVNRTHHTRDGWLGLLEDAGMKGYPHPDYPDAVRLETPAPVHALPGFAEGWVTVQDASAQGCAVFLAPQNGEHILDLCAAPGGKTTHILEVAPEADVLAVDIDEQRLSRVYDNLKRLGMKATVKQGDGRYPAQWCGEQQFDRILLDAPCSATGVIRRHPDIKWLRRDRDIAELAQLQAEILDAVWPRLKPGGTLVYATCSVLPEENRDQIKTFLQRTPDAALSETGTPDQPGQQNLPGGEEGDGFFYAKLIKK", "output": "Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA."}]}
+{"id": "function_test_1702", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLKYFGTDGVRGVANQGLTPEMAFKLGRDGGYVLTKNKKDGEQAKVLVSRDTRISGQMLEYALISGLLSVGIEVLEVGVITTPGLSYLVRAQGADAGIQISASHNPVEDNGIKFFGSDGLKLSDEMEGEIEKLIDAEEDTLPRPSAEGLGTVTDFHEGSAKYLQFIENTIPEELDGIKVVIDGANGASSALISRLFADCGVDFTTIYTHPNGLNINDHCGATHTENLQKEVVKQGAQLGLAFDGDADRCIAVDENGNEVDGDHIMYVIGSYLAEHGRLKKDTIVTTVMSNLGFTKALEKEDLKNVRTQVGDRYVSEEMRAHGYNLGGEQSGHVIMSDYHNTGDGMLTGLHLMLVMKKTGKSLSELLKDFKDYPQCLVNVPVTDKKSWKEHQPILDVIAEVEKDMAGNGRVLVRPSGTQDLLRVMAEGPTQEETDAYVDRIVKVVEKEMGTNK", "output": "Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate."}]}
+{"id": "function_test_1703", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDIRPAEISDILKQQIASFDQVETVSETGTVLSIGDGIARVYGLTNVMAGEMVEFEGTGLKGMALNLEADNVGVVLFGDGDSIREGDTVLRTKSVVEVPVGKGLLGRVVDGLGNPIDGRGPLTDVEYRRAEVKAPGIMPRQSVSEPMQTGIKAIDALVPIGRGQRELIIGDRQTGKTAILIDTIVAQKPVNAEGDPKKSLYCIYVAVGQKRSTVANLVRTLIEHGAMEYSIVVAATASDAAPMQYLAPYTACAMGEYFRDNGMHALVCYDDLSKQAVAYRQMSLLLRRPPAREAFPGDVFYLHSRLLERAAKMSDANGGGSLTALPVIETQAGDTAAYIPTNVISITDGQIFLETDLFYRGIRPAVNVGGSVSRVGSAAQIKAMKQVAGKIKLELAQYREMAAFSQFASDLDAATRKQLDRGARLVELLKQPETSPLPVEEQVVVLYAGTRGYVDPIAVDKVVAYEAALLSELRGAGSDILTAIRNDRQIKPETEGKLKELLEAFGKRFSA", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit."}]}
+{"id": "function_test_1704", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MHNAIYTDLQKEVEVILARPRGFCAGVSRAIEIVKLAIEYYKDTKTIYVLHEIVHNKYIVETLKTMGVIFIDKVDQAQDGSVLIYSAHGVSKSIKQLAELRDLEVIDATCPLVNKVHKEVQLYDKSGYQVILIGHKGHREVEGTVGQISTPVIIVQNLNDIDKIEIFDPDKLAYVTQTTLSVDDTKVIIDKLKKKFPNIKGPDLKDICYATQNRQTTTKRLAELVDIVFILGSKNSSNSNRLKELAGIQTQAFLIDSYKEIDLNLLNDITKIGITAGASAPDILVQQVIDFLKQHMKVKLSDLEIVQESVTFNVPRQLRQYKEQYNPI", "output": "Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis."}]}
+{"id": "function_test_1705", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKVAVIKYNAGNIRSVDYALKRLGVEAVVTSDKEVLKAADKVIFPGVGEAETTMLHLKESGMDHFIKELRQPVLGICLGMQLMCRFSEEGNVDCLGIFDTDVKRFAPRKHEEKVPHMGWNTISCLKSDLFKGFTRDEFVYFVHSYYVPVSEFTAAETDYIRPFSAALHKDNFYATQFHPEKSGEAGERIIKNFLEL", "output": "IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF."}]}
+{"id": "function_test_1706", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTTETKSADIQLIQRILPHRYPFLLVDKVVEIDGYSSAVGIKNVTMNEPHFQGHFPGTPIMPGVTIVEAMAQTAGVMLGVGMDIIDSELLIYFMNIDNCKFRRKVVPGDVMKMHVETLRGKMGGKIFKFRGTATVEGEVAAQAEFSAYVDLTGEKST", "output": "Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs."}]}
+{"id": "function_test_1707", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGSSFGHLFRISTFGESHGGGVGVVIDGCPPRLEISEAEIQFELDRRRPGQSKITTPRKEADQCEILSGVVDGKTLDTPIAIVVRNKDQRSQDYSEMQVAYRPSHADATYDAKYGIRAVAGGGRSSARETIGRVAAGAIAKKLLREIAGVEIVGYVKRIKDLEGQIDPETVTLEQVESTIVRCPDEAIAPQMIDLIEAIGREGDSLGGVVECVARRVPRGLGEPVFDKLEADLAKACMSLPATKGFEIGSGFAGTEMTGSEHNDAFYTDEQGQIRTRTNRSGGTQGGISNGENIVIRVAFKPTATIRKEQETVTNSGEATTLAARGRHDPCVLPRAVPMVEAMVALVLCDHLLRQQAQCSWW", "output": "Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system."}]}
+{"id": "function_test_1708", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNDTLIIRELGRQPYEPVWHAMQEFTDQRDEHTADELWVVEHDPVFTQGQAGKAEHILAPGDIPVIQVDRGGQVTYHGPGQLVIYFLLNIRRLNYGVRQLVNHIENTVIETLSDYEIDAKARRDAPGVYVDTDKICSLGLRIRKGCSFHGLALNVNMDMEPFSRINPCGLSGIKMIQTKDLNGPDSFSEAADAVIKHFTSSLSYSNILQQTGLAQDYVKAS", "output": "Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate."}]}
+{"id": "function_test_1709", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGANQLVVLNVYDMYWMNEYTSSIGIGVFHSGIEVYGREFAYGGHPYPFSGIFEISPGNASELGETFKFKEAVVLGSTDFLEDDIEKIVEELGKEYKGNAYHLMHKNCNHFSSALSEILCGKEIPRWINRLAYFSSCIPFLQSCLPKEWLTPAALQSSVSQELQDELEEAEDAAASASAASTAAGSRPGRHTKL", "output": "Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization."}]}
+{"id": "function_test_1710", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAIRKKSTKSPPVLSHEFVLQNHADIVSCVAMVFLLGLMFEITAKASIIFVTLQYNVTLPATEEQATESASLYYYGIKDLATVFFYMLVAIIIHAVIQEYMLDKINRRMHFSKTKHSKFNESGQLSAFYLFACVWGTFILISENYISDPTILWRAYPHNLMTFQMKFFYISQLAYWLHAFPELYFQKTKREDIPRQLVYIGLYLFHIAGAYLLNLNHLGLVLLVLHYFVEFLFHISRLFYFSNEKYQKGFSLWAVLFVLGRLLTLILSVLTVGFGLARAENQKLDFSTGNFNVLAVRIAVLASICITQAFMVWKFINFQLRRWREHSAFQAPAVKKKPTVTKGRSSKKGTENGVNGTLTSNVADSPRNKKEKSS", "output": "Involved in the translocation of nascent protein chains into or through the endoplasmic reticulum (ER) membrane by facilitating the proper chain positioning at the SEC61 channel. Regulates the exposure of nascent secretory protein chain to the cytosol during translocation into the ER. May affect the phospholipid bilayer in the vicinity of the lateral gate of the SEC61 channel, thereby facilitating ER protein transport. Intimately associates with transmembrane (TM) domain of nascent membrane proteins during the entire integration process into the ER membrane. Associates with the second TM domain of G-protein-coupled receptor opsin/OPSD nascent chain in the ER membrane, which may facilitate its integration into the membrane. Under conditions of ER stress, participates in the disposal of misfolded ER membrane proteins during the unfolded protein response (UPR), an integrated stress response (ISR) pathway, by selectively retrotranslocating misfolded ER-membrane proteins from the ER into the cytosol where they are ubiquitinated and degraded by the proteasome."}]}
+{"id": "function_test_1711", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDLENKVKKMGLGHEQGFGAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFEDTKYTTLIAKLKSDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFVKKYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHKRTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNFSWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKRMS", "output": "Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor (By similarity)."}]}
+{"id": "function_test_1712", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVGEMETKEKPKPTPDYLMQLMNDKKLMSSLPNFCGIFNHLERLLDEEISRVRKDMYNDTLNGSTEKRSAELPDAVGPIVQLQEKLYVPVKEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKEEQNRGKPNWEHLNEDLHVLITVEDAQNRAEIKLKRAVEEVKKLLVPAAEGEDSLKKMQLMELAILNGTYRDANIKSPALAFSLAATAQAAPRIITGPAPVLPPAALRTPTPAGPTIMPLIRQIQTAVMPNGTPHPTAAIVPPGPEAGLIYTPYEYPYTLAPATSILEYPIEPSGVLGAVATKVRRHDMRVHPYQRIVTADRAATGN", "output": "RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity)."}]}
+{"id": "function_test_1713", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLYWLTQLLQGQYHAFRVFQYLTFRSILASLTALIVGLLCGPLMIRWLRGLQIGQMVRSDGPQTHLSKAGTPTMGGVLILLAITVSCLLWCDLRQTSLWLVLLVTLANGLVGWVDDYRKLVLKNSKGLPGRWKYFWQSVIALVAVSYLYWNASLPVHTQLTVPFFKTVTWDLGVFFPVLAYFVIVGSSNAVNLTDGLDGLAIMPIVMVAGALGVFAYASSNAVYSNYLGIPYVPNTGELTIFCSSIVGAGLGFLWYNSYPAQVFMGDVGSLALGAALGIVAIVVRQELVLLIMGGLFVIETLSVILQVGYFKYSGGKRLFRMAPLHHHFELKGWSEPKVIVRFWIITVVFVLCGLATLKLR", "output": "Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I."}]}
+{"id": "function_test_1714", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAWFSLHLLHLLWAAAGTSTWARSSCSVPQAAQHLVDGLQVLLEDSVSSAAPPNPSVLIAMNLAGALSAEARELLADRLGASDSAGLSVGQLALTIMALNSSCRDPGNKVSVLYGQMEAWPPSSPSAPAWTFYGPSLAVLALCQEHPGRALPVAARLAKILAAGLSPFNTDTGAMVTLALTCMYNKIPEGSEEGYRTLFSQVLKDVVENISMRIKDNGIIGDVYSTGLAMQALSVTPEPPNKEWDCKKTMDTILKEIEQGKFHNPMSIAQILPSLKGKTYLDVPYVSCSPGHQVQPTLPSQPSPVPTSASNITVAYTINNQLKGVELVFNETIDVSVKDGSVLLVVLEEAQRRNPMFKFVTTMTSWGLVVSSINNIAESVHDRTYWQFLSGKTPLNEGVADYTPRDHEHITANFTQY", "output": "Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the CBLIF-cobalamin complex is internalized via receptor-mediated endocytosis (By similarity)."}]}
+{"id": "function_test_1715", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNLAAYYPVLLFLLVGTGLGIALVSIGKILGPNKPDSEKNAPYECGFEAFEDARMKFDVRYYLVAILFIIFDLETAFLFPWGVALREIGWPGFIAMMIFLLEFLLGFAYIWKKGGLDWE", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_1716", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPMSRPDSAVSLLPDYSLRAHNTFGFDARARVAARIGSPGQFASLARDPRVAGLDRLVLGGGSNVVFTRDFDGLVLLDEIRGRALVREDDGAWYVEAGGGENWHAFVEWTLAEGMPGLENLALIPGTVGAAPIQNIGAYGLEMKEHFASLRAVELATGELVEFDAARCAFGYRDSFFKRDGRGRFAIVAVTFRLPKAWTPRIGYADVARELAARGIDARAARARDVFDAVVAIRRAKLPDPLALGNAGSFFKNPVIDAQAFAALRAREPDIVSYPQPDGRVKLAAGWLIDRCGWKGRALGAAAVHERQALVLVNLGGASGADVLALAHAIRRDVLGRFGVELEMEPVCL", "output": "Cell wall formation."}]}
+{"id": "function_test_1717", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTTLADLRTNYSRASLDAADVNPNPFVQFDVWFKEALDAQLPEPNTMTLATVDESGRPSARIVLIKGADERGFVFFTNYESRKGRELAHNPNAALLFYWIELERQVRVEGRIEKTSEEESDRYFASRPLGSRIGAWASEQSAVIESRALLEAREKEIGARFGENPPRPPHWGGYRLVPSSIEFWQGRPSRLHDRLLYTRDAASASGWKIARLAP", "output": "Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)."}]}
+{"id": "function_test_1718", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVVAVYPGTFDPLTRGHEDLVRRASSIFDTLVVGVADSRAKKPFFSLEERLKIANEVLGHYPNVKVMGFTGLLKDFVRANDARVIVRGLRAVSDFEYEFQMAGMNRYLLPDVETMFMTPSDQYQFISGTIVREIAQLGGDVSKFVFPSVEKWLTEKVAAMAQGPSA", "output": "Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate."}]}
+{"id": "function_test_1719", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKALSKLKAEEGIWMTDVPQPELGHNDIMIKIRKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVAIGQEVKGFNIGDRVSGEGHITCGHCRNCRGGRTHLCRNTVGVGVNRPGSFAEYLVIPAFNAFKIPDNISDELAAIFDPFGNAVHTALSFDLVGEDVLVSGAGPIGIMAAAVCKHVGARHVVITDVNEYRLDLARKMGVTRAVNVSKENLNDVMTELGMTEGFDVGLEMSGAPPAFRSLLNSMNHGGRIAMLGIPPSDMSIDWNQVIFKGLFIKGIYGREMFETWYKMAALIQSGLDLTPIITHRFPIDEFQQGFDAMRSGKSGKVVLSWD", "output": "Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate."}]}
+{"id": "function_test_1720", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRTPIVAANWKMHKTQPEARQFLADFLPREAGMSGVEIVICPPFTALAAVAGGLTGTRVGLGAQNMSDKPSGAFTGEVSGAMLVDAGCRYVILGHSERRRLFGESDEVVGAKVRAALQHGLIPILCIGETLEEQQAGEADAVNRRQLLAGLEGLTPEQVANLVIAYEPVWAIGTGRNCDPGDAQARIAAVRAVVAEAFGPEAAARVRIQYGGSVKPENMAAYMAQPDIDGALVGGASLDPTSFAAICAAAAEARAR", "output": "Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)."}]}
+{"id": "function_test_1721", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAEGDYNAVREAIADILDNDDYDDGSIGPVLVRLAWHASGTYDKATGTGGSNGATMRYMKEAKDEANNGLENARQFLEPIKAKFPWITYADLWTLAGVVAIEEMDGPKVPWKPGRQDYVDETNVPPNGRLPDGAQGQDHLRDIFYRMGFNDQEIVALCGAHNMGRCHMDRSGFEGAWVPNPIRFANTYFKLLMNEEWKLTTLKNGVKQYFNEDEELMMLPADYSLMQDPEFHKWVEIYAADKEKFFEDFSKVFAKLIELGVRRGPDGKAKTNFIDRNNNDPNPRL", "output": "Destroys radicals which are normally produced within the cells and which are toxic to biological systems."}]}
+{"id": "function_test_1722", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSADCSVGSNPLAQLNKHAQQNPALRQVGYQNPASNVAQNFKTHVNEVSNANRFQMDQFMNRSPGFSDGQLGMAPVPSAILSHGPRFGLKKQDSGSSNMSAGDTAQHSRSWGNEFNSRSPQQGLASRVNNVERISNTNSMSSYRPGMSRIGRPMMHTGISSLHNYSHMSQQTPQMSSDDGVLADKQWNEQFEALEKAVAENLTMEDNKEETKEEIVVEDGYQADFQEVWDKLQAETADNNLETSDSQWEKDYARYMTGKATHIPPYRFDNDNQYMHNPNAYEIGCILMENGAKLSEAALAFEAAVQEDPAHVDAWLKLGLVQTQNEKEMNGISALEQCLSLDPTNQQALMTISISYINEGYDLTAFSMLNRWLDSKYPELTRSPTIDEANIDRFNLSKQVITKYLQVANALPQVDPEVQLGLGTLFYANEEFGKTIDCFRTALEVNPNDELMWNRLGASLANSNRSEEAIQAYHKALALKPSFVRARYNLAISSMNIGCYKEAAESLLSALSMHEVENVPITGSVVQSNNILETLKRSFVAMDRRDLLEKVMPGMDLQQFRNEFNF", "output": "Receptor that mediates peroxisomal import of proteins containing a C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type). Binds to cargo proteins containing a PTS1 peroxisomal targeting signal in the cytosol, and translocates them into the peroxisome matrix by passing through the PEX13-PEX14 docking complex along with cargo proteins. PEX5 receptor is then retrotranslocated into the cytosol, leading to release of bound cargo in the peroxisome matrix, and reset for a subsequent peroxisome import cycle."}]}
+{"id": "function_test_1723", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MHTKVLQQGLWALLLWPHLFTVSVPLDCRDDQASLARCPSISQEKLLDRVIHHAELIYRVSEESCSLFEEMFIPLPLRLQSNQGGYACITKALPIPSSKSEIQQLSDKWLLHSVLMLVQSWIEPLVYLQMTLDRYDHAPDMLLNKTKWVSEKLISLEQGVVVLIKKMLDEGAMTTTYSEQGAFQYDVQLEMLEYVMRDYTLLTCLKKDAHKMETFLKLLKCRQTDKYNCA", "output": "Selectively regulates proliferation and morphogenesis of neural-crest derived pigment cells."}]}
+{"id": "function_test_1724", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNNSGSGGSSPFVESPDLVSDGHLHTERKDTPIDVDNWKYKYDNLLNQYEIEKVRWQKEQYDSEKSHEALHLQLEKARNEIDQLVESKRFLEAQLQSQHPQNTQKEWSHEDNKVNNNSMNNDYMLLEEKYKSDVFHLDNSVNELKLELTSCRSLLKKYEEVIEQQSEQIKEIKKTLKKKEQELDEIEVNRLKQAHNATNTEEIRQQTNENASFSNGYNTLMSMKNSVNYWKNENQQLNQKLSEYSDIYQQLQEAQLEIMELKANLEEWNKFLSNKKQQDNSNDYSIDHFIIEFESQRRELNMVTEELAEVKKSYYNSKILNDELALERNQLLKLKDDYENNIINLEKLNHELEQQKVLLEEECSLLKNQIPTKENLNQQIRSTNRNDAEYDSLLDNYKQETENLTNELKRLNDSLIEQNRNQGTEMKKRKLRNGDHININYSQRLNELQQNNLSLEKDNEKLRLVVEKLEGKLDDLRKTKPKNIRILQQRDSPLLKLQFVRRKENELLREENQNLLTMIENITENRNESFDKIPLTSYNSLKYQYEISMDTNKKQEKKFSRLKQIFNKKSLEFIDVVNSLLGFKLEFQQDGRVKIYSCYMPNKYLIANLVDNTLKSNLDTVISDWDSLLNDWVVEKGQLPCFLASLTLQLWKMENDS", "output": "Central component of the spindle assembly checkpoint."}]}
+{"id": "function_test_1725", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTKLITTVKEMQHIVKAAKRSGTTIGFIPTMGALHDGHLTMVRESVSTNDITVVSVFVNPLQFGPNEDFDAYPRQIDKDLELVSEVGADIVFHPAVEDMYPGELGIDVKVGPLADVLEGAKRPGHFDGVVTVVNKLFNIVMPDYAYFGKKDAQQLAIVEQMVKDFNHAVEIIGIDIVREADGLAKSSRNVYLTEQERQEAVHLSKSLLLAQALYQDGERQSKVIIDRVTEYLESHISGRIEEVAVYSYPQLVEQHEITGRIFISLAVKFSKARLIDNIIIGAE", "output": "Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate."}]}
+{"id": "function_test_1726", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MANIVFKLSDKDITTLMSRITFDTENLPQGMKARAKYQNTTVNIYQSGKVMFQGNHAEAVSKELLPQHSQLNTNKTKKKNMANSFLEQTLMYDQFNCIGSDEAGSGDYFGPLTVCAAFVTKEHVPILKTLGVDDSKKLTDTKIVELADQLVTFIPHSLLTLHNEKYNIQQAKGWTQVKMKAVLHNEAIKNVLEKIDSSQLDYIVIDQFAKREVYNHYALSDIPLPKKTKFETKGESKSLAIAVASIISRYAFVTYMDQISKNINMTIPKGAGAKVDVIAAKIIKKYGLSHLDTISKKHFKNREKAQKILKPL", "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."}]}
+{"id": "function_test_1727", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGNFHATTIFAVHHNGECAMAGDGQVTMGNAVVMKHTARKVRKLFQGKVLAGFAGSVADAFTLFEMFEGKLEEYNGNLQRAAVEMAKQWRGDKMLRQLEAMLIVMDKTTMLLVSGTGEVIEPDDGILAIGSGGNYALSAGRALKQYASEHLTAKQIAKASLEIAGDICVYTNHNIIVEEL", "output": "Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery."}]}
+{"id": "function_test_1728", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNQTLNSSGTAELALNHSRGSVVHAACLVLSSLAMFTCLCGMAGNSMVIWLLGFRMRRTPFSIYILNLAAADLLFVFCMAAMLSLETQPLVSTTDKVHELMKRLKYFAYTVGLSLLTAISTQRCLSVLFPIWFKCHRPRHLSAWVCALLWMLCLLTNGLTSCFCSKFLKFNKDQCFRVDMVQAALIMGVLTPVMTLSSLTLFVRVRRSSQQWRRQPTRLFVVVLASVLVFLICSLPLGFYWFVLYWLNLPPDTKVLYFNLSRLSSSMSSSANPLIYFLVGSRRSRRLQGSLGTVLQRALREEPELEGGETPTTGTNEMGA", "output": "May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. The receptor couples with G-protein G(q) and G(i) (By similarity)."}]}
+{"id": "function_test_1729", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSILALVEDRPTPKEVYNWKIYLLAAVASFTSCMIGYDSAFIGTTLALSSFREEFGFSTMSKTAVNLVSANIVSCYQAGAFFGAFFAYPIGHFWGRKWGLLFAGTIFTLGAGLMLGANGDRGLGLLYGGRVLAGLGVGAGSNITPIYISEMAPPSIRGRLVGVYELGWQIGGLVGFWINYGVSETLAPSHKQWIIPFAVQLIPSGLLLIGAVFLKESPRWLFSRGRREDAIKNLCWIRQLPADHIYMIEEIGAVDQALEEQRTTIGLGFWKPFKAAGTNKKVMYRLFLGSMLFFWQNGSGINAINYYSPTVFKSIGLHGANTSMFSTGIFGVVKTVVTFVWLLYLIDRVGRRLLLLIGAAGAAVCLLIVGAYIKIADPASNPTQEMTGGGIAAMFFFYLYTVFYTPSWNGTPWVMNSEMFEPNMRSLAQACAAASNWLWNFLISRFTPQMFAKMEYGVWFFFASLMLLSIVFVFFLVPETKGIPLESMDVLFESKPIWRAHATVLAKLREDEEQFRHDIEESGYSKTGEQQVEHVSEDLPKV", "output": "Integral membrane transporter that imports quinic acid to be catabolized as a carbon source."}]}
+{"id": "function_test_1730", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSKTPRKSAPSPSLQLGQAVEWPDRPEAAKLDRVPNPQKDTNFLARFTAPEFTSLCPVTGQPDFAHLVIDYVPGPWLLESKSLKLYLASFRNHGAFHEDCTVAIGKRIATEIKPKWLRIGGYWYPRGGIPIDVFWQTGKLPKDVWVPDQGVQPYRGRG", "output": "Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)."}]}
+{"id": "function_test_1731", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAMAINVKKWIEENTEYFLPPVCNKLMHNQQLKVMFVGGPNQRKDYHIEEGEELFYQVEGDMCLKIVENGKHKDVHIKQGEMFLLPGRIPHSPQRYADTVGLVFERRRLDTEKDGLRFYVEGSPEVLFEQWFYCEDLGTQLAPIMKEFFSSKQYKSGKPDPDQPKAKMPFCLSTEQVMEPFSFQHWLNKHRLEIIQKKCVSLFGDDHETKAVIYGGGESKQSKAQTDVWIWQLEGTSHVTLGNEVLKLGSGDSLLVPEETLFSWTREDGSIALSTSQVPLPM", "output": "Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate."}]}
+{"id": "function_test_1732", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTIALGRFSKEENDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFALGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFGLIGFMLRQFELARSVQLRPYNAIAFSAPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL", "output": "Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors. D2 is needed for assembly of a stable PSII complex."}]}
+{"id": "function_test_1733", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKRKIIVGSRRSKLALTQSNWVINKLKENYPEFDFEIKEIVTKGDRILDVTLSKVGGKGLFVSEVEQALSDEVIDFAVHSMKDVPSSLKEGLIIGAIPKRESPLDCFVFNRVNSLDELPQGSVIGTSSLRRAAQLLKHRPDFVIKPIRGNIDTRLQKLHAENFDAIILAKAGLARMGWLENTTLKLEDIPPELCLPAVGQGALAIECRESDQQIRDMLTSIHHEETGICVEAERVFLKKLNGGCEIPIAGFATRANEVVHFKGLVGNADGSIILASEQAGANPSEIGNKVAEDLLSEGADTIIKELRNI", "output": "Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps."}]}
+{"id": "function_test_1734", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLCGIDEAGRGPLAGPVTAAAVILPSSFDFSILKDSKKLTEKKREEVRKTIYADPNVIWAIGWASNYEIDEINILQATFLAMERAYEGLYLKLQEFCKLNNDKFIEPDIIVDGNFIPNIKNCSSIKALVKADDSVYEVMAASILAKTARDRMMIRYSWIYPEYGYEKHKGYGTKKHIEAIRFNGYSPIQRRSFFVKNL", "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."}]}
+{"id": "function_test_1735", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLTDRLRLKKARKLLNKINKLGPKMQAMSDEKLQGQTAIFKKQLKEGKSLDDILPEAYATVREADKRILGMFPYDVQVLGAIVLHNGSIAEMKTGEGKTLVATMALYLNALEGKGAMLVTPNGYLASRDKKELAPVYEWLGLSVSLAFAEEKDSKKKITAKTKRKWYNSDIVYTTASSLAFDYLFNNLASSKENQYLRPFNYVIVDEVDEVLLDEAQTPFVVSSSPNVQSNLYHLADQFVRLLDPEVDYVFKKDDQLFWLTAHGIEKAEQFFKLDSLFSNESRSVYRHIILAMGAHLTMRRGHDYLVVKGEVVLLDEDSGRLKRGVQVSTGIHQAVEAKEKVELTKIQKTAASITFPALFALFNKVSGMSGTAKVNEEEFLQTYNLKVVTIPTRVPVIRKDYRPLIFLTTIDKLMTAVDDVVEMHKTGRPVLLVAGSVENSEIISELLLNIGIPHNVLNAYNAAYEAQIIKNAGQKNAVTIATNMAGRGTDIKLGPGVKELGGLAVIGTEMLPKRVELQLAGRAGRQGDPGSSQFLISLEDSFISSNNTPRQKKYYRKLMKKKSKGKDITLLSGPRIRFSLLMLRTRKEDLNELMRSQTNKMEIILSLQRKNFYTRRDKIMKTDDLQEDVDRIIDNALNLYLEKQDLSNKSDLKYFINQHVTYQQVNVPDNLKTKKAIKDFLKELAYKILDEKKHVLINKKQANDFYQQVIISSMDGNWIDQVDRIEKIKINAQQWGRSGRPQDLLHQEKAFEAYKDFLDKITLSTFDNLLLSKIFTNEKGQLVVVFN", "output": "Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane."}]}
+{"id": "function_test_1736", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNSDTLNIGNKIFQSRLIVGSGKYKDFKTTYEATMASEAEMITVAVRRVNITNPKEENLLDYFKGSSVQFLPNSAGCTTAEETITLFRLTREATGIDFIKLEIIGDTQKTLYPDVMETLKACEVLAKDGFTVLAYTNDDPIMARRLEEAGASAIMPLAAPIGSGLGIQNRYNVVFIKEAIKVPLIVDAGVGCASDAAIAMELGADAVLTNTAIAQAQNPILMASAMRDAVRAGRQSYLAGRIPKKPYASASSPTDGMARF", "output": "Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S."}]}
+{"id": "function_test_1737", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MHKTAIYPGTFDPLTNGHMDIIRRASMIFDTLIVAVAKSATKEPMFPLSEREEMLRLATRECPSVRVESFDTLLADFAQERGACILVRGLRAVSDFEYELQMGYANASLNPALETIYLMPSLQNAFISSSVIRSILLHKGKISHLVPPVVCEYIQKRRSCM", "output": "Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate."}]}
+{"id": "function_test_1738", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTHKPCLLYSQLPAIDRLLREPQITPLVEQYGQTLVTATLRRMQEQARINIKQYQALPDWCDNWASALGQQLEQKQALALKPVFNLSGTVIHTNLGRALMAESAIEAVTQVMRSPVTLEYSLNNAERGHRDHALADLLCELTGAEDACIVNNNAAAVLLLLATVASGKQVVVSRGELVEIGGAFRIPDVMVQAGCRLVEVGTTNRTHLKDYRQAINEETALLMKVHTSNYNIDGFTAEVSGRELATLGIASQIPTAIDLGSGSMINMVQYGLPAEPMPQDYLNQGIDLVTFSGDKLLGGPQAGIILGKKHWIEAIQRHPLKRALRADKMTLAALEATLRLYQRPEQLCQQLPTLRLLTRSQQQMHDMAQRLLPQLQAHYGDQFIVRDEPCYSQIGSGSLPVDRLPSWALTFAAVEGQGSSLERLARCWRGLAKPVLGRISGGRLWLDLRCLEDEKALLQALLL", "output": "Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis."}]}
+{"id": "function_test_1739", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAIPVVVVGCAGKMGREVVKAVHAAPDMAVVGAVDRSHIDEDAGELAGIGPIDVLVTDNLEITCAMVAQERAPGVMVDFTHPRGIYDRVRSAIAYGVRPVVGTTGLPPEHIEELAEFADKASTGCIVAPNFAIGMILLQQACLRAAEYFDHVEIIELHHNRKADAPSGTALATAQMIATTGKTFNVPEVSESELVAGARGGMTPGDIRIHSLRLPGLLAHQAVIFGGLGQSYTLRHDTTDRAAYMPGVLLAIRKVLGLKSLVYGLEKII", "output": "Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate."}]}
+{"id": "function_test_1740", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLKTLKDKKLENCSSINNKSKKQQKIIVGLSGGVDSSLSAALLIEDGWKVEGLTLWLMKGEGSCCSEGLVDAAGLCEDLGINHNILDSRVIFEREVVKKTTEGYESGFTPLPCSMCNKNVKFEEMLNFVIKQKEFTYIATGHYARVQKVSCENIKNYENFQFKDFLLLRGADRNKDQSYFLYSLSQEVLSRLILPLGNLKKEETRKEALRLGLRTAKKPESQDLCLVEHYGSMQKFIDNHIEPKEGEIKHINGEILGTHNGIQHFTIGQRKGLGIAWPEPLYVESLDKQKNIVYVANKKDLFKREAIIKEINWVSIEAPLKEIEVEAQIRYRSEPVKGILVPVKNEDNLTKKFKLIFEDNQSSITPGQAAVFYKDEILLGGGLICEFSKI", "output": "Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34."}]}
+{"id": "function_test_1741", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQKLVLGVEYDGSMYCGWQKQKCVSSIQSCLEYALSKVSSESILVFCGGRTDSGVHALEQIVHFETQLKCSRSAWTLGVNCHLPNDICVRWVSEVDNSFHARFSAISRRYCYFIYNNRIRSAVFCKRVWSYSRFLDVNKMSKAAQYLLGENDFSVFRSSGSQSCSTNRNIYHLRVIRQGHYVVIDIRANAFLYRMVRNIVGSLVEVGCGNKPVTWILELLKNYRGSLNRITAPASGLYLVEIKYPRYYLFQK", "output": "Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs."}]}
+{"id": "function_test_1742", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSQNLILILNCGSSSLKFAILDPINGDEKLSGLAESFYLDDARIKWKFNGEKGNADLDAGAAHTEALNFIVSNILTDELKQSIGAIGHRIVHGGEKFTSSVVITDEVVKGIEEVIQFAPLHNPAHLIGIQEAFRIFPELKDRNVAVFDTAFHTTMPEQAYLYALPYSLYKDHGVRRYGAHGTSHYFVSREAARRLNVAEDKVNVITCHLGNGGSVSAIRHGECIDTSMGLTPLEGLVMGTRSGDIDPAIIFYMHDTLGMSVEEINNTLTKKSGLLGLTEVTSDCRYAEDNYETDDAARRAMEVYCYRLAKYIGSYMAVIGERLDAIVFTGGIGENSAHVREITLNHLKLFGYQVDDARNLAARFGNEGVITAEGSPLAMVIATNEELVIAQDTARLTITK", "output": "Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction."}]}
+{"id": "function_test_1743", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRFDKLTTKFQQALADAQSLAARNDHPYIEPVHVLAALLGDPDSGAASLLARAGVAVNRVQPAIDSALKGLPQVQGDDNVQVGRELQSVLVRTDKEAARRGDTYIASELFLLALADDKGDAGRILREAGLQKKALEAAIDAVRGGENVSGAEGESNREALSKYTLDLTERARQGKLDPVIGRDDEIRRTIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNDEVPETLRGKRVLSLDLAALLAGAKFRGEFEERLKAVLKELAQDDGQNIVFIDELHTMAGAGKAEGAMDAGNMLKPALARGELHCIGATTLDEYRKYIEKDAALERRFQKVLVGEPDVESTIAILRGLQERYELHHGVEITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAGARIRMEIDSKPEVMDRLDRRIIQLKIEREAVKKETDDASMRRLAVIEEELEKLQREYNDYEEIWKAEKAAVQGTQAIKEEIDRVRAEMAELQRKGQFDKLAELQYGKLPELEARLKAADSAEREAGESDSGKPRLLRTQVGAEEIAEVVSRATGIPVAKMMQGERDKLLRMEDFLHKRVVGQDEAVRLVSDAIRRSRAGLADPSRPYGSFLFLGPTGVGKTELTRALADFLFDSEEHMIRIDMSEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTVIVMTSNLGSQHIQSMAGKPYEVIKEVVWDELKHTFRPEFLNRIDEVVVFHGLEAQHIESIARIQLKRLGERLEKQEMRLDVSDAALAEIARSGFDPVFGARPLKRAIQQQIENPVAKLILEGVFGPRDVVPVDWQDGKFVFTRTLQ", "output": "Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity)."}]}
+{"id": "function_test_1744", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSKQFGKVGVLYGGRSAEREVSLMSGKGVHEALLSAGVDAHLFDTGERSLADLAAAGFERVFIALHGRYGEDGTLQGALELLGIPYTGSGPLASSLSMDKIMTKRVWLQHGLPTPAFEVLGGSTELRLVPDRLGLPLILKPPHEGSTVGITKVAGYSDMKAAYELAARFDAEVLAEQFITGRELTVAVLGSGAAARALPVIEIVAPGGNYDYEHKYFSDDTQYFCPADLPADVAADVAAVAERAYAALGCEGWGRVDFILDRENRPWLLEMNTSPGMTGHSLVPMAARAVGMSYADLCVAILAKAACKVRSPARQD", "output": "Cell wall formation."}]}
+{"id": "function_test_1745", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MXXXXKSXXQXKIXXXXXIDXXXXSKMTSWWNLGSLLGICLRLQILTGLXLAMHYTSDTATAFNSVTHICRDVNYGWVLRYMHANGASMFFICLYLHVGRGLYYGSYMFSETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTNLVEWIWGGFSVDKATLTRFFAFHFLLPFIISAMVMVHLLFLHETGSNNPTGIPSNIDMIPFHPYYTIKDILGLLLIIMMLMMLVLFSPDMLGDPDNYMPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVVALVLSILILAIIPLLHTSKQRSMIFRPLSQCLFWLLVADLLTLTWIGGQPVEHPYIMIGQLASIMYFSIIIILMPLTSLMENHLLKW", "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."}]}
+{"id": "function_test_1746", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTHPSDTGPAPVLALEDISKSFGAVRALRDVSLELFPGEVHALAGENGAGKSTLIKTLAGVHRPDAGQVLLDGRPTVFHGPADARDAGIAVIYQEPTLFPDLSIAENIYMGRRPRRSFGRIDHKATRAATAALMRRLGVELDPERPARGLSIADQQIVEIAKALSFDARVLIMDEPTAALTGSEVARLFGVVRTLREQGAAVLFISHRLEEIFQICQRVTTLRDGALISSEPLDGMTEDDLVRRMVGRDLDELYPKQEVRAGEVAMSVRRLTREGVFTDVSFDVRRGEIVGLAGLVGAGRTEVARAVFGIDRWDAGEVEVEGRRLTNGAPSTAMAAGLALVPEDRRAQGLVMNMSIERNIGLTGLRTTVRAGLVDRGAERSRSLDWAAKLQVKYARIADAVSTLSGGNQQKVVLAKWLATGPRVLIVDEPTRGIDVGTKAEVHRLLSALAADGVAVLMISSDLPEILGMADRVLVMHEGRVTAEIPRSEATEESVMAAATGRAAA", "output": "Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system."}]}
+{"id": "function_test_1747", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAKESIQAIKEALLTVTDATDERLASWREDERSGVQQAIKQWERRQLAKEKEWQLFKEMSQFEEAAYKKGHRLIAGIDEVGRGPLAGPVVTAAVILPKDCQLLGLNDSKKLSAKKRETLYNQIQEQAVAIGLGIADQGVIDQINIYQATKQAMKMAIDDLAFTPDYLLIDAMQLDVPQPQESLIKGDARSISIAAASIIAKVTRDRLMEEYDELYPGYGFKNNAGYGTKEHLLGLEKYGVTPIHRRTFAPIKDMI", "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."}]}
+{"id": "function_test_1748", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSCYTAILKSVGGLALFQVANGAIDLCRHFFMYFCEQKLRPNSFWFVVVRAIASMIMYLVLGIALLYISEQDDKKNTNNANTNNDSNSNNSNNDKRNESSINSNSSPK", "output": "Envelope protein. Required for an early step in virion morphogenesis."}]}
+{"id": "function_test_1749", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIYQEENQHLRIGLASPEEIRGWAERTLPNGEVVGRITEPYTLHYKTHKPEKDGLFCERIFGPIKSGICACGKYRSIENQREYSKICEQCGVEFTESRVRRYRMGYIELACPVTHVWYLKRLPSYIANLLAKPLKELESLVYCDLFLARPIAKKPTLLKLRGLFKYEDQSWKEIFPRFFSPRGFEAFQDREVATGGNAIEKGLASLNLQIVMDRAYMEWRNLTEQKSTGNEWEDRKIQRRKDLLVRRMELAKNFLQTNMKPEWMVLSLLPVLPPELRPMIELGEGELITSDLNELYRRVIYRNNTLLDFLARGRSTPGGLVVCQKRLVQEAVDALIDNGIRGQPMRDSHNRAYKSFSDLIEGKEGRFRENLLGKRVDYSGRSVIVAGPYLPLHECGLPKEMAVELFQAFVIRGLIGRYLAPNLRAAKSMIQDKEPIIWKILKEVIQGHPVLLNRAPTLHRLGIQAFEPILVEGRAIRLHPLVCAGFNADFDGDQMAVHIPLSLEAQVEARLLMFSHTNLLSPVTGNPVSVPSQDMLLGIYVSTIRSNRGIYQNQYHPYDYRNKNFSYKMFYFHSYDDILKAEKQKQINLHSPLWLRWQVDLHIVTSIDREVPIEIQYESLGTSSQIYENYQFRKNRKEKILSMYICTTAGRILFNQQIEEAIQGFFEVSQHRSRPLPAIIA", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_1750", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MANALGFRDLGLIDYETAWHAMQRFTDGRGREAGDEVWLVQHPPVFTQGQSGKAEHLLLPGNIPVVQVDRGGQVTYHGPGQLVAYLMLDVRRLGFGVRDLVTRIENTLIALLADYGVTAAAKADAPGVYVDGAKIASLGLRIRNGCSFHGLALNVDMDLEPFRRINPCGYAGLAMTQLSDQAGQIEFSEVSVRLRAQLVKHLDYAEQATLTGGINQYD", "output": "Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate."}]}
+{"id": "function_test_1751", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTPAPPFLQATALACERDWRVLFENLDLHLCAGDMLQVSGPNGSGKTSLLRLLCGLMQPTAGQVLLNGQVLGRQRAPGCDLLWLGHAPALKDLLTPLENLAWLCALHQPAGADAIGHALNAVGLAGFEDVPCHTLSAGQQRRVALARLHLPGPSLWILDEPFTALDQQGIAQLENHLADHCEQGGMVVITTHHTLSRLPAGYRSIDLAKGSA", "output": "Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system."}]}
+{"id": "function_test_1752", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTHSNRMLLGVNIDHVATLRQARGTRYPDPVKAALDAEEAGADGITVHLREDRRHIQERDVVLLKDVLQTRMNFEMGVTEEMMAFAEKIRPAHICLVPETRQELTTEGGLDVAGQEARIKAAVERLARTGAEVSLFIDADERQIEASRRVGAPAIELHTGRYADAETPTEVAEELKRIVEGVAFGVGHGLIVNAGHGLHYHNVEAVAAIKGINELNIGHALVAHALFVGFKAAVAEMKALIVAASR", "output": "Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate."}]}
+{"id": "function_test_1753", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNHYKDFISNLIENLGSENVKTNELMKNHTSFKVGGPVDILVTPESYEQVQYVIKHSRGNNIPYFIMGNGSNLLVRDGGIRGLVIKFCKLNRIKIEDDKIIAQSGVLLSKVSNMAAKNNLEGLEFASGIPGSIGGALTMNAGAYNGEISQVIDSALVLDKSGEILNLSKEELELGYRTSSILKNGYVVLEAILKLSLGDSKNIYDRIKELTEKRKTKQPLEYPSAGSTFKRPQGYFAAKLIEESGLKGINVGDAEVSQKHSGFIINKGNASAKDILNVINIVQDTVKSKFDVELHTEVLIIGEDKLN", "output": "Cell wall formation."}]}
+{"id": "function_test_1754", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNKDFNEFKKFIYNKKVAIIGLGISNMPLVEFLSNLGARVTGFDKKNENELENNINELKAKGVNFELGENYLDKLSNFDVVFRTPSMRTDHPILIKAKSEGAYITSEMEEFIKYCPAKLFCITGSDGKTTTTTLIYNILKTEGYTVWVGGNIGNPLFTKIEEIKKDDKVVLELSSFQLMSIKEPIEVALVTNVSPNHLDIHKDMEEYIKAKKNIFKYQRENDLLVINEDNKITKSMEEECRGRLLKFSMKEKLKEGSFYYNEDLYINEKKVCNVSEVKLKGMHNVENLLAAFSCVSEDSSIDSMREVAKNFNGVEHRLEFVKEIQEVKYFNDSIASSPTRTLAALQSFDRPVILIAGGYDKKISFEVLAKEGISHIKHLILLGDTKYKIEEAFKKVMRDSSEDLPISICNSIEEAINIAKENGESGDVVTLSPACASFDMFKNFEERGNKFKSIIRNL", "output": "Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)."}]}
+{"id": "function_test_1755", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTITSILQKMVKLKIITSSNFYLSTMLFNKNTLATFLSICVNHFTNHGHVCLPHVLIQHQKIFFTNHIALITKLWEIAKINTCGWIEQLLNSNTISNGSKNTPFIFYKNNFYINKFWLAEQKILKFISQKQNFKLINKNKIQKILKNIFNTNIDDTQKLAIILSIINNITFIIGGPGTGKTTIILKILLVLIRLHKKKINIKLTALTGKAANRLSESIHENIKKLNLTEHEKNIFNQKTTTLHNLLDLKPNKSFNYSCCKNKLYNLNLLIIDEASMIDITIMDKLISSIPKTTKIIFLGDYNQLPSISGGNILKNICSYYQEGFSTTTNKFLKQLFPNRITIKTIKKHQFSNINDKIIMLKKSYRFKKKSDIFKISEMLTKNKINNIKTLYQNINNDVNFKQISSKTNYNNIIFEITNSYSKYWSALKQSLPFLKIINIFNNYKILCILKNGLFGITELNLAIEKEMKKIGWIKKVTIINGQTWYFGKPILILKNNEEMNLFNGECGLTLLDANKKLKVFFLPKNQEQIYSIPIHLVPEHQTNWTMTVHKSQGSEFSEVVLILPTIMTSILTKELIYTAVTRSKKKLTIYSDENIFIKSLKKNIIRYSGLSIHQKIKF", "output": "A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD."}]}
+{"id": "function_test_1756", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSVQSAIRRKTAPDLRIRKNGEPIVMLTSYHAHTAALVDRHCDAILVGDSLGNVMHGFETTVPVTLEMMILQGCAVMRGSSQALVVVDMPFGSYEGSKEQAFQSAVRIMKETLCGAVKLEGGARMAETVAFLSERGIPVMGHIGLTPQSINTLGSFRAQGREEANWAPIENDARAIAEAGAFSIVIEAVAEPLARKITQSIAVPTIGIGASAACDGQILVLEDMLGLSPRSPKFVRRYGNLGPAIEEAIAGYARDVKSRAFPGPEHVYDMKKS", "output": "Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate."}]}
+{"id": "function_test_1757", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MVKNMDTIVQLAKHRGFVFPGSDIYGGLSNTWDYGPLGVELKNNIKKAWWQKFITQSPYNVGIDAAILMNPKTWEASGHLGNFNDPMIDNKDSKIRYRADKLIEDYMQNEKGDENFIADGLSFDEMKKIIDDEGIVCPVSKTANWTDIRQFNLMFKTFQGVTEDSTNELFLRPETAQGIFVNYKNVQRSMRKKLPFGIGQIGKSFRNEITPGNFIFRTREFEQMELEFFCKPGEEIEWQNYWKTFASEWLTDLNISEDNMRLRDHDEDELSHYSNATTDIEYKFPFGWGELWGIASRTDYDLRQHSEHSGEDFKYHDPETNEKYIPYCIEPSLGADRVTLAFLCDAYAEEGVEGSKDARTVMHFHPALAPYKAAVLPLSKKLSSEAIKIFEQLSSSFAIDFDESQSIGKRYRRQDEIGTPYCITFDFDSLEDNQVTVRDRDSMEQVRMPISELETFLAEKVKF", "output": "Catalyzes the attachment of glycine to tRNA(Gly)."}]}
+{"id": "function_test_1758", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAVIQITSDDTWQIQADGHPLRGTLQVPGDKSISHRALMLGAMAEGTTQITGLLVGEDTCSTASCFRALGAEISPLNATAVTVQGLGMGRLQEPGDVMNAGNSGTTMRLLLGVLAAQTGRFFTLTGDASLRSRPMARVVTPLLQMGAQIWGRQHHSRAPLAILGQPLEPITYYSPIASAQVKSALLLAALHTEGTTLIREPHRSRDHSERMLQAFGARLSVDEATCTVSLEGPAVLKGQKVIVPGDISSAAFWLVAASIIPDSELLLTNVGVNPTRTGILDVLWAMGAEITLENERLVTGEPVADLRVRSARLKSTRIGGELIPRLIDEIPILAVAAAFAEGVTEIRDAAELRVKESDRLKAVATELQKMGAKVTELSDGLDIQGGGPLQGTHLETYGDHRMAMSLAIAALNAKGTSEIHNASAAAVSYPEFVTVLQQIA", "output": "Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate."}]}
+{"id": "function_test_1759", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKIILATQNKRKLDEFIELSKNSNYPINFVIKPLKEDIGEIEENGNSYFENALIKANAVFNYYKEPVLSDDSGLELPEFKEILGIYSSRFAGINATDKENRYKLLDYLKSKNITETSAKYVCVLVYIFNQGEALSFKGEWEGKIIVSDNLNLDTGFGYDPMFVPKEYTITVSEMSISEKNLISHRAKAVNQFLNFLKDKK", "output": "Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions."}]}
+{"id": "function_test_1760", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAKLLVIKASMVDKSISFSEELTNRFVKYYLESNPNDEVITLDLNEVPMAQKTLNGSNLKNFFNQEDSDFYIDQLKSVHKVIFSCPMTNFNISATAKNYLDHVLVANKTFSYKYSKKGDAIGLLNHLSVQLLTTQGAPLGWYPWGNHTENLKGTFEFMGTKVVTPILVDGTKIPENANKTPVERINEFDSVIRLKAKEFAALPAVDWKPLEQ", "output": "Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.; "}]}
+{"id": "function_test_1761", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLDVNVFDELRIGLATADDIRRWSKGEVKKPETINYRTLKPEKDGLFCERIFGPTRDWECACGKYKRVRYKGIICERCGVEVTKSKVRRERMGHIELAAPVTHIWYFKGVPSRLGYLLDLAPKDLDLIIYFGANIITSVDEEARHSDQSTLEAEMLLEKKDVEADAESEIAERAEKLEEDLAELEAAGAKADARRKVQNAAEKEMQHIRERAEREIDRLEEIWQTFIKLAPKQMIRDEKLYDELVDRYEDYFTGGMGAESIQTLIRGFDLDAEAEELRTIINEGKGQKKMRALKRLKVVAAFQRSGNDPAGMVLNAIPVIPPELRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRMIELGAPEIIVNNEKRMLQESVDALFDNGRRGRPVTGPGNRPLKSLSDLLKGKQGRFRQNLLGKRVDYSGRSVIIVGPQLRLHECGLPKLMALELFKPFVMKRLVENEYAQNIKSAKRMVERQRPEVWDVLEEAISEHPVMLNRAPTLHRLGIQAFEPVLVEGKAIQLHPLACEAFNADFDGDQMAVHLPLSAEAQAEARILMLASNNILSPASGKPLAMPRLDMVTGLYYLTLKKSPEEFGGQGAYQPADENGPEKGVYSSYAEAIMAYDRGVLGLQAPVRIRLDHLRPPAELENELFPEGWNQGDTWLAETTLGRVMFNEILPWNYPYLEGIMVRKGGGADKIMLGDVVNDLAARYPMITVAQTMDKMKDAGFYWSTRSGVTIAMSDVLVLPNKDEILDRYEAAARQIETKYNRGKLTGRERYDRLVELWKDATDEVGQAVEDIYPDDNPIPMIVKSGAAGNMRQIWTLAGMKGMVVNSKGDYITRPIKTSFREGLTVLEYFNNSHGSRKGLADTALRTADSGYLTRRLVDVAQDVIVRVEDCGTRQGVRVPVAAEVLDATGAVSGYTRHDLIETSVSGRVLAGDATNAEGEVILAAGSDLTELNIDLLVEAGIQQVKVRSVLTCQTPTGVCAKCYGKSMASGKQVDIGEAVGIVAAQSIGEPGTQLTMRTFHQGGVGGDITGGLPRVQELFEARVPKNLAPIASADGVIHLEDEGNFYTLTLVPDDGSDNVVYDKLSKRQGLASIRVPMEHNPAAFIERTLAEGDHVTVGTRLLRGAAAPHDVLEVLGRRGVEQHLIDEVQAVYRAQGVAIHDKHIEIIIRQMLRRGTVIESGSTEFLPGSLVDLSEAKLANSEAIANGGQPAELRSEIMGITKASLATESWLSAASFQETTRVLTDAAINKRSDKLIGLKENVIIGKLIPAGTGISRYRNISIKPTEAARNAAYSIPTYGESIYGDDGFGEFTGASVPLDEAF", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_1762", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIGFKSFFMRTIIFQVLAILLLWGLLVAWVKYWYYPDMEKYFDNQQRIVAAGIANILDETGTDNIDYRGIIKTIEGMYIDSINNGMQDEIDYHPLFVVYDRDNRVLYSSQTQGEPLRLPPSVLSGSVNYAGANWHLAGSWKEKRQYRVIVGESFNDRTTLFGNPADVPLLGILAAIIVTLLFTAYFSLRPLRQIARTISDRQPGNLSPINVSEQYQEIRPVVMEVNKLMARIDAANQREKRFMADAAHELRTPIAAVLAQLHLLTQVTEQQERREIIGDMQQGLDRAASLSRQLINLAKLEAEDFPLKIEAVDIYAEIGKCIAQHVPYALEKDVELSLDGSEDVVVSTDRRALIAIFTNLLDNALKYAPPGSRIEANIRSLAPLGCYITLRDNGPGVSEEHRSRLFERFYRVPGTQQTGSGLGLAIARNLADKIGAQLRVTEGLDDRGIGFIIDLPESYRPQTESEPRP", "output": "Member of the two-component regulatory system RssA/RssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/RssB regulates cellular fatty acid composition, hemolysin production and cell surface topography. RssA/RssB negatively regulates the activity of SlhBA. It can also act as a negative regulator for the control of the swarming initiation."}]}
+{"id": "function_test_1763", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGCIKVISVFLAAVAAVDARAFFHNRGGNDVIPNSYIVVMKDGVTAEDFDSHISSVATTHSINKAKRGSETVGHKDSFNINGWRAYNGHFDEATIESILNDDKVDYVEHDRVVKLAALTTQPNAPTWGLGRVSHKAPGNKDFVYDSSAGQGVTIYGVDTGIDINHPEFRGRIRWGTNTVDNDNTDGNGHGTHTAGTFAGTTYGVAKKANIVAVKVLSAGGSGSTAGVIKGIDWCVTDAKAKGALGKAALNLSLGGAFSQANNDAVTRAQNAGIFVAVAAGNDNKDAKNSSPASAPAVCTAASSTIDDQKSSFSNWGTIVDIYAPGSNILSAAPGGGTRTLSGTSMASPHVCGVGAAMLAQGVSVAQACDRIKQIANAVIKNPGTGTTNKLLYNGSGR", "output": "Secreted subtilisin-like serine protease with keratinolytic activity that contributes to pathogenicity."}]}
+{"id": "function_test_1764", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MCGIVGYIGDKQATPILLEGLTRLEYRGYDSAGIAILHNGNINIKKAKGRLNVLRELVEKDYMEGTIGIGHTRWATHGEPSDTNSHPHLSQSGLIAVVHNGIIENYLPLKKWLIEEGYNFISETDTEVVANLLEYYYNGDIVEALRKVLDRIEGSYALGVLCKDNPDMIVAARKEAPLIVGIGNGENFIASDIPAILKYTRNVYFLDDHEIAIIKKDSVEFIDVFGRKIGKSLFEVKWDVEAAEKGGYEHFMIKEIHEQPAAIKDTLRGRIINDSQIVLDNINITKEDLEKIEKIFIVACGTAYHAGVVGKYVIESFARIPVEVDVASEFRYRNPIVNERILTIVISQSGETADTIAALKEAKRKGSRVIAITNVVGSSVSREADEVLYTWAGPEIAVASTKAYTTQLIALYLIALDFALKKGTMSSTKVVEIISELKKLPDKVQYLLDNKEVIQKFASEHYNVKDVFYIGRGLDYAVAMEGSLKLKEISYIHSEAYPAGELKHGTLALVEEGTLIIALATQDDLFEKMLSNIKEVKARGGYVVAFAKQGNLQLEGVVDKVIYIPDTLKELTPVLTVVPLQLLAYYMAVEKGCDVDKPRNLAKSVTVE", "output": "Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source."}]}
+{"id": "function_test_1765", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSEDDPRPLHIRRQGLDPADELLAAGALTRVTIGSGADAETHWMATAHAVVRQVMGDHQQFSTRRRWDPRDEIGGKGIFRPRELVGNLMDYDPPEHTRLRRKLTPGFTLRKMQRMAPYIEQIVNDRLDEMERAGSPADLIAFVADKVPGAVLCELVGVPRDDRDMFMKLCHGHLDASLSQKRRAALGDKFSRYLLAMIARERKEPGEGMIGAVVAEYGDDATDEELRGFCVQVMLAGDDNISGMIGLGVLAMLRHPEQIDAFRGDEQSAQRAVDELIRYLTVPYSPTPRIAREDLTLAGQEIKKGDSVICSLPAANRDPALAPDVDRLDVTREPIPHVAFGHGVHHCLGAALARLELRTVFTELWRRFPALRLADPAQDTEFRLTTPAYGLTELMVAW", "output": "Involved in the coupling of aromatic side chains of the heptapeptide of vancomycin."}]}
+{"id": "function_test_1766", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNQSYGRLVSRAAIAATAMASALLLIKIFAWWYTGSVSILAALVDSLVDIAASLTNLLVVRYSLQPADEEHTFGHGKAESLAALAQSMFISGSALFLFLTGIQHLVRPEPLQAAGVGVVVTLIALVSTLALVTFQRWVVRKTQSQAVRADMLHYQSDVMMNGAILVALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDEERQDIITIVTAWPGIRGAHDLRTRQSGPTRFIQIHLEMEDNLPLVQAHVIADQVEQAILRRFPGSDVIIHQDPSSVVPAAQQGFFER", "output": "Divalent metal cation transporter which exports Zn(2+), Cd(2+) and possibly Fe(2+). May be involved in zinc and iron detoxification by efflux."}]}
+{"id": "function_test_1767", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAERLDPDVVLNHVLVPKHEVIDDEEEIEKILEELGVEKDDLPRIHTNDPVVVALSEKLGKRIKPGSLVKIVRDSPTAGKTVVYRVVTNPPE", "output": "DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_1768", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGRMHSPTFDGRHTRFVLTAFFVRQIMALAGFALLATIALGIAALATWNVADPSLSYATGNQPTNLLGYSGAIFADIVMQFLGLSAIIAFLPIIAWAIALIAGRKFNRIPARLVAWVAGAIVCAASLGCFPAPVTWPLPNGIGGVIGDMILRFPALFIGAYPTGTIATILGVIFAAPAAWLMLFAAGIVGGLDDELEREEAVPVATSKARAAREAEEDDEDDGEGFFANMLAFGAIAHYWYITQARLRRLFGLKSKSLHTEFEHPYDFNEYEFGTLNEPSRLKTAINRLDQRSEPSFEERAASRRQMSPPSIALDHDNNADDEPPFDADGRRLPNGILSDDESDDKFTPRQAPGRGQPRITAPSARPKPSERVAREAQASFIAADGFQLPTVHLLAEPKNVVRDNTLSEEVLEQNARLLEGVLEDFGVKGEIIHVRPGPVVTLYELEPAPGIKSSRVIGLADDIARSMSAIAARVAVVPGRNAIGIELPNQTRETVFLRELVGSRDFENSKAKLAMALGKTIGGEPVIADLAKMPHLLVAGTTGSGKSVAINTMILSLIYRMSPEQCRLIMIDPKMLELSIYDGIPHLLSPVVTDPKKAVVALKWTVREMEERYKKMSKIGVRNIDGFNSRVQQALDKGEILTRTVQTGFDRQTGEAMYETEEFDLKPLPYIVVIIDEMADLMMVAGKDIEGAVQRLAQMARAAGIHVIMATQRPSVDVITGTIKANFPTRISFQVTSKIDSRTILGEQGAEQLLGMGDMLYMAGGGRIQRVHGPFVSDNEVEEIVAYLKTQGSPEYLEAITEEEDEDGAGSGPAGAGNFSDSEDPYDQAVAVVLRDGKASTSYVQRRLGIGYNRAASLIERMEQEGIIGPANHAGKREILVPTEADIIER", "output": "Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif (By similarity)."}]}
+{"id": "function_test_1769", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MALDDISAVPKGALDTDPAVERPPPLLDADRSDSERLQPGVKRAEMLRKGWTRQGLIIAFTGLFLATLSINFGDYSTQVYVPYATSAFKQHSAMSAARVVGNITRIAAYPIIAKLGDVFGRAEMFILSIVFQAVGYAIYAGCKNVGQYIAGGIFEAIGSTGFGLTQQVFVADVTNLINRAVWSTLPDSLTVIPALYLGTEIAEAVLEKNEWRWGFGMWAIIEPVCSVLLVGTMLYYQKRARKDPSPAEFASEPTERNVDDGWWKRIYNLVWVQLDAFGAILLLLGLSLFLVPLSLTGSGNSDDWHRGSFIAMLVLGVVIFVAFLAWDTWCAKKPFIPYRMIKNRTVAAACLLGILDFFHYSVFSVFFTSYLQVAAHHGAGPATRIDNSLRVAFQVAGIFAAYFMKFTKRSQVWVFTGVPLCVLGMGVLLYLVDMGEGRVGNEAAFVTAKSLIGIGRGFYQTASQVSVQAKVSRGEVSVVTAVFFAAMSIGGAIGTSVAGAIWRSTLPPKLAQHLPAELKDQAQAIFGSIVVAQKYEVGTPARDAIDMCYRQSQRMLAIAALAALAPMLIIMFFLENVPLTDETTLIELHGNREAVKKNHSGGEGKEARS", "output": "Involved in the transport of siderophore enterobactin and so has a role in iron homeostasis."}]}
+{"id": "function_test_1770", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKRNVLLLPLLIFLLIAAALLWQLARNAQGDDPTNLESALTGKPVPAFRLESLETPGQYYQAEVLTQGKPVLLNVWATWCPTCRAEHQYLNRLAAQGIRVVGLNYKDDRAKAVAWLKELGNPYALSLSDSDGMLGLDLGVYGAPETFLIDGRGIIRYRHAGDLNARVWESELKPLWDRYSREAAQ", "output": "Involved in disulfide bond formation. Catalyzes a late, reductive step in the assembly of periplasmic c-type cytochromes, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible subunit of a heme lyase (By similarity)."}]}
+{"id": "function_test_1771", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSVSSRPGRRRFALIPSAGTGTRAGGDLPKQYQPLAGRPMLWHTVQAFLASAAIDRVVVVTSPGAPALAARFPGLGFDAARLVEVDCGGDSRHASVTNGLAALRGLGAHEDDWVLVHDAARPGLTPALIARLVGAVEADGGQAVGGILALPVADTLKRADAGQHIAETVPRGGLWQAQTPQMFPLGLLQRALSEALTAQRIVTDEASAIEAAGHRPLLVAGALRNFKVTYPDDFALAEAILAGAAPTQEDSQA", "output": "Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP)."}]}
+{"id": "function_test_1772", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAKNRHLFTSESVSDGHPDKIADQISDAILDAIISKDPDARVACETTVTTGLVLVAGEITTSVYVDIPKIVRDTIKEIGYTRAKYGFDAETCAVLTAIDEQSPDIAQGVDEALESRSGNEIDAAIEAIGAGDQGLMFGFATDETEELMPLPIFLAHGLARKLTELRKTNKLDYLRPDAKTQVTVEYDEFNQPVRIDTIVVSTQHHPDITQEQIAKDLHTYLFPEVIDASFLDEDTKYFINPTGRFVIGGPLGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSGAYAARYVAKNIVAAGLAKKVEVQVAYAIGVARPVSISIDTYGTSDYSEQELIDGVNALFDLRPAGIIHMLDLRRPIYRQTAAFGHFGRSDLDLPWERTDKAEALKKLIVK", "output": "Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme."}]}
+{"id": "function_test_1773", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTKAPVAPVVLVILDGWGYCEETRGNAIAAAKTPVMESLWTAYPHTLIHTSGKAVGLPEGQMGNSEVGHLNIGAGRVVPQELVRISDAVEDGSILSNSALVKICQEVRNRNGKLHLVGLCSEGGVHSHITHLFGLLDLAKEQRISEVCIHAITDGRDTAPTDGINAISALEDYINHVGIGRIVTVSGRYYAMDRDRRWDRVQRAYDVMTQDGVGDGRKAVDVLQASYAEGVNDEFIVPVRIAPGTVEPGDGVIFFNFRPDRSRQLTQAFVSPEFTGFARQQIKPLSFVTFTQYDSDLSVSVAFEPQNLTNILGEVIANQGLNQFRTAETEKYAHVTYFFNGGLEEPFAGEDRELVSSPMVATYDKAPAMSATAVTDTAIAAIQKGIYSLIVINYANPDMVGHTGQIEPTIKAIETVDRCLGRLLEGVSKAGGTTIITADHGNAEYMLDEAGNSWTAHTTNPVPLILVEGEKVKIPGYGTNVELRSDGKLADIAPTILDILQLPQPPEMTGRSLLQPAEYEVELSRTPIPVGLN", "output": "Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate."}]}
+{"id": "function_test_1774", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNDIENLDRPPAIFIMGPTASGKTALSIALRQRLPVELVSVDSALIYRGMDIGTAKPSAQELALAPHRLIDIRDPAESYSAADFRKDALKEMADITAAGRIPLLVGGTMLYFKALLDGLSPLPSADPQVRQRIEQQASELGWGALHQQLAVIDPVAAARIHPNDPQRLSRALEVFFISGKTLTELTKISGETLPYRVHQFAIAPASRELLHQRIELRFHQMLDAGFEAEARVLFDRGDLHTDLPAIRCVGYRQMWSYLSGEIDYNDMVYRGVCATRQLAKRQMTWLRGWSSVQWLDSDKPGEALDSVIQVVSA", "output": "Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)."}]}
+{"id": "function_test_1775", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MITKAIYPGTFDPITNGHLDLVTRASAMFSHVILAIADSSSKKPMFTLDERVALAKKVTAPLKNVEVLGFSELMAEFAKKHNANILVRGLRSVSDFEYEWQLANMNRHLMPKLESVFLIPSEKWSFISSSLVKEVARHGGDITPFLPKPVTKALLAKLA", "output": "Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate."}]}
+{"id": "function_test_1776", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQKRAIYPGTFDPITNGHLDIVTRATQMFDHVILAIAASPSKKPMFTLDERVALAQKATAHLGNVEVVGFSDLMANFARDRQANILIRGLRAVADFEYEMQLAHMNRHLMPQLESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPDNVHQALMDKLK", "output": "Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate."}]}
+{"id": "function_test_1777", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "METYAVFGNPIAHSKSPFIHQQFAQQLDIVHPYGRVLAPINNFINTLDAFFAAGGKGANITVPFKEEAFARSDELTERASLAGAVNTLKRLEDGRLLGDNTDGIGLLGDLERLNFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTASRAEALAKIFAHTGSVHATDMDKLDGCEFDLIINATSSGIRGEIPAIPASLIHPSLCCYDMFYQKGNTPFLSWCVQQGAKRYADGLGMLVGQAAHAVLLWHGVLPQVEPVIEQLQQELLA", "output": "Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)."}]}
+{"id": "function_test_1778", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTDSIMQNYNQLREQVINGDRRFQHKDGHLCFEGVDLDALARQYPTPFYVFSEPEIIRNIHEIQQAFAAHKNTKTFFASKTCSVMGVLKAIRDAGICAEANSQYEVRKCLEIGFRGDQIVFNGVVKKPADLEYAIANDLYLINVDSLYELEHIDAISRKLKKVANVCVRVEPNVPSATHAELVTAFHAKSGLDLEQAEETCRRILAMPYVHLRGLHMHVGDQVPESEPFAKATKVLVDESRRLEEVLGIKFDLINVGGGIPVPYKYDDENGDPLKDNMYAGITAQDFADAVIREVHKWRTDVEICIEPGRKVTGSAAVLLTEVSCEKRKTNYDLNGNVECHVEWKFVDAGYSVLSDSQHFDWFFYVYNASRMTAAHDAWIKLAGPLCDGGDYFHMGVKGEEFLLPKETHVGDIVAFLDAGAYTIESQTVYNNRPRTGVVMIDKNGDTRLIRREDSYEDMVKYDIY", "output": "Catalyzes the decarboxylation of D-ornithine and D-lysine . Ornithine is likely the physiological substrate . Has no detectable diaminopimelate decarboxylase activity in vitro ."}]}
+{"id": "function_test_1779", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKIAIGCDEMGYELKQTLITRLKEKNIEFTDFGSFENEKVLYPSIAEKVALEVKNNDYDRGILICGTGIGMAITANKIHGIRAAQIHDSYSAERARKSNDAHIMTMGALVIGPSLAVSLLDTWLDSDFSGGRSQAKVDLMEEIDQKNR", "output": "Catalyzes the interconversion of ribulose-5-P and ribose-5-P."}]}
+{"id": "function_test_1780", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSAKPIYKRVLLKASGEALMGSQGFGIDVAVADRIASDIAEARAMGVEVGVVVGGGNIFRGVAVASKGGDRVTGDHMGMLATVINALALATSLRKLDIDTVVLSAIAMPEICESFSQRATLYHLSLGRVVIFAGGTGNPFFTTDSAAALRAAEMGAEAIFKGTQVDGIYSADPKKDPSATRFDRLTHSEILEKGLAVMDVAAVALARENAIPIVVFSIHEKGGFTEILTGGGRATIVTDN", "output": "Catalyzes the reversible phosphorylation of UMP to UDP."}]}
+{"id": "function_test_1781", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLKLLIPTIMLFPMIWTLNPKWLWSATTTHSLIIASLSLTLFKCYSTTQWSNLNYMLATDMISTPLIILTCWLLPLMIIASQNHMSTEPINRQRSYITLLVSLQALLIMAFSATEIILFYIMFESTLIPTLIIITRWGNQTERLNAGIYFLFYTLAGSLPLLVALLYLYNTAGSLSFISMNLISIPPNTWTNTFLWVACVTAFLVKMPLYGVHLWLPKAHVEAPVAGSMILAAILLKLGGYGMIRMTIMLEPATKSLAYPFIILALWGIIMTGSICMRQSDMKSLIAYSSVSHMGLVASGILIQTTWGFTGAIILMIAHGLTSSALFCLANTAYERTHSRTLLLARGMQIILPLMATWWFIMSLANMALPPLPNLMGELMILVSMFNWSNWTILLTGTGTLITASYSLYLYMSSQRGPTPNNLTFMELSHTREHLLLTLHIIPIILLMIKPELIWGWCW", "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)."}]}
+{"id": "function_test_1782", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAKFNVLDHNLVPEHHIVSEEEEKTILKELGIEKEFLPRISPNDPVIKALEAIHGKIKDGTVIKIIRNSPTMGHSVYYRVVASEVFK", "output": "DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_1783", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKPPIIIINFKAYENSFGDKAVNLGKKIEKISKEYSVEIILSTPATMIYRMSQEVDLPIYAEHVDPVPLGAFTGAILPEMVKDAGAKGTLINHSERRLRADEIDDVLKRTKKLGLKSILCVDRYELVYPFSLLKPDAILIEPPELIGTGVSVSKAKPEVITRAVDEIRKSEGIYLIAGAGITTGEDVYKALKLGAHGIGVASAVMKAKEPEKVVEDFITSALRAISS", "output": "Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)."}]}
+{"id": "function_test_1784", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSQLKSSAIMDARILWPAFGGAFRKLDPRTLARNPVMFVVAIVSALTSVLFLRDLITGGGDLRFTLQIIIWLWFTVLFANFAEAVAEGRGKAQADSLRKARTETQAKLLAGEDRSKFKLVPGTSLKVGDIVLVEAGDIIPSDGEVVEGVASVNEAAITGESAPVIRESGGDRSAVTGGTQVLSDWIRVRITAAAGHTFLDRMISLVEGAERQKTPNEIALNILLVGMTLIFVLATATIPSFASYSGGYISVTVLVALFVTLIPTTIGALLSAIGIAGMDRLVRFNVLAMSGRAVEAAGDVDTLLLDKTGTITLGNRQATDFRPVKGVTEQELADAAQLASLADETPEGRSIVVLAKEKYGIRARDMATLHATFVPFTAQTRMSGVDIDGSSVRKGAVDSVLAHVNQSTVASHATRPNSDTIRDLQAIADEVAKSGGTPLAVERDGRLLGVVHLKDIVKGGIRERFAELRKMGIRTVMITGDNPMTAAAIAAEAGVDDFLAQATPEDKLKLIRDEQAKGKLVAMCGDGTNDAPALAQADVGVAMNTGTVAAREAGNMVDLDSDPTKLIEIVEIGKALLMTRGSLTTFSIANDVAKYFAIIPAMFAVFYVAPGQSTGPLQALNIMHLATPQSAILSAIIFNALIIIALIPLSLRGVKYRAIGAGALLSRNLLVYGLGGIIVPFVGIKIIDMAVTALGLA", "output": "Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm."}]}
+{"id": "function_test_1785", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNIDLYSDRAKQAVQSAQSLALARGHQQFAPEHILKVLLEEKDGLSRALIQSAGGRPDQLDGGVETLLAKTPRVDGAGGQLYMKPDTARVFAEAEKSAKAAGDAFVTTERLLIAIAKEGGEAAKLFKEAGVSAQSLETAANAMRKGRTADSANAEEGYEALKRYARDLTAAARDGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLALRIVNGDVPESLKDKKLLSLDMGSLIAGAKYRGEFEERLKAVLGEVTAAEGSIILFIDEMHTLVGAGKGDGAMDASNLLKPALARGELHCVGATTLDEYRKHVEKDAALARRFQPVFVSEPTVEDTVSILRGLKEKYEVHHGVRISDSAIVAAATLSNRYIADRFLPDKAIDLVDEASSRVRMQIDSKPEELDEIDRRLVQLKIEREALSKETDAASKQRLENLEVEIDDLQFRSDEMTARWKAEKEKVGGAAQAREALDRLRADLANAQRAGDFARAGQIQYGEIPALERRLAEAEAGDTQALTPEVVDAEQIAAVVSRWTGVPVEKMLEGEREKLLKMEDELRGRVVGQDEALEAVSDAVRRARAGLQDPSKPIGSFLFLGPTGVGKTELTKSLAEFLFADEAAITRMDMSEYMEKHSVSRLIGAPPGYVGYDEGGALTEAIRRRPYQVVLFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTLIIMTSNLGAEYLASQEDGEDVEAVRPMVMNTVRGHFRPEFLNRIDEIILFKRLSRHNMGDIVRIQLQRVEKLLADRRMALALDAEALNWLADKGYDPVYGARPLKRVIQKELVDPIAKKLLAGEIEDGGVIAVGVTDGQLSFGKAVLQ", "output": "Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK (By similarity)."}]}
+{"id": "function_test_1786", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MMTIRNSHPLIKIVNNSLVDLPAPINISTWWNFGSLLGLCLITQIMTGLFLAMHYTSDIASAFNSIVHIMRDVNNGWLIRIIHANGASLFFICLYLHTGRNIYYNSFNQISTWTMGVILMFLVMGTAFMGYVLPWGQMSFWGATVITNLLSAIPYLGNFLVQWVWGGFAVSNPTLTRFFMIHFLLPFLIIGGLLVHLLFLHQTGSNNPLGLNSNQDKIPFHPLFSYKDLVGVLIIMSGLLLLSLLSPFLLGDAENFYPANPLVTPVHIQPEWYFLFAYAILRSIPNKLGGVIALVLSVSILFILPLSSKFKMQGNQFYPFNQIMFWVFINLVIMLTWIGARPVEEPFIIMGQTLTCSYFMYFILNPMISYLWDYNLN", "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."}]}
+{"id": "function_test_1787", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSSYSELSNLPIREIPGDYGFPIISAIKDRYDYFYNQGEDAWFHNKAEKYKSTVVKINMAPGPFTSNDYKLVAFLDANSFVCMFDNSLIDKTDTLGGTFKPGKEYYGGYRPVAFIDTKDPNHAALKGYILSSFAKRHNLFIPLFRNTLSDHLFNNLEKQVTEQGKADFNALLPTMTFDFIFRLLCDQKNPSDTVLGAQGPEHLRKWLFPQLIPSLSAKKLPNIIEDMLFHNFLIPFGFIKSDYNKLVDAFSKSAVSMLDEAEKLGIKREEAVQNILFLVGINMFAGLNAFFPHLFRFVGEAGASLHTQLAKEIRSVIKEEGGAITLSAINKMSLVKSVVYETLRLRPPVPLQYGKAKKEFMVQSHDASYKINKGQFVVGYQPMASRDPKIFANPDEFVPDRFMNDGEKMLKHVLWSNGRETESPAPDNKQCPGKDLVHLLGRLILVEFFIRYDTFTLEITPLFRAPNVAFNTLTKASK", "output": "Involved in the biosynthesis of the anti-fungal toxins colneleic acid and colnelenic acid. Can use (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoic acid (9-HPOD) and (10E,12Z,15Z)-(9S)-9-hydroperoxyoctadeca-10,12,15-trienoic acid (9-HPOT) as substrates but has a very low activity with the corresponding 13-hydroperoxides."}]}
+{"id": "function_test_1788", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQYKLTRIDPDAANDQYPIGERETVADPLVEGQVHKNIFMGKLEDVLNSTVNWGRKNSLWPYNFGLSCCYVEMTTAFTAPHDIARFGAEVIRASPRQADFMVIAGTCFIKMAPVIQRLYEQMLEPKWVISMGSCANSGGMYDIYSVVQGVDKFLPVDVYIPGCPPRPEAFLQGLMLLQESIGQERRPLSWVVGDQGVYRAEMPAQKDLKREQRIQVTNLRSPDEV", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_1789", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "FPYQGSSIMLESGKVNDYEVVYPRKVTALPKGAVQQKYEDTMQYEFKVNGEPVVLHLEKNKGLFSKDYSEIHYSPDGRRITTHPLVEGHCYYRGHIRNDADSTASISACNGLKGHFKIQGETYFIESLKLSDSEAHAVFKYENVEKEDEAHKMCGVTQNWESYEPIKKASQLIVSTEFQRYMEIVIVVDHSMYTKYKGDSDKIKAWVYEMINTISESYRYLYIDIIVSALEMWSEKDLINVETSAENTLKSFGEWRAKDLIHRISHDNAQLLTATDFDGPTIGLAYVASMCDPKRSVGVVQDHSSVNHLVAITLAHEIAHNLGVHHDEGSCSCGSGYTCIMSPVINSEVIKYFLDSK", "output": "Snake venom metalloproteinase that impairs hemostasis in the envenomed animal."}]}
+{"id": "function_test_1790", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQNTSFDNESDYSDDSDFASASETENRIGLTVPLELAGGRLDAVLAKLLPDYSRSRLTSWIKEGAVIVNDKPSQPKDKMIGGEQICVTVRPSEENLAFVPEPMALDIVYEDDTVIVVNKPAGLVVHPAAGNWTGTLLNGLLAHCPELSQVPRAGIVHRLDKETSGLMVVAKTLPAQNSLVRQLQERTVKRIYRAVANGIVPFDGKIETQIGRDPHNRLKMAVVKFGGKPAVTHVKVLERYLTHSYIECSLETGRTHQIRVHMREANHPLAADPVYGNPRHPCGDTVKEAVKSLGARQALHAYRLSFTHPESGETVSFEAPIPNDIYHLLSVLRLEAGLDSSLSNEEEWQDKFGADDDDDWNEDDYDVEVVYVRE", "output": "Responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA."}]}
+{"id": "function_test_1791", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTPAEIAPKDRLIVALDLPSVDAAEAMIARLGDSVTFYKIGYRLAYAGGLPLVARLADKGKKVFLDLKLHDIGNTVAQGVESITRLGATFLTVHAYPQTMKGAVEGRGGSNLKILAVTVLTSYNEDDLHAAGFRLGVAELVEARAQQAQVLGIDGLVSSPEEVGALRKIVGHQMSLVTPGIRPAGSASGDQKRIMTPGRAITAGADYLVVGRPVVEAAEPKAIADAIQAEIGQALGA", "output": "Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP)."}]}
+{"id": "function_test_1792", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "LLMTGVESGRDAYIAKNYNCVYHCFRDDYCNGLCTENGADSGYCYLAGKYGNACWCINLPDDKPIRIPGKCHRR", "output": "Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission."}]}
+{"id": "function_test_1793", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSFFVQKLSEKATIPTKGSANSAGYDLYAAAECIVPRRGKVLVDTDLAIAVPEGTYGRVAPRSGLASKHSIDTGAGVIDADYRGHVRVLLFNYSDVDFPIKVGDRIAQLILERIVNPPVILVESLEATVRGANGFGSTGV", "output": "This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA."}]}
+{"id": "function_test_1794", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRGEREFRKVRAHGAAVRDPLFTLRLTDYRPRYGERWHPRAIIGLVVSKKTLKHAVKRNRARRRVREALRTMPPELLPGGLPACRAILMLNPGVLTVPFPELQAALAQALQRGAGATKRGGAKGKGGKKGGGQVAGERAGNESGSGRVSAEVNPTSASPASPAEKS", "output": "RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme."}]}
+{"id": "function_test_1795", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTNTRKTHPLIKIINHSFIDLPAPSNISAWWNFGSLLGLCLTIQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYMHANGASMFFICLFLHVGRGLYYGSYTYFETWNIGVILLFATMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALVXVHLLFLHETGSNNPSGLVSDSDKIPFHPYYTIKDALGILLLIMALMTLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVFSILILTLFPLLHLSKQRSMMFRPLSQCIFWILVADLFTLTWIGGQPVEYPFIIIGQLASILYFSIILLILPTASLIENKLLKW", "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."}]}
+{"id": "function_test_1796", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKRIPRKTRGKSSGKGNDSTERADDGSAQLRDKQSSKVTQNVKEPGTTLKEQYKTRPSLQTVQKATENAELPMQTNDEGAVDKKGNTKGDKTNEHVEAEVNAADATKRQAKDTDKQKAQVTYNDTGINNANELSRSGNVDNEGGDNQKPMTTRIAEATSAIISKHPARVGLPPTASSGHGYQCHVCSAVLFSPLDLDAHVASHGLHGNMTLTSSEIQRHITEFISSWQNHPIVQVSADVENKKTAQLLHADTPRLVTWDAGLCTSFKIVPIVPAQVPQDVLAYTFFTSSYAIQSPFPEAAVSRIVVHTRWASNVDFDRDSSVIMAPPTENNIHLFKQLLNNETLSVRGANPLMFRANVLHMLLEFVLDNLYINKHTGFSQDHTPFTEGANLRSLPGPDAEKWYAIMYPTRMGTPNVSKICNFVASCVRNRVGRFDRAQMMNGAMSEWVDVFETSDALTVSIRGRWMARLARMNINPTEIEWALTECAHGYVTVTSPYAPSVNRLMPYRVSNAERQISQIIRIMNIGNNATVIQPVLQDISVLLQRISPLQIDPTIISNTMSTVSESTTQTLSPASSILGKLRPSNSDFSSFRVALAGWLYNGVVTTVIDDSSYPKDGGSVTSLENLWDFFILALALPLTTDPCAPVKAFMTLANMMVGFETIPMDNQIYTQSRRASAFSTPHTWPRCFMNIQLISPIDAPILRQWAEIIHRYWPNPSQIRFGAPNVFGSANLFTPPEVLLLPIDHQPANVTTPTLDFTNELTNWRARVCELMKNLVDNQRYQPGWTQSLVSSMRGTLDKLKLIKSMTPMYLQQLAPVELAVIAPMLPFPPFQVPYVRLDRDRVPTMVGVTRQSRDTITQPALSLSTTNTTVGVPLALDARAITVALLSGKYPSDLVTNVWYADAIYPMYADTEVFSNLQRDMITCEAVQTLITLVAQISETQYPVDRYLDWIPSLRASAATAATFAEWVNTSMKTAFDLSDMLLEPLLSGDPRMSQLAIQYQQYNGRTFNVIPEMPGSVVTDCVQLTAEVFNHEYNLFGIARGDIIIGRVQSTHLWSPLAPPPDLVFDRDTPGVHVFGRDCRISFGMNGAAPMIRDETGMMVPFEGNWIFPLALWQMNTRYFNQQFDAWIKTGELRIRIEMGAYPYMLHYYDPRQYANAWNLTSAWLEEISPTSIPSVPFMVPISSDHDISSAPAVQYIISTEYNDRSLFCTNSSSPQTIAGPDKHIPVERYNILTNPDAPPTQIQLPEVVDLYNVVTRYAYETPPITAVVMGVP", "output": "Inner capsid (core) component. Displays NTPase, RNA 5'-triphosphatase (RTPase) and RNA helicase activities and probably participates in transcription of the viral genome. Helicase activity might be involved in unwinding or reannealing dsRNA during RNA synthesis. RTPase enzymatic activity represents the first step in RNA capping, which yields a 5'-diphosphorylated plus-strand RNA (By similarity)."}]}
+{"id": "function_test_1797", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTNVVQETIGGLNSPRTCPPCILVIFGATGDLTARKLLPALYHLTKEGRLSDQFVCVGFARREKSNELFRQEMKQAVIQFSPSELDIKVWEDFQQRLFYHRSEFDNNMGYTSLKDSLEDLDKTYGTRGNRLFYLSTPPQYFSRIIENLNKHKLFYKNQDQGKPWSRVIIEKPFGRDLDSAKQLQQCINENLNENSVYHIDHYLGKETVQNILTTRFANTIFESCWNSQYIDHVQISLSETIGIGSRGNFFEKSGMLRDMVQNHMMQLLCLLTMEPPTTFDADEIRKEKIKILQRISPFSEGSSIVRGQYGPGTVQGVSVLGYREEENVDKDSRVETYVALKTVINNPRWLGVPFYLRAGKRLAKKSTDISIIFKKSPYNLFAAEECSRCPIENDLLIIRIQPDEGVALKFNCKVPGTNNIVRPVKMDFRYDSYFQTTTPEAYERLLCDCIIGDRTLFTGGDEVMASWKLFTPVLEEWDQDSSPSFPNYPAGSSGPKEADALIERDGRSWRPL", "output": "Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone."}]}
+{"id": "function_test_1798", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDMLSLNQLQLNIEKRNLFDLCITFLPSAITYIKGANGSGKSSLLRMIAGIMQPSSGNIYYKNSHINNCIKPYCTYIGHNLGLKLEMTVFENLKFWSEIYNSTETVPAAIHYFKLDYLLDEKCYNLSSGIQKIVAIARLIVCQSDLWLLDEVESNLSKENKDLLNNLIVMKANSGGIILLSSHQENVIKSAQILQLK", "output": "Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system."}]}
+{"id": "function_test_1799", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEVICKHYTPLDIASQAIRTCWQSFEYSDDGGCKDRDLIHRVGNIFRHSSTLEHLYYNFEIKGLSRGALQELSRHRIASLSVKSSRYTLRELKEVESFLPLNETNLERAKEFLVFVDDEKVNEMSVLALENLRVLLSEHNIKNDLAKYAMPESYKTHLAYSINARSLQNLLTLRSSNKALKEMQDLAKALFDALPYEHQYLFEDCLKH", "output": "Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant."}]}
+{"id": "function_test_1800", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSGNKFDQEKVDLHVLDPFFIEGTARVAQFGEQKYGRSNWMQGLTQTRIINAIKRHIAQIEKGEDIDEESGFHHAYHAAWGCQVLAYQHRNGQTHLDDRRWSESVRDADTKIGTCEGISGHTVPCMYEGPFGRLHPVDGEKDGLVMSFVQSEADEGTAQGDPIQQLQQMISEWADQVYPDRTVENALTKMMLHEIPELLHGKAMDPAEFADVAILLFDVAHLQGIDIAQAMREKMEINQARDWKIDPATGLMSHVKPKGMMETIRDAVQGIGDAARIMAAPSRLLNGNNMELAEYTAETLPKPPEKPWEITIPNWALKTEEGTHIKLRAGSGVFGRVKYQSQCILMHKNMRKRSHLETYYCATIKDTVTEDEYNVPWSEIEPWTN", "output": "Catalyzes the hydrolysis of dGTP into dGMP, which is needed among other for the first step of biosynthesis of dZTP (2-amino-2'-deoxyadenosine-5'-triphosphate)."}]}
+{"id": "function_test_1801", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQSHIGQWTSTAKGHLSRDENGDEKTDYSRWRLVDRQGRQTWRYLESDEENEKSPQTVPEKYFLGLDTGLPDLPKAETPLQAAQDGVSFLSQLQLSSGQWASECTGPMFILPCVIIAWYVTNTPIPPAYAIEIRRYLFARQRVEDGGWGWHVEARSSAIGTALNYVVLRLLGASKDDHRLIQARKLLHSYGGATYAPGIAKFWLCVLGVMKWECVNPFLPEFWLLPDSDPTAPSKWYIHTRTNFTSLSYIWSKQWSFAGDEVTKQLQTELYPEPYSAIDFAAHRTSLAEVDNNYPKWWLVNLMNWLTVAVYIPYMRKKATVESAEQRVWELIQAEDKNSEFIGLSPISKAANMIACYIHDGKDSESVRSHGETIFQYFWMNGEGMACNLSDGIQVWDTSLAVQAIAAAGGAGNPRFQSTVIKAHEFLEDHQLLDDVQDQEMCCRGHRKGGWPFSTKYQGYMISECTGEGLRSILQLQKTFQLDLKKRIPADRLHNAVDCLLNLQNDTGGFGVYEKRQGSLKLAWLEMGEFSGKTMVTYDYVECTTAVVSALASFSEFYPDYRKEEVQTARTRGLEFIKSSQKPYGGWHGAWGVCFTYAGMFALESLALAGETYSNSEPSRKGCTFLVSKQRDDGGWGESYLSFQKEEYIEHEDAQVVQTAWACLGLMHAEYPDKTPVKRGLKLIMSRQQSKGHWLQEQYEGGVGDGVISYSNYKLYWPVRALAEYVRRFGNEEM", "output": "Terpene cyclase/mutase; part of the gene cluster that mediates the biosynthesis of the meroterpenoids nectripenoids A and B, as well as cochliquninone D and isocochliquninone E . The pathway probably begins with the HR-PKS ntnH that catalyzes two chain-extension steps to form a reduced triketide, which then primes the SAT domain in the NR-PKS ntnG to initiate three more cycles of extension to give a linear hexaketide corresponding to the polyketide part of nectripenoids (Probable). The FAD-dependent monooxygenase ntnJ then performs an oxidative decarboxylation at C11 of the ntnH/ntnG product, via an electrophilic aromatic hydroxylation with concomitant ipso-decarboxylation (Probable). The membrane-bound polyprenyl transferase ntnF then introduces a farnesyl group before the FAD-dependent monooxygenase ntnK functions as the first epoxidase on terminal C12'-C13' olefin, followed by a second epoxidation on C7'-C8' catalyzed by ntnA (Probable). The terpene cyclase/mutase ntnI then initiates the sequential tricyclic ring formation through protonation of the terminal epoxide and catalyzes the regioselective and stereoselective 6/6/6-tricyclic ring formation (Probable). The cytochrome P450 monooxygenase ntnM may then hydroxylate C1' (Probable)."}]}
+{"id": "function_test_1802", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLPTVFIVSDGTGITAETFAHSILSQFDQKFRLVRVPFVDSLDKAYATVEKINEAAVHDGRRAIVFTTLVDSESNDIVKRSNALVLDMFQRFVEPLEQELELKSSHAMGRGHQNADTEEYKTRIEAINFSLAHDDGQSNRNLSEADVILVGVSRSGKTPTSLYLAMQYGVKAANYPLIPEDFERGKLPSALAPYSEKLFGLSIDPQRLSEIRNERRPGSKYAAPENCRYEINEAEAMMRREGIKWLSSTHKSIEEIATTILQEIRLDRQSY", "output": "Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation."}]}
+{"id": "function_test_1803", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNHFPKLLSSQIGFDVAQTMLEYFDRHYRIFREAAVDAKTLFERGDWHGLQRLARERITSYDERVKECVEVLEDEYDAENIDDEVWQQIKLHYIGLLTSHRQPECAETFFNSVCCKILHRSYFSNDFIFVRPAISTEYLENDEPAAKPTYRAYYPGTDGLAVTLERIVTNFQLDPPFEDLTRDIGCVMQAIDDEFGHFDEAPNFQIHVLSSLFFRNKSAYIVGRIINADRVLPFAVPIRHVRPGVLALDTVLLRRDLLQIIFSFSHSYFLVDMGVPSAYVDFLCTIMPGKPKAEIYTSVGLQKQGKNLFYRDLLHHLSHSSDRFIIAPGIKGLVMLVFTLPSFPYVFKIIKDHFPPPKETTRAQIMEKYQLVKRHDRLGRMADTLEYSSVALPLARLDHALVRELEKEVPSLLEYEDDKLVIKHLYIERRMTPLNLYLQNGSDADVEHGVKEYGNAVKELMKANIFPGDMLYKNFGVTRHGRVVFYDYDEIEYLTDCNVRRVPPPRNEEDELSGEPWYTVGPHDIFPETYGPFLLGDPRVRSVFMKHHADFFDPALWQASKDKLMQGELPDFYPYDATLRFSVRYPARFGATGENDGAGDAQRAA", "output": "Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation."}]}
+{"id": "function_test_1804", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAQFFKPQKKSTQPQRIEFTVDSLDHHCVGIGRHQGKAIFIEGALPGELVKARILEDKKQYAHAALQQVVTPAANRIAPFCSHYRECGGCSAQHLAEADQRAAKEAGLVSLFERLGNIQPPALEPVLGGESRAYRRVCRLAIKFDKNGRCTRVGFRRRQSNDLVEIGGCPVLAEPLSVLITPLRECLNRLKSQRELGHVELIQAEQGILMLLRHTGRPTEADRAQLIEFAKTQGIDLYLQAADEQIEPLHQQFAPSYSLDGLSLAFAPGDFIQVNAPVNQRMVEQALSWLEAGKDDKVLDLFCGIGNFTLPLARQAREVVGVEGELAMVARAEENARRNGINNARFYKADLGGDIAGMSWAREGFDLVLLDPARPGAFEVMEHVVKLSPRRVVYVSCNPVTLARDSQVLVKGGYRLVRLGMLDMFPHTGHLESMALFERK", "output": "Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA."}]}
+{"id": "function_test_1805", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MADGLNRVHYNPSTAQLVEFALLRGEGELTANGALVAKTGTRTGRSPGDRFIVKEDSSAADIEWGPVNQAFEPGAFEGLWARVEAFLADKELFVSDLEVGADPEHYQPVRVTTQYAWHQLFARNLFIIPEEFNRQDKPVWQIINAPDFVCVPERDGTNSDAAVILNFAERKVLLAGLKYAGEMKKSMFSVQNFLLPAQGVLPMHCSANVGKDGDTTLFFGLSGTGKTTLSADPKRFLIGDDEHGWAPGGVFNIEGGCYAKCIDLSQKNEPVIWDAIRFGTVLENVVMDEHRVPNYKDSSLTENTRAAYPLEHIAQRKEDNRGAEPHAVVFLTCDVSGVLPPVSILSKEQAAYHFLSGYTAKVGSTEIGSTSAIQSTFSTCFGAPFFPRPAGVYAELLMKRIESFGSQVYLVNTGWTGGPHGIGKRFDIPTTRAIVDAIVSGELKNVETVHLETLNLAVPVAVPGVDTNLLNPVNTWSDKALYAEYAQKLAEAFTKNFAKYQVSDAIRNAGPKA", "output": "Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA."}]}
+{"id": "function_test_1806", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNGSMPFHKYSPYPPVALANRQWPNRTLTKAPLWCSVDLRDGNQALANPMGPQAKRRMFDLLVEIGFKEIEVGFPSASRDDFQFLRDLIEQKAIPDDVTVQMLVQSRAHLIERTFEALQGAKRAIVHLYTPTSSLQRRVVFGKSQQEIIDVAVEGTQMIKEHAQRSPETEIVLEFSPESFTGTELPFALAISEAVQQVWQPTPAQPMILNLPATVEMSTPNIYADQIEWMLSHLSDPQSIIISLHAHNDRGTAVAATELAMLAGAGRVEGTLFGNGERTGNTDVVAVAMNLHSQGIDAGLNFSEMPRIIATSEACTGMSVPPRQPYAGELVFTAFSGSHQDAIRKGLHLHKQEQAQQWAVPYLPIDPQDLGRHYEPVIRINSQSGKGGMAFIMEERCGIHMPKAMQVEFSRVIQAVTDEMGRELQADEIEQLFFKNFVLQENPLSLGHVEHREETEERHHLHAQVSYAGTVQALQAHGNGPMSALVNALETFYSMTIQIHDYHQHARTAGRDSEAVSFVQISVNGGKPTFGVGLHTDSSRSALEAVLCSINRALATSLT", "output": "Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)."}]}
+{"id": "function_test_1807", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRVAIYPGSFDPITEGHLDIIKRASKVFDEVIVSVLVNPDKKGLFSIEERVKLIEKVTEDIDNVKAESFEGLLVDYMKEKDAKVIIKGLRVVSDFEYELQMAHMNKKLDSSIETVFMMTNAKYSYLSSSSIKQVVMFGGCIEGLVPNKIIKDIINKIGKVR", "output": "Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate."}]}
+{"id": "function_test_1808", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSVLLFGVSHRSAPVSVLEQLSTNEAEQAKIIDQVLQSSLVTEAMVLSTCNRVEVYAVVEAFHGGLSVIGQVLAERSGMSLNDLTKYAYVRYAEAAVEHLFAVTSGLDSAVIGEQQVLGQVRRAYATAEANRTVGRTLHELAQRALSVGKRVHSETGIDAAGASVVSVALGMAETKLSGGLGGRTAAVVGAGAMGALAGAHLVRAGIERVHVVNRSLPRAERLAKNLTEQGVVADAVGLDDIARALVDADVVLSSTGAVRPVVSLADVHYALAQRTLAGAEHQMVVCDLGMPRDVDPAVSGLPGVWVVDMDRIQREPSARAAAVDAEAARNIVAAEVANYLAGQRMAEVTPTVTALRQRAADVVEAELLRLDNRLPGLDAAHRDEVAKTVRRVVDKLLHAPTVRVKQLASAPGGDSYAEALRELFELDPQAVEAVAASELPLITTDLDKTE", "output": "Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA)."}]}
+{"id": "function_test_1809", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRVAMMTREYPPEVYGGAGVHVTELVAQLRKLCDVDVHCMGAPRDGAYVAHPDPTLRGANAALTMLSADLNMVNNAEAATVVHSHTWYTGLAGHLASLLYGVPHVLTAHSLEPLRPWKAEQLGGGYQVSSWVERTAVEAADAVIAVSSGMRDDVLRTYPALDPDRVHVVRNGIDTTVWYPAEPGPDESVLAELGVDLNRPIVAFVGRITRQKGVAHLVAAAHRFAPDVQLVLCAGAPDTPQIAEEVSSAVQQLAQARTGVFWVREMLPTHKIREILSAATVFVCPSVYEPLGIVNLEAMACATAVVASDVGGIPEVVADGRTGLLVHYDANDTEAYEARLAEAVNSLVADPDRAREYGVAGRERCIEEFSWAHIAEQTLEIYRKVSA", "output": "Involved in the biosynthesis of the maltose-1-phosphate (M1P) building block required for alpha-glucan production by the key enzyme GlgE. Catalyzes the formation of an alpha-1,4 linkage between glucose from ADP-glucose and glucose 1-phosphate (G1P) to yield maltose-1-phosphate (M1P)."}]}
+{"id": "function_test_1810", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSQEKQVFSIDLAGRQLTVETGQLAKQANGAVLVRYGDTAVLSTATASKEAKNVDFFPLTVNYEERLYAVGKIPGGFIKREGRPSEKAILASRLIDRPIRPLFADGFRNEVQVVSIVMSVDQDCSSEMAAMLGSSLALSISDIPFEGPIAGATVGRINGEFVINPTVEQQEQSDIHLVVAGTKDAINMVEAGADQVPEETMLEAIMFGHDEIKRLIAFQEEIVQAVGKEKSEVKLYEVDADLNQAVREMAEKDMHSAIQVHEKHAREDAINEVKKRVIEHYEAQEADADTLGQVNEILYKIVKEEVRRLITVEKIRPDGRKGDEIRPLASEVGILSRTHGSGLFTRGQTQALSICTLGALGDVQILDGLGVEESKRFMHHYNFPSFSVGETRPMRGPGRREIGHGALGERALEPVIPSEKDFPYTVRLVSEVLESNGSTSQASICGSTLAMMDAGVPLKAPVAGIAMGLVKTGEHYTILSDIQGMEDHLGDMDFKVAGTAHGVTALQMDIKIDGLSREILEEALQQAKVGRVHILNHMLSVIAEPRTELSAYAPKIITMTINPDKIRDVIGPSGKQINKIIEETGVKIDIEQDGTVFISSINQEMNDKAKKIIEDIVREVQVGEIYEGKVKRVEKFGAFVELFSGKDGLVHISELALERVGKVEDVVKIGDVITVKVIEIDKQGRVNLSRKVLLKEEQEKEAAKEENKQEQQ", "output": "Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction."}]}
+{"id": "function_test_1811", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTENKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA", "output": "Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis."}]}
+{"id": "function_test_1812", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRCPSLARLPHRAISGLTRLPVRLQSQTFLYQRCASTAALRSPTAGPAYQSILNRHNLQRRNASAAAAAVLEAAASNPDALTQEAIIDNLDPVEATRLSRIRNIGIAAHIDSGKTTCTERILFYTGRIKAIHEVRGRDNVGAKMDSMDLEREKGITIQSAATFCDWVKKEDDGREEKYHINLIDTPGHIDFTIEVERALRVLDGAVMILCAVSGVQSQTITVDRQMRRYNVPRISFINKMDRMGANPFKAVDQINSKLKIPAAAVQVPIGAEDEFEGVVDLIRMKSIYNHGPSGEEIVIKDEIPEKVKSVVEERRRMLIETLADVDDEIAELFLDEKEPTQEQLKAAIRRATVGLKFTPVFMGTALSNKSVQPMLDGVIDYLPNPSEIENLALDQKRNEASVKLVPYNSQPFVGLAFKLEESNFGQLTYIRVYQGTLRKGANVFNARNNKKVKIPRIVRMHSNEMEEVSEIGAGEICAVFGVDCASGDSFTDGQLGYTMTSMFVPEPVISLSIKPKNNKDSANFSKAMARFQREDPTFRVTYDAESEQTLISGMGELHLDIYIERMRREYRVDCETGPPQVAYRETIGNKVEFDHLLKKQSGGPGDYARVVGWMEPTDKLEENKFEEQIVGGSISEKFLFACEKGFNLACEKGPLIGHKVLGTRMVINDGATHMTDSSEMSFKNATQQAFRKAFMESNPSVLEPMMKTVVTAPSEFQGDVISLLNKRNATINDTETGVDEFTVYADCSLNGMFGFSSHLRAATQGKGEYTMEFSHYEKAQPQLQKELIQKYLKAQADRHKK", "output": "Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome."}]}
+{"id": "function_test_1813", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTKTWPPRTVIRKSGGLRGMRTLESALHRGGLGPVAGVDEVGRGACAGPLVVAACVLGPGRIASLAALDDSKKLSEQAREKLFPLICRYAVAYHVVFIPSAEVDRRGVHVANIEGMRRAVAGLAVRPGYVLSDGFRVPGLPMPSLPVIGGDAAAACIAAASVLAKVSRDRVMVALDADHPGYGFAEHKGYSTPAHSRALARLGPCPQHRYSFINVRRVASGSNTAEVADGQPDPRDGTAQTGEGRWSKSSHPATMRATGRAQGT", "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."}]}
+{"id": "function_test_1814", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKFELDTTDGRARRGRLIFDRGTVETPAFMPVGTYGTVKGMTPEEVRATGADILLGNTFHLWLRPGEEIMRKHGDLHDFMNWQRPILTDSGGFQVFSLGDIRKITEEGVHFRSPINGEKIFLDPEKSMQIQDALGSDVVMIFDECTPYPATEDEARKSMQMSLRWAKRSRDEFDRLKNPNSLFGIIQGGVYEDLRDESLKGLVEIGFDGYAVGGLAVGEPKADMHRILEHICPQIPADKPRYLMGVGKPEDLVEGVRRGVDMFDCVMPTRNARNGHLFTSEGVIKIRNARHRDDTSPLDTKCDCYTCKNYSRAYLYHLDRCNEILGARLNTIHNLRYYQMLMEGLRGAIETGTLDAFVADFYTSQGREVPELVD", "output": "Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)."}]}
+{"id": "function_test_1815", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVEKIRIIGIDPGLRRTGWGIIDFLGNHMHFVASGTLHSDAQLNLASRLHQLHKGLSEVVHQFMPHEAAVEHVFVNKDATATLKLGQARAIALLVPAQAGLPVFEYAPNTIKKSVIGVGHGAKEQIHMMVKRLLPRAEFDGHDAADALALVICHSAHRTNFAHRIKG", "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."}]}
+{"id": "function_test_1816", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MFKTHKVEIEWAGRPLTIETGRVARQADGAVVATYGETVVLATVVSAKAPKPDQDFFPLTVNYQEKTYAVGKIPGGYFKRESRPSENETLISRLIDRPIRPLFVDDYKNDTQVIVSVIQHDLENNPDILSMIAASAALTLSGIPFMGPIAGARVGYCNGHYVLNPTLDEMPESKLDLVVAGTENAVLMVESEAHELSEEVMLGAITFGQKGFQPVIDAIIQLAEVAAKEPREFIPEDFSDLEKTMLKMIEKDLRKAYTITDKQQRYDAIDAIKTEILSKFAPEMEVNCELTADKIATVFKRLQAKIVRWNILDTGKRIDGRDLSTVRPIQSEVGILPRTHGSALFTRGETQALVVATLGTSEDEQYVDLLTGVCKETFLLHYNFPPFSVGETGRLSSPGRREIGHGKLAWRAIHPMLPTKEAFPYTIRVVSEITESNGSSSMATVCGTSLALMDAGVPLARPVAGIAMGLIKEGERFVILSDILGDEDHLGDMDFKVAGTKNGITSLQMDIKIDGITEDIMKIALEQAKDGRNHILNEMAKALTDARTELSEFSPRIEMMTIPVEKIREVIGSGGKVIREIVEQTGAKINIEDDGTIKIASPDTKSIETAKSWIHSIVDEPEVGTIYQGTVVKTTEFGAFINFFGSHDGLVHISQLASKRVAKTTDVVKEGDKVWVQLMGFDERGKIRLSMKVVDQQTGKEIPQDDLIKTEKEQNPDEKNKSEKKRHNRKKED", "output": "Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction."}]}
+{"id": "function_test_1817", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNVIRARTAGFCMGVSLALRKLDREVDRAEEKAAQGSPRCRIATFGPIIHNPQVLEAYAGMGVRCLRQVDEVEAGDHVVIRAHGVPQQQEKALRSRDAVVVDATCPKVKKAQLGIEEQCRAGRTLLLFGEAEHPEVRGLLSYAGEGALVFGSVDELEGLPLQPETEYFLAAQTTQDRVAFEAARAWLHERLGHEVPVLETICDATRLRQQEAIDIARKVDAMVVVGGFDSGNTRRLADVAAAQGVFTVHVENESQLPVEQLRGCGIIGLTAGASTPKSIIDATQRFLESL", "output": "Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis."}]}
+{"id": "function_test_1818", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIEETQTPSPPAPAPAPAEYPIDLLTVESLDIEAQGIAHRADGKVVFIEGALPFEQVTANVYRKKSSFEKATLTAIYRESSQRVTPACPHFGMHTGACGGCKMQHLHIGAQVAVKQRVLEDNLRFIGKVKADNLLRPIEGPAWHYRYRARLSVRYVRKKGTALVGFHERKSAYVADMTECHVVPQHVSDMLVPLRGLISSMDARETIPQIELACGDDLTAMVLRHMEPLSVADLARLRAFAAANAGLQWWVQSGGLDTVKLLDAQVAELSYGLPEFGITMPFKPTDFTQVNPHINQVLVSRALRLLGVQPTERVIDWFCGLGNFTLPLATRAREVLGIEGSEVLVARSRENYERNKASSHVRPALEATKFVARNLFEMTPAMLVKDGAAEKWLVDPPREGAFELFKSLAALHQQVVTGVPCDDGIHQQSLALGGWTPPSRIVYVSCNPATLARDAGVLVEGGGYRCTAAGVVNMFPHTAHVESMAVFERL", "output": "Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA."}]}
+{"id": "function_test_1819", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQVSVETTEGLGRRMTVQVPAERVENEVERRLKDLSGRVKMDGFRPGKVPVKVVRKQYGAQVRSEVLSEVVQQTYSEALEQESLRPAGNPHIEPKRTGEGEDLEYEASFDVLPEIEVAGLDQIQVERPQVEITDADLDNVLERLRKQHADYQEVDRAAQDEDRVVIDFHGTIDGEAFTGNSAEDAPLILGAGQLPEAFEQGLQGAKAGQELTVEHKFPDELAEPSIAGKTAVFQVTVKRVEEPQLPELDDDFAARLGIQEGGVEALREAVRGNLERERHQAVRQRLKRQVLDQLADQNELELPKSLIDGEIQALRQQSGASAEGELPESERSAYEDVASRRVKLGLLVNELVRSQGIQLDRERMMTQLREMAANSGQDPSEALQQIAQDRQMMQSLEASVIEEQVVDWLLEQVQTEDKTLSFDELMNSEDGDQASA", "output": "Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase."}]}
+{"id": "function_test_1820", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MATKFPSFNQGLAQDPTTRRIWYGIATAHDFESHDGMTEEKLYQKLFSTHFGHLAIIALWVAGNLFHIAWQGNFEQFVLDPTHVRPIAHAIWDPHFGSGITEAMTQAGASGPVNIAYSGLYHWWYTIGMRTNEQLFQASIFMSILACWTLFAGWLHLQPKFRPSLAWFKNAESRLNHHLAVLFGFSSIAWTGHLVHVAIPESRGQHVGWDNWLTVLPHPAGLAPFFTLNWGAYAQNPDSLDQVFGTAEGAGTAIFTFLGGLHPQSEALWLTDIAHHHIAIGTVFVIAGHMYRNTFGIGHSLKEITEAHNTRHPNDPHKGSFGINHDGIYETVNNSLHFQLGLALASLGVATSLVAQHMGALPSYAFIARDYTTQSALYSHHQYIAMFLMVGAFAHGAIFFVRDYDPELNKDNVLARVLGTKEALISHLSWVTMLLGFHTLGIYVHNDVVVAFGNPEKQILIEPVFAQFVQAAQGKMMYGFNALLSDPTSSASLAANSLPGNHYWMDLINRQDALSAFLPIGPADFLVHHAIALGLHTTALILIKGALDARGTKLIPDKKDLGYAFPCDGPGRGGTCDSSSWDAMYLAMFWALNLLAWVTFYWHWKHLAIWQGNVAQFNESGTYLMGWFRDYLWLNSAQLINGYNPFGVNSLSPWAWMFLFGHLVWATGFMFLISWRGYWQELIETLVWAHQRTPIANLVGWRDKPVALSIVQARLVGLAHFTIGNILTFGAFVIASTSGKFG", "output": "PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6."}]}
+{"id": "function_test_1821", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRKPVIAGNWKMHMTCAQAREYTAMFLPLIEATPNDRHVVIAPPFTAISSMAEAVGGTRLELSSQNVHWEDDGAYTAEVSPTMLLEHQVRYAIVGHSEPRKYFSESDEQINRRARSAQAHGLIPIVCVGESDEQRERGEAERVIRRQVEQGLEDTDPDKLVVAYEPIWAIGTGKTCEASEANRICGLIRGWVGASELIIQYGGSVKPGNIDELMAMSDIDGVLVGGASLDPESFARIANYQTS", "output": "Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)."}]}
+{"id": "function_test_1822", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRALYPGSFDPLTLGHLDLIERGCALFGEVVVAVLSNPAKTPAFTLQQRFNQIHVATAHCKGVSVISFDGLTVRCARHNQVDLILRGLRAMSDFEYELQIAHTNRSLAPDFETIFLATAAHHSFLSSSMVKEVARFGGNIDHMVPEVVAQDLHRLFN", "output": "Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate."}]}
+{"id": "function_test_1823", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAAAVAMRSGSGSDGGGGGYDKAGMDSGKYVRYTPEQVEALERVYAECPKPSSSRRQQLLRDCPILANIEPKQIKVWFQNRRCRDKQRKEASRLQAVNRKLTAMNKLLMEENERLQKQVSQLVHENAYMKQQLQNPSLGNDTSCESNVTTPQNPLRDASNPSGLLTIAEETLTEFLSKATGTAVDWVPMPGMKPGPDSFGIVAVSHGCRGVAARACGLVNLEPTKIVEILKDRPSWFRDCRSLEVFTMFPAGNGGTIELVYMQMYAPTTLVPARDFWTLRYTTTMDDGSLVVCERSLSGSGGGPSTASAQQFVRAEMLPSGYLVRPCEGGGSIVHIVDHLDLEAWSVPEVLRPLYESSRVVAQKMTTAALRHIRQIAQETSGEVVYALGRQPAVLRTFSQRLSRGFNDAISGFNDDGWSVMGGDGIEDVIIACNAKKVRNTSTSANAFVTPGGVICAKASMLLQSVPPAVLVRFLREHRSEWADYNFDAYSASSLKTSSCSLPGLRPMRFSGSQIIMPLAHTVENEEILEVVRLEGQALTHDDGLMSRDIHLLQLCTGIDEKSMGSCFQLVFAPIDELFPDDAPLISSGFRVIPLDMKTDGTPAGRTLDLASSLEVGSTAQPTGDASMDDCNLRSVLTIAFQFPYEMHLQDSVATMARQYVRSIVSSVQRVSMAISPSRSGLNAGQKIISGFPEAPTLARWICQSYQFHLGVELLRQADDAGEALLKMLWDYEDAILCCSFKEKPVFTFANEMGLNMLETSLVALQDLSLDKIFDEAGRKALYNEIPKLMEQGYVYLPGGVCLSGMGRHVSFEQAVAWKVLGEDNNVHCLAFCFVNWSFV", "output": "Probable transcription factor."}]}
+{"id": "function_test_1824", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKQIALYGKGGIGKSTTAANLSAALAGEGLDILQIGCDPKHDSTRMLMHGTWIPTVLDLIRERGDEKITVDDVVYRGFRGVRCVEAGGPEPGIGCAGRGIIATFQLLERLNALKGDVIVYDVLGDVVCGGFAMPMREGYAQEIYLVTSGELMSIYAANNIAKAIARLSRRVRSRCTLGGVICNAKNIEGERELVDEFARRIGSRLIAYIPRSRIVQVAELQKQTVVEYAPESDQAAVYQELARTVYGNETTSIPTPLEMDELESFALEFVQV", "output": "The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein."}]}
+{"id": "function_test_1825", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKQNSLNVKQKKLSKIAFSHVGCEKNLVDTEHMQGLLHKEGYEVDSNINDANVVVVNTCSFIETAREESIRKILEYTNQGKEVIVAGCMAQHFKDELIKEIPEIKGLVGTGDYQKIAKVLDRVEKGEIVNEVSKIPEFIADEEMPRFVDKNKFVAYLRIAEGCNYNCAFCIIPKLRGPQRSRTIESILSEAKSLAKKGIQEIILISQITTNYGQDIYGKPSLAKLLNELSKVPIPWIRIHYAYPTGLTDEVIRAFKDSKNIVPYFDLPLQHSHPDVLKSMNRPWQASLNESILEKIREEIPSAVLRTSLIVGFPGEKKEHFEHLLQFLDRHKFDHVGVFIFSPEEGTAAFHLPNKVSPEVAEARKDNVISVQQNISREKNQIYVGSKMKIMVEQISDNNELIGRSYNFAPEIDGTVILSVKEKIDLKNYIGKFVEANISFADEYDLYGETIKIL", "output": "Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12."}]}
+{"id": "function_test_1826", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSKKNNLLVAASGTGGHIFPALAVTKEVEDKWNIHWLGVHKRLDANFIPKKYNLRTLNIKTPRKNIFLFYQYFRILMSTFQVIWILKEEKINLVFTTGGYISAPTIIASKLLRIPVIIHESNLIPGMVTKNFGFLCNYVLLGFKRTNSYLKNCKTIFTGTPLREQFYKSNLLPDWVPQGKGPLLIVMGGSQGAKAINQILYESLDFLMKKQFRIVHIIGECNQKYFNLNTSNNYVQKKFTNEIAALIQNCDLVISRSGAGTINELIESEKPSILIPYPNSKNNHQEKNAMILAESGGSILINQNNISKEVFEETLERIFKIKSKKGKNHYEILDLMKKNMENNKKIKSKIEIKKFINYFLKEF", "output": "Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II)."}]}
+{"id": "function_test_1827", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTAIQHFFKTFFLTELLKGLALTGRYTFRRKFTVQFPEEKTPISPRFRGLHALRRYENGEERCIACKLCEAVCPAMAITIESETRADNTRRTTRYDIDLTKCIFCGFCEESCPVDSIVETQILEYHGEKRGDLYFTKEMLLAVGDRYEKDIAAAKAADAPYR", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_1828", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNAPQTNDTAADGAATEAIAADSGRRALTRREQKEAYENNKLFKRIARQVGQAIGDYNMIEAGDKVMVCLSGGKDSYAMLDVLLRLRERAPIDFDIVAVNLDQKQPGFPEHVLPEYLTQIGVPFHIENQDTYSIVKRLVPEGKTTCSLCSRLRRGILYRVAGELGATKIALGHHRDDILQTLLLNMFYGGKLKGMPPKLQSDDGRNVVIRPLAYVKETDLEKYAELREFPIIPCNLCGSQPNLKRAEMKALIREWDKRFPGRVDNMFSALANVVPSHLMDTGLFPFASLRATGVADPLGDIAFDEEPCASGDATGDAAGNTTSGAARPISIVQFDDL", "output": "Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system."}]}
+{"id": "function_test_1829", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MVKGVKGRPNVLAIVLAGGEGKRLFPLTEDRAKPAVPFGGTYRLIDFVLSNLVNSGFLKIAVLTQYKSHSLDRHISLSWNVSGPTGQYIASVPAQQRLGKRWFTGSADAILQSLNLISDEKPDYVIVFGADHVYRMDPSQMLDEHIASGRAVSVAGIRVPREEATAFGCIQSDDDGNITEFLEKPADPPGTPDDPDMTYASMGNYIFTTEALIQALKDDENNENSDHDMGGDIIPYFVSRNDAHVYDFSGNIVPGATERDKGYWRDVGTIDAFYECHMDLISVHPIFNLYNSEWPIHTTSEGNLPPAKFVRGGIAQSSMVSSGSIISAGTVRNSVLSNNVVVEEGATVEGAVLMPGVRIGKGAVVRHAILDKNVVVRDGELIGVDHVRDAQRFKVSAGGVVVVGKNQVV", "output": "Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc."}]}
+{"id": "function_test_1830", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGSDYDSFDDDVADEVLMALDKPATSGLHSREQEQQRDISNATPHTSTDLELEDFGSDAFDYSPERERAKPIQTARNQARTFQQTTLLGRIASQAPEPLGTQPRNSRVFRADLPPEVPTHHALDPEALKTWVYPTNLGPIRDYQFSIVKNGLFNNTLVALPTGLGKTFIAATVILNFFRWTRNAQMVFVAPTKPLASQQVEACLNIAGIPRSQSTLLTGETKPVLREAEWEGKRLFFMTPQTLMNDLSKGYADPKRIVLLVVDEAHRATGDYAYVKVIEFIRRFSKSFRVLALTATPGSTVEGVQDVIDNLGVSHVEIRTEESIDIRNYVHSREIDRVVLEPSDEMLRISELFSQALKPLHSKISQQKIYIGRDPMSITTFGLLKARQDWMKGPGRFANQGLKMMLMAIFTILQSLAHAIKLLNYHGIRPFYDNLVAFRSETEDKGQKGSKYKRQLIGEQSFQEMMDLASKWLKIDGFAGHPKLTHLCDNLLNYFMDAGEGSSTRVIVFSEYRDSAEEITRVLNVHKPMISASLFVGQADSKKSEGMKQKQQIETIAKFRDGIFNVLVATSIGEEGLDIGQVDLIICYDASSSPIRMLQRMGRTGRKRAGKITLLLMKGKEEDNYAKAQDNYEKMQKLICEGSRFNFRHDLSSRIVPRDVKPEVDKRMVEIPIENTQDTSLPEPKARSTRGKKASKKKFNMPDGVETGFNSVASMLGISASKTKAKPNKSPKKAESKETDEISPVPPLEGVLLSVKELAELNKKYRDLPFFHQDTEEICMPSLTARPDLQRVLRPTVHVKHGSYTKRCVRLFKKLSHSQGIETRHTKPHGDTDKSRYLDISVPPFAEDSGEDVVVVPSGRKRSLSPSSAASPPPPGRKRKANTTAAPRSKRQSVVDEYASESEDDTAAARQRKTNAAASPESKRQSVLDEYASESDAEAVTQASEDEESVGSLADFISDGEANGNFPKDMTGFTSDEDDDYRSGSLAKSSLSGPLSGRQVHRSSGAASKSGSTASTAAKPFFVPASLPGTQQTDDDEDMPDIGILVGKKQPETRVRKPAKKSNAVFLSSDDDDDDNDDEDDVQPGPAKRTVRRRVIEDSESG", "output": "ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork."}]}
+{"id": "function_test_1831", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLAKRIIPCLDVKDGQVVKGVQFRNHEIIGDIVPLAQRYAQEGADELVFYDITASSDGRVVDKSWVARVAEVIDIPFCVAGGIKSVEDASQILTFGADKISINSPALADPTLITRLADRYGVQCIVVGIDTWYDTESDSYQVYQFTGDEKRTKATTWQTEDWVKEVQLRGAGEIVLNMMNQDGVRNGYDLRQLQQMRAICHVPLIASGGAGTPDHFLEAFRDADVDGALAASVFHKKIINIGELKKYLSEQGVEIRVC", "output": "IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit."}]}
+{"id": "function_test_1832", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIVVKIGGSVICKDASRVIQNLPKYADKAVVVHGGGCLVNEVMKKMGIEPKYLTHPGGLVSRYTDLETLKAFVMAMGWINKYIVASLHALGVEALGLTGADLGVVKAKRKERVLVVDERGRQRVVDGGYVGRITEVDAAKLAPPPLKVLAPLAVSERGELLNVDGDQLAFDVARGVKADKLVLLSDVDGLYIGGKVVPRLTAEEAEALVKSEEVRGGMKRKLLMAAEAAKLGIEVIISNGLADLPIDSALNGGGTHITKNL", "output": "Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis)."}]}
+{"id": "function_test_1833", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNLYEYLSQGIKHFTLIDPDKSVDYLRIARYALEAGTDGILVGGSLGITASQMEKVVKDIKSVANVPVVLFPGSLSQLTDAADGVLFLSVLNSLDPYFIIGAQVHGAVLIAKHYPRLEVISTAYVIVGDGGAAGFVSMSKPIPYTRPDIATAYALAAGYIGFKALYLEAGSGAPQPVPPDMVRAVRKAFPRVLIVGGGIRSSEVARSIAREGPNVIVTGTLAEESPEKLGEIVRAIKQR", "output": "Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids."}]}
+{"id": "function_test_1834", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKHFEFENDKLIVLDQRKLPFEKEYFVCSTYQDVYIAIKDMIIRGAPLIGIVAAYGVVLGFKEIIEKNMDSAKIYEILNYLANSRPTAVNLFWALERMKKVFEEARNLSKSQIYSLLMQEAKKIEDEDKSINKKIGEHGNTLIKEGANILTHCNAGALATGGYGTALGVIREAFFAGKNIHVYVDETRPYLQGARLTAFELSEDGIPNTVICDNMAGYLMKLGKIDCVIVGADRIALNGDTANKIGTYSLSVLAKHHGIPFYISAPISTIDFNIKSGSEIPIEERSEDEIRFFNGKKIVPDESKVFNPAFDVTPAENITAIITEKGVVFPPFEENISKLKEK", "output": "Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P)."}]}
+{"id": "function_test_1835", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPKTAKPKKPVDVAELTKAQAKVEWKRLALELEVHDRLYYQDDAPKISDAEYDELRRRFNAIETRFPELVSSESPSQKVGASPSGRFKKVRHAVPMLSLDNAFAEEDVRDFVGRIARFLKLADDRIDFSAEPKIDGLSMSLRYEGGELVTAATRGDGAEGEDVTANIRTLKDVPQKLHGRNWPDVCEVRGEVYMTKQAFLALNERQKEAGDTIFANPRNSAAGSLRQKDPAITASRPLGFFAYAWGEISGTPPAETQTGMIKWFEQCGFTTNPLTRLCHSVEELIAFHRSIEEQRAELDYDIDGVVYKVDRIDWQERLGFVSRTPRWAIAHKFPAERAMTVLKDIEIQVGRTGSLTPVGKLEPVGVGGVIVQNVTLHNEDYIKGIGNKGEVLREGRDIRIGDTVVIQRAGDVIPQVVDVVIDKRPAQARPFHLPKTCPCPLHTDVVREETATGEEGSRARCTGEFACPYQKIEHLKLFASRRAFDIDGLGEKQIAFFFEQGWVKEPADIFTLQKRNAGLKLEEIEGYGETSVRNLFNAIDARREIALERFIYALGMRHVGETTALALARGYGSWDAFHEACLKVAAGDEEAIAEMDALDQIGDTVIKSVAAYFAEDHNRGIVERLTQEVKILDAEKPKRHSPIATKTVVFTGTLEKMTRDEAKATAERLGAKVSGSVSKKTDYVVAGPGAGSKLKEAQKHGVQVLTEDEWLQLIAE", "output": "DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA."}]}
+{"id": "function_test_1836", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSTFYTVLPILFLAIAGMIMLMSGVFTDRDHSFAITAASIVVLAIAARLLVAAPGGTIFHGLYQTNDFTRFADVLVALGAIGALALSVTFNRNIGITRFEFPVLVLFAVTGMVVLVSASDLITLYIGFEIQSLALYVLAAFARHNLRSSEAGLKYFVLGALSSGLLLYGISLVYGFAGTTNFAGIAHALAGHPTAAVGSTIGLVFVLVGLAFKISAAPFHMWTPDVYEGAPTSVTAFFATAPKIAVFALLLRVMLGPFGPVLGQWRDLVQIIAAASMVIGAIGAIRQTSIKRLMGYSSIGHMGYALMGLAAGTAAGVSGALIYLAIYLVMSLGTFGCIIAMSRGRQPVERIADLAGMASDDPRFAFVLAVMMWSMAGIPPLAGFFGKFYVFAAAINAGLGPLAVLGIITSVIAAFYYLRVIKVMYFDAGEPGLDRRSAGVSLVMGAAAAFTVLFVFHPSTLTTLSTMAAHALMTSQGF", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_1837", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MYSQTKIAIPIFQAKKEDVIKVAEDCIEKGADVLEFRIDALDNPNFDDIKEIIEEINFPIIATNRISSEGGSFKGSEEERIDILLKCAPLVDYVDIELQSDDRYIKQIHDTGVTTIVSYHDFHKTPEINEIMYIVEKEQKLGDIAKVAFMPNDLDDTLKILAILSHCENTIAISMSDLGSYTRVMASKFDSPITFAAGRDVTAPGQIDIETMKSLLNMDLNLME", "output": "Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate."}]}
+{"id": "function_test_1838", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVIKMTETGGNYDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDDRLIYTANDLKVGLFQDTSAF", "output": "Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length."}]}
+{"id": "function_test_1839", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGEIIKGKPVADKISEDLIQEIEGLKGKGIQPKLAIVRVGANSSDLAYEKGALGRSKKVGVETEVHELPEDITQDDFIKELKKLNEDKAVNGILIFRPLPEQLDESVIKYVIAPEKDIDCLSPINVGKMTEGDKTGFPPCTPTAVVEILKFYGVELQGKDCAIIGASMVVGKPAALLLLNENATISVCHIFTKDSAKIASQADVVVVGVGVPRLVKENWIANGAVVIDVGINVDKEGNMCGDVDFDGVKDKVSMITPVPGGVGSVTTSILAKHVVKACKQQNNL", "output": "Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate."}]}
+{"id": "function_test_1840", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNYPNGKPYRKNSAIDGGKKTAAFSNIEYGGRGMSLEKDIEHSNTFYLKSDIAVIHKKPTPVQIVNVNYPKRSKAVINEAYFRTPSTTDYNGVYQGYYIDFEAKETKNKTSFPLNNIHDHQVEHMKNAYQQKGIVFLMIRFKTLDEVYLLPYSKFEVFWKRYKDNIKKSITVDEIRKNGYHIPYQYQPRLDYLKAVDKLILDESEDRV", "output": "Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation."}]}
+{"id": "function_test_1841", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRPNNRAINQPRPIKITRHYTKHAEGSVLVEFGDTKVLCTATVDESVPRFLKGQGQGWVTAEYGMLPRSTHSRMQREAAKGKQGGRTMEIQRLIARSLRAMVDLEALGERSVTLDCDVIQADGGTRTASITGACVALIDAVNGLVDNGTLTVSPLKGLVAAISVGIVDGTPVCDLEYVEDSAAETDMNVVMMEDGRMIEVQGTAEGEPFSHEELLTLLNLAKQGCKRIFEAQRAALAD", "output": "Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation."}]}
+{"id": "function_test_1842", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSSLYQKLSRRIGYFFADLGLLELALTHRSFGGKNNERLEFLGDSILNYVIAEDLFHRFPKAKEGELSRLRASLVKGDTLAELAREFELGDYLKLGAGELKSGGFRRDSILADTVEGIIGAMYLDAGMDVCRQHILAWYKERLDATSLKIVTKDAKTRLQEFLQARKHALPQYDVVNIVGEPHDQTFYVHCHIELCEEFIEGKGNSRRIAEQNAAAKALKKLEKKDV", "output": "Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism."}]}
+{"id": "function_test_1843", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSENKCPMHHSAGGTTNRDWWPKQLRLDILHQHSSLSNPMGDDFNYAEAFKSLDLAAVKQDLLALMTDSQDWWPADFGHYGPLFIRMAWHSAGTYRTGDGRGGAGSGNQRFAPLNSWPDNVSLDKARRLIWPIKQKYGNKISWADLIILTGNVALESMGFKTLGFAGGRVDIWEPEADIYWGAEDKWLDDKRYSGERDLEDPLAAVQMGLIYVNPEGPNGDPDPFAAAVDIRETFARMAMNDEETVALIAGGHTFGKTHGAGDAALVGPEPEAASIEQQGLGWKSSYKSGKGGDAISSGLEVTWTSTPTQWSNNFFENLFGYEWELTKSPAGAHQWIPKNGAGKGVIPDAHDASKRHVPAMLTTDLALIFDPDYEKISRRFFEHPDEFADVFAKAWYKLTHRDMGPCTRYLGPEVPAEAFLWQDPIPAVDHPLVDEQDVTDLKLKIIGSGLTISEVVATAWASASTYRGSDMRGGANGARIRLAPQKDWPVNQPEQLAKVLKVLESIQSEFNKSGKKISLADLIVLAGCVGIDQAARNAGVEVTIPFTPGRMDATQAQTDVESFAVLEPVADGFRNYHPTQFSVSAEELLVDRAQLLTLTAPEMTVLIGGLRVLDTNADQSKTGVLTARPEFLTNDFFVNLLDMGTTWKPTSKAEDRFEGVDRVSGQPKWTASRVDLIFGSNSQLRALAEVYASSDAQLRFIDDFIAAWTKVMNLDRFDLRRA", "output": "Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity."}]}
+{"id": "function_test_1844", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLDILLTNIGQLLTMDQEDGVLRQEAMKTLPVIESGAVGIKDGVIMFVGTAEEAKGLQAREIIDCEGKVVSPGLVDPHTHLVFGGSRENEIALKLQGVPYLEILEQGGGILSTVNATKKASKEELVKKANFHLDRMLSFGVTTVEAKSGYGLDDETEWKQLEVVAQLQKEHPIDLVSTFLGAHAVPKEYKGKSKEFLQWMLDLLPAIKEKELAEFVDIFCETGVFSVEESKEFLLEAKELGFDVKIHADEIDPLGGAEAAAEIGAASADHLVGASDKGIEMLANSNTVATLLPGTTFYLNKESFARGRKMIDEGVAVALATDFNPGSCPTENIQLVMSIAMLKLKMTPEEVWNAVTVNSAYAINRGDVAGKIRVGRKADLVLWDAHHYAYVPYHYGVSHVNTVWKNGNLAYTRGDKAWSKATI", "output": "Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway."}]}
+{"id": "function_test_1845", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRLCDRDIEAWLDEGRLAITPRPPVERINGATVDVRLGNKFRTFRGHTAAYIDLSGPKDEVSAALDRVMSDEIVLNDGEAFFLHPGELALAVTYESVTLPADLVGWLDGRSSLARLGLMVHVTAHRIDPGWQGCIVLEFYNSGKLPLALRPGMLIGALSFEPLSGPAARPYNRRQDAKYRDQQGAVASRIDKD", "output": "Catalyzes the deamination of dCTP to dUTP."}]}
+{"id": "function_test_1846", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSAEKAKAYWQLMRMDRPIGSLLLLWPTVWALVIAAQGMPSWNVLIVFVLGVFLMRSAGCVINDFADRKVDGHVKRTKQRPLPSGKVTSKEAIGLFLVLGISSFLLVLTMNPLTIKLSFAGIFLAFIYPFMKRYTYLPQLFLGLAFSWAIPMAWAAQTGELPWIVWFVFVINALWTIAYDTQYAMVDRDDDLKIGIKSTAILFGRHDKLVIGVLQLVTLAMLVLLGQHYELGQSYYWTILVAASLFVYQQHLIRHRERDLCFKAFLNNNYVGIVIVIGLLIAFW", "output": "Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate."}]}
+{"id": "function_test_1847", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTLGDRLGLILIHPAVTTVPGLLEAKKLELSKKNYVIGDQFLINKLNDNSVTLEKDKYDLIYYLTPEKVEDIKFPVKLIPVIQSALKTNGSFYGLTEAFKVDALVNGFEIVSVEDNDYHWIKKAGSANANVVQLKTKKKLGNEVKSGKLPTFKSKLPTFKKKDAGNNEQVVKLSVEDVEDDLDDDPEVSNELLSKAKFFNSLSLNQDAEIDENNLIKSTDGDGITMITCGKTNTKKRRACKDCTCGMKELEEEEIDNIRTQQDKVVQFTSEELTEIDFTIEGKLVGGCGSCSLGDAFRCSGCPYLGLPAFKPGQPISLSSISDDL", "output": "Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2."}]}
+{"id": "function_test_1848", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSDNAQLSGLCDRFRGFYPVVIDVETAGFNAKTDALLEVAAITLKMDEQGWLMPDTTLHFHVEPFEGANLQPEALAFNGIDPSNPLRGAVSEYDALHAIFKMVRKGIKDSGCNRAIMVAHNATFDHSFMMAAAERASLKRNPFHPFVTFDTAALSGLALGQTVLSKACLAAGMEFDGTQAHSALYDTERTAVLFCEIVNRWKRLGGWPLPVPEEA", "output": "Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis."}]}
+{"id": "function_test_1849", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSQYRTFTAQDAVEYARTFGGIDDPSTLVEAQEVGDGNLNLVFKIFDTTGVSRIVVKQALPYVRCVGESWPLTLDRARLEAQTLVAHYQHCPQHTVKIHHFDPELAVMVMEDLSDHNIWRGELIKGAWYPQAARQLGEYLAQTLFHTSDFYLHPHDKKAQVATFINPEMCEITEDLFFNDPYQIHERNSYPAEIEGDVAALRSDAQLKLAVAALKHRFFSHAEALLHGDIHSGSIFVADGRLKAIDAEFGYFGPIGFDVGTAIGNLLLNFCGLPGHLGIRDAAAAREQRLTDIQELWNTFAERFQVLATEKTRDAALRAPGYASEFLKKVWADAIGFCGTELIRRSVGLSHVADIDTIQDAEMRHECLRHAITLGKALIVIADRIESVEALIARVRQYS", "output": "Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate."}]}
+{"id": "function_test_1850", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MALHDENVVWHAHAVTREDREALHGHKGAVVWFTGLSGSGKSTIAGALEEALHKLGISTWLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVDAGLVVLTAFISPHRAERQMVRERIGEGRFIEVFVDTPLATCEARDPKGLYKKARAGELRNFTGIDSVYETPESPEVHLDGEQLVTNLVAQLLDLLRQGDIIRS", "output": "Catalyzes the synthesis of activated sulfate."}]}
+{"id": "function_test_1851", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSLDISNYPVLAQANTPDELRQLPQAVLPQLADELRGFLLKSVGKSSGHFASGLGTVELTVALHYVYNTPFDRLIWDVGHQAYPHKILTGRRDKMHTIRQKGGIHPFPWREESEYDTFSVGHSGTSISAALAMAVAAEKEQAGRKVVSVIGDGAMTGGMVFEAMNHAGDLHNDMLVVLNDNEMSISENVGALNNHLAQLMSGRFYTTIRESSKKVLEGMPVIKEMAKRTEEHLKGMVVPGTMFEELGFNYIGPIDGHDVDALVETMRNMRNLSGPQILHIMTKKGRGYEPAEKDPIGWHAVPKFDPSTFEKPASKPSNPTFSQVFGKWLCDVAEKDDKVLGITPAMREGSGMVEFSQRFPKQYFDAAIAEQHAVTLGAGFACEGLKPVVAIYSTFLQRGYDQLIHDVALQKLPVLFAIDRGGIVGADGPTHQGAFDLSFMRTVPNMVIMAPSDENECRQMLYTGYCYREGPTAVRYPRGSATGEPQVEEMQALPIGKGLIKRQGQKVAILNFGTLLADVLTAAESIDATVADMRFVKPLDVELVKELASSHDLLVTVEENAIMGGAGSGVLELLQQLKQPMPVLQIGLPDEFIKHGASGEILAELRLDAAGILEQIEEYLK", "output": "Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)."}]}
+{"id": "function_test_1852", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLAKRIIPCLDVKDGQVVKGVQFRNHEIIGDIVPLAQRYAQEGADELVFYDITASSDGRVVDKSWVSRVAEVIDIPFCVAGGIKSPEDASQILSFGADKISINSPALADPTLISRLADRFGVQCIVVGIDTWFEAETGKYHVNQYTGDESRTRVTEWETLDWVKEVQKRGAGEIVLNMMNQDGVRNGYDLEQLRLVREVCKVPLIASGGAGTMEHFLEAFRDVDVDGALAASVFHKQIINIGDLKRFLSEQGVEIRLC", "output": "IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit."}]}
+{"id": "function_test_1853", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MFKGSMPALVTPMKDGAVDFATLEALVEWQIAEGSHGLVPVGTTGESPTLSHEEHEAVVAKVIEVAAGRVPVIAGAGSNNTVEAVRFVRHAKDAGADGALVVTPYYNKPTQGGMIAHYTALAEAADIPIVIYNIPGRSVVDMTPATMAALAALPTIVGVKDATGDLARVSQTRMACGPEFIQLSGEDATALGFNAHGGVGCISVTANVAPALCAQFQEATLAGDFATALALQDKLMPLHEAIFVEPGLVGAKYALSLLGKCSEDVRLPLLGLSDGTKVLIKDAMIHAGILG", "output": "Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA)."}]}
+{"id": "function_test_1854", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNVTETLNEGLKRGYSITVTAAELDAKVNEKLSEAQPEIEMKGFRKGKVPMALLKKQFGQKLLGEAMQETIDGAMAKHFEDSGDRPALQPEIKMTNEDWKEGDDIEVAMSYEALPEVPDTDFSTVTLEKLVVKADEEAVNEALQNLAENAKSFETKEGAAEDGDQVVIDFLGKVDGEAFEGGAAEDYPLVLGSNSFIPGFEEQLIGTSAGEEKNVDVSFPEQYQAEHLAGKAAVFECKIKEVKAPKAAEIDDEMAKQFGAEDLETLKGQISERLEAEYAGAARAVMKRKLLDELDTLVKFELPPSLVATEAGQIAHQLWHEENPEVEGHDHPEIEPTEEHNKLAERRVRLGLLLAELGQKNEIQVTDAEMTQAIMAQARQYPGQERQFFEFIQQNQQMQQQLRAPIFEDKVVDYIFELATVTEKEISKDDLQKAVEALDDEV", "output": "Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase."}]}
+{"id": "function_test_1855", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKHAIHHIHFVGIGGAGMSGIAEVLHNLGYAISGSDLSDSATLRRLAGLGIATHVGHAAAHIEGADAVVTSTAVQSDNPEVLAARERKIPVVPRALMLAELMRFKQGIAIAGAHGKTTTTSLVTSVLAEAGLDPTFVIGGKLNSAGANAKLGQGDYIVVEADESDASFLNLLPVMAVVTNIDADHMETYGHDFGRLKGAFVDFLHRMPFYGRAIVCVDSPAVREILPQVARPVTTYGFAEDAQVRALNVRAEAGSMHFTVRRSNGQSYPDLDVVLSLPGEHNVLNALSAVAVAMELEISDDALLRAFESFKGVGRRFQRYGELAAADGGSFTVIDDYGHHPVEMAATLAAARGAFPGRRLVLAFQPHRYSRTRDCFEDFVKVIGLADAVLLTEVYAAGEAPVVAADGRSLARALRVAGRVEPVFVENVAELPAAIAVNARDGDVLLCMGAGSIGAVPGKLVEMLQKQELQAQQGAAQ", "output": "Cell wall formation."}]}
+{"id": "function_test_1856", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEAPVTPYIWQYQPETGTAAGARQNYGAVINWLSSDNNMYHRVQEVNRQRNKIDDFREQTVRADMAHSFNDWKPQQLSQPASTAYLPAPNPIAGPRTIPDVIFTAEGEQLAGASPSLLSGGASLPPSSYRLGDGREYRKFTRDAMPFPHNWLVKENGVWVPVEERDPLLSEEGRNALSSYPTLTYAQPPILRYRRLGQQLQGGGVVAPSSRVVSLLTEQPRMPRTEGMTPYQFSAEFPPVVYDHPFSRNLTLFPKEFSPLFDPKDQVLATSLATLQYR", "output": "[Hexon-linking protein-N]: Structural component of the virion that acts as a cement protein on the capsid interior and which glue the peripentonal hexons and group-of-nine hexons together.; "}]}
+{"id": "function_test_1857", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIKWLTRPADYAPVWQDMRAFTAGRGAATPDEVWLCEHAPVYTLGQAGKPEHLLNPGAIPVVMCDRGGQVTYHGPGQVVAYTLFDLRRAGLFVREYVRLLEDAAIGTLDDFGVPGACRKPGAPGVYVPLGPAGELAKIAALGIKIRNGYAYHGVALNVDMDLSPFLGINPCGYEGLVTVDMAACGVRRDLVDVGQRLAERLLAAMPEPAGATR", "output": "Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate."}]}
+{"id": "function_test_1858", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEVPAKIQKRIERLRQEINDHNYRYYVLSQPTIPDSVYDELFHELQKLEKKYPETITPSSPTQRVGAEPLKVFEPVHHEIPMLSLDNVFDEKGLRAFDKRIRQRLKLDKPFEYVCEPKMDGVALSLLYENGELIRAATRGDGYTGENVTQNTRTIASVPLQLRGNDYPELVEIRGEVLMPREGFAKFNREAEKRGDKTFANPRNAASGSLRQLDPRITAKRPLIFYGYLIGLLKGKDFPKNHCDVLKWFKDWGIPVISEIKVVGGIEGCLDYYEHLVKTREKMPFDIDGIVIKVNSLQVQAELGFVSRAPRWAIAYKFPAQEKMTVVKAIEFQVGRTGVVTPVARLEPVSVSGVTVSNATLHNFDELYRKDVRVGDTVIVRRAGDVIPEVVGPILAKRPKKAKLIKIPSRCPVCHAEVIKPEGEAVARCVGGLYCRAQLRESIKHFASRRALDIEGLGDKLVELFIQEKLIKDITGIYQLKKSAITALPRMGEKSAENLLTAIEKSKKTTLPRFLYALGIRGVGDTIARTLARHFHELDLLMKASIETLQEIRDIGPVVAENIHAFFHQKHNAELINKLIHLGVHWPQEKAVVKSEIAGKTFVLTGALKSLTREEAEEKIERSGGKATSSVSKNTDYVIVGENPGSKYEKAKALGISLIDEEAFLKLLKS", "output": "DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA."}]}
+{"id": "function_test_1859", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSEKHPGPLVVEGKLSDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAAQKLEPRHAMLLRCRLPGGVITTTQWQAIDKFAADNTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSNPYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGLETFKAEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDNNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHQGEFRITANQNLIIASVPESQKAKIEKLARDHGLMNAVSAQRENSMACVSFPTCPLAMAEAERFLPSFTDKVEAILEKHGIPDEHIVMRVTGCPNGCGRAMLAELGLVGKAPGRYNVHLGGNRMGTRIPRMYRENITESEILDSVDELVGRWAKEREAGEGFGDFTVRAGIIRPVLDPARDFWE", "output": "Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate."}]}
+{"id": "function_test_1860", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPIKSDKWIRRMAESHQLIYPFEPKQVRETPSGKVISYGTSSYGYDVRCADEFKIFTNINASIVDPKNFDPNGFIDLKANVCIIPPNSFVLARTVEYFKIPRNILTICLGKSTYARCGIIVNVTPLEPEWEGHVTLEFSNTTNLPAKIYANEGVAQMLFLESDEVCDISYKDRGGKYQGQKGVTLPVA", "output": "Catalyzes the deamination of dCTP to dUTP."}]}
+{"id": "function_test_1861", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIALIQRALSASVVVEGNIVGEIGPGLLVLLGVEQGDTEQKAQRLCERVLGYRIFSDENDKMNLNVQQAGGSVLVVSQFTLVADTQKGMRPSFSRGAIPQEADRLYQYFVAQCRERGVKTETGLFAADMKVSLVNDGPVTFWLQV", "output": "An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality."}]}
+{"id": "function_test_1862", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKLLHVDGSILGPHSVSRTVSAAIVDRLRAQHPGLDVIYRDLAGTPLPHLSGAVLAGAQPNATNTPDVQHDVELGRQVLEEFLAAEIVVIGAPLYNFTLSSQLKAWIDRILVAGVTFRYGPSGAEGLAGGKRVIAVVSRGGLYGPGTPAAAAEHAETYLRTVLAFIGITAPEVIVAEGIALGPEARERALAGALDAAAALKAA", "output": "Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.; "}]}
+{"id": "function_test_1863", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAASPLVRFAPSPTGFLHIGNARPALLNALFARREGGRFLLRLDDTDRERSTEEFATAAAEDLGWLGIEPDLFFRQSDRTALYDTAAERLKAAGRLYPCYETPEELDRRRKRQLGRGLPPIYDRAALSLTEAERAAFEADGRQPHWRFKLDHRVVAWNDLVRGESHVDCASLSDPVLVRADGSYLYTLPSVVDDAEVGVTHVIRGEDHVTNTGVQVQLFEALAAAVPAFGHHNLLTTADGEGLSKRLGHLSLRSLREAGYEPAAVRSLAVLTGSAEAVRPIASLDELAGLVDLAHLSRAPARFDPAELDGMNARLVHDMPLEAVHERLAALGVPAEAAEAFWLAVRANLGRVSDAAAWWQVVNGPVTPVIAEPDFIARAADLLPEAPFGPGTWKAWTDAVKAETGAKGRALFMPLRLALTGLDHGPDLAALLPLIGRERAVRRLAGETA", "output": "Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)."}]}
+{"id": "function_test_1864", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTELFYDDDADLSIIQGRTVAVIGYGSQGHAHALSLRDSGVDVRVGLAEGSQSRAKAEAEGLRVLNVAEAVAEADVIMVLTPDQVQRHVYAESIAANLQAGDALFFGHGFNIRYGYIQPPADVDVALVAPKGPGHIVRREFEAGRGVPDLIAVEQDPSGNAWALALSYAKAIGGTRAGVIKTTFTEETETDLFGEQAVLCGGASQLIQYGFETLTEAGYKPEVAYFEVLHELKLIVDLMVEGGIAKQRWSVSDTAEYGDYVSGPLVIDAHVKDNMKAVLKDIQDGTFAKRFIDDQDAGAPEFKALRAKGEQHPIETTGRELRKLFSWIQNDDDYTEGSVAR", "output": "Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate."}]}
+{"id": "function_test_1865", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MARSSIEQLTSFLRSVNGRAKKALSQNFLVDGNILRKILTTAEVQPGDWVLEIGPGFGALSEVLLSQGANVIALEKDPMFEESLSQLPMDIEITDACKYPLTSLEDKGWKGKGRIVANLPYHITTPLLTKFFLECPYRWKTVTVMIQDEVARRITAKPGDKDYGSLTVFLSFFADVQYAFKVSPNCFYPKPSVHSAVVHMRVHEQFALADSEIEEFFTLTRAAFGQRRKLLANSLKNLYPKDKVFQVLEQLGFSEKTRPETIFLEEYLKIFHLLKDI", "output": "Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits."}]}
+{"id": "function_test_1866", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSEKNLLTALSKMITEQRNPNSMNIDQLSALELVKVINQEDKQVPLAVEKCLAQIAQAVEKIVQAFQNGGRLVYIGAGTSGRLGVLDASECPPTYGVSSEMVVGIIAGGERALRHPIEGAEDNTEQGKADLQAVNFSQKDVLVGIAASGRTPYVIGALEYAKSLGATTVSIASNPNSAMAQIAEIAIDTIVGPEVLTGSSRMKSGTAQKLVLNMLTTASMVMIGKCYSNLMVNVQASNEKLKARAIKIVMEATECDRTVAENTLKIAENNAKLAIMMILSDSDKTTAEQLLAAHHGKLRQALAK", "output": "Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling."}]}
+{"id": "function_test_1867", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAAHYLDFERPIADLESKIEELSKLSETAGPGAFESEIQALRDRAQQMRKEAYAGLDAWQKTMVARHPERPHLKDYIAGLIDEFVELRGDRKFADDQAIVGGLGRFRGVPVVVMGHEKGHDTTTRLKHNFGMARPEGYRKAVRLMDMAERFNLPVITFVDTAGAYPGLGAEERGQAEAIARSTERGLVLGTPMVATIVGEGGSGGAIALAGANKVLILEHSIYSVISPEGAASILWRDGARAKDAAANMKITAQDLIQLKIVDRIVEEPAGGAHSDPDAAIQSVGDAVEDELKALMKLSAAELKKQRAARFYAIGREGLQ", "output": "Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA."}]}
+{"id": "function_test_1868", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPVKIPDDLPAAEILESENIFVMSETRAANQDIRPMKVLILNLMPNKIETETQLLRLLGNTPLQVDVDLLRIHDKASKHTSIDHMNNFYRDFEQVRQKNYDGLIITGAPLGQIEFEEVLYWDHIREIIDWSQQHVTSVLFLCWAAHAALYHLFGLNRSLLTTKRSGVFTHKRTSEHYPLLRGFDDEFFAPHSRFAEMDIDKLKAHPELQVLTESETAGAYMVLCKNNRNLFVMGHPEYQKSTLKDEYYRDLEQGLAPEVPQNYFTNNDPLQAPIARWHSHGSLLVSNWLNYYVYQLTPYNLDDMTGITPWGT", "output": "Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine."}]}
+{"id": "function_test_1869", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLTRKQLDLLRFIQQRMRETGVPPSFDEMKDALDLKSKSGIHRLITALEERGFLRRLPNRARAIEVIRIPEAVASGPAEVVRFTPSVVEGGRSSAPVKPAPLPTALVSDESGHAVSIPVMGRIAAGTPISAIQSQSRSVAMSPDFLAGGEHYALEVRGDSMIEAGILDGDLVVIRRQDTANTGDIVVALIDDEEATLKRLRRRGSSIALEAANPAYETRVLGPDRVRIQGRLVSLIRKY", "output": "Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair."}]}
+{"id": "function_test_1870", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRCPSLARLPNRALSGLTRSPVRLQSQNFLYQRCASTAALRSPIAGPAYQSVFHRHNLQRRNASAATTAAVLEAAASNPDGLSQEAIIDNLDPAEAIRLSRLRNIGIAAHIDSGKTTCTERVLFYTGRIKAIHEVRGRDNVGAKMDSMDLEREKGITIQSAATFCDWIKKGDDGKEEKYHINLIDTPGHIDFTIEVERALRVLDGAVMILCAVSGVQSQTITVDRQMRRYNVPRISFVNKMDRMGANPFKAVEQINTKLKIPAAAVQVPIGAEDEFEGVVDLIRMKSIYNDGPNGETVVVKDEIPEKVKSVVEERRRMLIETLADVDDEIAELFLEETEPTEQQLKAAIRRATIGLKFTPVFMGSALANKSVQPMLDGVIDYLPNPSEVENLALDRKRDEASVKLVPYNSQPFVGLAFKLEESNFGQLTYIRVYQGTLRKGANVFNARNNKKVKVPRIVRMHSNEMEEVSEIGAGEICAVFGVDCASGDTFTDGQLGYTMTSMFVPEPVISLSIKPKNSKDSANFSKAMARFQREDPTFRVSYNAESEETLISGMGELHLDIYIERMRREYRVDCVTGPPQVAYRETIGNRVEFDHLLKKQSGGPGEYARVVGWMEPTGKLEDNKFEEQIVGGSISEKFLFACEKGFNLACEKGPLIGHKVLGTKMVINDGATHMTDSSEMSFKNATQQAFRKAFMESNPSVLEPMMKIAVTAPGEFQGDVISLLNKRNATINDTETGVDEFTVYADCSLNGMFGFSTHLRAATQGKGEFTMEFSHYEKAQPQLQKELIQKYLKAQADRHKK", "output": "Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome."}]}
+{"id": "function_test_1871", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQAVIQTGPGTLQLTENVPKPSVEPGSRKVLVKVHAVALNHSDWKMVDFSAKPGAISGYDMAGVLEAIDDSMNSDLAVGDRVLGVTSIHGGAFAEYVVTDGDLLVKIPENMDFQHAASYGVGIVTTGLALYGNECLALNWPNTDGTGSAAPQKTRVGPRGWSGGDALTDNDNETPRIPVLVYGASTSTGTLAIQLLKLSGYEPIAVCSPHNFGLVQSRGASKCFDYHSQGCGAMIKQYTYNRLEYALDCITTASSMRLCYEAIGATGGKYVSLDPFNARVQRSRADVKPFFCYALTIFGLPIELSGEFARGAKPEDRKLAEKFVKIAEKLIEKGRLKAHPTMLKSGGLGGIASSIDLLRKGKVSGSKLVFDVVGN", "output": "Trans-enoyl reductase; part of the gene cluster A that mediates the biosynthesis of botcinic acid and its botcinin derivatives, acetate-derived polyketides that contribute to virulence when combined with the sesquiterpene botrydial . Botcinic acid and its derivatives have been shown to induce chlorosis and necrosis during host plant infection, but also have antifungal activities . Two polyketide synthases, BOA6 and BOA9, are involved in the biosynthesis of botcinins. BOA6 mediates the formation of the per-methylated tetraketide core by condensation of four units of malonyl-CoA with one unit of acetyl-CoA, which would be methylated in activated methylene groups to yield a bicyclic acid intermediate that could then either be converted to botrylactone derivatives or lose the starter acetate unit through a retro-Claisen type C-C bond cleavage to yield botcinin derivatives . The second polyketide synthase, BOA9, is probably required for the biosynthesis of the tetraketide side chain of botcinins (Probable). The methyltransferase (MT) domain within BOA6 is probably responsible for the incorporation of four methyl groups (Probable). The trans-enoyl reductase BOA5 might take over the enoyl reductase function of BOA6 that misses an ER domain (Probable). The monooxygenases BOA2, BOA3 and BOA4 might be involved in further hydroxylations at C4, C5 and C8, whereas BOA7, close to BOA9, could potentially be involved in the hydroxylation at C4 in the side chain of botcinins (Probable)."}]}
+{"id": "function_test_1872", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTPEHLPTEQYEAQLAEKVVRLQSMMAPFSDLVPEVFRSPVSHYRMRAEFRIWHDGDDLYHIIFDQQTKSRIRVDSFPAASELINQLMTAMIAGVRNNPVLRHKLFQIDYLTTLSNQAVVSLLYHKKLDDEWRQEAEALRDALRAQNLNVHLIGRATKTKIELDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALDVTKGSKGDLLELYCGNGNFSLALARNFDRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNGVREFNRLQGIDLKSYQCETIFVDPPRSGLDGETEKMVQAYPRILYISCNPETLCKNLETLSQTHKVERLALFDQFPYTHHMECGVLLTAK", "output": "Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA)."}]}
+{"id": "function_test_1873", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKITKITTYRLPPRWMFLKIETDEGVVGWGEPVIEGRARTVEAAVHELGDYLIGQDPSRINDLWQVMYRAGFYRGGPILMSAIAGIDQALWDIKGKVLNSPVWQLMGGLVRDKIKAYSWVGGDRPANVIDGIKILREIGFDTFKLNGCEELGLIDNSRAVDAAVNTVAQIREAFGNQIEFGLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAEYYPKLAAQTHIPLAAGERMFSRFDFKRVLEAGGISILQPDLSHAGGITECYKIAGMAEAYDVTLAPHCPLGPIALAACLHIDFVSYNAVLQEQSMGIHYNKGAELLDFVKNKEDFSMVGGFFKPLTKPGLGVEIDEAKVIEFSKNAPDWRNPLWRHEDNSVAEW", "output": "Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy-D-galactonate."}]}
+{"id": "function_test_1874", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSPVTGEETPAEQQGTADNPVYVRRIMGLETEYGITNVLDGTRRLGPDEVSRLLFSPIVEKYRSSNIFTENASRLYLDVGAHPEIATAECDSLHQLLAYDRAGDELVQQLASRAEEELASNGIGGNVFLLKNNTDSMGNSYGCHENYLISRNVLLKHLSSQLLPFLVTRQLICGAGKLTIPSPGAPNENFEAGFMMSQRADYMWEGISSATTRSRPIINTRDEPHADSSKYRRLHVIVGDSNMSETTTALKIGSALLVLEMIEAGAELPNYELANEIRAIRDIARDFTGLTEVKLRSGETATPLEIQRTFHAAAVHWLEHRPEPECVDGRWLGTPREQLAPVVELWGRVLDCFETGDFSPVDTEIDWVIKKKLLHGMASRHGLEMTDPRLAQIDLRYHDIHPARGLFNVLKRRGQAASILGEEQIREAMDQAPATTRAALRGRFLTAAREHGCATTVDWMRLKINGEFGSEVALPNPFAATDPQVDEMIASMADLGDTDATARG", "output": "Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine."}]}
+{"id": "function_test_1875", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPALVLLGAQWGDEGKGKATDLLGGSVDYVVRYQGGNNAGHTVVVGDQKYALHLLPSGILSPGCTPVIGNGVVVDPAVLLSELSGLNERGVDTSKLLISGNAHLITPYNVTLDKVTERFLGKRKIGTTGRGIGPTYADKINRVGIRVQDLYDESILEQKVEAALEQKNQLLAKVFNRRAIEAGKVVEDMLQYAEQIKPFVADTTLILNDAIDEGKVVLFEGGQGTLLDVDHGTYPFVTSSNPTAGGACTGAGVGPTKISRVIGILKAYTTRVGAGPFPTELHDEDGEALRRIGGERGVTTGRDRRCGWFDAPIARYATRVNGLTDFFLTKLDVLTGWERIPVCVAYEIDGKRVEELPYNQTDFHHAKPIYENLPGWSEDITKAKTFSDLPKNAQAYVKALEEMSGAPISAIGVGPGRTETIEINSFL", "output": "Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP."}]}
+{"id": "function_test_1876", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAIKRNQGSNPKPEKKERLTKAETHQEQDNLEESIRPHSFDEYIGQKDLKDVLSIVIEAAKTRNEPMDHLLLYGPPGLGKTTISLILASAMGVNCKITAAPALERPRDITGLLVSLKPGDILFIDEIHRLNRLTEELLYPAMEDYRLEITIGKGQAARTRSIPLPKFTLVGATTKVGSLTSPLRDRFGLIQRLKFYEPEELALIIKRTAKLLNTSITEQGAAEIGRRSRGTPRIANRLLRRVRDYIQVKKFDSITQELAAEALDIYQVDPQGLDWTDRLILDTMITQFNGGPVGLEAVAAATGEDAKTIEEVYEPYLLQIGYLNRTPRGRVVTTVAYQHLGKTGEEQLSIFSEQ", "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA."}]}
+{"id": "function_test_1877", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKNWPRLAFIAWVLLRQGMDQLVLSHMPHASLRLLARLMSIGRTHHEPRGVRLRMALERLGPIFVKFGQVLSTRRDLIPHDIANELAKLQDRVPPFPSDVSRAAVVQSLGRPIEEVFASFDADPVASASIAQVHFGVLHDGREVAVKVLRPNVLNIIEADLALLRVAAAWLERLSPDGRRLRPREVVAEFDNYLHDELDLGREAANAAQLRRNMGGLDLIMLPEMIWDLSSAEVLVMERMHGVPISQIETLRAAGIDIPKLARDGVTIFFTQVFRDGFFHADMHPGNIMVSTAPATFGRYIALDFGIVGTLDSRDKEYLAQNFLAFFRRDYRRVAELHIESGWVPASTRVDELEGAVRAVCEPHFDRPLKDISLGQVLLRLFQTSRRFNVEIQPQLVLLQKTLLNVEGLGRQLDPELDLWQTAKPFLERWMNEQVGWRALLGSIKDEAPRYAKLLPELPRLLHDALQAHARPQRPSDELLLALLHEQRRTNRLLLTVFYLIGGFVAGGLFAHWILPGLLHLL", "output": "Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis."}]}
+{"id": "function_test_1878", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSEVEEVLKEAYKLVTPTPEEERKVAEVGSRVRQWVSEALAGVAAEVDMYGSSARSTWLPGQRDIDIFVVLRDRSIKPEDVVQTLSRYFDGVGVPWSLRYAQHPYLSLYVEGYEVDVVPCYKIAPGERPITAADRSPLHHKFLSERLSEDQRRDVRLLKLFLKSIGVYGAEIKVEGFSGYLTELLVAYYGSFVDVLKAASGWRPYRTYISFTESKTKFKAPLVVVDPVDPNRNVAAAVSLTSMSTFVLASRRFLKKPSLSYFSPPEAPALGVNAVEVVFPYPGESPDVVWGRYKRLGKSLYKHLRECGFKIYRWGVESDEKTYVSIIYVVEDVELPPYVLHRGPPVYDNAIDAFVEKYLREEVVGPFVLGTRAYVIKRRRYTNIGDCIRAKLGGGYAIRINQYGGGLVRKTPWLT", "output": "Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate."}]}
+{"id": "function_test_1879", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTWSQDLAHKTYSIRHWADGYFEVNDAGHMVVMPLGGDGVRISLPEVVDAARAAGAKLPLLLRFPDILGHRLGKLQAAFAQAQSEWEYAGGYTAVYPIKVNQHRGVAGVLASHQGDGFGLEAGSKPELMAVLALSRPGGLIVCNGYKDREYIRLALIGRKLGLKTFIVIEKPSELRMVLEEAKTLDVLPGLGVRVRLASLGAGKWQNSGGDKAKFGLSPRQVLDVWKVLRGTEYADCLNVMHFHMGSQISNVRDIAKGMREATRYFVELSRLGAKITHVDVGGGLGIDYEGTRSRSDCSINYGLQAYASHIVQPLASACEDYDLVPPRIVTECGRAMTAHHAVLIANVTEVEAVPEGRVPGVCDDEPAVVRHMREIYGELDARPAIELFYEAQHFHAEGLAAYTLGQIDLVHRARIDDLFYAISHGVRERLSHEEKSHRPVLDELNERLVDKYFVNFSVFESIPDVWAINQIFPIVPIERLNEVPTRRGVVCDLTCDSDGTVKQYVENESLDSALPLHVLRHGEAYRIGFFLVGAYQEILGDIHNLFGDTDAVEVAVDGRGYRIAQQRCGDTTDVMLDYVGYALDEVRRVYAQRIAAAGMSAAESKALSDMLEAGLTGYPYLSDVPLE", "output": "Catalyzes the biosynthesis of agmatine from arginine."}]}
+{"id": "function_test_1880", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPELPEVETVRRGLAPVMVGASFTTVEQRRADLRFPFPDNFAARLEGRRVEALGRRAKYLLADLDDAQVLVMHLGMSGSFRIEKAGDLASPPPGKNAAHDHVVFGLSTGTRIIYNDPRRFGFMHLIARQDLAGHPLFRNVGIEPLGNELEGALLARLFAGKTTPLKTALLDQTLIAGLGNIYVCEALHRAGLSPRRAAGTLAGKKGQPTERAHRLSEIIRAVLEEAIEAGGSSLRDHRQADGALGYFQHRFRVYDREAEPCPREGCGGTIKRIVQAGRSTFFCAKCQR", "output": "Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates."}]}
+{"id": "function_test_1881", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTNSIEQAWDLAKQRFAAVGVDVDAALTRLDTLPVSMHCWQGDDVTGFEDPDGVLTGGIQATGNYPGKARNATELRSDLELALALIPGPKRLNLHAIYLESDTSVARNKIEPRHFSHWVAWAKKHQLGLDFNPSCFSHPLSADGFTLSHADPEIRQFWIEHCQASRRISAYFGEQLGTPSVMNIWIPDGMKDTPIDRLAPRQRLLSALDEVISEKLNPAHHIDAVESKLFGIGAESYTVGSNEFYMGYAASRQTALCLDAGHFHPTEVISDKISSAMLYVPRLLLHVSRPVRWDSDHVVLLDDETQAIASEIIRHNLFDRVHIGLDFFDASINRIAAWVIGTRNMKKALLRALLEPTDMLRQLELRGDYTARLALLEEQKSLPWQAIWEGYCQRNDVPVDARWLDAVREYEQQILSQR", "output": "Catalyzes the interconversion of L-rhamnose and L-rhamnulose."}]}
+{"id": "function_test_1882", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSDDTTQIEPAMAQETSPRANTRKVFVKTYGCQMNVYDSQRMADSLAAEGYVATDTPDDADLVLLNTCHIREKASEKLYSALGRLRKMRDARAADGKELTIGVAGCVAQAEGQEILRRAPNVDLVIGPQTYHRLPNALARVRGGEKVVETDYAIEDKFEHLPAPRREETRKRGVSAFLTVQEGCDKFCTFCVVPYTRGSEVSRSVKQIVAEAERLADSGVRELTLLGQNVNAWHGEGEDGREWGLGELLFRLARIPGIARLRYTTSHPRDMDDSLIAAHRDLRQLMPYLHLPVQSGSDRILKAMNRRHKADEYLRLIERIRNVRPDMALSGDFIVGFPGETDQDFEDTMQLVRDVNYAQAYSFKYSPRPGTPGADLDDHVEEAVKDERLQRLQALLSAQQYAFQDSMIGRKMDVLLEKPGREAGQMVGRSPWLLPVIIDDNKDRVGDIIHVKIVSTGTNSLIAQKLA", "output": "Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine."}]}
+{"id": "function_test_1883", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRNIKLIIEFDGTNFCGWQRQIKDRTVQGCLEKAILKITGEKSLTNGSSRTDGGVHAKAMVANFITNSSIPGEKFREALNTKLPDDIAVIKSEEVDMDFHARYSSKGKMYSYTIVNRYEKLSFGKQYVHHVRKELNVEDMKKACECFIGKHDFKAFMSPGSSAKTTVRTIQEFYIEKNEDVIKIFISADGFLYNMVRIIVGTLINIGTGKTKLEDVDNIINDGIRKRSGMCVPPNGLVLEKVFY", "output": "Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs."}]}
+{"id": "function_test_1884", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSAIWIAIAVLSALSLVFGGLLGYASRRFAVEEDPIVEQIDAILPQSQCGQCGYPGCRPYADAVGNNGEMINKCAPGGEQTMLKLAALLNVEPQPLGAEEAREPERKVAWIDEANCIGCTKCIQACPVDAIVGATRAMHTVLSDICTGCDLCVAPCPTDCIEMRPVATTTANWKWDLHTIPVRVITVESHA", "output": "Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane."}]}
+{"id": "function_test_1885", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTQVAKKILVTCALPYANGSIHLGHMLEHIQADIWVRYQRMRGNQVYFICADDAHGTPIMLKAQQMGVAPEQMIADMSQEHQTDFAGFNISYDNYHSTHSEENRELSELIYTRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPNCKSPDQYGDNCEVCSATYSPTELIEPKSVVSGATPVLRDSEHFFFDLPEFSAMLQAWTRSGALQEQVANKMQEWFDSGLQQWDISRDAPYFGFEIPGAPGKYFYVWLDAPIGYMGSFKNLCDKRGDIDFDAFWQKDSDAELYHFIGKDIVYFHSLFWPAMLEGSQFRKPTNLFVHGYVTVNGAKMSKSRGTFIKASTWLQHLDADSLRYYYAAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGFINKRFAGQLSAELADPALYQTFIDASTSIAQAWSSREFSRAVREIMALADAANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTWLKPVMPSLAERAEAFLNQPLTWDGIEQPLLNHNIAAFKALYNRIEMDKVNGLIAASKEDTAAAQPAVTGPLADDPLQETISFDDFAKVDMRIALIENAELVDGSDKLLRLTLDIGGEKRNVFSGIRAAYPDPALLVGRLTVMVANLAPRKMRFGLSEGMVMAAGPGGKDIFLLSPDSGAQPGQQVK", "output": "Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation."}]}
+{"id": "function_test_1886", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSLVLAVYGKGGIGKSTTSANISAALALKGAKVLQIGCDPKHDSTFPITGKLQKTVIEALEEVDFHHEELSPEDIVETGFAGIDGLEAGGPPAGSGCGGYVVGESVTLLQEMGLYDKYDVILFDVLGDVVCGGFSAPLNYADYAVIIATNDFDSIFAANRLCMAIQQKSVRYKVQLAGIVANRVDYTKGGGTNMLDQFAEQVGTRLLAKVPYHELIRKSRFAGKTLFAMDENEPELADCLAPYNEIAEQILSKTPIASVPKPIGDREIFDIVGGWQ", "output": "Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP."}]}
+{"id": "function_test_1887", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTDLDFIDVADLRREYMKGGLRRHELTEQPLVLFEKWLKQACEARLSDPTAMCVATVDENGQPYQRIVLLKHFDEKGLVFYTNLGSRKASHLEHNQRVSLLFPWYPLERQVCFLGKAEKLSAFEVVKYFHSRPKDSQIAAWASKQSSRISARGVLESKFLELKQKFQHGEVPLPSFWGGYRVTFDSVEFWQGRENRLHDRFIYQKSPEGWSIERLAP", "output": "Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)."}]}
+{"id": "function_test_1888", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRHPLVMGNWKLNGSIHMVHELIAALRKEISGVAGCDVAIAPPTVYLCQARHEIGGSRIALGAQDTGVNLSGAFTGETSPEMLKNVDVKYVIIGHSERRTYHKESDEFIAQKFGVLKELGLTPVLCIGETEAENEAGKTQEVCARQIDAILNAHGAQAFKDAVIAYEPIWAIGTGKSATPAQAQAVHKFIRDHIAKQDAAIAEQVIIQYGGSVNDKNAAELFSQPDIDGALVGGASLKADAFAVIVKAAAEAKAKK", "output": "Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)."}]}
+{"id": "function_test_1889", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKIVEVRHPLVQHKIGLMRNAALSTKDFRELANELGTLLAYEATADLETEPHTLPGWAGPITVQRIAGAKITVVPILRAGLGMLSGVLSLIPAARVSVVGLQRDEETLQPVPYFERLTGRLEERDALILDPMLATGGTLIATIDMLKRAGARRIKGIFLVAAPEGIEAVKAVHPDVEIYTAAIDAQLNDKGYILPGLGDAGDRIFGTRVG", "output": "Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate."}]}
+{"id": "function_test_1890", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKILVDENMPYARELFSRLGEVKAVPGRPIPVEELNHADALMVRSVTKVNESLLSGTPINFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSALLMLAERDGFSLRDRTIGIVGVGNVGSRLQTRLEALGIRTLLCDPPRAARGDEGDFRTLDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGAILINACRGPVVDNAALLARLNAGQPLSVVLDVWEGEPDLNVALLEAVDIGTSHIAGYTLEGKARGTTQVFEAYSAFIGREQRVALETLLPAPEFGRITLHGPLDQPTLKRLAHLVYDVRRDDAPLRKVAGIPGEFDKLRKNYLERREWSSLYVMCDDETAAALLCKLGFNAVHHPAH", "output": "Catalyzes the oxidation of erythronate-4-phosphate to 3-hydroxy-2-oxo-4-phosphonooxybutanoate."}]}
+{"id": "function_test_1891", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSWQQRVDDALTARRVTDTLRRRYVVSQGAGRWLVANGRQYLNFSSNDYLGLSQHPQIIRAWQQAATRFGVGSGGSGHISGYSVAHQALEEELAQWLGYPRALLFISGFAANQAVITALMKKNDRIVADRLSHASLLEAANLSPAQLRRFIHNDTQHLSRLLQSPCVGQQLVVTEGVYSMDGDSAPLAEIQHIARRHHAWLLVDDAHGIGVTGDEGRGTCWQRGVKPELLVVTFGKGFGVSGAAVLCSESVADYLLQFARHLVYSTSMPPAQAQALSASLAVIRSDEGGERREKLAALVQRFRAGVNASRFTLLNAHSAIQPLIVGDNSRALRLAEALRQQGCWATAIRPPTVPVGTARLRLTLTQAHEACDIDRLLEVLHGAGE", "output": "Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide."}]}
+{"id": "function_test_1892", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MHEAQIRVAIVGAGGRMGRQLIQAAMAMEGVQLGAALEREGSSLLGSDAGELAGVGKTGVIIQSDLASVKDDFDVLVDFTRPEGTLAHLAFCRKHGKGMVIGTTGFDDAGKQAIREASQEIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIAGALDKDLKDCAVYSREGYTGERVPGTIGFATVRAGDIVGEHTAMFADIGERVEITHKASSRMTFANGALRSALWLKTKKNGLFDMRDVLGLDVL", "output": "Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate."}]}
+{"id": "function_test_1893", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKLRTKAKALRGRLRVPGDKSISHRAVIFGAIAEGQTVIHGLLRGQDVLATIQAFRDLGVTIYESADSLIIEGRGFKGLKPAQKPLDMGNSGTSMRLLAGLLAAQDFSVQLFGDDSLSRRPMDRITIPLSLMGAELSGQGEKELPPLIVKGCQGLRPIHYQLPVASAQVKSAILLAALQTQGETVILEKELTRNHTEEMIEQFGGKLSVAGKQISIKGPQRLQGQTLQIPGDLSSAAFWLAAGLIVPGSDLVLENVGINPTRTGLLEVIEKMGGQLSYQAVDKDIQTATLKVSYSTLKGIEISGDLIPRLIDELPVIALLATQAQGTTYIRDAQELRVKETDRIQAVTDVLGQMGADIQATEDGMVIRGKTPLHGAAVSTCGDHRIGMMTAIAALLVEEGQVTLERAEAILTSYPDFFKDLERLWHD", "output": "Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate."}]}
+{"id": "function_test_1894", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MREERPIIALDFPSFEEVKSFLSLFPADERLYVKIGMELYYAEGPDIVRYVKSLGHSVFLDLKLHDIPNTVKSTMAVLSRLGIDMTTVQAAGGVEMLRAAREGLGQGPILIAVTQLTSTSEEQMREDQNIQSTLLASVLHYAKRTAQAKLDGVVCSAHEVKAIKSEVPAGFVCLTPGIRPTGADIGDQKRVMTPHQARAIGSDYIVLGRPITQATDPVKAYHQIKAEWNR", "output": "Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP)."}]}
+{"id": "function_test_1895", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRQLLPGDTVWRNIRLATMDPQRQAPYGLVDNQALIVREGHICDIVPETQLPVSGDNIHDMQGRLVTPGLIDCHTHLVFAGNRAAEWEQRLNGASYQHISAQGGGINATVSATRACAEEPLYLLARERMMRLASEGVTLLEIKSGYGLELATEEKLLRVAAKLAAENAIDISPTLLAAHATPAEYRDDPDGYITLVCETMIPQLWQKGLFDAVDLFCESVGFNVAQSERVLQTAKALGIPVKGHVEQLSLLGGAQLLSRYQGLSADHIEYLDEAGVAAMRDGGTVGVLLPGAFYFLRERQRPPVELLRRYQVPVAVASDFNPGTSPFCSLHLAMNMACVQFGLTPEEVWAGVTRHAARALGRQATHGQIRAGYRADFVVWDAEQPVEIVYEPGRNPLYQRVYRGQIS", "output": "Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway."}]}
+{"id": "function_test_1896", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSTQSRILVLNGPNLNLLGLREPAHYGSQNLEQIVNALTTQADALGVEIEHLQSNREYELIEAIHNAYQRIDFIIINPAAFTHTSVALRDALLGVDIPFIEVHLSNVHAREPFRHHSYLSDKAVGVICGLGADGYEFALNAAVKRLRSN", "output": "Catalyzes a trans-dehydration via an enolate intermediate."}]}
+{"id": "function_test_1897", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNRLPSSASALACSAHALNLIEKRTLNHEEMKALNREVIDYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGSLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRRPFMPLLPGFRHVPFGNIDAMSMAFSEGKKTGDEIAAVILEPIQGEGGVILPPQGYLTEVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDTLLDGFRQLAREYPNLVHDARGKGMLIAIEFVDNETGYRFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIELCEQVLKSARNALAAMQVSVEEV", "output": "Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4-aminobutanal. Also functions as a cadaverine transaminase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate."}]}
+{"id": "function_test_1898", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAENTMWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVETITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFTLVIDDGVNFVNQTHQTFDVIISDCTDPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQDEALDSHRKLSHYFSDVGFYQAAIPTYYGGIMTFAWATDNDALRHLSSEIIQARFHAAGLKCRYYNPAIHAAAFALPQYLHDALSAQ", "output": "Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine."}]}
+{"id": "function_test_1899", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNNAIFPNKFKAALAAQQVQIGCWSALASPITTEVLGLAGFDWLVLDGEHAPNDVTTLIPQLMALKGSASAPVVRVPTNEPVIIKRMLDIGFYNFLIPFVETQEEAARAVASTRYPPEGIRGVSVSHRANMFGTVPDYFAQSNKNITIIVQIESQLGVDNVDAIAATEGVDGIFVGPSDLAAALSHLGNASHPDVQQTIQHIFARAKAHGKPCGILAPVEADARRYLEWGATFVAVGSDLGAFRASTQKLADTFKK", "output": "Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde."}]}
+{"id": "function_test_1900", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLADRHLGVGFDQLLVVEPPYDPELDFHYRIFNADGSEVAQCGNGARCFARFVRLKGLTNKRDIRVSTANGRMVLTVTDDDLVRVNMGEPNFEPSAVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHCVIQVDDVDTAAVETLGPVLESHERFPERANIGFMQVVKREHIRLRVYERGAGETQACGSGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAVHVYDGFIHL", "output": "Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan."}]}
+{"id": "function_test_1901", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKIVKISPRGYCYGVVDAMVIARNAALDKSLPRPIYILGMIVHNKHVTDAFEEDGIITLDGPSRLEILDKIDSGTVIFTAHGVSPEVKQRAKEKGLTTIDATCPDVTKTHDLIEAKKAEGYHVIYIGKKNHPEPEGAVGIAPDIVHLIERADDLKTLEIPTDKILVTNQTTMSQWDVQHLMEDIQKKFPTAEFHKEICLATQVRQEAVAKQADVADLTIVVGDPKSNNSNRLAQVSQEIAGTKAYRVADVSEIQLEWLQGVENVAVTAGASTPTPITKEVIAFLDQYDPMNPATWERVRKVPLQKILPRVKVKKEQ", "output": "Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis."}]}
+{"id": "function_test_1902", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAGRLDEDLKDVTLLGNQNTKYLFEYSPEILEVFDNNHPNRDYFVKFNCPEFTSLCPKTGQPDFATIYISYIPEQRMVESKSLKLYLFSFRNHGDFHEDCMNVIMNDLIKLMDPRYIEVWGKFTPRGGISIDPYCNYGRPGTKYEQMADYRMMNHDLYPETIDNR", "output": "Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)."}]}
+{"id": "function_test_1903", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGYYSLTEVTAVQYAKEHGYFEKKANVVCHEIGDGNLNYVFKLDDGEKSIIIKQALPYAKVVGESWPLSIKRATIESKALQIFAKYVPEYVPVVYSHDEELAVTVIEDLSRLTITRKGLIDGEEYPLLSQHIGHFLANVLFYTSDFGLQSEEKRVLEGTFVNPDLCKITEDLVFTDPFGHYDTNDYEPELQLTIDELWSDKTLKLKVAQYKYKFLTRKEALIHGDLHTGSIFSSPSETKVIDPEFATYGPFGFDIGQLIANLLLNALSREEEQRGVLFFHIEKTWSYFVETFTKLWIGEGVEAYTKEKQWLPIILQNIFTDAVGFAGCELIRRTIGLAHVADLDEITNKETRIQAKKQALSLGKELIKYESKNADIQLFRTLFQQTVSGGIKA", "output": "Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate."}]}
+{"id": "function_test_1904", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLGALAKKIFGSSNDRRVKGFRPRVAAINALEPEISALSDEQLRARTQTFRDQLAAGTRLDDLLVPAFATVREAAKRVLGQRHFDVQMIGGMVLHESGISEMKTGEGKTLVATLPVYLNALEGKGVHVITVNDYLASRDAEWMGRVYRFLGLTVGTIVHGLDDGQRKEAYACDITYGTNNEFGFDYLRDNMKYELSQMTQRGHHFAIVDEVDSILIDEARTPLIISGPVDDRSELYVAVDTVMPRLTPEHYDLDEKQRQVSLTEAGNEFIEEELRAEGILKEGDLYDAHNVTIVHHVNQALRAHTLFTLDKDYIVKNDEVVIIDEFTGRMMQGRRYSEGLHQALEAKERVTIQPENQTLASITFQNYFRLYKKLAGMTGTASTEADEFAEIYKLDVVDIPTNKEVERVDEDDEVYRTVEEKYEAIIKEIDKAHARHQPILVGTGSIEKSELIGELLKKAGYTLLDYSDPNALTDVYKAARENRVTKRFAVLNARFHEQEAYIVAEAGVPGAITIATNMAGRGTDIKLGGNLEMRIEKELGQMPEGPERAAAIEALKAEIAENRAKVLASGEKADPEAGRKKDLPGGLYIIGTERHESRRIDNQLRGRSGRQGDPGRSKFYLSLKDDLMRIFGSDRMDGMLQRLGLEQGEAIIHPWINKAIEKAQQKVEARNFDMRKNVLKYDNVMNDQRKVVFEQRRDLMGQDSVRETVDEMRHGVIDDFVAVHIPENAYAEQWDAEGLKHRALDVLGLDLPIEEWVKEEGIADEEIRERLRKASDESYAARVERNGAEVMTYVEKQVVLQVLDHLWREHLVTLDHLRQVIGWRGFAQRDPLNEYKSEAFELFNGLVTALREQVTAQLSHVEIMQQQPEGFADGGFESAGFSEPQLPPMFPEHRDPVTGENEFAFAGSGSDGGAGGAYGFAARELSADAAVLERNPDDASTWGRVGRNEPCPCGSGKKYKHCHGRFATEA", "output": "Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane."}]}
+{"id": "function_test_1905", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLNIADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLHYCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVADVNLWFLENGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEYIPFPDKLKGRYQAFTQADLTNLRAAGYDKPFKTVAEGVTEYMAWLNRDA", "output": "Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose."}]}
+{"id": "function_test_1906", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSPVILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALHLDHHESLDDIRRKVHAGVRSAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEAKRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFVRRTIELGVTKVNVATELKIAFAGAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKINVCGSANRISA", "output": "Catalytic subunit of the tagatose-1,6-bisphosphate aldolase KbaYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP). Requires KbaZ subunit for full activity and stability."}]}
+{"id": "function_test_1907", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIPLQHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASALAFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSEMRG", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_1908", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG", "output": "Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor."}]}
+{"id": "function_test_1909", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKTPIYLDYAATTPVEFEVAKKMMNYLTIDGVFGNSASRSHKFGWKAEEVVDIARNQISELIGADSREIVFTSGATESNNLAIKGIASFHQNKGKHIVTSKTEHKSVLDTCRYLENKGFTVTYLTPKNNGIIDLNNLKKNIKKDTILVSIMHVNNEIGIIQDINSISQICRNHGVFFHVDATQSVGKIPIDLKKIPIDLMSFSAHKIYGPKGIGGLYVRRKPRVRLLSLIHGGGHERGMRSGTLPVHQIVGMGESFVLAKRKIHDDFIHLTKLKNILWNGIKNIEEVYLNSDLQQGAPHILNVSFNYVEGESLIMALKDLAISSGSACTSASLEPSYVLKSLGIRDELAHSSIRFSIGRFTTEKEIIHAIKLVHKSIHRLRELSPLWEMFKSGVDLNSIEWDHV", "output": "Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins."}]}
+{"id": "function_test_1910", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGMTIAEKILAAHAGQEEASPGDLINAKVDIALGNDITAPIAIKLFRQSGAAKVFDKDRVVLVPDHFTPTKDINSAMQVKMVRDFAREQELSHWYEGGDSGVEHALLPEKGIVGPGDLVIGADSHTCTYGGLGAFATGVGSTDLAAAMITGEVWLKVPESIKFVYKGKLRPHVEGKDLILHTIGDIGVDGALYMAMEFTGEVIDALPMAERLTMANMAIEAGGKAGIIAPDAKTKEYADGRVIRKPVFYASDPDAKYAKVIEYDVTDLEPQVAFPHLPENTRPISQVGEVPIHQVIIGSCTNGRIEDMRSAARILTGNKADKNVRLIIIPATPQIYRQAMEEGLFDTFLSAGAVISPPTCGPCLGGHMGILAAGERAVATTNRNFVGRMGHVESEVYLANPAVAAASAIAGKIAGPDDI", "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."}]}
+{"id": "function_test_1911", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLLDELVRTTDAVASTRSRLAKVDALAQLLKRLDPADIPAAVGLLTAKPRQGRVGVGWRGMSAAMGEPAADPGLTLADLDAALDRLQALAGAGSAAERAATLRGLTAAATEREQAFIGGVLLGELRTGALEGVLTDAVARAAERSVEAVRRAAMLSGDLGSTALLALTGTAAELDAVGLKVGRPVQPMLAGTGASVTAALETTGEASVEYKLDGARIQVHRSGGDVRIFTRTLAEVTHRLPEVVEVVRGFPVHDVILDGETLALGEDGAPRPFQETMSRFGADAARTTVLHPWFFDVLHIDGRDLLDEPLSERIKVLEAIAPAHRIPGEITADPEVAGRISRDALAAGHEGVMLKSVGSLYAAGRRGSNWIKVKPVLTYDLVVLACEWGSGRRTGMLSNLHLGALDPAGEYGEPGGYVMVGKTFKGLTDALLQWQTKRFQEIEVRRTAGTVWVEPVTVVEIAIDGVQQSPRYPGRIALRFARVKGYREDKTAAEADTIQTLRALLRP", "output": "DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair."}]}
+{"id": "function_test_1912", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQTLSAPDISSSKPAALTEATIVRRKTRPVPVGSITIGGGNPVVVQSMINEDTLDIEGSVAAIRRLHEIGCEIVRVTVPSMAHAKAMAEIRAKLHRTYKPVPLVADVHHNGLKIALEVANHVDNVRINPGLYVFEKPKADRTEYTQAEFDEIGAKIRETLEPLVLSLKTQNKSMRIGVNHGSLAERMLFTYGDTPEGMVESALEFIRICESLGYYHLEISLKASRVPVMLAANRLMVQRMDELGMDYPLHLGVTEAGDGEYGRIKSTAGIGTLLAEGIGDTIRVSLTEAPEKEIPVCYSILQALGLRKTMVEYVACPSCGRTLFNLEEVLHKVREATKHLTGLDIAVMGCIVNGPGEMADADYGYVGKQAGHISLYRGREEVKKVPEDQGVEELINLIKADGRWVDP", "output": "Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate."}]}
+{"id": "function_test_1913", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDRIHITGGAPLHGEIPISGAKNAALPLMIASLLTGETVELANVPRLADIASLLRILGNHGVDHMVVGKRPGQTAETGQTIRLTASNVIDTTAPYELVSTMRASFWVIAPLLARFGEARVSMPGGCAIGTRPVDLLLMAMERLGATIEIDGGYVVARTRNGLRGAEIVFPKVTVGGTHVALMAASLAQGTTVIDNAAREPEVVDLAECLSKMGARIEGAGTPRIVVEGVSRLGGARHEVLPDRIETGTYAMAVAMTGGDVILRDTRADLLHSALDVLATTGTEVTALPNGIRVRRNGAGVAAVDVTTDPFPGFPTDLQAQFMALMTKARGQSRIRETIFENRFMHVQELARLGARIRLEGDLAVVDGVERLRGAPVMATDLRASVSLVIAGLAAEGETIINRVYHLDRGFEALEAKLSRCGAQIRRERV", "output": "Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine."}]}
+{"id": "function_test_1914", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFVLGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQPDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGTDHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDKPGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE", "output": "Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source."}]}
+{"id": "function_test_1915", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNTLDFDKKPEDTRVVVAMSGGVDSSVVAGILKRQGYDVLGITLQLYDHGAAVHRAGSCCAGQDIDDARRVCETIGIPHYVLDYEKRFRETVINPFAESYVAGETPIPCVSCNQTVKFADLLATAKELGADALATGHYIRSRPNPSADHPGRRALYRPADADRDQSYFLFATTQEQIDYLRFPLGGMPKAETRALAEEMGLVVAKKADSQDICFVPQGKYSDVIAKLKPNAALAGEIVHLDGRVLGRHEGILHYTIGQRRGIGVATGDPLYVVFLDARSRRVIVGPKEALETHRVYLRDVNWLGDEPLLEAASGEGFACYAKVRSTRPPEPAVLRADKDGIYVDLTIGEAGVAPGQACALYSAPGDDARVYGGGFIERSEREPMAEASLKALLASPVAA", "output": "Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34."}]}
+{"id": "function_test_1916", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDARNRLIVGLDVATVTEAEKLVSTLAEDVTFYKIGYQLAFAGGLEFARDLAQSGKKVFLDMKLLDIDNTVASAVENIVRMGMTMLTLHAYPKAMQAAVEAAQGSGLCLLGVTVLTSMDDQDLNDAGYQGDARSLVLKRAAQAKEKGMGGIVCSAQEAQAVRAILGSDMAIVTPGIRPAGSDAGDQKRVMTPADAIHAGSSHLVVGRPIVKADDPRAATQVILAEMQAAFT", "output": "Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP)."}]}
+{"id": "function_test_1917", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDKESITNAEENSYDKPNNNIRPQGFDDFLGQNNIKSKLKVFINSAKKREVSLDHILFYGPPGLGKTTLAQIIANEMGSNIKATSAPIIERPGDLASILTTLGEKDILFIDEIHRLRTVVEEVLYSAMEDFFVDIKVGEGTSAKSFRVKLPHFTLIGATTRSGLLSTPLYDRFGIVERLEFYTNEDLANIVKRSSEFLNINITDEAAISIASRSRGTPRIVNRLLRRVFDFATVHDVLKIDEKFACDSLEKLGIDKNGFEALDKLYLNTIIKHYNGGPVGVDTLSVSLSEQIETIEDVIEPYLIQCGFIKRTPKGRVATNKAYGYLNLSSKYDDNYSNEERGLFDF", "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA."}]}
+{"id": "function_test_1918", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGRLFGTDGVRGLANSDLTADLALRLAVAAASVLTAGTSDARPTAVIGRDPRASGEMLQAAVTAGLSSAGVDVLDVGILPTPAVAYLTAKLEASLGVMISASHNPMPDNGIKIFAAGGHKLDDAVEVAIEDALDGTAPPVLPTGAGIGRVRAVDDAAQLYLAHLASAASEPLAGLTVVVDCANGAASALAPVAYAAAGARVIAISADPDGLNINDGCGSTHLENLQKAVVDHGADLGLAHDGDADRCLAVDETGAVVDGDAIMAVLAIAMNEAGELVENTLVATVMSNLGLHIAMREAGINIVTAAVGDRYVLEELRAGGYSLGGEQSGHVVLPAFGTTGDGILTGLRLLGRMARTRKSASVLAATMTTLPQVLINVKVGDKAAVAASPSVLAAVADAERVLGDGGRVLLRPSGTEQLVRVMVEATELPLAQKLADELAEIVGSV", "output": "Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate."}]}
+{"id": "function_test_1919", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAEKFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQVTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQDGRDLLEKAGYPVLSLARLDRFENGQVVFKEADL", "output": "Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis."}]}
+{"id": "function_test_1920", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQATVKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQVYSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYDYVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSIGGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTRIARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIRLTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF", "output": "Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)."}]}
+{"id": "function_test_1921", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLVLGIESTAHTFGVGIAKDQPPYILANERDTFVPKEGGMKPGDLLKHHAEVSGTILRRALEKANISINDINYIAVALGPGIGPALRVGATLARALSLKYNKKLVPVNHGIGHIEIGYLTTEAKDPLILYLSGGNTIITTFYKGRFRIFGETLDIALGNMMDVFVREVNLAPPYIINGKHAIDICSEKGSKLLKLPYVVKGQDMSFSGLLTAALRLVGKEKLEDICYSIREIAFDMLLEATERALALTSKKELMIVGGVAASVSLRKKLEELGKEWDVQIKIVPPEFAGDNGAMIAYAGMLAASKGVFIDVDKSYIRPRWRVDEVDIPWRN", "output": "Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37."}]}
+{"id": "function_test_1922", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSNNMIRLATRQSPLALWQAHYVKTGLEFFHPDLKVILLPMVTQGDNILGTALSKTGGKGLFVKELERAVLDNRADIAVHSIKDMPLYFPEGLGLVAVCEREDPRDAFLSLRYHDVAQLPEGSVVGTSSLRRQCQLYKNYPGIVVRDLRGNVGARLKKLDQGDYDAIVLAVAGLKRLGLENRMTQILRPETSLPAAGQGAIGIECRLDDTVTLQRVATLNHRPSQLKISCERALLKRLEGGCQTPIGSYAEIENDELWLRAFVGAPDGQLIIDGERRGNFDSAEKIGFELANELLSRGAEAILAQLNRQ", "output": "Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps."}]}
+{"id": "function_test_1923", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNTLPEQYANTALPTLPGQPQNPCVWPRDELTVGGIKAHIDTFQRWLGDAFDNGISAEQLIEARTEFIDQLLQRLWIEAGFSQIADLALVAVGGYGRGELHPLSDVDLLILSRKKLPDDQAQKVGELLTLLWDVKLEVGHSVRTLEECMLEGLSDLTVATNLIESRLLIGDVALFLELQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPDIKSSPGGLRDIHTLQWVARRHFGATSLDEMVGFGFLTSAERAELNECLHILWRIRFALHLVVSRYDNRLLFDRQLSVAQRLNYSGEGNEPVERMMKDYFRVTRRVSELNQMLLQLFDEAILALPADEKPRPIDDEFQLRGTLIDLRDETLFMRQPEAILRMFYTMVHNSAITGIYSTTLRQLRHARRHLQQPLCNIPEARKLFLSILRHPGAVRRGLLPMHRHSVLGAYMPQWSHIVGQMQFDLFHAYTVDEHTIRVMLKLESFASEETRQRHPLCVDVWPRLPSTELIFIAALFHDIAKGRGGDHSILGAQDVVHFAELHGLNSRETQLVAWLVRQHLLMSVTAQRRDIQDPEVIKQFAEEVQTENRLRYLVCLTVADICATNETLWNSWKQSLLRELYFATEKQLRRGMQNTPDMRERVRHHQLQALALLRMDNIDEEALHQIWSRCRANYFVRHSPNQLAWHARHLLQHDLSKPLVLLSPQATRGGTEIFIWSPDRPYLFAAVCAELDRRNLSVHDAQIFTTRDGMAMDTFIVLEPDGNPLSADRHEVIRFGLEQVLTQSSWQPPQPRRQPAKLRHFTVETEVTFLPTHTDRKSFLELIALDQPGLLARVGKIFADLGISLHGARITTIGERVEDLFIIATADRRALNNELQQEVHQRLTEALNPNDKG", "output": "Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism."}]}
+{"id": "function_test_1924", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDTLNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGLNAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQDE", "output": "Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate."}]}
+{"id": "function_test_1925", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits."}]}
+{"id": "function_test_1926", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT", "output": "Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP)."}]}
+{"id": "function_test_1927", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIIKPKVRGFICTTTHPVGCEANVRRQIAYTQAKGPIENGPKKVLVIGASTGYGLASRIAAAFGAGAATIGVFFEKPGTETKTGTAGWYNAAAFDKAAKEAGLYAKSVNGDAFSNECRQQVIELIKQDLGQVDLVVYSLASPVRKLPDTGEVVRSALKPIGEVYTTTAIDTNKDQIISASVEPATEEEIQNTITVMGGQDWELWMSALRDAGVLADGAKSVAYSYIGTDLTWPIYWHGTLGRAKEDLDRAAAGIRGDLAAHGGTAHVAVLKSVVTQASSAIPVMPLYISMSFKIMKEKGIHEGCMEQVDRMMRTRLYGSDMALDDHARIRMDDWELRDDVQQTCRDLWPSITSENLSQLTDYSGYKQEFLRLFGFGLDGVDYDADVNPDVQFDVVTL", "output": "Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP)."}]}
+{"id": "function_test_1928", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDVFKPEKLFGIIGHPLGHTMSPLLHNWGFAEHKIPAVYMAWPTEPEKVESFMQTFRNLPISGASVTIPHKLSVMDYIDQLTERAESVGAVNTLYWDGDKIVGDNTDAAGVSEPLRPYSDQIKKALLIGAGGAARAAITGLQSLGIKEIFITNRTKSKADDLAAEFKISALDWDARGDQHLDLIVNSTSLGMSGKFEEINPMIMENQDKNTIIFDLVYNPLETVLIRKAKSKGCTVIHGIEMFVHQGLEQFRLWTGIKLDEKKARELLLEKL", "output": "Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)."}]}
+{"id": "function_test_1929", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MFCNQCEQTAKGQGCTVKGVCGKTDEVSAIQDLLVQVLVELGTVATAARKEGIAVSNEVNRLTAEGVFSTLTNVNFDDERFVPVIKNVAAARDELAAKVSADCGKLTKVAGTAAELSKQGEAFPVTSFDENEDLRSLKQILVYGLKGVAAYTDHAAILGQEDDELYAQIHEALSVVPQQLGMEELVGWAMKCGEMNLKAMELLDAGNTGAYGHPVPTEVPLGAKAGKAILVSGHDLKDLRQLLEQTEGTGINIYTHGEMLPCHGYPELKKFDHFYGHYGTAWQNQAKEFAQFPGAILMTTNCIQKPVESYKGNIYTTGLVGWPGVTHVTNGDFAEVIAKAQELPGFEADTDNGKVLCGFARNTVLGVADKVIEGVKAGAIKHFFLVGGCDGAKPGRNYYTDFVEQAPQDTVILTLACGKFRFFDKQLGDIGGIPRLLDIGQCNDAYSAIQIAVALANAFECGVNDLPLSMVLSWYEQKAVSILLTLLHLGIKDIRLGPSLPAFVTPNVLNFLVENFNIMPISTPEEDLKAILG", "output": "Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O."}]}
+{"id": "function_test_1930", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTENQQLTALLAACHWIGEKGWCPATGGNMSVRLDDAQCLITESGKDKGSLQAEDFLLVEIATNHVPSGRTPSAETGLHTLLYRREPTIGAVLHTHSVNATVLSRVEKGAELVLHGYEMQKSLAGQTTHLDRVAIPIFDNDQDIPALAQRVTEYASHTPLRYGFLVRGHGLYCWGATVKEARRHLEGLEFLFQCELQRRLLEAKA", "output": "Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P)."}]}
+{"id": "function_test_1931", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MANKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGNGRIIACDILPMDPIVGVDFLQGDFRDELVLKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPKSMYLVELALGMCRDVLAPGGSFLVKVFQGEGFDEYLREIRSLFTKVKIRKPDASRARSREVYIVATGRKL", "output": "Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit."}]}
+{"id": "function_test_1932", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDSWTSPDVPALPFTAEGPRVHDTARGAITPLTPRPGQEAGLYVCGITPYDATHLGHAATYLTFDLVNRALRAAGHPVRFVQNVTDVDEPLLERAERDGVHWEELASREIQLFRDDMAALRIIAPDAYVGAVEGIPSDVAAIRAMLESGRAYRVPAEDAAADAGESPADVYLDLAQVPTFGEVSHWTPTQMMEVFADRGGDPDRAGKRDRLDPLLWRAHREGEPHWEGGSLGAGRPGWHIECTTIARDHLGTPFLVQGGGDDLVFPHHEMSAAQTRALTDDAFAEHYVHQAMVGLDGEKMSKSKGNLVLVSRLRAAGEDPAAIRLALLSQHYRTAWEWTDAHLEAARQRLDRWRHAAQTATASPSTADAEDAPAGDAVARQLAERIADDLDAPGALAVVDRWADAVLGEQTGAAAAAARAEARGVRTAVDALLGIDLG", "output": "Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins."}]}
+{"id": "function_test_1933", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAAQVEDDVANLKLDDSTTKPTNGTSQPDSKLSAEAEDSDDDAEGDGNGTGEAGADGAAKKKKKRKPRKKKKAGTSATAGAKSQTSPPRVLISDLFPNDSYPEGEICEYRDENSYRTTNEEKRHLDRMNNDFLTDYRKGAEIHRQVRQWAANWIKPGMTLTEIAEGIEDSVRALTGHQGLEEGDAQKAGMGFPTGLSINHCAAHYTPNAGNKVVVNYEDVMKVDFGVHINGRIVDSAFTKTFDPVYDPLVEACKAATNAGIKEAGIDVRMSDIGAAIQEVMESYEVEIGGKMLPVKCIRNLNGHSIGHYTIHGGKTVPIVKGSDQTKMEEGETFAIETFGSTGKGYVRDDMETSHYALRPDAPKVALRISSAKSLLASITKNFGTLPFCRRYLDRLGHDKYLLGLNNLVSSGIVEAYPPLCDIKGSWTAQSEHTFVLRPTCKEVLSRGDDY", "output": "Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val)."}]}
+{"id": "function_test_1934", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAVEEKNSPTGAAMTNTGILVPSSQQSLPEWWTKTQKFFSRENTITPTFGYFRLLFGTQPGKTDIALIVIGTIAGIGAGIPFPLLGILFGELVDDLNSSTCSTTQAPPGGYQAAITTKVLQVIYVSILNFVCMYIHTGCWSMVGERLVRRLRTKYFHSLLRQEIAFTDTLPSGDVTSRLVSDIEVIQAGTSEKVGLFIGTISYFVAAYIVAFLKVATIAAMLMSVVPIYFLMAFGGGHYIKKYSGRISTHINAATSIVSSSLSHMSIVHAFNANARLEALFAQHLVSARMDALKKAITHSIQFGMLYFVAYASNALAFWQGSRMIADLAEGKPSKVSVGAVYTVIFVLLDASFVLSQMAPFMHIFASAASAGDRLMTTIKRQSAIDGTSSEGDSTISLASEEIELQDVTFNYPARPEVPVLQGVSFKIPPNKHTAIVGTSGSGKSTVVALLERLYDPITGCVRVGNRDLKEINVRHLRGSIGLVQQEPNLLDRSILENIAHGLVSSSQEKHKHLLPTLLGPSLSELTEKIRQGASEDEAVTEQGDVVREIVNLTRHAATLSNAIDFINALPDGLATRVGSSGAELSGGQKQRIALARALIRDPPVLLLDEATAALDSTSERLIQAALNKVSENVTTVSIAHRLATAKDADNIIVMQKGRVMEQGTHMDLVARDGVYAGMVRLQNIGKFSSSSSIMTESTQVDANIDRSLTTDTLLNKEEKLSLEQGVLDEKEKPAQLYMPEEADSLPTEPENEKEKPKQTLWATMKGSFPLIRPNILLISLGLITSIMIGVSYTGEAVIFGHTVGSLSVCRGGPSIRSSGMLFGLLFFILAIVKFAAVIVNGAAFGWAAEKTLYRTRVLSLRSLLRQPLEWHNADGRTPGLLVALVTSDASALSSLTGTTIGVLFSTVANLFAGVILSQCHRMEDSRSPSGYLTRIKHQKAYAKATAITVESVDNIKSIAAFSLEQEAYSVFNRSLKAPYKSNMKSVLHGNFWLSLAYSISTLVYALAYWWGSQQILAGMYTQVQFFIVLPALLFSTQSCGQMFALVPDISKARIAASNIVDLLSIKHEGDEEYDKTGSKASAKHTDPRFNMLEDKPRDVEAQLITTTPSSFPTKGMGVQFRNVHFRYPSRPNQPALDDLSINISPGQFCALVGPSGSGKSTTFALLEKFYNPASGSIIIDGVDITKQSGAAFRDTIALVPQENVMFEGTVAFNIGLGARPDVEATQEEIEEACRLANIHDTIAALPDGYNTVCSQDGKQFSGGQRQRLSIARALVRKPRLLLLDESTSALDVESEKHVQDALAKVARKTTIVAIAHRLNTIHRADRIFMIERGRCVDQGTHAELVERCESYRANVIHQSLDA", "output": "Pleiotropic ABC efflux transporter that may be involved in the modulation susceptibility to a wide range of unrelated cytotoxic compounds."}]}
+{"id": "function_test_1935", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPPLILHNVPDDELYVGDDGIQRPFAMVFPQQDGSLRSRKANLETGAFGKSTRRTRSKAATPAKREDPTIAAADKIFSNWLASQNQSAPQTSVPAPAQRKPNLIPSSSSQNLAQGHDESSAPSQTRFFRKQEPTEVILRGYRNAQHQYAAINHYEQIAGRICEDYPREPPVESRRYKSELRDPAFTHRRALTPEERAKVNRAMSGEHWVKVTFESAEAADKAVYSSPQLIQGHLVYAEYYKGVPPAQDEAIPDPSVAAFGAALSRTQTLRQRNRGSFSLSGTQEAGGPDASPTSSLTADTGTLASGVEISTSTSNTLNGGAAAGGAEKSQDDEFCRVIPTVRKAKLLPMEEALLPAPTFTQRIANHIPFLRWFNGAMIGSEVPRTETGEFDWVRASLFWKLMWWLDFLLGLFGGDIRDAEKDDKED", "output": "Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope (GSP1 and GSP2 GTPases associated predominantly with GTP in the nucleus, with GDP in the cytoplasm)."}]}
+{"id": "function_test_1936", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSCISRSRALFQIRSLASSSHLPLPKLRPSPAIYKSANKTAFNASPSTSQSATTTRGFRSTAAKMTVHNLTNAQDFKDALKSHKFVLVDFFATWCGPCRAIAPKIAEWSDAFPNIHYVKVDVDEVPDVAQEYNVRAMPTFLLFKDGEKVDEVVGANPPKLQALISANHPSS", "output": "Thioredoxin involved in responses to oxidative and cell wall stresses . Plays an important role in appressorium formation on hyphal tips . TRX2 may affect invasive growth via the MST11-MST7-PMK1 pathway since it is required for the proper folding or dimerization of MAPKK MST7 ."}]}
+{"id": "function_test_1937", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "AIAAVITFLILFTIFGNALVILAVLTSRSLRAPQNLFLVSLAAADILVATLIIPFSLANELLGYWYFWRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVSRALEYNSKRTPRRIKCIILTVWLIAAAISLPPLIYKGDQGPQPRGRPQCMLNQEAWYILSSSIGSFFAPCLIMILVYLRIYLIAKRSNRRGPRAKGAPGEGESKQPHPLTAGPLALANPPTLATSLAVDGEANGHSKLTGEKERETSEDPGTPTLQRSWPVLPSSGQSQKKGVCGASPEEEAEGEEEGSRPLSVPASPASACGPHLQQPQGSQVLATLRGQVLLGRGVGAAGGQWWRRRAQLTREKRFTFVLTVVIGVFVLCWFPFFFSYSLGAICPQHCKVPHGLF", "output": "Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins."}]}
+{"id": "function_test_1938", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIDNLIKKEFLAHKEALEKSLEGLQEALKQSVHLLIETLENQGKILICGNGGSASDAQHFAAELTGRYKLERKGLSAISLNTDISALTAIANDYGYEEVFARQVEALGVKNDVLIGISTSGNSKNVLKAYEKAKDLEMKTLSLAGRDGGKMKPLSDMALIVPSDDTPRIQEMHILMIHILCDCIERHFAHKN", "output": "Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate."}]}
+{"id": "function_test_1939", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQNHDLESIKQAALIEYEVREQGSSIVLDSNISKEPLEFIIGTNQIIAGLEKAVLKAQIGEWEEVVIAPEEAYGVYESSYLQEVPRDQFEGIELEKGMSVFGQTEDNQTIQAIIKDFSATHVMVDYNHPLAGKTLAFRFKVLGFREVSEEEILASHHGGGTGCCGGHGGHGGKKGGGCGCSCSHG", "output": "Folding helper with both chaperone and peptidyl-prolyl cis-trans isomerase (PPIase) activities. Chaperone activity prevents aggregation of unfolded or partially folded proteins and promotes their correct folding. PPIases catalyze the cis-trans isomerization of Xaa-Pro bonds of peptides, which accelerates slow steps of protein folding and thus shortens the lifetime of intermediates. Both strategies lower the concentration of intermediates and increase the productivity and yield of the folding reaction (By similarity).; "}]}
+{"id": "function_test_1940", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAQRRKITAIVGLEQYNAGLWRKIKSMLDKDAELVQLSDVDLEKQNPEAATAIREADCVFMSMINFKEQIDWFKEQLDQAINEKTIFIFESMPEAMALTKVGSYQVTEGKSGMPDMVKKIAKMLVKGRDEDALYGYMKLMKIMRTILPLVPNKAKDFKNWLMVYSYWLQPTPENIVNMFRLILREYFDSNVKVEPIVDVPNMGLYHPDAKEYFKDVKSFKSWSKKRGVNFDKSQKMALLFFRKHLLQEKTYIDNTIRTLEKHGVNVFPAFVMGVEGHVLVRDWLMKEKIDLLVNMMGFGLVGGPAGSTKPGTAADARHEILTGLDVPYMVAQPLLVQDFESWHELGVSPMQVTFTYSIPEMDGATAPVILGALQDGKVETVQERLDRLAILSKKWMRLRATSNRDKRVALVVYDYPPGLGKKATAALLDVPTTLLRILERLKKEGYNVGTLPESPTKLFEMLDRATDYQIMQNKPEAIKVSREKYNELATYHERERIEERWQAFPGEIAPVGSEEVFLGGLRLGNIYIGVQPRLGVQGDPMRLIFDKANTPHHQYISFYRWISREFDAHALVHVGMHGSVEWMPGLQTGLTGECWPDALLGEVPHFYIYPVNNPSESTIAKRRGLATMVSHVVPPLARAGLYKELPALKDLLADYRERNQAQGEDVEQVQEAIMTKAELLNLTDDCPRRPDEPFSDFVSRLYIYIVELENRLISNSLHVFGEAGPLESQIITITETIKNRGENGRSLPYIFIDTSGRNGHYGSYEEISSLSRKGDEAAIQLREWAENACREFVKQTMFDRKNPMQVFESVTGGGRMPEEDKPFIQRIIQEGAMMIQALSDNSSEMNSLVKVLDGGYIPSGPGGDLVRDGMNVLPSGRNIHSIDPWRIPSETAFKRGTLIADGLISKHVAENDGQYPETIAEVIWGLDTIKTKGEAVAVVIRLMGAEPAYDAFGKISHYNLTPLDKLGRPRVDVLMQLSPIFRDAFGILMDQLDRLVKDAAKADEPHEMNFIKKHVDEALAEGMDFEAATSRQFTQAPGAYGTYVDDMIEDSAWENEGDLDDLFIRRNSSAYGGGRKGEKQSEILQKLLGSVDRVVHQVDSTEFGISDIDHYFSSSGSLQLAARRRNTKTSDIKLNYVESFTSDIKLDEADKSLRVEYRSKLLNPKWFEGMLKHGHSGAGEISNRVTYMLGWDAVTKSVDDWVYKKTAETYALDPEMRERLATLNPQAIKNIVGRMLEAHGRGMWKADQSMIEELQEIYADLEDRLEGMADDD", "output": "Involved in bacteriochlorophyll pigment biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoroporphyrin IX."}]}
+{"id": "function_test_1941", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGKRVVYPGTFDPPHYGHLDIVKRSARIFDEVVVAVAKKPRKFLLFDAEERVKMFEKMVEDIPNVEVKMFDCLLVDFMKREGINVIVRGVRLFTDFEYELQIALTNYKLAGVETVFMMPSQEYIHISSTIVRDVASYCGDLDNMVHPYVKQKLREKFNCGS", "output": "Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate."}]}
+{"id": "function_test_1942", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEQTLRVSVFGATGYTGIELLRSLLTHPHFEVKNLISQSYKGKKVREVLPFFSNTYISEIEFLEEPVEDYELAFLCLPHEVSYEIVPKLLSQGKKVVDLSGAYRIKSPKAYEEFYGFKHEREDILQRAVYGLPEVFREEIKNSDLVANPGCYPTATLLAIYPFLKERVGIESVIVHALSGVSGAGRKPKQQFHFPEMTENFFNYAVEKHRHTPEMEDVIRRVYGREVKVRFTPTVVPTSRGMISTVYLKSEKLNVKELFKEVYEDEIFVKVVDEPPQTKWVLGTNYCFIYPHYDERTGYYVIISAIDNLGKGASLQAVQNANLMFGLAEDDGLLQLPVFP", "output": "Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde."}]}
+{"id": "function_test_1943", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAARLCCQLDPARDVLCLRPVGAESRGRPFSGPFGTLSSPSPSAVSTDHGAHLSLRGLPVCAFSSAGPCALRFTSARRMETTVNAHQFLPKVLYKRTLGLSVMSTTDLEAYFKDCLFKDWEELGEETRLMIFVLGGCRHKLVCAPAPCNFFTSA", "output": "Multifunctional protein that plays a role in silencing host antiviral defenses and promoting viral transcription. Does not seem to be essential for HBV infection. May be directly involved in development of cirrhosis and liver cancer (hepatocellular carcinoma). Most of cytosolic activities involve modulation of cytosolic calcium. The effect on apoptosis is controversial depending on the cell types in which the studies have been conducted. May induce apoptosis by localizing in mitochondria and causing loss of mitochondrial membrane potential. May also modulate apoptosis by binding host CFLAR, a key regulator of the death-inducing signaling complex (DISC). Promotes viral transcription by using the host E3 ubiquitin ligase DDB1 to target the SMC5-SMC6 complex to proteasomal degradation. This host complex would otherwise bind to viral episomal DNA, and prevents its transcription. Moderately stimulates transcription of many different viral and cellular transcription elements. Promoters and enhancers stimulated by HBx contain DNA binding sites for NF-kappa-B, AP-1, AP-2, c-EBP, ATF/CREB, or the calcium-activated factor NF-AT."}]}
+{"id": "function_test_1944", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MASSNLLSLALFLVLLTHANSASQTSFSFQRFNETNLILQRDATVSSKGQLRLTNVNDNGEPTLSSLGRAFYSAPIQIWDNTTGAVAASPTSFTFNIDVPNNSGPADGLAFVLLPVGSQPKDKGGLLGLFNNYKYDSNAHTVAVEFDTLYNVHWDPKPRHIGIDVNSIKSIKTTTWDFVKGENAEVLITYDSSTKLLVASLVYPSLKTSFIVSDTVDLKSVLPEWVIVGFTATTGITKGNVETNDILSWSFASKLSDGTTSEALNLANFALNQIL", "output": "This insecticidal carbohydrate-binding lectin is toxic for the cowpea weevil."}]}
+{"id": "function_test_1945", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAANGAKGRKVMRVLVVDNYDSFTYNLVQYLGELGAEPIVWRNDRFRLEEVEALDPDRILISPGPCTPFEAGLSVPLVQRYAPRYPILGVCLGHQAIGAAFGGKVVPAPVLMHGKVSPIHHDGTGVFRGLDSPFPATRYHSLAVVEVPEALVVNAWAEEAGGRTVMGFRHRDYPTHGVQFHPESYLTEAGKLILKNFLEDPWTR", "output": "Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity)."}]}
+{"id": "function_test_1946", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "VLSAADKANVKGVFSKIGGHADDYGAETLERMFIAYPQTKTYFPHFDLHHGSAQIKAHGKKVAAALVEAVNHIDDITGALSKLSDLHAQKLRVDPVNFKFLGHCFLVVVAIHHPAALTPEVHASLDKFMCAVGAVLTAKYR", "output": "Involved in oxygen transport from the lung to the various peripheral tissues."}]}
+{"id": "function_test_1947", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MANKQVEISMAEWDVMNIIWGKKSVSANEIVVEIQKYKEVSDKTIRTLITRLYKKEIIKRYKSENIYFYSSNIKEDDIKMKTAKTFLNKLYGGDMKSLVLNFAKNEELNNKEIEELRDILNDISKK", "output": "Transcriptional repressor that constitutively blocks expression of beta-lactamase. Binds DNA as a dimer (By similarity)."}]}
+{"id": "function_test_1948", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNKTQLIDVIADKAELSKTQAKAALESTLAAITESLKEGDAVQLVGFGTFKVNHRAERTGRNPQTGKEIKIAAANVPAFVSGKALKDAVK", "output": "Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions."}]}
+{"id": "function_test_1949", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKLKTILCAALLLVAGQAAAQEKSITIATEGGYAPWNFSGPGGKLDGFEIDLANALCEKMKAKCQIVAQNWDGIMPSLTGKKYDAIMAAMSVTPKRQEVIGFSIPYAAGINGFAVMGDSKLAEMPGLGETYSLDSQADAAKKAIADISSFLNGTTVGVQGSTTASTFLDKYFKGSVDIKEYKSVEEHNLDLTSGRLDAVLANATVLAAAIEKPEMKGAKLVGPLFSGGEFGVVAVGLRKEDTALKADFDAAIKAASEDGTIKTLSLKWFKVDVTPQ", "output": "Component of the octopine active transport system probably consisting of four subunits: Q, M, P and T."}]}
+{"id": "function_test_1950", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDPQNALYYQPRVPTAAPTSGGVPWSRVGEVAILSFVALICFYLLYLWVLRDLILVLKARQGRSTEELIFGGQAVDRSNPIPNIPAPPSQGNPGPFVPGTG", "output": "Involved in the viral transport within, and between cells."}]}
+{"id": "function_test_1951", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSTVNQSSTRSELAGNWERLRKSCDTCQEAKVKCSQHKPSCHRCLRHRQPCVYSPQRRSGRPPKRPSPSSRLGPESNNSGDDIHNENTIQRTNLNANDSAMTDAGAVDPRVLTGDFAASTGIDPVDDIFQTSFESFLAASLSPKGGLLPGSHSNPTTPNGFSMNSPSITDPFGAFPFLITDHNLPIAALSSHVPPIDQLPVLSTGASNTSSECGDCGAKCYSSLLQHLLFLRQTLPESTRPSIDVIMQAEGHVRALLDRVLGCNACLGNRSSILLISAITERIVQMLDWIIEEKTLLDTENMRYNRRTFSSWGRPPRLPPHGLNGMRRNVCHVSLRVGNTELDEDAKQYFLKNFILLRLKKLAVKVQEVRRTATTRPGDCIYRAAELVLADSIQRLDYLRGQCQLWE", "output": "Transcriptional regulator involved in the positive regulation of the expression of the gene cluster that mediates the biosynthesis of asperlin, a polyketide showing anti-inflammatory, antitumor and antibiotic activities."}]}
+{"id": "function_test_1952", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRKKLTALVLSALPLAAVADVSLYGEIKAGVEGRNIQAQLTEQPQVTNGVQGNQVKVTKAKSRIRTKISDFGSFIGFKGSEDLGEGLKAVWQLEQDVSVAGGGASQWGNRESFIGLAGEFGTLRAGRVANQFDDASQAINPWDSNNDVASQLGIFKRHDDMPVSVRYDSPEFSGFSGSVQFVPAQNSKSAYKPAYYTKDTNNNLTLVPAVVGKPGSDVYYAGLNYKNGGFAGNYAFKYARHANVGRNAFELFLIGSATSDEAKGTDPLKNHQVHRLTGGYEEGGLNLALAAQLDLSENGDKAKTKNSTTEIAATASYRFGNAVPRISYAHGFDLIERGKKGENTSYDQIIAGVDYDFSKRTSAIVSGAWLKRNTGIGNYTQINAASVGLRHKF", "output": "Serves as a slightly cation selective porin. Major antigen on the gonococcal cell surface and it may have pathogenic properties in addition to its porin activity."}]}
+{"id": "function_test_1953", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSDEQHQNLAIIGHVDHGKSTLVGRLLYETGSVPEHVIEQHKEEAEEKGKGGFEFAYVMDNLAEERERGVTIDIAHQEFSTDTYDFTIVDCPGHRDFVKNMITGASQADNAVLVVAADDGVQPQTQEHVFLARTLGIGELIVAVNKMDLVDYGESEYKQVVEEVKDLLTQVRFDSENAKFIPVSAFEGDNIAEESEHTGWYDGEILLEALNELPAPEPPTDAPLRLPIQDVYTISGIGTVPVGRVETGILNTGDNVSFQPSDVSGEVKTVEMHHEEVPKAEPGDNVGFNVRGVGKDDIRRGDVCGPADDPPSVAETFQAQIVVMQHPSVITEGYTPVFHAHTAQVACTVESIDKKIDPSSGEVAEENPDFIQNGDAAVVTVRPQKPLSIEPSSEIPELGSFAIRDMGQTIAAGKVLGVNER", "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."}]}
+{"id": "function_test_1954", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSLWRPSEATVYLPPVPVSKVVSTDEYVTRTNIYYHAGSARLLTVGHPYYSIPKSDNPKKIVVPKVSGLQYRVFRVRLPDPNKFGFPDTSFYNPETQRLVWACVGLEVGRGQPLGVGISGHPLLNKFDDTENSNRYAGGPGTDNRECISMDYKQTQLCLLGCKPPIGEHWGKGSPCSNNAITPGDCPPLELKNSVIQDGDMVDTGFGAMDFTALQDTKSNVPLDICNSICKYPDYLKMVAEPYGDTLFFYLRREQMFVRHFFNRSGTVGESVPTDLYIKGSGSTATLANSTYFPTPSGSMVTSDAQIFNKPYWMQRAQGHNNGICWGNQLFVTVVDTTRSTNMSVCAAIANSDTTFKSSNFKEYLRHGEEFDLQFIFQLCKITLSADIMTYIHSMNPAILEDWNFGLTTPPSGSLEDTYRFVTSQAITCQKTAPQKPKEDPFKDYVFWEVNLKEKFSADLDQFPLGRKFLLQAGYRARPKFKAGKRSAPSASTTTPAKRKKTKK", "output": "Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2."}]}
+{"id": "function_test_1955", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNNSSELIAVINGFRNSGRFCDISIVINDERINAHKLILSGASEYFSILFSNNFIDSNEYEVNLSHLDYQSVNDLIDYIYGIPLSLTNDNVKYILSTADFLQIGSAITECENYILKNLCSKNCIDFYIYADKYNNKKIESASFNTILQNILRLINDENFKYLTEESMIKILSDDMLNIKNEDFAPLILIKWLESTQQSCTVELLRCLRISLLSPQVIKSLYSHQLVSSIYECITFLNNIAFLDESFPRYHSIELISIGISNSHDKISINCYNHKKNTWEMISSRRYRCSFAVAVLDNIIYMMGGYDQSPYRSSKVIAYNTCTNSWIYDIPELKYPRSNCGGLADDEYIYCIGGIRDQDSSLTSSIDKWKPSKPYWQKYAKMREPKCDMGVAMLNGLIYVMGGIVKGDTCTDALESLSEDGWMKHQRLPIKMSNMSTIVHDGKIYISGGYNNSSVVNVISNLVLSYNPIYDEWTKLSSLNIPRINPALWSAHNKLYVGGGISDDVRTNTSETYDKEKDCWTLDNGHVLPRNYIMYKCEPIKHKYPLEKTQYTNDFLKYLESFIGS", "output": "Probable substrate-specific adapter of CUL3-containing E3 ubiquitin-protein ligases which mediate the ubiquitination and subsequent proteasomal degradation of host target proteins."}]}
+{"id": "function_test_1956", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRNIIVEPLNQTPIEDQKVEIVERKGIGHPDSISDGIAESVSRALCNAYLDRFGAIMHHNTDEVQITAGESAPQFGGGEVIKPIEILLTGRGIAEVDGEKIGLDRIAISAAKEYLRDNIINLDVETCTVVECKIGHGSGDLRDVFARKGRAPLSNDTSFGVGFAPFSETERIVMEAENLLNSPEFKKKYPAVGEDIKVMGLRENDNITLTVACAMVDRYVSDLEEYLEIKNVVKDEVFKLASGITERNLEVFVNTADRCEDDEPSVYITVTGTSAEMGDDGSVGRGNRANGLITPNRPMSMEATSGKNPINHVGKIYNLLSNQMAADIVESIEGVKQVHIMILSQIGKPIDHPKAATAQVILEDGYTMDDITGKVSGVMDAWLEDIPSITEMLVKGQLRTF", "output": "Catalyzes the formation of S-adenosylmethionine from methionine and ATP."}]}
+{"id": "function_test_1957", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNKLILIIDNYDSFTHNLYQMAGEIMMEMDSADIMVVRNDEVDIDYVRGLDPERIIISPGPGNPIKREDFGICSEVIGEFTDRPILGVCLGHQGIFHYFGGVVGYGEPVHGKISEVFHDGSELFRGVPNPFRATRYHSLRCECSGVPEDILVSASAPDGTIMAIRHRQYPVYGLQFHPESAGTPHGRDILENFLRM", "output": "Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia (By similarity)."}]}
+{"id": "function_test_1958", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSFTDKQEALVNSSYEAFKQNLSGYSVFFYTVILEKAPAAKGLFSFLKDSAGVQDSPQLQAHAEKVFGLVRDSASQLRATGGVVLGDAALGAIHIQKGVVDPHFVVVKEALLKTIKEAAGDKWSEELSTAWEVAYDALATEIKKAMS", "output": "Provides oxygen to the bacteroids. This role is essential for symbiotic nitrogen fixation."}]}
+{"id": "function_test_1959", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSIILIGFMGAGKSTVAKLLAEEFTDLDKLIEEEIEMPIATFFELFGEADFRKIENEVFELAVQKDIIIATGGGIIENPKNLNVLDRASRVVFLTADFDTLWKRISMDWQNVRPLAQDKEAAQLLFEKRMKDYSLVADLTIDVTDKSPEQIAEQIREKWEIE", "output": "Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate."}]}
+{"id": "function_test_1960", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MASRIADSLFAFTGPQQCLPRAPKLASARLSPGVYAVRPIDLLLKGTRRTFLVPAKKRIGCIKAVFVPVAPPSADNAEDREQLAESYGFKQIGQDLPDNVTLKDIMDTLPKEVFEIDDVKAWKSVLISVTSYALGLFMIAKAPWYLLPLAWAWTGTAVTGFFVIGHDCAHKSFSKNKLVEDIVGTLAFLPLVYPYEPWRFKHDRHHAKTNMLVHDTAWQPVPPEEFDSSPVLRKAIIFGYGPIRPWLSIAHWVNWHFNLRKFRPSEVNRVKISLACVFAFMAVGWPLIIYKVGVLGWVKFWLMPWLGYHFWMSTFTMVHHTAPHIPFKPADEWNAAQAQLNGTVHCDYPSWIEILCHDINVHIPHHISPRIPSYNLRAAHQSIQENWGKYTNLATWNWRLMKTIMTVCHVYDKEENYIPFDRLAPEESQPITFLKKAMPDYAA", "output": "Chloroplast omega-6 fatty acid desaturase introduces the second double bond in the biosynthesis of 16:3 and 18:3 fatty acids, important constituents of plant membranes. It is thought to use ferredoxin as an electron donor and to act on fatty acids esterified to galactolipids, sulfolipids and phosphatidylglycerol."}]}
+{"id": "function_test_1961", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEQTYQYAWIIPFLPLPVPMLIGLGLLLFPTATKSLRRMWAFQSVLLLSIVMIFSMNLSIQQINSSSVYQYVWSWIINNDFSLEFGYLIDPLTSIMSILITTVGILVLIYSDNYMSHDHGYLRFFAYMSFFSTSMLGLVTSSNLIQIYIFWELVGMCSYLLIGFWFTRPVAAKACQKAFVTNRVGDFGLLLGILGFYWITGSFEFRDLFQIFNNLISTNQVNFLFVTLCAVLLFAGAIAKSAQFPLHVWLPDAMEGPTPISALIHAATMVAAGIFLVARLLPLFIVIPHIMNFISLIGIITVFLGATLALAQKDINRGLAYSTMSQLGYMMLALGMGSYRSALFHLITHAYSKALLFLGSGSVIHSMETLVGYCPKKSQNMVLMGGLTKHVPITKNSFLLGTLSLCGIPPLACFWSKDEILNDSWLYSPIFAIIAWSTAGLTAFYMCRIYLLTFEGHLNVHFQNYSGKRNTPLYSISLWGKEGSKISNKNFRLVTLLKMNKTGRPSFFSNRVYKIDENVRNMTPPFLSIPNFGNIKTSLYPYESDNTMLFPILILFIFTLFVGFLGIPLNQDVDILTKWLTPSINLLHKNSNNSIDWYEFCKDALFSVSIASFGIFIAFFLYKPVYSSFQNLDLINSFFKMGPRRNFYDKIKNAIYDWSYNRGYIDAFYGTFFIVGTRKLAEFTHFFDRRIIDGIPNGVGLISFFVAEVIKSVGGGRISSYLFFYFSYVSIFLVIYYFLNL", "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity)."}]}
+{"id": "function_test_1962", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSKLIKGIAASDGVAIAKAYLLVEPDLTFDKNEKVTDVEGEVAKFNSAIEASKVELTKIRNNAEVQLGADKAAIFDAHLLVLDDPELIQPIQDKIKNENANAATALTDVTTQFVTIFESMDNEYMKERAADIRDVSKRVLSHILGVELPNPSMIDESVVIVGNDLTPSDTAQLNKEFVQGFATNIGGRTSHSAIMSRSLEIPAIVGTKSITQEVKQGDMIIVDGLNGDVIVNPTEDELIAYQDKRERYFADKKELQKLRDADTVTVDGVHAELAANIGTPNDLPGVIENGAQGIGLYRTEFLYMGRDQMPTEEEQFEAYKEVLEAMGGKRVVVRTLDIGGDKELSYLNLPEEMNPFLGYRAIRLCLAQQDIFRPQLRALLRASVYGKLNIMFPMVATINEFREAKAILLEEKENLKNEGHDISDDIELGIMVEIPATAALADVFAKEVDFFSIGTNDLIQYTLAADRMSERVSYLYQPYNPSILRLVKQVIEASHKEGKWTGMCGEMAGDETAIPLLLGLGLDEFSMSATSILKARRQINGLSKNEMTELANRAVDCATQEEVIELVNNYVK", "output": "General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)."}]}
+{"id": "function_test_1963", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGFKVETNGGDGSLVSAKVPPLANPLAEKPDEIASNISYHAQYTPHFSPFKFQLQQAYYATAESVRDRLIQQWNETYLHFHKVDPKQTYYLSMEFLQGRALTNAIGNLNIQDAYADALRKFGLELEEITEQEKDAALGNGGLGRLASCFLDSMATLNLPAWGYGLRYRYGLFKQIITKEGQEEVAEDWLEKFSPWEIVRHDVLYPIRFFGQVEVNPDGSRQWIGGEVIQALAYDVPIPGYQTKNTISLRLWEAKACADDFDLFLFNDGQLESASVLHSRAQQICSVLYPGDATEGGKLLRLKQQYFLCSASLQDIISRFKERRQGPWNWSEFPTKVAVQLNDTHPTLSIPELMRLLMDDEGLGWDEAWAVTSKTVAYTNHTVLPEALEKWSQPVMWKLLPRHMEIIEEIDRRFVALISKTRLDLEDEVSNMRILDNNLQKPVVRMANLCVVSSHTVNGVAQLHSDILKSELFASYVSIWPTKFQNKTNGITPRRWINFCSPELSRIITKWLKTDKWVTNLDLLTGLREFADNEDLQAEWLSAKRANKQRLAQYVLQVTGENIDPDSLFDIQVKRIHEYKRQLLNILGVIYRYKKLKEMSPEERKSTTARTVMIGGKAFATYTNAKRIVKLVDDVGSVVNSDPEVNSYLKVVFVPNYNVSVAEVLIPGSELSQHISTAGMEASGTSNMKFALNRVLIIGTLDGANVEIREEIGEENFFLFGATADEVPRLRKERENGLFKPDPRFEEAKKFIRSGVFGSYDYNPLLDSLEGNSGYGRGDYFLVGYDFPSYMDAQEKVDEAYRDKKRWLKMSILSTAGSGKFSSDRTIAQYAKEIWNIEECRVP", "output": "Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.; "}]}
+{"id": "function_test_1964", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSAELIAVYKDEQIIDLESAKVLGLSDGIKALNGTEPIYFDDSPLALEVIRHSCAHLLAQSLKALYPDAKFFVGPVVEEGFYYDFKTSSKISEEDLPKIEAKMKEFAKLKLAITKETLTREQALERFKGDELKHAVMSKIGGDAFGVYQQGEFEDLCKGPHLPNTRFLNHFKLTKLAGAYLGGDENNEMLIRIYGIAFATKEGLKDYLFQIEEAKKRDHRKLGVELGLFSFDDEIGAGLPLWLPKGARLRKRIEDLLSQALLLRGYEPVKGPEILKSDVWKISGHYDNYKENMYFTTIDEQEYGIKPMNCVGHIKVYQSALHSYRDLPLRFYEYGVVHRHEKSGVLHGLLRVREFTQDDAHIFCSFEQIQSEVSAILDFTHKIMQAFDFSYEMELSTRPAKSIGDDKVWEKATNALKEALKEHRIDYKIDEGGGAFYGPKIDIKITDALKRKWQCGTIQVDMNLPERFKLAFTNEYNHAEQPVMIHRAILGSFERFIAILSEHFGGNFPFFVAPTQIALIPINEEHHVFALKLKEALKKRDIFVEVLDKNDSLNKKVRLAEKQKIPMILVLGNEEVETEILSIRDREKQDQYKMPLKEFLNMVESKMQEVSF", "output": "Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr)."}]}
+{"id": "function_test_1965", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFKNYIEITKPGIIIGNSTLITGGFLFASRHAAFNYVLFIYTILGASLVIASACVFNNLIDIDIDKKMKRTSNRVLSKKLLPVFSVFNFAIFLGVLGLSILGCLVNFISMSLAVFGFFIYVVLYTMFYKRRSFYSTFIGSFSGSTPSVIGYTAVSNTIDICSILLFVIVIFWQMSHFYSISIMRIKDYREAKIPVFSVVKGVAITKKHIFFYVLNFSFFSSLFTFLGYLSYNFLLLSSIVNFYWSFLSYSNIKKNNDKKNARKLFYFSIIVIVFFNFLISIDVFF", "output": "Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group."}]}
+{"id": "function_test_1966", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MASISSLGVGSGLDLSSILDSLTAAQKATLTPISNQQSSFTAKLSAYGTLKSALTTFQTANTALSKADLFSATSSTTAFSATTAGNAIAGKYTISVTHLAQAQTLTTRTTRDDTKTAIATSDSKLTIQQGGDKDPITIDISAANSSLSGIRDAINNAKAGVSASIINVGNGDYRLSVTSNDTGLDNAMTLSVSGDDALQSFMGYDASASSNGMEVSVAAQNAQLTVNNVAIENSSNTISDALENITLNLNDVTTGNQTLTITQDTSKAQTAIKDWVNAYNSLIDTFSSLTKYTAVDAGADSQSSSNGALLGDSTLRTIQTQLKSMLSNTVSSSSYKTLAQIGITTDPSDGKLELDADKLTAALKKDASGVGALIVGDGKKTGITTTIGSNLTSWLSTTGIIKAATDGVSKTLNKLTKDYNAASDRIDAQVARYKEQFTQLDVLMTSLNSTSSYLTQQFENNSNSK", "output": "Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end (By similarity)."}]}
+{"id": "function_test_1967", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSDSLHTPEEPRPGPGEQLAHAHDGSLRHTRAKGEPRFPDGPKADPAGSHFERRIRSFQPRRSRVTAGQADALQRLWPKWGLDIDGHALDLTELFGNTHPVVLEIGFGMGEATARMAAEDPDTGILAVDVHTPGQGNLLNLADQHGLTNIRVANGDAIILLREMLPPDSLDGLRVYFPDPWPKKRHHKRRLIQPEFLTLAATRLRPGALVHCATDWEPYAEQMLDVLTAHPDFENTQPTGGYAPRPGFRPLTRFEGQGLDKGHVVNDLLFRRVQPRDQHRDLPPSATEAD", "output": "Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA."}]}
+{"id": "function_test_1968", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIAIIDYNAGNLRSIEKALELYTKNIVVTSDPETILSADKLVLPGVGNFGDSMKNISQKTGDCSLNEIINKCVQKVPFLGICLGMQLLLEKSEECPETPGLGVIKGDVIKFKHSEKIPHMGWNTVNQVQDIPLFEGIANNEYFYFVHSYHVNPSEKDVISGTTNYGYEFPCILNKKNVYATQFHPEKSGKNGLKMIENFVELI", "output": "IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)."}]}
+{"id": "function_test_1969", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MHMPKGFLSFGINIGIKDDTKDFGVIYSEIPCKATAVFTKNNFPGAPVIVGKEHVRSGVLQAIVINSKNSNVATGEKGIQNSREICKIIGESLDIKETLVLPSSTGVIGVPLKMEIILPACKKAKSLLKPGNLEEVAEAIMTTDTRKKISSRNIKTKSGQGTIYGIAKGAGMIEPNMATMLCYILSDVSLPEGTDLYSILKSSVDQSFNCLTIDSDTSTSDTVALLCNGLSGESSVQDFSKALTEICIDLTKLIATDGEGATKLIELTISGAKSEAQARKIGKSILNSPLVKTAIYGGDPNWGRLIMAVGKVFDEPIPFEGLQIYFGTLPVKEANPETLKKLSEYLKNNTEISLNVVLNVGTISMKFWGCDFTEKYIEENAYYTT", "output": "Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate."}]}
+{"id": "function_test_1970", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTRVFHPALSGPEQSRYQITDVASVSRSGLCINESPIRDRCGRTMGDLRLSVIDQCNLRCRYCMPEAEYAWLPRADLLSVDEISLIVDAFIAVGVDKIRLTGGEPLIRSDLAAIIEVISAKVGDGSGLQDLAITTNGVLLADQARKLKSAGMRRITISLDTLRPDRFKAISQRGTHYKVIEGIEAVAAAGFTDTKLDSVVIRGFNDDELSDLIEFARNVNAEVRFIEYMDVGGATQWSMDKVFTKAQMLSTLGKKYGPIAALPKYDSAPANRYRLPDGTTFGIIASTTEPFCATCDRSRLTADGIWLHCLYALSGINLRESVRAGASANDVVQILQRGWRDRANRGAEQRLAQRTRQVFLPVSRLKRDPHLEMHTRGG", "output": "Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate."}]}
+{"id": "function_test_1971", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKVVKSKEEIRAFAENWLGKRLVTYQTDANGQPVNQILVEAATDIGKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQGRELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGADGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDNVKAVLVNIFGGIVRCDLIADGIIGAVEEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKSLTDAAQQVVAAVEGK", "output": "Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit."}]}
+{"id": "function_test_1972", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGKFQVISHPLIQHKLSILRRTTTSTKDFRELVDEIAMLMGYEVSRDLPLEDVEIQTPVATTVQKQLAGKKLAIVPILRAGIGMVDGFLSLVPAAKVGHIGMYRDEETFQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGAASIKFVCLVAAPEGVAALQEAHPDVDIYTAALDEKLNEHGYIVPGLGDAGDRLFGTK", "output": "Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate."}]}
+{"id": "function_test_1973", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "DGYIRRRDGCKVSCLFGNEGCDKECKAYGGSYGYCWTWGLACWCEGLPDDKTWKSETNTCG", "output": "Depressant insect beta-toxins cause a transient contraction paralysis followed by a slow flaccid paralysis. They bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. This toxin is active only on insects."}]}
+{"id": "function_test_1974", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "FRGLAKLLKIGLKSFARVLKKVLPKAAKAGKALAKSMADENAIRQQNQ", "output": "Disrupts cell membranes, particularly those rich in phosphocholine, through formation of pores. Has antimicrobial activity against Gram-negative bacterium E.coli, Gram-positive bacteria B.subtilis and S.aureus, and hemolytic activity against sheep, pig and guinea pig erythrocytes. Has insecticidal activity against S.frugiperda ovarian cells by opening non-selective ion channels. Enhances the insecticidal activity of spider venom neurotoxic peptides."}]}
+{"id": "function_test_1975", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "GSSGMIPFPRV", "output": "Mediates visceral muscle contractile activity (myotropic activity)."}]}
+{"id": "function_test_1976", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "GTIPCGESCVFIPCLTSALGCSCKSKVCYKN", "output": "Probably participates in a plant defense mechanism."}]}
+{"id": "function_test_1977", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGMMSSLPFLLGGGESIRLTASDLTKKNLLHLNPEGRGIMQKLSVRLCTSLYSAKT", "output": "Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly (By similarity)."}]}
+{"id": "function_test_1978", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "VATSEQFNKTFIELVIVVD", "output": "Catalytic subunit of coagulation factor X-activating enzyme, a zinc-protease enzyme that acts in hemostasis. Activates coagulation factor X (F10) by cleaving the Arg-Ile bond at position 234 and is also able to activate coagulation factor IX (F9) and protein C (PROC) by specific cleavage of Arg-Ile and Arg-Val bonds (By similarity)."}]}
+{"id": "function_test_1979", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPAYNIVVFAGDHWGPEVTAEAIKVLRVIEKSRDDITLNLQDHLLGGASIDATANPLTDEALAAAKNADAVLLGAIGGPKWGTGAVRPEQGLLNVRKEMGTFGNLRPCNFAAPSLVEHSPLKASVCEGVDFNIIRELTGGIYFGDRKKMTAAATMDTEPYSRAEIERITPRAHLALQHNPPLPVWSLDKANVLATSRLWRKTVTEIMAKEFPQLKIEHQLIDSAAMIMVKNPRQLNGIIVTSNLFGDIISDEASVIPGSLGLLPSASLSGIPDGKGRVNGIYEPIHGSAPDIAGKGIVNPVAAILSVAMMMQYSFGRFDEARAIEAAVRNVLESGVRTGDIGGKATTSEVGDAVAAELEKLLK", "output": "Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate."}]}
+{"id": "function_test_1980", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVREEVAGSTQTLQWKCVESRVDSKRLYYGRFILSPLRKGQADTVGIALRRALLGEIEGTCITRAKFGSVPHEYSTIAGIEESVQEILLNLKEIVLRSNLYGVRDASICVKGPRYITAQDIILPPSVEIVDTAQPIANLTEPIDFCIDLQIKRDRGYQTELRKNYQDGSYPIDAVSMPVRNVNYSIFSCGNGNEKHEILFLEIWTNGSLTPKEALYEASRNLIDLFLPFLHAEEEGASFEENKNRFTPPLFTFQKRLTNLKKNKKGIPLNCIFIDQLELTSRTYNCLKRANIHTLLDLLSKTEEDLLRIDSFRMEDRKHIWDTLEKHLPIDLLKNKLSF", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_1981", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSSASPLARCCDEATPSAGPRAAQPPYHGPVTSMVAHDAAAGVTGEGAGPPVRRAPARTYQVRTYGCQMNVHDSERLAGLLEAAGYRRATDGSEADVVVFNTCAVRENADNRLYGNLSHLAPRKRANPDMQIAVGGCLAQKDRDAVLRRAPWVDVVFGTHNIGSLPTLLERARHNKVAQVEIAEALQQFPSSLPSSRESAYAAWVSISVGCNNSCTFCIVPSLRGREVDRSPADILAEVRSLVNDGVLEVTLLGQNVNAYGVSFADPALPRNRGAFAELLRACGDIDGLERVRFTSPHPAEFTDDVIEAMAQTRNVCPALHMPLQSGSDRILRAMRRSYRAERYLGIIERVRAAIPHAAITTDLIVGFPGETEEDFAATLDVVRRARFAAAFTFQYSKRPGTPAAQLDGQLPKAVVQERYERLIALQEQISLEANRALVGQAVEVLVATGEGRKDTVTARMSGRARDGRLVHFTAGQPRVRPGDVITTKVTEAAPHHLIADAGVLTHRRTRAGDAHTAGQPGRAVGLGMPGVGLPVSAAKPGGCR", "output": "Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine."}]}
+{"id": "function_test_1982", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIVIVDYDTGNTRNVKKALDYLGVNNQLSADPAIIMAASGLILPGVGAFKEAMKALNQRQLVPVIQAFAATGKPLLGICLGMQLLFDRSFEFGETAGLGLIPGEVVAIPTDSGLAVPHMGWNTNSLTQPDLFAAVFADQATYFVHSFYATTLPQFTLATTDYGQPLTSIVRRNNVLGTQFHPEKSGAIGLAGLKKFKEMTEDEALSRD", "output": "IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF."}]}
+{"id": "function_test_1983", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEYSEIMVRYGELSTKGKNKKDFIKQLGQNTRKALHQFDGIEVKAQHDRLHVTLNGADSTAVMDRLKGVFGIENFSPSVKVEKDIAAIKATALAMVQEIFTPGMTFKINTRRQDKQFEYDTNHLNDLLGGYILENVPGIQVKMKQPDLTLRVEVRLNGVFLSGQTIQGAGGLPVGTGGKAVMMLSGGIDSPVAAYYGMRRGVKLDMVHFFSPPYTSEQALAKAKELTARLAGYSGSIQFIQVPFTKIQETIKEKVPEGYLMTIQRRLMLRLAAAVAERRHAKGIFNGESLGQVASQTLESMAAINDVTSMPILRPLLSMDKTEIIKVAENIDTYDLSILPYEDCCTIFTPPAPKTHPDLEKSRKYEKYIDVDGLMQEALDGMIITDIHPDDNYLNQNEDVFAELL", "output": "Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS."}]}
+{"id": "function_test_1984", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELETAYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHPTYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDITVRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQEASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVVIKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPVQLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIPTNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFAANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGSKASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFAAEGSEILLRELKETGVNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVVVGADAGSKLQKAQELGIQVRDEAWLESL", "output": "DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA."}]}
+{"id": "function_test_1985", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKFPESLKGLKILVLGGGISGNSALDFLISEEAQPILCDRNQPETISVPFFHDNIDPRSFFEISLIIKSPGILPTHPILSYAVEKKIPVFSEIDLGRFFFKGKIIGITGTDGKSTTTSLVAHLLKKDFSDLKEGGNLGIPFTSFCKEPISLAVLELSSYQLEDSSPLDLNVSVFLNLAPDHLERHETMENYFRAKLKIADLQNPNHSLIVSEKIREKILNSTSVQCKLLSFGRATTSEAILDESSSEIRTSKFIYDISRFYLPGTHNRENLAAAILASEAIGGKPESIQAQIPFFMGLPHRFQIAGEKRGISFINDSKSTNLHSMLAGMSAWKNLDRTCLILGGRPKQEDPKPLYDFLMRGIGCVVLIGEARSVWEKGIRNVIGEKLFSVENLDEAFKIFKKWNVISESPEIRKIRLSSEITISYFVFSPACVSFDQYKNFEERGNHFLSLVEDFLNNASWT", "output": "Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)."}]}
+{"id": "function_test_1986", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNSSSIQRKILVTSALPYANGPIHLGHVLEGIQTDIWVRFQKAIGNECYFFCADDTHGTPVMLAARKEKITPEQLIERVGQEHYTDLTSFGINYDNYDSTHSKANQEISKDIYLKLKEKGHISKRSIEQAYCEKDRMFLPDRFIKGTCPNCNSKNQYGDNCEVCGATYNPKDLIDSHCTLCGTPPVVKNSDHIFFKLGNFHKKTEQSNVDFDLQSWIETSEAVSESEGVKKKLKEWFDAGLQDWDISRDGPYFGFEIPSEKNKYFYVWLDAPVGYMASSKNFFEKNFPNEPNKFDSFWKDKNSEIVHFIGKDILYFHTLFWPAMLEGSGYRSPSKIHVHGFIGVNGEKMSKSRGTFIKAKTFAKFLDAEHLRFYLAAKLGPGMDDIDLSFDDFVNKVNADLVGNLINSVSRVSTTILDTLDRTLGTVSEEGLALLEEILTQPVKTGTRDDSIQNIIKTAYEQRNYAKVMREITRLGDRVNRYVNDNAPWKLIKENPEKAREIVTAVLNASRFLAIYLYPVVPKISEQIYKLLNLKGSPEFKDLDKSRILEKTKINPYEMITKRVDEKAIKVMLEENKQSEHPKKEEIPKSSNKEEGIEISIEELSKVELRVGEIVEAKPVEGADKLVNVKVDLGELGIKNVFAGIKIAYQPENLKGLKVVVVANLKPRKMKFGISEAMLLASGEGESLSLFVPHKDAKPGDRLK", "output": "Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation."}]}
+{"id": "function_test_1987", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSGTGQSHAADAAPDSDPGQAAVALAYQHFEPRAYLRNNYAPPRGDLSSPDGVGPWKLRCLAQTFATGEVSGRALIDIGSGPTIYQLLSACAHFEDITMTDFLEVNRQELGLWLREEPGAFDWSVYSQHVCLIEGKGESCQEKERQLRARVKRILPIDVHQPQPLGTGSLAPLPADALVSAFCLEAVSPDLASFQRALDHITTLLRSGGHLLLIGALEESWYLAGEARLAVVPVCEEEVREALARSGYEVRDLRTYVMPAHLRTGVDDVKGIFFAWAQKKVGV", "output": "Catalyzes the transmethylation of nonepinephrine (noradrenaline) to form epinephrine (adrenaline), using S-adenosyl-L-methionine as the methyl donor. Other substrates include phenylethanolamine, octopamine and normetanephrine (By similarity)."}]}
+{"id": "function_test_1988", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "GTSQADVALLVVPADQGGFEGAFSKEGQTREHALLAFTLGVKQMIVGINKMDATTPDKYSETRFNEIQAEVSRYLKTVGYNPEKVPFVPISGFMGDNMVERSSNMPWYKGKILVEALDNVEPPKRPSDKPLRLPLQDVYKIGGIGTVPVGRVETGILKPGMVVCFAPTGLQTEVKSVEMHHTQLEQAVPGDNVGFNVKNVSVKDVKRGHVASDSKNDPAKAAASFQAQVIVLHHPGQINPGYSPVVDCHTAHIACKFAVLEKRLDRRSGKALEDDPKFIKTGDAAIIKMEPSKPMCVESFIEYPPLGRFAVRDMKQTVAVGVIKGVEKKEAGGKVTKSAQKATGKK", "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."}]}
+{"id": "function_test_1989", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSDVVSVGFVPMSTSAKGLLVVFCDETLASGPDSRKALGTAVDAVKRAAETSRFKGKSGAALDILAPEGLKASRLVVIGIGKPADLKEHDFLKLGGTIASKLGSGKEAVTVIAELPAGPMSPAQAAALAAGVRLRAYKFDRYKTKKKDDDAPLDASVAIAVRDVAATKKAFAPQNGLVDGVNIARELVNEPPNVLYPAEFARRASQLSKLGVGIEVLDVPAMTKLKMGALLGVAQGSARPARTVIMRWNGGKKGAAPIAFVGKGVCFDTGGISIKPSASMEDMKGDMGGAACVVGLMHALAARKAKVNVIGAIGLVENMPDGNAQRPGDIVTSMSGQTIEIINTDAEGRLVLADVLWYVAKKHKPKFMVDLATLTGAIMVALGTEYAGLFSNNDELATRLNEVGLATGERVWRMPLGPEYDKQIDSQFADMKNTGSRNGGSITAAQFLQRFVDDTPWAHLDIAGTAMASPKSDINQSWGSGYGVRLLDRLVATHYESK", "output": "Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides."}]}
+{"id": "function_test_1990", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTAITRITLTGALLAAALLLAALQPARAETLDRIVAVVDDQVVLASELERELATIANQLRSRGQRLPPRDVFQRQVLERLITQRVQLSRAQRVGITVDDATLDAAMQRMARQNNMTLGQFRQAVEQEGFEYNYFREGIREEIAISRLRQAQVEEQVTVTPQEVEEVLETLDDENQEYRLGHILVATPEAASTAQLEEARERIEQLREQIIAGETDFEGAATAFSDAASAMEGGDLGWRLHSQLPSLFAEAIDEGLQAGEVSGVLQNSSGFHLVKLMDQRTQGGERVTETRARHILIRTDGDVITDEDARLRLRSLLERIEAGESFAELAEAYSEDPGSAARGGDLGWTQPGQLVPEFQGAMDALEEGQISAPFASPFGWHIVQVTDRRERDVSRERLRDQLAQQIHQRKVEEAFEQWIRRLRDEAYVDVRVEL", "output": "Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation."}]}
+{"id": "function_test_1991", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNVIEKASEGLSRTYEIVIPADDLQARLAAKIEEIRPEVRLKGFRPGKVPTSHIRKMFGESIMGDLLNELVPDTTQKTLDEKKLRPASQPDISVTSEAKDVLAGKADFVFEIALEIMPDFEPADPAKLSVTRPVAEVEDAEVDEALERLANESREFAAKKGGKNAKAEDGDVVVIDFVGKLDGEVFEGGSAEDARVAIGDGAFIPGFEEQLLGAKVGEERELNVTFPEDYQAAQLAGKAAVFDVTVKGLESPQEAKVDDELAKRLGLENLDGLKDALKKRFAGEHGQQSRMKVKRDLLDKLDAEHKFDLPPKMVGAEFDNIWREVAHAIEQDQLEDEDKNKSEDELKSEYREIAERRVRLGLVLAEIGRRNNIDVTQEELSRAINQEAVKYPGQERQVVEFYQKNPNAVAQMRAPIYEEKVVDYILELADVTETTVSKEALYADEDEAPAKPAKKAVAKKKAPAKKAAAKSDDKPAAKKAPAKKAPAKKAAAKDEAPAKKPAAKKKAPAKKAAAKKDA", "output": "Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase."}]}
+{"id": "function_test_1992", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTDSTRSLRNCLAPAKLNLFLHITGRRPNGYHDLQSVFQLLNWGDTLHFTLRDDGRVARVTDVPGVPEESDLVVRAANLLKAHTGTTAGVDIEIDKCLPMGAGLGGGSSDAATTLLALNRLWQLDLSRTELQSLAVKLGADVPFFVFGKNAFAEGIGEELAEVELPTRWFLVVTPRVHVPTAEIFSDELLTRNTKPVTIADFLAQQNSDAGWPDSFGRNDMQQVVTSKYAEVAQVVKWLYNVTPARMTGSGASVFAAFQSKHEAEAAKAQLPTGWNGAVAESLNEHPLFAFAS", "output": "Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol."}]}
+{"id": "function_test_1993", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MADSAHVPETLAGGFFSVGLAERDPELAAAINQEATRQQHQIELIASENIVSRAVLEAQGSILTNKYAEGYPGKRYYGGCEFVDIAEELAIERAKKLFNCGFANVQPNSGSQANQGVFQAVLKPGDTILGMSLAAGGHLTHGAKPNQSGKWFNAVQYGVRPEDHLIDFDEVERLARAHRPQMIIAGGSAYPRQIDFKRFREIADDVGAIFLVDMAHFAGLVAGGAHPNPLDHCHIATTTTHKTLRGPRGGMILTNDEALAKKINSAIFPGIQGGPLMHVIAGKAVAFGEALMPEFKTYVEQVVSNARAMAAACRTAGLDVVSDGTDTHLALIDLRPKGVTGRDAEAALERAYITCNKNGIPFDPAPPTVTSGIRVGSPAGTTRGFREEEFIQIGTWIGEIVDALANGNSDAVEARVREEVKALTARFPIYEGLGG", "output": "Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism."}]}
+{"id": "function_test_1994", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSAASNPIVLSSSPEHCAPRAAAPTTHDFNEAAAVPSRGSSPESILSPSSLCRLPTRSRYFQKESLSDEPRTENGPPRGPPSKTSERREKREKKVERSISEPAAGLDGVRPPLLPQKANAPKRASGSNKKRGKCSKSETSTNKTLTGRVAKSGSMGSQESDKTATDASQCGSLRQKSPKPSDDGGNNDLQLEAALKRRLDWTPTKDTSIELVDASQEGAKEGSSKGFGDLLAGYSFNNNLLFSKCTSNDTTAEESTEDSQNGDRASEAKRRTKQRTKKFTTLTARVTARYQSDDMHSRLQTENPDGFMESANGNMPKLKRKGTSRSKRQQPEVVILSPEEAVKSLNEQDLIFGTCSQLEREDSPTMIRDLQAAIHESEQNMASQPTNSLLQRAGGGSMSTSTVSRFRAPKSLWSVAARDLDGSLIDAEVVDLTESPSFKPSMANKQVTAGSIPENPPYEEKIRESDSISQPSKRIHNQDEAPKPEASEHTHLSMPNYNDFTDAVLSERVTEFGFKPLKNRRKMVELLEKCWETKYGPSLYINDTSDQQAGPASSTSRVASARLQVPEGQPSKTKESREATKPKTAAGSKRTTKSDANPCTAAGPTRERTKITASGTRLNKPSSITSYRDVEEIEDSEEEIIPSPNRLQNNFRISRSSKRTASLSVTDTSSSPSRMPLSAGLSGVDKRNPSDISDQITRAVRAQSSTRPGTRNCPTWHEKILMYDPIIIEDFTTWLNTEGLGLVREDREVNVGSVRQWCESRGICCCYRRLNRN", "output": "Regulatory subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA."}]}
+{"id": "function_test_1995", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRVLGIETSCDETGIAVYDDKLGLLSHALYSQVKLHADYGGVVPELASRDHVRKIVPLIRQALKNANTEIADLDGIAYTKGPGLIGALLVGACVGRSLAFAWNKPAIGVHHMEGHLLAPMLEDDAPEFPFVALLVSGGHSMLVKVDGIGLYEVLGESVDDAAGEAFDKTAKLMGLDYPGGPRLAKLAAKGEPAGYQFPRPMTDRPGLDFSFSGLKTFTANTIAAEPDDEQTRANIARAFEEAVVDTLAIKCRRALKQTGYNRLVIAGGVSANTRLRETLAEMMTSIGGRVYYPRGEFCTDNGAMIAFAGLQRLKAGQQEDLAVKGQPRWPLDTLPPVA", "output": "Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction."}]}
+{"id": "function_test_1996", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLKRSMNIADYDPVLWQAIQDENLRQEEHIELIASENYASPRVMEAQGCQFTNKYAEGYPGKRYYGGCEYADIVEQLAIDRAKALFGADYANVQPHSGSQANAAVYMALLNPGDTILGMSLAHGGHLTHGASVSFSGKIYKAEQYGITSEGLIDYDALRKQAHEVKPKMIVGGFSAYSQIVDWAKMREIADEVGAYLFVDMAHVAGLIAAGVYPSPMPHAHVVTTTTHKTLAGPRGGLILANGNEELYKKLNSAVFPAGQGGPLVHVIAAKAVCFKEALEPEFKTYQAQVVKNAKAMVEVFKQRGYNVVSNGTENHLFLVDLVSHGLTGKAADAALSRANITVNKNAVPNDPQKPFVTSGIRVGTPAVTRRGFNEEDVAELAGWMCDILDSMNKDNHEQVIADTKEKVLAICKRLPVYP", "output": "Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism."}]}
+{"id": "function_test_1997", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MQVTFLGTSSGVPTRGRNVSSVALRLPQRSELWLFDCGEGTQHQFLRCDLRLSQLRRVFITHMHGDHVFGLPGLLASLGLGSTSNGVDLYGPDPLDAYLQGVLRTSSTRIGYPLAIHRVREAAEQNTVVFEDDDLIVTAAPLNHRVPAYAYRAEQKPRAGRFDIDKARELQIPPGPVYAALKRGESVTLDDGRTIDGRTLCGPEQPGVSVVYCTDTVFCEAAVQLAQGADLLIHESTFSHAEADMAFKRQHSTSTMAAQTAAEAGVKQLALTHLSPRYAPGNAVTADDLVAEASAIFPNTILARDFLNVDVNPSK", "output": "Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA."}]}
+{"id": "function_test_1998", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLATRRLLGWSLPARVSVRFSGDTTAPKKTSFGSLKDEDRIFTNLYGRHDWRLKGSLSRGDWYKTKEILLKGPDWILGEIKTSGLRGRGGAGFPTGLKWSFMNKPSDGRPKYLVVNADEGEPGTCKDREILRHDPHKLVEGCLVGGRAMGARAAYIYIRGEFYNEASNLQVAIREAYEAGLIGKNACGSGYDFDVFVVRGAGAYICGEETALIESIEGKQGKPRLKPPFPADVGVFGCPTTVANVETVAVSPTICRRGGTWFAGFGRERNSGTKLFNISGHVNHPCTVEEEMSVPLKELIEKHAGGVTGGWDNLLAVIPGGSSTPLIPKSVCETVLMDFDALVQAQTGLGTAAVIVMDRSTDIVKAIARLIEFYKHESCGQCTPCREGVDWMNKVMARFVRGDARPAEIDSLWEISKQIEGHTICALGDGAAWPVQGLIRHFRPELEERMQRFAQQHQARQAAS", "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor."}]}
+{"id": "function_test_1999", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEERENSEEGDDGAGEEEEEDQGSGEDGGEVGAEREQEAELKDSLRPSVLDLQLALARLCEDEYQDQPSKMPVLGLQIKDHQFERSFSGNGKVPSPGKIVNELFKEAKEHGAIPIDDTSKSSGAFYRARTFTGRGYKLGDSSKREFEYMQGEDPFEQGQEIQILLKLWSNGFSLDDGELRSYSDPINAEFLESVKKGEIPVELQRLVHGGQVNLDMEDHQDQEYIKPRLKFKAFSGEGKKLGSVTPEIISTPSSPEEEHKRFLNAEVDLDEHVPTTKIQIRLADGTRLIQRFNLSHRIMDVRQFIIHARSDFAQCDFALLTTFPNVELTDETQTLEEADILNTVILQRLK", "output": "Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. Regulates the centrosomal levels of kinase aurka-a/Aurora A during mitotic progression by promoting aurka-a removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis."}]}
+{"id": "function_test_2000", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MFNKKNILITGGTGSFGKTYTKVLLENYKPNKIIIYSRDELKQFEMASVFNAPCMRYFIGDVRDKERLSAAMRDVDFVIHAAAMKHVPIAEYNPMECIKTNIHGAQNVIDACFENGVKKCIALSTDKACNPVNLYGATKLASDKLFVAANNIAGNKQTRFGVTRYGNVVGSRGSVVPFFKKLISEGAKELPITDTRMTRFWISLEDGVKFVLSNFERMHGGEIFIPKIPSMKITDLAHALAPNLSHKIIGIRAGEKLHEIMISSDDSHLTYEFENYYAISPSIKFVDKDNDFSINALGEKGQKVKDGFSYSSDNNPLWASEKELLEIINHTEGF", "output": "Catalyzes the first step in the biosynthesis of pseudaminic acid, a sialic-acid-like sugar that is used to modify flagellin. Has both C6 dehydratase and C5 epimerase activities that result in the production of both UDP-2-acetamido-2,6-dideoxy-beta-L-arabino-4-hexulose and UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-4-hexulose."}]}
+{"id": "function_test_2001", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTVTTSSPATAEGRTPGIGRVARVIGPVVDVEFAPDELPEIYQALEVDRTIGGETLTLTLEVAQHIGDNTVRAISMQQTDGLVRGAVVRDTGAPISVPVGDATKGHVFNVLGTPLDVDKVDAETRWSIHRQAPAFDQLESKTEMFTTGIKVIDLLAPYVRGGKIGLFGGAGVGKTVIIQEMIRRVAKEFGGVSVFAGVGERTREGNDLFLEMTEAGVIEDTALVFGQMDEPPGTRLRVALGALTMAEYFRDVQKQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGVLQERITSTRGHSITSLQAIYVPADDLTDPAPATTFTHLDAQTVLDRSISDLGIYPAVSPLDSNSRILDARYLGQEHYDTAREVQRILQRYKDLQDIIAILGIDELSEEDKILVNRARRIQRFLSQPFFVAEQFTNIPGKFVPLDETIDSFKRLSQGDYDHLPEQAFFMCGGIEDAEKNAENL", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits."}]}
+{"id": "function_test_2002", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEIDAVPMSDTPRKILVTSALPYANGPIHLGHLLEYIQTDIWVRFQKLRGQQCIYVCADDAHGTAIMLKAEENGVTPEQQIAQVKADHERDFADFQVNFDNYYSTHSPENRALSEMVFQRNKDAGYILEKTITQLYDPQKGMFLADRFVKGTCPKCKSEDQYGDNCEVCGATYTPAELIEPYSSVSGATPVEKETTQLFFDLPKFEALLREWTRSGALQEQVANKLQEWIEDLQPWDISREAPYFGFEIPGYPGKYFYVWLDAPIGYMASFQNYCDREGLSFDDYWGKESTAELYHFIGKDIINFHGLFWPAMLDGAGLRKPTAIYSHGFVTVNGAKMSKSRGTFIKARTYLDHLSPEYLRYYFAAKLSSRVDDFDLNLEDFAQRVNSDLVGKLVNIASRTGNFVKKFGGTLSTELDNMMLVREVQEAGPRIADFYEKREFGKAMREIMALADHANVYIADKAPWSLSKEEGKEQEVLAICSTAINVFRLLVIYLKPVLPALAERAEAFMQVEPLTWADSEQLLLGHEIAKFKPLLSRVDMAQVESMLEDSKESTPAPAAAKPKKAATQKADAADNDETISIDDFLKVKLRVARVAKAAHVDGADKLLQLTLDVGELGQRNVFAGIKARYAPEELEGKLVVLVANLAPRKMKFGISEGMVLAAGPGGDDIHILSPDSGAEPGMEVR", "output": "Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation."}]}
+{"id": "function_test_2003", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTEKPTIAFAKFAAPKKGSVILLVPEGGNLGQAATAADPAGVMPKVFAAAEFKGKLAATVEALAPQGTAYDRVAVIGTGNPSALTEQSWLQIGGAAAAAAKNAGEVTVIADVAGLELSAREAANIGLGILLRSYVFDKYKTRRDENGIKARDKKFTIQCADPNAAKKAFAEASALGDGVYLARDLVNEPANVLGPVEFAAQAKALESLGVKVDVLTEREMKKLGMGALLGVAQGSVRPPRLVVMQWNGGKPKQKPVAFVGKGVVFDTGGISIKPAASMEDMKGDMAGAAAVVGLMHALAARKAKTNAVGIIGLVENMPDGNAQRPGDIVTSMSGQTIEIINTDAEGRLVLADALWYCKEQFKPQFMVNLATLTGAIIVALGNSHAGLFSNDDTLSERLTAAGQATGEKVWRMPLGSEYDKLIDTKNADMKNTGGRQAGSITAAQFLKRFVDDTPWAHLDVAGTAMGSPSSEINQSWASGFGVRLLDRLVADHYEG", "output": "Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides."}]}
+{"id": "function_test_2004", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLDIYLGVGMFIAIVLALVLIIMFAKSKLVPEGEVTISINGDPDKAITAQPGDKLLGALANSGIFVSSACGGGGSCGQCRVDIKAGGGEILPTELDHISKREAKEGCRLSCQVSIKQDMDIELPEEIFGIKKWDCEVISNDNKATFIKELKLKIPNGESVPFRAGGYIQIEAPPHHVKYKDFDVPEEYRGDWERFGFFDIESKVDDETIRAYSMANYPEEEGIIMLNVRVASPPPNNLSLPAGKMSSYIWSLKEGDKATISGPFGEFFAKKTDAEMVFIGGGAGMAPMRSHIFDQLRRLKTDRKISFWYGARSLREMFYVEDFDMLQKENDNFKWHVALSDPQPEDNWEGMTGFIHQVLLENYLKDHPAPEDCEFYMCGPPMMNAAVISMLKDLGVEDENIMLDDFGG", "output": "NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway."}]}
+{"id": "function_test_2005", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MESAIAKTGPITALGAMSGTSLDGVDAAIVVTDGVAIDGFGASAYEPYSDAQRAVLAKALGQWQGADVEAATGVIEQVHRTVLARFQQARLIGFHGQTLAHAPHTQGTLQVGDGAWLATALDRPVIWDFRTRDVEMGGEGAPLAPFFHFACAKYIGATQPLAFLNLGGVGNLTYVDPSFARPEEVGALLAFDTGPANAPVNDLVQARLGLAYDRDGQVAREGTVCQRVLERALTAPYFARIPPKSLDRNDFSQIVDLVDTLPDADAVATLTALSAAAVSQGVRHCPQVPQQVLVTGGGRKNPVLMEMLQSMLACPVKPVEDVGLDGDMLEAQAFAYLGVRVARGLPTSCPGTTGVRAPVGGGRISYPGTAAMAAQTG", "output": "Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling."}]}
+{"id": "function_test_2006", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTQTLHIVGGGMAGSEAAWQAAEMGVDVVLHEMRPKVGTFAHQTGLLGEMVCSNSFRSDDDEQNAVGLLHWEMRAAGGLIMRMADKHRLPAGGALAVDRDLFAQSVTDTLTAHPRITIEYGEISELPASGQWIFATGPLTSSKLSDAIAAQTGGAALAFFDAIAPIVYFDSIDMSRAWMQSRYDKGETEEERTAYLNCPMDKDQYEAFIDALLAADKTEFKEGETADYFDGCLPIEVMAERGRETLRFGPMKPVGLTNPHQPDVKPYAVVQLRRDNKLGTLYNIVGFQTKMKYGAQAAVFKTIPGLENASFARLGGIHRNTFLNAPTLLDEQMRLRSRPNIRFAGQITGVEGYVESAAMGLLAGRLAAAEILGISLSAPADTTATGALITHISGGAEAKTFQPMNVNFGLFPPVEGLKGGRRGRKDRYKAYTDRAKRDWQNWLEAVKEPA", "output": "Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs."}]}
+{"id": "function_test_2007", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFNFINSLKNYSQESFRAARYIGQGFIVTLNHINRSAITVQYPYEKLITSERFRGRIHFEFDKCIVCEVCVRVCPINLPVVDWNFQQDIRKKKLKNYSIDFGVCIFCGNCVEYCPTNCLSMTEEYELSVYDRHELNYDQIALGRLPFNSFQDALVTKAS", "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_2008", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSPGSVLKTAPGAYLSGFGNEFATEAVPGALPEGQNSPQRAPFGLYAEQLSGSAFTAPRRENRRSWLYRLRPSANHPAFQPLAQGLLRSGPFDEVPASPNRLRWSPQPPPAQPTDFVDGLVTYAGNGDAASGAGISIHLYAANRSMVDRVFFDADGELLIVPQAGRLRLVTELGVLDVAPGEIAVVPRGVRFRAELPEGQAAGYVCENHGAFFRLPDLGPIGANGLANPRDFLTPVAAFEDVDRPTEVVQKFLGRLWSARYSYSPLDVVAWHGNLVPYKYDLARFNTINTVSFDHPDPSIFTVLTSPSEVPGTANCDFVIFPPRWMVAEHTFRPPWFHRNVMSEFMGLVHGVYDAKAGGFAPGGGSLHNCMSGHGPDRTSYEQAIQADLKPHKIKDTLAFMFESRWVIRPTRFAMETPALQQDYDACWAGFQKAKLP", "output": "Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate."}]}
+{"id": "function_test_2009", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRAHLITYGCQMNEYDTHLVESQLVSFGADIVSSVDEADFVLINTCAVRGKPVDKVRSLLGDLRKQKAQRPLVVGMMGCLAQLEEGQQIARKFEVDVLLGPGSLLDIGKALETNERFWGLQFKDELHGHIPPPPQGKLQAHLTIMRGCDHHCTYCIVPTTRGPQVSRHPDDILRELDLLLAAGVQEVTLLGQNVNAYGVDQGARLAGYPSFANLLRLVGRSGIRRVKFTTSHPMNFTEDVAAAMAETPAVCEYVHLPVQSGSNRVLRRMAREYTREKYLSHIAEIRRHLPDVVLATDIIVGFPGETEEDFQETLSLYDEVGYDAAYMFIYSARPGTPSYKHFADLPREVKTERLQRLIAKQKEWSARKNAAKVGTIQEVLLRGDAHDAHFLEGHTRGNHPTVVPKAAGASGPGIYRARIEHATPHMLYGRLIGEDGQDLPELPRFNPEAAGLSHPLQMV", "output": "Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine."}]}
+{"id": "function_test_2010", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRVFSSIDELRHTLDALRRQGRTVGLVPTMGYLHAGHMELVSRARAENDIVVVSIFVNPLQFGPAEDLSKYPRDLERDAAMLRQAGVNFLFSPGVEDMYSRPMLTVVDVPDLGRELEGAVRPGHFAGVATVVCKLFNIVQPQTAYFGAKDYQQVVIIKRMVDDLALPVRLISVPTVRDSDGLALSSRNVYLSEAERRAAVIVPQTLDEAERLVADGLTDPVELEARLTAFLSREPLAKPEVVAVRDAATLQPVTSIADPVVVALFVRVGSTRLLDNRVVGSNRFVGNNRVAGGQSLPGKGVTR", "output": "Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate."}]}
+{"id": "function_test_2011", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MADSHGNAKGATAHTEAGGGHKAPFPPFQKDTFASQLVSLTIAFVALYLISSRLALPRVRKTIDDRQNKIEGDIAQAQTLKNESDAALKAYEVELAAARTRAQAIGNETREKLNAEADTERKALEKRLSAKLADAEKTIASTRTAAMSNVRGIASDAATAIVQQLTGAMPDRKLVDSAVEASMKG", "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity).; "}]}
+{"id": "function_test_2012", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTVLIHVLGSDIPHHNRTVLRFFNDALAATSGHAREFMVAGKDDGLSDSCPALSVQFFPGKKSLAEAVIAKAKANRQQRFFFHGQFNPKLWLALLSGGIKPSQFFWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGELLYFPTRMDPSLNTMANDRQREGKMTILVGNSGDRSNEHIAALRAVHQQFGDTVKVVVPMGYPPNNEAYIEEVRQAGLELFSEENLQVLSEKLEFDAYLTLLRQCDLGYFIFARQQGIGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDIVREAQRQLASVDKNTIAFFSPNYLQGWQRALAIAAGEVA", "output": "Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis."}]}
+{"id": "function_test_2013", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGVHILSTGSSVPNFSVENQQFEDMIETSDHWISTRTGIKKRHLAPSSTSLTKLAAEAANKALYAANLKPTEISLIILATSTPDDLFGSASQLQAEIGATTPVAFDITAACSGFIVALVTAAQFIQLVYDNILVVGADTCLDGLIGQIELPVFYLVMVLEQLVLGQSLKNSILGFKLCTDGQLNSHLQLMNKPVNNQKFGGTEIPHGNYNSITMNGKEVYKFAVFQVPTVIRQCLNNLNISIDEVDWFILHQANTRIIEAIASRLSVPFSKMITNLEHYGNTSAASIPLALDEAIQSNKIQPGQIIVLSGFGAGLTWGAIVLKW", "output": "Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids."}]}
+{"id": "function_test_2014", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKRDYYEVLGVSKSADEQEIKKAYRKLARQYHPDVNPGDKDAEEKFKEATEAYDVLSDTEKRARYDQMGHSAFDPNQQGFGGFGGDFGGFGDIFDMFFGGGGGGGQRRQGPTRGNDLRYDLTITFEEAAFGTEKEIQVPRQETCTECHGSGSAPGTHPTTCSQCHGTGQVKATQRTPFGAIQTARTCPACNGSGQFISSPCKECSGKGTTRKVKTIKVTVPPGSEDGLNLRFSGNGEAGLRGGPSGDLYVVLNVKAHKFFEREGNDVYCEIPITFVQAALGSELDVPTLDGKVKMKIPEGTQTATVFRLRGHGIPYRRGNGRGDQHVRVVVATPTKLTDRQKELLREFGEVTSDQQQMGKKSFFEKVKENIRDAIDL", "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins."}]}
+{"id": "function_test_2015", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MREIVHIQAGQCGNQIGAKFWEIISDEHGIDATGAYHGDSDLQLERINVYYNEASGGKYVPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNIQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADEDAEFEEEQEAEVEEN", "output": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin."}]}
+{"id": "function_test_2016", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNGFSTEEDSRDGPPAQAAPFFGQTCCLIDGGERCPRPAGNASFSKRVQKSISQKKLKLDIDKSVRHLYICDFHKNYIQSVRNKRKRKTSDDGGDSPEHETDVPEVDLFQLQVNTLRRYKRYYKLQTRPGLNKAQLAETVSRHFRNIPVNEKETLAYFIYMVKSNRSRLDQKSESSKQLEA", "output": "Functions as transcription repressor, probably via its interaction with histone deacetylase complexes. Involved in the functional recruitment of the class 1 Sin3-histone deacetylase complex (HDAC) to the nucleolus. Binds DNA, apparently without sequence-specificity, and bends bound double-stranded DNA. Binds phosphoinositol phosphates (phosphoinositol 3-phosphate, phosphoinositol 4-phosphate and phosphoinositol 5-phosphate) via the same basic sequence motif that mediates DNA binding and nuclear import."}]}
+{"id": "function_test_2017", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTKTEKKLRHYITKAIADYKLLDKGDKAMLCLSGGKDSFGLLKVLHGLIEDKTYDIDLHVYTLDQSQPGWDDSQLRKYLDDLGVSYEIETKNTYGVVIDKVPEGKTYCSLCSRLRRGNIYRYAKEHKMDKIILGHHRDDLIQSLLMSILYQGQIKSMPPKFVTQDGENTVIRPMVLVQERDLIEFAKEENFPIIPCNLCGSQENLKRKKVKKLIQDLALENPKVPSNILNSLSNVLPSHLMDKNLLNSLEN", "output": "Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system."}]}
+{"id": "function_test_2018", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLKGHLHSVESLGTVDGPGLRYILFTQGCLLRCLYCHNPDTWKISEPSREVTVDEMVNEILPYKPYFDASGGGVTVSGGEPLLQMPFLEKLFAELKENGVHTCLDTSAGCANDTKAFQRHFEELQKHTDLILLDIKHIDNDKHIRLTGKPNTHILNFARKLSDMKQPVWIRHVLVPGYSDDKDDLIKLGEFINSLDNVEKFEILPYHQLGVHKWKTLGIAYELEDVEAPDDEAVKAAYRYVNFKGKIPVEL", "output": "Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine."}]}
+{"id": "function_test_2019", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MADLASRITKPSDEPVDAVAPAPTATTGEGNGTEEPVDDGVNKGLVETTYDVEVKLSGLQADDESLLYSGVASFEELGLAKSINDGLLAMNFKKPSKIQEKALPLMLSNPPRNMIAQSQSGTGKTAAFVLTVLSRVDLTKPTQPQALLLAPSRELARQIQSVIQTIGQFCENLNVEAAIPGSISRETGVRANVVVGTPGTVMDLIRRRQFDVSQLKIMVIDEADNMLDQQGMGDQCVRVKGMLPKDIQTLLFSATFPEKVMIFARKYATNAHEIKLRHTDLTVKGISQMYMDCPDESKKYDILCKLYGLMTIGSSVIFVRTRESASEIQRRMEADGHKVSALHGAHEGQNRDALLDDFRSGRSKVLITTNVLARGIDVSSVSMVINYDIPMKGPGDKEPDMETYLHRIGRTGRFGRVGVSISFVYDRKSYDALSKIADHYGLDLVQLAPDDWDATETKVQEVIKSSRARPDYVPNAGDK", "output": "ATP-dependent RNA helicase associated with the nuclear pore complex and essential for mRNA export from the nucleus. May participate in a terminal step of mRNA export through the removal of proteins that accompany mRNA through the nucleopore complex. May also be involved in early transcription (By similarity)."}]}
+{"id": "function_test_2020", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPDAVKVGFVPFSVAARGTLVVLCDDALKFGPATSKALGVAVSTVKRAVAASQFKGKSGSALDLLAPEGLKVGRLVVIGTGKAAALKDYDVLKLGGAIAGKIGAGDTAVTVIAELPGGAMKPEQAAAIASGILLRAYKFDRYKTKKKDDDANALNANVSIAVADAAAAKKAFAPDSAVVDGVILARELVNEPPNVLYPEEFAKRAAQLKKLGVDIQILDVKAMTQLKMGALLGVSQGSAHPGRTVIMRWNGGKRGEQPVAFVGKGVCFDTGGISIKPSASMEDMKGDMGGAACVVGLMHALAARKAKVNVIGAIGLVENMPDGNAQRPGDIVTSMSGQTIEIINTDAEGRLVLADVLWYVAQKHKPKFMVDLATLTGAIMVALGTDHAGLFSNNDELAERLTAVGVSTGEKVWRMPLGPEYDKQIDSQFADMKNTGSRNGGSITAAQFLQRFVDNTPWAHLDIAGTAMGAPKNDINQSWGSGYGVRLLNALVAEYYEAKK", "output": "Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides."}]}
+{"id": "function_test_2021", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPMIETRTDRMLLNFGPHHPSMHGVLRLLVTLDGENIVDCEPVIGYLHRGMEKIAENRTVVQYLPYVSRWDYGAGMFNEAITVNAVEKLAGIPVPRRASYLRVIMLELTRITNHLLWFGPFLADLGAQTPFLYAMREREWILDLFEAVTGMRLINNNYFRVGGVAVDLPYGWTEKCLDFCEYFLPKVDEYERLVTDNPIFRRRLEGIGVISKQDAINWGLSGPMLRACGVNWDLRKVDHYECYDDFDWEVAVYPEGDCLARYRVRMKEMRESCKIVQQAVKALPGGPFENLEAKRMLEGPKSEWNKGDYQFISKKPSANFKIPKGEAYVRVESAKGELGIYIVGDDNVCPWRWKIRPPGFVNLQVLPQLIRGMKVADMIAILGSIDIIMGEVDR", "output": "NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration."}]}
+{"id": "function_test_2022", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSKIKVLVVDDSAIVRKIFTEELSKYPDIEVVGSAPDPFVARDKIVHLKPDVITLDIEMPRMDGLTFLKKLMRHYPLPAIIVSSLTPKGGKLTLEAMDIGAVDAIAKPGSSYSVGDMSGQLVEKIRAASGARVVRKSTQEMFQPGSRLSIRSLAETSNKVIAIGASTGGTEALKNVLSRMPPDSPGILVVQHMPANFTTAFAERLNSLCQIGVKEAADNDSVTPGTALIAPGNYHMILRRSGARYYVQIKMGPMVHHQRPAVDVLFKSTAKYAGANAIGVILTGMGADGAAGLLEMKQMGAGTIAQNEKSCIVYGMPKEAVKIGAVDKIVHLDSIADEIVRMV", "output": "Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid."}]}
+{"id": "function_test_2023", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDLSEPIHDFLLVFLGSGLILGGLGVVLLPNPIYSAFSLGLVLVCTSLFYILSNSYFVAAAQLLIYVGAINVLIIFAVMFMNGSEYYKDFHLWTVGNGITSMVCISLFISLITTISDTSWYGIIWTTRSNQIIEQDFLSNSQQIGIHLSTDFFLPFELISIILLVALIGAIAVARQ", "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient (By similarity)."}]}
+{"id": "function_test_2024", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTPETLPIDQYEQQLAEKAARLRQMMLAFQAPEAQIFRSQPAHYRMRAEFRIWHDEDDLYHIMFDPQTKARIRIDHFMPGSPLINALMAEMMTAIRPEPLLRAKLFQIDYLTTQSGEAVVTLIYHRPLDDAWRECAAGLRDALRARGYHIQFIGRANKTKIYLDRDYVDERLTVAGRTLIYQQIENSFTQPNAGINVHMLEWALAATEGAQGDLLELYCGNGNFSLALARHFDRVLATEIAKLSVEAAHYNIAANHIDNVQIVRMSAEEFTQAMRKEREFTRLKEIDLQSYRCETIFVDPPRSGLDEATVSMVQAYPQILYISCNPDSLCRNLSTLSTTHTIERLALFDQFPYTHHMECGVLLVRKATAV", "output": "Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA)."}]}
+{"id": "function_test_2025", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKIKLANPRGFCAGVDRAIEIVNRALDVFGAPIYVRHEVVHNRFVVEGLRTRGAVFVDELDEVPDGALVIFSAHGVSQEVRQEADARGLKVFDATCPLVTKVHMEVMRYSRDGRECILIGHAGHPEVEGTMGQYDSANGGAIYLVEDEEDVGRLIVNDPGNLAYVTQTTLSVDDTARVIDALRQTFPEIKGPRKDDICYATQNRQDAVKELAATCDVVLVVGSVNSSNSNRLRELAERMQTPAYLIDGAHEIQPDWFAGAASVGVTAGASAPEVLVQQVVQRLRELGGEAPAEIAGREENIVFSMPKELRIPAVNQS", "output": "Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis."}]}
+{"id": "function_test_2026", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MENSLKSSGKPPAAPKVGMVSLGCPKALVDSEQIITQLRAEGYEISGTYDGADLVVVNTCGFIDEAVQESLDAIGEALAENGKVIVTGCLGAKKSASGSGLIEEVHPKVLAVTGPHAVGEVMQVVHSHLPKPHDPFVDLVPAAGIKLTPRHYAYLKISEGCNHRCSFCIIPSMRGDLVSRPVAEVMLEAENLFKAGVKELLVISQDTSAYGVDVKYRTGFWNGRPLKTRMTELVGALGELAAQYGAWVRLHYVYPYPHVDEIIPMMAQGPLKGHVLPYLDVPFQHAHPDVLKRMKRPANAEKVLERVQRWREICPDLTIRSTFIAGFPGETEAQFETLLDFIREAELDRVGCFAYSPVEGASANELDGALPDDVREARRARFMEVAEEVSAARIERKVGKTLKVLIDEVNEEGGIGRTAADAPEIDGVVYVEPAAKASKRYKVGDFVSVKITGADGHDLWGEV", "output": "Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12."}]}
+{"id": "function_test_2027", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSILSLVEDRPTPKEVYNWKIYLLAAVASCTSCMIGYDSAFIGTTISLQSFKDEFDWDSMSAAHQDLVSSNIVSLYQAGAFFGAFFAYPIGHFWGRKWGLMVSALIFTLGAGIMLGTNGDRGFGLLYGGRVLAGLGVGAGSNITPIYISELSPPAIRGRLVGVYELGWQIGGLVGFWICYGVDETLPPSHKQWIIPFAVQLIPSGLLIIGALFLKESPRWLFLRGRREEAIKNLCWIRQLPEDHVYMIEEIGAIDQTLEHQRATIGLGFWKPFAAAWTNKKILYRLFLGSMLFFWQNGSGINAINYYSPTVFKSIGVTGSNTSLFTTGIFGVVKTVVTFIWLLWLIDRVGRRLLLLIGAAGGSICLWIVGAYIKIARPSERENKQMDGGGIAAMFFFYLWTVFYTPSWNGTPWVINSEMFDPNIRSLAQACAAGSNWLWNFLISRFTPQMFAKMDYGVYFFFASLMILSIIFVFFLIPETKGIPLESMDRLFETQPIWRAHGTLLKQIREDEERFRHDLEDSGFVKSTDRQVEVVDA", "output": "Integral membrane transporter that imports quinic acid to be catabolized as a carbon source."}]}
+{"id": "function_test_2028", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTRTVHVIGGGLAGSEAAWQLAQADIPVILHEMRPVRTTPAHQTDGLAELVCSNSLRSDDADYNAVGLLHEEMRRAGSLILAQADAHKVPAGGALAVDRDGFSQGVQAALAGHPRITILREEVAGLPPEDWEQVVIATGPLTSPAMAEALRGMTGEDSLAFFDAIAPIVTKDSIDFGKAWFQSRYDKGTGSDYINCPLDREQYNTFIDALITGEKVDFHEWEKDTPYFEGCLPIEVMAERGKDTLAYGPMKPVGLTNPNGPKPFAVVQLRQDNALGTLYNLVGFQTKLRHGEQARIFRAIPGLENAEFARLGGLHRNTFINGPRVLDRTLRLKAQPRLRLAGQVTGCEGYVESSAIGLLAGLFAAAEALGRDMLRPPATTALGALLNHVTGDAEAETYQPMNINFGLFPPPPERDERGRRVKGRDRKKLYAQRAREALTPWLNTIRE", "output": "Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs."}]}
+{"id": "function_test_2029", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAAGRGERAGQSAEGPKQYRLIGAEAVLARTLRAFTDCPLIGTIAVVIHPDDHALYRRAVPEKHENVILVTGGPTRQESTRLGLLALKDEAPQYVLIHDGVRPFIGQDLLERIIANLTPDNGVLPALAVSDTLKRAAADGMVETTISRTGLFAAQTPQAFPYAPILDAHEKAFAINRTDFTDDAAIAEWQEIAVRIIEGSADNTKLTWAKDIEMADKRLRQDHAVFPDIRTGNGYDVHSFEPGDHVTLCGVKIPHEAKLNGHSDADVALHALTDALLATRGAGDIGTHFPPSDPQWKGAASRIFIEHAAKIVREAGGRIANVDVTLISEAPKIGPHRAAMTQALCDMLGIAADRVSIKATTNEKLGFVGRREGIAAIATATVIYPGEVPE", "output": "Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)."}]}
+{"id": "function_test_2030", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MHHVNKYFNQTMVIEALKMSFYKLNPKQLIKNPIMFVVEVGMILTLILICFPDIFGTSYLSRSYLITIFIILLITILFANFSEAFAEGRGKAQADSLRQAQSNLTARLIEENGAYRIVNATELKAGQNIRVENGETIPADGVVINGLATVDESAITGESAPVIKESGGDFDGVIGGTLVTSDWLEIRVESEAGTSFLDKMIALVEGAERNKTPNEIALFTLLTTLTIIFLVVIVTLYPIASYLHLILPIAMLIALTVCLIPTTIGGLLSAIGIAGMDRVTQFNVLAKSGRAVEVCGDVDVMILDKTGTITYGNRIASEFLPVNQQMWEKLIVAAYMSSIYDDTPEGKSIVRLAKQMYINELPKDIDGTYKPFTAETRMSGIITNEISVFKGAPNSMINLVKQQQGDIPLNIESICMDVSSKGGTPLIVIENNVMLGVIYLKDVIKDGLVERFAELRKMGIETVMCTGDNALTAATIAKEAGVDRFVAECKPEDKIKVIKDEQAKGHIVAMTGDGTNDAPALAQANIGLAMNSGTISAKEAANLIDLDSNPTKLIEVVKIGKQLLMTRGALTTFSLANDVAKYFAILPALMMSTIPEMTLLNIMHLSSPKSAIISALIFNALIIVALIPIAMKGVKVKGYSIDRIFINNMLIYGLGGLIVPFLGIKLIDMIVQFFV", "output": "Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm."}]}
+{"id": "function_test_2031", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNYLNKIRIENPLTICYTNDVVKNFTANGLLSIGASPAMSEAPEEAEEFYKVAQALLINIGTLTAQNEQDIIAIAQTANEAGLPIVFDPVAVGASTYRKQFCKLLLKSAKVSVIKGNASEILALIDDTATMKGTDSDAYLDAVAIAKKAYAIYKTAIVITGKEDVIVQGDKAIVLANGSPLLARVTGAGCLLGGIIAGFLFRETEPDIEALIEAVSVFNIAAEVAAENENCGGPGTFSPLLLDTLYHLNETTYQQRICIQEVE", "output": "Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)."}]}
+{"id": "function_test_2032", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSQQLTFKQLEKAQQGDSFDWEAVKKQVKYDDNGLIPAIAQQFDSKEVLMMAWMNEAALQETLETGRVCYWSRSRQSYWRKGEESGQIQLLKDLRFDCDGDAILLLVDQTGPACHTGRKSCFYTAIHDHQAKILTNPIIDPEALYKK", "output": "Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP."}]}
+{"id": "function_test_2033", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGQVLPLVTRQGDRIAIVSGLRTPFARQATAFHGIPAVDLGKMVVGELLARSEIPAEVIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVSRACATSFQAVANVAESLMAGTIRAGIAGGADSSSVLPIGVSKKLARVLVDVNKARTMSQRLKLFSRLRLRDLMPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQSWSEGKLKEEVMTAFIPPYKQLLAEDNNICGNSSLADYAKLRPAFDRKHGTVTAANSTPLTDGAAAVILMTESRTKELGLVPLGYLRSYAFTAIDVWQDMLLGPAWSTPLALERAGLTMADLTLIDMHEAFAAQTLANIQLLGSERFACNVLGRAHATGEVDDSKFNVLGGSIAYGHPFAATGARIITQTLHELRRRGGGFGLVTACAAGGLGAAMVLEAE", "output": "Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed."}]}
+{"id": "function_test_2034", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKPTTIASLQKCKQEKKRFATITAYDYSFAKLFADEGLNVILVGDSLGMTVQGHDSTLPVTVADIAYHTTAVRRGAPNGLLLADLPFMAYATPEQAFENAATVMRAGANMVKIEGGEWLVETVKMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEASDRLLSDALALEAAGAQLLVLECVPVELAKRITEALVIPVIGIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLAETGDIRAAVRQYKAEVESGVYPGEEHSFH", "output": "Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate."}]}
+{"id": "function_test_2035", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MYKNWRELIKPKRLQVDADSLSDTYGKFMAEPFERGFGTTLGNSLRRVLLSSLQGAAITSVRIKGVLHEFSNIPGVTEDVTDIILNLKGVLLKLHGSDSRNIRIVKKGAGVITAADIITDSHVDVLNPDHHILTCGKDADIELDMVVAMGKGYVPAERNRDDKAPVGTIPIDSLFSPVKKVNFTVTNARVGQITDYDKLILEVLTDGSVRPDDGVAYAAKILKEQLQIFINFDEETETVVEEESEESRKINENLYRSVEELELSVRSANCLKNANIHLIGDLVQRSEAEMLKTQNFGRKSLNEIKDILAEMGLSLGMMLENFPDPEYLKMIQEGKEDL", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_2036", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MESKLPLLVGVTGGLGSGKSMVCRYLASMGCALFEADVVAKELQVRDSKVIEGITALFGKEVYSYNPKGELQLNRKDIAQVVFSNQEKLGALNRLIHPRVAVAFQQACDNAARSNVAILVKEAAILFESGAHAGLDVVVVVQAATELRVERAVQKGLGTREEILRRLAVQWAPEKLAALADVVIDNNGTPEALYEKTKQLYEQLLQQAMLRR", "output": "Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A."}]}
+{"id": "function_test_2037", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSVIVKVIGREIMDSRGNPTVEADVHLADGSWGRAAAPSGASTGTREALELRDGDKSRYLGKGVLKAVGFINNEIATALAGQNALEQSTVDQVMLDLDGTENKEKLGANAILAVSLATAKAAAQSKKVELYEHIADLNGTPGVYSMPLPMMNIINGGEHADNSVDIQEFMIQPIGAKNFREALRMGAEIFHSLAKVLKADGHSTAVGDEGGFAPNLASNEAALAAIKVAVANAGYELGKDITLALDCAASEFYDKEANIYNLKGEGKKFTSEEFNFFLQDLTQQYPIVSIEDGLDESDWDGFAHQTKLMGDKIQLVGDDLFVTNTKILKRGIDNGIANSILIKFNQIGSLTETLAAIKMAKDAGFTVVISHRSGETEDSTIADLAVGTAAGQIKTGSLSRSDRVAKYNQLLRIEEQLGDKAPYNGLKEVKGQ", "output": "Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis."}]}
+{"id": "function_test_2038", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAIKLAINGFGRIGRNIVRALYESGLSNEIKIVAINELADPEAIAHLLKYDTSHGRFFFPVKLGEDTISVAGDAIALFCEPNPAELPWKTLGVDVVLECTGVYHSREHAQLHLTAGAKKVLFSHPADNDVDATIVYGINDDELKPEHTIVSNGSCTTNCVVPVIKVLDDAFGIESGAITTIHASMNDQPVIDAYHHDLRRTRAASQSIIPVDTKLARGIDRILPKFKGRFEAIAVRVPTINVTAMDLSVTVNTDVDLNAVNNALKAQAKDRLEGILSYTAEPLVSIDFNHDPHSCIIDGTQTRVSHKRLIKLLVWCDNEWGFANRMLDTARAMVALEKITNIK", "output": "Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate."}]}
+{"id": "function_test_2039", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPMTGFYETISPRDQQRPPIWFLRQVGRYIPQYQELKRNRSLKDFFLDTESIVEATLLGPSLLGVDAAIVFADILSILEGFSVDYRFAPGPEVSYSPHEPLIFTKDPQETFSFLLEAIQQLTKRLTVPLIAFAASPFTLASYLIEGGASRDYPKTIAFLYQYPDRFKALLDEITLGTATYLQMQVQAGAAAIQLFESSSLRLPPHLFAKYVVAPNTKLIRQIKQTGNPPISLFCRCFYQEFLSLYAIGADTLHPDYHVELPEVYRQIHSPGSIQGNFDPALLLLPQDALIAHLEAYLAPLKQQSHYIFNLGHGILPQTPIENVQAVVSCLTSISTS", "output": "Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III."}]}
+{"id": "function_test_2040", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSDNPADLPVLVAGGGIGGLAAALALVRRGFSVKVLEQAPEIGEIGAGIQLGPNAFHAFDALGIGEKARGRAVYTDEMVMHDAIDGSLVGRIPTGEAFRQRFGNPYAVIHRVDVHLSLLEGAQETGKVEFLTSTRALRIEQDEGSVTVYDQHGNAHKGIALIGADGVKSVVREQFVGDAARVTGHVVYRAVVDKKDFPESLQWNAASIWVGPNCHLVHYPLRGGEQYNVVVTFHSRQPEQWGVTEGSKEEVQSYFQGICPQARQLIDLPKTWKRWATADREPIGQWSFGRVTLLGDAAHPTTQYMAQGACMAMEDGVTLGEALRVNNNDFPKAFELYQRSRVARTARIVLSSREMGRIYHAQGVERLVRNDLWKGRTPERFYDAMEWLYGWNVGNCLAKD", "output": "Catalyzes the NAD- or NADP-dependent conversion of 3-hydroxybenzoate to gentisate. The affinity of the enzyme toward NAD is twice as high as for NADP."}]}
+{"id": "function_test_2041", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSSSQSLRLGVNVDHVATIRNARGGDRPDVVRIALAAIAAGADGITAHLREDRRHIRDSDMARLKAEIEKPLNFEMAATAEMQGIALATQPHAVCLVPERREELTTEGGLDAAGQYNALAPFIAKLNDAGIRVSLFIAADPRQIEAAAKLRAPVIEIHTGGWCDAVVEGDSGKADAEWRRIVEGAALARSVGLEVHAGHGLDYATAETIAALPEITELNIGYFMMGEALLVGIAETVRTMRAAMDRGRATLKTRTA", "output": "Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate."}]}
+{"id": "function_test_2042", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDRPAYRRVVVKLSGEYLAGSQPFGIDQPTIDRIAGDLAEARALGVEIAVVVGGGNIFRGVEVSSRGVSRPTGDTMGMLATVMNCLALEAALERRGQSARALSSFVMPEVCELFTRRAAHKYLAEDRIVLLAGGTGNPYFTTDTTAVLRAAEIGAQAVLKATNVDGVYSSDPKKDPSAKRFERLSHSQALEGGYKVMDATAFALARETALPIIVFSIAEPGSIGAILKGTGRGTIVAS", "output": "Catalyzes the reversible phosphorylation of UMP to UDP."}]}
+{"id": "function_test_2043", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGAHNYAIYLDKARNLLFATVEIESEERWNAVASTDVCQRWWKYMTDVMPANPDNSPVSSELQEVFYLP", "output": "Involved in the anomeric conversion of L-rhamnose."}]}
+{"id": "function_test_2044", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGTNEWHVERRDSIGTESPVAREVLETGTLSIVVLGASGDLAKKKTFPALFHLYKQELLPPDEVHIFGYARSKISDDELRNKLRSYLVPEKGASPKQLDDVSKFLQLVKYVSGPYDSEDGFRLLDKEISEHEYLKNSKEGSSRRLFYLALPPSVYPSVCKMIKTCCMNKSDLGGWTRVVVEKPFGRDLESAEELSTQIGELFEEPQIYRIDHYLGKELVQNMLVLRFANRFFLPLWNHNHIDNVQIVFREDFGTDGRGGYFDQYGIIRDIIPNHLLQVLCLIAMEKPVSLKPEHIRDEKVKVLESVLPIRDDEVVLGQYEGYTDDPTVPDDSNTPTFATTILRIHNERWEGVPFIVKAGKALNSRKAEIRVQFKDVPGDIFRSKKQGRNEFVIRLQPSEAIYMKLTVKQPGLEMSAVQSELDLSYGQRYQGITIPEAYERLILDTIRGDQQHFVRRDELKASWQIFTPLLHKIDRGELKPVPYNPGSRGPAEADELLEKAGYVQTPGYIWIPPTL", "output": "Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis (By similarity)."}]}
+{"id": "function_test_2045", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MASSVLSSAAVATVSRTPAQASMVAPFTGLKSTVGFPATKKNDDITSLASNGGRVQCMKVWPTQNMKRYETLSYLPPLTTDQLARQVDYLLNNKWVPCLEFETDHGFVYREHHNSPGYYDGRYWTMWKLPMFGCTDPAQVLNELEECKKEYPNAFIRIIGFDSNRQVQCVSFIAYKPAGY", "output": "RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site. Although the small subunit is not catalytic it is essential for maximal activity."}]}
+{"id": "function_test_2046", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEINNQNQCIPYNCLSNPEEVLLDGERILPDIDPLEVSMSLLQFLLNNFVPGGGFISGLFDKIWGALRPSDWELFLAQIEQLIDQRIEATVRAKAIAELEGLGRSFQLYVEAFKEWEETPDNTAARSRVTERFRIIDAQIEANIPSFRIPGFEVPLLSVYAQAANLHLALLRDSVIFGERWGLTTTNVNDIYNRQVKRIHEYSDHCVDTYKTELERLGFTSRAQWKIYNQFRRELTLTVLDIVAVFPNYDGKLYPIQTKSELTREIYTSPVSEYYYGAINNYNQNGIQTERQIRQPHLMDFFNTMTMYTSYNRREYYWSGLEMTAYFTGFAGPQVSFPLAGTRGDAAPPFNVRSVNDGIYRILSAPFYSAPFLGTSVLGSRGEEFMFALNNISPPPSARYRNPGTVDSLVSIPPQDNSVPPHRGSSHRLSHVTMRNSSPIFHWTHRSATTTNRINSDVITQIPMVKAYNLHAGATVVRGPGFTGGDILRRTSNGMVVTLRVDASAVRNQRYRIRFRYAATSNFYFVVRRGNLGVNGREIMKTMSTGEELKSASFVLGEFITPFNFFENQVPLQIEIQSLSPGGEVYLDKIEFIPADTTFEAEYDLERAQKAVNALFTSTNQRGLKTDVTDYHIDQVSNLVECLSDEFCLDEKRELSEKVKHAKRLSDERNLLQDPNFTSINGQLDRGWRGSTDITIQGGNDVFKENYVTLPGTFDECYPTYLYQKIDESKLKAYTRYELRGYIEDSQDLEVYLIRYNAKHETLNVPGTDSLRTLSVESQNGRCGELNRCMPHIKWNPDVDCSCRDGEKCAHHSHHFSLDIDVGCTDLQEDLGVWVVFKIKTQEGYARLGNLEFIEEKPLVGEALSRVKRAEKKWRDKREKLELETKRVYTEAKEAVDALFVDSQYDRLQADTNIGMIHAADKLVHRICETYLPELPFIPGINAIIFEELENRISTAFFLYEARNVINNGDFNNGLTCWNVKGHVDVQQSHHRSVLVIPEWEAEVSQKVRVCPGRGYILRVTAYKEGYGEGCVTIHEIEDNTDELKFRNCEEEGDYSNDTGTCNDYPASQGAAGCADVCNSRNVGYKDAYETNTSASVNYKPTYEEETYTDVREDNHCEYDRGYVNYPPLPAGYVTKELEYFPETDTVWIEIGETEGKFIVDSVELLLMEE", "output": "Promotes colloidosmotic lysis by binding to the midgut epithelial cells of many lepidopteran larvae. Toxic to Plutella xylostella."}]}
+{"id": "function_test_2047", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDTATKTGYADVLVGLQYGDEGKARVVDHLAAGYDVIARFNGGANAGHTIATSEGILRLRQVPSGVLHPRVSLYIGSGCVIGLRQLASEIEMLAGQGIDLAGRLTISDRCPVVQPAHFLSDRRDGGRIGTTGNGIGPCYADLAARMRGGERSAFQLCDLMRDESRVFEQMMRLAAQRDDEDIAVLIQEMRQAWQVVRPFVTDNPVALLERVEGGARVLFEGAQSVMLDVVQGAQPWVTSSHTLPSYAYVGGDLPCRYHRKTIGVAKAMVSRVGSGPLPTELGAERSEAYCADAGREGRGRADEAARFDPRALLAQGDAFSTGIAIRMLSNEYGTGTGRPRRVGLLDVAQLQLAIRQFGVDEVYLNKCDSLAVFAQTRDRCIPVVVGSRDGNAMHVMRFPAFDESVIPRDDATPLPPQLETLLEWLADVLGRPLRGIGLGPQRAQMRLFKTQP", "output": "Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP."}]}
+{"id": "function_test_2048", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSTLVLLRHGESVWNAEGLFTGWVDVDLSPKGEEEARRGGRLLAEAGIRPDVVHTSLLKRAIRTANIALEEAGLHWIPVKRSWRLNERHYGALQGKNKAQTRAEFGDEQFMIWRRSYDTPPPPLAEDSEFSQHNDPRYATLPPELMPRTECLADVVRRMLPYWYDAIIPDLAAGRTVLVAAHGNSLRALVKHLDNIDDKSIAGLNIPTGIPLVYELNDDFTPRKTGGEYLDPEAAKEAIEAVKNQGK", "output": "Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate."}]}
+{"id": "function_test_2049", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLRTMLNGKIHRATVTHADLHYVGSITIDADLMDAANLVDGEQVHVVNITNGHRLVTYVLTGERGSGVIGINGAAARLVAPGDLVIIISYVQLTEAERATHRPHVVHVDANNRIVALGDDLAEPVPGSDQKSGALLP", "output": "Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine."}]}
+{"id": "function_test_2050", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAKHERGLRFQPAGGVKTVQIPAGKKQRLTIERLSDDGRGIAFLEGKTWFVAGSLAGEEVEARVLNARGKVVEARTERVFTASTMRRAPACEYFGRCGGCSVQHVPHEEQLALKQRMLAEQLLRVANVVPDEWAAPLSGAELAYRRRARVAVRWDAKAKRLDVGFRAAASQDIVSIEHCPVLVQALQPIMNELPGMLKNFSKPQALGHVELFSGVATAVLLRHTAPLAEADLALLQAFCSKHGAQLWLHGEGEPQPVSPGDTLGYRLEPWNLQLAWRPGDFIQVNAAVNTAMIEQALQWLAPAKDERVMDLFCGLGNFALPLAGLAREVVAVEGVATMVERAAVNAMSNDLHNVQFFQADLSQPLTHADWAAEGFSTVLLDPPRDGAFEVVRQIRKTGARRLLYVSCNPATLARDTVELISQGYRLKRAGILDMFPQTAHVEAMALFEMSK", "output": "Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA."}]}
+{"id": "function_test_2051", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MASPIEVRLHMTYPDFTVRTDLTLPGSGITALFGPSGSGKTTCLRCIAGLEKAGQGFIRVHDEVWQDTEKGVFLAPHKRAIGYVFQEASLFPHLSVRANLEFGMKRIPRQQRNIQLPQATELLGIDHLLERSPDKLSGGERQRVGIARALLTSPRLMLLDEPLAALDARRKSEILPYLERLHRELDIPMLYVSHAQDEVARLADHLVLLEAGNVLASGPIRETLARLDLPLAMGGDAGVVIEGTVSAYDRNYQLLSVTLPDSTLCMRVAHAEMQIGTLLRVKVQARDVSLNLQPDDQSSILNRLPVTVMEEALADNSAHVLVKLDAGGTPLLARITRYSSDQLNLHRGQSLWAQIKAVAVLA", "output": "Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system."}]}
+{"id": "function_test_2052", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MITSIFGKVTFVGKRKIIVEHNWISYWFNTKENHKFEKNLEKNKQIFCHIIKKIVANQIIEEAFAFNTLEEKEWFCRLIELNGIGSKTALNLLNNDLEEIKQYILENNYSALCGINGVNNKIARALLSLEIFEKSENNKNIKGVQVADGYDELFETLKSLGYKQQEIQDALKMIEVKPDFDISQLVAEVIKLMSFKNNEITNKTA", "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."}]}
+{"id": "function_test_2053", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSVPNSPEAPWAVGQLNDQVKNWIQRLGFIWVEGQVTQVNMKSTWRFSYITLRDVNLEASVSLTVETSALKNLATPVKDGDRIVVHGKPSFYSKRGSFSLWVTEIRQVGIGQLLAQIEQLKKAMFAEGLFDPRLKTPLPFLPTTVGLITGRGSAAERDVMEVAKRRWPAVRFRVINTAVQGPKTVPQVVDALQELERDSAVDVIIVARGGGSVEDLLPFSEETLVREVSRLRTPVVSAIGHEPDNPLLDYVADVRAATPTDAAKTVVPDVVQELRIISEARQRGAGALRNWVAHERKGLAQIRTRPVMADPSLPVARQQDIIAEALQRKDRALGVHVRSLRSSIESLKAQVNALGPSQTLARGYSIVQVIPRDKSGAQVVTTVDQVTPGSQLRIRVPDGSITAAAMGVQAAPGGVMNKNSNTTDSTDNTENGTGEA", "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."}]}
+{"id": "function_test_2054", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYDWFLKEGLLEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEESKNRDATYAAPLRVKVRLIIKETGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDATIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSNDQEIIDLLGDSEYLRNTLEKDGTENTEQALLEIYERLRPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKANKKLHLKHRLFNQRLAEPIVNSETGEIVAEEGTVLDRRKLDEIMEVLETNANSEVFELEGTVIDEPVEIQSIKVYVPNDEEGRTTTVIGNALPDSEVKCITPADIIASMSYFFNLLNGIGYTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTDSITPQQLINIRPVIASIKEFFGSSQLSQFMDQANPLAELTHKRRLSALGPGGLTRERAQMEVRDVHYSHYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTNSITDQIDYLTADEEDSYVVAQANSRLDENGRFLDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATACIPFLENDDSNRALMGANMQRQAVPLMNTEAPFVGTGMEHVAARDSGAAITAKYRGRVEHVESKEILVRRLVEENGTEHEGELDRYPLAKFKRSNTGTCYNQRPIVSVGDVVEYNEILADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEARDTKLGPEEITRDIPNVSENALKNLDDRGIVYVGAEVKDGDILVGKVTPKGVTELTAEERLLHAIFGEKAREVRDTSLRVPHGAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIVQKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPLGVPSRMNIGQVLELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRISVGVMYMLKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEILTYKSDDTVGRVKTYEAIVKGENISRPSVPESFRVLMKELQSLGLDVKVMDEQDNEIEMADVDDEDATERKVDLQQKDVPETQKETTD", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_2055", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSSGSRSFFTPQETRLELPQGAAHQTPDITRPASPSENDRAPFLNGGPSDAREDVRMGAKALRNDSEKPAVGIMALAPILCYCAASITMTVVNKFTVSGRGFNMNLLVLLIQSTVGVTCVWIAERAGLIQLRGLNAKDAWNWMPLSIMLVFVIWTGSKALQYLNISVYTIFKNLTIILIAYGEVMWFGGRVTRIVLCSFLFMVLSSVIAAWSDISNVFAIGNLSMPHTPDSIMGGMAKDPITGALFPAFDPLKTEKDAINAQLQSASANDVIEGFQGYGLLSSGYVWMALNCICSATYVLLMRKRIKVTGFKDWDTMFYNNFLSIPVLLLMSFLVEDWSYANLHKNFPDDKQTKLISAIVFSGACAILISYTTAWCIRATSSTTYSMVGALNKLPVALSGMVFFHDPPVTFSSVSAIAVGFFAGLVYAFGKNKQAEAAKLGGHASANGSSSMSGSKDGSSLPMHTFNDRKD", "output": "Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen."}]}
+{"id": "function_test_2056", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPVDKNLRDLEPGIHTDLEGRLTYGGYLRLDQLLSAQQPLSEPAHHDEMLFIIQHQTSELWLKLLAHELRAAIVHLQRDEVWQCRKVLARSKQVLRQLTEQWSVLETLTPSEYMGFRDVLGPSSGFQSLQYRYIEFLLGNKNPQMLQVFAYDPAGQARLREVLEAPSLYEEFLRYLARFGHAIPQQYQARDWTAAHVADDTLRPVFERIYENTDRYWREYSLCEDLVDVETQFQLWRFRHMRTVMRVIGFKRGTGGSSGVGFLQQALALTFFPELFDVRTSVGVDNRPPQGSADAGKR", "output": "Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety."}]}
+{"id": "function_test_2057", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEDSTSPKVTLYTYFRSSCSARLRIALNLKSIPYTPIAVNLLKGEQSSPENIALNPSGTVPTLIVEHDSKEPVTITQSLAALEYLEEITPASSHALLPPASNPEARAVVRTLVDIMSCDVQPVTNLRILKRVAPFGVDRAAWSKDLIEDGFRAYEAIAAKSAGLFSVGDSITMADVCLLPAVWGAERAGVKVEKFPTIYRVAQRLEEEDAVKRAHWRTQPDTPEEFRVSSS", "output": "Maleylacetoacetate isomerase; part of the L-tyrosine degradation gene cluster that mediates the biosynthesis of the brownish pigment pyomelanin as an alternative melanin . The 4-hydroxyphenylpyruvate dioxygenase hppD catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisic acid (HGA) . The protein hmgX is crucial for this conversion and thus, probably functions as an accessory factor to mediate specific activity of hppD . The homogentisate 1,2-dioxygenase hmgA is then involved in the cleavage of the aromatic ring of HGA and its conversion to 4-maleylacetoacetate . When hmgA activity is lowered by the cell wall integrity (CWI) signaling pathway, HGA accumulates and leads to the production of pyomelanin through benzoquinone acetic acid after oxidation and polymerization . On the opposite, in non-stress conditions, both hppD and hmgA activities are balanced and HGA is degraded into 4-maleylacetoacetate . 4-maleylacetoacetate is further converted to 4-fumarylacetoacetate by the maleylacetoacetate isomerase maiA, which is degraded into fumarate and acetoacetate by the fumarylacetoacetase fahA (Probable)."}]}
+{"id": "function_test_2058", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MATQPPQDQTSTTPSLPPHLDPTTYPRILTSATHNIHLELTYSTLNPTVALEHTSSPAAGANVLFLGTTRDTFEGRAVSQLSYTSYPPLALKSLMSIATRAVEKFDLKGVYIAHRLGVVPISEASIVVAVSAGHRGMAWKAAEEVLEEVKEKVEIWKREEFVDGGMEWRENRERDAEGRILSSTEGGK", "output": "Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group."}]}
+{"id": "function_test_2059", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTTSESSATSSVKIYFRLLSYVRPYVGIFLLSIIGFVIFASTQPMLAGILKYFVDGLTNPEAVLFPNVPYLRELQLLQAVPLLIVLIAAWQGLGSFLGNYFLAKVSLGLVHDLRVELFNKLLVLPNRYFDTTNSGHLISRITFNVTMVTGAATDAIKVVIREGLTVVFLFIYLLMMNWKLTLVMLAILPLIAVMVGTASKKFRKQSKKIQVAMGDVTHVASETIQGYRVVRSFGGEAYEQARFAQASNSNTQKQLRMTKTGAIYTPMLQLVIYSAMAVLMFLVLFLRGEATAGDLVAYITAAGLLPKPIRQLSEVSSTIQKGVAGAESIFEQLDVEEEVDTGTIERERVTGHLEVKNLSFFYPQTARQVLNDISFSAAPGQMIALVGRSGSGKSTLANLIPRFYGHDIGNILLDGVEINDYRLRNLRRHIAQVNQNVTLFNDTIANNIAYGDLAGAPRADIEAAAADAYAREFIDQLPQGFDTQVGENGVLLSGGQRQRLAIARALLKNAPLLILDEATSALDTESERHIQAALDHVMKGRTTLVIAHRLSTIEKADLILVMDAGQIVERGTHTELLAQNGYYARLHAMGLDEPAPVGAV", "output": "Involved in lipopolysaccharide (LPS) biosynthesis. Translocates lipid A-core from the inner to the outer leaflet of the inner membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation."}]}
+{"id": "function_test_2060", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDKPYHVKFYSYNFPLPKPVVTAHGHWQRRRGLIVELTDQRGNRGRGEIAPLPWFGTEDLASATDFCRSLKGRITPAQIEKIGDRLPCCGFAFGSAEWELESGSVIENSPNSLSYCQLLPTGEAALDYLASNPQLGASTFKWKIGVGDFAVERDLYGQLWRRLPEGCQIRLDANGGLSVDIAQQWLTLLDRQRENSGPKIQYLEQPLPPGEIDEMFRLQEDFATSIALDEAVCSLAQLAQLYDKGWSGLYILKAAIMGNPRVLNHWLKTHPIPAIFSSVFETAIARGQVLALAQKWNLPDHAVGFAPLREPITEATPDSV", "output": "Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB)."}]}
+{"id": "function_test_2061", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAKIKKKGTSGQAKNYITRTQAVRKLQISLPDFRRLCIFKGIYPREPRNKKKASKSATQSTTFYYTKDIQYLLHEPLLRKFREQKALAKKIARSLGRGEVSDAARLEKNHAPKLTLDHVIKERYPTFIDALRDLDDALSLLFLFANLPSTSHVPPKTIALCQRVTHEFQHYLITTNSLRKSFLSIKGIYYQATIQGQDIMWLVPYRFVQRVNGDVDYRIMATFVEFYTTLLGFVNYRLYSSIGLRYPPKFDTRLDENGAELAAFTLEGRTVGDAPKAIEPAKSSSDAANQEVSAEVQKKVDNVIKKAGLDQASSEQPTETAEEVTDAIDKFETTAPEADTLPQPDMSGDQAGSLFAPFTFYISREAPKTPLEFILRAFGCKRIGWDTVLGGGAFTHNEADPRITHQIVDRPSLPESSLPSIPAAATDGGAVQKVKPGTRVPGRTYVQPQWVWDCINEGKLLRPDLYAPGATLPPHLSPWVNPKKGGYDPRASLAEQEEDGEADIDAEEESDEEMEEAGEEKPAPTAANESEDSEDESVDGGMDVAETDDDDSESEEEEEEEDEFAGIDDEDAGSESEDEEETARTQHQKELEAEAAGLPFSSSGAGDDAAAKKKSQAKKRAAKKRQEEEELERQKMMMSRKKRKLLEKMMYSNKKTAEESAKLRSKRRKIEKGAAGK", "output": "Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome."}]}
+{"id": "function_test_2062", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLYLVGLGLADERDITVRGLEVVKKAERVYLEAYTAILLVDKAKLEAFYGRPVIEADRELVETGSDDILANADKVDVAFLVVGDPFGATTHTDLVLRARELGIESKVIPNASIMSGIGCTGLQLYNFGQTVSMVFFTETWKPSSYYDRVKENVQIGLHTLVLLDIKVKEQSLENMARGRLIYEPPRFMTVAQCAAQMLETEEERQEGVWGPDSLAVGAARVGAEDQKLVAGTLQELTQVDMGRPLHSLVLLGRRAHDLEKDYIRRFAVDEATFDAAWQNGKYGSS", "output": "S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis."}]}
+{"id": "function_test_2063", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTGSSDFPVKGLRGRLTPNAPLGPRAWFRVGGPADWLFVPEDQDDLALFLREKPATMPVTVLGACSNVIIRDGGIAGTVIRLARGFADITVQGNSLIVGAAALDITVAEHAAAAGLAGLEFLAGIPGSIGGAVRMNAGAYGSDINAVFEWADILTAEGELRRLSHDELGFAYRHSELPEGSVVIRASLRGTPDNADAIRSRIADIRASREASQPVRARTGGSTFRNPDGHKAWQLIDEAGCRGLQIGDAQVSEKHCNFLLNLGQASSADLETLGETVREKVLAQSGVDLHWEIKRIGRKSEGEQTV", "output": "Cell wall formation."}]}
+{"id": "function_test_2064", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTNVVVSGEQLQEAFREVAVMVDSTVAITAGPRGKTVGINKPYGAPEITKDGYKVMKGIKPEKPLHAAITSIFAQSCFQCNDKVGDGTTTCSILTSNMIMEALKSIAAGNDRVSIKNGMQKAKDAVLEGITSMSRTIPLEKMDEVAQVAIISANGDKDIGNSIADAVKKVGKEGVITVEESKGSKELEVELTTGMQFDRGYLSPYFITSNEKMIVEFDDPYLLITEKKLSIIQPLLPILEAVVKSGKPLLIIAEDIEGEALSTLVINKLRGGLKVTAVKAPGFGDRRKEMLEDIAALTGAKYVIKDELGIKMEDLTLEDLGTAKNVKVTKDNTTIVSGSSDSDRVKARVEQIKSQIETSTSDYDKEKLRERLAKLSGGVAVLKVGGVTEVEVKERRDRVEDALHATRAAIEEGIVPGGGVALLYASSALDKLKGGSDEEQIGINIIKKVLSAPIKRLVKNAGLESAVIIDHLTKQNDKELIYNVEAMNYANAFTAGVIDPAKVVRIAFETAISVASVLITTESMIVDVPNKEENASSSMGAGGMGGMNGF", "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."}]}
+{"id": "function_test_2065", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRMIDIIEKKRDGHTLTTEEINFFIGGYVKGDIPDYQASSLAMAIYFQDMNDDERAALTMAMVNSGDMIDLSDIKGVKVDKHSTGGVGDTTTLVLAPLVAAVDVPVAKMSGRGLGHTGGTIDKLEAIDGFHVEIDEATFVKLVNENKVAVVGQSGNLTPADKKLYALRDVTGTVNSIPLIASSIMSKKIAAGADAIVLDVKTGSGAFMKTLEDAEALAHAMVRIGNNVGRNTMAIISDMNQPLGRAIGNALELQEAIDTLKGQGPKDLTELVLTLGSQMVVLANKAETLEEARALLIEAINSGAALEKFKTFIKNQGGDETVIDHPERLPQAQYQIEYKAKKSGYVTELVSNDIGVASMMLGAGRLTKEDDIDLAVGIVLNKKIGDKVEEGESLLTIHSNRQDVDDVVKKLDSSITIADHVVSPTLIHKIITE", "output": "Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate."}]}
+{"id": "function_test_2066", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQREEKQLEACLDALISQVSDIKNSLVGFIHKLENEFDRLTWPSVLDSFALLSGQLNTLNKVLKNEKTPLLRNQVIIPLLLSPDRDEEIMRLTEGRVPVFSHEVVPDHLRTKPDPDVEELEKQLSAEAARITTEAAQKQVQSMNKMCSNLLDKISKEERESELGSLRQNKQTFNPTDTNALVAAVAFGKGLSNRRPPGQGGPMAPGQTGASGMLPSAAGMQQVPMSLQSNQQQQHMAGVSMSQGNQPGKMPSSIKTNIKSASMHPYQR", "output": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins (By similarity)."}]}
+{"id": "function_test_2067", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKGPEKAYLVSDKATKMYSLTMDSSEKNNCGKPPLQDDENPHIKYHCHNNNTKAYDARQREQTSAKKKLCIASLICFVFISAEIVGGYIAGSLAVVTDAAHLLVDLSSFFISLGSLWLSSKSSTMRLTFGWYRAEILGALMSIITIWLVTGVLVYLAIERIIRPDYTIDGTVMLITSACALGANVVLALILHQSGHGHSHAGGKHEHMASEYKPQTNASIRAAFIHVIGDLFQSISVLISALIIYFKPEYKIADPICTFIFSIFVLITTVTVLRDLLNILMEGTPRGIHYSDVKQSILAVDGVKSVHSLHLWALTMNQVILSAHIATDILGESKRILKDVTQNVCSSFPFHSVTIQVEPVEEQSPECMFCYEPTQ", "output": "Proton-coupled zinc ion antiporter mediating the entry of zinc into the lumen of pancreatic beta cell secretory granules, thereby regulating insulin secretion."}]}
+{"id": "function_test_2068", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNREERLKRQERIRNFSIIAHIDHGKSTLADRILEKTGALSERELREQTLDTMELERERGITIKLNAVQLTYKAKNGEEYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLAIDNNLEILPVINKIDLPSAEPERVRQEIEDVIGLDASDAVLASAKVGIGIEEILEKIVEKIPAPSGDPDAPLKALIFDSLYDPYRGVVAYVRVVDGTVKPGQRIKMMSTGKEFEVTEVGVFTPKQKVVDELTVGDVGYLTASIKNVKDTRVGDTITDAERPAAEPLPGYRKLNPMVFCGMYPIDTARYNDLREALEKLQLNDAALHFEPETSQALGFGFRCGFLGLLHMEIIQERLEREFHIDLITTAPSVVYKVHLTDGTEVDVDNPTNMPDPQKIDRIEEPYVKATIMVPNDYVGPVMELCQGKRGTFVDMQYLDEKRVMLIYDIPLSEIVYDFFDALKSNTKGYASFDYELIGYRPSNLVKMDILLNGEKIDALSFIVHRDSAYERGKAIVEKLKDLIPRQQFEVPVQAAIGNKVIARSTIKALRKNVLAKCYGGDVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKIDDQKK", "output": "Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner."}]}
+{"id": "function_test_2069", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MHQSKEERVHRVFEKISAHYDRMNSVISFRRHLKWREDVMRRMNVQKGKRALDVCCGTADWAIALAEAVGPEGEVYGLDFSENMLKVGEQKVKARGLGNVKLIHGNAMQLPFPDNSFDYVTIGFGLRNVPDYMTVLKEMHRVTKPGGMTVCLETSQPTLFGFRQLYYFYFRFIMPLFGKLLAKSYEEYSWLQESAREFPGRDELAEMFREAGFVDVEVKPYTFGVAAMHLGYKR", "output": "Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)."}]}
+{"id": "function_test_2070", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSHNPVRPWRNVYRRKSRQIMVGNVPVGGDAPISVQTMTNTLTTDVAATVAQVQAAAEAGADIVRVSVPDEASARALREIVRESPVPIVADIHFHYRRGIEAAEAGAACLRINPGNIGSPDRVREVIRAARDHGCSIRIGVNAGSLEKHLLEKYGEPCPEAMVESGLEHIRILQDNDFHEYKISVKASDVFLSAAAYQGIAEATDAPIHLGITEAGGLVSGTIKSAIGLGNLLWMGIGDTIRVSLSADPVEEVKVGYEILKSLGLRHRGVNIISCPSCARQGFDVIKTVEALEKRLEHIKTPMSLSIIGCVVNGPGEALMTDVGFTGGGAGSGMVYLAGKASHKMSNERMIDHIVEEVEKKAAALDAASAAEAAE", "output": "Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate."}]}
+{"id": "function_test_2071", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MESRLKPGLIVLCGPTAAGKSSLAIAIAQRLGSPILSADSRLVYRDFNIGTAKPTPAEQQQVPHYLMDLCDPRQVFTVGDYQDCAVPLIQQLQEKGMLPLLVGGTGLYIKAIVNGLRFPRIAPQPKLRSQLQALGQPLCHALLQRVDPVAGDRIHVNDRVRTLRALEVFYVSGDRLTDLQQEQPPSYPILQIGLDSDRLEARIQQRTQQMLTSGFVEEVQGLCDRYGSDLPLLNTLGYRQVCAFLQGSLSRSELPEQIVLQTRQYAKQQRTWFRADSSIQWIDAEAGNRLERALDLIERFRKSEGV", "output": "Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)."}]}
+{"id": "function_test_2072", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MCGIIGIIGREDLSERLFQGLRRLEYRGYDSAGMCTIHDGKLDRRRAEGKLDNLGRVLANDPLPGKIGIAHTRWATHGAPTVANAHPHIAGDVAVVHNGIIENFKTLRDELLERGHHFESETDTEVVAHLLDEQMQAGKDPRHAVSKVLKKLRGAFALAILFKNYPDLLIGARLGSPLVVGYGDGENYLGSDALALAPLTQKISYLEEGDWVVLTREGIEVHDIEDRIVERPVVLSGASGLMVEKGNYRHFMQKEIFEQPVVVAQTLQSYLRPVEGQVALPDPDFDLSQIKRVTIVACGTSYYAGMVARYWIERFARVPVEIEAASEYRYREPVMEEGGLSLFISQSGETADTLAALRHARAGGQKIAVVVNVPTSSMAREADLLLPTHAGPEIGVASTKAFTCQLAVLAALATHIARVKGQLTQQEEQDIVRHLAEAPAALNAALAFNDTIENVATAIAPARDVLYIGRGPDYPLAMEGALKLKEISYIHAEGYAAGEMKHGPIALIDDKVPIIVLAPSGPLFEKTVSNMQEMQARGGKVILISDEKGIQEAGDNCLATLTMPKVHPLIAPIVYAIPVQLLAYHVAVIKGTDVDQPRNLAKSVTVE", "output": "Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source."}]}
+{"id": "function_test_2073", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTAPAAAIRRLDAREPEFLATLDALLAFEGGADARIDAAVSEILRAVRTTGDAAVLEYTRRFDHLDVKSMVQLELSKSELKAALDSLTVEQREALRVAADRVRVYHERQRAESWDYVEADGTRLGQKVTPLDRVGLYVPGGRASYPSSVLMNAIPAKVAGVGELIMVVPTPNGEKNPLVLAAAAITGVDRVFTIGGAQAVAALAYGTQTLPQVDKIVGPGNAYVAEAKRRVFGTVGIDMVAGPSEVLIISDGSGQAGWVAMDLFAQAEHDELAQSILLCTDAGFIDAVAASIERLLPSMPRRETIAASLANRGALIHVDSLEQACAIANRIAPEHLELSLDDAEPWIGRIRHAGAIFVGHWSVEALGDYCAGPNHVLPTMRSARFSSPLGVYDFQKRTSIVQISEAGAQTLGRVASILARGEGLQAHARSAEMRLHDR", "output": "Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine."}]}
+{"id": "function_test_2074", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSQTITLIKDKILSDNYFTLRNITYDLTRRNGEVIRHKREVYDRGNGATILLYNSTKKTVLLVRQFRVATWVNGNQDGMLIETCAGLLDNDEPEVCIRKEAIEETGYDVGEVRKIFELYMSPGGVTELIHFFIAEYHDSERASIGGGVEDEEIEVLELPFSRALEMVRSGEIRDGKTVLLLNYLQTSHLMD", "output": "Nucleoside diphosphate sugar hydrolase that hydrolyzes GDP-mannose as its preferred substrate, yielding GMP and mannose-1-phosphate."}]}
+{"id": "function_test_2075", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MALRAMRGIVNGAAPELPVPTGGPTVGAREQALAVSRNYLSQPRLTYKTVSGVNGPLVILDHVKFPRYAEIVHLTLPDGTKRSGQVLEVSGSKAVVQVFEGTSGIDAKKTSCEFTGDILRTPVSEDMLGRVFNGSGKPIDRGPVVLAEDFLDIMGQPINPQCRIYPEEMIQTGISAIDGMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKKSKDVVDYSEENFAIVFAAMGVNMETARFFKSDFEENGSMDNVCLFLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHADVSNQLYACYAIGKDVQAMKAVVGEEALTSDDLLYLEFLQKFERNFIAQGPYENRTVFETLDIGWQLLRIFPKEMLKRIPQSTLSEFYPRDSAKH", "output": "Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). In renal intercalated cells, can partially compensate the lack of ATP6V1B1 and mediate secretion of protons (H+) into the urine under base-line conditions but not in conditions of acid load (By similarity)."}]}
+{"id": "function_test_2076", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLVHLFRVGIRGGPFPGRLLPPLRFQTFSAVRYSDGYRSSSLFWAVAHLRSQLWAHLPRAPLAPRWSPSAWCWVGGALLGPMVLSKHPHLCLVALCEAEEATPASSTPHVVGSRFNWKLFWQFLRPHLLVLGVAVVLALGAALVNVQIPLLLGQLVEIVAKYTRDHVGSFMTESQNLSTHLLILYGVQGLLTFGYLVLLSHVGERMAVDMRRALFSSLLRQDIAFFDANKTGQLVSRLTTDVQEFKSSFKLVISQGLRSCTQVAGCLVSLSMLSTRLTLLLMLATPALMGVGTLMGSGLRKLSRQCQEQIARAMGVADEALGNVRTVRAFAMEQREEERYGAELEACRCRAEELGRGIALSQGLSNIAFNCMVLGTLFIGGSLVAGQQLTGGDLMSFLVASQTVQRSMANLSVLFGQVVRGLSAGARVFEYMALNPCIPLSGGCCVPKEQLRGSVTFQNVCFSYPCRPGFEVLKDFTLTLPPGKIVALVGQSGGGKTTVASLLERFYDPTAGVVMLDGRDLRTLDPSWLRGQVVGFISQEPVLFGTTIMENIRFGKLEASDEEVYAAAREANAHEFITSFPEGYNTIVGERGTTLSGGQKQRLAIARALIKQPTVLILDEATSALDAESERVVQEALDRASAGRTVLVIAHRLSTVRGAHRIVVMADGRVWEAGTHEELLKKGGLYAELIRRQALDAPRTAAPLPKKPEGPRNHQHKS", "output": "ATP-binding subunit of the mitochondrial potassium channel located in the mitochondrial inner membrane. Together with CCDC51/MITOK, forms a protein complex localized in the mitochondria that mediates ATP-dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel) (By similarity). Plays a role in mitochondrial iron transport. Required for maintenance of normal cardiac function, possibly by influencing mitochondrial iron export and regulating the maturation of cytosolic iron sulfur cluster-containing enzymes (By similarity)."}]}
+{"id": "function_test_2077", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDVLELYRRTGALLEGHFLLRSGMHSPFFLQSAALLQHPLYAEAVGEALGKLFKDEKVDFVIAPAIGGVVLSFVVAKALGARALFAEKDGRGGMLIRKGLTVNPGDRFLAVEDVVTTGESVRKAIRAAEARGGVLVGVGAIVDRSGGRAAFGVPFRALLALEVPHYPEEACPLCREGVPLEEV", "output": "Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)."}]}
+{"id": "function_test_2078", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAGRQEKELQNVTLLGSEQTEYKYSYDPRVLETFDNQHPYRDYMVKFNCPEFTTLCPKTGQPDFATLYISYIPEQKMVESKSLKLYLFSFRNHGDFHEDSVNTIMNDLIELMDPRYIEVWGKFTPRGGISIDPYCNYGKKGTKYEEIANYRLMNHDLYPETITNR", "output": "Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)."}]}
+{"id": "function_test_2079", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKDLFKIYSNYQPAGDQPTAIASLIDGLESGLAKQTLLGVTGSGKTFTIAHVIQAMKRPTLIMAPNKTLAAQLYGEFKAFFPDNAVEYFVSYYDYYQPEAYVPASDTFIEKDASINEHIEQMRLSATKALIERKDAIIVATVSAIYGLGDPDSYLRMLLHLSRGEQSDQRKILKRLAEMQYTRTNLSLERGQFRVNGDVIDIFPADSEKEAIRIELFDDEVDNIARFDPLTGEILQRLPRVTIFPKTHYVTPRERILETVEKVKVELQERLAELNAQNKLVEAQRLEQRTCFDIEMMLELGYCSGIENYSRYLSNREAGEAPPTLFDYLPPEALLIIDESHVTVPQIGGMYRGDRARKETLVNYGFRLPSALDNRPLRFEEFEERSPQTIYISATPGPYEQEHSDNVAEQVVRPTGLIDPEVEIRPVKTQVDDLMSEIRQVIAQGSRILVTTLTKRMAEDLTEYLSEHGIKVRYLHSDVDTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVALVAILDADKEGFLRSERSLIQTIGRAARNVKGRAILYADNITGSMQRALTETERRREKQKAFNLKHGITPKGINKSVEDILEGAYIGKRKTMVAEQAPRYTHWSPQELAKQINALEKQMYAHAQNMEFELAAKIRDEYLLLKEQLMKI", "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage."}]}
+{"id": "function_test_2080", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGMDMIEMIEKAEILMEALPFIQKFYGKIFVIKYGGHAMIDEKAKNWTAQDVVLLKYVGINPVVVHGGGPEINKAMEKMGKKPEFVHGLRVTDEETLDIVEMVLAGKINGDIVSKLSKFGGKAVGLSGKSGRIILAKKKLKKIKTEKGEEIEVDLGRVGETVEVNTELLEILINNGYIPVVSPIGLDEKGEAYNLNADTVAGDIAGALKAEKLILITDVDGIMDDINNPETLHRKLTASELKEMIEDGRIKGGMIPKAESALYALEHGVKSVHIINGKIPHALLLEIFTEEGIGTMITRD", "output": "Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate."}]}
+{"id": "function_test_2081", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVSKAEKPKQSGMFSVESLLETTTPQKSSVKDENLLKPPAPITPKTPLMLPGLHHMAPYFGAQLDPVMIYFSQTGNRLPVMSSDSSPESSASSPLSMQHHTLPWLSSQREDSPTSDDAKIQIGLTKCMLRKHKNNRKPRTPFSTQQLISLERKFQSKQYLSIAERAEFSASLQLTETQVKIWFQNRRAKSKRLQEAEVEKVKFAQVSAYAAAVNDPSLMAFYPGQW", "output": "Probable transcription factor needed for the proper production of touch cell precursors. Essential for embryonic morphogenesis (By similarity)."}]}
+{"id": "function_test_2082", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRSIIADSKRLVVKVGSSLVTNDGRGLDHDAIGRWAAQIAALRGAGKEVVLVSSGAIAEGMQRLGWSKRPREIDELQAAAAVGQMGLAQVYESRFAEHGIRTAQILLTHADLADRERYLNARSTLLTLLRLGVVPIINENDTVVTDEIKFGDNDTLGALVANLIEGDTLVILTDQPGLFTADPRKDPGATLVAEASAGAPELEAMAGGAGSSIGRGGMLTKILAAKRAAHSGANTVIASGRERDVLVRLAAGEAIGTQLIARTARMAARKQWMADHLQVRGHVVIDAGAVDKLTAGGKSLLPIGVVAVQGVFARGEVIACVDDTGREVARGITNYSSAETKLIQRKPSGEIETVLGYMLEPELIHRDNLVLV", "output": "Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate."}]}
+{"id": "function_test_2083", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSIKSDKWIRRMAEEHKMIEPFVPDQVRAAEDGRKIVSYGTSSYGYDIRCADEFKIFTNINSTIVDPKNFDEGSFVDFKGDVCIIPPNSFALARTVEYFRIPRTVLTVCLGKSTYARCGIIVNVTPFEPEWEGYVTLEFSNTTPLPAKIYANEGVAQVLFFESDEVCDVSYADRGGKYQGQRGVTLPKT", "output": "Catalyzes the deamination of dCTP to dUTP."}]}
+{"id": "function_test_2084", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNRTKLVLGAVILASTMLAGCSSNAKIDQLSSDVQTLNAKVDQLSNDVNAVRADVQAAKDDAARANQRLDNQAQAYKK", "output": "A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane."}]}
+{"id": "function_test_2085", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MARAQNEAASEVDGVLNLLKPPGMTSHDVVAFVRRALGVKKAGHTGTLDPGVAGVLPVCVGRATRLAEYIAGSDKAYRAEITFGVATDTQDGFGEVVAEADASHLTRGDVAYALTRFHGPIEQVPPMVSAVKVGGKRLYELARKGVEVEREPRRVFIHRLQLLDFRPGPRPVAYIDVVCSKGTYVRTLAHDLGRFLQVGAHLSYLVRTRSGPFVLAQAATLEELAAGKARLLPPAAALGDMPRVTVSGRAAARVLHGVAPAVRVEHPDGTTVAVVAANGALLALAEADGGGLRLRKVFG", "output": "Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs."}]}
+{"id": "function_test_2086", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSLCTLEINLSAIKNNYRLLQDICTTALVGAAVKANGYGIGAMQIAKALIEENCQYFFVATSEEGINLRKALNNDITILVLNGVFTHDALELIQYNLTPVLNNLKQIEIWQKFSNLKEKILPCYLHFNTGLNRFGLNYDEIEQLINDRDLLKGLDLQYIISHLAASEEMDNPYNLAQLNRFKDYLEYFPNVKASLANSGGIFLGQDYHFDLARPGAALYGLNSLIEVSYNLSYKEKFERNTPALATTVCINKCADVNTRLTYKVPLKGSYRLQNPVTLKAPIIHLQNLTLDSHIGYNMTFTTKRDSIIATLPLGYADGFSRNFSNQGEVFINSRSVPIVGRVSMDLINIDVTDLPPSEVFLGQEVEIIGNYCTPDKIASIIGTVGYEVLTSLGSRYKRKYIS", "output": "Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids."}]}
+{"id": "function_test_2087", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MADMLTIAGKTFSSRLFIGTGKFASPEIMRDVLQACKSQMVTVALRRVNLADPEDDIMSQIDTGETNFLPNTSGARNAEEAIRLAELARAGSGTNWVKIEVVPDPRTLLPDPIETLKATEELVKRGFIVLPYMNVDPILALRLQDVGAAAVMPLAAPIGTNLGITNRLQLEMIIEQARVPVVIDAGLGAPSHAALAMELGADAVLVNTAIAVADKPVAMAEAFAMATIAGRAAYLAGLGSQCPVASASSPVSGNITVDLDFLD", "output": "Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S."}]}
+{"id": "function_test_2088", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSKDELKDKKRKVEDEELKSKKKLKKDKKDKKDKKDKKDKKDKKEKKEKKEKKDKKSETESFAASASQSDIDEFLKENEVTVSDPSGSNIVPYLDFSQVSFIDQIQKEISKFPKPTPIQAVSWPYLLAGKDVIGIAETGSGKTFAFGVPAINNIVTSGDKSSSVKVLVISPTRELASQIYDNLIVLTDACGLRSCCVYGGVPKDQQREDLRRSQVVVATPGRLLDLIEEGSVDLSHVNYLVLDEADRMLEKGFEEDIKKIIRQTRSTSRQTLMFTATWPKEVRELASSFMSEPVKVSIGNRDELSANKRITQIVEVVDPFRKEKKLLELLKKYHSGPTKNDKVLIFALYKKEASRVERNLKYNGYDVAAIHGDLSQQQRTQALNEFKAGKCNLLLATDVAARGLDIPNVKTVINLTFPLTVEDYVHRIGRTGRAGQYGTAHTLFTEQEKHLAGALVNVLNGAGQPVPEELKKFGTHTKKKEHSAYGAFFKDVDLSKKPKKITFD", "output": "ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity)."}]}
+{"id": "function_test_2089", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTRVGLRIDVDTWRGTRDGVPALLKVLAEFDIQASFFFSVGPDNMGRHLWRLLRPRFLWKMLRSNAASLYGWDILLAGTAWPGRHIGARFGSLIRQTHDAGHEVGLHSWDHHGWQANVARWSDAQLAAQFHEGMDALTQILPSPVRCSAVAGWRADARVVEMKQRWNLDYNSDCRGTQPFRPRLKNGGLGTTQIPVTLPTYDEVIGERVSDGEFNDFILDAIEQDRGVPVYTIHAEVEGGAKLALFRQLLLLARQRHIEFCPLSSLLPDDSTTLPVGRIERAPFPGREGWLGVQTEE", "output": "Catalyzes the deformylation of 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides."}]}
+{"id": "function_test_2090", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSEIITVKRLFSDAKIPVRHSEGAAAYDLYAYEDTVVAPNERKVIATGVRITVPLSCQGTIYSRSGLALKYCIEIFGVNIGPGETKDIVVDIYNHGKMPFNVAKGDRIAQIVFIKLFGGDLHEVSELSDTKRGSCGWGSTGIS", "output": "This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA."}]}
+{"id": "function_test_2091", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MMRFSKIIFLAFLFAISCLTVPLFAETAPVSARKDNRIRFVNYDPYNVTQIIGSIRSSVQLEFADDEEVTYVGIGNSVAWQVAPAGHFVFLKPREVQPVTNLQIVTSRQDGTKRSYQFELQVREGDVSAGNDTYFLVKFRYPEDEALRKKLAKAAEAAQREENFVNDVFNIHENFGPRNWAYEAQGSSLIEPASVYDNGKTTTFTFLGNTEIPAIYLVSLDGQESLVPKSIKGNKVIVHAIAAQFTLRRGNDVLCIFNKRFVPEGINPETGTTSPSVQRRVNIGNGHEG", "output": "Component of the type IV secretion system VirB/VirD4 which could be a major virulence determinant for subversion of human endothelial cell (HEC) function."}]}
+{"id": "function_test_2092", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEKYILSIDQGTTSSRAILFNQKGEIAGVAQREFKQYFPQSGWVEHDANEIWTSVLAVMTEVINENDVRADQIAGIGITNQRETTVVWDKHTGRPIYHAIVWQSRQTQSICSELKQQGYEQTFRDKTGLLLDPYFAGTKVKWILDNVEGAREKAENGDLLFGTIDTWLVWKLSGKAAHITDYSNASRTLMFNIHDLEWDDELLELLTVPKNMLPEVKPSSEVYGKTIDYHFYGQEVPIAGVAGDQQAALFGQACFERGDVKNTYGTGGFMLMNTGDKAVKSESGLLTTIAYGIDGKVNYALEGSIFVSGSAIQWLRDGLRMINSAPQSESYATRVDSTEGVYVVPAFVGLGTPYWDSEARGAIFGLTRGTEKEHFIRATLESLCYQTRDVMEAMSKDSGIDVQSLRVDGGAVKNNFIMQFQADIVNTSVERPEIQETTALGAAYLAGLAVGFWESKDDIAKNWKLEEKFDPKMDEGEREKLYRGWKKAVEATQVFKTE", "output": "Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate."}]}
+{"id": "function_test_2093", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTKTKIMGILNVTPDSFSDGGKFNNVESAVTRVKAMMDEGADIIDVGGVSTRPGHEMITVEEELNRVLPVVEAIVGFDVKISVDTFRSEVAEACLKLGVDIINDQWAGLYDHRMFQVVAKYDAEIVLMHNGNGNRDEPVVEEMLTSLLAQAHQAKIAGIPSNKIWLDPGIGFAKTRNEEAEVMARLDELVATEYPVLLATSRKRFTKEMMGYDTTPVERDEVTAATTAYGIMKGVRAVRVHNVELNAKLAKGIDFLKENENARHNFS", "output": "Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives."}]}
+{"id": "function_test_2094", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNILVVKTPEELAEAGYKLIEEVVKTKENPTLGMATGSSPLGIYAEMRKNKLDTSRVTTVNLDEYVNLPHEDKNSYHYFMQEQLFDHLPFKQTYVPNGMASDLEEECKRYEGILAANPVDLQILGIGENGHIGFNEPGTPFNSPTNIVELTESTRQANLRFFEKEEDVPTHAITMGIGSIMKAKQILLVAMGSKKAEAVKELLQGAYSEACPATVLQRHPNVTVIADQEALSLCSEAIADEHRQVFTISDLLSDSRVGETAN", "output": "Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion."}]}
+{"id": "function_test_2095", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSGIIATYLIHDDSHNLEKKAEQIALGLTIGSWTHLPHLLQEQLKQHKGNVVHVEELAEHEHTNSYLRKKVKRGIIKIEYPLLNFSPDLPAILTTTFGKLSLDGEVKLIDLTFSDELKKHFPGPKFGIDGIRNLLQVHDRPLLMSIFKGMIGRNIGYLKTQLRDQAIGGVDIVKDDEILFENALTPLTNRIVSGKEVLQSVYETYGHKTLYAVNVTGRTFDLKENAKRAVQAGADILLFNVFAYGLDVLQSLAEDDEIPVPIMAHPAVSGAYSASKLYGISSPLLLGKLLRYAGADFSLFPSPYGSVALEKEEALAISKYLTEDDVFFKKSFSVPSAGIHPGFVPFIIRDFGKDVVINAGGGIHGHPNGAQGGGKAFRTAIDATLQNKPLHEVDDINLHSALQIWGNPSHEVKL", "output": "Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)."}]}
+{"id": "function_test_2096", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQGLKSAISFFTIIPVKADLNKNIVFFFTITGAITGLMAASIFYLTSFINQLLASVASVSFLIIIYGFNHADAVLDLGDTFMVHDPEKKKIIIKDVYHGTGSVVTFFIIYIITISLLSSFNSIQGSIALILSETISRFSMLMSMYKSNSFSGGISEIFISYFDKPFKITFFNFLVIILIFLIFYKYIIFTMFSLISIVISYYFKSHEQKIFNGINGDIIGFTGELSRLISLLLILISFKLI", "output": "Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate."}]}
+{"id": "function_test_2097", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTTINKNEFLLEMTGISKEFPGVKALDKVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYEKNEGDIVFLGKSINFSSSKEALEAGVSMVHQELNQVLQRTVMDNIWLGRYPTKGFFVDQKKMYEETKKVFEELDIDIDPNVKVATLSVSQMQMLEIAKAFSYDAKIVIMDEPTSSLTEKEVNHLFKIIKKLKEKGCGIVYISHKMEEIFEICDEITILRDGIWVDTRPLEGLTMDQIIGMMVGRELTQRFPEKTNTPKETILAVKNLTALNQPSVNDVSFELRKGEILGIAGLVGAKRTDIVETLFGIRERSSGDIILHGKHLKNKDAHEAINNGFALVTEERRSTGIYSNLDITFNSLVANVEQYKEGFGLLSNRKMKSDTQWVIDAMSVKTPSHKTMIGSLSGGNQQKIIIGRWLLTGPEILMLDEPTRGIDVGAKFEIYQLILELANKDKGIIIISSEMPELLGITDRILVMSNGRAAGIVETKNTTQNEILSLASRYL", "output": "Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system."}]}
+{"id": "function_test_2098", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDIKAYFELIRLKNCLTASFGAFIGGLIASYFNLAMVDNLILASIVVFLVCGFGNALNDIYDLKIDRINKPKRPIPSKRITLNNAKVFSYSLVVMGLFISLFNISCFLMAVLNSIVLQQYASTYKKNKIIGNLIVAYLTGSVFIFGGIAVGNIDVTIMLFLCALFAMWSREIIKDYEDIEGDLKEKVISIPIKCGERSIYIAAFLLIFAIFLSPLPYLFGFFGIYYMISVVFCDLLFLFGIYKLVFNPSKMEAKKASRNIKIVTNLVLIAFLIGSLFK", "output": "Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids."}]}
+{"id": "function_test_2099", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTEFRSGFVCLVGRPNTGKSTLTNALVGTKVAITSMRPQTTRHTIRGIVHREDFQIILVDTPGLHRPRTLLGKRLNDLVRDTYAEVDVIGLCIPADEAIGPGDRWIVEQIRATAPKTTLVAIVTKIDKVPKDRVAAQLVAVSELVGDSAEIVPVSAVTGAQVDIVIDVLAAALPPGPAYYPDGELTDEPEEVLMAELIREAALEGVRDELPHSLAVVIDEVNPREDRDDLIDVHALLYVERDSQKGIIIGKGGARLREVGTAARAQIEKLLGTKVYLDLRVKVAKNWQSDPKQLGRLGF", "output": "Exhibits GTPase activity. Binds RNA but is probably not involved in ribosome assembly in mycobacteria."}]}
+{"id": "function_test_2100", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKINNLPEVFTAALPVLKEINEAGYEAYFVGGSVRDLLLNRHIHDVDIATSAYPMEIKQIFKKTIDTGIKHGTVTVLYEGESYEITTFRTESGYQDFRRPDHVTFVQNLSEDLKRRDFTINALAMDVDGNIIDHFDGLGDLEKHLIRAVGKAENRFHEDALRMMRAVRFMSQLQFTLEPETEQAISDNHELLSKISVERIRDEFVKMGIAPGSQKAFQIFLDTGLSEEVPGFRGKKENLALYPQLNFSPTTEANLWALMIILLKLPNDKIPHFMRMWKNSNAMERQVADIVAFFDLISSHAPNNYDLYKAGLETIVSTIDLAHILGQPVNGSALVDSYEALPIKNNRDLVIDGHFLLKNGIPAGPRVGLLLEEIKKAVLEGVISNNEAAITEFISLNH", "output": "Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate."}]}
+{"id": "function_test_2101", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKIKFEIKYKDAAGKVGKIKLNGKTIETPYLFPVINPFKQELPIKEIKKMGFNAIITNAYILFKRKEEVMEKGIHNFLGFDGIIETDSGAYQLLQYGDIDIENEDIIYFQNEIGVDIGNILDIPSYGKTYEEAKKDLEITLERLKQAIEMANFAINGPIQGDKYLDLRYKALEEVSKLDIDIYAIGGIVPYMNQYKIESLAKIIGPLLLDIPRDRPVHLFGLGHPLIMPLFVALGADLFDSASYSLFAKEERILTPFRTFRLEDLTDSYILDYKASELKGMENKTYIIAKHNLLVLRNEINFIRDLIRQNRLWDYVIIKAHAHPSIYFATKYVLENLYEKLKEHEPITKRVGILYQGELTELRSDLRYAIEQLKKLDKSQINDILDYAWPFGQFEIGEKDKKLFFQRFLK", "output": "Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs."}]}
+{"id": "function_test_2102", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQRDYTATEVFQESGPDAIVYLHGGAWIDVRNSPRDFAELAARVREDAPLASQYAVTYRLSPEVQHPVHVADCVEHISQLIVEKGIRKLHLLGHSVGATLCWQILTALPGDRRYPEGPDFAMKLALVRSSLAHVFLVDGIYSLRALLEEYPDYDYFVNKAFKSLKDFEDPSESAERISAGPILHVIHSYKDELLTLKQTQYLTAVLTAHQIPYKLYVDDLGLHEDVYRNEKVAAYIVAQLP", "output": "Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites."}]}
+{"id": "function_test_2103", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKKPFRIGFGFDVHRLSEGYPLWMGGVRLEHSKGLEGHSDADVLIHAICDALLGAAALRDIGYHFPPSDPQYKGIDSKILLARVMELVRSQGYELGNIDATIAAEQPKLNPHIPDMQRVLAEVIQVEVSDISLKATTTEKLGFTGREEGISAYAVALLIAAV", "output": "Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)."}]}
+{"id": "function_test_2104", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVVEGGMTSLERSQILTEEQYLDALEEFGDEFDAKMGAEAIQSLLKNLDLENECETLREELNETNSETKRKKLTKRIKLLEAFIQSGNKPEWMVLTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPASGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERVYRAGLASLHARVKVRITEEVKDGEGNITTNTGLVDTTIGRAILWMIVPRGLPYSLVNQPLGKKAISRMLNTCYRVMGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKAGIIAEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANERVAKAMMENLSTETVTNRDGEEEQQVSFNSIFMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHDGILMTPVIEGGDVKEPLRERVLGRVTAEDVLKPGTADILVPRNTLLNEKWCDLLEESSVDSIKVRSVVSCETDFGVCANCYGRDLARGHIINKGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVRNKGSLKLFNAKSVTNSAGKLVITSRNTELCLIDEFGRTKESYKVPYGAVLGKGDGETVNGGETVANWDPHTMPVVSEVSGIIRFADMIDGQTITRQTDELTGLSSLVVLDSAERTGSGKDLRPALKIVDAKGDDVLIPGTDMPAQYFLPGKAIVQLDDGVSISAGDTLARIPQESGGTKDITGGLPRVADLFEARRPKEPAILAEVSGIVSFGKETKGKRRLVISPLDGGDAYEEMIPKWRQLNVFEGEVVERGDVISDGPESPHDILRLRGVHAVTRYITNEVQEVYRLQGVKINDKHIEVIVRQMLRKATIESAGSSEFLEGEQVEYARVKVANRKLEQEGKVAATYGRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRIRRRQLNEPAEAPQVSVDEATANLAELLNAGFGGDKK", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_2105", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPSKAKVAIVGSGNISTDLLYKLLRSEWLEPRWMVGIDPESDGLARAAKLGLETTHEGVDWLLAQPDKPDLVFEATSAYVHRDAAPKYAEAGIRAIDLTPAAVGPAVIPPANLREHLDAPNVNMITCGGQATIPIVYAVSRIVEVPYAEIVASVASVSAGPGTRANIDEFTKTTARGVQTIGGAARGKAIIILNPADPPMIMRDTIFCAIPTDADREAIAASIHDVVKEVQTYVPGYRLLNEPQFDEPSINSGGQALVTTFVEVEGAGDYLPPYAGNLDIMTAAATKVGEEIAKETLVVGGAR", "output": "Involved in cholesterol degradation. Catalyzes the conversion of propanal to propanoyl-CoA, using NAD(+) and coenzyme A."}]}
+{"id": "function_test_2106", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKLELIWVIYKSGSKSAKEEALLCSRNIESLGIKVITAESGPLLNTCNNILNPNKQIPTLVIVLGGDGTVLGAARHLAMYEVPILSFNVGGNLGFLTHDRQLLKDESLWSRIQEDQFAIESRMMLKGRVESYLDTNDVGKKENFFWALNDIYFRSCSEDISPTCTLELKIDDEDVDIYRGDGVILSTPTGSTAYSMATGGPILHPGIEAIIVSAICPMSLSSRPIVVPAGSRLIIKPVGNKNQRVNIWQDGVSSALMQKGEQCVIEKARNHAQMLILEQSPSYFRTLTQKLHWAGSLVDNQNKMAPK", "output": "Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP."}]}
+{"id": "function_test_2107", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSKQFGKVGVLYGGRSAEREVSLMSGKGVHEALLSAGVDAHLFDTGERSLADLAAAGFERVFIALHGRYGEDGTLQGALELLGIPYTGSGPLASSLSMDKIMTKRVWLQHGLPTPAFEVLGGSTELRLVPDRLGLPLILKPPHEGSTVGITKVAGYSDMKAAYELAARFDAEVLAEQFITGRELTVAVLGSGAAARALPVIEIVAPGGNYDYEHKYFSDDTQYFCPADLPADVAADVAAVAERAYAALGCEGWGRVDFILDRENRPWLLEMNTSPGMTGHSLVPMAARAVGMSYADLCVAILAEAACKVRSPARQD", "output": "Cell wall formation."}]}
+{"id": "function_test_2108", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MESESESGAAADTPPLETLSFHGDEEIIEVVELDPGPPDPDDLAQEMEDVDFEEEEEEEEGNEEGWVLEPQEGVVGSMEGPDDSEVTFALHSASVFCVSLDPKTNTLAVTGGEDDKAFVWRLSDGELLFECAGHKDSVTCAGFSHDSTLVATGDMSGLLKVWQVDTKEEVWSFEAGDLEWMEWHPRAPVLLAGTADGNTWMWKVPNGDCKTFQGPNCPATCGRVLPDGKRAVVGYEDGTIRIWDLKQGSPIHVLKGTEGHQGPLTCVATNQDGSLILTGSVDCQAQLVSATTGKVVGVFRPETVASQPNVGEGEESESNSVESLGFCSVMPLAAVGYLDGTLAIYDLSTQTLRHQCQHQSGIVQLLWEAGTAVVYTCSLDGIVRLWDARTGRLLTDYRGHTAEILDFALSKDASLVVTTSGDHKAKVFCVQRPDR", "output": "Plays a role in angiogenesis and cell migration. In smooth muscle cell migration, may act through the RhoA pathway (By similarity)."}]}
+{"id": "function_test_2109", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAGVEDWISAPLAVVQGLFSQRQANGDWEKNVTDYFHDKLQGNRSPASVPCLNDVPLHYLKPNSLVRFRCMVQDMFDPEFYMGVYETVDTNTSARVLHFGKYRDLAESLPQQEVDLDSRRNVTCERQTFYCVPVPGESPWVKDAYTSSSQARACASTSYTPSRQKRSYEEDEDVGPCDTRTSHGLGEPKRLETEAAGLQQNQPSSCSSAPDLNFPLPGEKGPACLIKVYEGWDSFKVNDIIEVYGILSVDPALSAVNEDRDAVSALLDPSDNMETLEEQRAHCPPASLVPRIHSVVTWKLQHNNPLLPGTLQGTEESKLFVSNLLCEVSAVRAELLGFLSHALLGDSLAAEYLIIHLISTVYARRDVLPLGKFTLNLSGCPRNGIFSELLYRILQQIVPAAHYLPMTIENMNKLRFIPHKDYNANRLRSGLLQLSAHTSLLLDETLLEQGQLDTAGVHNVTALGNLITWQKVDYDFSYHRMEFPCNINVLVTSEGRSLLPSDCRVHLQPQMTPPNLEQYMGALLSASLPSLLNKFRSYIGLLRLLDYSISDEITKAVEDDFVEMRKNDPQSISADDLHRLLVVSRLLSLSSGQTTLSREMWLRAKQLEQQRKSRFREQKHVNGNEL", "output": "Associated component of the MCM complex that acts as a regulator of DNA replication. Binds to the MCM complex during late S phase and promotes the disassembly of the MCM complex from chromatin, thereby acting as a key regulator of pre-replication complex (pre-RC) unloading from replicated DNA. Can dissociate the mcm complex without addition of ATP; probably acts by destabilizing interactions of each individual subunits of the MCM complex. May also be required for sister chromatid cohesion."}]}
+{"id": "function_test_2110", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKKQRVVVKIGSSSLADSHGGISTEQLSDHVAALARLKEDGHEVVLITSGAVAAGFSALGYPSRPVTIKGKQAAAAVGQSLLMQAYTEEFRKYGIVTAQLLLTRSDFSRKEQYSNAYATLGELLNRSALPIINENDSISLEELTFGDNDMLSALVSGLVSADMLMIFTDVNGLYDKNPQKNADAKKYYFLPEVTEEISSLAGDAGSKLGTGGMKSKIDAAKTALSLGVSVFIGTGRGQEKFVNVLKGKGDGTYVGNAPQKEMKMNKQWIALHSLVSGQIEVDAGAATAIIQHGKSLLPAGVTNVSRFFQVGEVVEVVTQQGRVIGKGQCTYSAEELIDVKGMQSQDIQVRGERHSYEVIHRDHWVSL", "output": "Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate."}]}
+{"id": "function_test_2111", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MVAVIIKGNEVAEKKRAQLKEEVVKLKEQGIVPGLAVILVGEDPASRSYVKGKEKGCEQVGIYSELIEFPETITEERLLAEIDRLNGDDRINGILVQLPLPKHIEEKAIIERISPEKDVDGFHPISVGRMMTGQDTFLPCTPHGIVELVKETNLDISGKHVVVIGRSNIVGKPVGQLFLNENATVTYCHSKTQNMKELTKLADILIVAVGRPKMVTADYIKEGAVVIDVGVNRLETGKLCGDVDFDNVLDVASYITPVPKGVGPMTITMLLHNTVESAKRAGVVCK", "output": "Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate."}]}
+{"id": "function_test_2112", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIQTKDIIELTDTYGANNYHPLPIVISKAEGVWVEDPEGNRYMDLLSAYSAVNQGHRHPKIINALIDQANRVTLTSRAFHSDQLGPWYEKVAKLTNKEMVLPMNTGAEAVETAIKTARRWAYDVKKVEANRAEIIVCEDNFHGRTMGAVSMSSNEEYKRGFGPMLPGIIVIPYGDLEALKAAITPNTAAFILEPIQGEAGINIPPAGFLKEALEVCKKENVLFVADEIQTGLGRTGKVFACDWDNVTPDMYILGKALGGGVFPISCAAANRDILGVFEPGSHGSTFGGNPLACAVSIAALEVLEEEKLTERSLQLGEKLVGQLKEIDNPMITEVRGKGLFIGIELNEPARPYCEQLKAAGLLCKETHENVIRIAPPLVISEEDLEWAFQKIKAVLS", "output": "Catalyzes the interconversion of ornithine to glutamate semialdehyde."}]}
+{"id": "function_test_2113", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRVIGLMSGTSYDAIDAAAADLGLAGDRLVLKPLGLMSEAYDSGLREELAAALPPAATSLAGVCRLDTRIGQAFAAAAVRADRELCGGRAELVASHGQTVYHWAEAGRVYGTLQLGQPAWIAEATGLPVVADFRPRDIAAGGQGAPLVSLVDLLWLRGRAGTSVALNLGGIANLTAPDGTAFDTGPACALIDAAAHGLSGGRLDHDVDGALAARGTVHEPMLRRLLAEPYYALPAPKTTGKELFHLGYLRDALAGFGTLTAEDVIATLTRLTALTVADAVRAVRATEVVASGGGTRNPVLMEMLARELGAVALRTSDELGLPSAAKEAYAFAVLGFLTVHGLAGTDPVSTGARHPSVLGSVTPGRDGLRLPPRADWSPVRLVLE", "output": "Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling."}]}
+{"id": "function_test_2114", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSEFLPFSRPAMGVEELAAVKEVLESGWITTGPKNQALEQAFCQLTGNQHAIAVSSATAGMHITLMALEIGKGDEVITPSLTWVSTLNMISLLGATPVMVDVDRDTLMVTPEAIESAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVGTYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDRQTWGRAPQAEVLTPGYKYNLTDINAAIALTQLVKLEHLNTRRREIAQQYQQALAALPFQPLSLPAWPHVHAWHLFIIRVDEQRCGISRDALMEALKERGIGTGLHFRAAHTQKYYRERFPTLSLPNTEWNSERICSLPLFPDMTTADADRVITALQQLAGQ", "output": "Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides."}]}
+{"id": "function_test_2115", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIDTTLPLTDIHRHLDGNIRPQTILELGRQYNISLPAQSLETLIPHVQVIANEPDLVSFLTKLDWGVKVLASLDACRRVAFENIEDAARNGLRYVELRFSPGYMAMAHKLPVAGVVEAVIDGVREGCRTFGVQAKLIGIMSRTFGEAACQQELEAFLAHRDQITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAIEDRALMDFLAEQQIGIESCLTSNIQTSTVAELAAHPLKTFLEHGIRASINTDDPGVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLSAEEKRALREKVAAK", "output": "Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine."}]}
+{"id": "function_test_2116", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTGPLGAGPQALPAAPLEDWLRERYFQAKTDISSSGVHNYTFGELRALDPALLGTRELDQLMFRDGPSLGDERLRAAVAARVRPGPGHVVMTTHGSSEALYLAFAALVRPGDEVVVATPAYHSLSGLATAAGASLRPWPLRPENGFAPDLDDLRAVLSDRTRLVVVNFPHNPSGACVDPRGRTELLDLVANSQAVLLWDGAFTDLVHDHPPLAEPSQDLDRVLSFGTLSKAYGLPGLRVGWCVVPQDLVSELVRIRDYLTLSLSPLVERVAAVAVEHADALITPRLTEARHNRRRVLEWAAASEGAIDCPVPRGGVTAFPRFTAHTDVTDLCERLLARHGVLVVPGRVFGQADRMRIGFSCPRPELERGLAAISEELGTHARGRRRGTG", "output": "Involved in the biosynthesis of capreomycidine, an unusual amino acid used by non-ribosomal peptide synthases (NRPS) to make the tuberactinomycin class of peptide antibiotic such as viomycin and capreomycin. Catalyzes the dehydration of the C3 hydroxyl of (3S)-hydroxy-(2S)-arginine and the intramolecular cyclization to yield (2S,3R)-capreomycidine."}]}
+{"id": "function_test_2117", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSRVSEQPVDRITIPLLQRWKQDGRRLVMTTAYDAVAAPIPDPSIDISLVGDSGGNVCLGFENTPPVSVAMMNHHLEAAVRSKPRALLVADMSFLSFHVSVEETIRNAGGFLQRGAAAARLEGGGKRIEMVRAIVDCEIPVMGHLGLVPQSVNVMGGFKVQGRKVDEALRLLDDAHRLQEASCFALVLEGTPAELTARVSDSLTIPTIGIGSGPDCSEQVLCFMTCWAKPKVIAPNSFPPIRKAFSSSMMRFRAGQRMSAVARSPARKSPIGFPKALGRQLPTGRHPPQIITSVAELRRTLAKSRSANQRAGLCRRWAISTMATWR", "output": "Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate."}]}
+{"id": "function_test_2118", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKRTIAIVAGGDTSEFHVSLRSAQGIYSFIDKEKYTLYIVEMQGTRWEVQLPDGAKAPVDRNDFSFMLGTEKIRFDFAYITIHGTPGEDGRLQGYFDMMHIPYSCCGVLAAAITYDKFTCNQYLKAFGVRIAESLLLRQGQSVSDEDVMEKIGLPCFIKPSLGGSSFGVTKVKTKEQIQPAIVKAFEEAQEVLVEAFMEGTELTCGCYKTKDKTVIFPPTEVVTHNEFFDYDAKYNGQVDEITPARISDELTNRVQMLTSAIYDILGCSGIIRVDYIVTAGEKINLLEVNTTPGMTTTSFIPQQVRAAGLDIKDVMTDIIENKF", "output": "Cell wall formation."}]}
+{"id": "function_test_2119", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKQYLDLLNRVLTEGTEKSDRTGTGTISVFGHQMRFNLDEGFPCLTTKKLHLKSIIYELLWFLQGDTNAKYLQEHGVRIWNEWADENGDLGHIYGYQWRSWPDYDGGFIDQISEAVETIKHNPDSRRIIVSAWNVADLKNMNLPPCHAFFQFYVADGRLSLQLYQRSADIFLGVPFNIASYALLLQMMAQVTGLKAGEFIHTLGDAHIYLNHLDQVKLQLSREPRALPQMKINPDVKSIYDFQFEDFELVNYDPHPHIAGIVAV", "output": "Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis."}]}
+{"id": "function_test_2120", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDNERQKALDTVIKNMEKSFGKGAVMKLGDNKGRRVSSTSSGSVTVDNALGVGGYPKGRIIEIYGPESSGKTTVALHAIAEVQKNGGVAAFIDAEHALDPVYAQALGVDIDNLYLSQPDHGEQGLEIAEAFVRSGAVDIVVVDSVAALTPKAEIEGEMGDTHVGLQARLMSQALRKLSGAISKSNTTAIFINQIREKVGVMFGNPETTPGGRALKFYSSVRLEVRRAEQLKQGQDIVGNRTKIKVVKNKVAPPFRVAEVDIMYGQGISKEGELIDLGVENDIVDKSGAWYSYNGDRMGQGKENVKNYLKENPQIKEEIDRKLREKLGIFDGDVDENENEDDSPKTLFDE", "output": "Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage."}]}
+{"id": "function_test_2121", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MHKPIKKLGQNFLKDKKIIKKIINFINPKYKDKIIEIGPGLGALTIPISKISKSITAIEIDKNLVYFLNKNKNIKNNLNIINIDIMKLNLKKFFSSFCDPVRIFGSLPYNISVSLMFNFIENYNKIIDMHFVIQKEVAQRILARPNNKHYGYISVIMQYYFYVEKLIDISNCAFKPIPKVQSSLIRMRPHKVCPFPFCDIDKMKVLLKSAFNQRRKMLKNSLKKYFSVEQIILYKINPKLRAENLSIENYCNLSNNMIIKK", "output": "Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits."}]}
+{"id": "function_test_2122", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAIKAGTELGKQAKAVIDAGQLVSDEIILGLIKERIAQEDCAKGFLLDGFPRTIPQADGLKEMGVAVDYVIEFDVADDVIVERMAGRRAHLPSGRTYHVVYNPPKVEGKDDVTGEDLVVRDDDKEETVRARLGVYHSQTAPLIEYYGKEAAEGNTKYLKFDGTKQVAQVSADIEKALA", "output": "Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism."}]}
+{"id": "function_test_2123", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLRIITQLTDLRAELRRICDRTDSGEMSEQQATVEAILRRVAKDGDRALIEYTAQFDHIDLTPETLRVKGDELDAAYQQVSKELLDAIRLAKQQIEAFHRQRVPKSWVQFGEDGVVLGKRYTAVDAAGLYVPGGRAAYPSTVLMNAIPAQVAGVQRIVMVTPPGQGKGINPAVLVAAQEAGIQEIYRVGGAQAIAALAYGTETIPRVDVITGPGNLYVMLAKKQVYGRVGIDSLAGPSEVLIIADEAAHPAQIAADLLAQAEHDPLAAAILLTPSLSLAKAVVTAVNEQLADHPRRVLTEKAIAHYGLIGIVETLEQAVELSNSFAPEHLELEVEDPWSLVEQVRHAGAIFLGYSTPEAVGDYLAGPNHTLPTSGAARYASALGVETFLKHSSIIQYTPAALRKQGGAVMTLAETEGLISHRDSVRLRLQP", "output": "Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine."}]}
+{"id": "function_test_2124", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGKFQIISHPLIQHKLSILRRKDTSTKHFRELVNEIAMLMGYEVSRELPLEEVEIETPITKTVQKQLTGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGMYRDEETLEPVEYLVKLPEDIDQRQIFVVDPMLATGGSAVLAIDSLKKRGAANIKFVCLVSAPEGLKKLQEAHPDIDIYTAALDEKLNEKGYIVPGLGDAGDRLFGTK", "output": "Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate."}]}
+{"id": "function_test_2125", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSESNVKHLISWEDWSDSEILDLLDFAIHVKKNRVNYAGHMSGRSLAMLFQKTSTRTRVSFEVAMTEMGGHGIYLDWMASNFQLSDIDLEARYLSRNVSVIMARLKKHEDLLTMRNGSQVPLINGCDNMFHPCQSLADIMTIALDKPEIPLNQIQLTYIGVHNNVVNSLIGITSALGIRLTLVTPIAEKENIHSQTVERAKAKGTLSWEENLKKAIQNADYVYTDTWLDMEFFNDPSYADKKKQRMELMMPYQINSSLLEKTNAKVMHDMPIHAGYEITREVVLGPRSIIFQQAENRLDAQKAVILKLLEA", "output": "Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline."}]}
+{"id": "function_test_2126", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVELAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA", "output": "Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate."}]}
+{"id": "function_test_2127", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNETLAPLYLDKVRGVLEQAGVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPPRELASGLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIITLLTRAGLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLILPLAIGKSEVRSGVSHELVLNAIADCQSA", "output": "Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)."}]}
+{"id": "function_test_2128", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKKISLPKIGIRPVIDGRRMGVRESLEEQTMNMAKATAALLTEKLRHACGATVECVISDTCIAGMAEAAACEEKFSSQNVGLTITVTPCWCYGSETIDMDPTRPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLLRFARAGLAVASMKGKSYLSLGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRIDQKIYDEAELEMALAWADKNFRYGEDENNKQYQRNAEQSRAVLRESLLMAMCIRDMMQGNSKLADIGRVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEAILNSSFDWNGVRKPFVVATENDSLNGVAMLMGHQLTGTAQVFADVRTYWSPEAIERVTGHKLDGLAEHGIIHLINSGSAALDGSCKQRDSEGNPTMKPHWEISQQEADACLAATEWCPAIHEYFRGGGYSSRFLTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVELPKDVHDILNKRTNSTWPTTWFAPRLTGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLASMLRIPVCMHNVEETKVYRPSAWAAHGMDIEGQDYRACQNYGPLYKR", "output": "Converts the aldose L-fucose into the corresponding ketose L-fuculose."}]}
+{"id": "function_test_2129", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPEGPEIRRAADNLEAAIKGKPLTDVWFAFPQLKSYQSRLIGQHVTHVETRGKALLTHFSNDLTLYSHNQLYGVWRVVDTGEEPQTTRVLRVKLQTADKTILLYSASDIEMLTPEQLTTHPFLQRVGPDVLDPNLTPEVVKERLLSPRFRNRQFAGLLLDQAFLAGLGNYLRVEILWQVGLTGNHKAKDLNAAQLDALAHALLDIPRLSYATRGQVDENKYHGALFRFKVFHRDGEPCERCGGIIEKTTLSSRPFYWCPGCQH", "output": "Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates."}]}
+{"id": "function_test_2130", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MFPMVTEFMNYGQQTVRAARYIGQGFTITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPETKT", "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_2131", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIPLLFILFYFTNCIEWHKFETSEEIISTYLIDDVLYTGVNGAVYTFSNNELNKTGLTNNNNYITTSIKVEDTLVCGTNNGNPKCWKIDGSEDPKYRGRGYAPYQNSKVTIISHNECVLSDINISKEGIKRWRRFDGPCGYDLYTADNVIPKDGVRGAFVDKDGTYDKVYILFTDTIDTKRIVKIPYIAQMCLNDEGGPSSLSSHRWSTFLKVELECDIDGRSYRQIIHSKAIKTDNDTILYVFFDSPYSKSALCTYSMNAIKHSFSTSKLGGYTKQLPSPAPGICLPAGKVVPHTTFDIIEQYNELDDIIKPLSQPIFEGPSGVKWFDIKEKENEHREYRIYFIKENTIYSFDTKSKQTRSAQVDARLFSVMVTSKPLFIADIGIGVGIPRMKKILKM", "output": "Acts as a semaphorin-like protein and binds to host plexin C1 receptor. May alter the movement of plexin C1-expressing cells including dendritic cells, monocytes, or granulocytes in the proximity of infected cells. May also regulate host cell cytoskeleton of neighboring cells to improve viral infection."}]}
+{"id": "function_test_2132", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDIVLEICDYYLFDKVYADVFPKDGPVHEYLKPAIQSFSEINFPKLQNWDSFDTNSTLISSNNFNISNVNPATIPGYLLSKIASYQDKSEIYGLAPKFFPATEFIDTSFLSRSNIFREVLSLFIITTLFGWLLYFIVAYLSYVFVFDKKIFNHPRYLKNQMSLEIKRATSAIPVMVLLTIPFFLLELHGYSFLYEEINESTGGYKAILWQIPKFILFTDCGIYFLHRWLHWPSVYKALHKPHHKWIVCTPFASHAFHPVDGFFQSLPYHLYPLLFPLHKVLYLLLFTFVNFWTVMIHDGSYWSNDPVVNGTACHTVHHLYFNYNYGQFTTLWDRLGNSYRRPDDSLFVKDQKKEEEKKIWKEQTRQMEEIRGEVEGKVDDREYIDQ", "output": "Catalyzes the introduction of a C-5 double bond in the B ring of ergosterol. May contribute to the regulation of ergosterol biosynthesis."}]}
+{"id": "function_test_2133", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNIIDELSWRGLINQSTDLEALREEASTPITLYCGFDPTGPSLHAGHLVPLLMLRRFQQAGHNPIVLAGGATGMIGDPRDVGERTMNSADTVSDWAERISGQLSRFVDFDGEHAARLVNNAEWTNEMSVVTFLRDVGKHFSLNTMLARDTVKRRLESDGISYTEFSYMLLQANDYVELNKRFGCTLQVGGGDQWGNIVSGVDLNRRVNGTSVHAVTVPLVTDSDGKKFGKSTGGGSLWLDPEMTSPYAWYQYFINASDADVIRYLRWFTFLTQEELAELEVEVAERPFKREAQRRLAREMTNLVHGTEATEAVELAAQALFGRAELRDLDEKTLAASVSETAVAEIKAGEPRTIIDLLVASGLADSKGAAKRAVKEGGAYVNNERIESDDWEPFAEDLLHGSWLVLRRGKKNFAGVQILG", "output": "Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr)."}]}
+{"id": "function_test_2134", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKSIEVHTDGSCLGNPGPGGWAALLRYNGREKELAGGEANSTNNRMELMAAIMALETLTEPCQILLHTDSQYVRQGITEWMPGWVRRGWKTSGGDPVKNRELWERLHAATQRHSIEWRWVKGHNGDPDNERVDVLARNQAIAQRGGLATS", "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."}]}
+{"id": "function_test_2135", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTEVVQNVAQTHITVENLNLWYGEKQALKNVSLKIPRNSVTALIGPSGCGKSTFIRCLNRMNDLVKNCRIEGKVLIENEDIYGTDVDVVELRKQVGMVFQKPNPFPMSIYDNVAYGPRIHGVNKKDIDGVVRNALRSAALFEETSDRLKSPALSLSGGQQQRLCIARTLAVKPRIILFDEPTSALDPISTARIEDLIMNLKKDYTIVIVTHNMQQAARISDYTGFFLMGELVEFGQTRQIFHSPREKSTEDYITGRFG", "output": "Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system."}]}
+{"id": "function_test_2136", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MARAKLKNSPSESNSHVKTVPPATTEDVRGVSPLLPARRMGSLGSDVGQRPHAEDFSMDSSFSQVQVEFYVNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLTCLLYIVRVLLDNPEEGIGCWECEKQNYTLFNQSTKINWSHIFWVDRKLPLWAVQVSIALISFLETMLLIYLSYKGNIWEQIFRISFILEMINTVPFIITIFWPPLRNLFIPVFLNCWLAKYALENMINDLHRAIQRTQSAMFNQVLILICTLLCLVFTGTCGIQHLERAGEKLSLFKSFYFCIVTFSTVGYGDVTPKIWPSQLLVVIMICVALVVLPLQFEELVYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDIQVRRVLQIPLWSQRVIYLQGSALKDQDLMRAKMDNGEACFILSSRNEVDRTAADHQTILRAWAVKDFAPNCPLYVQILKPENKFHVKFADHVVCEEECKYAMLALNCVCPATSTLITLLVHTSRGQEGQESPEQWQRMYGRCSGNEVYHIRMGDSKFFMEYEGKSFTYAAFHAHKKYGVCLIGIRREENKSILLNPGPRHIMAASDTCFYINITKEENSAFIFKQAEKQKKKGFAGRGTYDGPSRLPVHSIIASMGTVAMDLQNTECRPTNSSKLALPAENGSGNRRPSIAPVLELADTSSLLPCDLLSDQSEDEMTQSDEEGSAVVEYVKGYPPNSPYIGSSPTLCHLLPEKAPFCCLRLDKGCKHNSFEDAKAYGFKNKLIIVSAETAGNGLYNFIVPLRAYYRSRKELNPIVLLLDNKPEHHFLEAICCFPMVYYMEGTIDNLDSLLQCGIIYADNLVVVDKESTMSAEEDYMADAKTIVNVQTMFRLFPSLSIITELTHPSNMRFMQFRAKDSYSLALSKLEKKERENGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMITITRLLLGLDTTPGSGYLCAMKITEDDLWIRTYGRLFQKLCSSSAEIPIGIYRTESHMFATSEPHDIRAQSQISINVEDCEDTKDVKEHWGIKTGHHRNSCSSDQSEHPLLRRKSMQWARRLSRKGNKHSGKTAEWISQQRLSLYRRSERQELSELVKNRMKHLGLPTTGYDEMNDHQNTLSYVLINPPPDTRLELNDIVYLIRSDPLAHVANDGHSRKSSCSNKLGPCNPETRDETQL", "output": "Generates outwardly rectifying currents that are suppressed by elevation of intracellular calcium."}]}
+{"id": "function_test_2137", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRIVVKVGTSTLTHENGKLNLEIMEKLVRQIANLSNKGEEVILVTSGAIGAGMGKLNLTEKPKNLPQKQALAAIGQGLLIEIYEKFFNEYGKITAQLLLTREDFSDRKRYLNMSYTLSNLLKWGVIPVINENDTVAVEEIKIGDNDTLAALVASLVEADLLIILTDIDGLFDKDPRIYKDAKVIEVVEEFSDDLFKIAGGAGTKRGTGGMYTKIQAAKICYNSGVKMVIANGKIDNVLNRIAAGEKIGTTFLPMKNPISSRKIWIAFNAKVNGFLFVDEGAAKALVKHGKSLLPSGIVKTEGQYDVGDCVAVVDHQGREIARGLVNYSSEEVEKIKGCKTHDIESILGYKYYDEVIHRDNLVVLERGEKYGG", "output": "Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate."}]}
+{"id": "function_test_2138", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTNLRKTHPLMKIINSSFIDLPAPSNISSWWNFGSLLGICLIVQILTGLFLAMHYTSDTMTAFSSVTHICRDVNYGWLIRYLHANGASMFFICLFLHVGRGLYYGSYMFLETWNIGVLLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGSDLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAGVHLLFLHETGSNNPSGLCSDADKIPFHPYYTIKDILGVLLLILVLTSLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILVLAVVPFLHTSKQRSMMFRPFSQCLFWILVADLLTLTWIGGQPVEHPFIIIGQLASILYFLLILVLMPITSLFENNLLKW", "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."}]}
+{"id": "function_test_2139", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MELKFSAEVELTLSREVDPAEIEPTVEEFVKEANEDLLQRGVPTGKEGAKIESYRVLEDTIEMEITGTRYLRPHEAAMRVRKRLAERLGRKHRVGVRDLKIPRYEVVLRFDREVTRDDVGYVPVADDVVVEDGTVRLTFQDVDEEMLRRHVIDRVIRLVAWAVEERSELVERVTKVEPGTVVDESGPREIRFDGDVTEEARRRGWVKEFPGRGQWIYTPPMAALFEVLRDFLLERVTRKLGFEPALFPKLIPLETMFRMRYLHGLPDGMYYVCPPKRDPELFDDFKRELYVWGELNERTLGSLKEKLRDPGYVLAPAQCEPFYELLRDEVVDPERLPIKLYDCSGWTYRWEGGAAKGLERVNEFQRIEHVWIAEPEEAERIREELLEATKRVAEELELEWKVVVSDDPFYLEGRLLEDRDIELPDVPSYEFEVYLPFKGERSSEEAWISVGSFNVHGEHFVDGFNVKEKSGRTLFTGCAGLGVTRWVVGLLAQHGFEPEEWPEPILERIDEKFGGLPEVPKTLTWPE", "output": "Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)."}]}
+{"id": "function_test_2140", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGKVHRPRRGSLGFSPRKRAKSIVPRIRSWPKETEVRMLGFAGYKAGMTHILMIDDEPGLTNGKEIFMPVTIIETPPLRVFGIRAYRMGYLGLETATEVIVPDFPLDNYPAKERKGKPKPKMTFYKLLERRIATLPKNYTQEMFEQKLGQLEDMIKEGEIVDVRAIVATQPWVIKLKKKPEVMEYAIGGTSVEEKFNYIKEKLGKELRVGEVLKEGELLDVIAVTKGKGTQGPVKRWGIKLRAHKDSKGRRKVGSIGPWHPARVMWTVPMAGQMGFHHRTELNKRLIAIGENGKLKLDENTEIEITPKGGFPHYGIVRSDFMMIAGSVPGAIKRIIRVRPAIRPPKKKPPVQRPQITYVSVESKQ", "output": "One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit."}]}
+{"id": "function_test_2141", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPVDNDGFSAVEAIAPGVIDRQSVDQPVQTGYKAVDSMIPIGRGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNADYVEAFTKGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLESNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELAKIGSFEAALLAYVDRDHAPLMQEINQSGGYNDEIEGKLKGILDSFKATQSW", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit."}]}
+{"id": "function_test_2142", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKTKLILLYGGKSAEHEVSLQTAFSVINALDLEKFEAAPIYITNEGEWIQGPLLSGKLDFVEQLRFSATDTIKLATTESEKSEGEAISPAVLEADGQETVVFPLLHGPNGEDGTVQGLFEVLNIPYVGNGVLASSAAMDKIVMKKIFADAGIPQVPAVAVRLIDWKNYQEEMVAEMEEVLTYPVFVKPANLGSSVGISKATNKKELVDAMTEAFLYDRRVVVEQGVVAREIEMGVLGNDTPVCSVPGEILPEGAVATFYDYKAKYQDNNTALIIPTEVDPEILEQMKEYAIQAFLGLDASGLVRADFFLTEDNQLFLNEVNTMPGFTPYSMYPLLWQETGLPYGALIERLVDLAKERHAAKNALKYKLED", "output": "Cell wall formation."}]}
+{"id": "function_test_2143", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MASDSSFPGASSNVAEYSVSEISGALKRTVEDTFGHVRVRGEISGYRGPHSSGHAYFALKDDRARLEAVIWRGSMSRLRFRPEEGMEVIATGKLTTYPGSSKYQIVIEQMEPAGAGALMALLEERKQRLAAEGLFDPALKQLLPFMPRVIGVVTSPTGAVIRDIIHRISDRYPLRVIVWPVRVQGDTCGPEVATAVNGFNTLPDDGPIPRPDVLIVARGGGSLEDLWGFNDEIVVRAVAASHIPVISAVGHETDWTLIDLAADMRAPTPTGAAEMAVPVKADLQASLASQSARLSSAMSRFFDQKRQAHRAAARAMPSADQLLALPRRRFDEAASRLTRALFVNTQKKRVHFDGHARQLSPRLLQRRLVELERGVTMLGQRLPRALEAFLRERRTAFTHRANRLSPEPILRRTRLTGSTLEQLDRRRDQAVRLLIERVKRRSQELDRLMRTLSYESVLERGFAVVFDAQGKPVKQAAAVSPGDALSVRFRDGDVGVVARAGLTIPDPTKGQ", "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."}]}
+{"id": "function_test_2144", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKFELDTTDGRARRGRLVFDRGVVETPAFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSMEMSLRWAKRSRDRFDSLGNKNALFGIIQGSVYEDLRDISVKGLVEIGFDGYAVGGLAVGEPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKHKSDTSPLDAECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHNLRYYQRLMAGLRKAIEEGKLESFVTEFYQRQGRPVPPLNVD", "output": "Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)."}]}
+{"id": "function_test_2145", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKFPILIINFKAYYEASGRRAVHIAKAAERVAKELGVNIAVAPNHLELALVAQSVEIPVYAQGADVESPGAHTAHVAVDNIKEAGASGLILNHSEAPLRLNEIAKLTARAKAAGLDVVICAPDPRTSLAAAALSPHAVAVEPPELIGTGRAVSKYKPETVVETVQLVGRHFPDVAVITGAGIESGEDVEAALKLGTRGVLLASAAVKAKDPYLKILELAKPLAAGPP", "output": "Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)."}]}
+{"id": "function_test_2146", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MVRYRMRSPSESPHQGPGQDHESEEQGQGQELNPERVEDYGRTHRGHHRHRRCSRKRLHRIHKRRRSCRRRRRHSCCHRRRHRRGCRRSRRRRRCRCRKCRRQCH", "output": "Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex."}]}
+{"id": "function_test_2147", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLDNFIAHQATKEFSVSEISNKIKELLENNFGYIKVKGEISGLKIANSGHAYFNLKENTAILACTCWRPILAKITFPLNDGMEVVISGKLSSYAGNSRYQLSVDNLQPTGLGAMLQILNERKAKLEKEGLFNKIRIPIPFLPDKIGVITSITGAVIKDIIHRIRERFPTRIIIWPVSVQGENSGNEIAEAIEGFNNLEEVNKPRVIIVARGGGSIEDLWSFNDEILVRAAYNSKIPIISAVGHEVDYTLIDLAADKRAPTPTAAAEFAVPVRSILNNTLQSYEKILLNNTSRLIKYHEQNIVNYNKIHRYLSHYINNRQQLLDETGFNLLDALPCFIELQETKIKSFSKERVNPAKIINYKTLELTHQTAYLSKSANNTLKNFEYKLELNSTLLASLDYHNVLKRGFAIVKGETGNFLSSKMTAANEKIFNIKFSDGEIKVVRA", "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."}]}
+{"id": "function_test_2148", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLILPIVKGEYKKDYNLKHLTWFKVGGNAEIFFKPLDSEDLKSFLIQNKQKLPIKTFGAGSNIIIRDGGIEGVVIKLGQNFSNIEFVDNHLIVGSSCLNYNLAKFCQANAISGFEFLVGIPGTIGGGVAMNAGAYGSEFKDIVVQIEAIDFAGNFLTFTNEEIGFKYRSNNLPKNLIILKAVFKINKGDSENILLRMNEIKNARSSTQPIKERTGGSTFANPEGRKSWELIDKAGLRGYRIGGASMSEFHCNFMINNGDATAKDLEDLGDFVRQKVCEDSGVKLEWEIKRIGRHP", "output": "Cell wall formation."}]}
+{"id": "function_test_2149", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDRAFCGNFYYNGKFDYLEVTVKDGVIESIKKDAGNIARSYLPGAVLPAATDIHVHFRTPGETDKEDFSTGSLSAIFGGTTLVMDMPNNIIPIKDYNAFSDKLGVINGTSYSDFALYSMETGSNSLIVDSRSIGLKVYLGGSTNAAGTMAIPDQEAEMINEKGFTVIFHGELEECLRKHQSETKNLREHNLSRPIECELAAAGYVGSLNLKSKIMAHVSSPEVSGDFLREVTPHHLLLNDEMPLGSIGKVNPPLRDRNTQERLLYAYISGQFDILSSDHAPHTEKDKAEFEYAKSGIIGVETRIPLMLALVKKKILFLDVLYKTGIERPPSIFGIRKGKIEVGYDADFMCVDFTNEKKVNEDRLHSKLPRSPFNGMDAIFPSHVVMRGEVVIDNYEEISDPLGRFVPKGYYDQKL", "output": "Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate."}]}
+{"id": "function_test_2150", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKERAVLEYLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDLRVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQGQLAQESQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGVEIVIGAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLESSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILLGDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLLRTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAPLETLFASRKQKAEKLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVLEQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYAIGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSARKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSLVAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPTSPSSKTLAKDTLQALYPAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLHPDARSHGNFLHRIFERALQLPNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIETIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPHFFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKYQGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYTENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREELNR", "output": "Involved in DNA double-strand break repair. Is not involved in recombination during natural competence or in plasmid establishment.; "}]}
+{"id": "function_test_2151", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MFELLGTTLPSRLLLGTAQYPSPAILADAVKASGTSVVTVSLRREMAGGRAGEKFWSLIRSLGVRILPNTAGCHSVKEAVTTAKMARDVFGTSWIKLEVIGSHDTLQPDVFGLVEGARILCEDGFSVFPYTTDDLVVAERLLEAGCRVLMPWCAPIGSALGPVNMTALRSMRGHFPDVPLIVDAGLGRPSHAATVMELGFDAVLLNTAVARAADPVGMARAFGKAVDAGREAFSSGLLEPREVAVPSTPIFGRAVFS", "output": "Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S."}]}
+{"id": "function_test_2152", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MANVVVVGSQWGDEGKGKIVDWLSERADVVVRFQGGHNAGHTLVVDGKVYKLSLLPSGVVRQGKLSIIGNGVVFDPHAFVAEVAKLKAQGVEVTPDRLKIAENTALILSLHRELDGFREDAASNSGTKIGTTRRGIGPAYEDKVGRRAVRVMDLADLETLPLKVDRLLTHHNALRRGLGHGEVTHDAIMAELTSVADEILPYMDRVWKILDDKRRAGERILFEGAQGTLLDIDHGTYPFVTSSNTVAGQAAAGSGVGPGAIGYVLGITKAYTTRVGEGPFPTEQKNEIGEFLGTRGHEFGVVTGRKRRCGWFDAVLVRQAVAVNGIKGIALTKLDVLDGLDEIKVCTGYRLDGEMIDYLPASQGAQARVEPVYETLEGWKGTTAGARSWNDLPAQAVKYVRYIEELIGAPVALLSTSPERDDTILVTDPFQD", "output": "Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP."}]}
+{"id": "function_test_2153", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKVIKTLSIINFFIFVTFNIKNESKYSNTFINNAYNMSIRRSMEESNPPTGASGRAGAGASGRAGAGASGRAGAGAGAVASAGSGDGAVASAGNGANPGADAKRSTSTPATTTTTTTTNDAEASTSTSSENPNHNNAKTNPKGKEVQEPNKANTETQNNSNVQQDSQTKSNVPPTQDADTKSPTAQPEQAENSAPTAEQTESPELQSAPENKGTGQHGHMHGSRNNHPQNTSDSQKECTDGNKENCGAATSLLNNSSNIASINKFVVLISATLVLSFAIFI", "output": "May play a role in the merozoite attachment to the erythrocyte."}]}
+{"id": "function_test_2154", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MMSRLNSVVIKLWLTIILIVTTVLILLSIALITFMQYYFTQETENAIREDARRISSLVEQSHNKEEAIKYSQTLIENPGGLMIINNKHRQSTASLSNIKKQMLNEVVNNDHFDDVFDKGKSVTRNVTIKEKGSSQTYILLGYPTKAQKNSHSKYSGVFIYKDLKSIEDTNNAITIITIITAVIFLTITTVFAFFLSSRITKPLRRLRDQATRVSEGDYSYKPSVTTKDEIGQLSQAFNQMSTEIEEHVDALSTSKNIRDSLINSMVEGVLGINESRQIILSNKMANDIMDNIDEDAKAFLLRQIEDTFKSKQTEMRDLEMNARFFVVTTSYIDKIEQGGKSGVVVTVRDMTNEHNLDQMKKDFIANVSHELRTPISLLQGYTESIVDGIVTEPDEIKESLAVVLDESKRLNRLVNELLNVARMDAEGLSVNKEVQPIAALLDKMKIKYRQQADDLGLNMTFNYCKKRVWSYDMDRMDQVLTNLIDNASRYTKPGDEIAITCDENESEDILYIKDTGTGIAPEHLQQVFDRFYKVDAARTRGKQGTGLGLFICKMIIEEHGGSIDVKSELGKGTTFIIKLPKPE", "output": "Member of the two-component regulatory system SrrA/SrrB, which is involved in the global regulation of staphylococcal virulence factors in response to environmental oxygen levels as well as biofilm formation. Also plays an essential role in host-derived nitric oxide resistance by regulating hmp/flavohemoglobin, an enzyme that detoxifies nitric oxide by converting it to nitrate. Functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to SrrA. In turn, SrrA binds to the upstream promoter regions of the target genes to positively and negatively regulate their expression."}]}
+{"id": "function_test_2155", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKRMKLRTNAGPLQGTIQVPGDKSISHRAVILGAVAKGETRVKGLLKGEDVLSTIQAFRNLGVRIEEKDDQLVIEGQGFQGLNAPCQTLNMGNSGTSMRLIAGLLAGQPFSVKMIGDESLSKRPMDRIVYPLKQMGVEISGETDRQFPPLQLQGNRNLQPITYTLPISSAQVKSAILLAALQAKGTTQVVEKEITRNHTEEMIQQFGGRLIVDGKRITLVGPQQLTAQEITVPGDISSAAFWLVAGLIIPGSELLLKNVGVNPTRTGILEVVEKMGAQIVYEDMNKKEQVTSIRVVYSNMKGTIISGGLIPRLIDELPIIALLATQAQGTTCIKDAQELRVKETDRIQVVTDILNSMGANIKATADGMIIKGPTVLYGANTSTYGDHRIGMMTAIAALLVKQGQVHLDKEEAIMTSYPTFFKDLERLCHD", "output": "Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate."}]}
+{"id": "function_test_2156", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVTVDEVRKAQRAEGPATILAIGTATPPNCVDQSTYPDYYFRITKSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKENPSMCEYMAPSLDARQDMVVVEIPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIVGSDPLPDIERPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLNEAFKPLDITDWNSLFWIAHPGGPAILDQVEAKLGLKPEKLEATRNILSEYGNMSSACVLFILDEVRRKSVANGHKTTGEGLEWGVLFGFGPGLTVETVVLHSVAAST", "output": "Polyketide synthase producing naringenin chalcone and slightly p-coumaryltriacetic acid lactone (CTAL). Can use p-coumaryl-CoA as substrate."}]}
+{"id": "function_test_2157", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MANRNLEKMASIDAQLRQLAPSKVSEDDKLIEYDALLLDRFLDILQNLHGEDLKETVQEVYELSAEYEGKHDPKKLEELGNVITSLDAGDSIVVAKSFSHMLNLANLAEEVQISRRRRNKLKKGDFADENNATTESDIEETLKKLVFELKKSPQEVFDALKNQTVDLVLTAHPTQSVRRSLLQKHARIRNCLSKLYAKDITPDDKQELDEALQREIQAAFRTDEIRRTPPTPQDEMRAGMSYFHETIWNGVPSFLRRVDTALNNIGIKERVPYNAPLIQFSSWMGGDRDGNPRVTPEVTRDVCLLARMMAANMYYSQIEDLMFELSMWRCNDELRVHADEVHRSSNKDEVAKHYIEFWKKVPTNEPYRVVLGEVRDRLYQTRERSRHLLSNGYSDIPEENTFTSVEEFLQPLELCYRSLCACGDRAIADGSLLDFLRQVSTFGLSIVRLDIRQESDRHTDVLDAITKHLEIGSYQEWSEEKRQEWLLSELSGKRPLFGPDLPQTEEIRDVLDTFHVIAELPPDNFGAYIISMATAPSDVLAVELLQRECHVKHPLRVVPLFEKLADLEAAPAALARLFSVDWYKNRIDGKQEVMIGYSDSGKDAGRFSAAWQLYKAQEELVKVAKKFGIKLTMFHGRGGTVGRGGGPTHLAILSQPPDTIHGSLRVTVQGEVIEQCFGEQHLCFRTLQRFTAATLEHGMNPPISPKPEWRAMMDQMAVIATEEYRSIVFKEPRFVEYFRLATPELEYGRMNIGSRPAKRRPSGGIETLRAIPWIFAWTQTRFHLPVWLGFGAAFKQVLDKNAKKNLSMLQEMYNQWPFFRVTLDLVEMVFAKGDPKIGALNDRLLVSKDLWPFGDQLRNKYEETKKLLLQVAGHKEILEGDPYLKQRLRLRHSPITTLNVFQAYTLKRIRDPNYKVKARPRISKESAEASKSADELIKLNPTSEYAPGLEDTLILTMKGIAAGMQNTG", "output": "Through the carboxylation of phosphoenolpyruvate (PEP) it forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle."}]}
+{"id": "function_test_2158", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTNIRKSHPLIKIINHSFIDLPTPSNISSWWNFGSLLGICLILQILTGLFLAMHYTPDTTTAFSSVAHICRDVNYGWIIRYTHANGASMFFICLFIHVGRGLYYGSYTFLETWNIGTIFLLTLMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVEWIWGGFSVDKATLTRFFAFHFILPFIILALAITHLLFLHETGSNNPSGIPSNMDKIPFHPYYTIKDILGALLLILALLTLVLFSPDLLGDPDNYTPANPLSTPPHIKPEWYFLFAYAILRSIPNKLGGVLALAFSILILLIVPSLHTSKQRSMMFRPLSQCVFWLLVADLLTLTWIGGQPVEHPFIIIGQLASILYFSLILVLMPLAGIIENNLLKW", "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."}]}
+{"id": "function_test_2159", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTNIRKTHPLLKIINSSFVDLPAPSSLSAWWNFGSLLGVCLAVQILTGLFLAMHYTSDTATTFNSVTHICRDVNYGWLIRYLHANGASMFFICLYLHVGRGLYYGSYTYSETWNVGILLLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTDLVQWIWGGFSVDKATLTRFFAFHFLLPFIVTALVMVHLLFLHETGSNNPTGIPSDSDMIPFHPYYTIKDILGFLIMLTALSALVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVMSILILAIVPVLHTSKQRSMMFRPLSQCLFWLLVAILFTLTWIGGQPVERPFIIIGQTASVLYFLIILILMPVTSLMENYLLKW", "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."}]}
+{"id": "function_test_2160", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLKITLIAACAENLCIGAGNAMPWHIPEDFAFFKAYTLGKPVIMGRKTWESLPVKPLPGRRNIVISRQADYCAAGAETAASLEAALALCAGAEEAVIMGGAQIYGQAMPLATDLRITEVDLSVEGDAFFPAIDRTHWKEAERTERRVSSKGTRYAFVHYLRY", "output": "Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)."}]}
+{"id": "function_test_2161", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTKKVVTITLNPALDLTGSVNQLNVGSVSLVGQSSLHAAGKGVNVAKVLSELGAQVTVTGFLGRDNQELFCQLFEQLGVQDAFIRIAGATRINVKLVEQSGAVSDINFPGIQVTEADIEAFEATLQRLAQDHDYFVLAGSLPQGISPQRCAGWIAQLRSMNKKVLFDSSRDALLAGLDAKPWLIKPNDEELSQWCGRELTTLTDCQQAAAELAQKQIENIVISMGAEGVMWLHENQWLHAKPPKMQVVSTVGAGDTLVAGLCWGHMQRMEKESLLRFATALSALAVTQVGVGLGDREQLNTLQQQIQVSALYPTMGA", "output": "Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate."}]}
+{"id": "function_test_2162", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRKFTILLMLLLASSAQAARIKDVAQVAGVRNNQLVGYGLVTGLPGTGESTPFTDQSFNAMLQSFGIQLPPGTKPKTKNVAAVIVTADLPAFSKQGQTIDITVSSIGSAKSLRGGTLMQTFLKGLDGQVYAVAQGNLVVSGFSATGADGSKIVGNNPTVGMISSGAIVEREVPNPFGRGDYITFNLFESDFTTAQRLADAVNQFLGPQMASAVDAASIKVRAPRDLSQRVAFLSAIENLEFNPADSAAKIIVNSRTGTIVVGQNVRLKPAAVTHGGMTVAIKENLNVSQPNALGGGQTVVVPNTEIEVTEKQGKMFKLEPGVTLDDLVRAVNEVGAAPSDLMAILQALKQAGAIEGQLIII", "output": "Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation."}]}
+{"id": "function_test_2163", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSPIFDALVPMVVEQTSRGERSYDIYSRLLKERVIFLTGQVEDHMANLVVAQLLFLESENPDKDIFLYINSPGGSVTAGMSIYDTMQFIKPNVSTVCMGQACSMGAFLLAGGAPGKRYVLPNSRVMIHQPLGGFQGQASDIQIHAQEILTIKNKLNRLLAEHTGQPIEVIERDTDRDNFMSADQAVEYGLVDAVLKHRGE", "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins."}]}
+{"id": "function_test_2164", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQIQLGANLKPYHTFGIEQLAAQLVVAESIDDLKALYCSAEWASLPKLIIGKGSNMLFTCHYTGMIVVNRLNGIEHQQDDDYHRLHVAGGEDWPSLVSWCVEQGIGGLENLALIPGCAGSAPIQNIGAYGVEFKDVCDYVEYLCLETGTVKRLTMEECQFGYRDSIFKHQLYQKAVVTAVGLKFAKAWQPIIQYGPLKDLSSDCAIHDVYQRVCATRMEKLPDPAVMGNAGSFFKNPVISQQAFARLQIEHPDVVAYPAEQGVKVAAGWLIDQAGLKGHQIGGAKVHPKQALVIVNTGDASAQDVLMLAADIQQRVFNCYGIELEHEVRFIGESEETNLKQWMSEQA", "output": "Cell wall formation."}]}
+{"id": "function_test_2165", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSSERTFLPNGNYKIKSLFSDSLYLTYSSGSLSFLNTSSLDNQKWKLEYISSSNGFRFSNVAEPNKYLAYNDYGFIYLSSSSNNSLWNPIKIAINSYIICTLSIVNVTDYAWTIYDNNNNITDQPILNLPNFDINNSNQILKLEKL", "output": "The hemagglutinin (HA) component of the progenitor toxin protects the structural integrity of the neurotoxin; may increase internalization of the neurotoxin into the bloodstream of the host (By similarity). Involved in binding to the small intestine through interactions with glycolipids and glycoproteins containing sialic acid moieties (Probable). The hemagglutinin complex composed of HA-70, HA-33 and HA-17 agglutinates erythrocytes, whereas the individual compenents do not . Erythrocyte agglutination also occurs with the entire toxin complex ."}]}
+{"id": "function_test_2166", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKRNDPCWCGSQKKWKHCHYPTKPERPSDNLRQLYASRYDIIIKTPDQIEKIRKACQVTARILDALCKAAKEGVTTNELDQLSCNLHKQYNAIPAPLNYGQPPFPKTICTSLNEVICHGIPNDTPLQNGDIMNIDVSCIVDGFYGDCSRMVMIGEVPEIKKKVCEASLEALNAAIAILEPNLPLYEIGEVIENCAARYGFSVVDQFVGHGVGVRFHENPYVAHHRNSCKIPLAPGMTFTIEPMINVGKKEGFIDPTNHWEARTCDHQPSAQWEHTVLITDSGYEILTLLDN", "output": "Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed."}]}
+{"id": "function_test_2167", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKFLKRGVALALLAAFALTTQPAQAYEKDKTYKITILHTNDHHGHFWRSEYGEYGLAAQKTLVDSIRKEVAQEGGGVLLLSGGDINTGVPESDLQDAEPDFRGMNLIGYDAMAVGNHEFDNPLTVLRQQEKWAKFPFLSANIYQKSTGERLFKPWAIFTRQDIKIAVIGLTTDDTAKIGNPEYFTDIEFRKPAEEAKVVIQELNMNEKPDVIIATTHMGHYDNGDHGSNAPGDVEMARSLPAGSLAMIVGGHSQDPVCMASENKKQVNYVPGTPCAPDKQNGIWIVQAHEWGKYVGRADFEFRNGEMKMVNYQLIPVNLKKKVTWDNGKSERVLYTPEIAENPQMLLLLTPFQNKGKVQLEVKIGSVNGLLEGDRSKVRFVQTNMGRVILAAQIARTGADFGVMSGGGIRDSIEAGDITYKSVLKVQPFGNIVVYADMSGKEVVDYLTRVAQMKPDSGAYPQLANVSFVAKEGKLTDLKIKGEPVDPAKTYRMATLSFNATGGDGYPRIDNKPGYVNTGFIDAEVLKEFIQQNSPLDAAAFTPKGEVSWL", "output": "Degradation of external UDP-glucose to uridine monophosphate and glucose-1-phosphate, which can then be used by the cell."}]}
+{"id": "function_test_2168", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQVILLEPSRLGKTGEVVSVKDGYARNWLIPQGLAVSATRTNMKTLEAQLRSIEKRQAQEKAVAEDLASRLNGVAVELSVRAGEGKIYGAVTHQDVANSLDQLGFDVDRRKIDMPKTVKEVGEYDIAYRAHPEVTIPMKLVVHAAK", "output": "Binds to the 23S rRNA and protein L31."}]}
+{"id": "function_test_2169", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MREVLSIHIGQAGIQVGNACWELYCLEHGINPDGSIIQDFNKKKNDDAFSTFFSETSTGKRVPRCVFLDLESGVIDEVKNGRYKNLYHPEQLICGNEDAANNYARGHYTIGKEIIEIALDRIRKLVENCSGLQGFLIFNSVGGGTGSGLGSLLLERLSLDYGKKSKLGFTVYPSPQVSTAVVEPYNSVLATHSLLEHTDVAVVLDNEAIYEICQRSLNIERPTYTNLNRLIAQVISSITASLRFDGALNVDITEFQTNLVPYPRIHFMLSSLAPVISLEMANHEQYSTAEITNAAFEPNSMMAKCDPRRGKYMACCLMFRGDVAPKDVNGSVAAIKTKKTIQFVDWCPTGFKCGINYQPPTVVPDGDLAKVDRAVCMISNSTAISEVFSRINKKFDLMYSKRAFVHWYVGEGMEEGEFNEAREDMAALEKDYEEVGSESQDLISNSFF", "output": "Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin."}]}
+{"id": "function_test_2170", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTNIRKSHPLFKIINHSFIDLPAPSNISSWWNFGSLLGVCLILQIITGLFLAMHYTADTTTAFSSVTHICRDVNYGWLIRYLHANGASMFFVCLFLHVGRGIYYGSYTFMETWNIGIILLFAVMATAFMGYVLPWGQMSFWGATVITNLLSAIPYIGTTLVEWIWGGFSVDKATLTRFFAFHFILPFIIAALAMVHLLFLHETGSNNPSGLNSDGDKIPFHPYYTIKDILGVLLLILILVSLVLFSPDLLGDPDNYTPANPLNTPPHIKPEWYFLFAYAILRSIPNKLGGVLALVLSILILALLPLLHTSKQRSLMFRPITQILFWILVADLFTLTWIGGQPVEYPFIIIGQLASILYFSIILIFMPISGIIEDKILKLY", "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."}]}
+{"id": "function_test_2171", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSCWTLVQQDFLEAPSVDALKTSLESKNDYVKISAMKTILRVVINGDSLPSILMHVIRFVMPSRNKELKKLLYYYWEVCPKYNNDGTMKQEMILACNSFRNDLQHPNEFIRGATLRFLCKLKEPELLDPLIPTVRQCLEHRHAYVRKNAILAVFSIYQVSNHLIPDAASLAEDFLAAESEGTCKRNALIVLFTIDPEKAKAWLLANFEQIPSLNASSLLVIIEFIRKVVLTKADGLEKLRFQSLLVSLTATNNSSVVFEAATSVINVFPDAESLKLAASRLLALADREADNNAKLIMLDRISQLAARDKSILEDLITDVIPFLSSSDFDVCEKAISIIMGLVSSRNVEDILNHFQKELTKSNGETEKDDGRRRALTKAIHSCAINFPHTAATAIQYLLSHISDFQSKSASSVLSFIKEVMEKFPDLRSSNITKLLLSLKELRAGKIFRGVIWIAGEYCLTEDDIRVAWKSIRASLGEVPILASEEQLLKDVSNVPEDDLLIDISAPASTSRKVLPDGTYATESAVTSEALSAARLEAVKASKKPPLRTQILSGDYYLAAVLASALTKLVMRFARLSFDKERLNALKAEACLIMTSIIRVGQSKFVKYTIDDDSVERIMNCIRAIYSFEELPEFQTVFLDDMRKAFSSLVAQSDKRQKEADLLVNGSDAVQADELLNIRQFQRVIEEKQDLNFESDIIQATNDGMVVEDLASKLDHIVQLAGFTDPVYCEAYVKIQQFDIILDILLVNRTDTTLQNLSVDLATLGDLKVVERPPPMNLGPHAFKSVQATVKVSSTESAVIFGNIVYGGKASDEDKIVVLNGIPVNIIDYIKPAFIPESQFRSMWTEFEWENKVDISSNEDISLYDFLHKIMKKTNMNCLTPDASLRGDCGFLSANLYACSIFGEDALMSLSVEKSVSGPISGHVRIRSKTQGIALSLGAFV", "output": "The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity)."}]}
+{"id": "function_test_2172", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDGKAPAAFVEPGEFNEVMKRLDKIDEKIEFVNSEVAQKIGKKVGRDIGILYGGFIGLLLFLIYTVVSSMFM", "output": "Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step."}]}
+{"id": "function_test_2173", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSDNAHNLLYDKFELPEAVKMLPVEGLPIDKHARFIAEPLERGMGHTLGNALRRALLIGLEAPAIISFAMTGVLHEYMAIEGVIEDVTNIILNLKGALLKKYPMQDSSLGRTTQVLKASISIDASDLAAANGQKEVTLQDLLQEGDFEAVNPDQVIFTVTQPIQLEVVLRIAFGRGYTPSERIVLEDKGVYEIVLDAAFSPVTLVNYFVEDTRVGQDTDFDRLVLIVETDGRVTPKEALAFSTQILTKHFSIFENMDEKKIVFEEAISIEKENKDDILHKLILGINEIELSVRSTNCLSNANIETIGELVIMPEPRLLQFRNFGKKSLCEIKNKLKEMKLELGMDLTQFGVGLDNVKEKMKWYAEKIRAKNIKG", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_2174", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTDVTLKALAAERQVSVDRLVQQFADAGIRKSADDSVSAQEKQTLLAHLNREAVSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERLAAEEQAQREAEEQARREAEEQAKREAQQKAEREAAEQAKREAAEKAKREAAEKDKVSNQQTDDMTKTAQAEKARRENEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTATPEPVEDTSDYHVTTSQHARQAEDENDREVEGGRGRGRNAKAARPAKKGKHAESKADREEARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAPVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETDNGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAGVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSIPVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASNAILVGFNVRADASARKVIESESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGTIKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRVGDMIEVFEIIEIQRTIA", "output": "One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)."}]}
+{"id": "function_test_2175", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPLKSLKNRLNQHFELSPRYGSVKKIMPNIVYADGFNPSVGDVVKIEKSDGTECVGMVVVAEKEQFGFTPFNFIEGARAGDKVLFLKEGLNFPVGRNLLGRVLNPLGQVIDNKGVLDYERLAPVITTPIAPLKRGLIDEVFSVGVKSIDGLLTCGKGQKLGIFAGSGVGKSTLMGMITRGCLAPIKVIALIGERGREIPEFIEKNLKGDLSSCVLVVATSDDSPLMRKYGAFCAMSVAEYFKNQGLDVLFIMDSVTRFAMAQREIGLALGEPPTSKGYPPSALSLLPQLMERAGKEENKGSITAFFSVLVEGDDLSDPIADQARSILDGHIVLSRELTDYGIYPPINILNSASRVAKDIISESQNLCARKFRRLYALLKENEMLIRIGSYQMGNDKELDEAIKKKALMEQFLVQDENALQPFEQSFQQLEEILR", "output": "Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum."}]}
+{"id": "function_test_2176", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLKIKLEKTTFENAKAECSLVFITNKDFDHVWVKNKKLLETFKYEGEGAFLDQENKILYVGVKEDDVHLLRESACLAVRTLKKLAFKSVKVGVYTCDTHAKDNALLENLKALFLGLKLGLYEYDTFKPNKKESVLKEVIVALELHKHCEKTCANSLEKSAKEALKYAEIMTESLNIVRDLVNTPPMIGTPVYMAEVAQKVAKENHLEIHVHDEKFLEEKKMNAFLAVNKASLAVNPPRLIHLVYKPKKAKKKIALVGKGLTYDCGGLSLKPADYMVTMKADKGGGSAVIGLLNALAKLGVEAEVHGIIGATENMIGPAAYKPDDILISKEGKSIEVRNTDAEGRLVLADCLSYAQDLSPDVIVDFATLTGACVVGLGEFTSAIMGHNEELKNLFETSGLESGELLAKLPFNRHLKKLIESKIADVCNISSSRYGGAITAGLFLNEFIRDEFKDKWLHIDIAGPAYVEKEWDVNSFGASGAGVRACTAFVEELLKKA", "output": "Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)."}]}
+{"id": "function_test_2177", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MATVKVIDFIQTPFDFLIVGGGTAGLVLAARLSEEPGIQVGVIEAGSLRLGDPKVDLPTGPGQMLGDPGYDWNFESIPQAGANAKAYHIPRGRMLGGSSGINFMSYNRPSAEDIDDWANKLGVKGWTWSELLPYFKRSENLEPIEPSASCPVSPKVHGTGGPIHTSIGPWQAPIEESLLAAFDEAARLQRPAEPYSGAHLGFYRSLFTLDRTSTPVRSYAVSGYYAPVMGRPNLKVLENAQVCRILLSDASDGIPVAEGVELHHAGARYAVSARREVILSAGSVQSPQLLELSGIGDPSVLEGAGIACRVANTDVGSNLQEHTMSAVSYECADGIMSVDSLFKDPALLEEHQSLYAKNHSGALSGSVSLMGFTPYSSLSTETQVDATMARIFDAPSVSGRLSQQNASYQRRQQEAVAARMQNRWSADIQFIGTPAYFNTAAGYASCAKIMSGPPVGYSACYSIVVSNMYPLSRGSVHVRTSNPMDAPAIDPGFLSHPVDVDVLAAGIVFADRVFRSTLLNGKVRRRVSPPAGLDLSNMDEARQFVRNHIVPYHHALGTCAMGQVVDEKLRVKGVRRLRVVDASVMPMQVSAAIMATVYAIAERASDIIKKDCGFGRRLRAHI", "output": "Dehydrogenase; part of the gene cluster that mediates the biosynthesis of the mycotoxin citrinin, a hepato-nephrotoxic compound to humans due to inhibition of respiration complex III . The pathway begins with the synthesis of a keto-aldehyde intermediate by the citrinin PKS (pksCT) from successive condensations of 4 malonyl-CoA units, presumably with a simple acetyl-CoA starter unit . Release of the keto-aldehyde intermediate is consistent with the presence of the C-terminal reductive release domain . Mp11 collaborates with pksCT by catalyzing the hydrolysis of ACP-bound acyl intermediates to free the ACP from stalled intermediates (By similarity). Mpl2 then catalyzes the oxidation of the C-12 methyl of the ketone intermediate to an alcohol intermediate which is further oxidized by the oxidoreductase mpl7 to produce a bisaldehyde intermediate . The fourth catalytic step is catalyzed by the mpl4 aldehyde dehydrogenase . The final transformation is the reduction of C-3 by mpl6 to provide the chemically stable citrinin nucleus ."}]}
+{"id": "function_test_2178", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSTRRDLPQSPYLAAVAGRKPSRVPVWFMRQAGRSLPEYRALRRQHSMLAACFEPEVACEVTMQPIRRYHVDAAILFSDIVVPLRAAGVDLDIVADVGPVIAAPVRTVADVDAIKPIDSQSIAPVLDAVELLVAELGDTPLIGFAGAPFTLASYLVEGGPSRHHARTKAMMLAEPATWHALMTKLTDLTIEFLLGQIRAGVDAIQVFDSWAGMLSLADYRQYALPHSARVFATLAEHGVPMTHFGVGTAELLGAMSEAVKPGTAKVVGVDWRTALADAAARVQPGTALQGNLDPVVLLAGWPAVERAARAVVDDGRRAVDAGAAGYVFNLGHGVLPQTDPGVLTDLVSLVHSL", "output": "Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III."}]}
+{"id": "function_test_2179", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAFKYHKVAIIGKHYKKEVSQMVETLYAYLQQQGLEIIIENDTAVDTSLVNVAIASLKEIALRCDVAIVVGGDGNFLKASRLLALYSNIPVIGINKGKLGFLTTLAADDNALKNDLYAILKGDSSVTKMSMLKCRVDNNLRAPLEASIALNEIAITASRGLMFGLKVFIDGRYAFDQRGDGLIVSTPTGSTAHAMSAGGPILNPNQNSVVLVPICSHSLNSRPLVISDESVIDIYITDYNDPEPVLSIDGRHDTILKAHQKVTIQKARKKVTVLHTKDYNYYDTLREKLGWSKVLF", "output": "Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP."}]}
+{"id": "function_test_2180", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDTMRQRILVVDDDPSLAEMLTIVLRGEGFDTAVIGDGSQALTAVRELRPDLVLLDLMLPGMNGIDVCRVLRADSGVPIVMLTAKTDTVDVVLGLESGADDYVMKPFKPKELVARVRARLRRNEDEPAEMLSIGDVEIDVPAHKVTRQGEQISLTPLEFDLLVALARKPRQVFTRDVLLEQVWGYRHPADTRLVNVHVQRLRAKVEKDPENPQVVLTVRGVGYKAGPP", "output": "Member of the two-component regulatory system MtrA/MtrB, responding to environmental signals (Probable). Controls expression of a number of genes including dnaA, ripA, fbpB and probably itself. Probably plays a role in cell division."}]}
+{"id": "function_test_2181", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKITADASDPAKRKTAALCGFVLEGAAGAAGLGGPGLDDLIKEAIGKNGGKKGRISMTGTPGMPSERVILAGLGPAGKVTSDGIRSEAGRLARQVRDMGLADFAVAAPSILDPAEEAALIVEGAELALYSFDEFKAEKAGNSPRLHILGGGPSAARAIKDAQSITAGVAFARGLANMPPNECPPDKLGRAAVKMCTGKKMRCIVLKKPELKKGGFGGIIAVGQGSSNEPRLIIVEYNGGKKGQKPIVLVGKAVTFDTGGISIKPGEKMDEMKFDKCGGCTVLGIMKAVEDLALPVNVIGIVPSVENMPGGSSYRPGDIVKLYSGKTAEILNTDAEGRLILADALSYGEKKYAPSEIIDFATLTGACIVALGNNVAGMVSNDDAFAKRIEGASERTAEEVWRLPINDDYMSMIKSEVADMRNLGMGRAAGTITAAAFLKNAIGDTPWVHLDIAGTAWNQPATKKKPYNPGGATGFGVRLVAGYLKGRAQ", "output": "Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides."}]}
+{"id": "function_test_2182", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKLQAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR", "output": "Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate."}]}
+{"id": "function_test_2183", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDNPARKQRGAEKTARIPIKIVPAERLKKPDWIRIRLGAGAEAERFNEIKQTLREHKLHTVCEEASCPNIHECFGKGTATFMIMGDICTRRCPFCDVGHGRPEPLNPNEPTDLARTIAAMRLNYVVITSVDRDDLRDGGAQHFVDCIRETRAASPSTTIEVLVPDFRGRMEIALEIFNQAPPDVMNHNMETVPRLYKQARPGADYAYSLRLLKEFKAGHPDVLTKSGLMVGLGETDDEILDVMRDLRAHDVDMLTIGQYLQPSGGHLPVLRYVHPDTFKMFETEALRMGFRNAACGPMVRSSYWADQQAHGAGVV", "output": "Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives."}]}
+{"id": "function_test_2184", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSNIHEHKILILDFGSQYTQLIARRIREIGVYCELWAWDVTEAQIREFAPNGIVLAGGPESVTEDNSPRAPEYVFDAGVPVLGICYGMQTMSEQLGGKVIQGVGEREFGYAQVEVLTDSALLRHIEDGISDAGKPVLDVWMSHGDKVSAIPEGFVAVAKTETCPFAVMANEDKKFYGVQFHPEVTHTRQGKRMLEHFVMDICGCDNKWQPASIIEDAVERIKAQVGDDEVILGLSGGVDSSVTAMLLHRAIGERLTCVFVDNGLLRLNEAKQVLEMFGDHFGLNIVHVDAENRFLEALKGENDPEAKRKIIGRVFVEIFDEEASKCVNAKWLAQGTIYPDVIESAGSATGKAHVIKSHHNVGGLPDDMELGLVEPLRELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHRADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVDGISRVVYDISGKPPATIEWE", "output": "Catalyzes the synthesis of GMP from XMP."}]}
+{"id": "function_test_2185", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSFAPLQNDTFLRACRRQATDYTPLWLMRQAGRYLPEYKATRAKAGSFMGLATNVEYATEVTLQPLERFPLDAAILFSDILTVPDAMGLGLSFAEGEGPRFAKAVRDEADVAALAVPDLDKLRYVFDAVTSIRRALNGRVPLIGFSGSPWTLACYMVEGKGSDDYRLVKTLMYSRPDLMHRILAVNADAVAAYLNAQIDAGAQAVMVFDSWGGVLADGCFQQFSLEYTRRVLAQLKRTGVDGQDVPRIVFTKGGGIWLDDMKDIDCEVLGLDWTAHLGKARAIVGGQVGGPGKALQGNIDPNVLFAPPEAVAAQVRAVLDSFGTPHTDKTTTGPTHIFNLGHGISQFTPPEHVAALVEAVHGYSRSLRQR", "output": "Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III."}]}
+{"id": "function_test_2186", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSRSARRKTSALNTVLRVVEVFASIQGEGPFTGTYSVFVRLAGCNLRCPFCDTRYAWSLEAGKPLGVEELVEEIARYEPSLVVITGGEPLLQRHPLNSLVEGLESLGLRVQLETNGILPAPARDEQLWRVYHVVSPKDVPVRVPGAKLHPSWVDYARATGRAWFKFLVANEQHVREVAEYVAKLGIPRSRVYIMPLTPEKLDMKELLELHSRIASLAVKWRLNFSPRLHLLVQLP", "output": "Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds."}]}
+{"id": "function_test_2187", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLKVLAIETSCDETSVSVVSNSNDIYKIHSNIVASQIEDHSKWGGVVPELAARKHLELIPFVLEEALEESKISIEEIDAIASTVTPGLVGCLRVGSITARSLCTLYSKPFLGIHHLEGHLSSILFSKNYPKPPFLTLLVSGGHTELIKIGERRIMQRLGRSYDDAAGEAFDKVGRLLGLSYPGGPAIAEIAKKGNSLKFNLPKCKISDKKGGFLKYDFSFSGLKTAVLRLVEKIRLNGDEIPIPDIAASFERVVSEVLVERTIKCAVDYDLDNVVVVGGVAANDTLRKMMISEAGKKSIKVHLAPLNLCTDNAAMIGAAALFRLKFKAHESSLELGISGRLPIDQANTLYANKPPF", "output": "Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction."}]}
+{"id": "function_test_2188", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRKTHINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGLKQTPQHKTDKFAELVCSNSLRGAAITNAVGLLKEEMRRLDSVIIKAAEYTQVPAGGALAVDREGFSDFVTKEVSNHPLVEVIREEITEIPQDELTIIATGPLTSDNLANKIREFNGADGFYFYDAAAPIIDANSINFDKVYKKSRYDKGEADYINCPMTKEEFQAFQEALISAEEAPLNSFEDLKVFEGCMPIEEMAKRGYKTMLFGPMKPVGLEYPDEYKGPRDGEFRTPYAVVQLRQDNASASLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLKQTFQSRKQENLFFAGQMTGVEGYVESAASGLVAGINAAKLFNDEEVVIFPKITAIGSLPYYITHTDSKHFQPMNVTFGIVEELDGPRIRDKKERYTKVAERSLNTLTDIISKENLA", "output": "Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs."}]}
+{"id": "function_test_2189", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTQLVLIRHGESTWNLENRFTGWTDVELTPTGVAQAQQAGRLLKQAGIDFDTVYTSVLKRAIWTAWHCLDGMDRTWLPVIKDWRLNERHYGGLQGLNKADMAKQFGDEQVLLWRRSYDVPPPPLEANDPRSERSDVRYAKLAANQVPLTECLKDTVARVLPLWYGTLAPAIAAGQRLVIVAHGNSIRALVKHLNNISDADIVGVNIPNGIPLVYDLDANLKPTSKYYLGGADAAAQAASVSALQADG", "output": "Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate."}]}
+{"id": "function_test_2190", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSTAYFDADCDLEPSLKSLFSLKTLKWIFVGGKGGVGKTTTSCSIASRLAEERESVLILSTDPAHNLSDAFVQKFSNAPTLVNGYKNLYAMELDASYQQAVEFKLKEENSLFSKFLPDLISALPGIDEALGFATLMQSVKSMSYSVIVFDTAPTGHTLRLLSFPSLLEKGLSKLFSIKQNMSGALQLINSVSGNAIEEETLNSKLEDLKAITTSVKETFQDPSKTTFVCVCIPEFLSVYETERLIQELAKQSISCSHIVVNQVMFPIDLPSGNDQGESVLKDSSELLKLEDIPSDHSKLVEFTEKIVCSYNKLLSYSKLLYSKYYSKRNMQMKYLEQIRDLYSYDFHVAYIPTLNNEVSKIRVLIS", "output": "ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting."}]}
+{"id": "function_test_2191", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MFSSLYPLARASLFKMDAEDAHHLTLRMLGAAGRTGLACALSPRVPDAPRTVMGLSFRNPVGLAAGLDKDGAAIDGFAALGFGFIEVGTVTPRAQPGNPRPRMFRLPEADAIINRMGFNNSGVDQFVKNVQAARYRGVLGLNIGKNADTPIERAADDYLYCLERVYPFASYVTINISSPNTKNLRQLQGAGELDALLAALKDKQRRLADLHGKLVPLALKIAPDLDDEQVKEIAATLLRHDIEGVIATNTTLSREAVKGLPHADEAGGLSGRPVFDASNAVIRKLRAELGDAVPIIGVGGIFSGEDARAKLAAGAALVQLYTGFIYRGPALVAECVKAIARG", "output": "Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor."}]}
+{"id": "function_test_2192", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGQCVTKCKNPSSTLGSKNGERESSKPHKRSSSHKDEHLSICGKASREILVNGTKKGDVSLEASQPLAAGGDTKKKEQGTGAELSSVQRIEELFWRYKDEREDAILEEGMERFCNDLYVDPTEFRVLVLAWKFQAATMCKFTRREFFEGCKAINADGIEGICARFPSLLNEAKQEDKFKDLYRFTFQFGLDSEEGQRSLHREIAIALWKLVFTQNKPLILDQWLDFLTENPSGIKGISRDTWNMFLNFTQVIGPDLSNYSEDEAWPSLFDTFVEWEMERRKNEEETKCIPCSGTDDQSTEGQT", "output": "Contributes to the neddylation of all cullins by transferring NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes. At the cell membrane, can promote and as well inhibit cullins neddylation."}]}
+{"id": "function_test_2193", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLKIAVPNKGSLSERAMEILAEAGYAGRGDSKSLNVFDEANNVEFFFLRPKDIAIYVAGGQLDLGITGRDLARDSQADVHEVLSLGFGSSTFRYAAPADEEWSIEKLDGKRIATSYPNLVRDDLAARGLSAEVLRLDGAVEVSIKLGVADAIADVVSTGRTLRQQGLAPFGEVLCTSEAVIVGRKDEKVTPEQQILLRRIQGILHAQNFLMLDYNVDRDNLDAATAVTPGLSGPTVSPLARDNWVAVRAMVPRRSANAIMDKLAGLGAEAILASEIRIARI", "output": "Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity."}]}
+{"id": "function_test_2194", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRLTDIEIEQALDNGTIVIEPRPSIDAISGVSVDVRLGGQFRVFKDHTAPFIDLSGPSGEMQAALDRVMSEIIEIPDGEAFFLHPGELALAVTYESVTLPADIVGWLDGRSSLARLGLMVHVTAHRIDPGWQGKIVLEFYNSGKLPLALRPRMTIGALNFERLSGPVARPYNTRKNAKYKDQQEAVASRISQD", "output": "Catalyzes the deamination of dCTP to dUTP."}]}
+{"id": "function_test_2195", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQETGIRNGAFGADKFGLKNLKQLHWNLGAPQLYQYSLAAGEATLSADGALCADTGEFTGRSPKDKFTVRDASTEKMWWAGNQSITPEQFEALYQDFIKHAEGKTLFAQDLYGGADPTFRIKTRVFTELAWHSLFIRTLLIRPETIELDTFVPELTIIDMPSFRADPMRHGVRSQNVVAIDFARKIVLIGGSYYAGEMKKSVFTTLNYYLPARGVMPMHCSANVGPKGDTAIFFGLSGTGKTTLSADPNRTLIGDDEHGWGPSGVFNFEGGCYAKCIKLSQEAEPQIFAASNRFGAVLENVVLDEDSRVPDFDDGSKTENTRSAYPLDYIPNASRTGRAPHPKNVVMLAADAFGVLPPIAKLSPAQAMYHFLSGYTAKVAGTERGLGSEPQPEFSTCFGSPFLPLDPSVYGNMLRQLIADHNVDCWLVNTGWTGGKYGTGSRMPIKVTRALLTAALDGSLRNVEFRTDKYFGFAVPTALPGVPSEILDPVNTWKDKVEFDKTARALVGMFQKNFAKFEAQVDADVRAAAPDVKLAAE", "output": "Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA."}]}
+{"id": "function_test_2196", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAEKRNIFLVGPMGAGKSTIGRHLAQQLHMEFIDSDTVIEERTGADIAWVFDVEGEEGFRKREEAVINDLTEQQGIVLATGGGSVISKENRNRLSARGIVVYLETTIEKQLARTNRDKKRPLLQTDCPREVLEQLAEDRNPLYEEIADITVRTDDQSAKVVANQIVKMLEEHIM", "output": "Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate."}]}
+{"id": "function_test_2197", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MANGKVIQVIGSVVDVEFSADSMPALFNALEIPRENGKMVLEVQSHVGNNRVKCLSFTPTDGLERGAEVIDTTRPLSVPVGRGTLGRIFNVLGEALDNRGDVKSEKTMPIHRLAPGMDELESSAQVLETGIKVIDLIAPFARGGKIGALGGAGVGKTVLIQELIRNIATEHEGFSVFAGVGERSREGNDLWHEMEDSGVLPKTTMVFGQMNELPAVRLRIALTGLTMAEYFRDEERQDVLLFIDNIYRYTLAGMEVSALLGRMPSAVGYQPTLATEMGALQERIASTKQGSITSFQAVYVPADDYTDPGVVATFGHLDAMIALERSLAEQALYPAVDPLASNSRILDPQVVGEEHYKVARDVQKVLQRYKDLQDVIAILGMEELSEEDKLTVARARRIQRFLTQPMFVSEVFTGRPGQYVSLTETIRGFKEILEGKHDSLPEQAFYMVGTIDDAVAEAKKLSAV", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits."}]}
+{"id": "function_test_2198", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSRYVFTSESVTEGHPDKICDQVSDAVLDALLAQDSSSRVACETVVNTGLCMITGEVTSKAQVDFIHLVRDVIREIGYSGARAGGFDANSCAVLVALDQQSPDIAQGVDEADDHEGDPLDKVGAGDQGIMFGYACNETPELMPLPISLAHRLSRRLAEVRHNGTLDYLLPDGKTQVSVVYENDKPVAIDTILISTQHTAEVAGLSDEQQVRERISDDLWTHVVEPATADLPLKPSKDSTRYLVNPTGKFVVGGPQGDAGLTGRKIIVDTYGGYARHGGGAFSGKDPTKVDRSAAYAARYVAKCLVAAGLAQRAEVQLSYAIGVAKPVSILVESFGTGKVSNAELTELVQQHFDLRPGAIIQQFKLREMPALSGGRFYRDTAAYGHFGRPDLKLPWEDVENKASTLLQAEASRLQQGNTL", "output": "Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme."}]}
+{"id": "function_test_2199", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRSDVIKKGLERAPHRSLLKALGITDDEMRRPFIGIVSSWNEIIPGHVHLDKVVEAVKAGVRMAGGVPFVFPTIGICDGIAMDHRGMKFSLPSRELIADSIEIVASGFPFDGLVFVPNCDKITPGMMMAMGRLNIPSVLISGGPMLAGRYNGRDIDLITVFEAVGGYKVGKVDEETLKAIEDLACPGAGSCAGLFTANTMNSLAEALGIAPRGNGTVPAVHAKRLRMAKEAGMLVVELVKRDVKPRDIVTLDSFMNAVMVDLATGGSTNTVLHLKAIAESFGIDFDIKLFDELSRKIPHICNISPVGPYHIQDLDDAGGIYAVMKRLQENGLLKEDAMTIYLRKIGDLVREAKILNEDVIRPFDNPYHKEGGLGILFGNLAPEGAVAKLSGVPEKMMHHVGPAVVFEDGEEATKAILSGKIKKGDVVVIRYEGPKGGPGMREMLSPTSAIVGMGLAEDVALITDGRFSGGSHGAVIGHVSPEAAEGGPIGIVKDGDLIEIDFEKRTLNLLISDEEFERRMKEFTPLVKEVDSDYLRRYAFFVQSASKGAIFRKP", "output": "Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively."}]}
+{"id": "function_test_2200", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSIILGIDPGSRVTGYGVIRQTGRHLEYLGSGAIRTQVEDLPTRLKRIYAGVTEIITQFQPDMFAIEQVFMAKNADSALKLGQARGTAIVAAVNHDLPVFEYAARLVKQTVVGIGSADKVQVQEMVTRILKLSDKPQADAADALAIAITHAHSIQHSLHIANSVKMTETQEKMTALLKTRYSRGRFRLKI", "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."}]}
+{"id": "function_test_2201", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKRTNYAGDTNEQQVGQEVVLKGWVAKRRNLGGLIFIDLWDREGIVQLVFNEKENPEAFEIANAVRNQYVLEVQGKVQLRAEKEINPDMKTGKVEVAVDEVKVLAKSETTPFDITDGVDASEDLRMKYRYLDLRRPEMMRNLKLRSKVASIVHNYYDNEGFMDVETPDLTRSTPEGARDYIVPSRVYPGHFYALPQSPQLFKQLLMAAGVDKYYQLARCFRDEDLRGDRQPEFTQIDTEMSFATPEDIQTVTEGLIKRVMKEIVGVDVKTPFPRMEWQEAMDKYGSDKPDTRFGMLIHDLSDIVKDSSFKVFANTVADGNYVRAIRVPGGADKYSRKDISKYEEYIKRFGAKGLAWVKVTADGYNGPVAKFLNDQVAQINEEMDAKEGDLILFVAGSFHVVSDSLGYLRRAIAEELDMIKPDQWNYLWVVNWPMFEYDEGFGKWIAAHHPFTMLNEEDLHYLEDGEDPHKAHAQSYDIILNGNEIGGGSIRIHDPKIQEKVLKALGYTKERAEARFGFLLKALTMGMPPEGGLAFGLDRWVMLLAQADSIRDVIPFPKNSKAVEPLTAAPGKVSEQQLDDLKIEFDEKIDYKLDQDPDEQ", "output": "Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)."}]}
+{"id": "function_test_2202", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAFLALGINHKTASVDVRERVAFTPEQLVDALQQLCRLTSSREAAILSTCNRSELYIEQDHLSADAVLQWLADYHRLSLDELRASAYVHEEHEAVKHMMRVASGLDSLVLGEPQILGQMKSAYAVAREAGTVGPLLGRLFQATFSAAKQVRTDTAIGENPVSVAFAAVSLAKQIFADLGRSQALLIGAGETITLVARHLHEQGVRRIVVANRTLERASILAEQFGAHAVLLADIPQELANSDIVISSTASQLPILGKGAVESALKQRRHKPIFMVDIAVPRDIETEVGELDDVYLYTVDDLHDVVAENLKSRQGAAQAAEELVSVGAEDFMLRLRELAAVDVLRAYRQQSERLRDEELQKALRLLANGGNPEDVLAQLARGLTNKLLHAPSVQLKKLSAEGRLDALAMAQELFALNEGSTDKSPQ", "output": "Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA)."}]}
+{"id": "function_test_2203", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKKLIIAGKEFNSRLFLGTGKFNSNTVMEEAILASGCEMVTVAMKRIELDDKEDDMLKHIIHPHIQLLPNTSGVRTAEEAVFAAQMAREAFGTNWLKLEIHPDPRYLLPDSTETLKATEELVKLGFVVLPYCQADPTLCKRLEEAGAATVMPLAAPIGTNKGLQTRDFLRIIIEQASVPVVVDAGIGAPSHATEAMEMGADACLVNTAIAVAGQPVEMAIAFKEAVIAGRRAYEAGLGAVGQNLIASASSPLTSFLD", "output": "Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S."}]}
+{"id": "function_test_2204", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKDLPIIALDFESKEKVNQFLDLFDESLFVKVGMELFYQEGPQLINEIKERGHDVFLDLKLHDIPNTVGKAMEGLAKLNVDLVNVHAAGGVKMMSEAIKGLRKHNQDTKIIAVTQLTSTTEDMLRHEQNIQTSIEEAVLNYAKLANAAGLDGVVCSPLESRMLTEKLGTSFLKVTPGIRPKGASQNDQHRITTPEEARQLGSTHIVVGRPITQSDNPVESYHKIKESWLV", "output": "Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP)."}]}
+{"id": "function_test_2205", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQVKDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLAHVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA", "output": "Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin."}]}
+{"id": "function_test_2206", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEKIKIIVASDSIGETAELVARAGISQFNPKQCKNELLRYPYIESFEDVDEVIQVAKDTNAIIVYTLIKPEMKQYMSEKVAEFQLKSVDIMGPLMDLLSASVEEKPYNEPGIVHRLDDAYFKKIDAIEFAVKYDDGKDPKGLPKADIVLLGISRTSKTPLSQYLAHKSYKVMNVPIVPEVTPPDGLYDIDPKKCIALKISEEKLNRIRKERLKQLGLGDTARYATEARIQEELNYFEEIVSEIGCPVIDVSQKAIEETANDIIHYIEQNKSK", "output": "Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation."}]}
+{"id": "function_test_2207", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSLVKPLTARQQEVYNFLKHYIETTGMPPTRAEISRELGFRSPNAAEEHLKALARKGAVEILAGTSRGIRLLLDAANDEPEGLPLIGQVAAGEPILAEQHIEGTYRVDPDMFKPQADFLLKVNGQSMKNIGILDGDLLAVHSTKDVRNGQVIVARIEDEVTVKRLERKGDVIYLHAENEEFAPIVVNLREQERFEIEGIAVGIIRNNAWM", "output": "Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair."}]}
+{"id": "function_test_2208", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSVNDQITHIGKTLSTTASAFLNYQKSNSNTQDVLTNNGPYKNLLSNTVNNASSTSYFYKRTEHGRFVKNASNTFEDIYSKTRRGDVFRNKFTDNKTCFRMLTYISDDLLNEIPTKEGLKSDADGKLLTEGGENENLRKNASKKETSLFQGFKSYLPIAELAIENTERLNYDTNGTSGTVGAKDVMSKTNERDEIHTELPNFQDSFLIPPGVETKKISSSYSPSALKSFSQTLVNSLEFLNIQKNSTLSEIRDIEVEVENLRQKKEKLLGKIANIEQNQLLLEDNLKQIDDRLDFLEEYGLEVIEANSDENAEDDGMSERKALKNDAIRNEGVTTESISSEASNLPPRRRQQLRDDNSLNRLGAFYSKSKKRHRKSFPTFQQLYEPGTKIGSIMSTHDDFLTCLDFDAPFGTLCTAGYLDHTVKIWDLSKQNKIGELAGHLATINCMQINRDYGTLVTGGRDAALKLWNLNLAQQLYQETQNLTSPTNHIDSPCVYTFEAHTDEVTALSLDPSFLVSGSQDRTIRQWDLRSGKCLQTIDLSFANVLTTSTNVDLSKSTLLTQRNERPSIGALQSFDAALATGTKDGVVRLWDLRSGKVIRTLKGHTDAITSLKFDSACLVTGSYDRTVRIWDLRTGLLNKFHAYSAPVLSLDLFQENAAVVVADEPSVQIYDSEKDESWSCVEQGNETSVSTVKYKENYMVEGRENGDVNIWAV", "output": "Involved in mitochondrial fission. Has a partially redundant function to CAF4 in acting as an adapter protein, binding to FIS1 on the mitochondrial outer membrane and recruiting the dynamin-like GTPase DNM1 to form mitochondrial fission complexes. Formation of these complexes is required to promote constriction and fission of the mitochondrial compartment at a late step in mitochondrial division (By similarity)."}]}
+{"id": "function_test_2209", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKLLEDKILKEGILLEGNILKVDSFLNHQMDVKLFNEIGKEFKRRFEGCSINKILTIEASGIGIATIVSQYFDFCPVVFAKKVDAANMDKDTYESKVHSFTKNKTYNVRVSKKYINKGDKILLIDDFLANGCAALGLIDIIKQGGAELIGVGIAIEKGFQKGRKELEKVGAKVESLAILDKIENDKVYFK", "output": "Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis."}]}
+{"id": "function_test_2210", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSLMLEPNPTQIKEERIYAEMGLTDEEFAMIEKILGRLPNYTETGLFSVMWSEHCSYKNSKPVLRKFPTTGERVLQGPGEGAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDIFSMGARPVALLNSLRFGELQSPRVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDPCYEGNPLVNAMCVGLIHHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESSEAKRPAVQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQRETGMTPYEMMLSESQERMLIVVKKGREQEVVELFEKYGLAAVAMGKVTEDKMLRLFHKGEMVAEVPADALAEEAPIYHKPSKEAAYFREFQEMKMKTPKVDNYKETLLALLQQPTIASKEWVYDQYDYQVRTSTVVTPGSDAAVVRVRGTEKALAITTDCNSRYIYLDPETGGKIAVAEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLQTPVIGGNVSMYNERSGEAVYPTPTVGMVGLVHDLKHVTTQEFKQAGDLIYVMGETKAEFGGSELQKMMYGKIFGQSPSIDLEVEAKRQKQLLEAIQAGLVQSAHDVAEGGLAVAIAESAIGAKGLGATVKLAGEATAALFAESQSRFVVTVKREQQEAFEKVVEAIQVGEVTNTNEVTIHNEENEVLLTANVDEMRKAWKGAIPCLLK", "output": "Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL."}]}
+{"id": "function_test_2211", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIKLVLIRHGQSLWNLENRFTGWTDVDLSENGLHEARTAGAILKKNGYTFDVAYTSVLKRAIRTLWIILHEMDLAWVPVHKSWKLNERHYGALQGLNKDETAKKYGEEQVHIWRRSTNVRPPALAEDDPRYEVTDPRYKRLKKGEFPLTECLEDTEKRVLEFWHKEIAPMLCSNQKVIISSHGNTIRSLVKYLDHLSDDGVVSLNIPTGIPLVYELDEHLHPIRHYYLNMDGEVQEGVIPKHISF", "output": "Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate."}]}
+{"id": "function_test_2212", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNSVPASAYLTLAIILFCIGLFGALTKRNTVIVLVCMELMLNAANLNLVAFSKLGFFPNLTGQIFSLFTMSVAAAEAAVGLAILIALYRNRTTVNIDEMDKLKG", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_2213", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAVLKPVRLGVNVDHVATVRNARGGALPDPVRAAALAKAAGAHGITAHLREDRRHIRDADMERLKAEIDLPLNFEMAATDEMVAIACRVRPNACCLVPERREERTTEGGLDAAGQRAELAPRIARLKAAGIRVSLFIAADPAQIAAAAELGADIVELHTGAWCDAVTEGRHVEAEAEFVRLKAGARQAAGLGLEVHAGHGLDYATAERIAAFPQIVELNIGHFLIGEAIFVGLDQAIARMRAAIAAGRAAVGDGAAA", "output": "Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate."}]}
+{"id": "function_test_2214", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKKAVCIMSGGMDSTLCAVMAKRAGYDVVALHFDYNQRTMKREKRAFDEICERLGVVKKINLDVSFIAQIGGNALTDTSMQIRKDGVSNDVPNTYVPFRNGVFISIAAALAEKEGAQAIYIGVVEEDSSGYPDCKESFIKSINEAINLGTSADFSCEIITPLVNLSKADIVSKSLELNSPIELTWSCYESEDEACGLCDSCRLRLNGFKKANAVDKIPYKK", "output": "Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))."}]}
+{"id": "function_test_2215", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRSHYCTDLSKADIGKEVILCGWANTYRDHGGVVFIDLRDVSGLIQLVCDPADSKEAHDVAAKVRDEYVLKAKGKVRARGEGLTNPKLKTGEIEVIVSELIIENPSEPLPFMIGDESVNEDIRLKYRFLDLRSERLQNIFKMRSRAAIAARNSLDKMGFIEFETPVLTRATPEGARDYLVPSRVYPGQFYALPQSPQLFKQLLMCSGFDKYFQIAKCFRDEDLRADRQPEFTQIDIEMSFVEQEDIINMAETMLKDIFKACGHDIKTPFRRMSYKEATETYGSDKPDLRYDLKMIDVIDIFERSSNEIFSSIAKDKKKNRIKALKVPNGDNIFSKREMNRFEEFVRKFGAQGLGYFQMKEDGLKGPLCKFFEQSDLDEIVSRCELKVGDVVFFGAGKKKIVLDYMGRFRIFLAEQMGIIDQDRLEFLWVLDFPMFEQNDDGSYSAMHHPFTMPKNIDEPDLEDILSIAHDVVLNGFELGGGSIRIHKNDIQQKVFKLLGIDEAEQREKFGFLLDALTFGAPPHGGIAIGFDRLNMLVNKASSIRDVIAFPKTQRAQCPLTKAPSYASNEQLRELGLRIREKEQKA", "output": "Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn)."}]}
+{"id": "function_test_2216", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDLEKIYKDAGAYLEGHFLLSSGNHSQFYLQSAKVLEDPALAGKLADELAAVIEKFGIKFDSVCSPALGGILAGYELARAAKKRFIFTERVEKVMSLRRGFEVKKGEKFIVCEDIITTGGSALEAAHVIESLGGEVVGFAALANRGFCKVANLGNDSKPNAKLPSDKPFFALGNFEFEIYEPEHCPLCKSGSKAIKPGSRGN", "output": "Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)."}]}
+{"id": "function_test_2217", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTITPQNLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIGLNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNKDEFYLLVLIAALGGILLANANHLASLFLGIELISLPLFGLVGYAFRQKRSLEASIKYTILSAAASSFLLFGMALVYAQSGDLSFVALGKNLGDGMLNEPLLLAGFGLMIVGLGFKLSLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAIRVVLAIIAFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQTGEMSMEAVGVYLAGYLFSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILAAVMTVMMLSLAGIPMTLGFIGKFYVLAVGVQAHLWWLVGAVVVGSAIGLYYYLRVAVSLYLHAPEQPGRDAPSNWQYSAGGIVVLISALLVLVLGVWPQPLISIVRLAMPLM", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_2218", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRTLWIVAVCLIGVEGSLLEFGKMILEETGKLAIPSYSSYGCYCGWGGKGTPKDATDRCCFVHDCCYGNLPDCNPKSDRYKYKRVNGAIVCEKGTSCENRICECDKAAAICFRQNLNTYSKKYMLYPDFLCKGELRC", "output": "Snake venom phospholipase A2 (PLA2) that is neurotoxic. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (By similarity)."}]}
+{"id": "function_test_2219", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MFIDSAKFTVISGKGGQGCASFRREKFVVQGGPDGGDGGKGGNVYFLVDNNTDTLSSYKGRKLFKAENGKQGMGGNMTGKSGDSLVLVVPPGTQVIDDETNEVLFDLLENGEKILFLEGGKGGLGNVHFKNSRNQRPTYFQPGLPGSTKNIRLELKLIADVGLVGYPNVGKSTLISVTSNATPEIANYEFTTLTPKLGVVEVGNYNSFVMADIPGIIDGASDGKGLGLEFLKHIERTKTLLFVIDVANYRTMIDQYQVLKEEVAKFSNELSKRNYAIALSKIDGYYGENLEEDIKNFIKELDLEESNSNEFKFETEYPYFVQDTIYSRFDKSKPYFVLPISSLTKYNIKQLEFALYELLGQDK", "output": "An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control."}]}
+{"id": "function_test_2220", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSNKGTERVKRGMAEMQKGGVIMDVVNAEQAKIAEEAGAVAVMALERVPADIRAAGGVARMADPRIVEEVQNAVTIPVMAKARIGHIVEARVLEALGVDYIDESEVLTPADEEFHLNKNEYTVPFVCGCRDLGEATRRIAEGASMLRTKGEPGTGNIVEAVRHMRKVNAQIRKVAAMSEDELMTEAKNLGAPYELLLQIKKDGKLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIFKSDNPAKFAKAIVEATTHFTDYGLIAELSKELGTAMKGIEISNLLPEERMQERGW", "output": "Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively."}]}
+{"id": "function_test_2221", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRAIGLMSGTSMDGIDAALIETDGETVAWLGSALTIPYGAETRALLEGAMADARGVNARTDRPGRLVEAERRITTLHGAAVRALLDSLRLTPADIDVVGFHGQTVLHRPDAALTVQIGLGQALADDLRIPVVADLRAADVAAGGQGAPLVPVFHQALVRGLDLPQPVAVLNIGGVANVTVLEDGADPIACDTGPGNALLDDFMAARTGRPYDDDGASAARGQVDEAAVAEVLGHPFFAAPPPKSLDRNEFRAFVTERLHLAGASTDDGAATLTALSAASIAAVVPLLPKAPKSWIVAGGGARNSTLRAMLAERLGVPVVVAEQVGWSADALEAHAFGFLAVRSLKGLALTFPTTTGAPEPLTGGVLFQPTP", "output": "Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling."}]}
+{"id": "function_test_2222", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIMRPTPDMAMLLAAGLFALGLLGVLVRRNLLFMLMSIEIMLNAAALAFVAAGTRWHAAEGQVMFLMILSLAAAEAAIGLAILLRMHQAGRPTLDADTGNRLKG", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_2223", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSGTDKVRVNVSQTAQTPLHTSAKLPKVGVLLVNLGTPDGTSYGPMRRYLAEFLSDRRVIEWSRLIWYPILYGIVLNTRPRRSGRLYDRIWNHENNESPLRTYTRAQGEKLAKALSDQPNVVVDLAMRYGQPSIESITDRLLQQGCERIVIFPLYPQYSATTTATVNDKFFEALMKKRFMPAIRTVPSYEAEPVYIDALARSVEKHLATLSFKPEVILTSYHGIPKSYSDKGDPYRQQCLETTRLLRERLGLGEDEMRATFQSRFGPEEWLQPYTDETVKELAKNGVKSVAVLNPGFVADCLETVDEIGNEAAEEFLENGGENFSHIPCLNDSEEGMKVIETLVRRELLGWV", "output": "Catalyzes the ferrous insertion into protoporphyrin IX."}]}
+{"id": "function_test_2224", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPEGPEIRRAADHLEAAIKGKLLTDVWFAFAQLKPYESQLTGQMVTRIETRGKALLTHFSNGLTLYSHNQLYGVWRVIDTGEIPHTTRILRVRLQTADKTILLYSASDIEMLTAEQLTTHPFLQRVGPDVLDARLTPEEVKARLLSPRFRNRQFSGLLLDQAFLAGLGNYLRVEILWQSELTGQHKAKDLSEAQLNTLSHALLDIPRLSYATRGQTDENKHHGAQFRFKVFHRDGEACERCGGIIEKTTLSSRPFYWCPHCQK", "output": "Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates."}]}
+{"id": "function_test_2225", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MHNQYGSIFSITTWGESHGPAIGVVIDGCPAGLSLSPEDFLPAMARRRPGQLHTSPRQEPDLVTILSGVYQNKTTGTPISLLIENKDVSSSSYEHLQHCYRPGHAQFAYEGKYGFADNRGGGRASARETASRVAAGVIAKKILLSQGIETLAFLSGFGTLESKNYPKLSDSLIQQVHTSPFYTLLPQEEIQNLLLLNPDDSFGGVVSFITSPLPIGLGEPVFGKLPALLAAGMMSIPAAKGFEIGAGFSSSQMTGSAYLDAFIADESGVSLQSNRCGGALGGISIGQPLEGRVAFKPTSSIKKPCSSVLKDGTPIAYRTPNQGRHDPCVAIRAVAVVEAMLDLTLVDLLLQHRCTQL", "output": "Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system."}]}
+{"id": "function_test_2226", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAVQRTFSIIKPDAVAKNVIGKITTRFEEAGLKIVASKIKQLSKAEAEGFYAEHSARGFFGDLVAFMTSGPVVVQVLEGENAIALNRELMGATNPKEAAAGTIRADFAESIDANAVHGSDSEAAAAREIAYFFAATEVTTR", "output": "Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate."}]}
+{"id": "function_test_2227", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAKPETENPYSKTVLLPETSFPMKADLAKREPGQIKVWKDQKVFLNMKEIRKSKPSFVLHDGPPYANGNFHVGHSLNKILKDIIIKSKTLSGYQTDMIPGWDCHGLPIEVQVLKNLGKEARNTGPSELRKKCREYAAEFVGKQGEDLNRFLCFWDENNKYLTMAPEFEARIVEVFGSLFAKGYIYKGKKPVYWCIDLATAHAEAEIEYQNHVSPSIYVKFAVKGETDTHCLIWTTTPWTLPANLAICFNEELPYSLFQSDAHGRLILADGLKEAVEQKTGITLTKIKSLSNADLKQMVFLHPFLDRESIPLFGNHVTLDAGTGCVHTAPGHGTDDYRVGTAAGLPTLSPVDDYGRYTDEFEMMKGIKIWDANPKIVELLREKNALVHFSEFTHSYPHSWRSKKPLIFRATPQWFFSIDHNGLRDESLKAIDKVQWIPDWGITRIRSMVESRPDWCLSRQRNWGVPIPSFTCKSCGLTHLDDKTIQHFIQIVKKEGIEVWYEKEAKDLLPADTKCSNCGSEDLKQDKDILDVWFDSGVSSFAVFGDSIGKEPADLYLEGSDQHRGWFQSSLWPSMAIRKTPPYKSVLTHGYVLDEKGHAMSKSLGNVINPTTDIINQYGADILRLWVSTQDFRDDVKIGKDSIKTVSEAYRKIRNTFRYLLGNTSAETLTWNLKKEELDTIDKYYLHKLAKLNDEVKKLYDTYQFHQVYHKILGFCTVDLSQDYFEIIRDRMYCDAKESKTRRSSEYTLAVILEVLSKLLAPILSFTTEEVWTSFGKKDSVFYSDFSDLTEWLDESLESKMKPVFETKEDVQKALEEARKLGKLGKSLEAEVVIDGKKDSLPFSSEELALFFVVSHVHFETNGIQEVFSEWKGESGSIQIRKPKHFECPRCWRHVSETEGKLCKRCDEVVSKLSPN", "output": "Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)."}]}
+{"id": "function_test_2228", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKKKTVLTILKKKQSGEKITMLTCYDYVTAKLISSQDIDVLLVGDSLGNVKLGYENTLSVTVDDMIYHTKSVKRGNDGALLITDMPFMSYEITVEDAVKNAARIVKEGGAEAVKVEGGIEIVDRVKAISDAKVPIVGHLGLTPQSINKFGGFKVQGRTEEERGRLIADAEALEKTGAFAVVLEAVPEQLAKEVTERLKIPTIGIGSGRYCDGQVLVVDDMLGMFTDFTPKFVKKYAEIGEMVRTAVKNYIDEVKKGQFPREENTYK", "output": "Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate."}]}
+{"id": "function_test_2229", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNIKPEEITSIIRQQIENFNTNIETIDSGTIIQIGDGIARVYGLEDCMEGELIEFPNDVYGMALNLEQDNVGCVLLGAEEGIKEGNVVKRTKKVVEVPVGEALVGRVVNSLGMPIDGKGPVLTTETRDVEVPAPGVIDRQSVKEPLQTGIKAIDSMIPIGKGQRELIIGDRQTGKTAIAMDTILNQKGKDVICIYVAIGQKQSTVAHIVNDLTKMGAMDYTIVVSSTASDSAPLQYLAPYAGCSMGEYFMHKGKDVLIVYDDLSKHAVAYRTMSLLLRRPPGREAYPGDVFYLHSRLLERSARLSEKLGGGSLTALPIVETLAGDVTAYIPTNVISITDGQIFLESELFNAGQRPAVNAGISVSRVGGNAQIKAMKQVAGTLRLELAQYRELAAFSQFGSDLDKESVKRLEKGKRLVEILKQPQYGPMPVEKEIIILYAAVNNHLIDIPVNKIKEFEKELFNYIDTHYRDIGKDILEHKQLTDELKSKLDKAINDFKNVFLSEI", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit."}]}
+{"id": "function_test_2230", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNEILNTKDINAIGEFFIETWGCQMNEEDSEKLSGMLKKEGYIRTEERENADVIIFNTCCVRENAELKVYGNLGILKGLKSKNPNLIIAVTGCMMQQKGMAETIKKKFPFVDIIIGTHNLHNFPNYLNEVKKKDTSILKIQEKEDSIIENMPIDRKNSMKAFVTIMYGCNNFCTYCIVPYVRGRERSRTPENIEDEIKKLISEGYKEITLLGQNVNSYGKDLEPKVTFADLLERVNTIDGLERVRFMTSHPKDLTDDVIEAIAKCDKLCEQIHLPVQSGSSEILKKMNRHYDREKYLDVVSKIKKLIPNVALSTDIIVGFPGETEKDFEETLSLVKEVEYDSAFTFLYSIRKGTPAAKFEDQVPEDVKHKRFNRLVEVVNEISAKKNKAYEGKIEEVLVEGTSKNDENKLMGRTRTGKLVNFIGDKDSIGKLVNVKIIKANSFSLTGEEI", "output": "Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine."}]}
+{"id": "function_test_2231", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKPLSSPLQQYWQTVVERLPEPLADESLSAQAKSVLTFSDFVQDSVIAHPEWLTELESQPPQADEWQHYSAWWQEALSNVSDEAGLMRELRLFRRRIMVRIAWAQTLALVTEESILLQLSHLAETLIVAARDWLYDACCREWGTPCNAQGEAQPLLILGMGKLGGGELNFSSDIDLIFAWPEHGCTQGGRRELDNAQFFTRMGQRLIKVLDQPTQDGFVYRVDMRLRPFGESGPLVLSFAALEDYYQEQGRDWERYAMVKARIMGDSEGVYANELRAMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLTDNIKLGAGGIREIEFIVQVFQLIRGGREPSLQSRSLLPTLSAIAELHLLSENDAEQLRVAYLFLRRLENLLQSINDEQTQTLPSDELNRARLAWAMDFADWQQLTGALIGHMTNVRRVFNELIGDDESETQEESLSEQWRELWQDALQEDDTTPVLAHLSEDDRKQVLTLIADFRKELDKRTIGPRGRQVLDHLMPHLLRDVCTREDAAVTLSRITALLVGIVTRTTYLELLSEFPAALKHLISLCAASPMIASQLARYPLLLDELLDPNTLYQPTATDAYRDELRQYLLRVPEDDEEQQLEALRQFKQAQLLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWVQMVARYGKPNHLNEREGRGFAVVGYGKLGGWELGYSSDLDLIFLHDCPMDAMTDGEREIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGAAGMLVTSAEAFADYQKNEAWTWEHQALVRARVVYGDPQLTAHFDAVRREIMTLPREGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIEFITQYLVLRYAHEKPKLTRWSDNVRILELLAQNDIMEEQEAMALTRAYTTLRDELHHLALQELPGHVPEDCFTAEREQVRVSWQKWLVEE", "output": "Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell."}]}
+{"id": "function_test_2232", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKSVRYLIGLFAFIACYYLLPISTRLLWQPDETRYAEISREMLASGDWIVPHLLGLRYFEKPIAGYWINSIGQWLFGANNFGVRAGVIFATLLTAALVTWFTLRLWRDKRLALLAAVIYLSLFIVYAIGTYAVLDPFIAFWLVAGMCSFWLAMQAQTWKGKSAGFLLLGITCGMGVMTKGFLALAVPVLSVLPWVATQKRWKDLFIYGWLAVISCVLTVLPWGLAIAQREPDFWHYFFWVEHIQRFAMDDAQHRAPFWYYLPVIIAGSLPWLGLLPGALYAGWKNRKHSATVYLLSWTIMPLLFFSVAKGKLPTYILSCFAPLAMLMAHYALLAAKNNPLALRINGWINIAFGVTGIIATFVVSPWGPMNTPVWQTFESYKVFCAWSIFSLWAFFGWYTLTNVEKTWSFAALCPLGLALLVGFSIPDRVMEGKHPQFFVEMTQESLQPSRYILTDSVGVAAGLAWSLQRDDIIMYRQTGELKYGLNYPDAKGRFVSGDEFANWLNQHRQEGIITLVLSVDRDEDINSLAIPPADAIDRQERLVLIQYRPK", "output": "Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides."}]}
+{"id": "function_test_2233", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAALVKQLGLADYASTYEAMQAFTKARTSETLDEIWVLEHPPVFTLGLAGDAGNLHSPSNQISLVQVDRGGEITYHGPGQIVVYLLLDLRRLGIFVKELVSRIEQAVIDTLADFGVQAERHPGAPGIYVSQQSRVPPEWVGAKIAALGLKVSKSCSYHGLALNVATDLEAFKRIHPCGYEGLKTVDMQTLGIKDNMDTISLRLLQHLQKQLIPS", "output": "Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate."}]}
+{"id": "function_test_2234", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSRTFYDKLWDDHVIYSEEDGTATIYIDRQLLHEVTSPQAFEGLNLAGRPVWRISANLAVSDHNVPTTDRSEGITDPISKLQVDTLDQNCDAFGITQYKMNDTRQGIVHVIGPEQGATLPGMTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLLMKKSKNMLVKVDGRLQPGSTAKDIVLAVIGKIGTAGGTGYTIEFAGEAIRNLSMEGRMTLCNMAIEAGARASLVAVDETTIEYIQGRPYAPKGAAMLQALQYWRTLHSDPDAKFDAVVELRAEEIAPQVTWGTSPEMVLAISDRVPDPEKERDSNKRSAMERALQYMNLNPNTPISSIAVDKVFIGSCTNSRIEDIRAAAKVIDRLGKKVAANVKLALVVPGSGLVKAQAEREGLDRIFKAAGFEWREPGCSMCLAMNADRLEPGERCASTSNRNFEGRQGNGGRTHLVSPAMAAAAAIEGHFVDVRKIS", "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."}]}
+{"id": "function_test_2235", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRVFNFSAGPAALPEEVLRQAADEMLDWHGSGMSVMEMSHRGKEFMSIHEAALADLRELLDVPASHRILFLQGGGIAENAIVPMNLLGSRKTADFVVTGSWSQKSFNEAKKYGTPHLAASGKTADGFTRAPARAEWQLSDDPAYVHLCTNETIDGVETFEIPDLGDVPLVADVSSHILSRPMDVAKYGVLFGGAQKNIGMAGVTVVIVREDLLDRALSICPSAFEWKTVAANNSLYNTPPTYAIYIAGLVFQWLKRQGGLEAIEARNIEKAKLLYDTIDASGFYLNKVEPAVRSRMNVPFFLADETRNEDFLAGAKARGLLQLKGHKSVGGMRASIYNAVPLEGVKALVEYMKDFEQRGA", "output": "Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine."}]}
+{"id": "function_test_2236", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNQKYSVTVPELGITFSTGSIAQLANGAVNVQVGETNVFVTACVAQTTKPGQDWFPLTVDYREKYAAAGRFPGGYFKREGRPSEKEILTSRLCDRPCRPLFPEGFLNEVQIIGQLFSADLVNESDISMVNGASAALAISDIPWNGPIAAVRVAEIEGKFVANPTIDQMFASSLDLIYVGNEKDMLMIEGSADQIPEERFIEALAFGHESIQPILKAIKELVAQCGKPKGTFPLVGATPEARTIIERVVPTERLIEAIFGKEKAVRANAVKLLKEEAKAALTAELGEGKFTDVDLNVVFEDLQYKAYRKTVLERGVRADGRGQKDIRPLQAQVGVLPRVHGSAMFQRGDTQNIALTTLGPTKDAQDLDALTGGVKSKSFLLHYNFPPFSVGETGRFTGPGRREIGHGALAERSLVPVLPPEDVFPYSIRVVSEIMASNGSTSMASICGGCLSLMDAGVPIIAPVAGISCGLMTQNASDGSIEKWVTITDILGEEDHFGDMDFKLAGTSKGITGFQLDLKINGLPFEIAKTAIMQARDARMEILKVMLGSLPAPRADLSKYAPRIQTIQIDPEKIGLLIGPGGKTIRRITETTGAQIDIAEDDSGKVFVYSNNAEAMNRAIQEIDSLCGGGGPGGSKGPAIEVGKIYTGRVTGVKEFGCFVECTPGNEGLCHVSELADFRVRRTEDVVKMGDSITVKCIGIDERSGKVRLSRKAAMKELEAQKQSSEAAPAQ", "output": "Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction."}]}
+{"id": "function_test_2237", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSAPTFAEDPVTQRPALQSADFRLTVRQNPERARVAGGKEKERKAVDPPPIIQLKIDESKDPGQNYLQSPFYFMCCTLYNATEDTPATTAQSTALAGTLVSSLHRLKDTDNMEGGFFVFGDLSVKIEGEFRLKFNLFEMREVKRCGGSRDEVVYIKSILSKPFTVLPPKNFPGMTESTWLSRSFADQGVKLRIRKEARTLLKRPLNRAEPDYPAPPTQPRTPERSGASSQQMVAAYQTNRDYPFYNGPDAKRPRSSVDMSGRGLYEGDARYSYPPHAANPYQGQTYQQGMMQGYPTAGAGVSDYAIRQAQQGSTPTPFGSADESIGSIRSPGAGGYIGQPRYQSYSGAQMPYNLASSTQMSQMGESTPGRTGQAANMGGIVSGQSFSQSAGHMQSPSQVPPAWG", "output": "Component of the RYP2-RYP3 heterodimeric complex that plays a dual role in activating genes associated with spore maturation and repressing certain development-associated genes (By similarity). The complex binds DNA through the DNA-binding domain of vosA that recognizes an 11-nucleotide consensus sequence 5'-CTGGCCGCGGC-3' consisting of two motifs in the promoters of key developmental regulatory genes (By similarity). Required for viable spore production and regulation of sporulation in response to temperature and for the switch to yeast-form in the presence of host cells ."}]}
+{"id": "function_test_2238", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTQSVCILGVTGSIGRSTLKILGQHPDKYSVFAVSAHSRISELVEICKQFRPKVVVVPEQKIVELKTLFAQQNISDIDVLAGQEGLVDIASHTDVDIVMAAIVGAAGLLPTLAAVKAGKRVLLANKEALVMSGEIMMQAARDHQALLLPVDSEHNAIFQSLPHNYLQADRTGQPQLGVSKILLTASGGPFLNHSLEQLTHVTPQQACKHPNWSMGQKISVDSATLMNKGLELIEACHLFSISEHFVTVVVHPQSIIHSMVQYVDGSTLAQMGNPDMCTPIAHALAWPERLQTNVPALDLFEYSQLNFQAPDTQKFPALNLARQAMRAGGLAPTILNAANEIAVEAFLMERIGFTSIPQVVEHTLEKLENAAAESIECILDKDKVARSVAQQYISSIGG", "output": "Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)."}]}
+{"id": "function_test_2239", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MENKKVIVGISGGVDSSVSALLLKQQGYDVTGVFMKNWEEDDTDEFCSAEQDIADAQAVCDSIGIPFKKINFAAEYWDNVFEHFLIEYKAGRTPNPDILCNKEIKFKAFLSYVHLLGGDYIATGHYAQTRLAADGSVQLVKGLDDNKDQTYFLYTLGQEQLRQTIFPIGNIEKSKVREIAKENNLVTFDKKDSTGICFIGERKFKEFLSKYLPAQKGEIHDENGIKIGMHDGLMYYTIGQRQGLGIGGVKDRPEVPWFAAKKDLENNVLIAVQGHDHPLLFKQSLQAIELSWVAGMAPADKFRCAAKVRYRQKDQSCEVEVNQDGSVNVTFDQPQRAITPGQSVVFYIDDVCLGGGVII", "output": "Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34."}]}
+{"id": "function_test_2240", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MYENKMNLEFVSKSQNEAFARVAVAAFIAQLDPTIDEISDVKTAVSEAVTNSIIHGYENKEDGIIKIEVEICDGEVTIEITDNGKGIEDIPKVMEPLYTSRPDLERSGMGFTVMETFMDGLLVESEKEKGTRVRMKKKFNILS", "output": "Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition."}]}
+{"id": "function_test_2241", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "DDCLGMFSSCDPDNDKCCEGRKCNRKDKWCKYVL", "output": "Spider venom neurotoxin that blocks voltage-gated sodium channels Nav1.3/SCN3A and Nav1.8/SCN10A in human (IC(50)=2 uM and IC(50)=4 uM, respectively) and rat (IC(50)=2 uM and IC(50)=2.5 uM, respectively)."}]}
+{"id": "function_test_2242", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIFSQGSSPIKGDFSKIKFSIASPESILAHSRGEVLKPETINYRTFKPERDGLMCEKIFGPTKDWECYCGKYKRVRYKGIICDRCGVEVTTKNVRRERMGHISLAVPVVHTWFFRSVPSKIGALLDLSTKELERIIYYEVYVVINPGEPGEKQGIKKFDRLTEEQYFQIITEYEDNQDLEDNDPAKFVAKMGGEAIHTLLKGLNLDEIAVNLRKVLKESGSEQKRADALKRLKVVESFRKSYEPQKRTRKKSTGLFPEEDSPELYIYEGNKPEYMVMEVVPVIPPELRPLVPLEGGRFATSDLNDLYRRVIIRNNRLKKLIDIRAPEVILRNEKRMLQEAVDALFDNSRKANAVKTGESNRPLKSLSDALKGKQGRFRQNLLGKRVDYSGRSVIVVGPELQLHQCGLPKSMAIELFQPFVIRRLVERGIAKSVKSAKKLIDKKDPVVWDVLEKVIDGRPVLLNRAPTLHRLGIQAFQPTLIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSQEAQLEASLLMLSSHNLILPQSGKPVTVPSQDMVLGMYYLTKARFGDVGQGQLFYSMEEVIIAYNEERAGLHAQIFVKYDGKVDQVSDPVRLVDTLVPEEQAERRAWLKSQIEQKKVLVTTVGRVIFNQHMPEKIGFINKLINKKVAKELIAHLSSQVGNVETAQFLDNIKAVGFGYAMRGGLSIGLSDAIVPETKVKHIKNAQRDSAKVVKEYNRGTLTDNERYNQIVDVWQKTSNLVADESYQKLKNDRDGFNPLYMMLDSGARGSREQVRQLTGMRGLIARPQKSMSGQPGEIIENPIISNLKEGLTVLEYFISTHGARKGLSDTSLKTADAGYLTRRLHDVAQDVIVTIDDCGTTRGLHVERNIEEETSGQIKFREKIKGRVAARDIVDVINDKVVVKAGEIITDELAAAIQDNIGVEEAEIRSVLTCESKVGICSKCYGTNLSVHKLVEMGEAVGVIAAQSIGEPGTQLTLRTFHQGGAAQGGISETETKAFYEGQVELEDVKSVEHSIITEDGIEETRQIVIQKNGKLNIIDPDSGKVLKRYVVPHGAHINVENGQMVRKDQVLFSSEPNSTQILAEMPGFAKFIDIEKGVTYKEEVDPQTGFAQHTIINWRSKLRASETREPRIAIVSESGEIKKTYPVPIKSNLYVEDGQKLNPGDTIAKVPRNLDRVGGDITAGLPKVTELFEARIPTDPAIVSEIDGYVSFGSQRRSSKEIKVKNDFGEEKTYYVQVGKHVLATEGDEVKAGDPLTDGAVSPQDILRIQGPNAVQQYLVNEIQKVYQINAGVEINDKHLEVIVRQMLQKVRVEEAGDTNLLPGDLIDRGTFIEANEAVAEKVRVIDRGDAPPRIQEGQLYKQRDITKLNRELRRNSKSLITIEPALQATSHPVLLGITSAALQTESVISAASFQETTKVLTDAAVAGKVDHLAGLKENVIVGKLIPAGTGLRKYRSIRLQSNEPEEVDVIESASTGDAEEEN", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_2243", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLRALKTHVEAPIVVATRAASTNAEKLEEIRERLAKGPNFQDFVQNPDNTRSEWEQYDGKLRREKGEEQRLRLPPWLKTTIPVGKNYAKIKAQMRELKLSTVCEEARCPNIGECWGGGEHGTQTATIMLMGDTCTRGCRFCSVKTARKPPPLDVNEPVNTATAIASWGLDYIVLTSVDRDDLPDGGSKHIAETVREIKARNSNIFVECLVPDFRGNLECVETIANSGLDVYAHNIETVEKLTPYVRDRRAHYRQTLQVLTEAKRFNPNLITKSSIMLGLGETDEEIENTLKDLREAGVDCVTLGQYMQPTNKHLKVIEYVTPEKFKHWEERGNELGFLYTASGPLVRSSYKAGEFFITSILENRKKRQNATEVPKEQ", "output": "Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives."}]}
+{"id": "function_test_2244", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSASTRNKHSKIHGNEKLDISNDEFDRIRDALKNEEFRKLFFDYVDEIQDPENRKIYEEEITQLEKERGVDVTFIHPQPGFVIKTSIDGELKCFINIASCKVVERPNNEVSVNSQTGQKGLSWSIPLAQIPPRDDLDANNKLCKVYDVVFHPDALHLAKRNAQFRQCLIDTALDGVEREYHVNLDRANLKFPKLDYKGMARPSVLRTLSKNPTAEEKEPHPLEHMYPKKPEADAGQSKVLPMKTKVTAVPKFAVPKYCIKHSHDVDMAEYTDELDAKLQVTVPRALVVEIELPLLSSTADCHLDVTEKSVYLLSEKQGAKYKLKVDLPYTVNDKAGNARFDTDHRCLRITLPVVRSTPREERNLHDTVRNLSREDSGVELNSNGESPVEDEELVVELSEHNQENDSNAFPPTAVVSPRSFLKSNLHYLLPAQFNCNILDNVIVFVLHVTNVQPDSVQTLQQARSLHLQFASMGTGYYPTHYAFLMQLPDGVQPELRIDQVEVDTGDENVVLRLTMNEHCMLLPSYLAGTDSNDLKEYPVFGHQNNNNEKETEVEVAEMEKCDLVSEKSLQINMDHNDVEHALEVTIEPQENEAPLDSLELLHEHQQELQQLHHQKKLNKKQRKRNKKQRSLSESACEDLKLAQEHHEQPMDTLKLPHRKQRSYSECNESSLGSSCVQRGILKRFSRYGPHPSISDSCSSIDDCSSTYSCSVDAAGTGFSQSFGSIPEERGGDEAGLSESCKKTVRFNDHIMKQVFRLDSSILGQRKKNQKRRDCKLRAQQRRLSEGDSADYVEVDSTHGSGDQPAHKTAANAQYFKQHNNNHPHVKDNKKQSLHDSGLDLTNGSINNKNNHSNENATKRNEADAKNTMMFEMDDVDEEAQDAANI", "output": "Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment."}]}
+{"id": "function_test_2245", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPDRPVRTRIAPSPTGMMHIGTARTALFNWLYARHTGGKFLLRIEDTDRERSTDEAVKVIFDGLKWLGLDADEPPVFQFARADRHREAAETLLARGGAYRDYMTPEELEAEREVARAEGRVVRSPWRDASPNDAPDRPFVVRLKAPQEGETVIQDAVKGEVRFQNKQLDDLILLRTDGTPTYNLAVVVDDHDMGVTHVIRGDDHLNNAARQTLIYQGLGWEVPVWAHLPLIHGPDGAKLSKRHGAQAVSEFDSMGYLPETMRNYLAKLGWGHGDDEIFSDEQAIAWFDINDVVSAPARLDWAKLNHLNNHYIRQAEPARLAELVKTVLASRDWPLEAGDMAVIERTIPFVRDGAKTTLELADNVVFALKRRPLELPEKTRTQMTEELRGRLSRLREALAAVEYWDVPSLEAALRAFAEAEGVGLGKFGPQLRAVLSGGAPAPDLAGAMVALTRDESLGRLDDALSPSA", "output": "Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)."}]}
+{"id": "function_test_2246", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSCPVIELTQQLIRRPSLSPDDAGCQALMIERLRKIGFTIEHMDFGDTQNFWAWRGRGETLAFAGHTDVVPAGDVDRWINPPFEPTIRDGMLFGRGAADMKGSLAAMVVAAERFVAQHPHHRGRLAFLITSDEEASAKNGTVKVVEALMARHERLDYCLVGEPSSTEIVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPFLNELVAIEWDRGNDFFPATSMQVANIQAGTGSNNVIPGELFVQFNFRFSTELTDEMIKERVHALLEKHQLRYTVDWWLSGQPFLTARGKLVDAVVNAIEHYNEIKPQLLTTGGTSDGRFIARMGAQVVELGPVNATIHKINECVNAADLQLLARMYQRIMEQLVA", "output": "Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls."}]}
+{"id": "function_test_2247", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MQLNSTEISDLIKQRIEKFNVVTEARNEGTIVSVSDGIINIHGLADVMQGEMIELPGGRYALALNLNRDSVGAVVMGPYADLQEGMKVTGTGRILEVPVGPELLGRVVNTLGEPIDGKGPIEAKLTSPVEVIAPGVIDRKSVDQPVQTGYKSVDSMIPIGRGQRELIIGDRQTGKTAMAIDAIINQKDSGIFSIYVAIGQKASTIANVVRKLEEHGALANTIVVVASASESAALQYLAPYSGCAMGEYFRDRGEDALIVYDDLSKQAVAYRQISLLLKRPPGREAFPGDVFYLHSRLLERAARVSEAYVERFTNGEVTGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLQTELFTAGVRPAVDPGISVSRVGGSAQTKIIKKLSGGIRTALAQYRELAAFAQFSSDLDDATKKQLDHGEKVTELMKQKQYAPMSVFDQALVIFAAEKGYLKDVELAKLADFEEALLSYARGQFADLAKEIDTSGAWNNEIEAQFVKLVEDFKATQTW", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit."}]}
+{"id": "function_test_2248", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTEKKYIVALDQGTTSSRAVVMDHDANIVSVSQREFEQIYPKPGWVEHDPMEIWASQSSTLVEVLAKADISSDQIAAIGITNQRETAIVWERETGKPIYNAIVWQCRRTADICEQLKRDGLEDYIRDNTGLVVDPYFSGTKVKWILDHVEGSRERAKRGELLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHDLDWDDKMLDVLDIPRAMLPQVRKSSEVYGQTNIGGKGGTRIPIAGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNTGEKAVKSENGLLTTIACGPSGEVNYALEGAVFMAGASIQWLRDEMKLISDAFDSEYFATKVKDTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNSNHIIRATLESIAYQTRDVLEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGLAVGYWQNLDELQEKAVIEREFRPGIETTERNYRYSGWKKAVKRAMAWEEHDK", "output": "Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate."}]}
+{"id": "function_test_2249", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKKAGIIHLGCSKNQVDTEILMGFLKELGYTFTPYLGEADLVLVNTCAFIKPAWQEAEENINFLKEYKENNKNLKIVVTGCYVERFEKELEDRYPFVDLFIGPGEYDKFVSLITSNGERKIHSSPASSFMYTHKMPRVLISPNFWVYVKISEGCNNFCSYCTIPFIRGRLRSRSIDDIIKEVEILVQKGVKEINLIAQDTTRYGEDLYGKSALVDLLKSIENIKGDFYVRILYSYPSRVTKDLINFIKVSEKVVPYFDIPIQHVNDEILKKMNRSYKKDDIIRVWSTIRENFEDAVIRTTVMVGFPGETEENFEELIAFIKAYPFDRLGAFTYYNEEGTISKNFDGQIDEDEKIRRYDILMSTQKEISKKLNAKLLGREFDVIIENEKGKYFIGRSWREAPEVDGVIMIPKEGSRSISIGDRVRVKIKKYRAYDLLGELV", "output": "Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12."}]}
+{"id": "function_test_2250", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MHALEQKILTEGIVLSDQVLKVDAFLNHQIDPVLMQQIGKEFAARFKDAGITKIITIEASGIAPAIMAGLELGVPVIFARKYQSLTLKDDLYRAKVFSFTKQTESTIAISNKHINSSDKALVIDDFLANGQAALGLIDLIHQANAEVVGVGIVIEKSFQPGRDLLLEKGYRVESLARVQSLADGTVTFVKE", "output": "Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis."}]}
+{"id": "function_test_2251", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTKNNEAGWNLDHSYTTLPQSFYTEIPPTPVSSPELVKLNHSLAISLGFNPEELKKEAEIAIFAGNALPEGAHPLAQAYAGHQFGHFNMLGDGRALLIGEQMTPSGKRFDIQLKGSGPTPYSRRGDGRAALGPMLREYIISEAMYALDIPTTRSLAVVTTGEPTYRETKLPGAILTRVASSHIRVGTFQYAAARGSIEDLQSLADYTIKRHYPEIEAHENRYTALLQEVIKKQASLIAKWQLVGFIHGVMNTDNITISGETIDYGPCAFMDNYDQGTVFSSIDTQGRYAYGNQPYMAAWDLARLAESLIPILHEDEEEALKIAQDEISKFSVQYEKQWFLGMKKKLGLFSNEEQDQSLIEQLLKMMEKFKADYTNTFRSLTLNTIENTALFESPEFKEWYKLWQSRLEKQEESKENAYEMMKNNNPSIIPRNHRVEEALEAAVTNGDYSVMEKLLEALSNPYAYATEQEEYCVPPAPTNRPYRTFCGT", "output": "Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation)."}]}
+{"id": "function_test_2252", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MHILVVSVNYRTAPVEFREKLTFQAAELERAMTTLQNQKSVLENVIVSTCNRTEIYAVVDQLHTGRYYIKKFLADWFQLEIEEVAPYLTIFEQDGAIDHLFRVTCGLDSMVVGETQILGQIKDSFLEAQQVKATGTIFNELFKQVITLAKRAHSETTIGESAMSVSYAAVELGKKIFGELTDCHVLILGAGKMGELALQNLYGSGARKVTVMNRTLSKAEIMAEKYMGHAKPLSELQCALLEADILISSTGASDYVITKEMMTKVEKMRSGRPLFMVDIAVPRDIDPAIDELEGSFLYDIDDLQGVVEANRAERLKEAEKIQFMIEEEIVLFKTWLSTLGVVPLISALRDKALAIQSETMESLERKIPNLSDRERKVISKHTKSIINQLLKDPILVAKEIAAEEGADEKLALFAKIFDLEMEDVESRAEEVEHKRVWTPSVPSL", "output": "Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA)."}]}
+{"id": "function_test_2253", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNNDVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWLVLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVETKEEAEQAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDNVDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAPVEADARRYLEWGATFVAVGSDLGVFRSATQKLADTFKK", "output": "Catalyzes the reversible retro-aldol cleavage of both 5-keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde."}]}
+{"id": "function_test_2254", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEATVNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLESAMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAVKSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQEFDVIGTVNALEQRLEDIITSMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGVRKDRLDNNDMIDQLEARIRAKASQLDEARRIDVQQVEK", "output": "Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate."}]}
+{"id": "function_test_2255", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MFLAQEIIRKKRDGHALSDDEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGPIVDKHSTGGVGDVTSLMLGPMVAACGGYIPMISGRGLGHTGGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSLAPADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGARVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGKLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPTDFVENYAKYLPTAMLTKAVYADTEGFVSEMDTRALGMAVVAMGGGRRQASDTIDYSVGFTDMARLGDQVDGQRPLAVIHAKDENSWQEAAKAVKAAIKLADKAPESTPTVYRRISE", "output": "The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis."}]}
+{"id": "function_test_2256", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDQKQIEEIVRSVMASMGQAAPAPSEAKCATTTCAAPVTSESCALDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPDVQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR", "output": "Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of external vitamin B12."}]}
+{"id": "function_test_2257", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKNIAIIGASGYTGAQITSLINAEMGLSIQGLYVSENSLDKGKALAELYPTYSHIHLCLSPLNDDAKAAIVEQADAVVLATDHVVSLHLAAWFYQQGLAVFDLSGAYRFEALDKYPKWYGFTHEYPQVLADAVYGLAEWNAEKIATSKMIAVPGCYPTASLTALKPLADLLTDVMPVINAVSGVTGAGRKAQLHTSFCEVSLTPYGVLGHRHQPEIATQLGQEVIFTPHLGNFKRGILATITVQLAQGTTAKDIEAAYQCYDNAPLVTVKQNQFPKVDDVVQTPNCLIGWKFDPETNYLVVTSAIDNLMKGAASQALQCIKIHFNELLK", "output": "Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde."}]}
+{"id": "function_test_2258", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNKKTRIAITGPIGRMGRMLIKEIQNNKQSHLTVAVVQKKHQLIGQDIGRIIGIGEIGVLISDELNIKKNDFDVLIDFTRPAGTLEYLKYCNKFKKNIVIGTTGFSKEEIDIIKSYSQKIAIIIASNFSIGINLLFQLIKKTTQIIGKDSDINILEYHHRNKIDAPSGTALEIGEVISKVMNWNLNQDSIYYQKGITGIRDAKKIGFSIVRAGNIVGKHTVMFSSCDEEIKITHTASNRMSFARGAIQSALWIHKKNTGLFDMTDVLSL", "output": "Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate."}]}
+{"id": "function_test_2259", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNYTLTKADSDNNNKKYPKQTIESVSDPLEEYLKKNIFMGKITQLLHKLVNWGRKNSLWPYNFGLSCCYVEMVSAFTSVHDVARFGSEVLRASPRQADVMVIAGTPFIKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFLPVDIYIPGCPPRPEAYMQALILLQKLINEERRPLSWVIGEQGVYHKKMPSERVQKRSKRINIINLSTSEKI", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_2260", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSISVGLGSYLLVGAMLFCLGLYGVFVKRNIIAILMSIELMLNAVNINFIAFSRFAPWANPGTNPLIGQVAAIFVIVVAAAEIAVGLALVIAIYRNRRTTNVDEFNWLKW", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_2261", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGWQRPDGRQSHQLRPISFERGFTRFAAGSVLTRCGQTQVLCNVTVRPGVPKFLEGRGQGWLTAEYRMLPAATPQRQEREMLKLSGRTQEIQRLIGRSLRAALDFDLLGERTLVVDADVLQADAGTRTTAITGSFVALADAIDQLLQAGELQRSPIRNYVAAVSVGLLEGEPFLDLSYQEDVAASVDFNVVMTESLQILELQGTAEGESFSRTQLNQILDVAEVGIRELIAAQKSVLGQ", "output": "Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation."}]}
+{"id": "function_test_2262", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQQYLDLCKHILNNGIKKEDRTGTGTISTFGYQMRFDLQKGFPLLTTKKLHLKSIIHELLWFISGNTNIKYLKDNGVSIWDEWADENGNLGPVYGHQWRSWDTADGRSIDQLKGVIDQIKNNPDSRRLIVSSWNVGEIEKMALPPCHCFYQFYVVNGTLSCMLYQRSADVFIGVPFNIASYALFTMMIAQSCGLRAGEFVHTLGDAHIYLNHVEQVKLQLSRDPRPLPKMNINPDIKDLFQFKYSDFTLTDYDPHPHIKGAVAV", "output": "Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis."}]}
+{"id": "function_test_2263", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVILSKVAAVAVGLSTVASALPTGPSHSPHARRGFTINQITRQTARVGPKTASFPAIYSRALAKYGGTVPAHLKSAVASGHGTVVTSPEPNDIEYLTPVNIGGTTLNLDFDTGSADLWVFSEELPKSEQTGHDVYKPSGNASKIAGASWDISYGDGSSASGDVYQDTVTVGGVTAQGQAVEAASKISDQFVQDKNNDGLLGLAFSSINTVKPKPQTTFFDTVKDQLDAPLFAVTLKYHAPGSYDFGFIDKSKFTGELAYADVDDSQGFWQFTADGYSVGKGDAQKAPITGIADTGTTLVMLDDEIVDAYYKQVQGAKNDASAGGYVFPCETELPEFTVVIGSYNAVIPGKHINYAPLQEGSSTCVGGIQSNSGLGLSILGDVFLKSQYVVFDSQGPRLGFAAQA", "output": "Secreted aspartic endopeptidase that allows assimilation of proteinaceous substrates. The scissile peptide bond is attacked by a nucleophilic water molecule activated by two aspartic residues in the active site. Shows a broad primary substrate specificity. Favors hydrophobic residues at the P1 and P1' positions, but also accepts a lysine residue in the P1 position, leading to the activation of trypsinogen and chymotrypsinogen A."}]}
+{"id": "function_test_2264", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGKRLLDKLWERHVVATNENGLDLLYIDLHLVHEVTSPQAFEGLRLTNRTVRRPDLTFATMDHNIPTKDVWNITDRIAKQQLDTLRENCKQFQVPLADIGDEEQGIVHVIGPELGLTQPGKTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLWQRKPKAMGIELKGKLQKGVYAKDIILHLLSKYGVAVGTGYVMEFYGETIQAMEMEERMTLCNMAIEGGAKAGIIAPDEKTVAYVKGRKYAPRDYETFEKKWFELYTDADAIYDLHISIDVTDLAPYVTWGTNPSMGVRIDEKLPEKHDVNDERAFSYMGLSPGQSTYDIPVQHVFIGSCTNSRLSDLEIAAAVVKGRKVKEGVRALVVPGSKRVRDAAMQKGLHHIFEEAGFEWREPGCSMCLGMNPDQVPEGEHCASTSNRNFEGRQGKGARTHLVSPAMAAAAALYGHFVDTRKESYDGAISYS", "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."}]}
+{"id": "function_test_2265", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFNVTKKSIEWGGETLTLETGKVARQADGSVIATLGETSVMANVTFAKAAKPGQDFFPLTVHYQERYYAAGKVPGGFFKREARPSEKETLTSRLIDRPIRPLFVDGFKNEVLLIVTVLSHDLVNEPDIVAMIAASAALTISGVPFMGPIGAARVGFAGGEYVLNPDVDDMQKLRENPEQRLDLVIAGTKDAVMMVESEAYELSEAEMLGAVKFGHEAMQPVIDMIIDFAEEAAHEPFDFSPPDYAALYAKVKSLGEAQMRAAFAIREKQDRVNAIDAARAAIKAQLSEAELADENLGTAFKKLESSILRGDIINGGARIDGRDTKTVRPIISETSVLPRTHGSALFTRGETQALVVTTLGTGEDEQIIDALHGNSRSNFLLHYNFPPYSVGEVGRFGPPGRREIGHGKLAWRALQAVLPAATDFPYTIRVVSEITESNGSSSMASVCGGSLSMMDAGVPLKAPVAGVAMGLILEDDGKWAVLTDILGDEDHLGDMDFKVAGTENGITSLQMDIKVAGITPEIMEQALAQAKDGRMHILGEMSKALSSANSFSAYAPKIETLTIPTDKIREVIGSGGKVIREIVETSGAKVDINDDGVIKIASNDQAAIKKAYDMIWSIVAEPEEGQIYTGKVVKLVDFGAFVNFFGKRDGLVHVSQIANKRLTHPNEVLKEGQEVKVKLLGFDERGKVRLGMKMVDQETGQEIQPEKKEREEAGEA", "output": "Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction."}]}
+{"id": "function_test_2266", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRIAIYPGSFDPVTYAHLDIARRATRIFDRVIMAVFDRPQKRLLFSTAERLQLLQAVTADLVNVEATSYEMLTVEFARQVGACAIVRGLRAGSDFEAEFQMAQVNQTIDPNIEVVVLMAGRQFAHISSTAVREMASLGRDPVEFTPPVVVAALREKFAQRG", "output": "Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate."}]}
+{"id": "function_test_2267", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRDRFLRACRRQPVDRTPIWLMRQAGRYMPEYRAIRERYGFLQMVKTPEVAAEVTLQPVQAFGVDAAIIFADILPPLEGLGLQLTYEKGEGPVIHNPIRSPHDVSVLRSCDPRETVAYTLAALQLVKRELNGLPLIGFSGAPFTLASYAIEGGGSREYRLTKRFMYEQPAAWHDLMERLSRLVADYLIAQIEAGADAVQIFDSWAGALSPADYRAYVLRHTQALVQTIRARLGDVTPPIIYFGTDMAGLAGEVRQIGADVLGVDWRIDLDVAWAQYGFNHAVQGNLDPMTLFAPPSIIAARARDILERAGGRPGHIFNLGHGILTETPVDHVRYLVEFVQSYPLPATAPVLQEVV", "output": "Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III."}]}
+{"id": "function_test_2268", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "METLDAIQLPYLGVVGASLIVILGIILLFPLGSDPFITINQHPRDLFQTKAKQQFEYNAAALLNEGLQTGHSAFRLVTNMVTYLILKDQYAEEIKNDSRFGAHEAVDPVLLVDLPGLESMFQGSLHNQVPPMAVRALNKELVHLTPSLSEEAMNCLQTRWTDSTEWHGVSIPETVLALIAQMTTRALLGPELCRNPEWLDIAKSFTTNRAIAVAAVQSWPSFLQPVIHWFLPPCRALRRQIQCARNIILPALERERRAYCSDQPTKREFSNLVFIDQYAKGARYDATMAQLRIIAVAFQTTSDLVEKVIARLCKHPELIEPLREEVVSVVGNRGLHRHSLRKLTLMESVMKETQRLEPAVIIGMFRLAKEKVTLKDGTVVPKGTNIAFANDLRFDPEMYLEPETFDGYRFQRMREDPAKIDLAPFTKTRMSHLAFGHGKHACPGRFLACDEAKLILCHILLNYDIRAVEGSPPELRARGMFVQLDPGAMMSVRRRRGTETAPHG", "output": "Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of fumitremorgins, indole alkaloids that carry not only intriguing chemical structures, but also interesting biological and pharmacological activities . The biosynthesis of fumitremorgin-type alkaloids begins by condensation of the two amino acids L-tryptophan and L-proline to brevianamide F, catalyzed by the non-ribosomal peptide synthetase ftmA . Brevianamide F is then prenylated by the prenyltransferase ftmPT1/ftmB in the presence of dimethylallyl diphosphate, resulting in the formation of tryprostatin B . The three cytochrome P450 monooxygenases, ftmP450-1/ftmC, ftmP450-2/ftmE and ftmP450-3/FtmG, are responsible for the conversion of tryprostatin B to 6-hydroxytryprostatin B, tryprostatin A to fumitremorgin C and fumitremorgin C to 12,13-dihydroxyfumitremorgin C, respectively . The putative methyltransferase ftmMT/ftmD is expected for the conversion of 6-hydroxytryprostatin B to tryprostatin A (Probable). FtmPT2/FtmH catalyzes the prenylation of 12,13-dihydroxyfumitre-morgin C in the presence of dimethylallyl diphosphate, resulting in the formation of fumitremorgin B . Fumitremorgin B is further converted to verruculogen by ftmOx1/ftmF via the insertion of an endoperoxide bond between the two prenyl moieties . In some fungal species, verruculogen is further converted to fumitremorgin A, but the enzymes involved in this step have not been identified yet (Probable)."}]}
+{"id": "function_test_2269", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "GPMGPSGPRGIPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGIPGTAGIPGMKGHRGFSGIDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGIPGERGRPGPPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPSGAPGPKGNSGEPGAPGNKGDAGAKGEPGPAGIQGPPGPAGEEGKRGARGEPGPTGIPGPPGERGFPGSDGVAGPKGPVGERGSPGPAGPKGSPGEAGRPGEAGIPGAKGITGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGAPGKDGEAGAPGATGPAGPAGERGEQGPAGSPGFQGIPGPAGPPGESGKPGEQGIPGDIGAPGPSGARGERGFPGERGVQGPPGPAGPRGSNGAPGNDGAKGDAGAPGAPGSQGAPGIQGMPGERGAAGIPGPKGDRGDAGPKGADGSPGKDGPRGITGPIGPPGPAGAPGDKGESGPNGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPTGAPGPIGNVGAPGPKGSPGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKGETGPAGRPGEIGPPGPPGPSGEKGSPGADGPAGAPGTPGPQGIGGQRGVVGIPGQRGFPGIPGPSGEPGKQGPSGPNGERGPPGPMGPPGIAGPPGESGREGSPGAEGSPGRDGSPGPKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPIGPVGARGPTGPQGPRGDKGETGEQGDRGFSGIQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGINGIPGPIGPPGPRTGDAGPVGPPGPPGPPGPPGPP", "output": "Type I collagen is a member of group I collagen (fibrillar forming collagen)."}]}
+{"id": "function_test_2270", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "GVPCGESCVYIPCFTGIINCSCRDKVCYNN", "output": "Probably participates in a plant defense mechanism (By similarity). Has cytotoxic activity against HUVEC cells (LC(50)= 2.17 uM) and various cancer cells including HeLa (LC(50)= 3.05 uM), MCF-7 and K562 . Displays very weak hemolytic activity . Binds to and induces leakage in phospholipd membranes, particularly ones containing 1-palmitoyl-2-oleophosphatidylethanolamine (POPE) ."}]}
+{"id": "function_test_2271", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSLSVTRENFDEWMVPVYVPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPALREALNEQANRFWHTGNGYTNEPALRLAKKLIDATFAERVFFCNSGAEANEAALKLARKYAHDRVGNHKSGIVAFKNAFHGRTLFTVSAGGQPTYSQDFAPLPPDIRHAAYNDLNSASALIDDNTCAVIVEPVQGEGGVIPATKAFLQGLRELCDRHQALLIFDEVQTGVGRTGELYAYMHYGVTPDILTTAKALGGGFPIGAMLTTQDYASVMTPGTHGTTYGGNPLATAVAGKVLDIINTPEMQNGVRQRHDAFIERLNTINVRFGMFSEIRGLGLLLGCVLQTEFAGKAKLIAQEAAKAGVMVLIAGGDVVRFAPALNVSDEEIATGLDRFALACERLQTGGASCG", "output": "Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase."}]}
+{"id": "function_test_2272", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAASARGLRTLQSAHSSTTVPRLQLAVSRCYATTTSPDPPITNSSNSSNSTPTPKQRITAFKDKLNAGPSFSDFVSGGGGGASNDRVPLDPAEAYALKTALVGPPGRKKQIIRLPSWLKTPIPDTPNYRRIKSDLRGLNLHTVCEEARCPNISDCWGGSSKSAATATIMLMGDTCTRGCRFCSVKTSRTPPPLDPHEPENTAEALSRWGLGYVVMTSVDRDDLADGGARHVAETVRKVKQKAPGILLECLTGDYAGDLEMVALVATSGLDVFAHNVETVEALTPFVRDRRATFQQSLRVLKAAKEARPELITKTSIMLGLGETETQLWETLRALRTVDVDVVTFGQYMRPTKRHMAVHEYVRPGVFDLWKERALEMGFLYCASGPLVRSSYKAGEAFIENVLKKRRGEGADGGDGGNSTRREDVERLVAGGVVR", "output": "Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives."}]}
+{"id": "function_test_2273", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTAKFRILVLNGPNLNLLGKREPGIYGAATLDDIVGRLQQLAAELDVELTHKQSNAEYELVDTIHQAMGTVDFILINPAAFTHTSVAIRDALLGVAIPFIEIHLSNVHAREPFRHHSFLSDVAKGVICGLGADGYEFALTAAVRHLERSSNN", "output": "Catalyzes a trans-dehydration via an enolate intermediate."}]}
+{"id": "function_test_2274", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRVLAALSGGVDSAVAAARAVDAGHDVVGVHMALSRTRAQHRTGSRGCCSIEDASDARRAADVLGIPFYVWDLSEEFTDTVVADFLSEYAAGRTPNPCVRCNEHIKFSALLDRGLALGFDAVATGHYARIERGAAGVPELHRAADAAKDQSYVLAVMGPERLARSLFPLGEVPTKDAVRAEAAARGLSVSAKPDSYDICFVADGDTQGFLRSHLGSQPGPVLDTDGREVGAHDGAYAFTVGQRKGLRLPRPAADGRPRYVVDVRTASNTVVVGPAELLSVRDVLGERPVWLAEEPHEWTDATVQVRAHGAALPARIRTVTDDDGASHLAARLAEPLRGLAAGQSVVAYDGTRVLGQATVAATGRDAVAAAPALAGVGSTA", "output": "Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34."}]}
+{"id": "function_test_2275", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLMSLAQWLQTLSPEFGFLRVFQYLTFRALMAALTALVVGLVAGPYVIRRLAALKIGQPVRGYGMETHLTKSGTPTMGGVLVLFAIAFATLMWFDPSNRFVWIVLWVTLGFGAIGWVDDWRKVVRKDPEGMRSREKYFWQSVVGLIAGFYLLFSISESSNWRVLQLFFAWVQSGFDLDFPPKINLLVPFFKEVSYPLGGIGFVILTYLVIVGASNAVNLTDGLDGLAIMPVVMVGSALGVFAYVTGSAVYSKYLLFPNIPGSGELLVFCSAMAGAGLAFLWFNTHPAQVFMGDVGALALGGALGTIAVIVRQEIVFFIMGGIFVVEAISVMAQVMYFKYTKKRYGEGRRVLKMAPLHHHFEKSGWRETQVVVRFWIITMLLCLIGLSTLKLR", "output": "Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I."}]}
+{"id": "function_test_2276", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEQFHATTIFAIHHNGKAAMAGDGQVTFGNAVVMKHTAKKVRRLFQGKVLAGFAGSVADAFTLFEMFEGKLEEFNGNLPRAAVELAKEWRSDKVLRRLEAMLIVMDERHLLLVSGTGEVIEPDDGILAIGSGGNYALAAGRALKQYAGDQLSAKEIAKAALEIAANICVYTNDHIIVEEL", "output": "Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery."}]}
+{"id": "function_test_2277", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIRHRLRLALSAAPVTATGRRTRSKTAPRRSLSTQQTQSSASSSSNNLDGDGRAFVPLRKQLKDESKAKRLTGRGKRSKSASSQVEGWELTVGIEVHAQLDTDSKLFSRASAAHDDAPNANVALFDLAFPGSQPWFQPATLIPALRAAIAFGCEIQSVSHFDRKHYFYQDQPAGYQITQYYEPYARSGALWLYPHDGIAPEDGDAVRVGIKQIQMEQDTAKSQELPSHTVLLDFNRVSRPLIEIITLPEIHSPATAAACVRKIQALLQSCGAVNTGMEMGGLRADVNVSVRRTGQVEQHGYEGVSGLGQRTEIKNLSSFKAVEDAIIAERDRQIAVLEGGGKVEGETRGWTIGSTETKRLREKEGSVDYRYMPDPDIGPVVVGAELVERLRTSMPPSPDELLRMLTQDPMYMLTVEDAKPLIELDDCARLEYYLDAVDSLVVLQRDAAAAAAASAASTVSATGKTVGNWVLHELGGLFSRADAAWDGERVPASSLAAIVHLVGTKQITGSTAKSLLSTVFAGEHGGRTVQEMVEQDGLLLRPLAQEEYVSMARTVMAQHPQLVEQIRQGQQGKIGFFVGQIKRMGERGRVEAQRAEEAVRSLL", "output": "Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)."}]}
+{"id": "function_test_2278", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPSLTQTRSTVSELNTSAIETSTMSDSGHQNKPKGPKGITFSGETFIVPETHDMVKTLFDPTIKKSNFELIILGLLFSNLLVFLIPNNNLRISIFIGFYIFWRLSYNFGIGWLLQHQSNDHLLVQWAIKYKLFDKNNKNFLAKLVQSEIKSQRGDAYDINSYPIEFNTWLIFRKFVDLILMSDFTTFICVVYACSINNDYQFIKNQPSWLTMSRIVGGSILILFNYWVKVNAHNTIKDYAWYWGDFFFRQINNEELIFDGVFEMFPHPMYSVGYVGYYGFALISKSYIVLLTAIFGHFLQMIFLHYIENPHIDKIYGPSKNEINLIKILKLKDLKNFDNLKPLVGLYNFNWMRASDVINLVLSLTYGLIIPVFAKSLKSLFVLTVATKLFESLSINILLILQSQFKFFTKWSLSNDIPIEKSLNNWAVLYNSLINLTYSSLFGLNLGYFLQGTGSSLVTDYFYLRLFLGLCLIYTQSWINLSIIDSIGYFGWFYGDFFIPKSQSSIKNLTQAGVYRYLNNPEQIFGVCGVMGVFLIHPTVENLTCCILWMVNNFVRINFIEKIHMIRIYGEKEVNRDSGVTKTVKKHLIPDVIQRKMSNDDPKRRGGVANGTSLGDSLDNFIKELRNSTTKLSQQKLIELSQNLSFANSNYKLSIDGLKESNELKYTTIGTPITVSWQSPSNTHSIRDWVGLYKIVQTSYSRNKTILSSAGRWTYCTDSKGVFTFEKEKLFWEEGVYEFRYHLDGKHDVAYISEPFEIKSVDIDVPGDISEAGEFSKQLKTEIFDKIIDIKSINESIAPIANQADNVIEVYKLFSSLISKSTQINVNYRIFLNNDNLSISDVAHKLIDIKQVLQELSFNSSEKKNL", "output": "Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME)."}]}
+{"id": "function_test_2279", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGVEKRINDEEMQPLAERDDKSRDSIDSTSTASISLALLGGANGSAHGSRAARTRKSENQEKYHDDEEEGDLEEGFVPPAGGWSAPRKVSVIFTLIVTLCIAGWLVAFFVLLGRHKDSSKDAAVSQGESNIIPGIYSGGRGGKKLDLDGVLFGNWSPKSHDISWFPGPNGADGLLLEQGGDRNKAYLRVEDIRSRNPGNKADDTIVLMRESSFMVGKRLVRPSKVWPSPDLKTVLVMSDQRKNWRHSYTGNYWIFDVETQTGEPLDPESLDGGIQLASWSPNSDAIVFTRKNNMFIRRLPSKNVKQITTDGGTNLFYGIPDWVYEEEVFSDSSATWWDGDGKFVAFLRTNESRVPEYPVQYFIPNTNKPSRPSEENYPDIRKIKYPKAGAPNPVVNIQFFDVEKEEVFSVDVKDDLPDDDRLVIGVTWASNGNVLVRETNRESDRLSVVLIDAAKRAGKVVRSRNFSSLDGGWVEPSQTTHFVPADPKNGRPHDGYIETIPHDGFEHLAYFTPMDNSEPTVLTSGDWEVVDAPSAVDLKRGLVYFVAAKENPTERHIYTVKLDGSDLQPIVDTKSAGYYSISLSAGAGYALLKYEGPDIPWQKVISTPANEEKYEESIEKNPGLADMARKYALPSLHYQTITISGYELQVVERRPANFNPDKKYPVLFHLYGGPGSQTVTKKFKVDFQSYVASNLGYIVVTVDGRGTGFIGRKARCAVRGNLGHYEAIDQIETAKAWGKRSYVDAGRMAIWGWSYGGFMTLKTLEQDAGQTFQYGMAVAPVTDWRFYDSIYTERYMHTPQNNPEGYDRSAISNVTALDQAVRFMIVHGSGDDNVHIQNTLTLLDKLDLGSVKNFDVHVYPDSDHSIYFHNANKMVYQRLSDWLVNAFNGEWVKTRDPIPHKSLARRALGLINILRNG", "output": "Type IV dipeptidyl-peptidase which removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline."}]}
+{"id": "function_test_2280", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSVLETFDPAVAEVIRHETERQEYNLELIASENFVSPAVLEAQGSVLTNKYAEGYPGKRYYGGCHCVDVVENLAIDRAKELFGADHVNVQPHSGSQANMAVYFSVLKPGDTVLGMNLAHGGHLTHGSPVNFSGKLFNIVPYGVSKETQTIDYEETERLALEHKPKMIVVGASAYPRIIDFEAFRRIADKVGAVVMVDMAHIAGLVAAGLHPSPVPYAEFVTTTTHKTLRGPRGGMIMCREEWAKTLNSNIFPGIQGGPLMHVIAAKAVAFKEALTPEFKKYQEQIVKNAKALAEGLTKRGFKLTSGGTDNHLMLVDLSQTELTGKVAEEALDRAGITVNKNGIPFDTRSPFITSGIRIGTPAATSHGLKEAEMEQVAGFIADVLGNVTDEAKLAAVKTQVNALMKRFPMYADRLA", "output": "Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism."}]}
+{"id": "function_test_2281", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRISASTVLLGAASAASAASFQNQAQQVLADNFHKAHDAIKPVADSFAHTTLESFEEAFNGMNSQAKALWDEIKLLVPESAFDKPTWFSKPKAAKRRKDWDHVVKGADVQKLWVKGADGEKHREVGGQLDNFNLRVKSVDPSKLGVDKVKQYSGYLDDEANDKHLFYWFFESRNDPKNDPVVLWLNGGPGCSSLTGLFLELGPSSIDKKLKVINNEYAWNNNASVIFLDQPVNVGYSYSGNAVSNTVAAGKDVYALLTLFFHQFPEYAKQDFHIAGESYAGHYIPVFASEILSHKDRNINLKSVLIGNGLTDPLTQYEHYRPMACGEGGYPAVLSESECRSMDNALPRCQSLIRNCYESGSVWSCVPAAIYCNNQFIGPYQRTGQNVYDIRGKCEDDNNLCYSALGWISDYLNQKDVMDALGVEVESYDSCNFDINRNFLFQGDWMQPFHRLVPGILKEIPVLIYAGDADFICNWLGNKAWSEALEWPGKKGFNKAELEDLSLPEADKEYGKVKSSGNFTFMQIYQAGHMVPMDQPENSLDFLNRWLGGEWFEQ", "output": "Vacuolar carboxypeptidase involved in degradation of small peptides. Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (By similarity)."}]}
+{"id": "function_test_2282", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSFDGMFTYGMTHELNEKIMGGRITKVHQPYKHDVIFHIRAKGKNQKLLLSAHPSYSRVHITAQAYENPSEPPMFCMLLRKHIEGGFIEKIEQAGLDRIMIFHIKSRNEIGDETVRKLYVEIMGRHSNIILTDAAENVIIDGLKHLSPSMNSYRTVLPGQDYKLPPAQDKISPLEASEDDILRHLSFQEGKLDKQIVDHFSGVSPLFAKEAVHRAGLANKVTLPKALLALFAEVKEHRFIPNITTVNGKEYFYLLELTHLKGEARSFESLSELLDRFYFGKAERDRVKQQAQDLERFVVNERKKNANKIKKLEKTLEYSENAKEFQLYGELLTANLYMLKKGDKQAEVINYYDEESPTITIPLNPNKTPSENAQAYFTKYQKAKNSVAVVEEQIRLAQEEIEYFDQLIQQLSSASPRDISEIREELVEGKYLRPKQQKGQKKQKPHNPVLETYESTSGLTILVGKNNRQNEYLTTRVAARDDIWLHTKDIPGSHVVIRSSEPDEQTIMEAATIAAYFSKAKDSSSVPVDYTKIRHVKKPNGAKPGFVTYDSQHTVFVTPDADTVIKLKKS", "output": "Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits.; "}]}
+{"id": "function_test_2283", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGMRMMFTVFLLVVLATTVVSFTLDRASDGANAAADLVARGIRGNCCMFHTCPIDYSRFYCP", "output": "Probable neurotoxin with unknown target. Possibly targets ion channels."}]}
+{"id": "function_test_2284", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MASGTTTTAVKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLARHGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTLKENANKAKSLLLTTIPQIGSTEWSETLHNLKNMAQFSVLLPRH", "output": "Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates."}]}
+{"id": "function_test_2285", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGGIIKLSFLFCSLISLVNSENTGKLPTAISDHSVPKATATTDPSVFVLSNDFEITDVPTTREYTFNLTEALASPDGYERLVYAVNNMLPGPVIEANTGDTVIVHVNNYLHEGQGIHWHGLRQNGTALMDGVPGITQCSIPPGGSFTYQFTVSHQSGTFWWHSHYSNSMADGIWGPLIVHSPNEPLQRGRDYDEDRIVAVTDWMHDESETIVEALISSEGYRGRPFPPQGDAILINGRGQTNCTATGSPSCTYPPPPEIHVPVNCRVRLRFISAASHPMYRISIDNHSMEIVETDGTAVYGPTIHEISISSGERYSVIINTTEGKEGDAFWLRTSVALDCMAQGVTQVGLAVVRYTGNGSITTAEPRTEAWTDLARPDTPCVGLDEMYHLSPRELVNASQTALESRVLDSKLGKFVDVYGNSFEGYGFNNVTYQNQINDPLLYVVQRGGTCNSSLIANATFADIGPVNIIINNLDSHIGHPYHMHGTEFQLMGRGTGALTLDDLPNTNLTLDNPTRKDTIWMQGGSWALLRIISDNPGVWALHCHIGWHLAKGKMAVVVVQPEAIKKIQWPESWMDLCANTDPNAFGPARRSVS", "output": "Laccase that catalyzes the oxidation of certain aromatic compounds, including L-dopa, to quinones, which then polymerize to melanin (By similarity). Able to oxidize a wide variety of aromatic diphenol and diamino groups in the ortho, meta, and para positions but not monophenolic groups such as in phenol, tyramine, or tyrosine (By similarity). Plays an important role in virulence (By similarity). Plays a role in dissemination to extrapulmonary sites but is not involved in pulmonary growth or in elicitation of cellular immune responses in the lung (By similarity)."}]}
+{"id": "function_test_2286", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEFNLVTIGFTIVNFIILMLILKHFFFDKVNKVIDDRNNEVALTIKKADAQNEEARLLKVESEKNLEDSKLQGKTIVENYKVKAEKVSEEITAEAKTEAQNILERAKRETQREKEKAEDEIKNQVVELAVLISSKALENSINEAEHRKLIEDFVSKVGI", "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "}]}
+{"id": "function_test_2287", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLHAFERKMAGHGILMIFCTLLFGVGLWMHLVGGFEIIPGYILEFHVPGSPEGWARAHSGPALNGMMVIAVAFVLPSLGFADKKPHLLGNIIILDGWANVGFYFFSNFSPNRGLTFGPNHFGPGDIFSFLALAPAYLFGVLAMGALAVIGYQALKSVGSRKAVPHATAE", "output": "Epoxystyrene isomerase that catalyzes the second step in the aerobic styrene degradation pathway by converting epoxystyrene to phenylacetaldehyde."}]}
+{"id": "function_test_2288", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSNSGKKLTQKLKKNLPVTGPQAPTLYELMQWYCLNTNTHGCRRIVVSKGRLRRWIWIVLTLIAVALIFWQCALLLMTYYSVSASITVTFQKLVYPAVTICNLNPYSYSKIKDRLATLEKTTNQTLKKIYGFTEPLIRSKRDLDVNDENSTEDIFLKQIPLFRLESIKGNQLVVSDLKTKKRTQISGKVIQRDAGSVQDSDNMVGFKLCDANNSSDCTIFTFGSGVNAIQEWYRLHYNNILAKISMEDKIAMGYKADELIVTCLFDGLSCDARNFTLFHHPLYGNCYTFNSAERGNLLVSSMGGAEYGLKVVLYIDEDEYNPYLSTAAGAKILVHDQDEYPFIEDLGTELETGTETSIGMQLTESTKLSDPYSDCTIDGSDISVENLYNKKYTLQICLNSCFQREMVRSCGCAHYDQPLPNGAKYCNYEEYPNWIYCYVKLYKQFVQEELGCQSTCRESCSFKEWTLTRSLAKWPSLNSEEWMLRVLSWELGEKLNKNLTKNDLGNLNIFYQDLNSRSISESPTYNIVTLLSNFGGQLGLWMSCSMVCGLEIVEVFFIDSFWVILRQKWHKLCNWWKNRKENEIEEIPDITVPAMAGHNNPLCVDHPICLGEDDPPTFHSALQLPQAQDCRVPRTPPPKYNTLRIQSAFHLETIDSDEDVERF", "output": "Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus."}]}
+{"id": "function_test_2289", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLSLKAQSSVVGKSSSLRLVRNFSKNVRALSQVADETKPGDDDLVQIDLPETSFEGYLLDVPELSYQTTKSNLLQMYKDMIIVRRMEMACDALYKAKKIRGFCHSSVGQEAIAVGIENAITKRDTVITSYRCHGFTYMRGAAVQAVLAELMGRRTGVSFGKGGSMHLYAPGFYGGNGIVGAQVPLGAGLAFAHQYKHEDACSFALYGDGASNQGQVFESFNMAKLWNLPAVFCCENNKYGMGTAAARSSAMTEYFKRGQYIPGLKVNGMDILAVYQASKFAKDWTVSGNGPIVLEYETYRYGGHSMSDPGTTYRTRDEIQHMRSKNDPIAGLKMHLLELGIATEDEIKAYDKAARKYVDEQVELADAAPAPEAKMSILFEDVYVPGSETPTLRGRLQEDTWDFAKKSFAFRD", "output": "The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3)."}]}
+{"id": "function_test_2290", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTHNKTIKKVYIVGAGPGDPELLTLKAQRVLREADVVIYDALVNPEILQHCKPNAEIIKVGKRRNNHSFSQLQIASLLIDRAKKGERVIRLKGGDPLIFGRLGEEILELFSKNIEIEIIPGITSAFAVAADMKFPLTHRQLGSSITFLTGEEFYEKTTNKLKWERIIWGADTIIVYMILYNLPKIIKKFLSVGYSAEKPIVLVQWASLKKKNFLIGTIGTIIHQVIESKFGPPSLAIIGEVIEISSIIQKL", "output": "Catalyzes the two successive C-2 and C-7 methylation reactions involved in the conversion of uroporphyrinogen III to precorrin-2 via the intermediate formation of precorrin-1. It is a step in the biosynthesis of both cobalamin (vitamin B12) and siroheme."}]}
+{"id": "function_test_2291", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSWTEKYRPGSFDEVVGNQKVIAEIKEWIKAWKAGKPQKPLLLVGPPGTGKTTLAHIIGKEFSDTLELNASDRRSQDALMRSAGEASATRSLFNHDLKLIILDEVDGIHGNEDRGGVQAINRIIKESRHPMVLTANDPYSKRLQSIKPRCRVLNLRKVHTSSIAAALRRICRAEGIECPDDVLRELAKRSRGDLRSAINDLEAMAEGEERIGEELLKMGEKDATSNLFDAVRAVLKSRDVSKVREAMRVDDDPTLVLEFIAENVPREYEKPNEISRAYDMLSRADIFFGRAVRTRNYTYWRYASELMGPGVALAKDKTYRKFVRYTGSSSFRILGKTRKQRSLRDSVAAKMAGKMHISPKVAISMFPYMEILFENDEMAYDISEFLELRDEEIKLFRKRKIKAPKRKKTPRKAEIKVGPLYSQKKDKGADKSINDKATDKSAKTPIKSSKKDDRPRDESSSSSDDKKPKEKQTSLFQFS", "output": "Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA. The complex possesses DNA-dependent ATPase activity which is further stimulated by PCNA. In conjunction with PCNA stimulates DNA synthesis by PolB, relieving inhibition by replication protein A (RPA)."}]}
+{"id": "function_test_2292", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRNSVEFSQLGLKTAFNLSQNKTYTSAVKKQFFSTGAFLSNGGNIDLNKHTQKNIDSKYVACNSRSVTPPNDVASSVSKNTLRHKQRLMMAQWLMSPEVQKAKSSSSGNVGLGPNTNQPFPLNPFFKPPRPISHSLRMKITDEYLQGASIEVLARKFNTSPQRIEALIKLRRINDEFEEKKKPILHSYNEVMEKMLNACTKPEMMQFNDGNDIPLRSNPVSLWKSLPEGETFTPQEAAKILKWPSIEELNMRQNATHFHKTSDEHKDLNEDEELISSSPSEVGKRVFRLIDLSTGNVYRRDTGGDIYVKRKKSTT", "output": "Required for mitochondrial protein synthesis. Has a role in mitochondrial integrity and cell respiration."}]}
+{"id": "function_test_2293", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MMMSLFNTFESPYFLGFPLMIFIAILISLTMFIPDNNLLIKNQSSMLASTFLKTMTKEIFSPIKKSGHSWALLLMTTLMFIFLNNITGLLPYTFTVTSQLSLNMAMAIPLWLGTIIMGATSQPSHSLAHLLPEGTPMTLAPFLIVIESISIIIRPLALGVRLTANITAGHLLIHLVSLALINLTKSLPLLFLTFSVFILLLILELAVSFIQAYVFVMLVSLYLEENLI", "output": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane (By similarity)."}]}
+{"id": "function_test_2294", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVQLFGGALCADFPPKFLDASVLRQIPDNQEVFLQDSKENLTVIIELLEKIEKPFDGSVAAYHFNSIAFDNDASQRVIWRDKSLGEDDFEGMRSEKASGSSVQGCQRVLEKGKRNPESATNVAIFVNVITLIDFQTDIVISVNAPLPNTSSVPSSVENIPPSDQSIVRAALETIQRVTRSLVLVDKTVFA", "output": "Involved in the Ran-GTPase system for nuclear protein import and poly(A)+ mRNA export. Required for mitosis-to-interphase transition."}]}
+{"id": "function_test_2295", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTNKCLLQIALLLCFSTTALSMSYNLLGFLQRSSSFQCQKLLWQLNGRLEYCLKDRMNFDIPEEIKQPQQFQKEDAALTIYEMLQNIYAIFRQDLSSTGWNETIVENLLANVYHQIDHLKTILEEKLEKEDFTRGKFVSSLHLKRYYGRILHYLKAKEYSHCAWTIVRVEILRNFFFINKLTGYLRN", "output": "Type I interferon cytokine that plays a key role in the innate immune response to infection, developing tumors and other inflammatory stimuli. Signals via binding to high-affinity (IFNAR2) and low-affinity (IFNAR1) heterodimeric receptor, activating the canonical Jak-STAT signaling pathway resulting in transcriptional activation or repression of interferon-regulated genes that encode the effectors of the interferon response, such as antiviral proteins, regulators of cell proliferation and differentiation, and immunoregulatory proteins (By similarity). Signals mostly via binding to a IFNAR1-IFNAR2 heterodimeric receptor, but can also function with IFNAR1 alone and independently of Jak-STAT pathways. Elicits a wide variety of responses, including antiviral and antibacterial activities, and can regulate the development of B-cells, myelopoiesis and lipopolysaccharide (LPS)-inducible production of tumor necrosis factor. Plays a role in neuronal homeostasis by regulating dopamine turnover and protecting dopaminergic neurons: acts by promoting neuronal autophagy and alpha-synuclein clearance, thereby preventing dopaminergic neuron loss. IFNB1 is more potent than interferon-alpha (IFN-alpha) in inducing the apoptotic and antiproliferative pathways required for control of tumor cell growth (By similarity)."}]}
+{"id": "function_test_2296", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKTLLLTLVVVTIVCLDLGYTLKCNKLVPLFYKTCPAGKNLCYKIFMVATPKVPVKRGCIDVCPKSSLLVKYVCCNTDRCN", "output": "Shows cytolytic activity on many different cells by forming pore in lipid membranes. In vivo, increases heart rate or kills the animal by cardiac arrest. In addition, it binds to heparin with high affinity, interacts with Kv channel-interacting protein 1 (KCNIP1) in a calcium-independent manner, and binds to integrin alpha-V/beta-3 (ITGAV/ITGB3) with moderate affinity."}]}
+{"id": "function_test_2297", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLISTFIISSLLSIALANPIPSRGGTQFYKRGDYWDYQNDKIRGVNLGGWFVLEPFITPSLFEAFENQGQDVPVDEYHYTKALGKDLAKERLDQHWSSWIVEADFQSIAGAGLNFVRIPIGYWAFQLLDNDPYVQGQESYLDQALEWAKKYDIKVWIDLHGAPGSQNGFDNSGLRDSYEFQNGDNTQVALDVLQYISNKYGGSDYGDVVIGIELLNEPLGSVLDMGKLNDFWQQGYHNLRNTGSSQNVIIHDAFQTWDSFNDKFHTPDYWNVVIDHHHYQVFSPGELSRSVDEHVKVACEWGANSTKENHWNLCGEWSAAMTDCTKWLNGVGRGSRYDQTFDYDPSQNQNYIGSCQGSQDISTWDDDKKSNYRRYIEAQLDAFEKRSGWIFWTWKTETTLEWDFQKLSYYGIFPSPLTSRQYPGQCD", "output": "Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. It could also function biosynthetically as a transglycosylase (By similarity)."}]}
+{"id": "function_test_2298", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKFFIFTCLLAVVLAKHEMDQGSSSEESINVSQQKFKQVKKVAIHPSKEDICSTFCEEAVRNIKEVESAEVPTENKISQFYQKWKFLQYLQALHQGQIVMNPWDQGKTRAYPFIPTVNTEQLSISEESTEVPTEESTEVFTKKTELTEEEKDHQKFLNKIYQYYQTFLWPEYLKTVYQYQKTMTPWNHIKRYF", "output": "Important role in the capacity of milk to transport calcium phosphate."}]}
+{"id": "function_test_2299", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSGTDKVRVNVSQTAQTPLHTSAKLPKVGVLLVNLGTPDGTSYGPMRRYLAEFLSDRRVIEWSRLIWYPILYGIVLNTRPRRSGRLYDRIWNHENNESPLRTYTRAQGEKLAKALSDQPNVVVDWAMRYGQPSIESITDRLLQQGCERIVIFPLYPQYSATTTATVNDKFFEALMKKRFMPAIRTVPSYEAEPVYIDALARSVEKHLATLSFKPEVILTSYHGIPKSYSDKGDPYRQQCLETTRLLRERLGLGEDEMRATFQSRFGPEEWLQPYTDETVKELAKNGVKLVAVLNPGFVADCLETVDEIGNEAAEEFLENGGENFSHIPCLNDSEEGMKVIETLVRRELLGWV", "output": "Catalyzes the ferrous insertion into protoporphyrin IX."}]}
+{"id": "function_test_2300", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLSVPHLDRDFDYLVPAEHSDDAQPGVRVRVRFHGRLVDGFVLERRSDSDHHGKLGWLDRVVSPEPVLTTEIRRLVDAVAARYAGTRQDVLRLAVPARHARVEREITTAPGRPVVAPVDPSGWAAYGRGRQFLAALADSRAARAVWQALPGELWADRFAEAAAQTVRAGRTVLAIVPDQRDLDTLWQAATALVDEHSVVALSAGLGPEARYRRWLAALRGSARLVIGTRSAVFAPLSELGLVMVWADADDSLAEPRAPYPHAREVAMLRAHQARCAALIGGYARTAEAHALVRSGWAHDVVAPRPEVRARSPRVVALDDSGYDDARDPAARTARLPSIALRAARSALQSGAPVLVQVPRRGYIPSLACGRCRAIARCRSCTGPLSLQGAGSPGAVCRWCGRVDPTLRCVRCGSDVVRAVVVGARRTAEELGRAFPGTAVITSAGDTLVPQLDAGPALVVATPGAEPRAPGGYGAALLLDSWALLGRQDLRAAEDALWRWMTAAALVRPRGAGGVVTVVAESSIPTVQSLIRWDPVGHAEAELAARTEVGLPPSVHIAALDGPAGTVTALLEAARLPDPDRLQADLLGPVDLPPGVRRPAGIPADAPVIRMLLRVCREQGLELAASLRRGIGVLSARQTRQTRSLVRVQIDPLHIG", "output": "Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA."}]}
+{"id": "function_test_2301", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIINFASENGLQSWQQCDVTMVRNFAVRSRRKGLGAASLALRLSALRSFFDWLVSQNELKANPAKGVSAPKAPRHLPKNIDVDDMNRLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHLDLESGEVWVMGKGSKERRLPIGRNAVAWIEHWLDLRDLFGSEDDALFLSKLGKRISARNVQKRFAEWGIKQGLNNHVHPHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK", "output": "Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerD binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerC specifically exchanges the top DNA strands (By similarity)."}]}
+{"id": "function_test_2302", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MERRLVVTLQCLVLLYLAPECGGTDQCDNFPQMLRDLRDAFSRVKTFFQTKDEVDNLLLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPEAKDHVNSLGENLKTLRLRLRRCHRFLPCENKSKAVEQIKNAFNKLQEKGIYKAMSEFDIFINYIEAYMTIKAR", "output": "Inhibits IFN-gamma synthesis. Down-regulates the expression of the host TAP1 gene (transporter associated with antigen processing), thereby affecting the transport of peptides into the endoplasmic reticulum and subsequent peptide loading by MHC class I molecules. In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes (By similarity)."}]}
+{"id": "function_test_2303", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSCTASYAGMTTPVKDKEGHGIPCLQPIDVVECTYQYFTKSRNKLSLRVGDLIYVLTKGSNGWWDGVLIRHSANNNNNNSLILDRGWFPPSFTRSILNELHGVPDIGNELEIFQAGLNLKLELSSNPVILSLEDFLDCCRDIEFKEQLAWSPTPVHERKGCCELLYYNQDLDVYCRTLPYLPQNQVETVNDYSSFPAISKIAGKKMPITSSPDLFYLNDCDVVYWYDLTRLVCHYVNLTERDLLANEREKFLTSLDLLTAQITYVYMLFRNLRLVEDSFKKTLKKLIYTLSRFSINANIWFHSTSFEEREAIASQKDPERRSPLLQSILGTFQKFHFLLRLLHFLSNPNELTILPQLTPRFFKDSFNTISWNNPFLRTVFNQHMSMTLPRQMIKAVAGASGIVAENIDEIPASKQGTFISSETSHHSPSAPFQRRRRGTIFSNVSGSSDESDTIWSKRKKPYPLNEETLSLVRARKKQLDGKLKQMIKSANEYLSNTANFSKMLNFEMNFKTYEEVSGTIPIIDILENLDLTIFLNLRELGDENRVFDEDVAIGDEDKEFLKHSLSSLSYILSDYFNMKQYFHDVVVKFIIVAQHLTLEDPFVFSPMQNDLPTGYYEPMKPSSLNLDNAKDKKNGSQNTDIQEEEDEYEPDPDSLILFHNLINQDSDFNDLKFFNLAHVFKKSCDDYFDVLKLAIEFVNQLILERENLLNYAARMMKNNITELLLRGEEGYGSYDGGETAEKSDTNAVYADSDTKDNDEWRDSQVKLPRYLQREYDSELIWGPIVRIKGGSKHALISYLTDNEKKDLFFNITFLITFRSIFTTTEFLSYLISQYNLDPPEDLCFEEYNEWVTKKLIPVKCRVVEIMTTFFKQYWFPGYDEPDLATLNLDYFAQVAIKENITGSVELLKEVNQKFKLGNIQEATAPMKTLDQQICQDHYSGTLYSTTESILAVDPVLFATQLTILEHEIYCEITIFDCLQKIWKNKYTKSYGASPGLNEFISFANKLTNFISYSVVKEADKSKRAKLLSHFIFIAEYCRKFNNFSSMTAIISALYSSPIYRLEKTWQAVIPQTRDLLQSLNKLMDPKKNFINYRNELKSLHSAPCVPFFGVYLSDLTFTDSGNPDYLVLEHGLKGVHDEKKYINFNKRSRLVDILQEIIYFKKTHYDFTKDRTVIECISNSLENIPHIEKQYQLSLIIEPKPRKKVVPNSNSNNKSQEKSRDDQTDEGKTSTKKDRFPKFQLHKTKKKAPKVSK", "output": "Promotes the exchange of Ras-bound GDP by GTP."}]}
+{"id": "function_test_2304", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSWQAYVDDHLMCDIEGHEGHRLTAAAIVGHDGSVWAQSATFPQFKPEEMNGIMTDFNEPGHLAPTGLHLGGTKYMVIQGEAGAVIRGKKGSGGITIKKTGQALVFGIYEEPVTPGQCNMVVERLGDYLLEQGL", "output": "Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations (By similarity)."}]}
+{"id": "function_test_2305", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "LICVKEKFLFSETTETCPDGQNVCFNQAHLIYPGKYKRTRGCAATCPKLQNRDVIFCCSTDKCNL", "output": "Binds weakly to the muscarinic acetylcholine receptor (CHRM) (By similarity). Does not show inhibition on GABA(A) receptors ."}]}
+{"id": "function_test_2306", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MADWDKVNSVWSAMEANITAVGQNILLRLFEQYPESQSYFPKLKNKSLGELKDTADIKAQADTVLKALGNIVKKKGNHSQPVKALAATHITTHKIPPHYFTKITTIAVGVLSEMYPSEMNAQAQEAFSGAFKSICSDIEKEYKAANFQG", "output": "Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles."}]}
+{"id": "function_test_2307", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGVQGLWKLLECSGRPINPGTLEGKILAVDISIWLNQAVKGARDRQGNAIQNAHLLTLFHRLCKLLFFRIRPIFVFDGEAPLLKRQTLAKRRQRTDKASNDARKTNEKLLRTFLKRQAIKAALSGNKQSNEELPSFSQVPRKETEDLYILPPLEDNENNSSEEEEEREWEERMNQKQRLQEDFFANPSSVDIESEEFKSLPPEVKHEILTDMKDFTKRRRTLFEAMPEDSSDFSQYQLKGLLKKNDLNKCIDNVRKELNQQYSGEVQAQFESEGGFLKEVETRRLVSEDDSHYILIKGIQSKQEEKKVDSPPQSITFNSSQTPKTYLDLKLASAHKTKPLQTSSAEAAPPSPRTLFAIQEAMAESWDHEKHEKPSVSGCEAEGNVSPRTLQAIYQVLAEDEAGESNKIKVVLQSDEERKPKTKVLVISSSDEEDDCLNYQDGTKTTLGASLIKSISPSSMQCQESTADSLPNYTRSKPVSQIEEPMADHNLQGDNCNVPNAKDKLIVPPSLGNVDKPIILSNTIPVNSEFRIPLLPVNMSMRETVIIPNNTGSLGSSRYISLERDATKQGFSDNPVGDLVRSPDEPALNASSALSDRKTSATQSLLCNNIECTEQSMVQGCSNTLDVTQTTQPSGGSEVNKPAEYNPQDKKVFGSNDSSAMYVPMTPESIIVSDEEFVNEKEDSDSDDSFIEVDSEFSTSNSQHVVFKEPGDTRETATNFQAVEEGNSGSQDIPLEHDSGEPHEQSNSEESKDLDDVSNEWQDISVEELESLENNLYVQQTSLQAQQQQQERIAATVTGQMCLESQELLQLFGIPYIVAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYKNFFSQNKHVEYYQYADIHNQLGLDRSKLINLAYLLGSDYTEGIPTVGYVSAMEILNEFPGQGLEPLVKFKEWWSEAQKDKKMRPNPNDTKVKKKLRLLDLQQSFPNPAVASAYLKPVVDESKSAFSWGRPDLEQIREFCESRFGWYRLKTDEVLLPVLKQLNAQQTQLRIDSFFRLEQHEAAGLKSQRLRRAVTCMKRKERDVEAEEVEAAVAVMERECTNQRKGQKTNTKSQGTKRRKPTECSQEDQDPGGGFIGIELKTLSSKAYSSDGSSSDAEDLPSGLIDKQSQSGIVGRQKASNKVESSSSSDDEDRTVMVTAKPVFQGKKTKSKTMKETVKRK", "output": "Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Binds and bends DNA repair bubble substrate and breaks base stacking at the single-strand/double-strand DNA junction of the DNA bubble. Plays a role in base excision repair (BER) by promoting the binding of DNA glycosylase to its substrate and increasing DNA glycosylase catalytic activity that removes oxidized pyrimidines from DNA. Involved in transcription-coupled nucleotide excision repair (TCR) which allows RNA polymerase II-blocking lesions to be rapidly removed from the transcribed strand of active genes. Required for DNA replication fork maintenance and preservation of genomic stability. Involved in homologous recombination repair (HRR) induced by DNA replication stress. During HRR, binds to the replication fork with high specificity and stabilizes it."}]}
+{"id": "function_test_2308", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDPVVVLVLCLSCLLLLSLWKQSHGGGKLPPGPTPLPILGNILQIDFKDISKSLQNLSKVYGNVFTVYMGMKPTVVMYGYEAVKEALVDLGEEFSGRNLSPINKKVNKGLGVIFSNGKRWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTNGSPCDPTFILGAAPCNVICSVIFQNRFDYKDETFLNLMGKFNENFRILNSPWLQVCNIFPILMDYLPGTHKTVFENFDYVRNFVLEKTKEHQESLDINNPRDFIDCFLIKMKQEKHNQQSEFTIENLMATVTDVFAAGTETTSTTLRYGLLLLMKHPEVTAKVQEEIERVIGRHRSPCMQDRSRMPYTDATVHEIQRYINLVPNNVPHATTCNVKFRNYFIPKGTAVLTSLTSVLHDNQEFLKPDKFDPGHFLDASGNFKKSDYFMPFSTGKRVCMGEALARMELFLFLTAILQNFTLKPLVDPKDIDTTPLVSGARSCATLYQLSFIPA", "output": "Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics."}]}
+{"id": "function_test_2309", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "KYLEVLDFNHIDGCCESVSLQSGKEAVENLDTGKDSKKDTSGKGDKPQNSQTGQGSKEQTKIGTVSKDVNVGSKGKEVPRLQKITKKMNLPTVGGKIILSLDHLLEYKPNQVDLFNTRATKTEFESWYSAVKIEYDLNDEQMGVIMNGFMVWCIDNGTSPDVNGVWVMMDGEEQVEYPLKPIVENAKPTLRQIMHHFSDAAEAYIEMRNSESPYMPRYGLLRNLRDRELARYAFDFYEVTSKTPNRAREAIAQMKAAALAGINSRLFGLDGNISTNSENTERHTARDVNQNMHTLLGMGPPQ", "output": "[Nuclear inclusion protein B]: An RNA-dependent RNA polymerase that plays an essential role in the virus replication.; "}]}
+{"id": "function_test_2310", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVNGCRVRSNLLDIQRNSFRSFLKKGLVEELRKIKDIAHEGFRISFQTDNVKYKKPKISAEFALKNGETYSLSVHIPVEVTYNNMFLVRNKYILFAKIPLMTEKGTFIFNGNKRIMVNQIIRSPGVYFEKNRYNDSIFATLIPTFGSWLTFKIDQDEGIFVKVDKIKTAIPLINFLKCLGLSRKKFFLYLNDPIFIETLQESESYGIRLEFFEFYKIFFPNEVNVRFGNARKFLRSKFMDPRKYDLGEVGRFRVNTKIYRSEFFQSNRTLQPEDVLGIAHYLIELKKGMIPFDEIDDLKNKLVRSIGELLQSQFRIILNELESSLKEKLIFLYKNPSEKTFRLSRFFNSYFITNRIRKFFSVNPLSQLLDDTNSLSELTHKRKLSPFGPNGLNKERTKLDVREINTSQYGRVCPIETSEGKNAGLILSLAKDVRVDKYGFLESPFYKVLRGKIETNKGIYFISSAQEKYFTVAPFDVFRSSQSNLLDKNKLLGVKRSKIFSYSFSKNIDFISISTDQFTSLGTGLVPFLEHNDANRVLMGSNMQRQSLILLEKEVPFIKTGREALINRESDATVLAKSSGKVIYSSLKKIVIQEEEYCANIEFFNKNYSFFNLLGCLNEISQKNFKLIKKVNQKIYFLESPKKSNHGVYIQKIPIVHEGEWVRKGQIIADGMSTLRGGICLGKNVLVAYLGWEGYNFEDAVIISERLVFEDIFTSIHMKKFKTFIVNDEKKGENISMFIPNASLKTIKNLKNNGIIKIGSEIKAQDVLIGRIKVKLKNTPKNKMLIAFFGNKVRKDVSLRSPRSLVGIVTSVEILCKKSNCSVLIHVAEKRRIQIGDKIAGRHGNKGIISKIVPSIDMPFLPDGTPVDMILNPLGIPSRMNVGQVFESLLNLSSLFLKERYKIQPFDEVQTSMNSKSFVYKKLNEARKRTKKDWLFNPNYPGKAFLYDGRNCRPFDHPVAFGYAYILKLIHMVKDKIHARVTGPYSSVTQQPLRGKSKNGGQRFGEMEVWAIEGFGAAYLLQELLTIKSDDVLNRSEALFSLINGTYFSKPNIPEAFKLFILEMQSLCIDIKIFTNNYKKFD", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_2311", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSSTTLSPTTPSQLCSGKSGISCPSIALLVKPTRTQMTGRGNKGMKITCQATSIPADRVPDMSKRKTLNLLLLGALSLPTAGMLVPYGSFLVPPGSGSSTGGTVAKDAVGNDVVATEWLKTHAPGDRTLTQGLKGDPTYLVVEKDRTLATFAINAVCTHLGCVVPFNQAENKFICPCHGSQYNDQGRVVRGPAPLSLALAHCDVGVEDGKVVFVPWVETDFRTGDAPWWS", "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions."}]}
+{"id": "function_test_2312", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSSAKRSTSRVSKKKAAPAKDGAPKKREQSTRYKYVELNKASLTSAEAQHFYGVVIDATFPYKTNQERYICSLKVVDPSLYLKSQKGTGDASDYATLVLYAKRFEDLPIIHRIGDIIRVHRATLRLYNGQRQFNANVFYNSSWALFSTDKKSALQEIGGQEPASDLTPFAFSGKNYTFEKSEAALLQNIRKWAVQYFQQYNVISSDMFTPLNKAQAQKGDFDVVAKILQVFELDEYTNELKLKDQSGQVFYTLALKLKFPHLRAGEVVRIRSATYDETSTQKKVLLLSHYSNIVTFVSASKLAKEVKAKVTDDKSVEKAALKQDVSLSAVVLTEVDKKHAGLPTHSLQDLFHNADTDKEISSKDTFRTQFYITRVEPVDVKEWVKSYDRKTKKPSSHKGAGAKGGENIFQVQFLVKDASTQLNNNTYRVLLYTQDGLGANFFNVKPDNLYKNNDARKKLEEYNELLTKFNSYVDAVVERRNGFYFIKDTRIIF", "output": "May function as protective capping of the single-stranded telomeric overhang. May also participate in telomere length regulation during DNA replication."}]}
+{"id": "function_test_2313", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSFTVHIVDDEESLRDSLGFLFASRGIATRTWAAGADLLAEWPLADCGCLILDVRMEGMSGPQLLDALQARPEGLVPPVIFLTGHADVPLAVQSLKAGAFDFVEKPFNDNHIVDIALSAIAAHEGRLAEAQAREAVAARRASLSAREAEVMALMLEGLMNKQIAERLGIAMRTVEVHRSRVLAKMGARNIADLARMT", "output": "Member of the two-component regulatory system DctS/DctR involved in the transport of C4-dicarboxylates. DctR functions as a transcriptional repressor of genes for C4-dicarboxylate transport."}]}
+{"id": "function_test_2314", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MARYRHSRSRSRSRYRRRRRRRSRYRSQRRRYRRHRRSGRRRRRGRRRGYRRRYHSHRRRY", "output": "Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex."}]}
+{"id": "function_test_2315", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLDVVDLSRLQFALTALYHFIFVPLTLGLSFILVIMETIYVATGKEVYKDMTKFWGKLFGINFALGVTTGIIMEFQFGTNWSYYSHYVGDIFGAPLAIEALLAFFLESTFVGLFFFGWDRLSKGKHLLATYCVAFGSNLSAMWILVANGWMQAPTGSEFNFETVRMEMTNFLDLWLNPVAQSKFLHTLSAGYVTGAFFVLAISSYFLLKGRDFEFAKRSFSVAATFGFIASISVLILGDESGYDIGKAQPVKLAAMEAEFETHPAPAPFLPVAIPNTAEMKNDFAIEIPYLGGVIATRSIDKEIIGLKDLQALNETRVRSGIRAYELFTQLRAEKKANGQVNEETKAQFNEVKKDLGFGLLLKRYTNNVVDATEEQIKQAARDTIPNVGPNFWAFRAMIAAGGLIALLTFGAFVQNLRNKVTQIPLLLKVLLWGLPLPWIAIECGWFLAEYGRQPWATYEILPVGVSASNLSTGDLWFSIGLICALYLAFIIVEMYLMFKYARLGPSALKTGKYYFEQSAK", "output": "Probable cytochrome oxidase subunit."}]}
+{"id": "function_test_2316", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MYLDQIKSELVEAQDVLNKFISDENNIKLIQEAALLISNSFKQGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDASHLSCVSNDFGYEYVFSRYVEAVGQKGDVLFGLSTSGNSKNILNAIEAAKTKGMKVIAMTGKDGGKMAGLADVEIRVPHFRYADRIQEIHIKVIHILMMLIEFEMAKQA", "output": "Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate."}]}
+{"id": "function_test_2317", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDIKRIILYVIVALLAIALFNAWQRDYPPTPKPTPTVEQPTANGDHPTAYTPPAFTPGAAEKTKKAGTIAFTSKVPEARLITVRTDVLDVEIDTQGGNIVSAKLPKYPVSLEEKQTPVQILSGEPNELYIAQSGLTNGNGQPTTVQFESEKKQYVLENGQNQLIVQLTGRAPDGLLVTKTYTFHRDDYAIHLAYQVKNNTSKPWQGSLYTQITRRQPPTEHHHFYVRSYNGASMGSPQTPYEKLSYESLDKQNIDRTSQSGWIAMQQHYFLSAWVPGNPELTYHYYSHVIPASDEPNVYVVGFVSPQMNVAAGSEAATHATLYVGPEIAKRLKGLAPGLERTIDYGWLWPISMLLFWILSAVHAVVKNWGWSIIITTILIKIVFYWFSAKSFRSMARMREMQPRIQALKERHGDDRQALSRATMELYRKEKINPLGGCLPMLIQVPVFIAFYYVIIESVQLRQAPFIFWIHDLSVKDPYYILPIIMGLSMLAQQWVSPTSPDPTQQKMMWILPVIFTVFFINFPAGLVLYWITNNVVQTLQQWYVNKTYESHKAKLKARRARKRKR", "output": "Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins."}]}
+{"id": "function_test_2318", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQTHFIITSPLEQFEIVTIFPFSISGLNFSLTNSSLFLIIAVFLLLFWTSLSFYSNTLIPNNWQLVKESIYEITASMVQDNLGSKGEFYFPFIFTLHLLLLYCNLIGMIPYSFTVTSHIVFTFGLALSIFIGINLIGIQTHGFKFFALFLPRGVPLAIVPLLITIEFLSYIVKVFTLSIRLFANMTSGHTLLKIIAGFAWTMLSAGGLLAIFHLIPLALLLALTGLELAIAGLQAYVFTLLTCIYLNDVLDMH", "output": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane."}]}
+{"id": "function_test_2319", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDSSSYWSYDNIVPSFRLDGKLVIITGGSGGLSAVVSRALLAKGADIALIDMNLERTQQAARDVLQWGEEQMKGKHESPIGQVSAWSCNIGDAEAVELTFKAINEHHGKVASVLINTAGYAENFPAEEYPAKNAENIMKVNGLGSFYVSQAFARPLIQNNMTGSIILIGSMSGTIVNDPQPQCMYNMSKAGVIHLARSLACEWAKYNIRVNTLSPGYILTPLTRNVISGHTEMKTEWESKIPMKRMAEPKEFVGSILYLASDSASSYTTGHNLVVDGGYECW", "output": "Catalyzes the NAD(+)-dependent oxidation of D-arabinitol at carbon 4 to produce D-ribulose."}]}
+{"id": "function_test_2320", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAAELKSLLGKDVLFLKDCVGPEVENACANPAAGTVILLENLRFHVEEEGKGKDASGNKIKAEPAKIDAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLYDEEGAKIVKDLMAKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGTESSKKYAEAVARAKQIVWNGPVGVFEWEAFARGTKSLMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNV", "output": "Catalyzes one of the two ATP producing reactions in the glycolytic pathway via the reversible conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. In addition to its role as a glycolytic enzyme, it seems that PGK-1 acts as a polymerase alpha cofactor protein (primer recognition protein). May play a role in sperm motility."}]}
+{"id": "function_test_2321", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSETDSTDFHEMREPRIEKVVVHMGVGQGGVELQNAETILEAITGQQTVRTKAKSPEPEFGLRQGDPIGAKVTLRDDTAVDFLERALPAADLDRRQFDNTGNVSFGIEEHTDFPSQEYDPNIGIYGMDVTVNLTRPGYRVAKRDQGTRQIPSNHRLNSEDAVSFLVSNFDVEVNE", "output": "This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs."}]}
+{"id": "function_test_2322", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQAKIKNKRVLVKFSGEALAGDNQFGIDIHVLDHIAKEIKSLVENDIEVGIVIGGGNIIRGVSAAQGGIIRRTSGDYMGMLATVINAVAMQEALEHIGLDTRVQSAIEIKEICESYIYRKAIRHLEKGRVVIFGAGTGNPFFTTDTAATLRAIEIGSDLIIKATKVDGIYDKDPNKFKDAKKLDTLSYNDALIGDIEVMDDTAISLAKDNKLPIVVCNMFKKGNLLQVIKHQQGVFSMVK", "output": "Catalyzes the reversible phosphorylation of UMP to UDP."}]}
+{"id": "function_test_2323", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "QQDYTGWMDF", "output": "Hypotensive neuropeptide."}]}
+{"id": "function_test_2324", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSKIFKNRLEGLRALNRGVRALAKAVTSTLGPQGSHVVIKKDHSSPYVTKQGASIAKEIILPDAFENTGLKLIKEAALQMEAQVGDGSTTAIVLTDALFASGLKGVAVGLDPLEIKQGIQLAGAMLDEELAKLVVKISESEDIFHIATSSANHDAAIGKILADAIAQIGIEGVLSIKEGRGTETTLQATRHVGLNSGYLSSYFVTHPETMEVIYEDASILLCNQALSCLNQSFIHFLEQTFQTNRKPLIIIAEDFDPELLSILIVNKLKGNLPVCAIKAPGYGQQCKETLEDIAILTGATLVGDLLGISLSESSLDVLGRVEKIIVKRNTTIFSGGKGNQESLEQRIDYLRQAIVQSSSEMDTQDLEKRLARFVGGVAQIYLGSATENEYKERKIRLESALKAVKAAFKEGCLPGGGVALARAASIIKIPNELPIGVMFGCKCMLQSAEEPLRVLATNCGKDPEYVVDTVLKHADPYFGYNCINDSFENLITSGVFDPFSVTKCALKYSISISCLLLTSSFFIVDSSEKMQNPPLF", "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."}]}
+{"id": "function_test_2325", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAPNGTASSFCLDSTACKITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNSRNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINHISSWKAATIREHKATVTLAAVMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTGYQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTEVTAPQGATDR", "output": "The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway (By similarity)."}]}
+{"id": "function_test_2326", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNEKTIILANPRGFCAGVDRAISIVERALEEFGAPIYVRHEVVHNKFVVDNLREKGAVFIEDLAEVPPGATLVYSAHGVSKAVRQEAAERGFRVFDATCPLVTKVHKEVARLDAQDCEIIMIGHKGHVEVEGTMGQLAPGKMLLVETVGDVAKLEVRNPDKLAYVSQTTLSVDETKDIIAALNARFPNIRNPHKEDICYATTNRQTAVKELAEQCDIVIVVGSPNSSNSNRLREVAASRGIDAYMVDNAGYLQRAWFEGKNKVGVTAGASAPEVLVREVLATIRGWGHETVREGEGAEESIVFVLPKELRREGETKPDLCKR", "output": "Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis."}]}
+{"id": "function_test_2327", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCDQGYEVIVEQQIAHELQLKNVPTGTLAEIGQQADLAVVVGGDGNMLGAARTLARYDINVIGINRGNLGFLTDLDPDNALQQLSDVLEGRYISEKRFLLEAQVCQQDRQKRISTAINEVVLHPGKVAHMIEFEVYIDETFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRSDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKLF", "output": "Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP."}]}
+{"id": "function_test_2328", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MANLRKTHPLLKIANDALVDLPTPSNISAWWNFGSLLGLCLISQIITGLFLAMHYTSDISTAFSSVAHICRDVNYGWLIRNLHANGASFFFICLYLHIARGLYYGSYLYKETWNIGVVLFLLVMMTAFVGYVLPWGQMSFWGATVITNLLSAVPYVGDSLVQWIWGGFSVDNATLTRFFAFHFLFPFVVAGATMIHLLFLHETGSNNPVGLNSDADKIPFHPYFSYKDLLGFIIMLTALTMLALFYPNLLGDPDNFTPANPMVTPPHIKPEWYFLFAYAILRSIPNKLGGVLALLSSILVLMVVPILHTSKQRGLTFRPASQLLFWILVADMLVLTWIGGMPVEHPYIIIGQVASVLYFSLFLVLNPLVGWLENKMMNW", "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."}]}
+{"id": "function_test_2329", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MCDDDVAALVIDNGSGMVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNSPAMYVAIQAVLSLYASGRTTGIVFDSGDGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMSTAASSSSLEKSYELPDGQVITIGNERFRAPESLFQPSFLGMESAGIHETTYNSIMKCDVDIRKDLYANTVLSGGSTMFPGIADRMQKEITALAPPTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "output": "Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells."}]}
+{"id": "function_test_2330", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MESTLGSDLARLVRVWRALIDHRLKPLELTQTHWVTLYNINRLPPEQSQIQLAKAIGIEQPSLVRTLDQLEEKGLITRHTCANDRRAKRIKLTEQSSPIIEQVDGVICSTRKEILGGISSDEIAVLSGLIDKLEKNIIQLQTK", "output": "Transcription regulator that can specifically activate or repress expression of target genes. Required for expression of the virulence gene inv."}]}
+{"id": "function_test_2331", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNDSPGRTTVSGPSGGSDPFRVMVVDDSAVIRGLITRALESDPEIKVVASVANGQMAINTLSRQPIDVIVLDIEMPVLDGLSALPHLLQADPNVKIVMASTLTAKGADISLRALRAGAADYIPKPSSTRELTGADTFKRELTEKVKALGAAARRSGPRREGTAAARPPGAAAQPTSGYTLPSPVRAKPETGPLTVRPLPPDGRPDVIAIGSSTGGPQALFEVLGHLRGATQPILITQHMPATFTTILADHITRQCGIQCAEAKDGEPIVGGRAYVAPGDFHFLVVNRNGVPTVQLTKDAPENFCRPAVDPMLRSIVRQWGRRVLSVILTGMGHDGQKGCESVVQAGGVVIGQDEATSVVWGMPGAVATAGLCSAILPLKEIGPFIQKIAARRAA", "output": "Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid."}]}
+{"id": "function_test_2332", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEKSRQFDLAPYIDHAALDPATTREAIATCCAQALHHKFVAVCVYPSALSQAVELLRGKKVEICAVIGFPSGASTSGSKLYEAQEAAELGATELDVVINLGLLKDGNTEAVYNDIAPIVEATGLTVKAILEMGRLTESEKRLAAEICLDAGVQYLKTSTGWGKGATVADVRLLHQISQGRVGIKASGGIRTVEQAIALIEAGATRLGTSRGVELIQQQQQLWEQG", "output": "Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate."}]}
+{"id": "function_test_2333", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLNLVVNREIAFSLLPLLHQFDRKLLEQFFADGLRLIHYDVMDHFVDNTVFQGEHLDELQQIGFQVNVHLMVQALEQILPVYLHHQAVKRISFHVEPFDIPTIKHFIAQIKQAGKQVGLAFKFTTPLVNYERLVQQLDFVTLMSVPPGKGGQAFNSAVFNNLKQAHKYHCSIEIDGGIKLDNIHQIQDDVNFIVMGSGFIKLERWQRQQLLKTNQ", "output": "Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate."}]}
+{"id": "function_test_2334", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTMTTTNYGADQIQVLEGLEPVRKRPGMYIGSTGPKGLHHLVYEVVDNAIDEALAGYCTHIEIDINADGSVTVVDNGRGIPTDIHPTTGRSALETVLTVLHAGGKFGGGGYKVSGGLHGVGVSVVNALSEWVEVKVWRQGKEHFQRFERGNPIGTLEATPNEGHSTGTQVSFLPDTQIFKDGIEFDYHTLASRLKELAYLNAGVRITFGDRRADSLKEEQFYYEGGIREYVTYMTTDKTPLHEEIIYTSGEKNDVQVEVALQWCVDAYSDTLLGFANNIRTIDGGTHLEGLKAVLTRTLNSVARKRNKLKDGDSNLGGENIREGLTGVISVKVPDPEFEGQTKTKLGNTEVRGIVDTLVGEALTEFLEFNPGVADAIIEKAVQAFKAAEAARRARELVRRKSVLESSTLPGKLADCSSKDPSESEIFIVEGDSAGGCFSGDTLVALTDGRSVSFEQLVEEEKQGKQNFCYTIRHDGSIGVEKIINARKTKTNAKVIKVTLDNGESIICTPDHKFMLRDGSYKCAMDLTLDDSLMPLHRKISTTEDSGITIDGYEMVWSPRSDSWLFTHLVADWYNRWQGIYIAEEKQHCHHKDFNKRNNNPDNLIRLSPEKHLALHRKHISKTLHRPDVVEKCRRIHQSPEFRRKMSARMQSPETRAILSKQAQAQWQNETYKLTMMESWRSFYDSNEDYRQQNAEQLNRAQQEYWAQAENRTAQAERVRQHFAQNPGLRQQYSENAVKQWNNPELLKWRQKKTKEQWTPEFREKRREALAQTYYRKTLAALKQVEIENGYLDISAYDSYRISTKDKSLLRFDRFCERYFENDENLAREAVLNYNHRIVNIEAVSETIDVYDIEVPHTHNFALASGVFVHNSAKQGRDRRFQAILPLRGKILNIEKTDDAKIYKNTEIQALITALGLGIKGDDFDISSLRYHRVVIMTDADVDGAHIRTLLLTFFYRYQRDLVDQGYIYIACPPLYKLERGKNHFYCYSDRELQEQISQFPPNANYTIQRFKGLGEMMPQQLWDTTMNPESRTMKRVHIEDAAEADRIFTVLMGDRVAPRREFIETYGTKLDLTDLDI", "output": "A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner."}]}
+{"id": "function_test_2335", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "QGRPPGPPIPP", "output": "This peptide both inhibits the activity of the angiotensin-converting enzyme (ACE) and enhances the action of bradykinin by inhibiting the peptidases that inactivate it. It acts as an indirect hypotensive agent."}]}
+{"id": "function_test_2336", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNAHGLSTEKAAAFTRRLRAEPQFLLAQNVATCSDPLEVCLQRQVVQDTIQVFQHAVPAEGKPVTNQKNSGRCWIFSCLNAMRLPFMKKYNIEEFEFSQSYLFFWDKVERCYYFLNAFVETAQKKEPIDGRLVQFLLTNPTNDGGQWDMLVNIVEKYGVVPKKYFPESHTTEATRRMNEILNHKMREYCLRLRNMVATGTNKEELCAAMDTMIEEVFRIVSTCLGNPPETFCWEFRDKEKNYHKFGPMTPVQFYNEHVKPYFNMEDKVCLVNDPRPQNPYCQLYTVEYLGNMAGGRKTLYNNQPIEVLKKLAATSIKDGEAVWFGCDVAKHFYSKLGINDLNIFNHELVFGVSVKNMNKAERLIFGDSLMTHAMVLTAVSEKDGQEDCYEKWRVENSWGEDRGNKGYLIMTDDWFSEYVYEVVVDKKYVPEDVLAVMEQEPIVLPAWDPMGALAK", "output": "The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity."}]}
+{"id": "function_test_2337", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNESLFTPFITPTVLGLPAAVLVILFPPLLIPTSKHLINNRLIIIQQWLIRLILKQMMTTHNAKGRTWSLMLTSLIIFIASTNLLGLLPYSFTPTTQLSMNLAMAIPLWASTVAMGLRFKAKITLTHLLPQGTPTPLIPMLIIIETVSLFIQPLALAVRLTANITAGHLLMHLIGSSALAMLAINLPLTLITLTILTLLTILETAIALIQAYVFTLLVSLYLHDNS", "output": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane."}]}
+{"id": "function_test_2338", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNNAKMWLVVKPTVGIPLFLVACAIASFLVHLMLVLTTGWMGDYYSGSFEAASLVSNATTLLS", "output": "Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers."}]}
+{"id": "function_test_2339", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAHPAQLGLQNATSPIMEELIAFHDHALMIIFLISSLVLYIISLMLTTKLTHTSTMNAQEIEMVWTILPAIILIMIALPSLRILYMTDEFNKPYLTLKAIGHQWYWSYEYSDYVDLAFDYYITPTYFLEPGEFRLLEVDNRTTLPMEADIRMLISSQDVLHSWAVPSLGVKTDAIPGRLNQAMLASMRPGLFYGQCSEICGSNHSFMPIVLEFIYFQDFEVWASYLYIVSL", "output": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix."}]}
+{"id": "function_test_2340", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTRLVLGSASPGRLKVLRDAGIEPLVIASHVDEDVVIAALGPDAVPSDVVCVLAAAKAAQVATTLTGTQRIVAADCVVVACDSMLYIEGRLLGKPASIDEAREQWRSMAGRAGQLYTGHGVIRLQDNKTVYRAAETAITTVYFGTPSASDLEAYLASGESLRVAGGFTLDGLGGWFIDGVQGNPSNVIGLSLPLLRSLVQRCGLSVAALWAGNAGGPAHKQQ", "output": "Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids."}]}
+{"id": "function_test_2341", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRALVTGAAGFIGSTLVDRLLADGHSVVGLDNFATGRATNLEHLADNSAHVFVEADIVTADLHAILEQHRPEVVFHLAAQIDVRRSVADPQFDAAVNVIGTVRLAEAARQTGVRKIVHTSSGGSIYGTPPEYPTPETAPTDPASPYAAGKVAGEIYLNTFRHLYGLDCSHIAPANVYGPRQDPHGEAGVVAIFAQALLSGKPTRVFGDGTNTRDYVFVDDVVDAFVRVSADVGGGLRFNIGTGKETSDRQLHSAVAAAVGGPDDPEFHPPRLGDLKRSCLDIGLAERVLGWRPQIELADGVRRTVEYFRHKHTD", "output": "Involved in the metabolism of galactose. Catalyzes the conversion of UDP-galactose (UDP-Gal) to UDP-glucose (UDP-Glc) through a mechanism involving the transient reduction of NAD (By similarity)."}]}
+{"id": "function_test_2342", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKTWPAPTAPTPVRATVTVPGSKSQTNRALVLAALAAAQGRGASTISGALRSRDTELMLDALQTLGLRVDGVGSELTVSGRIEPGPGARVDCGLAGTVLRFVPPLAALGSVPVTFDGDQQARGRPIAPLLDALRELGVAVDGTGLPFRVRGNGSLAGGTVAIDASASSQFVSGLLLSAASFTDGLTVQHTGSSLPSAPHIAMTAAMLRQAGVDIDDSTPNRWQVRPGPVAARRWDIEPDLTNAVAFLSAAVVSGGTVRITGWPRVSVQPADHILAILRQLNAVVIHADSSLEVRGPTGYDGFDVDLRAVGELTPSVAALAALASPGSVSRLSGIAHLRGHETDRLAALSTEINRLGGTCRETPDGLVITATPLRPGIWRAYADHRMAMAGAIIGLRVAGVEVDDIAATTKTLPEFPRLWAEMVGPGQGWGYPQPRSGQRARRATGQGSGG", "output": "Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate."}]}
+{"id": "function_test_2343", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVQDTEVVEAGTSKETETTVDVEKEIQECMGAGKKDLLCNDYSEAVNCFQEACTLLSGKHGQMAEECCEAYYYYGVSLLELARLENGVLGNALKGVPEEDADGDSDQEQEQFEKPDLPETEREKLREEVEAAMATEDEDTQEERGCPRRVEKKKEDDKPKESEKSAEKSDEKEKEEKQAKVESSTVKDVKDEKSSDKPVESSNTEEPGTSGTSASSSKENESEEDPDDISNMQLAWEMLELAKVLYKKHDKSKTNKQMVAQCHLKLGELGLEVENHPQAIGDFLECLVIQKDLLPETDRKLAETYYNLGLAYSFEKRYDNALEHYQSALDVLEARVDMLNELIESNEGNKEKEKEIISECKEVGELKELIPDINSKIEDVILAKKQMQKLDGSPFRQASEGESSSGLGASTSDDKPCSTIPIRKVAPTSVPVAKDSPSDITHLVRRKRPSPDEDNQPAESKENESKKAKQEETEEATNGHSAVKKDTDVTDKNGTNGHSKTPKKDAAKRR", "output": "May function as a nucleosome assembly factor during rapid embryonic cell divisions."}]}
+{"id": "function_test_2344", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAIERITDNKFELVSKYDPAGDQGQAISELVENIENGEKAQILRGATGTGKTYTMSQVIAQTGKPTLVMAHNKTLAGQLYSEFKEFFPNNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYQDSVVSLRPGQEISRDQLLNDLVGIQFERNDIDFQRGCFRVRGDVVEVFPASRDEHAFRVEFFGDEIDRIREIEVLTGQVLGEVDHLAIFPATHFMTNDDRMEESIAKIEAELEAQLKVFRSEGKLLEAQRLEQRTNYDIEMLREMGYCNGVENYSRHMDGREEGEPPYTLLDFFPDDFMIMIDESHMTMGQVKGMYNGDRARKEMLCNYGFRLPSALDNRPLKREEFESHVHQIVYVSATPGDYEMEQTDTIVEQIIRPTGLLDPVVEVRPMMGQIDDLVGEIHKRAEKNERVFVTTLTKKMSEDLTAYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVILYSDMAKALDENDPADKEILDSGYYTEYEGQKYKITRSMKHAMDETARRRDIQMAYNEEHGITPQTIKKEIRDLIAITKKTDSGELEEVDASAMNKKERKALVKKLEKEMQQAAAALDFEGAAQLRDMVLELRAMD", "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage."}]}
+{"id": "function_test_2345", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKEIVDAYFKKYGIVNHQLDSMNSFYATPDNPNSVMQQIVDETKVSDDADPGYFVLDPAKTGGHDIRIYYGRVRENGHYVGEQTIFIGKPEIKEASGASNQITPNEARLRDLNYLAPVTLKLRIVEDGIEKGSEIIKVGDLPVMVRSKICTLSEENLDQYIEKNNGPIGLSRREKLQYVGEDPDDPGGYFIIGGSERVIVSLEDLAPNKIMVEWEDRYESKVEVSKVFSQRGGFRALTSMEKGTDGTINVSIPSVAGTVPLVILMKALGLERDVDVHDAIASVPEMEPIIYSNIEDSKNPKVLPPNGVNTTEDAISYLEKRFAAGQAKEFRDKKISQMLDHSLLPHLGDSPSDRIRKAIYLGRMARSLLELSLGIRKEDDKDHLANKRIKLAGDLMDELFRSAFQSVMKDLKYQLEKTYNRKRGIKIRPAVRQDLLTQRVLHAMSTGNWIGGRTGVSQLLDRVSNLSTISHLRRIISPLTRTQPHFEARDLHPTQWGRICPNETPEGQNCGLVKNAALLINVTQGIDPDSVMEILKGMDVREVLEESPKKGRVYLNGDFIGYHDDPRYLVSRIREERRSGRMSDEVNVRYDDNTNEVIVNSDRGRLRRPLLILKDGKTVLDRTMIERLKHGEISFEDLVKQGAIEWLDAEEEEDTYVAVYAYDIPEKCPHCNSYLYRSMVDWVNPGESEITLECGFCHQRFNVPSKLSKENTHLEIDPAMILGVVASIIPYPEHNSSPRITIASAMAKQSLGFAQSNVRIRPDTRGHLLHYPQVPLVRTRVMDYIHYDRRPAGQNFVVAVLSYEGYNIQDALVINKAAIERGLGRSTFFRTYSAEERRYPGGQEDKFEIPTHDIIGARAEEYYKNLDDSGIIFPEAYVEGSDVLIGKTSPPRFLEEGEERLGPQRRRESSVTMRPNESGYVDNVFLTVSESNSRVVKIKVRSERIPELGDKFASRHGQKGVVGLVVPQEDMPFTEDGIIPDLIFNPHSIPSRMTVGHILEMIGGKIASRTGRFIDGTIFSGEPEKSLRDALVKYGFRKSSTEVMYDGITGRRFKADIFVGVIYYQKLHHMVAGKFHARSRGPVQILTRQPTEGRSRQGGLRFGEMERDTLIAHGAAMVIKDRLLDQSDGTVLYVCGNPSCGHIAIYDRRKGTLRCPVCGNTGNIYPIETSYAFKLMRDELISLGVVMRLMLGDMK", "output": "DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit is involved in DNA promoter recognition."}]}
+{"id": "function_test_2346", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQFSLIPFISSFALTVIFLPLFIGFMRMKHEGQVIRDEGPKWHEKKSGTPTMGGVVFMLASVISTLWVLIWQKNLNKTTWILIIAFLGYGIIGFLDDGIKLYFKRNLGLKAWQKLLGQIIIAALIIALAFSDHFAFELYIPFAGMVRNSFLFSLFVLFWLVGFSNAVNLSDGLDGLATGLSIIAYATYAWIAYQEKNWVIVAFTLSVIGGLVGFFIFNHKPAKIFMGDAGSLALGGGLATVSIFLHRPWSLLLIGIVFVLETLSVILQVISFQTTGKRIFKMTPIHHHFEMLGWSEWKVDIVFWIVGLIGSIIYLIIWG", "output": "Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I."}]}
+{"id": "function_test_2347", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTIALGKFTKEENDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFALGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDLTRWCQLGGLWTFVALHGAFGLIGFMLRQFELARSVQLRPYNAIAFSGPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL", "output": "Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors. D2 is needed for assembly of a stable PSII complex."}]}
+{"id": "function_test_2348", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSQRKIIHVDMDAFYASVEQRDRPGLRGRPVVVGGDPNGRGVVAAASYEARRHGIHSAMPAWRAARLCPDAVFLRPRFDVYRSISAQIQALFREYTPLVEPLSLDEAYLDVSDCPRRGGSATLIAREIRARIHEQTGLTASAGVSCNKFLAKIASDLDKPDGLHVIPPEQAEAFVAALPVGKIHGVGQATRQRMERMGVRTGADLRRLTLLELQRAFGSRARFYYELARGRDERPVRPRRERKSVGAETTFGEDLNNPAEMLERMAPLADKVAASLHRRGLAGRTVTLKVKYHDFRQITRSLSGRPVQSADEIRARLPALLQDTEAGDRPVRLLGVTVSGLVTVTPDQARQLALF", "output": "Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII."}]}
+{"id": "function_test_2349", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MADNKLHIFAVSDSVGETAEKIAVASVLQFNLDRNITRFSRVTKEEQVEKIIDQAVENDAIIIYTIVKPELSRFLDETARIKQVIAVNVMAPLFDAIQFKTGQKPEYITGLTHKMDDQYFNRMKAIEYTIEHDNGQNLDSVHEADLIVLGLPRTSKTPLSMHLANLGIKVANYPILMDTEIPQEIVDLKGRIPMVGLTIDIDTLMELRKERFRSFELPDDIETLDDLVAEELDNAYRIYAKLKCLVIDVTLDDIEEVGNTITHKFNLPLRITHHRF", "output": "Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation."}]}
+{"id": "function_test_2350", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKTTFLDFEQPIAELEAKIEELRFVQDDSAVDISEEIERLSKKSQQLTKDLYANLSPWQVSQIARHPQRPYTLDYVAELFTDFHELHGDRAFADDLSIVGGLARFGGHPCMVIGHQKGRDTKERAARNFGMPRPEGYRKAERLMRLAEKFGLPIFTFVDTPGAYPGIGAEERGQSEAIGRNLYVMAELKTPIITTVIGEGGSGGALAIAVADTVMMLQFSTYSVISPEGCASILWKSAAKAPEAAEALGLTAHRLKALGLIDKIINEPLGGAHRDPKGMAALLRRALADSLRQFQGMSIDALRERRFERLMAYGKFKETTPGA", "output": "Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA."}]}
+{"id": "function_test_2351", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRNITNFLKTFLLWELLKGLKVTGKHFFTRKVTVQYPDEKTPISNRFRGLHALRRYENGEERCIACKLCEVVCPALAITINSTEREDGTRRTSSYEMDLFKCIFCGYCEESCPVDSIVETNILEYHFEERGENIMTKAKLLAIGDKYEAQIAADRLQDKDFR", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_2352", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNLAAMDPTTYDAQLTAKRIKLEQAFAQFETPSVEVFASEPAHYRMRAEFRVWHEGDDLYYYMFDKVLNDKVRCDQYLPASALINQMMAALIAELKPNHSLRHKLFQVDFLSTLSGEILVSLLYHRQLDDQWRSEAAALKARLSSQFKVNIIGRARKQKIDLDKDFVVESLQVNDKVFHYKQIENSFTQPNAKVAIKMLEWAIDVTQNSQGDLLELYCGNGNFSIALAQNFNRVLATELAKPSVDAAQYNIEVNNIDNLQIIRMSAEEFSDAMAKKRSFRRLEGIDLDSYVCNTIFVDPPRAGIDPATLELVQGYERILYISCNPDTLKDNLQQLNQTHKVTRFALFDQFPYTDHMETGVLLERR", "output": "Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA)."}]}
+{"id": "function_test_2353", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTVRVRLAPSPTGTLHIGTARTAVFNWLFARHQNGKFLLRIEDTDKERSKPEFTENILDGLRWLGLDWDEEPVIQSERIEVHRQAISQLLAQGLAYRCYVSEQELDAMREAQRASGQPPRYDNRHRHLTGDQEEAYRAEGREAVIRFRIDDEATIAWTDMVRGPMQWRGADLGGDMVIARRAPATTVGDPLYNLVVVVDDAAMAISHVIRGEDHIANTAKQLLLYQALELNCPTFAHTPLILNPEGRKLSKRDGVTSIGDFQEMGYTAEALANYMTLLGWSVPEGTEERFTLRQAAEVFSFDRVNKAGAKFDWDKLNWLNAQVLHGWSPAELLAALEPRWQKQGWVVSDPLWANDLAVLLGPSLTLIEDGVTQARPFFEEPPLEEDGLKQLEQEGARPALQALLSALELNAWDGLDVERAQTLLKEAAASAEVKKGVLMKSLRAALLGRLQGPDLITTWALLARLGHDRQRLRRCL", "output": "Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)."}]}
+{"id": "function_test_2354", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLRTHLAGSLRAEQAQQTVTLTGWVARRRDHGGVIFIDLRDASGVSQVVFREGAAAEQAHRLRAEYCVKVTGVVEVRPEGNQNFEIPTGAIEVNVTDLEVLNESAPLPFQLDDQAGEEARLKYRYLDLRREGPGHAIRLRSKVNAAARAVLAHHEFVEVETPTLTRSTPEGARDFLVPARLQPGSFYALPQSPQLFKQLLMVGGIERYYQIARCYRDEDFRADRQPEFTQLDIEMSFVNQDDVILLAEEVLSSLWKLVGHEIKTPIARMTYAEAMRRYGSDKPDLRFGVELVECAEFFKDTTFRVFQQEYVGAVVMPGGASQPRKQLDAWQEWAKQRGAKGLAYVLVGEDGTLGGPVAKNLTDTEREGLAAHVGAKPGDCIFFAAGTTKSSRALLGAARGEIARKQNLIDPDAWAFVWVVDAPLFEPTADATASGDVALGYSAWTAVHHAFTSPKPESIDTFDTDPGSALAYAYDIVCNGNEIGGGSIRIHRKDIQERVFKVMGISHEEAEEKFGFLLDAFAFGAPPHGGIAFGWDRITALLAGVDSIREVIAFPKSGGGVDPLTNAPAPITAQQRKESGVDAKPEPKGDAASAKPDAPADK", "output": "Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn)."}]}
+{"id": "function_test_2355", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTDIHAQRILILDFGSQYTQLIARRVREIGVYCEIRAFDMTAEELAEFAPKGIILSGGPESVTAAQTPRAPQAVFEAGIPVLGICYGMQTMAEQLGGKVIAGEKHEFGYARVEKAEPNALLDGIVDHEEQGKEFLDVWMSHGDRVGEMPAGFVATATTGSCPIAGMANDEKRFYGIQFHPEVTHTLQGGRLLERFIRELCECEALWTPSNIISDAIDTIREQVGTDEVILGLSGGVDSSVVAALLHKAIGDQLTCVFVDNGLLRHQEGDQVMEMFADNMGVKVIRVDAEDNFLGKLAGEADPEKKRKIIGNTFIDIFDDEASKLQNANWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPEDMKLKLVEPLRELFKDEVRKIGLELGLPYDMVYRHPFPGPGLGVRILGEVKKEYADTLRLADHIFIEELRAAGLYHKTSQAFAVFLPVKSVGVVGDARRYEYVVALRAVETIDFMTARWAHLPYDFLELVSSRIINEIPGISRVTYDISSKPPATIEWE", "output": "Catalyzes the synthesis of GMP from XMP."}]}
+{"id": "function_test_2356", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSTANNNQPESISMNAFKQPKAFYLIFSIELWERFGYYGLQGIMAVYLVKMLGMSEADSITLFSSFSALVYGFVAIGGWLGDKVLGAKRVIVLGALTLAVGYSMIAYSGHEIFWVYLGMATIAVGNGLFKANPSSLLSTCYSKDDPRLDGAFTMYYMSINIGSFFSMLATPWLAAKYGWSVAFSLSVVGMLITLVNFWFCRKWVKNQGSKPDFLPLQFKKLLMVLVGIIALITLSNWLLHNQIIARWALALVSLGIIFIFTKETLFLQGIARRRMIVAFLLMLEAVIFFVLYSQMPTSLNFFAIHNVEHSIFGIGFEPEQFQALNPFWIMLASPILAAIYNKMGDRLPMPHKFAFGMMLCSAAFLVLPWGASFANEHGIVSVNWLILSYALQSIGELMISGLGLAMVAQLVPQRLMGFIMGSWFLTTAAAALIAGKVAALTAVPSDAITDAHASLAIYSHVFMQIGIVTAIIAVLMMLTAPKLYRMTLAPSDHNDVKIMTQ", "output": "Proton-dependent permease that transports di- and tripeptides."}]}
+{"id": "function_test_2357", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEKIHATTVVAIRHNGQISIGADGQATLGNTVVKDYVKKVRKLMEGKVLCGFAGSTADAFTLLERFEEKLNTYAGNMKRAAIELAKDWRTDRYLRKLEAMMIVVNKDELLLISGTGDVIEPDNDILSIGSGSMYAQSAAAALKKHATHLSAPEMVRESLSIAADICIYTNHNFVIETAVA", "output": "Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery."}]}
+{"id": "function_test_2358", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKFVDEAFIDIAAGDGGSGCVSFSHEKYKEFGGPNGGDGGRGGHVYAVADVNLNTLVDFRFSRRHEARNGQHGMGSDMFGAKGDDIILKMPVGTILTDAETGEVLFELLVPGEQVLIAKGGDGGFGNLRFKSSTNRAPRSKTPGWPGERKNLKLELKVLADVGLLGMPNAGKSTFISAVSNARPRIADYPFTTLHPNLGVVRVGPEQSFVVADLPGLIEGASEGAGLGHLFLRHLQRTRLLLHIVDLAPFDEGVDPVAQAKAIVRELKKYDEALYEKPRWLVLNKLDMVDADKRAAIVKDFVKRFKFKGPVFEISALTREGCEHLIKTIYQHVKQVQKSEQPVEEVDPRFVPLPPESPETP", "output": "An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control."}]}
+{"id": "function_test_2359", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTTTTVTSTPLAEKTVLAPKAELHIHIEGSLEPELIFALAERNGVKLAYDSIDALRAAYAFTDLQSFLDIYYAGASVLLHEQDFYDMTMAYVERCLADNVVHSEIFFDPQTHTERGVPIATVVAGIERALADAEQRGMSSKLILCFLRHLSEEDALATFEEARPLFEQYRHRLIGVGLDSSERGHPPSKFERVFAKARSLGLKLVAHAGEEGPPSYIYEALDLLKVDRVDHGVRSIEDPALVTRLADSRVALTVCPLSNLKLCVFDDLTKHTLKDLLDRGVAVTVNSDDPAYFGGYVNANYLATIDALKLNDAEVYTIIRNSFEASFVTPGQRSELIAKLDAHWHPGGPH", "output": "Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism."}]}
+{"id": "function_test_2360", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLLVMDMGNSHIHIGVFDGDRIVSQIRYATSSVDSTSDQMGVFLRQALRENSVDLGKIDGCGISSVVPHLNYSLGSAVIKYFNIKPFFISMDTTDLDMSAVEAHQVGADRIASCISAIADHPNKDLLIIDLGTATTFDLVTKDKKYLSGSIMPGVKLSLNALCQGASQLSSVTIVKPEVAIGYDTKTNIRSGLYYGHLGALKELKRRSVEEFGSPVYTIATGGFAGLFKEEDIFNEISPDLILRGIRIAFLENNKKGV", "output": "Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis."}]}
+{"id": "function_test_2361", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTKKLFIKTWGCQMNEYDSQKMADLLDSTHGYQVADTAEEADIILLNTCSIREKAQEKVFHQLGRWKNLKQDKPELIIGVGGCVASQEGQVIRQRAPFVDLVFGPQTLHRLPEMINQIKGGSSSVIDISFPEIEKFDRLPEPKAEGPTAFVSIMEGCSKYCTFCVVPYTRGEEVSRPVDDVLLEVAQLAEQGVREVNLLGQNVNAFRGPHHDGAICTFAELLEMVASIDGIDRIRYTTSHPVEFTDDIIDAYATIPELVDHLHLPVQSGSDRVLNLMKRGHTAIEYKSKIRKLRKIRPNLSMSSDFIIGFPGETDDDFEATMDLIQAMDFDLSFSFIYSARPGTPAADLPDDVSETTKKERLQLLQNRITQQALRIARNMIDSEQRVLVEGPSKKNPMELSGRTENNRVVNFEGTPDMIGGFVDVKITDVFANSLRGDVLRKEADMNLRINVAPQAILAKQTNKTDALGVAQFVPAH", "output": "Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine."}]}
+{"id": "function_test_2362", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MHTKAVYPGTFDPITNGHADLIERAANMFAHVIVGIAANPSKKPLFSLQERVDLIKEVTEHLPNVEVIGFEGLLADFADSQGATVLIRGLRAVSDFEYEFQLANMNRRLNPNLESIFLTPAEENSFISSTLVKEVALHRGKVDQFCHPAVQAALKEKLQQ", "output": "Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate."}]}
+{"id": "function_test_2363", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLATDSDPIVAIATAAGRGGIGVVRVSFGRGGEAAALPLIDALCGQKLAPRHASYVPFLDAHGAPLDRGIALYFPAPHSYTGEHVLELQGHGGPIVMQLLLQRCLDAGRGFGLRLAEPGEFTRRAFLNDKLDLAQAEAVADLIEASTEAAARSAGRSLDGAFSRQIHALVDDVITLRMLVEATLDFPEEEIDFLEAADARGKLAKIRAQLAHVLGDARQGALLREGLSVVLAGQPNVGKSSLLNALAGAELAIVTPIAGTTRDKVAQTIQVEGIPLHIIDTAGLRETEDEVERIGIARTWSEIERADVVLHLLDSRTGMTADDETIAARFPAGVPVVRVLNKTDLTGVPACVEHPAAEGDLTEVHLSAKRGDGIDMLRAELLRIAGWQAGAEGVYLARERHLIALRAAQEHLAQAANHAEQRAQSLDLFAEELRLAQEQLNAITGEFTSDDLLGVIFSRFCIGK", "output": "Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34."}]}
+{"id": "function_test_2364", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKIKTRFAPSPTGYLHVGGARTALYSWLFSRHLGGEFVLRIEDTDLGRSTQEAIDAIMDGMNWLNLDWDEGPYFQTKRFDRYNAVIDQMLDAGTAYRCYCSKERLEALREAQMANGEKPRYDGHCRDSQCTHGADEPSVVRFRNPQEGSVIFDDKIRGPIEFSNQELDDLIIRRTDGSPTYNFCVVIDDWDMEITHVIRGEDHINNTPRQINILKALGAPVPEYAHVSMILGDDGKKLSKRHGAVGVMQYRDDGYLPEALLNYLVRLGWSHGDQEIFSIEEMTQLFTLDAVSKSASAFNTEKLQWLNHHYINSLPPEQVAVHLSWHVEQLGIDTRNGPELVEIVKLLGERCKTLKEMAESCRYFYEEFDAFDVDAAKKHLRPIARQPLEAVKVKLAAITEWTTENVHNAIQGTADELGVGMGKVGMPLRVAVTGVGQSPGMDVTVHAIGQARTLARIDKALAFISEREAQQ", "output": "Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)."}]}
+{"id": "function_test_2365", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTSNPPDLRPDLAPKPTFGTAPRPDQPTLGMVSLGCPKALVDSERILTRLRAEGYGISADYAGADAVIVNTCGFLDSAKAESLEAIGEALKENGKVIVTGCLGAEPDYIREHHPRILAVTGPHQYEQVLDAVHAAVPPSPDPFVDLLPATGVSLTPRHFSYLKISEGCNHKCKFCIIPDMRGKLASRPAHAVLREAEKLVTAGVRELLVISQDTSAYGLDRKYDVNPWKDGEVRSHITDLSRALGELAPADQLWVRLHYVYPYPHVRELIPLMADPENAVLPYLDIPFQHAHPDVLRRMARPAAAAKTLDEIRAWRAICPDITLRSTFIVGYPGETEAEFQHLLDWMDEAQLDRVGCFKYENVDGARSNDLPDHVAEEVKQNRWERFMEKAQAISEAKLASKVGQTLQVIVDEIDEDGIATCRTKADAPEIDGNLFIDEGTANLSVGDLVTVEVDEAGEYDLWGALR", "output": "Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12."}]}
+{"id": "function_test_2366", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MADAVILGIESSCDETAAAVIRNGAEILSSVVFSQIYTHMRYGGVVPELASREHLKAIVPVVRQAVEDAGQSYDKIDAIAVTRGPGLAGALLVGVSYAKALSFALDKPLIGVNHLEGHIHVVLLEQKQQGVGEIQFPVLALVVSGGHTHLYLAEKKDAGWTYRDVGHTRDDAAGEAYDKVAKLLGLGYPGGPILDGLAKHGDPRAVRFPFAQIKHRDRNPQNRHEDDDARVDFSYSGIKTAVLRYVETHEMKAAIEARRTALKEIEKPSQDDYLRVCDRQTLDLIASFQRAVVNDLVSKALHAAAENNAATLLVTGGVAANSELRETFERRAGELGLPVYFPSRPLSTDNAAMIAAAAYPRFLSGEFAAPDLSAEANLRLR", "output": "Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction."}]}
+{"id": "function_test_2367", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MINLLFAVIAYLIGSVSFAVVVSKVMGLPDPHSYGSGNPGATNVLRTGNKKAAIFTLIGDALKGLAAVLLAKHFGPAYGVDETGIALVALAVFLGHLFPLYHRFAGGKGVATAAGILFAIDPILGAGTLATWLIIAFFFRYSSLAALISAIFAPFFYVLMNGVDIMAGAILVISVLLIARHRANIAKLLAGKESRIGEKKKV", "output": "Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP."}]}
+{"id": "function_test_2368", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSTAQSDALTFECETGNYHTFCPISCVSWLYQKIEDSFFLVIGTKTCGYFLQNAMGVMIFAEPRYAMAELEEGDISAKLNDYGELRRLCLQIKKDRNPSVIFWIGTCTTEIIKMDLEGIAPKLEAEIRVPIVVARANGLDYAFTQGEDTVLAAMAQRCPLNLKNQSDNTSLKTSPHIPLVLFGSLPDPVVTQLTMELKKQGIFVSGWLPSKRYTELPVIKEGYYVAGVNPFLSRTATTLMRRRKTKLIGAPFPIGPDGTRAWIEKICSVMNVKPIGLEDREKAIWASLEDYISLIRGKSVFFMGDNLLEVSLARFLTRCGMTVYEIGIPYMDKRYQAAELALLKATCDKMNVMMPTIVEKPDNYNQVDRIRDLKPDLVITGMAHANPLEARGINTKWSVEFTFAQIHGFTNARDILELVTRPLRRNLSLSELGWDVYSKQS", "output": "Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (ChlN-ChlB) is the catalytic component of the complex."}]}
+{"id": "function_test_2369", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGKEKEHLNLVVIGHVDSGKSTTTGHLIYKLGGIDARTIEKFEKESAEMGKASFKYAWVLDKLKAERERGITIDIALWKFETENRHYTIIDAPGHRDFIKNMITGTSQADAAILIIASGTGEFEAGISKEGQTREHALLAYTMGVKQMVVAMNKMDSTEPPYSEDRYEEIKKEVSTFLAKVGYKPAKMNFVPISGFQGDNIQENSTNMPWYKGPTLCAALDSFKIPKRPIAKPLRLPLQDVYKIGGIGTVPVGRVETGVLKAGMVITFAPKGCSAECKSVEMHHEEVPEAAPGNNVGFNVKGLSVKDIKRGFVASDSKNDPATDTESFVSHTIVMNHPGEIKAGYTPVIDCHTAHIACKFEELLTKADKRSGKMTEENPKFLKAGDAGLIRLSPSKPLCVETFATYAPLGRFAVRDMRQTVAVGVIQEIKKKATEDKKGKKK", "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."}]}
+{"id": "function_test_2370", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MANIDNKEQTELDQQDMEDVEDIEEEEAGEDANSKARQLTAQMMQNPQVLAALQERLDDLVGTPTGYIESLPKVVKRRVNALKNLQVKCAQIEAKFYEEVHELERKYAALYQPLFDKRSDIINATYEPTEEECEWKVDEEEDISGDLKDKAKLEEEKKDEEKEDPKGIPEFWLTVFKNVDLLSDMVQEHDEPILKHLKDIKVKFSEAGQPMSFTLEFHFEPNDFFTNEVLTKTYKMRSEPDESDPFSFDGPEIMGCTGCLIDWKKGKNVTLKTIKKKQKHKGRGTVRTVTKTVPNDSFFNFFSPPEVPENGELDDDAEAILTADFEIGHFLRERIIPRSVLYFTGEAIEDDDDDYDEEGEEADDEEGEEEADEDNDPDYEPKKDQNPAECKQQ", "output": "Acts as a chaperone for the linker histone to facilitate deposition of histone B4 onto linker DNA. Required for both remodeling of sperm chromatin into nucleosomes, and linker histone binding to nucleosome core dimers. Plays a role in tissue-specific gene regulation. Required for primitive hemopoiesis, acting upstream of tal1/scl (By similarity)."}]}
+{"id": "function_test_2371", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSAAKNEMYYSLLEWFKTLNLNAPHADAESLADGVAVAQALNQFAPESFTDSWLAKIKASAVGINWRLRMSNLKKVTQSLYDYYSEVLNYTLSDFVKPDVQRIAEKCDLVELERLLQLVLGCAVNCAKKQSYITEIMCLEEELQANIMRALQELESSRNAAEGGIVTSLSRSSISGMLDGKVLQEERDAMAQKCFETEKKMLLLIDEKTNLQQELQRVQKEFARLEHSSTVIGDDGVSLGPVQTGSVRYNELRRQLDLLKEELLQSEGAREDLKLKAQQQETDLLHMQMRIDELLKSTAEVTTLKDEVDVLRESNDKLKICEGQLDTYKKKLEDYNDLKKQVKILEERSADYVQQNAQFEEDAKRYANTKGQIELFKKEIQDLHTKLDSESSKNVKLEFDNKNLEGKNLALQRAKDSLLKERDNLRETVDELKCGHLSSNSGLTGTAVSRELQPPATVEKMQRLEAENKALREGQGGQTALAQLLDDANKRCENLREQLKSANERILSLSHASQSDDPILKESEFGKQIKQLMELNEQKTLQLEESVTQSSSLQCKVTQLETNLTAREQEVMAYDAKYRKCLEKAKEVIKSFDPRIASAIDASALEKYFDVVEEEPKPKMSVMEEQLMTSAFYRLGVNAQRDAVDSKLAILMGSGQTFLARQRQSAPRKSLSAMKSK", "output": "Involved in endocytic trafficking by stabilizing organelles of the endocytic pathway. Probably acts as a cytoskeletal linker protein required to tether endosome vesicles to the cytoskeleton. Involved in modulation of endocytosis at stages required for down-regulation of membrane proteins that control synapse size. Not involved in synaptic vesicle recycling. Required in R7 cells for boss endocytosis into multivesicular bodies (MVBs). Has a role in regulating adult longevity."}]}
+{"id": "function_test_2372", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MANIVFKLSDKDITTLMSRISFDTENLPQGMKARAKYQNTTVNIYQSGKVMFQGNHAEAVSEELLPQHSQLNTNKTKKKNMANSFLEQTLMYDQFNCIGSDEAGSGDYFGPLTVCAAFVTKEHVPILKTLGVDDSKKLTDTKIVELAEQLVTFIPHSLLTLHNEKYNIQQAKGWTQVKMKAALHNEAIKNVLEKIDSSQLDYIVIDQFAKREVYSHYALSDIPLPKKTKFETKGESKSLAIAVASIISRYAFVTYMDQISKNINMTIPKGAGAKVDVIAAKIIKKYGLSRLDTISKKHFKNREKAQKILKPL", "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."}]}
+{"id": "function_test_2373", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSVAVRVIPCLDVDAGRVVKGVNFTDLRDAGDPVEMARLYDAEGADELTFLDITASSGDRETTYDIVRRTAEQVFIPLTVGGGVRSVDDVNRLLRAGADKVGINTAAVARPELVRECAHRFGNQCIVISVDARRPPGPDGPRFEVTTHGGRKGTGIDAVAWTARVVELGAGEILLNSMDADGTRDGYDLEMICAVRAEVDVPVIASGGAGDLAHFAPAIDAGADAVLAASVFHFGQLRIGEVKTALRGAGVPVR", "output": "IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit."}]}
+{"id": "function_test_2374", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MFNFLKKIFNSSKKALRKARTIANKVQNLEAQIALLDDKDFATKTAELKKLFQEGKTLNQLLPEAYALAKEATKRVTGLTPYYVQILGAVILHQGNIAEMKTGEGKTLTAIMPAYLNALSGNAVHIVTVNEYLAKREFEGSIGDVFRFLGMTVGLNTKDKDQTQKQQAYLCDVLYTTNSELGFDYLRDNMEIEASNLVMKRPYSYAIVDEVDSILIDEARTPLIISQSVKETKNLYKEAQRFVRTLKNSHYLIELETKTIELTEEGITKAENFFQIDNLYNIEHASLLHHVKNALKAAFTMHKDKDYLVDYKDGQVLIIDQFTGRALPGRQFSDGLHQALEAKEGLLIKKETSIGATITYQNFFRLYQKLSGMTGTAKTEEDEFRDIYNMEVIEIPTNVPMIRIDEPDFIFVSLKEKYDALIEELTSRHKKGQPILIGTTTVEVSEIISKKLKKHSIKHEILNAKNHSKEAEIIAKAGLKNAVTIATNMAGRGTDIRLGEGVKELGGLSVLGTERHESRRIDNQLRGRAGRQGDPGYSRFFISSEDELAQRFGGTRIEKIISLLQKISDSETKTSSKMVTKFFTKIQKKVESSNFDYRKYLLKYDDILRIQREIIYNQRKEILVSDKVEQIVQDLMKKTLNKAIFTHFTNKPNKCQTQALITFLENKFFPKQTFDLEEVQELCNNPKTNSLDSFQQYSFQKVKDILQSQKDFFVKDPEKAQYFAKGLKWITLKIIDNYYQRHINDMSSLRQGIGFVSYGQQDSFIEYQKEGQVLFNNMITKIANDITATILKFSFADSFQTPPKQKVFFKNDSSDDESSKKRRTRKVRTSKKPWN", "output": "Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane."}]}
+{"id": "function_test_2375", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNEREYIGRGRRKLEHLRFFQEDSKGSNGLEDVHLVHQALPELNWSDIDLTCRWLGKTLAAPFIINALTGGPPETLAINAALARVARRTGIALAVGSQRAGLENKEWRESFTIVRRENANGLILANIGAGNSPADAGEAVAMIAADGLQVHLNAAQELIMPEGDRAFRGWLENIRGMVNTLGVPVIAKEVGFGLSRETALQLYQAGVRIMDVGGRGGTNFAAIEERRRGRSVAALAGWGLSTAVSILEIRELGLPVEVVATGGIRSALDAARALALGAKIVGAAGYFLKILLEQGEDALTEEILQWQEDLKRICLLTGCTTPAELATKPVVITGQTRAWLEGRQRH", "output": "Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)."}]}
+{"id": "function_test_2376", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDGFAGSLDDSVSAASTSDVQDRLSALELRVQQQEDEITVLKAALADVLRRLAISEDQVATVRKAVPSKGPATLREALSMSCITNGGAGTRKPSHASSVAKKDTLSSAAKSVKRSSTLEKSHNSWDASEESRNKLMRAASTSKLTSKVSKATDKHKDIVISPEGEYIKMFMRGRPITMFIPSDVENYDDVRTELPPEKLKLEWVFGYRGRDCRANVYLLPTGEIVYFIASVVVLFNYEERTQRHYLGHTDCVKCIAVHPDKIRIATGQIAGVDKDGRPLQPHVRVWDSVSLSTLQVIGLGTFERGVGCLAFSKADSGVHLSVIDDSNEHMLTVWDWQKKSKIAEIKTTNEVVLAVEFHPTDAGTIVTCGKSHIFFWTWSGNSLARKQGIFGKYEKPKFVQCLAFLANGDVLAGDSGGIMLIWSKTNVESTASKGAKVLGVYQISKQIKAHDGSVFTLCQMRNGMLLTGGGKDRKVIMWDHDLNPEREIEVPDQYGTIRAVAEGKGDQFLVGTSRNFILRGTFNDGFQVEVQGHTDELWGLATHPFKDLLLTCAQDKQVCLWNSVDHSLEWTRVLDEPGHCADFHPTGTVVAIGTHSGRWFVLDAETRDLVSIHTDGNEQLSVMRYSVDGALLAVGSHDNFIYLYNVSENGRKYSRYGKCTGHSSYITHLDWSPDNQYIMSNSGDYEILYWDIPSGCKLIRNRSECKDINWTTYTCVLGFQVFGVWPEGSDGTDINALVRSHNRKVIALADDFCKVHLFQYPCSKPKAPSHKYSAHSSHVTNVSFTHNDGHLISTGGKDMSIMQWRLIEKVSHSQNDNIAESSSAVNSPVVSEKVLQPDTPTTLPQAVNKATEVEQTPAESMAPPEDALELEAQQPQDLDDVQSGKSSPLPEEANGQEPSDEVIEEPANSQIVDAQDENQDDDDAPLS", "output": "Essential for the formation and stability of microtubules (MTs) (By similarity). Required for the organization of the mitotic spindle and for the proper attachment of kinetochores to MTs (By similarity). Promotes the recruitment of NUDC to the mitotic spindle for mitotic progression (By similarity)."}]}
+{"id": "function_test_2377", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVLVATLFSLFTVSLCRSIPRSSPSSSPYTQATDLKIHDPTVINANGAYYAYGVGEHIVIHQAPGLAGPWKQIGSVLDKDSIIPKGDRAKPWAPTTIEVKGTFYCYYSVSNAGCRDSAIGVATSQSPGPGGWTDHGAIVQSGTGQGSDEHPFNEVNAIDPAVLVTGDKGHLVFGSYWSGIWQVPLNEDFSSVGNTTGLNAHHLAKHPKTERVNSQDQNPDPLCRDSSGRRPVEGAYISYHAPYYYLWLSWGQCCDYDPNNLPPSGEEYSIRVGRSESPHGPFVDKQGKELTQGGGELIYGSNNDVYAPGGQGVITVETGDILYYHYSLYRYSTHSLYTFANLDFNQGCTLFIQ", "output": "Endo-1,5-alpha-L-arabinanase involved in degradation of pectin. Its preferred substrate is linear 1,5-alpha-L-arabinan (By similarity)."}]}
+{"id": "function_test_2378", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTRKFFGTDGIRGQANSFPMTPEIAMKVGMAVGYIFRRKGQASRAVVGKDTRRSGYMLEKALVAGFTAAGMDVFLLGPIPTPAVAMLCRSLRADIGVMISASHNPFYDNGIKLFGPDGFKLSDQIELQIEAMIEGDMTPFLASHGDVGRAKRVDGDIYRYIEFAKRTLPRNISLNGLRVVVDCANGAGYKVAPAALWELGAEVITINNEPNGININEDCGSTHPIGLMKKVHEVRADVGIALDGDADRVLLVDENGTVIDGDQLMAVIAESWAASNRLEGGGIVATVMSNLGLERFLADRNLTLARTKVGDRYVVEHMREHGFNVGGEQSGHIVLSDFATTGDGLISALQILAVAQEQNKPISDVCRKFQPVPQLLKNVRTTGGKPLENKRVKSAIDEAKERLGGQGRLVIRPSGTEPLIRVMAEGDDRGLVEKVVNDIIDVISSESSAAA", "output": "Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate."}]}
+{"id": "function_test_2379", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MHYLNISFSHKNSTLDVREKLSYKDDYATKGCLSKLNSGESINESILISTCNRMEVFCSCSDIASATKHIFEMLAARSGVSIDELEGRADIFDDSSAIHHLFSVASSLDSMVIGETQIAGQLKDAFRFSYDNGFCSQKLARAMHHAFKCAAKVRNATDISSKPVSIASVAVSKLKSVLDNVEGKKALVIGVGEMSEITAKHLLSSGADVYITNRTKHKAEKLASECGAKVLDMQDLHKAVNEFEILFTATSSSEPIITDEIIKPCDFDRYWFDMAVPRDINYHKGDRINLYVVDDLKNIVDQNMSFREDGARKAHGIIGRSTVEFFEWLNTLNIEPMIKEIYEKAFEAARIESQRVIKKGFIPKEYEDQIHKMSQQVLKRFLHQMSSKMRSVSEESKADMLTSAVQFLIEKDQRDIPDKYKCEHALNIIEGR", "output": "Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA)."}]}
+{"id": "function_test_2380", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTLKNKSIVVLLSGGLDSSTVTSIAKKSEAKIFGLSFDYGQRHKKELHSASTIAKHFDIQEFKIIKLDLSLWGGSSLTDTKKNIPTEGVQTNKIPNTYVPGRNTIFISVALSYAEAIDADFIGLGVNALDYSGYPDCRPDYIKKFQELADLANKRGRENNPIKLWTPLLDLNKEQIIQLAMDNHVPLDKTWSCYSGDAKPCGKCDSCRIRNTAYKKWLNNKNKK", "output": "Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))."}]}
+{"id": "function_test_2381", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTITPQNLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIGLNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNKDEFYLLVLIAALGGILLANANHLASLFLGIELISLPLFGLVGYAFRQKRSLEASIKYTILSAAASSFLLFGMALVYAQSGDLSFVALGKNLGDGMLNEPLLLAGFGMMIVGLGFKLSLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAIRVVLAIIAFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQTGEMSMEAVGVYLAGYLFSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILAAVMTVMMLSLAGIPMTLGFIGKFYVLAVGVQAHLWWLVGAVVVGSAIGLYYYLRVAVSLYLHAPEQPGRDAPSNWQYSAGGIVVLISALLVLVLGVWPQSLISIVRLAMPLM", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_2382", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNLLDSDDVRHMLNALTALGVSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGGNVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQHYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQLARISQAA", "output": "Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate."}]}
+{"id": "function_test_2383", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTLWINGDWVTGQGALRVKRNPVSGEVLWQGNDADAAQVEQACRAARAAYPRWARLSFGDRQVRVERFAGLLESNKAELTAIIARETGKPRWEAATEVTAMINKIAISIKAYHVRTGEQRSEMPDGAASLRHRPHGVLAVFGPYNFPGHLPNGHIVPALLAGNTIIFKPSELTPWSGEAVMRLWQQAGLPPGVLNLVQGGRETGQALSALEDLDGLLFTGSANTGYQLHRQLSGQPEKILALEMGGNNPLIIDEVADIDAAVHLTIQSAFVTAGQRCTCARRLLLKSGAQGDAFLARLVAVSQRLTPGNWDDEPQPFIGGLISEQAAQQVVTAWQQLEAMGGRTLLAPRLFQAETSLLTPGIIEMTGVAGVPDEEVFGPLLRVWRCDTFDEAIRMANNTRFGLSCGLVSSEREKFDQLLLEARAGIVNWKKPLTGAASTAPFGGIGASGNHRPSAWYAADYCAWPMASLESDSLTLLAMLNPGLDFSDEV", "output": "Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate."}]}
+{"id": "function_test_2384", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MELRNKKLTHDEFMTERQQVLKTWETGKNVENFEDGVKYQQAIPEHKRFSLALLKADKEGKTLSQPRAGVALMDEHIELLKTLQEECDLLPSTIDAYTRLNRYEEAAVGIKKSIEAGTSKLNGLPVVNHGVAACRRLTETLQKPLQIRHGTPDARLLAKISMASGFTSYEGGGISYNIPYAKRVTLEKSIRDWQYCDRLMGMYEEHGIRINREPFGPLTGTLIPPFISHSIAIIEGLLALEQSVKSITVGYGQVGSLTQDVAAIQSLRELAHEYFQSYGYTDYELSTVFHQWMGGFPEDESKAFAIISWGAAVAGMSGATKVITKSPHEAWGIPTAAANIQGLKASRQMLNMVNEQKFPPCPAVELEIELIKSEVRAVLNKVFELGNGDIARGTVLAFEAGVLEAGAVPLPKDILDLHHDYVAERARCEGRQPTFQMVVDDINAVSHSKLIGRP", "output": "Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate)."}]}
+{"id": "function_test_2385", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKNLEIILQSSKMIGSGLATSGLIGAGAGVGIVFGCLILAFSRNPNLQKELFSYALIGFALTEAIGLLALVMAFLILFI", "output": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element."}]}
+{"id": "function_test_2386", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAYPLQLGLQDATSPIMEELMNFHDHTLMIVFLISSLVLYIISLMLTTKLTHTSTMDAQEVETIWTILPAVILIMIALPSLRILYMMDEINNPVLTVKTMGHQWYWSYEYTDYEDLCFDSYMVPTNDLKPGELRLLEVDNRVVLPMELPIRMLISSEDVLHSWAVPSLGLKTDAIPGRLNQATVTSNRPGLFYGQCSEICGSNHSFMPIVLEMVPLKHFENWSASMI", "output": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix."}]}
+{"id": "function_test_2387", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPTINQLVRKGRQSETTKSKSPALQDCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTNGFEVISYIGGEGHNLQEHSVVLIRGGRVKDLPGVRYHMVRGSLDTQGVKDRKQARSKYGAKRAKAAK", "output": "With S4 and S5 plays an important role in translational accuracy.; "}]}
+{"id": "function_test_2388", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLPNQERKLRVLVVDDSSFMRMVIRSVLEKDPAIEVIAVAMDGVEGVEKALALRPDLITMDIEMPRLDGISALKEIMAKAPTRVLMVSTLTCEGAKATFDALDAGAIDYIPKNVTDSIDAQKAFKEELLRKVKGSGISILGRPLVSPSPRLVVPPRPVIIPRPAGQRYQYVGIGASTGGPVAVQEVLGRIPGNFPHGIVVAIHMPKAFTGPYAERLNTKCSLQVKEAKAGDIVQPGVVLVTPGGMHTALVRQGSTVAIRTIATAEYPQYIYIPSVDHMLTTFADACNGSLLGVILTGMGADGFKGMKHLKTKGGGTIVQDEATSTIYGMPRACIEGGVADTVLPLTQIGTEITKIAG", "output": "Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid."}]}
+{"id": "function_test_2389", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTGEKLLYIETFGCQMNVSDSEKVASLLRGEGYSQTPDSSEADLIIVNTCSVRAKAEHKVYSYLGRFRKLKRDRRLLLGVGGCVAQQEGERLLKRVPWLDLVFGTHNLHLLPEMVRAAEQGERRAAVDFIDNEARLDLFPQADEGGGVTRFVTVMQGCDNFCSYCIVPYVRGREISRRSVEIIGEIRSAVAGGVREVTLLGQNVNSYGLKTPGELSFAGLLREISAIDGLERIRFTTSHPKDISPELIACFAELPKLCGHIHLPAQAGSDSILARMNRGYTRQEYLEKVAALRAARPEILITGDIIVGFPGETEADFLQTLSLMEEVRYTDIFSFAYSPRPETAAASLGDRIMRKETTERLERVQGLQRDMTIERHAGFVGTCQAVLVEGMSKRGDQLYGRTDGNLIVNFAGNPSLAGSLVDVRITRGYPNSLLGELAVFQ", "output": "Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine."}]}
+{"id": "function_test_2390", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSDQISIIAPDDWHVHLRDGEMLNQVVAHTARRFQRAIVMPNLRPPVTTVAAAQAYRDRIQAACPADLEFTPLMTAYLTDSIAPAELETGFREGVFAAAKLYPANATTNSAAGVTDLLQIDPVLETMARIGMPLLIHGEVTDPEIDIFDREAAFIERHLEPLRERHPELKVVLEHITTEQAVQYVSSADRHLAATITPHHLHINRNAMFAGGLRSDFYCLPVAKRECHRQALRRAATSGDPSFFLGTDTAPHERSSKESACGCAGIFNAPFALESYAQVFDQEGALEHFEAFTSLNGPAFYKLPANTHRITLQRRDHLVPELVNGLVPFHAGEILSWAVANAPDQVQL", "output": "Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate."}]}
+{"id": "function_test_2391", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSDLKCPFSGHTGAVTASAHTGNRQWWPIQIDLGLLHQHHPASNPLGDTFDYPAAFAGLDLEALKADLAALMTDSQDWWPADWGHYGGLFIRMAWHSAGTYRGADGRGGAGHGNQRFAPLNSWPDNTNLDKARRLLWPLKRKYGNAISWADLIILSGNVALESMGFRTFGFAGGRTDIWQPEEDVFWGKETEWLSDERHTTEGALDQPLAAVEMGLVYVNPEGPHGHPDPVASGPDVRDTFARMGMTMEETVALVAGGHTFGKCHGAAPVSQLEAEPEGAELHQQGLGWHNRFESGKGEHTITSGIEGAWKPHPTRWDQGYFEMMFTYEWELTKSPAGAWQWVAKDVKPEHMIPDAHVPGRASAPIMTTADLSLRHDPLMEPVARRFHQDQDAFADAFARAWFKLTHRDLGPRALYLGADVPEEIQIWQDPVPALDHPLIGAVEIKALKQKLLATGCSVGALVATAWGAASTFRGSDRRGGANGGRIRFQPQNTWEVNDPEQLRSVLQTLETVQQQFNAEATGGQRVSMADLIVLAGSAAVEQAAAAGGHSVTVPFLPGRMDASADQTDTASFNLLKPIADGFRNWQRSGLPLRAEECLVDRAQQLGLSAPEMTVLLAGLRVLGANNGGNRQGVLTDRVGVLSNDFCVNLLDMSIRWSPTSEAMEGYIGRDAQGSERWTASRADLVFGSNSQLRAIVEVYAQDDGASRFVSDFVQAWVKVMNLDRFDVR", "output": "Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity."}]}
+{"id": "function_test_2392", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPVIHKIHARQILDSRGNPTVEVDVYTESSFGRAAVPSGASTGVHEAVELRDGDKGVYLGKGVLKAVENVNTVIDEALRGMLVTEQEEIDARLLELDGTPNKSKLGANALLGVSMACAKAGAEYSGLSLFRYIGGTMANTLPVPMMNVLNGGAHADNTVDFQEFMIMPIGFSTYSDALRCGAEIFHALKALLHSRGLSTAVGDEGGFAPNLRSNEEAIELVVEAIGKAGYKAGSPASKGGLGDAQVMIALDPASSEFYDTEKKKYVFKKSDKRELSSEEMASYWEGWANTYPIISIEDGMAEDDWAGWKLLTEKIGDRVQLVGDDLFVTNSLRLAEGIEKGVGNSILIKVNQIGTLTETLRAIDLAKRNGYTSVISHRSGETEDSTIAQIAVATNAGQIKTGSMSRSDRMSKYNELLRIEEELGEQAIYPGKQAFRV", "output": "Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis."}]}
+{"id": "function_test_2393", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPRFSDQLLYIGGRYVPARGGHTFEVVNPATGEVLANVHNAGADDLDAAVDSAQAGQRQWAALTTVERSRILLRAVALLRERNDALAELETLNTGKPLSETRSVDVVTGADVLEYYAGVAQALQGAQVPLREGSFFYTRHEPLGVVGAIGAWNYPIQIALWKAAPALAAGNAMIFKPSEVTPLTALKLAEIFTEAGLPDGVFNVLPGDGASVGTALTEHPQIEKISFTGGTATGRKVMASASSSSLKEVTMELGGKSPLIVCADADLDLAADIAMMANFYSSGQVCTNGTRVFVPRALRHAFEARLLARVQRIHIGDPLDERTTFGPLVSAAHMQRVLEHIEQGKAEGARLLCGGERLQDGALAQGYYVAPTIFSDCTDVMTIVREEIFGPVLSLLTYDDEDEAVTRANATTYGLAAGVVTPDLARAHRLIHRLEAGICWVNTWGESPAPMPVGGYKQSGVGRENGLATLQAYTRTKSVQIELERYASVF", "output": "Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the irreversible oxidation of betaine aldehyde to the corresponding acid."}]}
+{"id": "function_test_2394", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTNAVYLASASPRRKELLTQLGIEFTQFSVDADESQLPNELPYDYVERLARLKAQSGVALGYTDRPVLGSDTVVVIDNQSLGKPCDENDFTHTLKRLSGNTHQVLTAVAFATTDKVLSCVVSTNVTFKTLSDDEIHTYWQSGEPQDKAGGYGIQGLGGRFVTHISGSYFAVVGLPLYETEQLLQTFLRG", "output": "Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids."}]}
+{"id": "function_test_2395", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTAKRIDGKAFAAGVRARVAEEVARLKEGHGIVPGLAVVLVGEDPASQVYVGAKGKQTVEVGMASFEHRLPAGTSEAELLALIDRLNHDPAVHGILVQLPLPAHLNADLVINALDPAKDVDGFHISNVGRLGTGQKSMVPCTPLGCLMMLRDHLGALSGLNAVVVGRSNIVGKPMAQLLLGESCTVTIAHSRTRDLAAVCRGADILVAAVGRPEMITGDFVKPGATVIDVGINRIERDGKTKLVGDVDYASAAEVAGAITPVPGGVGPMTIACLLANTLTACCRANGLPEPQGLTA", "output": "Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate."}]}
+{"id": "function_test_2396", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAGFPGKEAGPPGGWRKCQEDESPENERHENFYAEIDDFAPSVLTPTGSDSGAGEEDDDGLYQVPTHWPPLMAPTGLSGERVPCRTQAAVTSNTGNSPGSRHTSCPFTLPRGAQPPAPAHQKPTAPTPKPRSRECGPSKTPDPFSWFRKTSCTEGGADSTSRSFMYQKGFEEGLAGLGLDDKSDCESEDESNFRRPSSHSALKQKNGGKGKPSGLFEHLAAHGREFSKLSKHAAQLKRLSGSVMNVLNLDDAQDTRQAKAQRKESTRVPIVIHLTNHVPVIKPACSLFLEGAPGVGKTTMLNHLKAVFGDLTIVVPEPMRYWTHVYENAIKAMHKNVTRARHGREDTSAEVLACQMKFTTPFRVLASRKRSLLVTESGARSVAPLDCWILHDRHLLSASVVFPLMLLRSQLLSYSDFIQVLATFTADPGDTIVWMKLNVEENMRRLKKRGRKHESGLDAGYLKSVNDAYHAVYCAWLLTQYFAPEDIVKVCAGLTTITTVCHQSHTPIIRSGVAEKLYKNSIYSVLKEVIQPYRADAVLLEVCLAFTRTLAYLQFVLVDLSEFQDDLPGCWTEIYMQALKNPAIRSQFFDWAGLSKVISDFERGNRD", "output": "Catalyzes the transfer of the gamma-phospho group of ATP to thymidine to generate dTMP in the salvage pathway of pyrimidine synthesis. The dTMP serves as a substrate for DNA polymerase during viral DNA replication. Allows the virus to be reactivated and to grow in non-proliferative cells lacking a high concentration of phosphorylated nucleic acid precursors."}]}
+{"id": "function_test_2397", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTIAQEPTALNFECETGNYHTFCPISCVAWLYQKIEDSFFLVIGTKTCGYFLQNAMGVMIFAEPRYAMAELEEGDISAQLNDYAELKRLCEQIKRDRNPSVIVWIGTCTTEIIKMDLEGLAPKLEGELGIPIVVARANGLDYAFTQGEDTVLAAMAHRCPDKAPVAEAEKNERNAVQKLLNFGKKKELVAQEESEYVDHPPLVLFGSLPDPVVTQLTLELKKQGIKVSGWLPAKRFTELPVLEEGYYVAGVNPFLSRTATTLMRRRKCKLIGAPFPIGPDGTRAWIEKICSVFGITPQGLDEREAQIWAGLEDYVKLIRGKSVFFMGDNLLEVSLARFLVRCGMTVQEVGIPYMDKRYQAAELAMLEKACQEMGVPSPKMVEKPDNYNQVQRIYDLKPDLVITGMAHANPLEARGINTKWSVEFTFAQIHGFTNARDILELVTRPLRRNNNLKDLGWDKLVREEAKI", "output": "Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (ChlN-ChlB) is the catalytic component of the complex."}]}
+{"id": "function_test_2398", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTTVLAIETSCDETAVAIVNNRQVCSSIIASQIPVHQQYGGVVPEVASRAHLETINDAIAQAMDQAQLGWDKIDGIAATCAPGLVGALLVGLTAAKTLAILHNKPFLGVHHLEGHIYATYLSEPTLDPPFLSLLVSGGHTSLIYVKECGRYESLGETRDDAAGEAFDKVARLLKLGYPGGPVIDKLAQTGNSQAFALPEGKVSLAGGGYHPYDGSFSGLKTAVLRLVQQLERDGDPLPIEDISASFQATVAKALTKRAIACALDYGLDTIAVGGGVAANSGLRQHLQAAATANNLRVLFPPLKFCTDNAAMIACAAADHLSRGHLSPITLGVESRLSLSQVMKLYQ", "output": "Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction."}]}
+{"id": "function_test_2399", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKLLKSHPFLSLANSYVIDSPQPSNLNYAWNFGSLLALCLGIQIVTGVTLAMHYTPNIDLAFISVEHIMRDVNYGWMIRYLHANTASFFFLFVYLHIGRGLYYGSYKSPRALPWSIGVIILILMMATAFLGYVLPWGQMSLWGATVITNLLSAIPWIGKDLVEFIWGGFSVDNATLNRFFSLHYLLPFILAALAVMHLLALHEHGSSNPLGITANADRLYMHPYYTFKDLVTIFLFFLVLALFLFYAPNKLGHPDNYIPANPMQTPASIVPEWYLLPFYAILRSIPDKLGGVIAMFGSLLILLAMPLLDLSRVRGSAFRPLMKFFFWLLVVDFLILLWCGSQHVEEPFITLGQFATTFYFSWFLIIVPVVSVIENTLIDLATENKS", "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."}]}
+{"id": "function_test_2400", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRIGNGYDVHRLAPGQKLVLGGVEIPFECGLIGWSDADVLTHAIMDSLLGAAALGDIGLYFPPGDPKYKGISSLKLLEQVTDLLAKKGFGIINVDSVIVAEEPKLRGHIDTMRKHLAKAMGIDPGRVGIKASTSEQLGFVGRQEGMVAWAVALVDEK", "output": "Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)."}]}
+{"id": "function_test_2401", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLKTHSCALTQENVGTEVTLAGWVHRRRDHGGVIFIDLRDREGIVQVIFNPEQSAACLDIGKELRSEYVLQVKGVVSHRPAGTENNRMPSGMVEVVAVNAKILNAAKTPPFYINEEVEVDESLRLKYRYLDIRRQGMKNNLIIRHKAVRFMREFLNDQGFIEIETPILIKSTPEGARDYLVPSRLFPGKFFALPQSPQQLKQLLMVAGMEKYYQVARCFRDEDLRADRQPEFTQLDMEMSFVDEEDMMKLMEDLFTGLVANVRPDMKYNKKFPRISFADAMEKYGCDKPDLRFGMELADITDIGASSAFGVFKNVAAQGGAIKAISAPGCGGYNKSQQEELINLAKKYGAAGLVPISLGVENGVLKDLTMEMVKSVAAKYLALEEIKTIAERSGAKPGDLILIVAGARKMVNTVLGEMRNQLAVKLNLCDKNELSFAFVVDFPLFQWDEEGKRWDSVHHPFTAPLESDMPLMDTDPGRVGSRAYDVVCNGYEIAGGSIRIHQADLQRKVFHLLGYNDEQIDERFGHLLEAFEFGAPPHGGVAPGIDRFVMLLAGETSIREVISFPKNQAAQDLLFGAPSVVDDKQIKDLHIRIQAEKE", "output": "Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn)."}]}
+{"id": "function_test_2402", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKKTPLLNIALSRVIASLGHGDILMIVDAGMPVPAGVELIDLALTRGVPDFVSVLDVVLSEMQVESHVLSNEMAEVKPPALQVIESLNLDDQLGQQRWISHEDLKVLSRKAKAIIRTGECQPYSNVALVSGVVF", "output": "Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose."}]}
+{"id": "function_test_2403", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKSYEVNFDGLVGPTHNYGGLSYGNVASQSNSQQGSNPREAALQGLAKMKALMEMGFQQGVLAPQERPDVAALRNLGFAGTDAQVIQQAAKQAMPLLVASCSASSMWVANAATVSPSADTADGRVHFTAANLNCKYHRSIEHPTTSRVLGAMFADQKHFAHHAALPAVAQFGDEGAANHTRFCRDYGQAGVEFFVFGRSAFDTRYPAPQKYPARQTLEASQAVARLHGLSEEGVVYAQQNPSVIDQGVFHNDVIAVGNGEVLFYHEDAFLETDKMLAELQGKLGKRGGNFQSICVPRSQVTVEDAVRSYLFNSQLLSRADGSMLLIVPEECRGNERVWQYLQSLTSSGGLIREVKVFDLKQSMQNGGGPACLRLRVALKETELAAVNPGVIMTAPLYDTLTQWVGKHYRDRLSESDLADPQLLLECRTALDELTQILKLGAVYPFQIN", "output": "Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2)."}]}
+{"id": "function_test_2404", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIEGLGDEVTVAVGLFILLLAITLAWLSTYVAEGSDPLLGSLIPTGRRDPLLVLSNPVPASPEPQRPAEAQAEKPEEGEQDPGGEQEAGSENANLDQMLDIQGVSKRSHAVPPLREEDGTEQDVTQEDDKEAESPLIVGRKIEQEEEKPLAKEGMTREKPEEALMTVRLKFLNETEEVAMVRPNDTIGMLKSKYFPGQEQQMKLIFQGQLLHDSSQTLCSLHITDNCVIHCHRSQATTPTSSSSPESGGSSQEHTGLTPPIGNLMIPVFVVMLALIWYFRINYRQFFTAPATVSLVGVTVFFSFLVFGMYGR", "output": "May contribute to the regulation of translation during cell-cycle progression. May contribute to the regulation of cell proliferation (By similarity). The membrane form is involved in sterol-regulated ubiquitination and degradation of HMG-CoA reductase HMGCR. May be involved in centrosome assembly."}]}
+{"id": "function_test_2405", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSEPVLMDRFARKVDYLRMSVTDRCDFRCVYCMAEEMTFLPRQQILSLEEILQVAERFVALGTRKIRLTGGEPLVRAGVVGLCEKIAALPGLRELCMTTNGSQLDKLAAPLFKAGVTRLNISLDSLDPQRFRELTRTGDLHKVIAGIDAANAAGFVHTKLNCVVMHGRNDDEINDLLAFAIDRNLDVSFIEEMPLGIISEHSRAESFYSSDQVRERIAERYTLVPSTDSTQGPSRYWRLAEAPGIRIGFISPHSHNFCGTCNRVRMTVEGRLLLCLGNEHSVDLKAVLRANPGQPEKLEKAIIDAMQLKPWSHNFTHDDGVQVVRFMNMTGG", "output": "Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate."}]}
+{"id": "function_test_2406", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTTFDHPSMIRQPKPTGLAGGLVLAALMLSSSLALADATPNQLGSEITAKLQDETSIAIAPASDSKRVYVLDPGNFHMTSTVYTIDGKSSKLLGMTDAGKLPNVMVASDGKFLAIANTMYSRVARGKRDDYLELIDTKTHQPIADIDIPEGRFLTGVFERTAGLSVDDKHLLFQQFSPSPGVGLVDLQQKAFVKIMNVPDCYHIFPTANQNFFMHCRDGSLMQFTYDSKGNTKQKPTKIFHAEKEYLLNNPYYSNSNNHLTWPTYEGKIFQAKLSESGAEFLKPIEVFTDKEKADKWRPGGWQTIAFHKARNELYLLADQREKWTHKLPSRFVFVVDATSGKRLRRIELKHEINSIAVSQDDKPYLYAVSEEAKTLFTFDAVNGKALSSIDELGRAPSMIFIADK", "output": "Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin."}]}
+{"id": "function_test_2407", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEQSQGNIANSPPTSEIPQRPIILSPPPLDQNSLNQSFNNLPTSVPQGHANRQQSVGYNLQHEFETLTANLDLDLNSSTRNITQSAPPNQQQQQQSQLQATDSQLLTTTADLNTKPAHSVKPTLAAPAASRYGSHLGSDLLGKSTSSLLGDNNPVSPIQKFSSINTQLDSLLNNNISSAKSKTGTNSPFLSNAGLSNRPQSVNDFSNIFNRQDQQQQQQSQTFSSFTTQQQSQNQNQNQNQSNFYSDLIVFSNWIENLNPQDNLTMIDYLCSNLPLDILLTFKSKLDLHLQGGSAQNQQSQQSQLLPQFVMSPYSQYDQQLYNDMDKLNIQDDSFKSKHGNSSFRSNHLANLIDKVERPKSADPFVNNTKYGQYQQQSYNQHSYQQQHPLVDRAKSPTSHLYEKTNFLQLAAANSNNTGGNYNQYMPSLSSTSSSLGQANSNNTSTRDDMDLKLGALATINSRVALDSNRKHPHVATPGSTWNNQTHTHSHISPPHHNQMHSGVRNVSNFEESINRSLNSSSVPASMHKSNYSNSHGNNSNNNSGNTNINSNQNKGTHKKKINSPTSAVSMQQNSTSVNSTTSGNGGANANVNTTATTSSSSSSSMPIEVSSLELLNNIPAWLKLLRLHKYTECLKDVPWKELIELDNDQLESKGVAALGARRKLLKAFDVVKNNLPVV", "output": "RNA-binding protein involved in post-transcriptional regulation through transcript degradation."}]}
+{"id": "function_test_2408", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MQLTNFTDFGLRALIYLGSLPEGELTSITVVTETFDVSRNHMVKIINKLGQEGYVKTIRGKNGGICLGKPADQIIIGDVIRAIEPLQVVNCAPEFCHITPACRLKGALAKAKQAFLDELDKHTIQDMLTDNSELLILLKRI", "output": "Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity."}]}
+{"id": "function_test_2409", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MATDPRKILVTCALPYANGSIHLGHMLEHIQADIWVRYQRLRGNDVNFICADDAHGTPIMLKAQQMGISPEEMIAAVSEEHQKDFAGFDISFDNYHSTHSDENRELASHIYLELKKNGFITSRTISQLFDPEKEMFLPDRFVKGTCPKCKAEDQYGDNCDNCGETYSPTDLINPKSAVSGATPVMKDSEHFFFDLPQFESMLKEWTRSGSLQSETANKMQEWFESGLQQWDISRDAPYFGFEIPGETNKFFYVWLDAPIGYMGSFKNLCNKRDDLNFDEYWKKDSTTELYHFIGKDIVYFHSLFWPAMLDGAGFRKPNNVFVHGYVTVNGAKMSKSKGTFIKAGTYLNHLDPECLRYYYAAKLNSRIDDLDLNLEDFTQRVNSDVVNKIVNLASRNAGFITKRFDGKLADNFVEPELYNEFIAAADRIAELYETREFGRAIREITALADKANQYIDEKAPWVLAKEEGKEQELQEVSSVGINLFRVLMAYLKPVMPELAARTEAFLNETLTWEGVAQPLVAHEITKFKALFARIDPKKVEAMIEESKEDAAIEMAAKEKAEAEKEKASQTELDKDPIADEIEFDAFEAVDMRIARIISCEEVPKANKLLKFQLDIGGETRQVFSGIKSAYKPEELEGKLTVMVANLKPRKMKFGMSEGMILAAGPGGKELWILEPHEGAQPGMRVM", "output": "Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation."}]}
+{"id": "function_test_2410", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MASIAVCPGSFDPVTYGHLDIIKRGAKVFDQVYVAVLNNSSKKPLFTVEERIELLREVTRTLPNVHVEAFHGLLVDYARSKKANAILRGLRAVSDFEYEMQITSMNRVLDENIETFFMMTNSQYAFLSSSIVKEVAKYNGDISELVPPVVEQALKRKFASTAAD", "output": "Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate."}]}
+{"id": "function_test_2411", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVDVNRFKSMQITLASPTKVRSWSYGEVKKPETINYRTLKPEREGLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVSHIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKETPLERKSLLTEREYREKLQEYGQGSFVAKMGAEAIQDLLKQVDLEAEIAELKEELKTATGQKRFKAVRRLDVLDAFYKSGNKPEWMVLNILPVLPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELGAPGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLGKRVDFSGRSVIAVGPTLKMYQCGVPRLMAIELFKPFVMREIVAREYAGNVKAAKRMVERGDERIWDILEDVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNADFDGDQMAIHVPLSEEAQAEARLLLLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDEGREGEGMIFKDIDEAVMAYHNGYVHLHSRVGIAVDSMPDKPWKENQLHKILVTTVGKILFNSIIPSEIPYLQETTNENLTDSTPDKYFLEPGQDIQTVIDSLEINAPFKKKHLGNIIAEIFKRLRTTETSAFLDRLKDLGYYYSTLAGLTVGIADIPVIDNKQEIIDAAHHRVEEINKAFRRGLMTEDDRYVAVTTTWREAKDALEKRLIETQDPKNPIVMMMDSGARGNISNFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSGYLTRRLVDVAQDVIIREDDCGTDRGLVIRAITDGKEVTETLEERLFGRYTKKSVKHPETGEVIVGPDTLITEDMAAAIVNAGVEEVTIRSVFTCKTRHGVCRHCYGINLATGDAVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAVITEVKGTVIEIEEDAATRTKKVFVQGKTGMGEYVVPFTARMKVEVGDEVHRGEALTEGSIQPKRLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGDTDLLPGTLMDISDFTDANKDIVISGGVPATSRPVLLGITKASLETNSFLSAASFQETTRVLTDAAIRGKKDHLIGLKENVIIGKIIPAGTGMARYRNIEPLAVNEVEVIENIAVDEAIVESSED", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_2412", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MMFEKTLSILKPDVVERGIIGRVLSYIEAAGLRIVAQRMCALSHEQAEAFYAVHKARPFFPSLVGFMTSGPVVVQVLVGESAVKTYRDVMGATNPSEAAPGTIRGDLAESIDANCVHGSDSLENAEWEIKFFFKEHEIMSSMPNGK", "output": "Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate."}]}
+{"id": "function_test_2413", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKLLKEEGFSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAETAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDRVIPYWTDTILPRMKSGERVIIAAHGNSLRALVKYLDNMSEDEILELNIPTGVPLVYEFDENFKPLKHYYLGNADEIAAKAAAVANQGKAK", "output": "Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate."}]}
+{"id": "function_test_2414", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKSGRFIGVMSGTSLDGVDVVLAAIDETMVAQQASLTWPIPVHLKKGILDICQGQPLTLSQLGQLDTQLGRLFAQAVNALLAQQRLQPRDIVAIGCHGQTVWHEPTGEAPHTLQIGDNNHIVAHTGITVVGDFRRRDIALGGQGAPLVPAFHHALLGHPTEKRMVLNIGGIANLSLLFPGQAVRGYDTGPGNMLMDAWIWRQCAQPYDKDAAWAKEGQVILPLLQKMLRDPYFAASAPKSTGREYFNYGWLERHLAAFPGADARDVQATLAELTAVSIAQQVLLNGGCERLMVCGGGGRNPLVMARLAALLTGIEVSTTDKAGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGATEASVLGAIYPANPITQS", "output": "Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling."}]}
+{"id": "function_test_2415", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAEISRIQYEMEYTEGISQRMRVPEKLKVAPPNADLEQGFQEGVPNASVIMQVPERIVVAGNNEDVSFSRPADLDLIQSTPFKSLALKTPPRVLTLSERPLDFLDLERPPTTPQNEEIRAVGRVKRERSMSENAVRQNGQLVRNDSLYGISNIDTTTEGTSDDLTVVDAASLRRQIIKLNRRLQLLEEENKERAKREMVMYSITVAFWLLNSWLWFRR", "output": "Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles."}]}
+{"id": "function_test_2416", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNSSNIRRIQNEYNKINNDKNLYADSFQINMVDENIFLWKVNIKGPENSLYENYNFELEIELSNDYPYSSPKVKFITPIQHMNVNDKGDICLNILKKDGWNASLNIISIIWSIIVLLDQPNPEDPFNSELASLYRNDKLSYDKKIRDYCKTHSKLWTF", "output": "Catalyzes the covalent attachment of ubiquitin to other proteins."}]}
+{"id": "function_test_2417", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRFGVDEAGKGPVLGSMFAAAVRADPAALPGGVGDSKDIRPERRERLAKEIRESADAVGIAEISVERIDADETDMNTLTVEGQAEALSAVARDGLSGTVDAGDTDAARFGRRVADAVDTDVAVTAEHGADETDSLVGAASIIAKVARDTHVAELAAEYGDVGSGYPSDPTTRTFLADYVDRHGELPACARRSWSTCDDVLAAASQSTLSDF", "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."}]}
+{"id": "function_test_2418", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTFLPQEFIRKVRDRAPLDTADVARFVQGVTAGDVTEGQIAAFAMAVYFNELPLSARIALTLAQRDSGDVLDWRGARLNGPVVDKHSTGGVGDLTSLVIGPMVAACGGYVPMISGRGLGHTGGTLDKLEAIPGYDVAPSVDMLRRVVRDAGLAIVGQTAQLAPADKRIYAVRDVTATVESISLITASILSKKLAAGVGALAMDVKVGSGAFMPSAEQSAELARSIVDVGNGAGMRTAATLTDMNQALAPCAGNAIEVRCAIDFLTGAARPARLEAVSFALAAQMLTMGGLAADAHDARRRLRAVLESGAAAERFARMVAALGGPADLVERPERHLPRAAAAAPVAAARAGWIERIDARALGLAVVGLGGGRAKIGDTLDYSVGLSALAELGERVEAGQPLATVHARDADSAAQATDAVRRAYRIGAEPPAQTRVVHAVIE", "output": "The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis."}]}
+{"id": "function_test_2419", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDMENLTWLHGKPTASGILKANPEDFVVVEDLGFEPDGEGEHLLVRIRKNGCNTQFVADYLARFAKLHPRLVSYAGLKDRHAVTEQWFCLHLPGKEAPDLATFELEGCEVLEAVRHKRKLRIGSLKGNAFTLVLRHITDRQDVEQRLQQIAAQGVPNYFGSQRFGRGGNNLVQARLWANNEIRVKERSKRSFYLSASRSAMFNLISSHRLAQQLSTTVLEGDALQLSGRGSWFVAQADELATLQQRVTAGELNITAPLPGDSELGTHGEALAFEQACLAEQTELLSLIKRERVEGSRRAVLLKPQNMISNWWDDVTLELSFWLPAGSFATSVVREIMNQDRADDTDIIE", "output": "Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs."}]}
+{"id": "function_test_2420", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNLIPMVVEQTPRGERSYDIYSRLLKERIIFLGSGVNDDVANVIVAQLLFLEAEDPEKDITFYINSPGGSVTAGMAIYDTMQYIKCDIATLCMGQAASMGAVLLAAGTAGKRYALPNSRIMIHQPLGGFQGQATDIEIHTKEILRIRKDLNNILAHHTGKTLKKIESDTERDNFMSSVEAQKYGLIDEVLVKREDVEGAADNG", "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins."}]}
+{"id": "function_test_2421", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSENVKKNWIKTIMESMGSLKRTHFCDALRKEDIGKQVILMGWVLRRRDHGGVIFIDLRDRRGITQVVFNPEINPEVHAKAHSLRSEWVLAIKGTVSARPGDMANTKLGTGDIEILVDELVILNTSETPPFPLDEETEVSENLRLQYRYLDLRRPAMARNLLLRHKAVQAIRNYLNDNEFLDIETPMLTRSTPEGARDYLVPSRVSAGKFYALPQSPQLFKQLLMIAGMDRYYQIVKCFRDEDLRADRQPEFTQIDMELSFVDEEQIIEVTEGMIQTLFKETLDLDLTPPFAHITYADSMERFGCDRPDMRFGMELVNLTEIAKSCSFKVFRAIAEEGGTVRAINAKACAHFSRKDLDGLTEYAALFGAKGLAWVKMKADGEWQSPIAKFFSEEERASIAEALDAQEGDLLFFGADSEKVVFQVLGELRLEMARRLDLLDKKEFNFVWVTDFPLMEYDEKEDRYQSIHHPFTAPREEDLDLLETAPDKALSRAYDLVLNGTEIGGGSIRIHQRDVQARVLTALGIDKEEADEKFGFLLRALELGAPPHGGLAFGLDRLMMLITGSDSIRNVIAFPKTQKAACLLTEAPATVARKQLTELYLRPDWKE", "output": "Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn)."}]}
+{"id": "function_test_2422", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQIFYDKDCDLSIIQGKKVAIIGYGSQGHAHALNLKDSGVDVTVGLRANSASWKKAENAGLKVAEVPEAVKQADLVMILTPDEFQSQLYRDVIEPNIKEGATLAFAHGFSVLYNQVVPRQDLDVIMVAPKAPGHTVRSEFQRGSGVPDLIAIHQDASGNARNVALSYASGVGGGRTGIIETSFREETETDLFGEQAVLCGGAVELVKMGFETLVEAGYSPEMAYFECLHELKLIVDLMFEGGIADMNYSVSNNAEYGEYVTGVEVINEQSREAMRNALKRIQSGEYAKMFIQEGALNYPSMTARRRQNAAHGIEVTGSKLRAMMPWIQANKIVDKEKN", "output": "Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate."}]}
+{"id": "function_test_2423", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSNKNKSYDYVIIGGGSAGSVLGNRLSEDKDKEVLVLEAGRSDYFWDLFIQMPAALMFPSGNKFYDWIYSTDEEPHMGGRKVAHARGKVLGGSSSINGMIYQRGNPMDYEGWAEPEGMETWDFAHCLPYFKKLEKTYGAAPYDKFRGHDGPIKLKRGPATNPLFQSFFDAGVEAGYHKTPDVNGFRQEGFGPFDSQVHRGRRMSASRAYLHPAMKRKNLTVETRAFVTEIHYEGRRATGVTYKKNGKLHTIDANEVILSGGAFNTPQLLQLSGIGDSEFLKSKGIEPRVHLPGVGENFEDHLEVYIQHKCKEPVSLQPSLDIKRMPFIGLQWIFTRTGAAASNHFEGGGFVRSNNEVDYPNLMFHFLPIAVRYDGQKAAVAHGYQVHVGPMYSNSRGSLKIKSKDPFEKPSIRFNYLSTEEDKKEWVEAIRVARNILSQKAMDPFNGGEISPGPEVQTDEEILDWVRRDGETALHPSCSAKMGPASDPMAVVDPLTMKVHGMENLRVVDASAMPRTTNGNIHAPVLMLAEKAADIIRGRKPLEPQYIDYYKHGVHDENEGAIEVKPYAK", "output": "Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate."}]}
+{"id": "function_test_2424", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRIIKYLTILVISVVILTSCQSSSSQESTKSGEFRIVPTTVALTMTLDKLDLPIVGKPTSYKTLPNRYKDVPEIGQPMEPNVEAVKKLKPTHVLSVSTIKDEMQPFYKQLNMKGYFYDFDSLKGMQKSITQLGDQFNRKAQAKELNDHLNSVKQKIENKAAKQKKHPKVLILMGVPGSYLVATDKSYIGDLVKIAGGENVIKVKDRQYISSNTENLLNINPDIILRLPHGMSEEVKKMFQKEFKQNDIWKHFKAVKNNHVYDLEEVPFGITANVDADKAMTQLYDLFYKDKK", "output": "Involved in heme (porphyrin) scavenging. Binds Fe(2+) and Fe(3+) heme but the largest fraction is Fe(2+) heme. Functions as a high-affinity heme binding protein and probably has a role in relaying heme-iron from cell wall-anchored isd proteins receptors to the probable permease IsdF (By similarity)."}]}
+{"id": "function_test_2425", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKRHTRKIAIIGTGLVGSSCAYSIVNQGICEELLLIDINHERAVGEAMDLSHCINFTNTRTKVYAGSYEDCKDMDIVIITAGPAPKPGQSRLDTLGASAKIMESVVGGVMESGFDGIFLLASNPVDIITYQVWKLSGLPRNRVIGTGTSLDSSRLRTILSEMLHVDPRSIHGYSLGEHGDSQMVAWSHVTVGGKPILQILEEQKERFGEIDLDEIVEKTAKAGWEIYKRKGTTYYGIGNSLAYIANSIFNDDHRVIAVSAILDGEYGEYDICTGVPAIITRDGIREIVELNLTEDEESRFAKSNDILRDYMKTIGY", "output": "Catalyzes the conversion of lactate to pyruvate."}]}
+{"id": "function_test_2426", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSTVNVQIGLHELLNGSNAQIQLSVPQLVEKVLMRNEGKLTSTGAVSASTGKYTGRSPKDKFIVKEASVADKIAWGAVNQPISEEHFNKLYTKVLEYLKEKEELFVFKGFAGADRNYRLPIQVINEYAWHNLFVHQLFIRPTEEELTTHESEFTIVSAPNFKADPAVDGTNSEAFIMVSFEKRIVLIGGTEYAGEMKKSIFSIMNFLLPEQDILSMHCSANVGEEGDVALFFGLSGTGKTTLSADPNRKLIGDDEHGWSDNGVFNIEGGCYAKCVNLSHEKEPQIFDAITFGSVLENVIINDQTRIADYNDTTLTENTRAAYPMHAIDNIVLPSVAGHPNTIIFLTADASGVLPPISKLSKEQAMYHFLSGYTSKLAGTERGVTSPQATFSTCFGSPFLPLDASRYAEMLGEKIEKHDAKVFLVNTGWTGGEYGVGKRMNLGYTRAMIQAALSGELAKTETAKHDIFGLEVPLHVPGVPDEVLMPEQTWADKAAYKAKAIELANEFKANFKKFDSVSEDIINLGGPIA", "output": "Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA."}]}
+{"id": "function_test_2427", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQQSKEERVHDVFEKISDKYDVMNSVISFQRHKAWRKETMRIMDVKPGSKALDVCCGTADWTIALAGAVGEQGKVVGLDFSENMLSVGKQKVEALQLKQVELLHGNAMELPFEDNTFDYVTIGFGLRNVPDYMHVLKEMTRVVKPGGKVICLETSQPTMIGFRQGYILYFKYIMPLFGKLFAKSYKEYSWLQESASTFPGMKELANMFEKAGLERVQVKPFTFGVAAMHLGMKPESK", "output": "Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)."}]}
+{"id": "function_test_2428", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEANAPKRKEARKSLRIKVISMGNAEVGKSCIIKRYCEKRFVPKYLATIGIDYGVTKVQVRDREIKVNIFDMAGHPFFYEVRNEFYKDTQGVILVYDVGQKESFDALDAWLAEMKQELGPHGNMDNIVFVVCANKIDCTKHRSVDESEGRLWAESRGFLYFETSAQTGEGINEMFQTFYSAIIDLCDNGGKRPPSSMGVGFTKEQADAIRRIRNSKDSWDMLGVKPGATRDEVNKAYRKLAVLLHPDKCVAPGSEDAFKAVVNARTALLKNIK", "output": "GTPase possibly involved in regulation of the MEK/ERK pathway."}]}
+{"id": "function_test_2429", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRIFKSHPLLRLVNSYVIDSPTPSNLSYLWNFGSLLALCLIIQIVTGVTLAMHYTPSVAEAFNSVEHIMRDVNNGWLIRYLHANTASAFFFLVYLHVGRGIYYGSYKAPRTLTWIIGSIILIVMMATAFLGYVLPYGQMSLWGATVITNLMSAIPWIGQDIVEFLWGGFSVNNATLNRFFALHFVLPFVLAALVIMHLISYHETVGSGNPLGISSNYDRLPFAPYYIFKDLITIFLFFFVLSLFVFFMPNALGDSENYVMANPMQTPPAIVPEWYLLPFYAILRSIPNKLLGVIAMFSAILIILVMPITDLSKYRGLQFRPLSKVAFYVFVANFLILMQLGAKHVESPFIEFGQISTVLYFSHFLVIMPLVSFIENTLVELITKKS", "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."}]}
+{"id": "function_test_2430", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQRLEALGIHPKKRVFWNTVSPVLVEHTLLRGEGLLAHHGPLVVDTTPYTGRSPKDKFVVREPEVEGEIWWGEVNQPFAPEAFEALYQRVVQYLSERDLYVQDLYAGADRRYRLAVRVVTESPWHALFARNMFILPRRFGNDDEVEAFVPGFTVVHAPYFQADPERDGTRSEVFVGISFQRRLVLIVGTKYAGEIKKSIFTVMNYLMPKRGVFPMHASANVGKEGDVAVFFGLSGTGKTTLSTDPDRPLIGDDEHGWSEDGVFNFEGGCYAKVIRLSPEHEPLIYKASNQFEAILENVVVNPESRRVQWDDDSKTENTRSSYPIAHLKNVVESGVAGHPRAIFFLSADAYGVLPPIARLSPEEAMYYFLSGYTARVAGTERGVTEPRATFSACFGAPFLPMHPGVYARMLGEKIRKHAPRVYLVNTGWTGGPYGVGYRFPLPVTRALLKAALSGALENVPYRRDPVFGFEVPLEAPGVPQELLNPRETWADKEAYDQQARKLARLFQENFQKYASGVAKEVAEAGPRTE", "output": "Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA."}]}
+{"id": "function_test_2431", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDRLESVLKEERVFYPSEEFRKQAHIKSEEEYQRLYEESVRDPEGFWGRVASELHWFEPWRKVLEGDLPHPKWFVGGKTNLSYNALDRHVKTWRRNKAAIVWEGEPGEERVLTYHDLWREVQRFANVLKRLGVKKGDRVTIYLPMIPEAAIAMLACTRIGAVHSVVFGGFSAGALADRIKDAEAKVLITADGGFRRGGIVPLKQNADEALKDATSVEHVVVVRRTGEEVPWTPGRDHWWHELMEAAPDRCDPESMEAEEPLFILYTSGSTGKPKGVLHTTGGYMTYVYYTTKLVFDLKDEDVYWCTADVGWITGHSYVVYGPLLNGATTVMYEGAPNWPEPDRFWRIVDKYGVTVFYTAPTAIRSFMKWGEGWPGKHRLDSLRLLGTVGEPINPEAWLWYYHVIGKGRCPIVDTWWQTETGGIMITTLPGAHAMKPGHAGKPFFGVVPEILDGEHRPVENPDEGGHLCITRPWPSMLRTVWGDPERFLQQYFSQHPGVYFSGDGAKRDKDGYYMILGRVDDVLNVAGHRLGTMEIESALVAHPAVAEAAVVGRPDPVKGEAIVAFVTLKEGHTPSDALKEELRAHVAKVIGPIARPDEIRFTDALPKTRSGKIMRRLLRQIAAGEKEIKGDTSTLEDRSVVERLKEGA", "output": "Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA."}]}
+{"id": "function_test_2432", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDTLHHRFQQFQKTIWFNIFCYLWTGIFSFLAFAPVSLTHFVWIAPFGFFWLSLKYHGKYKKLFFHGLLIGVVFYAISFHWIIHMAITFGNFPYVVAILILLFAGLLFGLKFPIFMMSFSFLSGKIGRHSVWVAGFCGLLSELIGPQLFPWYWGNLAAGNIILAQNAEITGVYGISFLVFIVSYTLFQSNPWHWKEIIHSKEKRKQYLRFITLPALLLLTFIVSGIFLFKKWENVKPVKSLNVLIVQPDAPLSFRDGREIKESIEALMARIEKLTDEGAVRLGKKPDLIVLPEAGVPFFSAHKTEITTKVRRMYWDRFDSLMFLLANRYKANVFFNEIDAGFKGAPSPRNLRYYNNNVLYDPNGDRRDSYQKKFLLMFGEYMPFDFLYELSQQTGRFEPGLTHNLIRYYTPRYYTLAEKEKSPKGRHLGWTDTETFNHEAVRSYYETTRTEVSETGKFLPLICYEVILPEFVREFRTAGNPEFIVNLTNDKWYGATTESDQHMELGRLRSIELRRWMVRSTNSGISANIDHLGRFVGNKKTGLMTAEALSETIDVIDSPPTFYTQYGNLIPWLMLFLTGIYYLNLLIGIRRGKSS", "output": "Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation."}]}
+{"id": "function_test_2433", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTVPATDSCPAPIRVPAGTTAAAAVRDAGLPGRGAPDAVVVVRDASGTLRDLSWVPDTDAEVVPVAANTDEGRSVIRHSAAHVLAQAVQELFPQAKLGIGPPITDGFYYDFDVPEPFTPEDLDKLEKRMRQIVKEGQLFSRRVYESKEQARAELAGEPYKLELVDDKSGDPDIMEVGGDELTAYDNLNPRTRERVWGDLCRGPHIPTTRHIPAFKLTRSSAAYWRGDQNNASLQRIYGTAWESQEALDDHLRLIEEAQRRDHRKLGSELDLFSFPDEIGSGLAVFHPRGGVVRRELEEYSRRKHIEAGYEFVNTPHITKAQLFHTSGHLDWYADGMFPPMHLDAEYDDDGTVRKPGQDYYLKPMNCPMHTLIYRSRGRSYRELPLRLFEFGTVYRYEKSGVVHGLTRARGFTMDDSHIFCTREQLHGELASLLRFVLELLGDYGLTDFYLELSTKDPDKFVGSDEVWEQATTSLADVAAESGLELVPDPGGAAFYGPKISVQARDALGRSWQMSTIQVDFNFPERFELEYTASDGTRQRPVMIHRALFGSIERFFGILTEHYAGAFPAWLAPVQAVGIPVADEHVPYLESVAAQLKSYGVRVEVDASDDRMAKKIVHHTAQKVPFMLLAGDRDVAAGAVSFRFGDRTQINGVPRDSAVDAIVKWIADRENSVPSAELVKVSSGE", "output": "Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr)."}]}
+{"id": "function_test_2434", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSFPYFISPEQAMRERSELARKGIARGKSVVALVYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKPPELYRITYDGSIADEPHFVVMGGTTEPITTALKDSYAENANLREATRIAVRALRAGSESSNGDQSALDVGSLEVAILDVNRPRRAFRRINRPTLENLLRELDSNGSDGNGDAPELNGGSSD", "output": "Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation."}]}
+{"id": "function_test_2435", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIKSTLIFRDDGLPLCSSVDDDTDPSLADQKKKVKVLISRFTPQSANEATLESGAYEMHYVRQQSVVYIVIVERGYPRNLAFAYLADVRHEFEHSYGNEYVKPSVRPYAFVSFDNFLQKTKKIYNDKRVQGNLDQLNSDLLGVKQIMTKNIEDLLYRGDSLDRMSDLSASLRQDSKKYRRSAQKINFDLLLSQYAPVALIGLFFLFLVWWLVFR", "output": "Required for transport from the ER to the Golgi complex."}]}
+{"id": "function_test_2436", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MCSVLRFQRNMASWVKRHVFTFDLGDIQEKRGSDSGSGQSRSTADRYFNAVFGLGLLLFCIVCMAYLSPFLGSDLPQCRSVTMYPSYALVQGFDRRFSRLGRKYHLYLYREAGKDNGFSDDNEIHLDGIPVLFIPGNAGTYKQVRSIAAATANLYYGEMRDALNNNNTKNLDFFTADFNEDFTAFHGRTMLDQAEYCNDAIRYILSIYELSDKYRASGEPLPTSVLVVGHSMGGIVARVMTTLKNHIPQSINTILTLSSPHSTAPATFDGDILKIYNAMNAFWESKFRDRDKDPFYAENVSVISITGGVLDSVLPADYTSLEGIIPSDNGFTTYTTTIPWVWTPIDHLAIVWCDQLRIVVAKLLLELVDRTSASKTRPLPDRMRLARRSLLSGLESSASADFHLWDNEDYIFQPKVAPGALTTAQEMSPILLNVETYDTLNEYNYLAIPHNEPNLRFSLLTSLENLEELHILFCQNYNEHNSNGPIEYSSRCVSPSQDFIHVPRSFENSKYPSESSVGSASLPFKALHFNQTLLSKYDFIKFRKPSKSSFKDEDFVLVELSTTDWQTTVNCNPFQLLLSSAKFAHNASSAPFIQTFRFPYLSSSLVSYKLDVSYTGENLVFEPFIAQSIDSPFETKWHLRLRDSVTITIHSEAPFIPFESHYDKSVKLRLIAPPDCNINLSLSINWYMTLKFLFIRYRLAVAALPLSLVSFVLANQFALYYSSSFFPDFSTTLRAVTSKFWLKLTLSSILLTPILNISFIQRLIHSLDPSGVNSPFLIRKKNIMTAAYYLGIREIFMCWIGPLLSCITLSLVYMLAFGISTLESCVRRVSCYMSTAISKTRMKEIWLKDECEYEEGLVLRRRIGSGIMILAVVLYVPYQLVFVLLFLVQLNTVIKLNINYFNTKRHSNLRNYNSSYLLLMLCVLPINAPMVFVFLHNFGRRWVTSFRSHHNCLAILPIILLVCDNAGLRIPRSHCIERISKLITIGSFLYLSLYSVIYGIRNLFWAHHLVNLISGWLLFTSLDLTSNN", "output": "Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins."}]}
+{"id": "function_test_2437", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRMIDIIEKKRDGHTLTTEEINFFIDGYVKGDIPDYQASSLAMAIYFQDMNDDERAALTMAMVNSGDMIDLSDIKGVKVDKHSTGGVGDTTTLVLAPLVAAVDVPVAKMSGRGLGHTGGTIDKLEAIDGFHVEIDEATFVKLVNENKVAVVGQSGNLTPADKKLYALRDVTGTVNSIPLIASSIMSKKIAAGADAIVLDVKTGSGAFMKTLEDAEALAHAMVRIGNNVGRNTMAIISDMNQPLGRAIGNALELQEAIDTLKGQGPKDLTELVLTLGSQMVVLANKAETLEEARALLIEAINSGAALEKFKTFIKNQGGDETVIDHPERLPQAQYQIEYKAKKSGYVTELVSNDIGVASMMLGAGRLTKEDDIDLAVGIVLNKKIGDKVEEGESLLTIHSNRQDVDDVVKKLDSSITIADHVVSPTLIHKIITE", "output": "Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate."}]}
+{"id": "function_test_2438", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "GVSGSCNIDVVCPEGNGHRDVIRSVAAYSKQGTMWCTGSLVNNSANDKKMYFLTANHCGMTTAAIASSMVVYWNYQNSTCRAPGSSSSGANGDGSLAQSQTGAVVRATNAASDFTLLELNTAANPAYNLFWAGWDRRDQNFAGATAIHHPNVAEKRISHSTVATEISGYNGATGTSHLHVFWQASGGVTEPGSSGSPIYSPEKRVLGQLHGGPSSCSATGADRSDYYGRVFTSWTGGGTSATRLSDWLDAAGTGAQFIDGLDSTGTPPV", "output": "Highly specific endopeptidase that hydrolyzes lysyl bonds including the Lys-Pro bond."}]}
+{"id": "function_test_2439", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKKAVILLNMGGPSSLLEVDMFLKNMFNDPRILPIKSPFFRSLVASFIANRRSETAKANYRKIGGKSPLIGHTFNLIQKLQSLDPSRFYTYAMRYTPPMTDMAVRELAQKEIEEVTLFSLYPQYSTTTTLSSIEEFHKQCALLSYFPKTKEIDRYFEDSNYNEAIIDRILEALGGDNPEEFTLIFSAHGLPQSVIDAGDPYEKEVHANIQALTKLLEERGITFKKITHAYQSKVGPMKWLEPSLDEVLKLHAKEKILLYPIAFTLDNSETDFELRIEYQEKATHLGITDYRVASCLNDSTRFAHAIIKLISQGEIS", "output": "Catalyzes the ferrous insertion into protoporphyrin IX."}]}
+{"id": "function_test_2440", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEFSVKSGSPEKQRSACIVVGVFEPRRLSPVAEQLDKISDGYISSLLRRGDLEGKPGQMLLLHQVPGVLSERVLLVGCGKERELGERQYKEIIQKTINTLNETGSMEAVCFLTELHVKGRDTYWKVRQAVEATKDGLYTFDQFKSVKPETRRPLRKLVFNVPTRRELNLGEKAITHGLAIASGVKACKDLGNMPPNIANPAYLASQARRLADDYETITTKIIGEQEMEKLGMSSYLAVGRGSKNESMMSIIEYKGHPDSEAKPIVLVGKGLTFDSGGISLKPGEGMDEMKYDMCGAASVFGTMKALAKLNLPVNVIGVLAGCENMPGSNAYRPGDILTTMSGQTVEVLNTDAEGRLVLCDALTYVERFEPDCVVDVATLTGACVIALGHHITGVLSNHNPLAHELVNASEQSSDRAWRLPMADEYHEQLKSPFADMANIGGRPGGTITAACFLSKFAKKYNWAHLDIAGTAWKSGAAKGSTGRPVSMLVQFLLNRSGQETEE", "output": "Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides."}]}
+{"id": "function_test_2441", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTTNQQSVAASQPKTIVVKLGTSVLTGGTLALDRAHMVELARQCAELKKQGHSVVVVSSGAIAAGREHLGYPALPNAMASKQLLAAVGQSQLIQTWESLFALYGIKIGQMLLTRADLEDRERFLNARDTINALVDNGIIPVVNENDAVATSEIKVGDNDNLSALVGILCGADKLLLLTDQKGLYTADPRKDPNAELIKEVKVIDDTLRKIAGGSGTTLGTGGMATKLQAADIARRAGIEVIIAAGRGQNVIFDALSPAPQGTRFLPCEEALENRKRWILAGPAASGDIVIDQGAVKAVVEKGSSLLAKGVTKVLGEFSRGEVVRVTDAQGHLVARGIASYSNQDMAKIAGKHSKDIISILGYDYGSEVIHRDDMVVIQE", "output": "Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate."}]}
+{"id": "function_test_2442", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGKVVGIDLGTTNSVVAVLEGGQPTVIANAEGSRTTPSVVAFTKNHDRLVGQLARRQAVLNPENTFYSVKRFIGRKYDEITDEAKQVAYRVVRDGSNVKLHSTNEDKDFAPEEISALVLRKLVDDASKYLGEKITQAVITVPAYFNDSQRQATKDAGRIAGIEVLRIINEPTAAALAYGLDKKANETILVFDLGGGTFDVSILEVGDGVFEVKSTSGDTHLGGDDFDRRIVDYLADEFKKLEGVDLRTDRQALQRLTEAAEKAKIELSGVTQTQINLPFITAGADGAKHLDMSLTRAKFESLCADLLRRVEKPVEQALRDAKLSKENIDEVVLVGGSTRIPAVQELVKRIIGKDPNQSVNPDEVVAVGAAIQAGVLSGEVRDVVLLDVTPLSLGVETLGGVATPIIPRNTTIPTRKSETFSTAADGQTSVEIHVIQGERSMAGDNKSLGRFRLDGIPPAPRGVPQVEVTFDIDANGILSVTAKDKASGKAQTISITGASTLSKDDVAKMVNEAESFAGEDKKRREAVDLKNEADSLAYQAERQLTEFGDKVDSSDKSKIEGLIKDLREALSREDMDKVASLKADLQQAVYDLSSKLYQQSAPSGAAAGPDEGAPSGSGGTSGTRGGDDVIDAEFTETK", "output": "Acts as a chaperone."}]}
+{"id": "function_test_2443", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTTMMTDSGTASDSGAGLVDSTRNDTTTTTTTTTTPGDNDADDDNTNGTTTGHHDNNETDNNSKSYSSTHHVPAIDNTSTTNANDNEDAAGFLDRDQSPLSSISSPLSEPDNFEFDTEPIPSILSPKSTTSDNHARDGETPELDEDGQPPAKRRRVRETTPHNHSRKPKPESPPWKKFEAEGPTTIITEDGRRKSGRVNPVLLGMKPSDKKVTRKAIQTSPVSNKSSASTSRKPAPASSSNSKHAPAKMPPPPPPPKAPARKSATTHETRPSASRSRRRSPSPRRPATPPKPAAVGTRRSTRQALAHSRASYDDGQLSPGASRATPRIKLKVRPPLTVIPLVHPNQANVRPKLGPTFEEYFARAHEIPVEEGGQHIPDEEPKYTDEMALQDAKVILRVEKEVEPGGLLAPDRCSAFEPEAEEEPPRQWAHLDHLTKAMTNFRKLMYREQQLHMQAAKRIAIACEAEWRRRNPQPKTAEEIELEEMEASKAKWRQVIRAFAGTWENVRVEVNRRRLVEWEAEEQRRVKAALNQAVNLSEQKLQQRQAQVDGDEITDEDEDEDDEDLASGMPSVMGDEKESDEHSDQGSDEMSDENDEDEDEDNMSSSEDDDKKSTASDEGLTQEELRAKYANLPTLGTTDETEETTKDVEMADAPAAMDGSVANDDDTSDESVDMDDDLGSSEESDDDEEEEEDDEEEEESDDEPAGLLGLFFGKSELKKLKEEAVTEEPSVEPAGDVEMTDASAALRPELQVNGHAHEAPITNGTHTNEQLASSQTEGADDEVSLLVIPNDEIAAENTQTAAEPGSGVVEKDFLTNDSSLKYPNEIVQSENQTLPAKESVEAGGDLPMVDAPSTDDLQRETAAAPSLEAPPNTRHDSQETVAATDMQSQSQTQSPKTTDTKPTDVDTPHSELAVSVQKPDSRQSSPQPTTPTVKTEIPFLLRGTLREYQHHGLDWLAGLYANNTNGILADEMGLGKTIQTIALLAHLACHHEVWGPHLVIVPTSVMLNWEMEFKKWCPGFKILTYYGNQEERKRKRQGWNNDDVWNVCITSYQMVLQDQQVFRRRRWHYMILDEAHNIKNFKSQRWQTLLGFNTQARLLLTGTPLQNNLTELWSLLYFLAPPENGEGGFVDLTEFHNWFARPESQILESGREQLDDEARAIIAKLHKVLRPYLLRRLKADVEKQMPAKYEHVEFCRLSKRQRELYDGFLSRADTRETLQSGNYMSIINCLMQLRKVCNHPDLFVDRPIMTSFRMSRSVPADYEWKEKFIRNRLLATKPMTTVNLSFLNMIPTEYEDLSKTHTDRIAQLSSHRILLDLREAQKVRANNAYTALDPSSVKSNLVYLESAARWGRFEELQHCVYINALRRQQRPIYGKRLTEFLTLDTHLRPYKPRPRVPAKIMSWFEEDSFLLHNAIPTLQQRAESMEMTITKFACVTPAVVTGPEMNRFLLGERGIQLFEDLDLKLSAPVKYAPYMPPQPPPDPWHEARMRLTIQFPDKRLLQYDCGKLQALDKLLRKLQAGGHRALIFTQMTKVLDILEQFLNIHGHKYLRLDGATKVEQRQILTDRFNHDPRILCFILSTRSGGLGINLTGADTVIFYDQDWNPAMDKQCQDRCHRIGQTRDVHIYRLVSEHTIEANILRKASQKQMLDDVVIQEGEFTTDYFNRLSVRDVLGSNGEVIASNEDDVAANLAMDRVLGGPSTTGAGGYDGTADGGGGASQPPVRNVGRVLEMAEDREDVDAAKAAEKEIMQDEADFGEAGSTRPGTPGDGLADLDGQLLGGEENKEVEDEVIEYNAWGERMHTIDEYMLGFMAKALEGTPLELPRDRKKGRDRNRNRKGKDSRKR", "output": "Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling."}]}
+{"id": "function_test_2444", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MADYSRYTVGVLALQGAVTEHISQIESLGAKAIAVKQVEQLNQLDALVLPGGESTAMRRLMEANGLFERLKTFDKPILGTCAGLILLADEIIGGEQVHLAKMAIKVQRNAFGRQIDSFQTPLTVSGLDKPFPAVFIRAPYITEVGENVEVLAEWQGNVVLAKQGHFFACAFHPELTNDNRIMALLLAQL", "output": "Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS."}]}
+{"id": "function_test_2445", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTIIHNLGFPRIGAQRELKRAVEAYWAGRQTAEALHETGRALRAAHWQRQADAGVAFVPVGDFAWYDHILEWTTLLGAVPARFGHPEGKPVDLDTLFRMGRGRAPSGKPAAACEMTKWFDTNYHYIVPELTPGQTFRVAREDLFEQVKEAQALGHRVKPVIPGPLTWLWLGKGDAFAQGAGDIGKLQLLDALLPVYGEVLERLAGLGVEWVQIDEPALVLDLPQAWRDAYQAVYAKLAASPVKLLLATYFDGLKDNLATALALPVAGLHVDLVRAPDQLSDVASGLRPGQVLSAGVINGRNIWRTDLDAALAMLAPVREQLQERLWLAPSCSLLHVPVDLAGETELDAELLGWLSFAVQKLDELCLLGKALGGDADPAVQQGLAAQRAALQARRQSPRIHNPAVAQRMAGQAGVSRERAPFGQRIARQQSELRLPAFPTTTIGSFPQTAEIRALRRDWKSGALTDSAYENAIRKEIEEVIRFQEKVGLDVLVHGEPERNDMVEYFGELLAGFAFTKNGWVQSYGSRCVKPPIIFGDVARPAPMTVGWSAYAQSLTDKPVKGMLTGPVTILQWSFVRDDQPREATCRQLALALRDEVVDLEAAGIRVIQIDEPAIREGLPLRRADWRAYLDWAVDCFRLSTAGVGEATQIHTHMCYSEFNDIIESIAAMDADVITIETSRSNMELLKAFEDFHYPNDIGPGVYDIHSPNVPEVDWMVELMRKAAARLPKERLWVNPDCGLKTRAWPETEAALIGMVQAARTLRAA", "output": "Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation."}]}
+{"id": "function_test_2446", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAKIISFDEESRRALERGVNALADAVKITLGPKGRNVLLEKKYGTPQIVNDGITVAKEIELEDPLENTGARLIQEVASKTKDVAGDGTTTATVLVQALIKEGLKNVAAGINPVSLKRGIDKTTEALVEEIAKVAKPVEGSAIAQVATVSAGNDEEVGGMIAEAVERVTKDGVITVEESKSLTTELDVVEGMHIDRGYISPYFITNNERQTVELENARILITDKKINSIQELVPVLKKVARLGQPLLIVAEDVEGDALATLVVNKARGVLSVAAIKAPGFGERRKALLQDIAILTDGQLISEEIGLSLDTASIDALCTARTITIDKENTTIVAGTTTKPEIQKRIGQIRKQLEETDSEYDKEKLQERIAKLAGGIAVIKVGAVPETELKDRKLRIENALNATKAAVAESIGPGGGKTLIYLASKVDPIKAYFEEEEKIGADIVKRALEAPLRQIADNAGEEGSVIVSRVKDSDFNVGYNAATGEFEDLIAAGIIDPAKVVRSALQNAASIAGLVLTTEAIVVEKPEKKPAVPADPGMGGMGGMGGMGGMGGMGGMGMF", "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."}]}
+{"id": "function_test_2447", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKIVLVLAGLIALVQSSVVHPPPHVLKTKDVDTVFVERQKKVLSLFQDVDQLNTNDEYYKIGKDYDIEANIDNYTNKKAVEDFLKMYRCGFLPKYNEFSVFHDKLRDEAIALFHLFYYAKDFDTFYKSAAFARVHLNQGQFLYAYYIAIIQRKDTYGIVLPAPYEIYPELFVNIDTTYKMFRTKMQNGLINPEAAVEYGIVKEDNHYVYYSNYSNAITYYNEEQRLAYFTEDIGLNAYYFFFHIHLPFWWTAEKYGNLKERRGEMYHYFYDQLLTRYYFERLTNGLGTIPEFSWYSPVKTGHYPLLTSYYTPFSQRPNFYNVHSEENYEKIRFLDAYENYFVQALQKGVFEGFGQTIYLNDSKANSFVGNYWQDNADLYGEEVTKDYQRSYEIVARQVLGAAPKPFDKYTFMPSALDFYQTSLRDPTFYQLYNRIIGYFNQFKQYLEPHSQEKLHFVGVKVNNVVVDKLVTFFEYYDFDATNTVFLTEEELKTKYPHNLKVRQPRLNHQPFNINIDIKADVATDAVVKIFMGPKYNENGFPITLENDWMKFFEMDWFTHKITPGQNTIVRNSNEFVIFKEDSLPSTELYKLLEKGKVPFDMSEDFGYLPKRLMLPRGTKGGFPFQFVVFVYPFESTTKNLTPYEKFMIDNKPLGYPFDRPVDTSCFKQPNIFFRDVSVYHEGEYHAYEYNVPAYFSHTNKVPKE", "output": "Arylphorin is a larval storage protein (LSP) which may serve as a storage protein used primarily as a source of aromatic amino acids for protein synthesis during metamorphosis. It is a constituent of the sclerotizing system of the cuticle, and serves as a carrier for ecdysteroid hormone (By similarity)."}]}
+{"id": "function_test_2448", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRVDGREKTELRHIHIHTNYLKHPEGSVLIEVGDTKVICSATIEERVPPFMRGEGKGWVTAEYAMIPRATEQRTIRESSKGKVTGRTMEIQRLIGRALRAVVDLEALGERTVWIDCDVIQADGGTRTASITGAYVAMVLAFEKLLQAEKVSKIPVKDYLAATSVGIVEEQGVVLDLNYAEDSKADVDMNVIMTGKGQFVEVQGTGEEATFSRAQLNELLDAAEQGIFQLIDIQKEALGDIVSHIE", "output": "Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation."}]}
+{"id": "function_test_2449", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSLMLEPNPTQIKEERIYAEMGLTDEEFAMVEKILGRLPNYTETGLFSVMWSEHCSYKNSKPVLRKFPTTGERVLQGPGEGAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPVALLNSLRFGELQSPRVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDPCYEGNPLVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESSEAKRPAVQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQRETGMTPYEMMLSESQERMLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLFHKGEMVAEVPADALAEEAPIYHKPSKEAAYFAEFQQMKMETPKVENYKETLFALLQQPTIASKEWVYDQYDYQVRTSTVVTPGSDAAVVRVRGTEKGLAMTTDCNSRYIYLDPEVGGKIAVAEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLQTPVIGGNVSMYNERSGEAVYPTPTVGMVGLVHDLKHVTTQEFKQAGDLVYVIGETKAEFGGSELQKMLHGKIFGQSPSIDLDVELKRQKQVLAAIQAGLVQSAHDVAEGGLAVAISESAIGANGLGATVKLDGEATAALFAESQSRFVITVKRENKEAFEKAVEAIQVGEVTNTNEVTIHNEENEVLLTANVDEMRKAWKGAIPCLLK", "output": "Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL."}]}
+{"id": "function_test_2450", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKLSKLEKALKKVRVTPQRDDTYTIGNVLWAIRMCRLMGLDCCIDEATAAEVAILIGRFQSLDLQDSPLKGKDEKAILTTLKVLWSLLAGHHPENSDMAEKYWEAWTIRERESQKEEEGEITSIYPQLRKNFPAVSTSDGSPRYDPDLTKQLKIWADATEKHGVDHHAVNILGVITANLTQSEIRLLLQSTPQWRLDIQLIESKLNAREHAHRVWKESHPEAPKTDEIIGKGLTAAEQATLTTQECRDTYRQWVLEAALEVAQGKHDRPGPINIHQGPKEPYPEFVNKLVTALEGMAAPETTKQYLLDHLSVDHANEDCRAVLLPLGPSAPMERKLEACRAVGSSKQKMQFLAEAFAAINVKGDGEVQRCYGCGKPGHIRRDCKNQKCFKCGKPGHLQRNCKSKNGRRSSAPSGQRSGYHQEKTSVTPSAPPLVLD", "output": "Matrix protein p16 forms the outer shell of the core of the virus, lining the inner surface of the viral membrane.; "}]}
+{"id": "function_test_2451", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFNGSLVALVTPMQENGEIDYSNLKELVEWHLENDTDGLVILGTTGESPTITAEERHKIIRQVVDQVNKKIPIIVGTGANSTVHTIEMTQQAMELGADAALIVTPYYNKPTQEGLFQYFKTIAEAVPIAQILYNVPSRTACDLLPETVIRIAKCSNVVGLKEATGDIQRVKQLKAEDLDLLSGDDKTAMDFMLAGGKGVISVVANVVPKPYHAFCITAVSGNVELAKKENDQLSPLYDSLFVESNPIPVKWALSQMGVIPKGIRLPLTPLSERYHAKVRESLQQVGIKC", "output": "Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA)."}]}
+{"id": "function_test_2452", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTLLGTALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRYADAPAMHVAHRSHVINMLDGDALRRVVELEKPHYIVPEIEAIATDMLIQLEEEGLNVVPCARATKLTMNREGIRRLAAEELQLPTSTYRFADSKSLFREAVAAIGYPCIVKPVMSSSGKGQTFIRSAEQLAQAWEYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFCAPVGHRQEDGDYRESWQPQQMSPLALERAQEIARKVVLALGGYGLFGVELFVCGDEVIFSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGLPVGGIRQYGPAASAVILPQLTSQNVTFDNVQNAVGADLQIRLFGKPEIDGSRRLGVVLATSESVVDAIERAKHAAGQVKVQG", "output": "Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate."}]}
+{"id": "function_test_2453", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MMVIRPVERSDVSALMQLASKTGGGLTSLPANEATLSARIERAIKTWQGELPKSEQGYVFVLEDSETGTVAGICAIEVAVGLNDPWYNYRVGTLVHASKELNVYNALPTLFLSNDHTGSSELCTLFLDPDWRKEGNGYLLSKSRFMFMAAFRDKFNDKVVAEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLSQEAQDVIGQVHPQTAPARAVLEKEGFRYRNYIDIFDGGPTLECDIDRVRAIRKSRLVEVAEGQPAQGDFPACLVANENYHHFRVVLARTDPATERLILTAAQLDALKCHAGDRVRLVRLCAEEKTA", "output": "Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine."}]}
+{"id": "function_test_2454", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKLINAYTDGSCLGNPGPGGWAVLLRYKNNEKELVGGELDTTNNRMELMAAIMALERLSEPCQIKLHTDSQYVRQGITEWMSGWVRRGWKTAAGDPVKNRDLWERLCAATQRHMIEWCWVKAHNGDSDNERVDVLARGQAMAQRSTVASR", "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."}]}
+{"id": "function_test_2455", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNDQVIIFDTTLRDGEQALSASLTVKEKLQIAYALERLGVDVIEAGFPISSPGDFESVQTIAKHIKNSRVCALSRAVAKDIDAAAEALKVADQFRIHTFLATSTIHVQDKLRRSYDDVLEMAVNAVKHARNYTDDVEFSCEDAGRTPIDNLCRMVEAAIDAGASTINIPDTVGYTVPSEFGGIIQTLFNRVPNIDKAIISVHCHDDLGMSVANSIAAVQAGARQIEGTINGIGERAGNCSLEEIAMIIKTRQELLGVSTGIKHEEIHRTSKLVSQLCNMPIQSNKAVVGANAFSHSSGIHQDGMLKNKNTYEIMTPESIGLKNQALNLTSRSGRAAVKSHMDSMGYKEDEYNLDALYADFLKLADRKGQVFDYDLEALMHFSNLREEDDFYKLNYLSVQSGSVMATTSIKMQCGDAEMCEAAVGNGPVDALYQCIYRVTGYEIVLDKFDLTAKGEGEDGLGQADIIANYKGRKYHGTGVSTDIVEASGQALLHVINSIHRADTIAEMKQKKIATV", "output": "Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-ketoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)."}]}
+{"id": "function_test_2456", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTALKNDRFLRALLKQPVDVTPVWMMRQAGRYLPEYRASRAKAGDFMSLCMNPQFACEVTLQPLDRYPLDAAILFSDILTIPDAMGLGLYFETGEGPRFKKVISTPADIEALPVPDPQKDLGYVMDAVSTIRRELNGRVPLIGFSGSPWTLATYMVEGGSSKDFRKTKAMAYDNPQALHLLLDKLAQSVTSYLNGQILAGAQAVQIFDTWGGNLSAAAYQEFSLAYMRKIVSGLIREHEGRKVPVILFTKNGGLWLESIAEAGADALGLDWTCEIGDARRRVGDKVALQGNMDPTVLYAKPEAIRKEVARILASYGHGTGHVFNLGHGITPEVDPEHAGAFINAVHELSAQYHQ", "output": "Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III."}]}
+{"id": "function_test_2457", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTLLDTEQALLAIHTVLQLKLQQRRTREELENQGIMPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERAELVRMHILEETSAEPSLQAKQIKLKRARLADDLNEKISQRPGPMELVVKNILPVETSLKEVIIDVDYPEVVDNSSFDEDSSDALSPEQPASQESQGSIPSPIENRPSETTQIPALSPSHAFSCVQFGTDAFNQDSLQSTAITISNGLTASICKSLPALVKQSQPKPSFEKSQRIKKPKEPKPKVKKLKYHQYIPPDQKQKGTPAMDSSYAKLLQQQQLFLQLQIINQQQHQHYNYQTILPAPPKPLPDQQNTNSSSTTTVRSMSTVAPSTLATPTITRQNSNVAVGGRTGPLPHNLDEMKVAELKLELKHRGLPVSGTKIDLIERLKASQDPSTATAASAKPTPVQQAKPPEVVPIVSSSCLTTREPIKLCSTSSTPPGSPCPSEVSVVSMDEVSMISDALGETVACPVTQQVQQNPAAEKSPPDARDKDLMLREKDRQIEELTQRLKQKQELVERLRQQLEQEKRTPQHSTDDQQALILAVKQEPLPLTVDSINKKASSIVKQELNTAIICQQEPQLLIGPVSSGIEGKVDNSAGTKLVFTLTNPSSQLPEENRQIVLQKVPTPPSSLHPNNSLPKQEVLLSCCALQNQKPALQLVPGTVLSLSSSNLQPMLNMNGFQKWHGEALDSLQKQLVHNESPATPPQQPEPEPPPHSIFLTHSSPQWSKNPPGYDEAMKQQPNSCEDGRPGCLQAVDFFDVLIKNLDIPSEFKDYLVPCLKQTSPSHQAAQMVPQVEMAPPPSPIHSALGRLEDFLESSTGTPLLRGHQDGPSSMPLIDDLHSQMLSSLAILDHPPSPMDTSDLHFSPIGNSLGLDISEPPLDGMDWLELSEPPAMNLTPLSTFTPSVFSTDFLDSHDLHLHWDSCL", "output": "Transcription coactivator that associates with the serum response factor (srf) transcription factor to control expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. The srf-mrtfa complex activity responds to Rho GTPase-induced changes in cellular globular actin (G-actin) concentration, thereby coupling cytoskeletal gene expression to cytoskeletal dynamics. Mrtfa binds G-actin via its RPEL repeats, regulating activity of the mrtfa-srf complex. Activity is also regulated by filamentous actin (F-actin) in the nucleus."}]}
+{"id": "function_test_2458", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRILVEIAYQGNQFLGFQIQQQGRTVQQQFEKILKRMHKHHVRIHPSSRTDRGVHAYQQFFHFDTELNIDNKQWQYAMNRALPDDIYVKNVRNVDEYFHCRYDCVGKRYRYKVYQGNHRNPFKSGTETFVNETLDYDKMNKAAQEFIGTHDFTGFCSQKTEVESKVRTLYQSEIVATKEGFDYVVTGSGFLYNMVRVLVAFLIEVGKGKREPNDVPKLLEDKNRNNVPLTAPPDGLYLEKIYLSPEELIQEYGKDIKIHYKKSLEKH", "output": "Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs."}]}
+{"id": "function_test_2459", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTQSAGLRFRQALANSKPLQIVGTTNAYFALMAEQTGFQALYLSGAGVANASYGLPDLGMTSMNDVLIDAGRITSATQLPLLVDIDTGWGGAFNIARTIKEFEKIGVAAVHMEDQVSQKRCGHRPNKAVVSTEEMVDRIKAAVDARTDPNFVIMARTDAVAVEGLEAGIERAKAYIAAGADMIFAEALTELDQYRHFKAQVKAPILANMTEFGQTQLFNKEELAQAGADMVLYPLGTFRAANQAALKVMQALMNDGHQRNVLDTMQTRADLYKYLGYHAFEDKLDQLFSQDK", "output": "Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate via an alpha-carboxy-carbanion intermediate."}]}
+{"id": "function_test_2460", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTNIISVDTLLSASKLTCIREERILFDELSFEINAGDIVQIEGPNGAGKTSLLRILAGLSRPYAGQTFYVNEDINRCRDEYNEDLLYLGHLAGVKSELTAEENLNFNLRISGYDDFDTSAILAKVNLSGFEEALAGHLSAGQHRRTALARLWHNDCKIWILDEPFTAIDKRGVEELEQLFIKHADNGGCVILTTHQDMGIIKDDRLRKIRLDYRFV", "output": "Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system."}]}
+{"id": "function_test_2461", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNEQQRKQQSQIRTEQANVDRIKNTSSEDMIAKYFQQEYEPQSPDIKQARKRKREDVQFHYDFSIPEDMEKIGHGKKFLIRTYGCQMNEHDTEVMAGILSEMGYESTTVTEEADIILLNTCAIRENAENKVFGEIGHLKPLKLENPDLIIGVCGCMSQEESVVDRILQKHQHIDLIFGTHNIHRLPHLVKEALFGKEMIVEVWSKEGDIIENLPKARKGKIKAWVNIMYGCDKFCTYCIVPMTRGKERSRRPKDIIQEVRHLVAQGYQEVTLLGQNVNAYGKDFEDIEYGLGDLMNDIHKIDIPRVRFTTSHPRDFDDRLIEVLAQGGNLLDHIHLPVQSGSSEILKKMNRKYTREEYLELVRKIRIAMPNATLTTDIIVGFPNETEEQFEETMTLVEEVGFEAAYTFIYSPREGTPAARKKDDVPEEVKKQRLYRLNELVNKQSAASMKDYAGKKVKVLVEGESKKDPEVLAGYTEKNKLVNFKGPKSSIGKIVEVEITETKTWSLNGVMVENTVEVN", "output": "Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine."}]}
+{"id": "function_test_2462", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTDVRVRFCPSPTGTPHVGLVRTALFNWAYARHTGGKLIFRIEDTDAARDSEESYAALLDAMNWLGLNWDEGVEVGGPHEPYRQSQRSDIYQDVLKKLIDAGEVYPAYSTAEEVEERHRAAGRDPKLGYDNYDRTLTEDEITAFEAEGRKPVWRLRMPEQDWKWNDLVRGEVEFKSFTQPDFVVARSNGQPLYTLVNPVDDALMEITHVLRGEDLLPSTPRQIALYEALKRIGVAKQTPVFGHLPFVMGEGNKKLSKRDPQSDLFQHRTNGIIPEGMLNYLGLLGWSLSADQDIFTVEEFVANFDIADVLGNPARFDQKKLEAINADHIRLLPAGEFEERLRAHLSEFTDFPEDYPAEKFSFAAELVQTRIKTLAEGYDLLKFLVTADEDLVLDEKAAKKNLKEAAIEPLDAGINALEAVAEWTTPNIEAALTRALIEELGLKPRVAYGALRVAISGAAVSPPLFESMELLGRESTLTRLRAARAATPYQAAE", "output": "Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)."}]}
+{"id": "function_test_2463", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MFPMVTEFMNYGQQTVRAARYIGQGFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFDKCIACEVCVRVCPIDLPVVDWKLETDIRKKRLLNYSIDFGICIFCGNCVEYCPTNCLSMTEEYELSTYDRHELNYNQIALGRLPMSIIDDYTIRTILNLPEIKT", "output": "NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_2464", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSSRKYFGTDGIRGRVGQGVISADFVLRLGNALGRVLTAGRSKRPLVLIGKDTRISGYMFEAALEAGLVAAGADVQLIGPMPTPAIAFLTSTLRADAGVVISASHNPHYDNGIKFFSAEGEKLDDATEAAIEAALDAPFHTVESERLGKAIRTRDAIGRYIEFCKASVPRGFTLHGLKMVLDCAHGATYHIAPMLFRELGAEVVVIGAAPDGLNINDGVGSTHIDNLAAKVRETGAQLGIAFDGDGDRVLMADDQGNPVDGDDLLYVLARSWQASGRLTGTVVGTLMTNYGLEKALAALQIPFQRAKVGDRYVHQALVEGGGTLGGETSGHLLCLDRATTGDGIVSALQVLEALGRDGHSLREALSSLSKVPQQTVNVRLGGGAAKAIVEAASVQQALQQAQAAVQGRGRAFLRPSGTEPVVRVTVEADEAGLMQDTLDRLAGAVRDAA", "output": "Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate."}]}
+{"id": "function_test_2465", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAMDFIRIRGARTHNLKNIDLDLPRDKLIVITGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLSVMEKPDLDHIEGLSPAISIEQKSTSHNPRSTVGTITEIYDYLRLLYARVGQPRCPDHGFPLEAQTVSQMVDHMLTLDPEQRYMLLAPVIRDRKGEHAQVFEQLRAQGFVRVRVDGELYEIDAVPPLALRQKHTIEAVIDRFRPREDIKQRLAESFETALKLGEGMVAVQSLDDATAAPHLFSSKYSCPVCDYSLPELEPRLFSFNAPVGACPSCDGLGVAEFFDPDRVVVHPELSLSAGAVRGWDRRNAYYFQLIASLAKHYKFDVDAVWNTLPAKVRQAVLFGSGDEVISFTYFTDAGGRTTRKHRFEGILPNLERRYRETESPAVREELTKYVSQQPCPACNGTRLNRAARNVFVADRPLPELVVLPVNEALNFFRGLSLPGWRGEIASKIVKEIGERLGFLVDVGLDYLTLERKADTLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLTRLRDLGNTVIVVEHDEDAIRLADHVLDIGPGAGVHGGEICAQGTLQDILESPRSLTGQYLSGKRRIEIPKQRHKPNPKMMLHLRGATGNNLKNVDLEIPAGLLTCITGVSGSGKSTLINDTLFTLAANEINGASHTVAPHREVENLDLFDKVVDIDQSPIGRTPRSNPATYTGMFTPLRELFAQVPESRARGYSPGRFSFNVRGGRCEACQGDGMIKVEMHFLPDVYVPCDVCHGKRYNRETLEIRYKGFNISDVLQMTVEDALRLFEPVPSIARKLETLVDVGLSYIKLGQSATTLSGGEAQRVKLSKELSRRDTGRTLYILDEPTTGLHFHDIEALLGVLHKLRDEGNTVVVIEHNLDVIKTADWIVDLGPEGGHRGGTILVSGTPEDVAAHKASYTGQFLAKMLPSVKARETRPAAMANKPDARPPRKVKPEKVAKATKTATKKTAKKKAS", "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate."}]}
+{"id": "function_test_2466", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTHYEGDLRPTTARFVIIASRWNARITDALVTGARQSLAGNGIGEDAIDVVRVPGAWEIPMAANRVAQGGQHAAIIALGCVIRGDTRHYEHVADLCAEGLMSVQLQTGVPVLNGVLAVERVEDAEARAGGSHGNKGEECALAALELVNLMELLP", "output": "Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin."}]}
+{"id": "function_test_2467", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSDWSLDQARKTYSIPHWADGYFDVNAAGHVVVTPTADGPAVSLPEVVDAARAAGAKLPLLVRFPDILGQRLGKLQAAFAQAQSEWDYAGGYTAVYPIKVNQHRGVAGTLASHHGEGFGLEAGSKPELMAVLALSRPGGLIVCNGYKDREYIRLALIGRKLGLQTFIVIEKPSELTLVLEEARALDVKPGLGVRMRLASLGAGKWQNSGGDKAKFGLSPRQVLDLWKTLRDTEYADSLNLLHFHMGSQISNVRDIANGMREATRYFVELSRLGAKISHVDVGGGLGIDYEGTRSRSYCSINYGLHSYASNIVQPLASACEEHGLTPPRIVTECGRAMTAHHAVLIANVSEVEQAPEGRVPDAHDDEPAAIRHLREIHDELDVRPAVELFQEAQHFHAEGLSAYALGQIDLTHRARIDDLFYAIAHGVRARLSFDEKSHRPVLDELNERLVDKYFVNFSVFESIPDVWAIDQVFPIVPIERLNEAPQRRGIIADMTCDSDGMVKTYVENESLDSSLPLHRLNAGESYRIGFFLVGAYQEILGDIHNLFGDTDAVEVVVDRDGYRIAQQRRGDTTDVMLDYVGYQLDTLRATYAERIAAAHLSPERAQELSAALEAGLTGYTYLSDEPLG", "output": "Catalyzes the biosynthesis of agmatine from arginine."}]}
+{"id": "function_test_2468", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTTIAKILAREILDSRGNPTLEAEVTLDDGSFGRAAVPSGASTGTKEAVELRDGDKTRYLGKGVRHAVDNVNGTIAETLKNFDAADQQGLDRRLIDLDGTENKGRLGANALLGVSLAAAHAVAASRKQPLWQYLSTITEADVALPVPMMNIINGGAHADNNVDFQEFMVLPVGCSSFSEALRAGTEIFHSLKSVLKGHGLSTAVGDEGGFAPDFRSNVEALDTILEAIGKAGYTAGEDILLGLDVASSEFYDNGKYNLVGENKRLTSEQFVDFLADWVAQYPIISIEDGLAEDDWAGWKLLTDRVGKKVQLVGDDLFVTNPKIFKQGIDSGTANAILIKVNQIGTLTETLEAIAMAHAANYASIVSHRSGETEDTTIADIAVATTATQIKTGSLCRSDRVAKYNQLLRIEQALGSGARYAGRDAFVSIKR", "output": "Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis."}]}
+{"id": "function_test_2469", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKLTINKNSAKWMQLPRDVLVGHGVLEEVGDVCRDLKLKGNALIVTGSTTQDVAGKRVSRLLEDAGNSTETVLTCRATMEEVDKLMEKALNTEATFLLGVGSGRSIDLAKLASTRLEIPFISVPTAASHDGIASSRASVIDNGKNASIQAQAPLAVIADTEIISAAPYRFLAAGCGDIISNYTAVLDWELASRLRNEYFGEYAAALSRMAARVVIENADSIKPDHETSARLVVKALVSNGVAMSIAGSSRPASGSEHMFSHALDRIAPKAALHGEQCGVGTIMMMYLHGGNWQEIRDALKKIGAPTNAEELGIEDKYIIEALLQAHSIRPDRYTILGNGLTLSAAEKVARITKVIN", "output": "Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea."}]}
+{"id": "function_test_2470", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MADSRETLTINAFVVGYPIKHSRSPIIHSYWLKKFGIAGSYTAVEVSPDDFPKFIATLKEGKPGAAVGGNATIPHKEAAYRLADHPDALAEELGAANTIWMEEGKLHATNTDGYGFVSNLDERHPGWDKTQRAVVFGAGGASRAVIQSLRDRDVAEIHVVNRTVERARELADRFGPRVFSHPQAALQEVMHGAGLFVNTTSLGMNGTEAPHLDFSHLAANAVVTDIVYVPLKTPILNMAQEQGIATVDGLGMLLHQAKPGFRRWFGRIPEVDETLRSLIIADMEKH", "output": "Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)."}]}
+{"id": "function_test_2471", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDIIGGQHLRQMWDDLADVYGHKTALICESSGGVVNRYSYLELNQEINRTANLFYTLGIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLREESAWILQNSQACLLVTSAQFYPMYQQIQQEDATQLRHICLTDVALPADDGVSSFTQLKNQQPATLCYAPPLSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRDDDVYLTVMPAFHIDCQCTAAMAAFSAGATFVLVEKYSARAFWGQVQKYRATITECIPMMIRTLMVQPPSANDRQHRLREVMFYLNLSEQEKDTFCERFGVRLLTSYGMTETIVGIIGDRPGDKRRWPSIGRAGFCYDAEIRDDHNRPLPAGEIGEICIKGVPGKTIFKEYFLNPKATAKVLEADGWLHTGDTGYRDEEGFFYFIDRRCNMIKRGGENVSCVELENIIATHPKIQDIVVVGIKDSIRDEAIKAFVVLNEGETLSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCSGKIIRKNLK", "output": "Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine."}]}
+{"id": "function_test_2472", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTKKRYTLLKKDGKARRGEFVTPHGTIQTPIFMNVGTLAAIKGAVSSMDLKEIGCQVELSNTYHLHLRPGDKIVKQMGGLHNFMNWDRPILTDSGGFQVFSLAGMRKIKEEGVYFNSHIDGRKIFMGPEESMQIQSNLGSTIAMAFDECIPNPSTREYVEKSVARTTRWLERCKKEMDRLNSLDDTVNKEQMLFGINQGGVYEDIRIEHAKTIREMDLDGYAIGGLAVGETHEEMYRVIDAVVPHLPEDKPIYLMGVGLPSNILEAVERGVDFFDCVLPARNGRHGHVFTKEGKINLMNAKFELDARPIDEGCQCPACKNYTRAYIRHLFKAKEMLAMRLCVLHNLYFYNKLMEDIRDAIDGGYFAEFKAKKLEEWNGRA", "output": "Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)."}]}
+{"id": "function_test_2473", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLDLKKLRSNTEEVKKALSNRGEDFDVNVIDEVIALDEERRKILVDVEALKKQRNEVSAEIPKRKKAGEDVTEVMAEMREIGDKIKADDAKVAELNDKINYIMLRIPNIPNPAVPEGETDEDNVEIKRWGEPTKFNFEPKAHWDLGTDLDLLDFERGGKVAGSRFTVYKGMGARLERSIINYFLDKHTFENGYTEVLPPYMVNRDSMTGTGQLPKFEEDAFKVENNGYFLIPTAEVPVTNMYRNETLEGDKLPIKHAAYSACFRAEAGSAGRDTRGLIRQHQFNKVELVKFCKPEQSYEELDKLVQDAESVLQGLGLPYRIVRICKGDLGFTAALKYDIEVWMPSYNRYVEISSCSNFEDFQARRANIKYKNSPKEKPQFVHTLNGSGVAIGRTVAAILENYQQEDGSVVIPEALKEYMRCDLLK", "output": "Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)."}]}
+{"id": "function_test_2474", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTVQLRVYVPPHPLIKHWLAVARDAATPSVLFRSAITELGRWLTYEAAREWLPTEETTVQTPLEICPATVINPQVPVAVVPILRAGLGLLEGAQTVLPLASIYHLGLVRNEETLEASCYLNKLPEKFDPQTRVLITDPMLATGGSIMKAMSELTERGVDPSLVRIVSVVAAPPALQKLNAAYSGLIVYTATIDETVNDQGFIVPGLGDAGDRIFGT", "output": "Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate."}]}
+{"id": "function_test_2475", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRILGIETSCDETAASVVLRDEEGRGRILGDVVLSQLEEHSAYGGVVPEIAARAHVEALDALIEEALLRAGVTLRDIDAVAATSGPGLIGGLIVGLMTGKAIARATGKPLYAVNHLEGHALTARLTDGLSFPYLMLLVSGGHTQLILVKGVGEYERWGTTIDDALGEAFDKTAKLLGLPYPGGPAVERAAQAGNAERFDFPRPLVGDARLDFSFSGLKTAVRQAAQSLGPVTDQDIADVCASFQRAISRTLRDRVGRGLKRFRADFASVDQPALVVAGGVAANQTLRRTLQSLCDEHGFRFIAPPLQLCTDNAAMIAWAGAERLAAGLPADGLDAAPRSRWPLDSEAKALIGSGRRGAKA", "output": "Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction."}]}
+{"id": "function_test_2476", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSECFKLELKNTKPYLQDEELKNLKPAVAAAHEAIHNGTGAGNDFLGWVDLPVNYDKDEFERIKKSAEKIRNSVDAFIVIGIGGSYLGARAAIEMFSHSFSSSISKEERKNPEIFFCGNNISSTYLADLLEAIEGKDIAVNVISKSGTTTEPAIAFRIFKELLEKKYGKEEAKNRIFATTDAKKGALKTLSDNEGYETFVVPDDVGGRYSVLTAVGLLPIAVAGIDIDEMMKGAAKAREVYSEPDLEKNEAYQYAAARNALYSKGKSIEMVVNFEPSLHYFGEWWKQLFGESEGKDGKGLFPAAGDFSTDLHSMGQYIQEGRRQLIETFINVVNPKKEVTIQKDAENLDGLNFVAGKTMDFVNKQAFMGTVLAHHDGGVPVMVVNVPELTAYYFGYMVYFFEKACGISGYLLGVNPFNQPGVEAYKKNMFALLGKPGYEDLAKELNNKLK", "output": "Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate."}]}
+{"id": "function_test_2477", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSALGFPKTPSDKKALEEGAVFSPRFDPAGLVTVVVTDAEDGMLLMVAHMNAQALALTLETGIAHYWSRSRNALWKKGETSGNFQHVVEMRTDCDQDALWLRVKVLGHDATCHTGRRSCFYRTVGLVDGKGTLVDDGSKPLFDAEFTYRKPSS", "output": "Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP."}]}
+{"id": "function_test_2478", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSKRQKAFHDSLANEKTRVRLYKSGKNWVKSGIKEIEMFKIMGLPFISHSLVSQDNQSISKKMTGYGLKTTAVIGGAFTVNMLHDQQAFAASDAPLTSELNTQSETVGNQNSTTIEASTSTADSTSVTKNSSSVQTSNSDTVSSEKSEKVTSTTNSTSNQQEKLTSTSESTSSKNTTSSSDTKSVASTSSTEQPINTSTNQSTASNNTSQSTTPSSVNLNKTSTTSTSTAPVKLRTFSRLAMSTFASAATTTAVTANTITVNKDNLKQYMTTSGNATYDQSTGIVTLTQDAYSQKGAITLGTRIDSNKSFHFSGKVNLGNKYEGHGNGGDGIGFAFSPGVLGETGLNGAAVGIGGLSNAFGFKLDTYHNTSKPNSAAKANADPSNVAGGGAFGAFVTTDSYGVATTYTSSSTADNAAKLNVQPTNNTFQDFDINYNGDTKVMTVKYAGQTWTRNISDWIAKSGTTNFSLSMTASTGGATNLQQVQFGTFEYTESAVTQVRYVDVTTGKDIIPPKTYSGNVDQVVTIDNQQSALTAKGYNYTSVDSSYASTYNDTNKTVKMTNAGQSVTYYFTDVKAPTVTVGNQTIEVGKTMNPVVLTTTDNGTGTVTNTVTGLPSGLSYDSATNSIIGTPTKIGQSTVTVVSTDQANNKSTTTFTINVVDTTAPTVTPIGDQSSEVYSPISPIKIATQDNSGNAVTNTVTGLPSGLTFDSTNNTISGTPTNIGTSTISIVSTDASGNKTTTTFKYEVTRNSMSDSVSTSGSTQQSQSVSTSKADSQSASTSTSGSIVVSTSASTSKSTSVSLSDSVSASKSLSTSESNSVSSSTSTSLVNSQSVSSSMSGSVSKSTSLSDSISNSNSTEKSESLSTSTSDSLRTSTSLSDSLSMSTSGSLSKSQSLSTSISGSSSTSASLSDSTSNAISTSTSLSESASTSDSISISNSIANSQSASTSKSDSQSTSISLSTSDSKSMSTSESLSDSTSTSGSVSGSLSIAASQSVSTSTSDSMSTSEIVSDSISTSGSLSASDSKSMSVSSSMSTSQSGSTSESLSDSQSTSDSDSKSLSLSTSQSGSTSTSTSTSASVRTSESQSTSGSMSASQSDSMSISTSFSDSTSDSKSASTASSESISQSASTSTSGSVSTSTSLSTSNSERTSTSVSDSTSLSTSESDSISESTSTSDSISEAISASESTSISLSESNSTSDSESQSASAFLSESLSESTSESTSESVSSSTSESTSLSDSTSESGSTSTSLSNSTSGSASISTSTSISESTSTFKSESVSTSLSMSTSTSLSNSTSLSTSLSDSTSDSKSDSLSTSMSTSDSISTSKSDSISTSTSLSGSTSESESDSTSSSESKSDSTSMSISMSQSTSGSTSTSTSTSLSDSTSTSLSLSASMNQSGVDSNSASQSASNSTSTSTSESDSQSTSTYTSQSTSQSESTSTSTSLSDSTSISKSTSQSGSTSTSASLSGSESESDSQSISTSASESTSESASTSLSDSTSTSNSGSASTSTSLSNSASASESDSSSTSLSDSTSASMQSSESDSQSTSASLSDSLSTSTSNRMSTIASLSTSVSTSESGSTSESTSESDSTSTSLSDSQSTSRSTSASGSASTSTSTSDSRSTSASTSTSMRTSTSDSQSMSLSTSTSTSMSDSTSLSDSVSDSTSDSTSASTSGSMSVSISLSDSTSTSTSASEVMSASISDSQSMSESVNDSESVSESNSESDSKSMSGSTSVSDSGSLSVSTSLRKSESVSESSSLSGSQSMSDSVSTSDSSSLSVSTSLRSSESVSESDSLSDSKSTSGSTSTSTSGSLSTSTSLSGSESVSESTSLSDSISMSDSTSTSDSDSLSGSISLSGSTSLSTSDSLSDSKSLSSSQSMSGSESTSTSVSDSQSSSTSNSQFDSMSISASESDSMSTSDSSNISGSNSTSTSLSTSDSMSGSVSVSTSTSLSDSISGSTSVSDSSSTSTSTSLSDSMSQSQSTSTSASGSLSTSISTSMSMSASTSSSQSTSVSTSLSTSDSISDSTSISISGSQSTVESESTSDSTSISDSESLSTSDSDSTSTSTSDSTSGSTSTSISESLSTSGSGSTSVSDSTSMSESDSTSVSMSQDKSDSTSISDSESVSTSTSTSLSTSDSTSTSESLSTSMSGSQSISDSTSTSMSGSTSTSESNSMHPSDSMSMHHTHSTSTSRLSSEATTSTSESQSTLSATSEVTKHNGTPAQSEKRLPDTGDSIKQNGLLGGVMTLLVGLGLMKRKKKKDENDQDDSQA", "output": "Mediates binding to human platelets, possibly through a receptor-ligand interaction. Probably associated with virulence in endovascular infection (By similarity)."}]}
+{"id": "function_test_2479", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTLEINFDGLIGPTHNYAGLSLGNIASHSNAGAVSSPRAAALQGLTKMRTLLDLGLTQGFLPPPPRPAAHVLRRLGFKGSDQAVLAQVADEDLDLLRAASSASSMWTANAATVLAAPDTADGRVHLVTANLGTMLHRSLEADDTYATLRRVFSGEAFAVHAPLPFAAHLGDEGAANHMRLAANHGARGVNVFVHGAPRGGRFPERQALRASQAAARLAGVQPTALFAMQSAEAIKAGAFHNDVVAVANANVLLAHPQAFATRPDLLAELSARLPGLVVIETRDLSLEDAVASYLFNSQLVSLPDGYMALIVPVEARDNAAAWREIQTILAADNPVTKVKVVDLRQSMSNGGGPACLRLRVPVAAAARDQINPAFLLDHARLDRLTRLVETWWPRAIAPSDLTDPALWEAAMVAHAALETFLTAPTV", "output": "Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2)."}]}
+{"id": "function_test_2480", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIRYYQQQLADLKAQNQFRQLPQLIHRGRFIQREDNTMLNMSSNDYLGLANNEALRQAFFTQYQDQLPALTSSSSRLLTGSFPIYDELESLMAQAFGRETALLFNSGYHANIGILPALADKKTLIVADKLVHASMIDGIRLAQCEFVRFRHHDYAHLEQILQKNDRTFERIIVVTESVFSMDGDCADLTQLVALKQRYPQVMLYVDEAHAIGVLGEKGLGLAEQQGCINQIDILVGTFGKALGSMGAYVICDQVIRDYLVNKMRPLIFSTALPPFNVAWTHFVFQQLPHLQAERAHLAQLSQHLRQAIVDIFQVPMPSESCIVPYILGDNELTVRTAQRLQQQGYYCLPIRPPTVPKGTSRIRFSLTADMQVAEVEQFIACLQELAE", "output": "Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide."}]}
+{"id": "function_test_2481", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRALLLSGCLALVLLTQQAAAQTLLVVGDSISAALGLDTSQGWVALLQKRLADEGYDYRVVNASISGDTSAGGLARLPALLAEEKPALVVIELGGNDGLRGMAPAQLQQNLASMAQKARAEGAKVLLLGIQLPPNYGPRYIEAFSRVYGAVAAQEKTALVPFFLEGVGGVQGMMQADGIHPALAAQPRLLENVWPTLKPLL", "output": "Esterase that exhibits the highest activity towards Tween detergents and p-nitrophenyl esters of short acyl chain length. Also displays a low thioesterase activity towards palmitoyl-coenzyme A, but is not active towards acetyl-coenzyme A."}]}
+{"id": "function_test_2482", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNRLYPHPIIAREGWPIIGGGLALSLLVSICCGWWSLPFWVFTVFALQFFRDPAREIPLNPEAVLSPVDGRIVVVERARDPYRDVDALKISIFMNVFNVHSQKSPADCTVTKVVYNKGKFVNADLDKASTENERNAVLATTASGREITFVQVAGLVARRILCYTQAGAKLSRGERYGFIRFGSRVDMYLPVDAQAQVAIGDKVTGVSTVLARLPLTAPQTESEPESEPALQTAPVETAANPSAEQRQIEAAAAKIQAAVQDVLKD", "output": "Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)."}]}
+{"id": "function_test_2483", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEVVIVPDAKAGGELIAEAMAQLLRRKPDALLGVATGSTPLPVYEALAAKVRSGAVDTAQARIAQLDEYVGLPAEHPESYRSVLRREVLEPLGIDMDAFMGPDGTAADVQAACEAYDTALGGSGGVDLQLLGIGTDGHIGFNEPCSSLASRTRIKTLTEQTRIDNARFFDGDIEQVPHHVITQGIGTILEARHVVLLATGEGKADAVAASVEGPVAAVCPASALQLHPHATVVVDEAAASKLKLADYFRHTYAHKPDWQGI", "output": "Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion."}]}
+{"id": "function_test_2484", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGVFTFEDESTSTIAPARLYKALVKDADAIIPKAVEAIQSIETVEGNGGPGTIKKLTLIEGGETKYVLHKIEAVDEANLRYNYSIVGGVGLPDTIEKISFETKLVEGANGGSIGKVTIKIETKGDAQPNEEEGKAAKARGDAFFKAIENYLSAHPEYN", "output": "Class II ribonuclease (RNase) (By similarity). Binds to cytokinins (By similarity). Interacts with melatonin (By similarity)."}]}
+{"id": "function_test_2485", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDVNSRAKIRPLDQLVINKIAAGEIIERPENAIKELIENSLDAGSTSIDVLLKDGGLKLLQITDNGSGIQYDDLPYLCQRFSTSKIDNFNDLQHLQTFGFRGEALASISHVAKVTVVTKLSSDIHAWKAFYVDGALAPISPGMSPAPQPCAGKQGTVITAEDLFYNVRSRKSALKNGSEEFRRIMILVQKYAIHNDQVSFNCKKVGDTVASLSLSSRLSKADKIRHIYGPRVASHLRDFSLGEGQSSIVGFSANGFISNADFQDKKSNLILFINNRLVESVELRHALEETYAKYLHKGASYFVYLSLNMSPEQLDVNVHPSKRIVHFLYDQEIATSICDKLGEILERTDTERSYPLQAMIPSISNTKNAESSSQKAVRTYENYLVRTDPRERSIKSMLSDNFLQRSSNNYDNEIIEKVDSANSNKNATNDIKDLQTEEIVEEGNSIDLESIKSLQKQVINSMHVLATNILTEHKYVGLVCPTRRIAAVQHNIGLYVVDYGKLSYHLFYQICLTEFGNYGEFVLETPLSISDLFEIVNGDEDKSESEKFTRLLVSRRDMLKDYFSISVTSGGLLTAVPMLSPKYHPPFEQLPLLISSLTPKFFDWLDEKSCLNGIMKAIAKFYVPLPLSYEESDVKSIRSLESCLEDYLFPEFRRRVICPKKVFEEKCIYQITSLPRLYNVFERC", "output": "This protein is involved in the repair of mismatches in DNA."}]}
+{"id": "function_test_2486", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEVMSVIPYVIEQTGRGERSYDIYSRLLKDRIIFVGTPVESQMANSIVAQLLLLDSQNPEQEIQMYINCPGGEVYAGLAIYDTMRYIKAPVSTICVGMAMSMGSVLLMAGDKGKRMALPNSRIMIHQGSAGFRGNTPDLEVQAKEVLKLRDTLVDIYHKHTDLPQEKLLRDMERDYFMSPEEALKYGLIDQVIDQTRENRGGEE", "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins."}]}
+{"id": "function_test_2487", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAAVTGLYGSIDEFLNHCSQSGDSAYSALRSLLERLEKPDTRTEARIFLAHLQKKLDNDGASQRCLETYHFQIQDIYLDRNEGTGYQNRKKFTMMVIPSIFMPEDWSFTFYEGINRHPDSIFKDKTVAELGCGNGWISIAIAEKWLPLKVYGLDINPRAVKISWINLYLNAFDEDGQPVYDSESKTLLDRVEFYESDLLSYCRDNHIELERIVGCIPQILNPNPDAMSKLVTENASEEFLHSLSNYCALQGFVEDQFGLGLIARAVEEGIDVIKPMGIMIFNMGGRPGQGVCKRLFERRGLSVNKLWQTKILQASDTDISALVEIEKNNPHRFEFFMGLVGDRPICARTAWAFGKACGRISHALSVYSCQLRHPNEVKKIFEFLKNGFHDISNSLDLSFEDDSVADEKIPFLAYLAGVLKDGSRFPYEPPTGNKRFRDLIASFMKTYHHVPLSTDNVAIFPSRATAIENSLRLFTPRLAIVEEHLTCNLPRQWLTSLEIEQTRDSKTPIDGITVIEAPRQSDLMIELIKKLKPQVVVTGIAQFEAVTSSAFEHLLRVTREIGSRLFIDISDQFELSSLPSSIGVLKYLARTPLPSHAAIICGLLRNRVYTDLEVAFVISEEQTIFDALTRTVELLQGNTALISQYYYGCLFHELLSFQIPDRRQTAEREAENVEASDIDMIGFSSSAISVLSQSELSVRVTEKSSLLHMDVDQIFLPTPTPVKAAIFESFARQNVTETECDVTPILRQFILNTWNFSVEHSAEFIYADFPLALFNKLVLCCIEEGGSLCMPAGSNGNYAAAAKFLNANIMSIPTEAEVGFKLTAKQLSSVLETVHKPWVYISGPTINPTGLLYSNEEMKSLLTVCARYGARTIIDTSFSGIKFNSQDWDGWNLDASLAGLTGNPSFSVCLLGGLFFKIPTGGLSYGFLVLKSGFLADSFRSSFSGLNKPHNTVRYTAKKLLELGEQKGNLTGAAQGQEKLLATRLKRLKETLENCGWEVIEARGGVSVIAKPSAYLGKNIKLEKDGSTWVTKLDGTNIREAMLRATGLCINGPSWTGIPDYCRFTFALEDGDFDRALDCIVKFNQLVK", "output": "Catalyzes the S-methylmethionine (SMM) biosynthesis from adenosyl-L-homocysteine (AdoMet) and methionine. SMM biosynthesis (by MMT1) and degradation (by HMT-1, HMT-2 and HMT-3) constitute the SMM cycle in plants, which is probably required to achieve short term control of AdoMet level. Also able to catalyze the selenium-methylmethionine (SeMM) from AdoMet and selenium-methionine (SeMet). May play a role in phoem sulfur transport; such function is however not essential."}]}
+{"id": "function_test_2488", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTIALGKFTKDENDLFDIMDDWLRRDRFVFVGWSGLLVFPCAYFALGGWFTGTTFVTSWYTHGWASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGFWTFVALHGAFGLIGFMLRQFELARSVQLRPYNAIAFSAPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL", "output": "Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors. D2 is needed for assembly of a stable PSII complex."}]}
+{"id": "function_test_2489", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAVQRTLLVVKPDGVERGLIGEVVSRVERKGLKIVAMKMMRLTREKAEEFYSVHRDKPFFGELVEFITSGPVVAMVVEGDEAVSVVRLMIGSTDGRKAAPGTIRGDFSLDIMKNIVHASDSPESFEREFRVLFSESEIVEW", "output": "Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate."}]}
+{"id": "function_test_2490", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAEKPHMNLVVIGHVDHGKSTLVGHLLYRLGYIEEKKLKELEEQAKSRGKESFKFAWILDKMKEERERGITIDLTFMKFETKKYVFTIIDAPGHRDFVKNMITGASQADAAILVVSARKGEFEAGMSTEGQTREHLLLARTMGIEQIIVAVNKMDAPDVNYDQKRYEFVVSVLKKFMKGLGYQVDKIPFIPVSAWKGDNLIERSPNMPWYNGPTLVEALDQLQPPAKPVDKPLRIPVQNVYSIPGAGTVPVGRVETGVLRVGDKVVFMPPGVVGEVRSIEMHYQQLQQAEPGDNIGFAVRGVSKSDIKRGDVAGHLDKPPTVAEEFEARIFVIWHPSAITVGYTPVIHVHTASVSSRIIEIKAKLDPKTGQVVEQNPQFLKAGDAAIVRFKPVKPLVVEKFSEIPQLGRFAMRDMNRTVGIGIVTDVKPAKVDIKAK", "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."}]}
+{"id": "function_test_2491", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEKDLHLHEKKCLAHEAATQVTSGMILGLGSGSTAKEFIFALAHRIQTESLAVHAIASSQNSYALAKQLAIPLLNPEKFSSLDLTVDGADEVDPQLRMIKGGGGAIFREKILLRAAKRSIILVDESKLVPVLGKFRVPLEISRFGRSAIIEEIRHLGYEGEWRLQDTGDLFITDSSNYIYDIFSPNSYPNPEKDLLKLIQIHGVIEVGFVIEKVEVWSSNSQGLISKKYSV", "output": "Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate."}]}
+{"id": "function_test_2492", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MVESKFTIGDRTFTSRLIMGTGGAANLAILEEALIASGTELTTVAIRRVDTDGGSGLLKLLSRLDIMPLPNTAGCRSAAEAVLTAQLAREALNTNWIKLEVIADERTLLPDGLELVRAAEQLVDAGFVVLPYTNDDPALAHRLEGTGCAAVMPLGSPIGTGLGINNPHNIEIIVAQARVPVVLDAGIGTTSDAALAMELGCDAVLLASAVTRAVDPPTMAAAMASAVTAGYLARRAGRIPKRFWAQASSPELMRTGEELGN", "output": "Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S."}]}
+{"id": "function_test_2493", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSSINKKELEKFEKISHNWWNKNGEFGILHRINHIRIEYIIEKIKSNYNDISKLQILDVGCGGGLIAAPLALQGFNVTAIDALKSNVETATIYAQKNGLKINYLQATIEELENDKLYDVVICLEVIEHVANIQQFILNLVQHIKPNGIAIISTMNRTKKAYLFGIIVAEYILGWVPKNTHDYSKFVKPSEIYEILTDTNIEIKELKGLVFNLAKNEWKLSNDIDVNYFMCLEKKMNSLSSTCNGIPQLKRVI", "output": "O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway."}]}
+{"id": "function_test_2494", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKQLFLIIGAPGSGKTTDAELIAKNNSETIAHFSTGDLLRAESAKKTERGLLIEKFTSQGELVPLEIVVETILSAIKSSSKGIILIDGYPRSVEQMQALDKELNAQNEVILKSVIEVEVSENTAKERVLGRSRGADDNERVFHNRMRVFLDPLVEIQNFYKAKHLHKIINGERSIEEIVNEMQKYILSFAN", "output": "Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism."}]}
+{"id": "function_test_2495", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLGSVKKTLFGVLCLGALCLRGLMAEPDAKELVSLGIESVKKQDFAQAKAHFEKACELKEGFGCVFLGAFYEEGKGVGKDLKKAIQFYTKGCELNDGYGCRLLGNLYYNGQGVSKDAKKASQYYSKSCELNHAEGCTVLGSLHHYGVGTPKDLRKALDLYEKACDLKDSPGCINAGYMYGVAKNFKEAIVRYSKACELKDGRGCYNLGVMQYNAQGTAKDEKQAVENFKKGCKSSVKEACDALKELKIEL", "output": "Slowly hydrolyzes 6-aminopenicillinic acid and 7-aminocephalosporanic acid (ACA) derivatives. May be involved in the synthesis of the cell wall peptidoglycan (By similarity)."}]}
+{"id": "function_test_2496", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MASQEHPNWLTALLADTRPPPKLFAWSPANIQPKLDEGIDMGSSNSDEEYDNDACVCPSTDSDQRIYIIGPGNIGRLYATHMARHPNALPITLVVHRKELLSQWAACEGVGLADLTSGKIFLNKRFTVEWWTETRPPYGPVKEVADGKKLHNVFISTKAEAGLSEADRIRRYLGRCSSVVFAQNGVCKLWPPHGPLYISHRYPSGDTPTFSACVVSHGVASAGPFLSVHAAPADAYIGPVFWASDPESPWRQPSDDFFIRHIATTPLVNTKQVSSGEIWLLQLEKLVMNAAINPLTALLRYKTGELFTSYGSDDPLARVIDKLLWQTSAVIQGLIDHETSHSVITSYAEQMSQPGTSCSVPKVRKKLTERFSQPILKAKLYAFGLKIFEHRSSMLQDIEAGRKTEIRDFNGWIVDTACFLGTGLDVSVHSGLTGLIERCERFDKMELGRALL", "output": "Ketoisovalerate reductase; part of the gene cluster that mediates the biosynthesis of beauvericin (BEA), a non-ribosomal cyclic hexadepsipeptide that shows antibiotic, antifungal, insecticidal, and cancer cell antiproliferative and antihaptotactic activity . Ketoisovalerate reductase BEA2 catalyzes the NADPH-specific reduction of ketoisovaleric acid to hydroxyisovalerate, a precursor for beauvericin biosynthesis (By similarity). The nonribosomal cyclodepsipeptide synthetase BEA1 then catalyzes the formation of beauvericin via condensation and cyclization of 3 dipeptidol monomers, each composed of one unit of hydroxyisovalerate and one unit of N-methyl-phenylalanine (By similarity)."}]}
+{"id": "function_test_2497", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSAEAACSDDSFGPWAGATCRGGFDFTLLFEETILSILPSVLVIVVAPIPIIRLAREPPKVRASALDWFKKISSICFITLSAALVGLWARNSTITQTRASTPSAVLTFVLSLVYVLLSTIEHRLSLRPSSVLSFYLGLSVLFDIARTRTLFMLEDATHSAIPPVFASSLALRVVMLLLESTEKRSLLLAKYDNAAPESVGGPYNLGVFYWLSTLFFTGYRKILEIGDLYPLDDELRSTGLAKKMSDAWRKVPDKAAPNVLFATWLKTFSKAMFMPVVPRLFQIGFTYAQPFLITAAIELAATPQTQPYNNNGYGLIGAYILVYSGIAVSVGQYEWRNYRAATMMRGSIIPLVYEKSLILDSCSSATFHPTAALTLVSTDIETITSGLVQIHETWSNLVEIGLAIYLLERQLGAACVMSVGFAIVVMVGTVFLARPTGTHLAAWIQASQVRVIETSKALASIKWLKISGLTDVAFSVIQKLRKQELVVSEKFRYLLGLSLILSICTPILGPLLTFAVFAGIAAHGGSTLTIAKVFTAFSIIVLLNSPLAKIVQALPQISGSIASFQRIQDHLNAEERHDPRSTTTGTSPESNNGSQQTLSDKQATADGDTMISISGKFSWRSETPAPGTGITLVTGSDEGHLADTTPDANGDSRDAPVIDISPRLDIPRGALTLILGPVGCGKSTLLKALLGELSSFDGVIEAKYSGAVTYCDQNPWLPNETVRDIIRGRSATDTSDADSSEKADHDEDWYRVVVSACELQRDMQIWPRGDRTPVGSKGISMSGGQKQRLSIARAVYARRALVILDDVFSGLDANTEDVVFENLLGNSGILRKANMTVVLASSDVRRVPFADKIVLLNQHGQVQHTGTPGDLKQVAELGWADRDLDAQQEKPGKDELNHEHGEYSESAPEKLRRSQTNHGADNNAAVQEVLQAVESQADTARQMGDSAVYKFYVKSAGWLTITIFVIAICVYAFCDSFPSVWLKWWAEANEKNPNSDLGKWLGVYAVLGVGAVAACLIGTWQLFIITINRSGLYFHNLLVETVSRAPMMFHSTTDTGITVNRFSQDLQLIDMELPSAALGVVMALSFGIAQFILVCVSSRYMAALLPFLLAVLYAIQHFYLRTARQLRLLDIEYKAPLYTQLMETISGVVTIRAFRWETQSTEKAIRILDTSQKPSYLLFCVQRWITFAVNMVIMMLAVILIVLTTTLREAIGPGYVGIALSNILAFSATMQATITSWVTLEIALGAVARIRSFSMQVRSEDDEARDGLAKAGLDARLVQPTPETVGERWPSQGRIELDNVTASYPSSGRVLHNITMIIEPGQKVAICGRTGSGKSSLFLSLLGLIAQDSGSITIDSVDLATLPREYLRSQIVAVPQEAYILDGTVRLNADPYHNKETLGSTDPPDSRDEQIIDVLKRVGLWEKIATRGGLDMVIDDKFLSQGQAQLMVLARAMLRRDESRVLLLDEATSSLDEATTTLIDEIVSTWFKDWTVLAIAHKLDAILDYDRVAVLDAGRLVEYDQPRELLQRPTSIFKELYLLSTNQASLSSPDSN", "output": "ABC multidrug transporter; part of the gene cluster that mediates the biosynthesis of the lipopeptide antibiotics leucinostatins that show extensive biological activities, including antimalarial, antiviral, antibacterial, antifungal, and antitumor activities, as well as phytotoxic . May be involved in the efflux of leucinostatins (Probable)."}]}
+{"id": "function_test_2498", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MISPIKNIKNVFPINTANTEYIVRNIYPRVEHGYFNESPNIYDKKYISGITRNMAQLKIEEFINEKSRRLNYMKTMYSPCPEDFQPISRDEASIPEGSWLTVISGKRPMGQFSVDSLYHPDLHALCELPEISCKIFPKENSDFLYIIVVFRNDSPQGELRTNRFIELYDIKREIMQVLRDESPELKSIKSEIIIAREMGELFSYASEEIDSYIKQMNDRFSQIKARMSVT", "output": "Cysteine methyltransferase effector that inhibits host cell NF-kappa-B activation by preventing nuclear translocation of host protein RELA/p65 . Acts by mediating cysteine methylation of host proteins TAB2 and TAB3: methylation of a conserved cysteine residue of the RanBP2-type zinc finger (NZF) of TAB2 and TAB3 disrupts zinc-binding, thereby inactivating the ubiquitin chain-binding activity of TAB2 and TAB3, leading to NF-kappa-B inactivation. Also mediates cysteine methylation of host protein ZRANB3, inactivating its ability to bind ubiquitin chains (By similarity)."}]}
+{"id": "function_test_2499", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLSVDLPSVANLDPRIAAAAAGSAVAVYKLLQLGSRESFLPPGPPTRPVLGNAHLMTKMWLPMQLTEWAREYGEVYSLKLMNRTVIVLNSPKAVRTILDKQGNITGDRPFSPMISRYTEGLNLTVESMDTSVWKTGRKGIHNYLTPSALSGYVPRQEEESVNLMHDLLMDAPNRPIHIRRAMMSLLLHIVYGQPRCESYYGTVIENAYEAATRIGQIAHNGAAVDAFPFLDYIPRGFPGAGWKTIVDEFKDFRNSVYNSLLDGAKKAMDSGIRTGCFAESVIDHPDGRSWLELSNLSGGFLDAGAKTTISYIESCILALIAHPDCQRKIQDELDHVLGTETMPCFDDLERLPYLKAFLQEVLRLRPVGPVALPHVSRENLSYGGHVLPEGSMIFMNIWGMGHDPELFDEPEAFKPERYLLTSNGTKPGLSEDVNPDFLFGAGRRVCPGDKLAKRSTGLFIMRLCWAFNFYPDSSNKDTVKNMNMEDCYDKSVSLETLPLPFACKIEPRDKMKEDLIKEAFAAL", "output": "Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of pleuromutilin, a tricyclic diterpene showing antibacterial properties . The geranylgeranyl diphosphate (GGPP) synthase ple4 catalyzes the first step in pleuromutilin biosynthesis . GGPP is then substrate of the premutilin synthase (PS) ple3 to yield premutilin . Premutilin synthase is a bifunctional enzyme composed of the fusion of a class II diterpene cyclase (DTC) and a class I diterpene synthase (DTS), with the corresponding domains and active sites containing characteristic aspartate-rich motifs (By similarity). GGPP is first converted to mutildienyl-diphosphate (MPP) at the class II DTC site (By similarity). MPP is subsequently further cyclized at the class I DTS site, followed by a 1,5-hydride shift and addition of water prior to terminating deprotonation, to yield premutilin (By similarity). The cytochrome P450 monooxygenases ple5 and ple6 hydroxylate premutilin at C-11 and C-3, respectively, producing 11-hydroxypremutilin and 3-hydroxypremutilin . The combination of the actions of both ple5 and ple6 leads to the production of 3,11-dihydroxypremutilin . The short chain dehydrogenase ple7 further converts 3,11-dihydroxypremutilin into mutilin . The acetyltransferase ple2 then acetylates mutilin to produce 14-O-acetylmutilin . Finally, the cytochrome P450 monooxygenase ple1 catalyzes hydroxylation on the alpha position of the acetyl side chain of 14-O-acetylmutilin to yield pleuromutilin ."}]}
+{"id": "function_test_2500", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLDIKKIKEILPHRYPFLLVDRVISVEEGKKVTAIKNVTANEEFFNGHFPEYPVMPGVLIVEALAQTSGIAMMQSEANKGKIGLFAGIDGCRFKRQVIPGDQLLLEAEITRMRGAIAKAKVKATVEGDLVCEAEIMFALSDLPK", "output": "Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs."}]}
+{"id": "function_test_2501", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEIGQYQPNLEGDGLRIGIVQSRFNEPVCNGLADACVEELERLGVTGEDVLLVSVPGALEIPLALQKLAESGQFDALIALGAVIRGETYHFELVSNESGAGITRIGLDFNLPIANAVLTTENDEQAVARMTEKGRDAARVAVEMANLTMALDQLGDDEDEEEDEDDEEERA", "output": "Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin."}]}
+{"id": "function_test_2502", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MMIDIPDDRLVAGVDEVGRGPLVGDVVTAAVILDPANPIIGLNDSKKLSEKKRLALFDEIKEKALAWSVGRASPAEIDELNILHATMLAMQRAVAGLSIAPELVFIDGNRCPSLSMEARAVVKGDSLVAAISAASILAKVTRDAEMTELDSRHPEYGFARHKGYPTAEHLAILAERGPLPEYRKSFKPVRRALGIE", "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."}]}
+{"id": "function_test_2503", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKDLLKFLKAQTKTEEFDSIKIGLASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMTLRDIERVLYFESYVVIEPGMTNLERSQMLSEEQYLDALEEWGDEFDAKMGAEAILALLRAIDLEGEVRTMREELDQTNSETKRKKTTKRLKLMEAFLQSGNKPEWMIMTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIYGKLESRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPTLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPASGEPIIVPSQDVVLGLYYMTRARINAKGEGMVLSGPKEAEKVYRAGLADLHARVKVRITEYLRQEDGSLRAHTEMKNTTVGRAILSLILPKGMEYALIDEPKVLTAAEQADLDANPQNWIKSVSNKALGKKLISRLLNTCYRKQGLKDTVIFADQLMYTGFHYAALSGASVGIDDMVIPDAKKDIIAAAEAEVAEIQDQFLSGLVTAGERYNKVIDIWASANERVSKAMMENLSKERNVNSLGEEEEQASFNSIFMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPIVANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDMVITEDDCGTTEGLWMTPLIEGGDVVEPLRERVLGRVVADDVIKPGTEDEVLVARNTLLDEQLCDLLERNSVDRVKVRSAITCETDFGNCAHCYGRDLARGHLVNKGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNTGSIKLQNAKFVHNSDDKLVITSRSTELTIMDEMGRTKESHKLPYGSVLEVKDGQAVNAGETVANWDPHTHPIITEVAGRLHFEHMIDGVTITRQTDELTGLSSIVVLDVNERPSAGKEMRPTVKLVDLNGKDVMIPGTDVAAQYFLPGKAIVNLEDGANVGVGDAVARIPQESGGTKDITGGLPRVADLFEARQPKEPAILAEISGTISFGKETKGKRRLVITPTDGGDVYEEMIPKWRNLNVFEGEKVEKGEVLADGPESAHDILRLRGISPVANYIANEVQDVYRLQGVKINDKHIEVIVRQMLRKCEILSAGDTDLIEGEQVEVARVKIANRKLVAEGKTPATFRHILMGITKASLSTESFISAASFQETTRVLTEAAVGGKRDELRGLKENVIVGRLIPAGTGFAYHHGRINQRAAAARAVGVPQVTADEAQQNLADLLNAAGSFDEE", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_2504", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLRTMLKSKIHRATVTQADLHYVGSVTIDADLMDAADLLEGEQVTIVDIDNGARLVTYAITGERGSGVIGINGAAAHLVHPGDLVILIAYGTMQDAEARAYQPRIVFVDADNKQIDVGHDPAFVPAFDIPGAEELLNPRIGAR", "output": "Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine."}]}
+{"id": "function_test_2505", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIRIGIHGASGKMGYEIISNLKNNEQAILSVAYTIEPMPFDVGDAIVTNDLKTLFDNSDVIIDFSIKDGAVNLINYARTNPKPLIIGTTGLGSEGDELIKLASSVMPILQATNMSLGVAVLNRLTEFASRVLDGFDIEIVEMHHRRKVDAPSGTALTLATHAAKARNLTLDSVRVSGRDGMIGARSKDEIAVMSLRGGDIVGRHTVGFYNDGEFIELNHTATSRATFAKGAIKAAIWIKSKEPKLYSIYDCLGL", "output": "Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate."}]}
+{"id": "function_test_2506", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLFLGSGELGKEVTIELMRLGAWVCAADSYAGAPAQQVAHEYRVLDMANADQLRALFDEIQPDIIVPEVEAIATSELAAAAARGAQVVPSAEIAAICMDRERLRVLAHEELGLPTTPYRFAGSLEELREGAQIVGYPCVVKPIMSSSGHGQSVVRSADAIDAAWTEAQEGRRAHDEGDVSRVIVEALAPLDYELTVLTVSSSAGIVTCAPIGQRQESGDYRESWQPATFTPDVLEQAQHIARTAVEGLVAKAQASGEKGWGVFGVELFVLTDGNVLFNEVSPRPHDTGMVTMASQRLSEFALHARAILGLPITQEHVALSIPEGTVAASHAIVVQGDGEAEFRNVAAALAEPGTDLRVFAKPEVHGHRRMAVALAVGGDEADARAKAGNVAESLDIAIV", "output": "Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate."}]}
+{"id": "function_test_2507", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MADGIDRRNDDRLEFSTSKEVTVAPTFEDMHLKESLLRGIYAYGYESPSAVQSRAIVQICKGRDTIAQAQSGTGKTATFSISILQVIDTAVRETQALVLSPTRELATQIQSVIMALGDYMNVQCHACIGGTNIGEDIRKLDYGQHVVSGTPGRVADMIRRRHLRTRHIKMLVLDEADELLNRGFREQIYDVYRYLPPATQVVVVSATLPYDVLDMTTKFMTDPVRVLVKRDELTLEGIKQYFIAVEKEEWKFDTLCDLYDTLTITQAVIFCNTRRKVDWLTDKMREANFTVSSMHGEMPQKERDSIMQDFRQGNSRVLISTDVWARGIDVQQVSLVINYDLPTNRENYIHRIGRSGRFGRKGVAINFVTSDDVRILRDIELYYSTQIDEMPMNVADLLS", "output": "ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA (By similarity)."}]}
+{"id": "function_test_2508", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKLLSVCAVALLAAQAAGASIKHKLNGFTIMEHSDPAKRELLQKYVTWDEKSLFVNGERIMIFSGEVHPFRLPVPSLWLDVFQKIKALGFNCVSFYVDWALLEGKPGKYRAEGNFALEPFFDAAKQAGIYLLARPGPYINAEASGGGFPGWLQRVNGTLRTSDPAYLKATDNYIAHVAATVAKGQITNGGPVILYQPENEYSGACCNATFPDGDYMQYVIDQARNAGIVVPLINNDAWTGGHNAPGTGKGEVDIYGHDSYPLGFDCGHPSVWPKGNLPTTFRTDHLRESPTTPYSLIEFQAGSFDPWGGPGFAACAALVNHEFERVFYKNDLSFGAAILNLYMTFGGTNWGNLGHPGGYTSYDYGSPLTESRNVTREKYSELKLIGNFVKASPSYLLATPGNLTTSGYADTADLTVTPLLGNGTGSYFVVRHTDYTSQASTPYKLSLPTSAGRLTVPQLGGTLTLNGRDSKVHVVDYNVAGTNILYSTAEVFTWKKFGDSKVLVLYGGPGEHHELAVSLKSDVQVVEGSNSEFTSKKVEDVVVVAWDVSASRRIVQIGDLKIFLLDRNSAYNYWVPQLDKDDSSTGYSSEKTTASSIIVKAGYLVRTAYTKGSGLYLTADFNATTPVEVIGAPSNVRNLYINGEKTQFKTDKNGIWSTGVKYSAPKIKLPSMKDLDWKYLDTLPEVQSTYDDSAWPAADLDTTPNTLRPLTMPKSLHSSDYGFHTGYLIYRGHFVADGSETTFDVRTQGGSAFGSSVWLNEAFLGSWTGLNANADYNSTYRLPQVEKGKNYVLTVVIDTMGLNENWVVGTDEMKNPRGILSYKLSGRDASAITWKLTGNLGGEDYQDKIRGPLNEGGLYAERQGFHQPEPPSKKWKSASPLDGLSKPGIGFYTAQFDLDIPSGWDVPLYFNFGNSTKSAYRVQLYVNGYQYGKFVSNIGPQTSFPVPQGILNYQGTNWVALTLWALESDGAKLDDFELVNTTPVMTALSKIRPSKQPNYRQRKGAY", "output": "Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans."}]}
+{"id": "function_test_2509", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MHESRLASARLYLCTDARRERGDLAQFAEAALAGGVDIIQLRDKGSPGELRFGPLQARDELAACEILADAAHRYGALFAVNDRADIARAAGADVLHLGQRDLPVNVARQILAPDTLIGRSTHDPDQVAAAAAGDADYFCVGPCWPTPTKPGRAAPGLGLVRVAAELGGDDKPWFAIGGINAQRLPAVLDAGARRIVVVRAITSADDPRAAAEQLRSALTAAN", "output": "Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)."}]}
+{"id": "function_test_2510", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTGPEHGSASTIEILPVIGLPEFRPGDDLSAAVAAAAPWLRDGDVVVVTSKVVSKCEGRLVPAPEDPEQRDRLRRKLIEDEAVRVLARKDRTLITENRLGLVQAAAGVDGSNVGRSELALLPVDPDASAATLRAGLRERLGVTVAVVITDTMGRAWRNGQTDAAVGAAGLAVLRNYAGVRDPYGNELVVTEVAVADEIAAAADLVKGKLTATPVAVVRGFGVSDDGSTARQLLRPGANDLFWLGTAEALELGRQQAQLLRRSVRRFSTDPVPGDLVEAAVAEALTAPAPHHTRPTRFVWLQTPAIRARLLDRMKDKWRSDLTSDGLPADAIERRVARGQILYDAPEVVIPMLVPDGAHSYPDAARTDAEHTMFTVAVGAAVQALLVALAVRGLGSCWIGSTIFAADLVRDELDLPVDWEPLGAIAIGYADEPSGLRDPVPAADLLILK", "output": "Bifunctional enzyme that catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives, and the FMNH2-dependent reduction of dehydro-F420-0 to form F420-0."}]}
+{"id": "function_test_2511", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTYSYTEKKRIRKDFSKLPSVMEVPYLLSIQLDSFRDYLQMETAPEDRRETGLHAAFKSVFPIVSYSGNAALEYVSYRIGEPVFDVKECQLRGVTYAAPLRVKVRLIIYDKESSNKAIKDIKEQEVYMGEMPLMTENGTFVVNGTERVIVSQLHRSPGVFFDHDKGKTHSSGKLLYSARVIPYRGSWLDFEFDPKDAVFVRIDRRRKLPASILLRGLGYTSEQMLEMFFETSKFSLGAEVCKLELVPSRLRGDIATFDIKDNDGNVIVEEGRRITARHIKQLEKAGITELEVPTEYLYGRVLAKDMIDQSTGEVLVECNTELTEEVVTKILDAGVKDIETLYTNDLDCGPFMSDTLRIDPTRTPLEALVEIYRMMRPGEPPTKESAENLFNNLFFSEERYDLSAVGRMKLNRRLGREESTGEGTLTHDDIIDVLKTLIAIRNGQGQVDDIDNLGNRRVRCVGEMAENQFRVGLVRVERAVRERLSLAESEGLMPQDLINAKPVAAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLATYARSNSYGFLESPYRKVVDGVVTDEVVYLSAIEESNYVIAQASAATDEGKRLTDELVTVRHQNEFTVAPPEAVNFMDVSPRQVVSVAASLIPFLEHDDANRALMGANMQRQAVPTLKSQVPLVGTGVERTVAQDSGVCVTARRGGVIESVDAARIVVRVNNEETEAGDAGVDIYNLTKYTRSNQNTCINQRSIVRQGDVIARGDVLADGPSVDLGELALGQNMRIAFMPWNGYNFEDSILISEKVVQEDRLTTIHIQELTCVARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVGPGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSQRVPTGTRGTVIDVQVFTRDGIEKDARALSIEKEQLDKYRKDLKDEYRIVEGATFERLMAALKGQEVISGPGLKKGAKLEEAYLAELPRADWFKLRMKDEALNELLEKSEQGLEDRKKEHEARFDDKKGKLQQGDDLAPGVLKIVKVYLAIKRRIQPGDKMAGRHGNKGVISAVMPIEDMPYDEFGNTVDIVLNPLGVPSRMNVGQVLETHLGAAAKGLGERISRMLDEQRKVAELRKLLDEIYNHSDEVFKVDLDSLTDKEIFELCNNLRGGVPMATPVFDGAKEAEVKRMLELAGLDTTGQTKLYDGRTGDAFDRPVTVGYMYILKLNHLIDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGDHRMEPGMPESFNVLVKEIRSLGIDIELESE", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_2512", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPTFLHHALLACGFLTRLVPARVATADDMAAAVRWFPLAGLVVGGACWLPFALGLAASHPAIQAWLYVLINLWVTRGLHWDGVADLADAWGSSATGERFWDILKDSRIGAFGVMGLLLGFGGQYIGAHEIFISGRLGVLIAAPIVGRGACVILAALVPPGSRSTLGRLTCAGADRIAIGVAATCGILVLLLTTPVMTTVTTIAICGAIVTALAHLARREGGINGDFMGACIAGCEGAVLLAASMG", "output": "Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate."}]}
+{"id": "function_test_2513", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSEISLIMLAAGNSTRFNTKVKKQFLRLGNDPLWLYATKNLSSFYPFKKIVVTSSNISYMKKFTKNYEFIEGGDTRAESLKKALELIDSEFVMVSDVARVLVSKNLFDRLIENLDKADCITPALKVADTTLFDNEALQREKIKLIQTPQISKTKLLKKALDQNLEFTDDSTAIAAMGGKIWFVEGEENARKLTFKEDLKKLDLPTPSFEIFTGNGFDVHEFGENRPLLLAGVQIHPTMGLKAHSDGDVLAHSLTDAILGAAGLGDIGELYPDTDMKFKNANSMELLKQAYDKVREVGFELINIDICVMAQSPKLKDFKQAMQSNIAHTLDLDEFRINVKATTTEKLGFIGRKEGMAVLSSVNLKYFDWTRL", "output": "Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)."}]}
+{"id": "function_test_2514", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLQFDLLTTDPASHARRGRLTLRHGQVQTPIFMPVGTHGSVKGVLPRSLHEMGAQIILGNTFHLWLRPGLAVLQGFGGLHGFEKWNKPILTDSGGFQVWSLGALRTITEEGVHFASPVNGDKLFLSPEVSMQIQTTLDSDIVMQLDECTPYETRGQRTTERAACQSMQMSLRWAKRSQDEFQRLNNPNALFGIVQGGMYENLRAESLAALAAMDLPGYAIGGVSVGEPKDEMLRIMAHTPHRLPAHKPRYLMGVGTPEDLVEGVAQGVDMFDCVMPTRNARNGTLFTRFGDLKIRNARHKTDPQPLDGSCTCYTCAGPSGVAWDQGGRDGFSRAYLHHLERCGEMLGPMLSTVHNLHYYLNLMREIRQALDAGEFTQLRARLKADRARGV", "output": "Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)."}]}
+{"id": "function_test_2515", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAHWRTPSRIFLVGPMGAGKSTVGRELANLLGLEFIDSDAAIEARTGVSIPWIFDIEGEAGFRAREAAVIDELTGRDGVVVATGGGAVTTPANRDLLGARGVVVYLYTPVSVQLQRTRHDTNRPLLQSDDPEARLQSLLAERDPLYREVADVVVETTGGRARSVARRIVEALQGQPS", "output": "Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate."}]}
+{"id": "function_test_2516", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MATKFPAFNQGLAQDPTTRRIWYGIATAHDFESHDGMTEEKLYQKLFSTHFGHLAIIALWVAGNLFHIAWQGNFEQFVLDPTHVRPIAHAIWDPHFGSGITEAMTQAGADGPVNIAYSGLYHWWYTIGMRTNEQLFQASIFMSILACWTLFAGWLHLQPKFRPSLAWFKNNESRLNHHLAVLFGFSSIAWTGHLVHVAIPESRGIHVGWDNWLTVLPHPAGLTPFFTLNWGAYAQNPDSLEQVFGTAEGAGTAIFTFLGGLHPQSEALWLTDIAHHHIAIGTVFIIAGHMYRNTFGIGHSLKEITEAHNTRHPLDPHKGSFGINHDGLYETVTNSLHFQLGLALAALGVATSLVAQHMGALPSYAFIARDYTTQSALYTHHQYIAMFLMVGAFAHGAIFFVRDYDPELNKDNVLARVLGTKEALISHLSWVTMILGFHTLGIYVHNDVVVAFGNPEKQILIEPVFAQFVQAAQGKMMYGFNALLSDPTSAASVAANSLPGNHYWMDLINRQDALSAFLPIGPADFLVHHAIALGLHTTALILIKGALDARGTKLIPDKKDLGYAFPCDGPGRGGTCDSSSWDAMYLAMFWALNLIAWVTFYWHWKHLAIWQGNVAQFNESGTYLMGWFRDYLWLNSAQLINGYNPFGVNSLSVWAWMFLFGHLVWATGFMFLISWRGYWQELIETLVWAHQRTPIANLVGWRDKPVALSIVQARLVGLAHFTIGNILTFGAFVIASTSGKFG", "output": "PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin/cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6."}]}
+{"id": "function_test_2517", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKAQILREMKVLTAIEPEFEVQRRVAFIKTKLKEARSKALVLGISGGVDSSTAGRLCQLAVDSLNHENSQGGYQFIAVRLPYQIQKDEHEAQLACQFIQPSKLVTVNVHQGVDGVHSATVAALAEAGLPLPDVAKVDFVKGNVKARMRMIAQYELAGLVGGLVVGTDHSAENITGFYTKWGDGACDLAPLFGLNKRQVRQLAAYLGAPESLVHKAPTADLEDNKPLLEDEVALGLTYAQIDDFLEGKDVGKAVEDKLIGIYKATQHKRQPIPTIYD", "output": "Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source."}]}
+{"id": "function_test_2518", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSSSFGKIFRVSTFGESHGGAVGVILDGCPPKLKIDINLIQNELDRRRPGQSDITTPRNEEDKIEILSGIKEGLTLGTPIAMLVRNKDQRPADYNNMEQVFRPSHADGTYHLKYGIQASSGGGRASARETIGRVAAGAVAKQLLKTFCNTEILSWVKRIHDIDSDINKEKISLKKIDSNIVRCPDEKVSTEMIERIKELKRQGDSCGGVIECLVRNVPSGLGMPVFDKLEADLAKALMSLPATKGFEIGSGFSGTYLKGSEHNDSFIKSDDSSKLRTTSNNSGGIQGGISNGENIEMKIAFKPTATIGKEQKTVNAEGKEVLMKAKGRHDPCVLPRAVPMVDAMVALVLADHLLLNHAQCDLINN", "output": "Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system."}]}
+{"id": "function_test_2519", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKTWVIKIGTSILRGTEETSTEEVIENLSRSFTSFLSKGNKLILVTSGAVGLGCQKLNIKTRPNDLSTLQATAAVGQVNLMSLYDKVFNKLGLNIAQILITKADFNSRESFNNASKTLKRLIDLNVIPIVNENDTVANEELKYGDNDTLSALVALAINANKLILLTDIENLYSKDPRNNKDAQPIKEVHNSELKEIKDKNIQNSNNEWGTGGISTKLISAEIATKGGVEVQLVDGTNKKNLIEIFNDNKIGTLFYPVEKPIGNKKSWLSHAIQTVGKITLDDGASFAIKKKGASLLAVGVKNVEGNFTINQAVKIVNTNDKEVAKGLVSISSDKLRSILNNKENNNSSIIVVHRDVLALS", "output": "Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate."}]}
+{"id": "function_test_2520", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSEKRPLILLPAVDVVEGRAVRLVQGKAGSETEYGSALDAALGWQRDGAEWIHLVDLDAAFGRGSNRELLADVVGRLDVAVELSGGIRDDESLEAALATGCARVNIGTAALENPQWCAKVVAEFGDKVAVGLDVKIVDDQHRLRGRGWETDGGDLWEVLDRLDSEGCSRYVVTDVTKDGTLQGPNLDLLGRVADRTDAPVIASGGVSSLDDLRAIATLTDRGVEGAIVGKALYAGRFTLPEALAAMGQ", "output": "Involved in both the histidine and tryptophan biosynthetic pathways."}]}
+{"id": "function_test_2521", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MQLLAVGLNHTTAPVSLREKVAFPADQLGQAVASARVWYGRSDSKTYSDEAAILSTCNRTELYAASHQPGGVNEAIDLTAHFLADYHKLPYSELRPYLYALPQDNAVRHAFRVASGLDSMVLGEPQILGQMKDAVRQAEAAGGLGTYLHQMFQRTFAVAKEVRSNTEIGAHSVSMAAASVRLSQRIFDTISEQNVLFIGAGEMIELCATHFAAQNPKSLTIANRTLERGETLAHRFNGRAIRLADLPDQLASYDIVISSTASSLPIIGLGMVERAIKARRHKPMFMVDLAVPRDIETEIGRLDDVFLYTVDDLGTFVQTGLENRQAAVTQAEAIIETRVQSFMHWIDARAVVPVIQDLHESSEMMRMIELERARKLLAKGEDIDAVLEALSKGLTAKFLHGPQQALNNAQGDERTRLAALLPQLFRTKR", "output": "Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA)."}]}
+{"id": "function_test_2522", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDLEALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRRFVQNALNGNGDPNNMDKAVKLYRKIKREITFHGAKEIALSYSAGALASCMGLIYNRMGAVTTEVAFGLVCATCEQIADSQHRSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGSSERAAEAMEVASQARQMVQAMRTIGTHPSSSAGLKDDLLENLQAYQKRMGVQMQRFK", "output": "Plays critical roles in virus replication, from virus entry and uncoating to assembly and budding of the virus particle. M1 binding to ribonucleocapsids (RNPs) in nucleus seems to inhibit viral transcription. Interaction of viral NEP with M1-RNP is thought to promote nuclear export of the complex, which is targeted to the virion assembly site at the apical plasma membrane in polarized epithelial cells. Interactions with NA and HA may bring M1, a non-raft-associated protein, into lipid rafts. Forms a continuous shell on the inner side of the lipid bilayer in virion, where it binds the RNP. During virus entry into cell, the M2 ion channel acidifies the internal virion core, inducing M1 dissociation from the RNP. M1-free RNPs are transported to the nucleus, where viral transcription and replication can take place.; "}]}
+{"id": "function_test_2523", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFKKTKITILGATGSIGDSTLAVIRETNDFEVFALTAFSNVEKLAELCQEFKPKFAVVPDLSKKQKLQSLVTDVEVLVGESGLEKVSSLAEIDIVMSAIVGIAGLKPTFAAAKAGKKILLANKESLVTAGHLLIDEVVKNNAQLIPVDSEHNAIFQCIDNHDKKCLPEIDKIILTASGGPFRDKQLHELTDVTPEQACNHPNWQMGRKISVDSSTMVNKALEVIEAYWLFSVSADKIGVLIHPQSVTHSMVRYVDGSYIAQLGVPDMKTPIANAMYYPKRGSVNVESLDFTKYQLTFREACFERFEALKIVFNNLQNKNYAANIVFNAANEELVAAFLNKKIKYLEIIEVNKKVTKELNFENPKNIEEVFEIDRKTREYVDSVLG", "output": "Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)."}]}
+{"id": "function_test_2524", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MILIDGKSLSKDLKERLATQVQEYKHHTAITPKLVAIIVGNDPASKTYVASKEKACAQVGIDSQVITLPEHTTESELLELIDQLNNDSSVHAILVQLPLPAHINKNNVIYSIKPEKDVDGFHPTNVGRLQLRDKKCLESCTPKGIMTMLREYGIKTEGAYAVVVGASNVVGKPVSQLLLNAKATVTTCHRFTTDLKSHTTKADILIVAVGKPNFITADMVKEGAVVIDVGINHVDGKIVGDVDFAAVKDKVAAITPVPGGVGPMTITELLYNTFQCAQELNR", "output": "Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate."}]}
+{"id": "function_test_2525", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTTAAIRGLQGEAPTKNKELLNWIADAVELFQPEAVVFVDGSQAEWDRMAEDLVEAGTLIKLNEEKRPNSYLARSNPSDVARVESRTFICSEKEEDAGPTNNWAPPQAMKDEMSKHYAGSMKGRTMYVVPFCMGPISDPDPKLGVQLTDSEYVVMSMRIMTRMGIEALDKIGANGSFVKCLHSVGAPLEPGQEDVAWPCNDTKYITQFPETKEIWSYGSGYGGNAILAKKCYALRIASVMAREEGWMAEHMLILKLINPEGKAYHIAAAFPSACGKTNLAMITPTIPGWTAQVVGDDIAWLKLREDGLYAVNPENGFFGVAPGTNYASNPIAMKTMEPGNTLFTNVALTDDGDIWWEGMDGDAPAHLIDWKGNDWTPESDENAAHPNSRYCVAIDQSPAAAPEFNDWEGVKIDAILFGGRRADTVPLVTQTYDWEHGTMVGALLASGQTAASAEAKVGTLRHDPMAMLPFIGYNAGEYLQNWIDMGNKGGDKMPSIFLVNWFRRGEDGRFLWPGFGDNSRVLKWVIDRIEGRVGADETVVGHTAKAEDLDLDGLDTPIEDVKEALTAPAEQWANDVQDNAEYLTFLGPRVPAEVHSQFDALKARISAAHA", "output": "Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle."}]}
+{"id": "function_test_2526", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRINPTTSDPGVSILENKNLGRIAQIIGPVLDVAFPPGKMPNIYNALVVKGRDTLGQEINVTCEVQQLLGNNRVRAVAMSATEGLKRGMDVVDMGTPLSVPVGGATLGRIFNVLGEPVDNLGPVDTRTTSPIHKSAPAFIQLDTKLSIFETGIKVVDLLAPYRRGGKIGLFGGAGVGKTVLIMELINNIAKAHGGVSVFGGVGERTREGNDLYMEMKESGVINEQNLAESKVALVYGQMNEPPGARMRVGLTALTMAEYFRDVNEQDVLLFIDNIFRFVQAGSEVSALLGRMPSAVGYQPTLSTEMGSLQERITSTKKGSITSIQAVYVPADDLTDPAPATTFAHLDATTVLSRGLAAKGIYPAVDPLDSTSTMLQPRIVGEEHYETAQQVKQTLQRYKELQDIIAILGLDELSEEDRLTVARARKIERFLSQPFFVAEVFTGSPGKYVGLAETIRGFKLILSGELDSLPEQAFYLVGNIDEATAKATNL", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits."}]}
+{"id": "function_test_2527", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPVQHCLTYLFARHHGGTFLIRIEDTDRKRHVEDGERSQLENLRWLGIDWDESPETHENYRQSERLDIYQKYVDQLLAEGKAYKSYVTEEELAAERERQEAAGETPRYINEYLGMSEDEKTAYIAEREAAGIVPTVRLAVNEAGIYKWNDIVKGEIEFEGGNIGGDWVIQKRDGYPTYNFAVVIDDYLIKISHVIRGDDHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRRKGYMPEAVFNFIGLLGWNPGGEEEIFSREQFIQLFDENRLSKSPAAFDQKKMDWMSNEYIKNADLETIFNLAKPFLEEAGRLTDKAEKLVELYKPQMSSADEIVGLTDLFFSDFPELTAEEKEVMAGETVPTVLNALKEKLEAMTDEDFQPDNIFPQIKAVQKETGIKGKNLFMPIRIAVSGEMHGPELPNTIYLLGREKSIQHIDNMLKSL", "output": "Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)."}]}
+{"id": "function_test_2528", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQPQRVVITPGEPAGIGPELVVQLAQRSWPVELVVCADATLLQDRANMLGLPLRLLPYRADQPPVPQQQGTLTLLPVVLRKPATPGVLSTDNGHYVVDTLARACDGCLNGEFAALITGPVHKGVINEAGVPFTGHTEFFEERSHSDNVVMMLATEELRVALATTHLPLKAISDAITPALLREIITILHHDLRTKFGIADPHVLVCGLNPHAGEGGHMGTEEIDTIIPVLNEMRAKGMNLSGPLPADTLFQPKYLDSADAVLAMYHDQGLPVLKYQGFGRAVNITLGLPFIRTSVDHGTALDLAGKGKADVGSFITALNLAIKMIVNTQ", "output": "Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)."}]}
+{"id": "function_test_2529", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIEFVYPHTHLVAGVDEVGRGPLVGAVVTAAVILDPARPIVGLNDSKKLSEKRRLALFDEIKEKALAWSLGRAEPEEIDELNILHATMLAMQRAVAGLKIVPEYVLIDGNRCPALPMRSLAVVKGDSRVAEISAASIIAKVTRDAEMAALDLSYPQYGFAQHKGYPTAFHLEKLSEHGPTEHHRRSFGPVKRALGLVC", "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."}]}
+{"id": "function_test_2530", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAQHDENVVWHPHPVTVAQREQLHGHRGVVLWFTGLSGSGKSTVAGALEEALYQQGVSTYLLDGDNVRHGLCSDLGFSDDDRKENIRRVGEVASLMADAGLVVLTAFISPHRAERQMVRERVGHDRFIEVFVDTPLAICETRDPKGLYKKARAGELKNFTGIDAVYEAPESPQIHLDGQQLVTNLVSQLLDLLRQDDIIRS", "output": "Catalyzes the synthesis of activated sulfate."}]}
+{"id": "function_test_2531", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLNFLQSVQFAKEIEKKIIEYEQDIDISEATMLYEIAKHDFDLVKNLADTIKRYYFKNNIELCSIYPAKVGMCTEDCKFCSQSIYHSCKIEIKDVASVDEVIEYLENIIAFPVKRFSLVTSGGELNDSEFERIIDIISYISKNYDIHLCASLGFLTKERAKKLMLAGVTRYHNNLETSSTYFKNICSTHTQAQKIETLKIAKETGLEICSGGIISMGEDMIERIKLAFELRELKVDSVPINILNPIKGTPFEDMKIMDQNEIFITLALFRIVLPRKTILLAGGKENALKDMEKIAYKCGINGCMVGNYLTTQGMGIKEKVEMLESLGLEV", "output": "Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism."}]}
+{"id": "function_test_2532", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQFKQDFFTQLPEFYSQVYPQGLSHPQWLAWSHDAAQLIGLTQPTDELLLGLSGNAAIDGATYYAQVYSGHQFGGYTPRLGDGRSIILGEAIGPNGAWDVALKGGGPTPYSRHGDGRAVMRSAVREFLVSEALYHLHVPTTRALAVIGSDMPVWRESQETAAITVRLARSHIRFGHFEFFCHSERGRADKLLQLLNFTITQHYPHLSCDPSGYKAWFLQVVQDTAKMIAHWQAVGFAHGVMNTDNMSILGDSFDFGPFAFLDTFQEDFICNHSDPEGRYAFGQQPGVGLWNLQRLAQALTPVIPSDDLIAILNQYQEALVQTYLLLMRAKLGLTTLDKSTAEQDKQDLELIGQFTVLMEKNQLDYAQTWRQFGQLDPRSQHSSLRDDFIDTHQFDTWYKAYQLRLGDVTDIAAWQTERNSVNPKYILRNYLAQEAIIAVEEGNLAPLQRLQQVLSQPFAEQVEHDELAKRPPDWGQGLIMSCSS", "output": "Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation)."}]}
+{"id": "function_test_2533", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQTADIRNAWLTYFGDRGHTVVPSASLVSDDPTLLFTVAGMVPFVPYLTGVVPAPFPRATSVQKCIRTLDIEEVGRTPRHGTFFQMNGNFSFGDYFKEQAIAYAWELLTTSEADGGLGFSPDDLWVTVYHEDDEARQAWKRIAGLPDERIQGLGRDTNYWHTGQPGPAGPCSEIFFDRGPAYGADGGPATDDDRYVEIWNLVFMQYLRGAGTGKSDFEILGDLPKKNIDTGMGLERVAFLKQGVENMYEIDQVRPVLDRAAELSGRRYGADHEDDVRMRIVADHVRSSLMLMSDGVRPSNEGRGYILRRLMRRTVRAMRLMGVDAATFGELFPASRDAMKAAYPEVSDDFDRISRLAYAEEETFLRTLSGGTTILDVAVGETKAKGGERIAGDTAFLLHDTFGFPIDLTLEMAEENGLTVDREAFDRLMLEQRTRAKADAKSKKTALADLTVYSEFRAAGETRFTGYDELETGTTILGLIVGGRSVDHAVAGDIAEVILPETSLYAESGGQEADAGSIVGQGFDLEVLDVQKPVKGLISHRVQVRSGEVGVGDAATTVVDADWRRGATQAHSGTHLVHAALRQVLGQDAHQSGSYNRAGYMRLDFAWNQALSSETRSEIEDIANGAVRDDLRVVTRVMPIDEAKQLGAMALFGEKYGDTVRVVDIGGPWSRELCAGTHVSSSAQIGLINVVGESSVGSTNRRIESLVGREAFQDLAVERAIVSQLTSTLKTPREQLPDRIADLMQNLKTAERRIADFEAQALQQRVPALLAQGSRVGAVTLIQESLGAVRSADEVRQLVTLVRERAGSEPVVVALAGDAGGKPTVIVATNQAARDAGAKAGQLARAAAAVLGGGGGGKDDLAQGGGSDVSAIGDALTAVRQALAS", "output": "Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain."}]}
+{"id": "function_test_2534", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPIQINKTVIFLMGPTASGKTNLAIKLSQQFKTRLISVDSALIYKGMNIGTAKPDKATLKKYPHYLINICSPESSYSVFDFIRDANKQIKTAFAKNELPILVGGTSFYFHVLEHGLSNLPESSTKSKEKFNQLLRNKGTIKLHQDLKKIDPQAANKIHPNDSQRIIRALEVFNLSGKTISELQGNKKPIIDYPIKKIILMPKRNELHTKIETRFLLMMKNGFLNEVQHLKQNPNLHQNLSSIRCVGYRQAWQYLNGKIDKTEMIEKIIIATRQLCKRQITWLKSEKYALVLNNSNLAKAVTFINS", "output": "Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)."}]}
+{"id": "function_test_2535", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSAKDIKFGPEARNLMLDGVNMLANAVKVTLGPKGRNVVLDKSFGGPTITKDGVSVAQEITLEGKFENMGAQMVKEVASKTNDIAGDGTTTATVLAQALVTEGVKSVAAGMNPMDLKRGIDKATEVAVNALHDFSQPCNDTKAIAQVGTISANSDVSVGDIIADAMEKVGQAGVITVEEGSGFENELDVVEGMQFDRGYLSPYFVNNQDTMTADLESPFVLLHDAKISNIRDLLPALEIVQKSSKALLIIAEDIDGEALATLVVNNMRGIVKVAAVKAPGFGDRRKAILEDIAILTGSVVISEEVGLSLEKVTEEHLGTAKRIEIGKENTVIVDGAGKKSNIDGRVNQIKAQIETTTSDYDKEKLLERLAKLSGGVAVIKVGAATEVAMKEKKDHVDDALHATRAAVEEGVVPGGGVALVRTIKALDGLTGDNHDQNIGIDIAKRAMEAPLRQIVTNGGGEASVVLNNVADGKDNYGYNATTEEYGDMLKMGILDPTKVVRAALQHAASISGLMITTEAMITDIPQDATPTASPDMGGMGGMGGGMM", "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."}]}
+{"id": "function_test_2536", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPIRARIIGIDPGLRFTGFGIIEADGNRLRHVADGVIATDGAAAVAERLHTLDAALARLLATYAPDHAAVEETYVNRNATATLKLGYARGVALLAPARAGIAVAEYGAKTVKRAVVGTGAAEKDQVALMVRRLLPGAAITRADAADALAVAICHAHHLATASRVPAA", "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."}]}
+{"id": "function_test_2537", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MFNLLDNYKDVNDIKKMSLDEKKQLALEIREFLIENVSKTGGHLASNLGVVELTLSLFSIFDLNHDKLIWDVGHQAYVHKLLTGRKDKFHTLRQFGGISGFPKKCESVYDFFETGHSSTSISAALGMARARDLKGEKHNVVAVIGDGALTGGMALEALNDVGYRKTKLIIILNDNQMSIGKNVGGVSRYLNKLRVDPKYNKFKEEVESTLKKIPNIGKGMAKYLERLKNGIKKMVVSGMFFEDIGIKYLGPIDGHNIKDLTEVMTAAKKVNNPVIIHVITKKGKGYEFAEKNPGKFHGIGPFNCNNGEIAATSTNTYSKVFGDEMVNLAREDKKIVVITAAMRDGTGLQNFAKEFPERFFDVGIAEQHAVTLAGGMAVEGLKPVFAVYSTFLQRSYDQLLHDICIQKLPVVFAVDRAGIVGDDGETHQGIFDLSYLTEMPNMTVMSPKCMAELTHMLKWALNQNCPIAIRYPRGGDNVYLTPLEDFEFGRWEYILNKGKIALVAQGRMVEHAVLAAEKLEQMGILVRVISACFIKPLDKVMLKKLIEEDVTIITIEDNIIRGGLGSYILEYVNTLHRKVDVINLGFKDEFVRHGKPSILYKLYGLDTGSIVDKVLKVVKLSGIF", "output": "Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)."}]}
+{"id": "function_test_2538", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLLTIDIGNTNIKIGVYQDERLTAHWRVTTERHRLADEYLVLLHNLFDLGGIDPREIDGCAISCVVPPLTGEFRTLCRTYFRVEPLMVNATTPTGLRYNVDTPAELGADRIANSLAAFRRYGGPVIVLAFGTATTFDVITADGEYIGGAIAPGIGISADALFRLAAKLYQVELVRPPSVIGKNTIHHMQSGVILGYAGLVEGLVNRMQAELGTSCPVVATGGLAELIAAETEAITTVEPYLTLEGLRLIYEMNRS", "output": "Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis."}]}
+{"id": "function_test_2539", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLAKRIIPCLDIKDGQTVKGTNFVNLRQAGDPVELGRTYSEQGADELVFLDITASHEGRKTFTDLVKRVAANINIPFTVGGGINELSDVDRLLNAGADKVSINSSAIRNPDLVDKIAKHFGSQVCVVAIDAKQTETGWKCYLNGGRIETDKYLFDWAKEVNNRGAGEILFTSMNHDGVKNGYANEALSTLADLLTIPVIASGGAGCMEHFRDTFAKGKADAALAASVFHFGEIKIPELKQYLCEQGINVRL", "output": "IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit."}]}
+{"id": "function_test_2540", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSKKALLIICDGWGIGDKGKDDVIFNTPTPYWDELLKTYPASQLQASGENVGLPDGQMGNSEVGHLNIGAGRIVYQDLVKINIACRENTIMENPEIKRAYSYAKENNKQIHFMGLVSDGGVHSSLEHLLKLTDIAKEYGISKAYVHCFMDGRDTDPKSGKGFIEELENHLKTTGGKIASIIGRYYAMDRDKRWERVKEAYDLLVEGKGKQAECMVKAMEESYAEGVTDEFIKPIVHVENGKPVAVIEEGDVVIFFNYRNDRAKELTVVLTQQDMPEAGMHTIPGLQYFCMTPYDASFKGVHILFDKENVNNTLGEFLANVGKTQLHIAETEKYAHVTFFFNGGRETPFDSEERILVPSPKVATYDLKPEMSAFEVKDKLVDAINTKKFDFIVVNYANGDMVGHTGIYKAIEKAVVTIDACLHDTVEAAKANDYEVIIIADHGNADHALNEDGTPNTAHSLNPVPFVYVTANKDAKVEDGILADVAPSILHILGLKQPKEMTGKSLIK", "output": "Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate."}]}
+{"id": "function_test_2541", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGFSEARAYRAFGGRSTWLTVFLALANSLAVSAKCAADYFVDSLPGQPDSPQVQMHAGHIEINHKTSANLFFWHVANQHIADKPRTVIWLNGGPGCSSEDGALMEIGPYRVTNDHLLNHTDGSWDEFANLLFVDQPVGTGFSYVSTGAYVSELGEMASQFVTFLEKWFELFPHYEKNDLYFAGESYAGQYIPYIARAILDRNKKGESLTRWKLKGILIGNGWISPRHQYLSYLPYAYQEGIIQGGTDSSSRVEAKLSKCLNKLNVEDSTGTVQISACEEVLQAIIDETHKGNRCINMYDIRLTDEYSACGMNWPPDLENMAPYLRFKNVTKALHINSDKQTGWSECSGAVSGHFRALKSKPSVELLPGLLEEGLPILLFSGQKDMICNHIGNEDLIKDMKWSGGTGFELSPGVWAPRQDWIFEGESAGFYQQARNLTYVLFYNASHMVPFNYPPRSREMLDRFIGVDIADIGGNPADSRIDGEKGPATSVRAHPNSTAAAEREKEKVKSAMWKAYYKSGEVALIVVAIAAVIWGVFIWRSRQKHQDRGYEFRGIYPMLGSSSSGSLPRYSNKRGRRGHDVEAVNIYEAELDERPSRVVSARSSREQEPYVVGDEDGSDVDDDTSDERKRLVDKP", "output": "Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity)."}]}
+{"id": "function_test_2542", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPLITVGINHKTAPVSIRERVAFAPEKMIDALSSLISENKANEAVIVSTCNRTELYCSVEDLSKVDDVIAWLGKYHGIALPELQQYCYTHADDDSVRHVMRVASGLDSLILGEPQILGQVKSAYAVSQEGSCIGPELESLFQRTFSVAKRVRTDTAIGENPVSIAFAAVSLAQRIFADIRNSTALLIGAGQTIELVARHLKENGIKHIIVANRTLARAQILADELNAEAIMLGDIGDYLSQADIVISSTASQLPIIGKGMVERATSQRRHSPMLLIDIAVPRDIEPEVEEVNDAYLYTVDDLHSVIEENVRARQDAAKAAEQMIEEGVDSYRRVVESRKVSDLIVTFRQSAEAIKNTELEKALKGLEMGQSPEQVLNKLAHGLMNKLIHAPTRYLRDAGADADQDALIIASNVLGIYEEKDN", "output": "Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA)."}]}
+{"id": "function_test_2543", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSIKYVATSKLPTPWGVFAMHGFEDTESGKEHVALTFGTLSADEPVLGRIHSECLTGDALFSLRCDCGFQLQAAMQNIAETGSGFILYLRQEGRGIGLLNKIRAYELQDKGANTVEANEQLGFEADMRKYDMIKPMLEQIGVKHVRLMTNNPRKVKAMKEFGIEVVERVPLQVGKNRYNEAYLKTKSTELGHMMSEYHFMDENK", "output": "Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate."}]}
+{"id": "function_test_2544", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIPRTRTLLQSKIPITRYFARCWAPRVRYNVCRTLPAAALHTNIIAHNEVKKDDKKVHLGSFKVDKPKMMIAFTCKKCNTRSSHTMSKQAYEKGTVLISCPHCKVRHLIADHLKIFHDHHVTVEQLMKANGEQVSQDVGDLEFEDIPDSLKDVLGKYAKNNSENASQLPHPSQK", "output": "Involved in protein import into mitochondria. Acts as a Hsp70-specific chaperone that prevents self-aggregation of the matrix Hsp70 chaperones SSC1 (mtHSP70) and SSQ1, thereby maintaining their function in mitochondrial protein import and Fe/S protein biosynthesis. May act together with PAM18 as co-chaperone to facilitate recognition and folding of imported proteins by SSC1 in the mitochondrial matrix (By similarity)."}]}
+{"id": "function_test_2545", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSDTASWQPSAPIANLLKRAAIMAEIRRFFADRGVLEVETPTMSQATVTDIHLVPFETRFVGPGAADGLTLYMMTSPEYHMKRLLAAGSGPIYQLGRSFRNEEAGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQILDCNSAETLSYQQAFLRHLNIDPLSAEKAQLREVAAKLDLSNIADTEEDRDTLLQLLFTVGVEPYIGRDKPAFIYHFPASQASLAEISTEDHRVAERFEVYFKGIELANGFRELTDGDEQLQRFEQDNRNRAKRGLPQNPIDMNLIAALKQGLPDCSGVALGVDRLVMLALNAERLSDVIAFPVNIA", "output": "With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P."}]}
+{"id": "function_test_2546", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKRFKRAGAIIETLKEHGHEAYFVGGSVRDFIIDRPIGDIDIATSALPEEVMKLFPKHVPVGLEHGTVIVLQDGEPYEVTTFRTESDYEDFRRPSSVQFVRSLEEDLKRRDFTMNAIAMNEDGEIIDLFGGQEAIQKREIVTVGNAAERFQEDALRMMRGIRFVSTLGFSLEEKTECAIKRYGHLLEHIAIERITVEFEKLLTGPYCVKGLQKLVETKLFMHLPYLQMSEEKILKAAEYNWESFETEIEAWAFFLSCIGEEHPSVFLRQWKFSNKKIKEIVAVLLAIRTRKTKEWDAVFLYQTGVQIALMAERVYQVMIEEYNMSTVSEVQRLFDSLPIQKRQEMNVSGNDLLSWTDKTPGPWVAEVLQKIEEEILQKRLENEKEAIRGWIEECNLL", "output": "Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate."}]}
+{"id": "function_test_2547", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKKAVVVFSGGQDSTTCLVQALKEFDEVHAITFDYGQRHKLEIEVAEKVAKDLGVAAHKVMDVGLLNELAISSLTRDDIPVSHELQENGLPNSFVPGRNILFLTLAGIYAYQIGAETVITGVCETDFSGYPDCRDDFVKAMNSALVKGMDRQFEIKTPLMWLNKAETWALADQYDALQLVRESTLTCYNGIIGDGCGDCPSCDLRKAGLDDYLNNKDAVMQSLIQKQKSEDQ", "output": "Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))."}]}
+{"id": "function_test_2548", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEKRPEDTRVVVGMSGGVDSSVAALLLKEQGYDVIGIFMKNWDDTDENGFCTATEDYEDVIRVCNQIGIPYYAVNFEKQYWEKVFQYFLDEYKAGRTPNPDVMCNKEIKFKAFLDHALSLGADYLATGHYARVDRSAGTVRMLRGLDENKDQTYFLNQLNQEQLSKVMFPIGDLQKSRVREIAKEAELATAAKKDSTGICFIGERNFKTFLSQYLPAQPGDMMTMDGEVKGRHDGLMYYTIGQRHGLGIGGSGEPWFAVGKDLEKNILYVDQGFHNPLLYSDKITATNVSWTRPGLMDGGEMTCTAKFRYRQEDHKVTVKMTGDDEAEVIFDGQVRAVTPGQAVVFYDGEECLGGGTIDDVYKDGTKLWYV", "output": "Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34."}]}
+{"id": "function_test_2549", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIRIAIDAMGGDFGAEPIISGVIEALKEAEFKAVLVGDSNAIKPLIPQPYLKNIEFIEATEVISMSDGATDALKRKDSTIYKAVELLKEKEVDAVVSAGHSGATMSLATLRVGRLKNVSRPAIATLMPNSKETATLVLDVGANVDCRSEHLFQFAIMGEAYAKEILGRKEPKVGLLSNGEEESKGNEVSKEAFKLVSRLDSFVGNAEGNQIFDGSIDVMVCDGFMGNILLKTSEGVADAIGKIIKKQVKKSPLAMAGSVLMRKVFKTLKKQVSYDEYGGAPLLGVNGCVIISHGKSNSKAIKNAIFQAIKFANSNINKVIEEELSHFAR", "output": "Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA."}]}
+{"id": "function_test_2550", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFAEAEGLLGSNENVDAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMALAQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDALQGKVEKNCVNPHVAD", "output": "Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively."}]}
+{"id": "function_test_2551", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRTQWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTISIELRDDGDIRLLTPVEGVEHEDNLIVRAARLLMKTAADSGRLPTGSGADISIDKRLPMGGGLGGGSSNAATVLVALNHLWQCGLSMDELAEMGLTLGADVPVFVRGHAAFAEGVGEILTPVDPPEKWYLVAHPGVSIPTPVIFKDPELPRNTPKRSIETLLKCEFSNDCEVIARKRFREVDAVLSWLLEYAPSRLTGTGACVFAEFDTESEARQVLEQAPEWLNGFVAKGVNLSPLHRAML", "output": "Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol."}]}
+{"id": "function_test_2552", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAKQLSFSNESREALEKGVNFVANAVKVTIGPKAKNVVIDRKFGSPDIVSDGSTVAKEIEIENPISNLGAKLIEQVASKTKESAGDGTTTATILTQKMVQEGLKNIASGASPIELKKGMEVGLDFVLEKLSSKSISLSGSDIQKVATVSAGGDEEIGSIISKAMDIVTSDGVINVEESQSLDTELDITEGMSFDRGYSSPYFVTDQERQICELENPKILITDQKISTLVDLVPILEEIQKSGSPFLILAEDIEGEALTTLVLNKNSGVLNVASVRAPLFGERRKAALEDIAILTGAKLISEDKSMTLDKVSINDLGKAKKITITKDKTTIIAFEDTKDLVKARVEKLKREVDMTDSEYDQDKINERIAKLAGGVALIKVGAATETEMKYKKLRIEDSLNATKAAIEEGVVPGGGQTLIEISDDLLNLSQTSSDDLRTGINIIKEALLEPTKQIAKNAGFNGDVVIAEIKRLNKGFNANSGKYEDLKNSGILDPTKVIRLALQDSVSIAAMLLTTEVAIADIPEPEPAAPGGPSGDPMGGMGGMGMPGMGGMGMPGMGGMGMPGMGGMGMPGMGGMGMPGMM", "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."}]}
+{"id": "function_test_2553", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDVRGTAIRSDAGLFGYERALVRRGLGPVAGVDEAGRGACAGPMVVAAVVLDQRRLGLLRRLADSKLLTERVREEVHADVLAAAAAVSTIVIPAAEIDRNGVHVANIMGMRRAVAVLDVRPRYVLTDGFAVAGLGAESLAVIKGDLMVGCIAAASVVAKVTRDRIMRSLHKRYPEYDFAQHKGYVTAAHTAAMTRYGPCEQHRLSYVNVAALAAPAGETRSLRLEDRVAMTSLRGVTETA", "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."}]}
+{"id": "function_test_2554", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSLFDWFAARRKDQFVGKVIQEAEEADGLWGKCPECSQVVYRKDLLENANVCSNCGHHNRINSDERIKLIADQNSFKSTDKHLSPVDPLGFKDRRAYADRLRESQSSTGMKDGVTTGVCQVEQIPLALAVMDFRFMGGSMGSVVGEKITRLIEKATNQKLPLLIVCASGGARMQEGMLSLMQMAKISGALERHREAELLYMPLLTHPTTGGVTASFAMLGDLILAEPKALIGFAGRRVIEQTLREKLPDNFQTAEYLLDHGFVDKIIPRTQLKKTLGVLLRLHGYREKRK", "output": "Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA."}]}
+{"id": "function_test_2555", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNTNIGIIDYGMGNLHSVQQSFKRLDQSIRIVKSPNDVHECNALILPGVGSFDPAMENLRRTDLIPKIKSWVKDGKPLLGICLGLQLIFESSEEGNSEGLGLLKGKVCNLPRNTKERIPHMGWSLLKQIKECPLLDNENTSRWMYFVHSYSAIPSPEDLAATVSFGDSEVTAIVWKDSLGACQFHPEKSGKSGQRLLSSWLKWLHEKNSDLS", "output": "IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF."}]}
+{"id": "function_test_2556", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTHSKRWLEEHEKDPYVKRAKKEGYPSRAAYKLLEIHQKYKLFKPSMNVIDLGAAPGGWSQVAKDLVGPKGVVIAIDLLPMQSMLDVIFIQGDFNEPEIFNQLEAIVAKKTLTGQVDLVISDMAPNISGIKNVDQSRSLHLVELAWDCAQKLLARGGTFLVKVFQGPGVDRFLINLRPYFNQVKFLKPSASRSRSSEIYILAGEFLGYNQRV", "output": "Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit."}]}
+{"id": "function_test_2557", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGRGRIIACDLLPMDPIVGVDFLQGDFRDELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGSFVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRK", "output": "Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit."}]}
+{"id": "function_test_2558", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTVLIHVLGSDIPHHNHTVLRFFNDTLAATSEHAREFMVAGEDNGFTESCPALSLRFYGSKKALAQAVIAKAKANRRQRFFFHGQFNTSLWLALLSGGIKPAQFYWHIWGADLYEVSHGLKFRLFYPLRRIAQGRVGGVFATRGDLSYFARQHPGVRGELLYFPTRMDPSLNAMAKERQRAGKLTILVGNSGDRSNQHIAALRAVYQQFGDTVNVVVPMGYPANNQAYIDEVRQAGLALFSAENLQILSEKMEFDTYLALLRQCDLGYFIFARQQGIGTLCLLIQADIPCVLNRDNPFWQDMAEQHLPVLFTTDDLNEQVVREAQRQLASVDKSGITFFSPNYLQPWHNALRIAAGEAE", "output": "Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis."}]}
+{"id": "function_test_2559", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAENTMWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVETITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFTLVIDDGVNFVNQTHQTFDVIISDCTDPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQDEALDSHRKLSHYFSDVGFYQAAIPTYYGGIMTFAWATNNDALRHLSSEIIQARFHAAGLKCRYYNPAIHAAAFALPQYLHDALSAQ", "output": "Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine."}]}
+{"id": "function_test_2560", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MHQVISATTNPAKIQAILQAFEEIFGEGSCHITPVAVESGVPEQPFGSEETRAGARNRVDNAQRLHPQADFWVAIEAGIDDDATFSWVVIDNGVQRGEARSATLPLPAVILDRVRQGEALGPVMSHYTGIDEIGRKEGAIGVFTAGKLTRSSVYYQAVILALSPFHNAVYR", "output": "Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions."}]}
+{"id": "function_test_2561", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTQVYNFSAGPAMLPVEVLRRAEQELRNWHGLGTSVMEISHRSKEFMQVAEESEKDLRDLLQIPANYKVLFCHGGARAQFAAVPLNLLGDRNSADYIDGGYWAHSAIKEAQKYCTPNVIDVTTHDNGLTGIQPMKQWKLSDNAAYVHYCPNETIDGVAINEQPDFGNKVVVADYSSSILSRPIDISRYGVIYAGAQKNIGPAGLTLVIVREDLLGKAHTALPSILDYKVLADNDSMFNTPPTFAWYLSGLVFKWLKEQGGLGEMEKRNQAKAELLYGAIDRTGFYRNQVAITNRSWMNVPFQMADASLDKLFLSEAEAQGLQALKGHRVAGGMRASIYNAMPIEGVKALTDFMADFERRHG", "output": "Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine."}]}
+{"id": "function_test_2562", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRIILLGAPGAGKGTQAKIIEDKYNIAHISTGDMIRETIKSDSEIGKELKKVLDAGQLVSDEFIIKIVKDRISKDDCKNGFLLDGVPRTIIQAEELDKLGVNIDYIVEVDVKDNLLIERITGRRVHPASGRTYHTKFNPPKVEGKDDITGEDLITRTDDNEDTVRERLSVYHAQTSKLIDFYRNFSSTNTKTPKYIKIDGDQAVDKVSQDIFNQLK", "output": "Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism."}]}
+{"id": "function_test_2563", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKKKVLVGMSGGVDSSVAAYLLKEQGYEVIGVTMQIWQDDEEFIEKEGGCCSLSAVADARRVANKIGIPFYVMNFKDAFKRNVIDYFVDEYMEGRTPNPCIACNKFIKFSSFLDKAMAMGIDYVATGHYAIIEKHNDRYIIKKSEDDRKDQTYALYNLTQFQLERTLMPCGQYKKSKIREIAKEIGLRVHNKKDSEEICFIPDNDHGRYIKNRFPNKVREGNFVDKQGNILGTHKGIVYYTIGQRKGLGIAFGKPMYVVDINPFRNEVVLGDLEDLLNTELIAKDINYIPFDTLKDPMEVEAKIRYSQTPSKAIITPIEDGRVRVNFHEKQRAITKGQSVVFYKDDLLIGGGIIEK", "output": "Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34."}]}
+{"id": "function_test_2564", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGEISPLPGFSQETWEEAQSVLLAWVNNWLAGDCELPQMPSVAFGVSCALAELTDTLPQAANYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRLDANRAWTPLKGQQFAKYVNPDYRDRIAFLEEPCKTRDDSRAFARETGIAIAWDESLREPDFAFVAEEGVRAVVIKPTLTGSLEKVREQVQAAHALGLTAVISSSIESSLGLTQLARIAAWLTPDTIPGLDTLDLMQAQQVRRWPGSTLPVVEVDALERLL", "output": "Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB)."}]}
+{"id": "function_test_2565", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSDSVELYTDGACKGNPGPGGWGVLLIYKGVEKELWGGERETTNNRMELMAAIQGLMALKRECEVVLTTDSQYVMKGINEWMVNWKKRGWKTAAKEPVKNADLWQQLDEQVNRHKVTWKWVRGHIGHPGNERADQLANRGVDEVRAKR", "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."}]}
+{"id": "function_test_2566", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGKLVVQGGTVLEGEVEISGSKNAALPIMAAAILCDEEIILKNVPRLQDVFVMIDILRSIGFRVEFDENELKIKRENDISQEVPYELVRKMRASFNVLGPIAVRTGRAKVALPGGCSIGVRPVDFHLEGLKKMGFSIKVEHGFVEATFERRTDQVTITLPFPSVGATEHLMTTAALLEGTRVVIENAAMEPEIVDLQNFINRMGGRIEGAGTSRIVIEGVEKMQGVEYSIIPDRIEAGTYLVAIAASRGKGLVKNVNPDHLTNFFEKLEETGVKLKVFGNEVEIEMRERPEAVDVTTNPYPGFPTDLQPQMMAYLSIASGVSVITENVFKTRFLHVDELKRMGADIEVSGNVAIVKGVEKLSGAPVEGTDLRATAALLIAGIIADGVTEISNVEHIFRGYEDVIDKFSKLGAKIEYVEKEN", "output": "Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine."}]}
+{"id": "function_test_2567", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKYGIVGYSGRMGQEIQKVFSEKGHELVLKVDVNGVEELGSPDVVVDFSSPEALPKTVELCKKYRAGLVLGTTALKEEHLQMLRELSKEVPVVQAYNFSIGINVLKRFLSELVKVLEDWDVEIVETHHRFKKDAPSGTAILLESALGKSVPIHSLRVGGVPGDHVVVFGNIGETIEIKHRAISRTVFAIGALKAAEFLVGKDPGMYSFEEVIFGGE", "output": "Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate."}]}
+{"id": "function_test_2568", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNALLIEQLESQNMLPGDATPFEAVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRCLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRQGLSRVVLSAGARNLLQHYSFPGNVRELEHAIHRAVVLARATRSGDEVILEAQHFAFPEVTLPTPEVAAVPVVKQNLREATEAFQRETIRQALAQNHHNWAACARMLETDVANLHRLAKRLGLKD", "output": "Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54. Not required for induction of the aerobic NO-detoxifying enzyme NO dioxygenase. Binds to the promoter region of norVW, to a consensus target sequence, GT-(N7)-AC, which is highly conserved among proteobacteria (By similarity)."}]}
+{"id": "function_test_2569", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLARMAGMTSGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFATPVWHYLTLHQHDKTRTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANPAGQLLLLDEPMNSLDVAQQSALDKILSALCQQGLAIVMSSHDLNHTLRHAHRAWLLKGGKMLASGRREEVLTPPNLAQAYGMNFRRLDIEGHRMLISTI", "output": "Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system."}]}
+{"id": "function_test_2570", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTDKIVTAEEMRHYDFYTINTIGIPSLVLMERAALAVRDEILHAFPIALKDVVVVAGSGNNGGDGIAIARLLHIAGVHVTILNIGNPQHASAEHQTQEKIAQYYQIPETSDLAVLNKATLIVDAMFGIGIDRAVKGAYADAINAINNTDAVVVAVDMPSGVNTDTGEVMGTAVRATTTVTFAYNKVGLTKNDGKDYAGNVVVANDMGTYAVD", "output": "Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX."}]}
+{"id": "function_test_2571", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNIIDELKWRGALNQATDEEGLRELTEEKKIALYCGTDPSGDSLHIGHLIPFMMLKRFQLAGHKPVILIGGGTGAIGDPSGRKTERDLETRSKLEQNVQSLTKQMIRLFGTENFTIVNNYDWLSKFTMIDFLRDYGKLFNLNTMLNKEVVASRLDAGISFTEFTYQILQAIDFLHLYRHNDVQLQIGGSDQWGNITSGIDLIHKVEGSDTKVFGVTIPLMLKADGTKFGKTAGGAVWLDPEKTSPYEFYQFWLNQDDRDVVKYLKYFTFLSQEEIAGLEEKVQTEPWKREAQRRLAQEVTTFVHGQAATDQAEKISAILFSGNIQDLTTAEVEQAFAGTPSVEVSAEPANIVDWLVDTKIEPSKRQAREDVKNGAIRVNGEKVTDLEATLDPTAKFDGKYVVIRRGKKNYTLAKVHA", "output": "Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr)."}]}
+{"id": "function_test_2572", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKTETTIQGLAASLNPARAARKIIGFVPTMGNLHEGHLTLVREAKKLCDVVVVSIFVNPTQFGPGEDFDNYPRTLEQDSRLLADVGCDIIFAPSVEQMYGTQPRLTNISVSQITDDLCGSSRPGHFDGVALVVTKLFNIVQPNYAFFGQKDYQQLAVIRQFVQDLNIPLEVIGVPIVRAEDGLALSSRNGYLTPEQRQVAPVIYQGLKQAEEQLHQGKDLQQVLADLKTLLTDNGFVVDYVEARQPNLLAASQFDRDIVLFVAAKLGGTRLIDNLQVAFTPQ", "output": "Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate."}]}
+{"id": "function_test_2573", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEELIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTIRGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF", "output": "Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate."}]}
+{"id": "function_test_2574", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTTLGTPLSPSATRVLLLGSGELGKEVAIELQRFGVEVIAADRYANAPAMQVAHRSHVLDMLDPAALRVLIASERPHVIVPEIEAIHTETLVALEREQGQKVIPAARAARLTMDREGIRRLAAETLGLPTSPYRFVDTAADYREAIAAVGLPCVVKPVMSSSGKGQSTLRSEADIDAAWEYAQTGGRAGAGRCIVEGFIDFDYEITLLTVRHAGGTSYCDPIGHWQQDGDYRESWQPQPMSAAALRRSQEIAKAITDDLGGWGLFGVELFVKGDEVWFSEVSPRPHDTGLVTLVSQELSEFALHARAILGLPVGAEDGGVIGQSGPSASCALLAHGNGVPVFDNVADALRDPDTALRLFGKPRVDGHRRVGVTLARADSIDAAREKARVAAAALGIQLTA", "output": "Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate."}]}
+{"id": "function_test_2575", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAKQIQFDETARQALLRGVEQIAKAVKSTLGPAGRNVVIDKKFGSPLITKDGVTVAKEIELEDPFENMGAQLVREVSSKTNDVAGDGTTTATVLAESIYREGLRNVTAGANPISLQRGIMKAADSVVEELKKISKPVDSSKEVAQVATVSANWDAEIGNIIAEAMDKVGKDGTITVEEAKGIETTLDVVEGMQFDKGYLSPYFVTNAETMEAVLENPYILIHEKKINNLKDFLPLLEKVAKSGRPFLVIAEDIEGEALATLVVNRLRGVLNICAVKAPGFGDRRKAMMEDIAILTGGKCITEDLGIKLENVGIEDLGQAKRVVVSKDETVIVEGSAKSSDIEARISQIRRQIKDTTSDYDREKLQERLAKLAGGVAVIHVGAATETEMKEKKARVDDALHATRAAVEEGIVPGGGVALIRAQKAIDTLKLEGDEATGAQIVYRAVEAPLRQLACNAGREGALIVANVKGMKNTAEGYNVATDKYEDLLSAGVVDPTKVTRSALQNAASIAGLLLTTECVIADKPEKKSCSCGSGASDMGGMGGMGGMGMM", "output": "Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding."}]}
+{"id": "function_test_2576", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQVADKTVVIAGLGVSGTSLAEVLRERGTHVIGVDERKPEADLHSFDDVDWDHVDYVMSSPVFNPRTPFVLEAQRRGIPVMSEVEFAWQLRVNNERTGTPAPWIGITGTNGKTSTTEMTSEMLTACGLDAPTAGNIASGDMSMSLSRCATNPQHDVLCVELSSFQLHFTDSLALDCAAITNIADDHLDWHGGRENYAADKSKVFHNAKRAIVYNAQDAKVSELAAEAQTAEGCRKVGFTLEAPQAGQIGIEDGWIVDRSGVAGGAVGESVRLAAITDFTHLAEPDGSLYPHLVADALTALALVLGLGADRDTALKALTSFKPGGHRIETVAEAAVEGGSVRFVDDSKATNGHAARASLSSFPAKSVIWIAGGLAKGSRFEDLVKDQAHTIKAAVIIGKDQQPMIEAFASQAPDIPVTIIDPEDNDTVMDRAVEACGTYTAAGDIVLMAPACASMDQFKSYADRGNRFAAAAKTWSEVHGLH", "output": "Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)."}]}
+{"id": "function_test_2577", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLDIQLIRHNLAQTKQKLALRSKGLETLLDHIFELDFKKRSLQSEIEKYRALRNKQSKEIGLKKIKGENVEGQFSELKKMGSRIEEMEKELIQFENQINTLLLSLPNIPHDSVPTGGPEANKVVKTWGEPRQANFPLKTHWELGRELGILDLERGAKLSGSGFSLFTGNGAKLQRALIQFMLTIHTEEHGYKELWPPYLVTEDCMRGTGHLPKFALDMYATDKDNLYLIPTGEVPLTNFHRDEILAESSLPLRYVAYTPCFRREAGSAGKDTRGLLRLHQFDKVELVQITKPENSYTALEEMVSHAENILRSLNLCYRVVLLASQDMGFGAAKCYDLEVWSPGIQSWLEVSSVSNMENFQSRRMNLRYKSSSGKNILCHTLNGSGTALPRLVAAILENYQKEDGRVLIPEKIRTYFKEEYL", "output": "Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)."}]}
+{"id": "function_test_2578", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "PGAGSQEERMQGQMEGQDFSHEERFLSMVRE", "output": "Has antifungal activity against C.gloeosporioides but not against B.cinerea and Fusarium sp. or against various yeasts. Has no antibacterial activity."}]}
+{"id": "function_test_2579", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "GGEEQFDDYGHMRF", "output": "Myotropic peptide."}]}
+{"id": "function_test_2580", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNLNSIPAFQDNYIWVLTNDEGRCVIVDPGEAAPVLKAIAEHKWMPEAIFLTHHHHDHVGGVKELLQHFPQMTVYGPAETQDKGATHLVGDGDTIRVLGEKFTLFATPGHTLGHVCYFSHPYLFCGDTLFSGGCGRLFEGTPSQMYQSLMKINSLPDDTLICCAHEYTLANIKFALSILPHDSFINEYYRKVKELRVKKQMTLPVILKNERKINLFLRTEDIDLINEINKETILQQPEARFAWLRSKKDTF", "output": "Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid."}]}
+{"id": "function_test_2581", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGVRAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVAKEFNGDVQIELTGYWTWEQAQQWRDAGIQQVVYHRSRDAQAAGVAWGEADITAIKRLSDMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAESPVEAARQFKRSIAQLWG", "output": "Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. Is involved in the anaerobic L-ascorbate utilization."}]}
+{"id": "function_test_2582", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTAPSQVLKIRRPDDWHVHLRDGDMLKTVVPYTSEIYGRAIVMPNLASPITTVDAAIAYRQRILNAVPAGHDFTPLMTCYLTDSLDADELERGFHEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKLGMPLLVHGEVTHADVDIFDREARFIDTVMEPLRQRLTTLKVVFEHITTKDAAQYVRDGNDYLAATITPQHLMFNRNDMLVGGIRPHLYCLPILKRNIHQQALRELVASGFTRAFLGTDSAPHSRHRKETSCGCAGCFNAPSALGSYAAVFEEMNALAHFEAFCSLNGPQFYGLPVNAGWVELVRDEQQIPGNIALADDSLVPFLAGETIRWSVKK", "output": "Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate."}]}
+{"id": "function_test_2583", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSETATWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLFPFETRFVGPGHSQGMNLYLMTSPEYHMKRLLAAGCGPVFQLCRSFRNEEMGRHHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCQPAESLSYQQAFQRHLEIDPLSADKTQLREAAAKLDLSNIADTEEDRDTLLQLLFTMGVEPHIGKEKPTFIYHFPASQASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQQPIDQNLLDALAAGLPDCSGVALGVDRLVMLALGAESLADVIAFTVDRA", "output": "With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P) on 'Lys-34'. Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of EF-P 'Lys-34'."}]}
+{"id": "function_test_2584", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSQLDLNALNELPKVDRVLALAETNAQLETLTAEERVVWALENLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTGYLFPETYQFIDELTDKLKLNLKVYRAGESPAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQSGSRAHLPVLAIQRGVFKVLPIIDWDNRTVYQYLQKHGLKYHPLWDQGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECGLHEG", "output": "Catalyzes the formation of sulfite from phosphoadenosine 5'-phosphosulfate (PAPS) using thioredoxin as an electron donor."}]}
+{"id": "function_test_2585", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MHQVISATTNPAKIQAILQAFEEIFGEGSCHITPVAVESGVPEQPFGSEETRAGARNRVDNARRLHPQADFWVAIEAGIDDDATFSWVVIDNGVQRGEARSATLPLPAVILDRVHQGKALGPVMSQYTGIDEIGRKEGAIGVFTAGKLTRSSVYYQAVILALSPFHNAVYR", "output": "Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions."}]}
+{"id": "function_test_2586", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MMQPLYLVGPRGCGKTTIGMALAQATGFRFADTDRWLQSHVQMSVADIVEKEGWGGFRARETAALEAVSAPSTVVATGGGIILTEYNRRYMHRVGVVIYLCAPVSTLVNRLEAEPEADLRPTLTGKPLSEEVREVLEQRDALYRETAHYIIDATKAPAQVVSEIIAALPPSTQRLQGDVYT", "output": "Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate."}]}
+{"id": "function_test_2587", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELGAREIAEKALDIAGDICIYTNHFHTIEELTAKA", "output": "Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery."}]}
+{"id": "function_test_2588", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKNAFKDALKAGRPQIGLWLGLANSYSAELLAGAGFDWLLIDGEHAPNNVQTVLTQLQAIAPYPSQPVVRPSWNDPVQIKQLLDVGAQTLLIPMVQNADEARNAVAATRYPPAGIRGVGSALARASRWNRIPDYLHQANDAMCVLVQIETREAMSNLASILDVDGIDGVFIGPADLSADMGFAGNPQHPEVQAAIENAIVQIRAAGKAPGILMANEALAKRYLELGALFVAVGVDTTLLARGAEVLAARFGAEKKLSGASGVY", "output": "Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2-ketoheptane-1,7-dioate (HKHD) to pyruvate and succinic semialdehyde."}]}
+{"id": "function_test_2589", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSSQEASKMLRTYNIAWWGNNYYDVNELGHISVCPDPDVPEARVDLAKLVKAREAQGQRLPALFCFPQILQHRLRSINAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLAHAGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIVLEEAERLNVVPRLGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLRDAGRLDSLQLLHFHLGSQMANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNEYANNIIWAIGDACEEHGLPHPMVITESGRAVTAHHTVLVSNIIGVERNEYTDPTAPAEDAPRALQNLWETWQEMHKPGTRRSLREWLHDSQMDLHDIHIGYSSGAFSLQERAWAEQLYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFPVLPLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVGAYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTHFRDQVKQTDLDDALQQQFLEEFEAGLYGYTYLEDE", "output": "Catalyzes the biosynthesis of agmatine from arginine."}]}
+{"id": "function_test_2590", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEVNKNVFMGKLHDMVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADLMVVAGTCFTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPPRPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQPERERKRGERIAVTNLRTPDEI", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_2591", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLNIADYMDKEDFLIQIMSGEELGDIEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLHYCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVAAVNLWFLESGKSGIFNLGTGRAESFQAVADATLAYHKKSSIEYIPFPDKLKGRYQAFTQADLTNLRNAGYDKPFKTVAEGVTEYMAWLNRDA", "output": "Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose."}]}
+{"id": "function_test_2592", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTEVAEEADVLLLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGVGGCVASQEGDHIRQRAHYVDIIFGPQTLHRLPEMINAVRGNRSPVVDISFPEIEKFDRLPEPRADGPTAFVSIMEGCNKYCTYCVVPYTRGEEVSRPCDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGSFADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRVLNLMGRTHTALEYKAIIRKLREARPDIQISSDFIVGFPGETTDDFEKTMKLIADVNFDMSYSFIFSARPGTPAADMVDDVPEEDKKQRLYILQERINQQAMAWSRRMLGTVQRILVEGTSRKSLMELSGRTENNRVVNFEGTPDMVGKFVDVEIVDVYTNSLRGKIVRTEAEMGLRIAESPESVIARTRKENDLGVGIYQP", "output": "Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine."}]}
+{"id": "function_test_2593", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKVVNSKEDIRAFAENWLGKRLVTYQTDANGQPVNQILVEAATDIAKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQGRELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGADGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVLVNIFGGIVRCDLIADGIIGAVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKGLTDAAQQVVAAVEGK", "output": "Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit."}]}
+{"id": "function_test_2594", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEIFADILPLREQIKTWKREGKRIAFIPTMGNLHEGHLTLVRTAREHADIIVASIFVNPMQFNNVDDLTNYPRTIDEDIEKLTSENVDMLFTPTPEVMYPDGLDKQTVVDVPVISTILEGASRPGHFKGVSTVVAKLFNIVQPDVACFGEKDFQQLALIRQMVIDMAMDIDVVGVATVREMDGLAMSSRNNLLTLNERQRSPVLARTMRWISSQMRRGRNDYESLIEDASDQLRAADLQPDEIFIRDARTLQEPTEETTQAVILMAAFLGQVRLIDNLVVELTTAANEEEEEEEEEEK", "output": "Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate."}]}
+{"id": "function_test_2595", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MFYWLTELAGTIPGINVFRYITFRTGGAMVTGALFVFLFGPWIIDHLRLAQGKGQPIRADGPPTHLMTKKGTPTMGGLMILSGLVVSTLLWANLHNPYVWVVLMVTLGFGFVGFYDDYLKVTKQTHAGFSGRLRLAVEGLIALFACLVIIWAGRDSSVMHLGIPFAKDFAINLGWFYLVFGAFIIVGAGNAVNLTDGLDGLAIVPVMIAAASFGMIAYLVGNAVFSEYLQIRYVAGTGELAVLCGAVLGAGLGFLWFNAPPASIFMGDTGSLALGGMIGSIAVAVKHEIVLAVIGGLFVFEALSVIVQVASFKLTGKRIFRMAPIHHHYEQKGWTEPQIVIRFWIIAVMLALAGLSTLKLR", "output": "Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I."}]}
+{"id": "function_test_2596", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKLAGIDEAGRGPVLGPMVIAAVVVDEGNVPKLEELGVKDSKKLTPKRRERLFDEIVQLLDDYVILELWPEEIDSREGTLNEFEVENFVKALNSLKVKPDVVYIDAADVKEARFGEEIKAKLDFEADIIAEHKADDKFVPVSAASILAKVARDRAIEKLKDQYGEIGSGYPSDPRTRTFLEEYYRKHGEFPPIVRRTWKTLKKIEEKLAKEMKKRRGQTSLEEFFGK", "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."}]}
+{"id": "function_test_2597", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPDYRSKTSTHGRNMAGARGLWRATGMKDEDFGKPIIAVVNSFTQFVPGHVHLKDLGQLVAAEIQAAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSRDLIADSVEYMVNAHCADAMVCISNCDKITPGMLMAAMRLNIPVVFVSGGPMEAGKVKFRGDEKAIDLVDAMVVAADDSYTDEEVAEFERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGSIVATHANRKKLFLKAGQLIVELAKRYYEQNDASILPRSIATKAAFKNAMTLDIAMGGSTNTVLHLLAAANEAEVDFTMDDIDELSRRVPVLSKVAPAKQDVHMEDVHRAGGIMAILGELDRANLLDVSVPTVHEKTLKDALDKWDIIRTEDPDVYEFYRSSPGGVPTQVAFSQNRYYSTLDGDREKGVIRNAEHAFSKDGGLAVLYGNIALDGCIVKTAGVDESILKFTGSARVFESQDAAVEAILGNEIKAGDVVIIRYEGPRGGPGMQEMLYPTSYLKSKGLGKDCALVTDGRFSGGSSGLSIGHVSPEAAEGGAIGLVEDGDTIEIDIPNRTIHLNIDDATLAHRRTVQEAKGWHPKEERKRKVSKALKVYAMHTTSAAKGAVRVL", "output": "Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively."}]}
+{"id": "function_test_2598", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRIIGVDPGYGILGYGILEKNKNKISHVTHGVITTEKDVPMYKRLGYIYDRFVELLEEYSPDACAIESLFFYKNVKTAIHVGEARGVILLASSQRNIPLYEFTPYQVKNNVTGYGRADKKQVQKMVKMLLNLNDIPKPDDAADALAVAWCLAVEIKA", "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair. Endonuclease that resolves HJ intermediates. Cleaves cruciform DNA by making single-stranded nicks across the HJ at symmetrical positions within the homologous arms, yielding a 5'-phosphate and a 3'-hydroxyl group; requires a central core of homology in the junction. The consensus cleavage sequence is 5'-(A/T)TT(C/G)-3'. Cleavage occurs on the 3'-side of the TT dinucleotide at the point of strand exchange. HJ branch migration catalyzed by RuvA-RuvB allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."}]}
+{"id": "function_test_2599", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNYLEFEVIWGVNNIYSILELNSKLIYEGIFKGKVLETGCKEYSPLVPGDIVLGYIYSSRKVYIDKRLSRKNILWRYNKKADLRQTIVSNIDNVLIVSSANFPEMKNFFIDRVLIVAEEQNIVPIIVINKIDKGISQKAQEFSEIYENLGYKVLKTSVKTYEGIKEVKEVLKNSRTSFIGQSGVGKSSLINLIDSRASQSVNEISHKYSRGKHTTVYSISFHSDSGIIVDTPGIKEFGIETLPFENLKYYFKEFENFASFCKYKSCLHVSEPYCSVTSSLDNGISKLRYESYLKILSELKNYKNYAR", "output": "One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit."}]}
+{"id": "function_test_2600", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEYQTLWQRYLDWLYYHQNLGFYVDISRIRFDDAFIDSIKPKFEKAFKDMEELEKGAIANPDEGRMVGHYWLRAPELAPNDEVRKEITEPLKQIEEFVAKVLKGTIKPPTADKFTDIISVGIGGSALGPQFVSEALAGDFPPMGIHFIDNTDPAGIDRVVTRLKDRLKSTLVIVTSKSGGTPETRNGMLEMRHAYEKNGLDFPKYAVAVTMPGSKMDQVAHDWLARFPMQDWVGGRTSELSAVGLLPAALQGIDIQGMLAGAKEMDEATRVKDLKNNPSALLALSWYYAGNGKGEKDMVVLPYKDSLALLSRYLQQLVMESLGKEKDLDGNTVYQGIAVYGNKGSTDQHAYVQQLREGVPNFFVTFIEVLEDRQGSSIELEPGVTSGDYLAGFIQGTRQALYENHRDSITITIPEVNPRTVGALVALYERAVSFYGSLVNVNAYHQPGVEAGKKAAASILELQQNVMKALKEAGTELDLETLSQKAGHPDKVEAVYKIVRHLAANNRGVMLKGDLGKPTTLKVSFG", "output": "Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate."}]}
+{"id": "function_test_2601", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQCLAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVRHLDGEDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA", "output": "Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O."}]}
+{"id": "function_test_2602", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNVSVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFKRPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA", "output": "Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs."}]}
+{"id": "function_test_2603", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDDVSGFENPEGSLTGGIQATGNYPGKARNASELRADLEQAMRLIPGPKRLNLHAIYLESDTPVARDQIKPEHFKNWVEWAKANQLGLDFNPSCFSHPLSADGFTLSHADDSIRQFWIDHCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLDPAHHIDAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAAMLYVPQLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHDLFDRVHIGLDFFDASINRIAAWVIGTRNMKKALLRALLEPTTELRKLEAAGDYTARLALLEEQKSLPWQAVWEMYCQRHDTPAGSEWLESVRAYEKAILSQRG", "output": "Catalyzes the interconversion of L-rhamnose and L-rhamnulose."}]}
+{"id": "function_test_2604", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIENVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFARRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQPMPAFPYTADYFSGLTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNGGEMCPRMSKGKDPYYAGCGLYKCADGYIVMELVGITQIEECFKDIGLAHLLGTPEIPEGTQLIHRIECPYGPLVEEKLDAWLAAHTIAEVKERFAELNIACAKVLTVPELESNPQYVARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDIQELVSKGLAKVED", "output": "Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA."}]}
+{"id": "function_test_2605", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEMSPQVTWGTNPGQVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK", "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."}]}
+{"id": "function_test_2606", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAAVSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF", "output": "Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate."}]}
+{"id": "function_test_2607", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MENNKKQGVLLVNLGTPDSATPAGVRRFLSEFLHDKRVVNLTRWLWCPILHGVILPIRAPKVAKLYQSVWMDEGSPLLVYSQRQAEKLQKKLQIPVALGMTYGNPSLKTGVEQLMDQGVEDIIVLPLYPQYSGTTTAAVSDGLTKAFKQMPVIPSYRFIRDYYAHPSYAKALAESVRSHWDKNGRADHLVCSFHGIPKRLADEGDIYPQHCEATTELLAAELGLSADDITMTYQSRFGREEWLKPYTDETLESLPSKGIKKIDIMAPAFSVDCLETLEEISDQCKETFIDAGGSDFSYITCLNDRDSHIDMMAELVALYR", "output": "Catalyzes the ferrous insertion into protoporphyrin IX."}]}
+{"id": "function_test_2608", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAGAAALRRSARRVVRPGAYALSRALQHPERLLSSQASPDRGGVLGSELGRYPPERVRNFSIIAHVDHGKSTLADRLLELTGTIKKGHGQPQYLDKLQVERERGITVKAQTATMFYRHANNQLPASDQPDAPSYLLNLIDTPGHVDFSYEVSRSLAACQGALLVVDAAQGVQAQTIANFYLAFESNLSIIPVINKIDQPTADPDNVKAQLKRLFDIDPSEALLTSAKTGQGLSQVLPAVIERIPSPPGKCDSPVRMLLLDSYYDEYKGVICHVAVVDGALHKGDKIASAATGRTYEVLDVGIMHPELTPTGVLYTGQVGYVISGMRSTKEARIGDTLHQAKSIVEPLPGFKPARHMVFSGLYPADGSDFDALSHAIEKLTCNDASVSVTKETSTALGMGFRCGFLGLLHMDVFHQRLEQEHGAQVISTIPTVPYIFEYGDGSKVQVENPAALASNPGKRIAACWEPTVIATIIIPKVLRLPNRFFSQRALLKYRLPLREIIVDFYNELKSITSGYATFDYEDSEYQQSDLVKMDILLNGQPVDAMATIVHNQKAQRVGRELVDKLKKFIERQMFEITIQAAVGSKVIARETLSAMRKNVLAKCYGGDITRKKKLLEKQKEGKKRMKRVGSVDIPQEAFHELLKVSNSK", "output": "Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner."}]}
+{"id": "function_test_2609", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMGATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYADSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQLAVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFFPDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQRAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQERKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD", "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage."}]}
+{"id": "function_test_2610", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLLLELLKALILGIVEGLTEFAPVSSTGHMILVDDMWLKSPEFLGSQSAFTFKIVIQLGSVFAAAWVFRKRYFEMLYIGKYQPAATETESADGKIGKRVKPKRLTLWHVLVGMIPAGILGLLFDDVIEKYLFSVPTVMIGLLLGAFYMIFAQKFSERYAHRENIDQITFFQAFVIGLSQAVAMWPGFSRSGSTISTGVLMKMNYKAASDFTFIMAVPIMLAASLLSLVKHIGYIHLSHIPFYIIGFLAAFIFGLLSIRLFLNLINRIKLIPFAIYRIILVIFIAILYFGFGIGKGI", "output": "Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin."}]}
+{"id": "function_test_2611", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKNIGILGASGSVGTQGLDIIRQYPDTYKLVSFSVGKNLELANKIIEEFRPDICCVQDKEDIDKIQSSSIKVVYGNDGLMEIAAYVKNDMLLNSIMGSIGLKPTVHAIKHGIDIALANKETLVVAGEIIMQLAREYNVNIIPVDSEHSAIFQCLNGEDHKHIEKLIITASGGSFRELSREALKDVTVQDALKHPNWSMGKKITIDSATMMNKGLEVIEARWLFDMPIDKIETLLHKQSIIHSMVEFNDTSVIAQLGTPDMRMPILYAFSYPDRLARKAERLNLAEVGQLDFKAMDFDRYRCLKLAYDAISIGGTMPVVMNAVNEVVVQQFLDGEIGFLDIETIIEREMNAHDVIQSPDLETILEIDAQYKSRKYEV", "output": "Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)."}]}
+{"id": "function_test_2612", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKREKKDYYEILGVPRNATQEEIRKAYKRLVKEWHPDRHPENRKEAEQRFKEIQEAYEVLSDPQKRAMYDRFGYVGEQPVYQEAETGGSFFEDVFREFENIFNRDIFDVFFGEESGRRERREYARRGEDIRYTIEVNLSDLINGTEIPIEYERYETCPRCGGTGVEPDSGYISCPRCGGTGRIREEKRSFFGYFVSERTCDECGGTGRVPQELCHECGGSGRVLRRVRRTIKIPPNIEDGGHLRIPGGGNAGYYGGPYGDLIITVRVRSDSRFKRSGKDLIYDITIDYLQAILGTTVEIPLPEGGTTMLKIPPGTQPETVFRLKGKGLPGEYGRRGDLLVNVHVEIPKNLSREERKVLEDLAKKRGIPVA", "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins."}]}
+{"id": "function_test_2613", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MMKRQFEDVKRIVIKIGTSSLVLANGKINLEKIDHLAFVISSLMNKGKEVILVSSGAMGFGLDLLKMAKRPSQLAKQQAVSSVGQVAMMSLYSQIFAHYQTTVSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHSTKFGDNDRLSAIVARITRADLLIMLSDIDGLFDKNPTIYEDARLRSHVTEITEDIIASAGGAGSRFGTGGMLSKIQSAQMMFEHQGQMILMNGANPRDILRVLEGEKLGTWFKQIERGDA", "output": "Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate."}]}
+{"id": "function_test_2614", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKLVLVVLAFIALVSSVSCTQTGGCSCGQQQSHEQQHHPQQHHPQKQQHQPPPQHHQQQQHQQQQVHMQPQKHQQQQEVHVQQQQQQPQHQQQQQQQQHQQQHQCEGQQQHHQQSQGHVQQHEQSHEQHQGQSHEQQHQQQFQGHDKQQQPQQPQQYQQGQEKSQQQQCHCQEQQQTTRCSYNYYSSSSNLKNCHEFLRQQCSPLVMPFLQSRLIQPSSCQVLQQQCCHDLRQIEPQYIHQAIYNMVQSIIQEEQQQQPCELCGSQQATQSAVAILTAAQYLPSMCGLYHSYYQNNPCSSNDISGVCN", "output": "Zeins are major seed storage proteins."}]}
+{"id": "function_test_2615", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MERITVTLGERSYPITIAAGLFNEPASFLPLKSGDQVMLVTNETLAPLYLDKVRGVLERAGVNVDSVILPDGEQYKSLTVLDTVFTALLKKPHGRDTTLVALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPARELASGLAEVIKYGIILDADFFTWLEGNLDALLRLDGPAMAYCIRRCCELKAEVVAADEREAGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGIVMAARASERLGQFSSADTQRIIALLERAGLPVNGPCEMSAQDYLPHMLRDKKVLAGELRLVLPLAIGKSEVRGGVSHEVVLSAIADCQQA", "output": "Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)."}]}
+{"id": "function_test_2616", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEDFIKGLAERVLEGEKLSKEDGLKILSIPDEYLDLLVQEASKVREAVFGDEVEFCSLINAKNGACSEDCSFCAQSSKYPTPINAYGLVPKKELVEGAQKAVSIKANRYCIVTSGKRATKEEVEQIADAVREITENLPVRVCVSIGTVDEEDLKLLKDSGVDRVNHNLETSERHFKNIVTTHSYKERLETIKTVQKVGLSTCTGGIFGIGETDEDIVDLASVYRELNVNSIPMNFLIPIPGTPLEGNKQLTPQRCLKIISLFKLFNPQAELRLCGGREINLREYHDTAMEIANCVMAGGYLTRAGRAPGKDEEMVRRLGRKLITGRDLFSKYKTAV", "output": "Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism."}]}
+{"id": "function_test_2617", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPAIVLIGAQWGDEGKGKATDLLGEQLQWVVRYQGGNNAGHTVVLPNGDKFALHLIPSGILTPAVNNVIGNGVVVDPGVLLTELAGLEERGVDTSRLLLSADAHLIMPYHVAIDKVTERFLGAKKIGTTGRGIGPCYQDKIARVGVRAADVLDEKILTQKVEAALEFKNQVLVKIYNRKALDPQQVVEEVLTQAEGFKHRISDTRLELNLALERGETVLLEGSQGTLLDVDHGTYPYVTSSNPTSGGAAVGSGIGPTKITTVLGILKAYTTRVGSGPFPTELFDDHGAYLAKQGGEVGVTTGRARRTGWFDAVIARYATRVNGITDYFLTKLDVLSSLDTVPICVAYEVDGVRHDEMPMSQSDIHHAKPIYEEMPGWWEDISEARTFEELPQNAQNYVLRLEELSGAFISCIGVGPGRDETIVRREIVR", "output": "Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP."}]}
+{"id": "function_test_2618", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTAEGSGSSTAAVASHDPSHTRPSRREAPDRNLAMELVRVTEAGAMAAGRWVGRGDKEGGDGAAVDAMRELVNSVSMRGVVVIGEGEKDHAPMLYNGEEVGNGDGPECDFAVDPIDGTTLMSKGMTNAISVLAVADRGTMFDPSAVFYMNKIAVGPDAAHVLDITAPISENIRAVAKVKDLSVRDMTVCILDRPRHAQLIHDVRATGARIRLITDGDVAGAISACRPHSGTDLLAGIGGTPEGIIAAAAIRCMGGAIQAQLAPRDDAERRKALEAGYDLNQVLTTEDLVSGENVFFCATGVTDGDLLKGVRYYPGGCTTHSIVMRSKSGTVRMIEAYHRLSKLNEYSAIDFTGDSSAVYPLP", "output": "Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate."}]}
+{"id": "function_test_2619", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVEHAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNLALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGGATIADVRLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADGDY", "output": "Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate."}]}
+{"id": "function_test_2620", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSSAAMVKAEDSLEPTLQNLLDQKTLRWVFVGGKGGVGKTTTSCSLAIQLAKVRKSVLLISTDPAHNLSDAFGQKFGKEARLIDGFTNLSAMEIDPNGSIQDLLAAGGGQGDDSMGGLGIGGMMQDLAFSIPGVDEAMSFAEVLKQVKSLSYEVIIFDTAPTGHTLRFLQFPTVLEKALAKLAQLSTQFGPMLNSILGGRGGLPGGQNLDEILSKMESLRETIAEVNAQFKDADLTTFVCVCIAEFLSLYETERMIQELTSYHIDTHCIVVNQLLFPGKDSSCEQCKARRKMQKKYLNEIEELYEDFNVVRMPMLVEEVRGKEKLEKFSDMLIHPYVPPQE", "output": "ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting."}]}
+{"id": "function_test_2621", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSIVRSDKPFVLAGRTYQSRLLVGTGKYRDMEETRLAIEASGAEIVTFAVRRTNLGQIEGEPNLLEVLSPDRYTFLPNTAGCYDAIEAVRTCRLARELLDGHNLVKLEVLADQKTLFPNVIETLKAAETLVKEGFDVMVYTSDDPIIARQLAEIGCIAVMPLAGLIGSGLGICNPYNLQIILEEAKIPVLVDAGVGTASDATIAMELGCDAVLMNSAIAHAQQPIMMAEAMNHAIVAGRLAYLAGRMPKKLYASASSPLDGLIK", "output": "Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S."}]}
+{"id": "function_test_2622", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKAIYDLPAPAKLNLFLHITGRREDGYHLLQSVFMLIDWCDTLHVELRSDGQLSREDLTTELPPDDLVLRAARALQAHAAPGQGAHIGIAKQVPAQAGMGGGSSDAATCLLALNRLWGLDLPLSRLAEIGVQLGADVPFFLGGRNAWVEGIGEKIRPVDIPSARFVVAKPPQGLDTKLIFSAPDLQRATPVAIISGFAADSEQLEAPNPESSAFKVFDFGHNDLQPVAQRLCPAVTDAIEWLGAQGLKARMTGSGSSVFAKMPQGPQEAELAKAPPGWQVRQCSNLAVHPLWGWAT", "output": "Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol."}]}
+{"id": "function_test_2623", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRGCLQSVKWLTSAVRQSQSLTSSTRFPRRLFNTSTLHYAQGRKPVSELEQRIAAIPIERFRNFCIVAHVDHGKSTLSDRLLELTGTIEAGANKQVLDKLDVERERGITVKAQTCSMLYNHQGEDYLLHLVDTPGHVDFRAEVSRSYASCGGALLLVDASQGIQAQTVANFYLAFAEGLKLVPVINKVDLPSADPERALDQMKNTFELDPKSAVLVSAKTGLNVEQLLPTVIEQVPAPVGDHTKPLRMLLVDSWYSTYKGVILLVRIFDGEVRAGDQVVSFATGLKYFVGEVGIMYPGQTAQSVLRAGQVGYIYFNPAMKRSQEAKVGDTYTKVGSEKLVQPLPGFEEPKAMVFVAAYPVDASDFPHLEDSINQLTLNDRSVTLQKESSEALGAGFRLGFLGTLHCSVFEDRLRQEHGASIIITPPTVPFKVIWKDGKEEIVTNPALFPEEETLRAKVAELQEPFVLATLTFPEEYLGRVIELCESNRGEQKNLEFFTSTQVILKYELPLAQLVDDFFGKLKGSTKGYASLDYEESGWRRSNISKLQLLVNKVPVDAVSRVVHASQVQRLGRLWVSKFKEHVDRQMFEIVIQAAVGRNVVARESIKPFRKDVLQKLHASDITRRKKLLEKQKEGRKRLKAVGNVVIEHKAFQAFLAK", "output": "Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner."}]}
+{"id": "function_test_2624", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNPLIIKLGGVLLDSEEALERLFTALVAYRQEHQRPLVIVHGGGCLVDDLMKKLSLPVVKKNGLRVTPADQIDIITGALAGSANKTLLSWAKKHDINAVGLCLGDGGSTTVTQLDEALGFVGKAEAGSPALLNTLLSAGYLPVVSSIGITAQGDLMNVNADQAATALAQTLGADLILLSDVSGILDGKGQRIAEMTAEKAEQLIAQGIITDGMIVKVNAALDAARALGRPVDIASWRHAEQLPALFNGVAIGTRILA", "output": "Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate."}]}
+{"id": "function_test_2625", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTWPLPDRLSINSLSGTPAVDLSSFTDFLRRQAPELLPASISGGAPLAGGDAQLPHGTTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRSGADTFGSDGGEK", "output": "Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation."}]}
+{"id": "function_test_2626", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MATLAMSTPSSPTWPKRRPKAWAMRCERYCCAAASYFPLAFVYSLTTWAVYVEASVGLKPSSSSWIGLPSSILGVVLYLALNISYTTAVFTDPGSPLGARSGGGHPYSALPITELPEYTSYTVNSTGGSRFCKKCQCPKPDRAHHCSTCKRCVLKMDHHCPWLATCVGLRNYKAFLLFLIYTSLFCWVDFGVSAIWIWTEVFNDTRYMDGILPVNVVLLSILGGIIGLVLTGFTAWHISLATRGLTTIECLEKTRYVSPLRKALDRHRYDGLLGTNTGGENQDTFGSRLQNYGNQILDAHANAIPGVTRPEEGEESSDNLTPAQQALSRSYADLERQREHDRYEDYLAELDNEKMPHAFDLGWKRNLLHLFGDRPLHWLVPTPTTTGNGWEWEPSRKFLEAQERVRQQREQVAEQQRQHQRDLYLRNMNNSRAWLGNELPPGWTPDQPLSHSDDVARPATGVSMKTLAPRSPRPRPGEEVYAEDLDKDDFVLEPTRGKGSGNQSSREDDWRDWD", "output": "Palmitoyltransferase specific for VAC8. Palmitoylates VAC8 at one or more of its N-terminal cysteine residues, which is required for its proper membrane localization (By similarity)."}]}
+{"id": "function_test_2627", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAESWVIMVTAQTPINIAVIKYWGKRDETLILPINDSIRVSLDPDHLCTTTTVSVRPSFEQDRMWLNGKEISLLGGRFQSCLREIRSRARDLEDEKKGIVIKKMDWEKLHFHIASYNNFPTAAGLASSAAGLACFVFALAKLLTLQEDNGQLSAIARRGSGSACRSLYGGFVKWIMGKEENGSDSIAVQLADEKHWDDLVIVIAVVSARQKETSSTTGMQDSCKTSMLIQHRAKEVVPKRILQMEDAIEKRDFPSFARLACADSNQFHAVCLDTSPPIFYINDTSHKIISCVEKWNRSVGTPQVAYTFDAGPNAVLIARDRKIAALLLRRLLFHFPPHSNTDSNSYVIGDKSILQDVGVQDTKDIESLPPPPEIKDNIPAQKSNGDVSYFICTRPGRGPVLLPDSRALLNPETGLPK", "output": "Performs the first committed step in the biosynthesis of isoprene-containing compounds such as sterols and terpenoids (By similarity). Component of the triterpene saponins (e.g. ginsenosides or panaxosides) and phytosterols biosynthetic pathways . Catalyzes the conversion of mevalonate diphosphate to isopentenyl diphosphate (IPP) ."}]}
+{"id": "function_test_2628", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDDRVHPEVRRTATEIDTMEIRGAATIADAAARALRTQATESDAADAEAFRAELRATARTLHETRPTAVSLPNALRYVLRDMSSTTVEGLRQSVVDSADEFCARLERAQADLGQVGANRLRDGDTIMTHCHSTDALACVEAAVEQGKHIEAVVKETRPRNQGHITAKRLHELGVPVTLIVDSAARRYLNDVDHVLVGADAVAADGSVINKIGTSGLAVNARERGTPIMVAAQTLKLHPGTMTGHTVDIEMRDTAEVVDDDTLADLGNPTVKNPAFDVTPPRYVDAIVTERGQFPPESIVILMRELFGEGTSEPWAEPSPRAEP", "output": "Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO."}]}
+{"id": "function_test_2629", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLNRYPLWKYLMVFFAIITAALYALPNIYGEDPAIQVTGARGASVDMSTLDAVTTALDKEQLSHKSIALENGSILVRFNDTDTQISARDVISEALGKDTIVALNLAPSTPDWLEAIGASPLKLGLDLRGGVHFLMEVDMDAAMEKLVGQQEEAFRSELREAKIRYRAIRPSGKEAVEVLLRNEEQLAEAKAMLEKNHPDMLFVESDSNGRYALTATFTEQRLQEIRNYAVEQNITILRNRVNELGVAEPLVQRQGASRIVVELPGVQDTARAKEILGATATLEFREVDDKADLSAAANGRAPAGSEIKMDRDGRPVVLKKRVILGGQSITDASSSVDEYGRPQVNISLDSEGGNKMSAFSKKNIGKLMATVFAEYKDSGRRTPEGKVILDKHEEVINQATIQSALGRNFRITGIDSAAEAHNLALLLRAGALIAPISIVEERTIGPSMGQQNIDMGIQACIWGMVAVMLFTLLYYRGFGLIANIALMANLVLIIGVMSMIPGATMTLPGIAGIVLTVGMAVDANVLIFERIREELRDGRSPQQAIHQGYANAFSTIADANITTLITAIILFAVGTGAVKGFAVTLSIGILTSMFTAIIGTRCIVNLIYGGKRVDKLSI", "output": "Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity).; "}]}
+{"id": "function_test_2630", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "IKYMTDGMLLREGMTDPLLERYGVILLDEAHERTVATDILMGLLKEVEKQRSDLKLVVMSATLDAGKFQHYFDNAPLMTVPGRTHPVEIFYTPEPERDYLEAAIRTVVQIHMCEEVEGDVLLFLTGQEEIEEACKRIKREVDNLGPEVGDLKTIPLYSTLPPAMQQRIFEHAPPNKANGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVSPISKASAQQRVGRAGRTRPGKCFRLYTEKAYDSEMQDNTYPEILRSNLGTVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLGALDDSGDLTRLGSMMAEFPLDPQLAKMVIASTDYSCSNEILSVTAMLSVPQCFLRPNEAKKLADEAKMRFAHIDGDHLTLLNVYHAFKQNNEDPQWCYDNFIQYRSLKSADSVRQQLARIMDRFALQRTSTNFNSKDYYL", "output": "Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA."}]}
+{"id": "function_test_2631", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNNERLRRTMMFVPGNNPAMVKDAGIFGADSIMFDLEDAVSLAEKDSARYLVYEALQTVDYGSSELVVRINGLDTPFYKNDIKAMVKAGIDVIRLPKVETAAMMHELESLITDAEKEFGRPVGTTHMMAAIESALGVVNAVEIANASDRMIGIALSAEDYTTDMKTHRYPDGQELLYARNVILHAARAAGIAAFDTVFTNLNDEEGFYRETQLIHQLGFDGKSLINPRQIEMVNKVYAPTEKEINNAQNVIAAIEEAKQKGSGVISMNGQMVDRPVVLRAQRVMKLANANHLVDSEGNYIEK", "output": "Represents a citryl-ACP lyase."}]}
+{"id": "function_test_2632", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSIFEYNGSALVAMVGKNCFAIASDRRLGVQLQTIATDFQRIFKIHDKLYVGLSGLATDVQTLYQRFAFRHKLYQLREERNMRPETFASLVSALLYEKRFGPYFCQPVIAGLGEDDKPFICTMDSIGAKELAKDFVVAGTAAESLYGACESMYKPDMEPEELFETISQALLSSIDRDCLSGWGGHVYVVSPNQVIERTLKGRMD", "output": "Non-catalytic component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity."}]}
+{"id": "function_test_2633", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDLSVELFGIRFKNPVWVASGTFGYGVEAAEIYDISKLGAVVTKGLSLKERLGNETPRIVETPCGMLNSIGLQNPGVEKFLKEIYPKIKDVDTHFIANVFGETEEEYVEVCMALEDADKIVAYELNVSCPNVKKGGILFGHDPVILGNLVDRIKAKIKKPLLVKLSPNVTDVTEFAKVCIENGADGLVLINTLMGMKINIWKRKPDLATKTGGLSGPAILPIAVRMIYQVYEKFGDRIPIIGVGGITTWEDAMEHVMAGASAVQVGTANFYEPLAPLKVIEGIENFMKSQNIKDFKELIGIAHRVE", "output": "Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor."}]}
+{"id": "function_test_2634", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAHPTQLGFQDAASPVMEELLHFHDHALMIVFLISTLVLYIIIAMVSTKLTNKYILDSQEIEIVWTILPAVILVLIALPSLRILYLMDEINDPHLTIKAMGHQWYWSYEYTDYENLGFDSYMVPTQDLAPGQFRLLETDHRMVVPMESPVRILVSAEDVLHSWAVPSLGVKMDAVPGRLNQTAFIASRPGVFYGQCSEICGANHSFMPIVVEAVPLEHFENWSSLMLEDA", "output": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix."}]}
+{"id": "function_test_2635", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAQQLSARQPRYKRILLKLSGEALMGSEEFGIDPKVLDRMALEIGQLVGIGVQVGLVIGGGNLFRGAALSAAGMDRVTGDHMGMLATVMNGLAMRDALERSNIPALVMSAISMVGVTDHYDRRKAMRHLGGGEVVIFSAGTGNPFFTTDSAACLRAIEIDADVVLKATKVDGVYTADPFKDPNAEKFERLTYDEVLDRKLGVMDLTAICLCRDQNMPLRVFNMNKPGALLNIVVGGAEGTLIEEG", "output": "Catalyzes the reversible phosphorylation of UMP to UDP."}]}
+{"id": "function_test_2636", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKCAHFIDGPHCVKACPAGVLGENDTLVRKYADANAVCQLCHPNCTRGCKGPGLEGCPNGSKTPSIAAGVVGGLLCLVVVGLGIGLYLRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQAHLRILKETEFKKVKVLGSGAFGTIYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPYGCLLDYIREHKDNIGSQYLLNWCVQIAKGMNYLEERRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGADEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSVLEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIAEFSKMARDPPRYLVIQGDERMHLPSPTDSKFYRTLMEEEDMEDIVDADEYLVPHQGFFNSPSTSRTPLLSSLSATSNNSATNCIDRNGQGHPVREDSFVQRYSSDPTGNFLEESIDDGFLPAPEYVNQLMPKKPSTAMVQNQIYNFISLTAISKLPMDSRYQNSHSTAVDNPEYLNTNQSPLAKTVFESSPYWIQSGNHQINLDNPDYQQDFLPTSCS", "output": "The v-erbB oncogene transforms avian fibroblasts and erythroblasts in culture and induces sarcomas and erythroleukemias in chickens. It is a truncated and mutated version of the receptor for epidermal growth factor."}]}
+{"id": "function_test_2637", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "RTCYKTPSVKPETCPHGENICYTETWCDAWCSQRGKRVELGCAATCPKVKAGVGIKCCSTDNCNPFPVWNPRG", "output": "Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission."}]}
+{"id": "function_test_2638", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPPNFGGFFMVRSYYPSECHADYFDFERIEALKPAIEACGISTLSQSPMLGFHKQMDNRIKLLEEILSFRMQGVEFDNGDMYVYGHKAASDVRDEFVSVTEKLMDELAQCYNVLPQLDINNTIDHPPEGDEKWFLENEKTVTQFCRKLAAERPLKDIRDEYNYPKKKGIKDECSRLLEASTMKSRRGFTIQRLMNAMRQAHADGWFIVFDTLTLADDRLEAFYDNPNALRDYFRDIGRMVLAAERRKANDSHADCYQYFCVPEYGTANGRLHFHAVHFMRTLPSGSVDPNFGRRVRNRRQLNSLQNTWPYGYSMPIAVRYTQDAFSRSGWLWPVDAKGEPLKATSYMAVGFYVAKYVNKKSDMDLAAKGLGAKEWNNSLKTKLSLLPKKLFRIRMSRNFGMKMFTMTNLSMECLIQLTKLGYDATPFNQILKQNAKREMRLRLGKVTVADVLAAQPVTTNLLKFMRASIKMIGVSNLQSFIASMTQKLTLSDISDESKNYLDKAGITTACLRIKSKWTAGGK", "output": "The A protein is a specific endonuclease that cleaves the viral strand of supertwisted, closed circular DNA at a unique site in the A gene. The A protein also causes relaxation of supertwisted DNA and forms a complex with viral DNA that has a discontinuity in gene A of the viral strand.; "}]}
+{"id": "function_test_2639", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTATFDKVADIIAETSEIDRATITPESHTIDDLGIDSLDFLDIVFAIDKEFGIKIPLEKWTQEVNEGKVSTEEYFVLKNLCAKIDELKAAKA", "output": "Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is involved in the transfer of long hydroxylated fatty acids to lipid A. Is acylated predominantly with 27-hydroxyoctacosanoic acid (By similarity)."}]}
+{"id": "function_test_2640", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPTIQQLVRKGRQDKVEKNKTPALEGSPQRRGVCTRVFTTTPKKPNSALRKVARVRLTSGIEVTAYIPGEGHNLQEHSIVLVRGGRVKDLPGVRYKIIRGSLDTQGVKNRKQARSRYGAKKEK", "output": "With S4 and S5 plays an important role in translational accuracy.; "}]}
+{"id": "function_test_2641", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAGEAPAAPQVTAEDASASLAELLNAGLGGSDNE", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_2642", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "FLSLIPTAINAVSAIAKHF", "output": "Antimicrobial peptide with low activity against Leishmania species (L.amazonensis and L.infantum) . Shows low cytotoxicity against mammalian cells in models of peritoneal macrophages ."}]}
+{"id": "function_test_2643", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "ADGIFAIDQFTKVLLNYTGHITWNPPAIFKSYCEIIVTYFPFDEQNCSMKLGTRTYDGTVVAIYPEGPRPDLSNYMQSGEWALKDYRGFWHSVNYSCCLDTPYLDITYHFILLRLPLYFIVNVIIPC", "output": "Upon acetylcholine binding, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity). Does not bind alpha-bungarotoxin."}]}
+{"id": "function_test_2644", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "TPEHQRYIELFLVVDSGMFMKYNGNSDKI", "output": "Snake venom zinc metalloproteinase that impairs hemostasis in the envenomed animal."}]}
+{"id": "function_test_2645", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAGRSGDSDEDLLKTVRLIKFLYQSNPPPSNEGTRQARRNRRRRWRERQRQIRTISERILSTYLGRPAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGNPEILVESPTVLESGTKE", "output": "Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells. These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts). This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs. Rev itself is translated from a fully spliced mRNA that readily exits the nucleus. Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1. KPNB1 binds to the GDP bound form of RAN (Ran-GDP) and targets Rev to the nucleus. In the nucleus, the conversion from Ran-GDP to Ran-GTP dissociates Rev from KPNB1 and allows Rev's binding to the RRE in viral pre-mRNAs. Rev multimerization on the RRE via cooperative assembly exposes its nuclear export signal (NES) to the surface. Rev can then form a complex with XPO1/CRM1 and Ran-GTP, leading to nuclear export of the complex. Conversion from Ran-GTP to Ran-GDP mediates dissociation of the Rev/RRE/XPO1/RAN complex, so that Rev can return to the nucleus for a subsequent round of export. Beside KPNB1, also seems to interact with TNPO1/Transportin-1, RANBP5/IPO5 and IPO7/RANBP7 for nuclear import. The nucleoporin-like HRB/RIP is an essential cofactor that probably indirectly interacts with Rev to release HIV RNAs from the perinuclear region to the cytoplasm."}]}
+{"id": "function_test_2646", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPRYKTVEQVLSLMKDVTRVRNIGIIAHVDHGKTTTSDTLLAASGIISQKVAGEALALDYLSVEQQRGITVKAANISLYHEIDGKGYVINLIDTPGHVDFSGRVTRSLRVLDGSIVVIDAVEGIMTQTETVLRQSLEERVRPILFINKVDRLIKELKLSSQEIQKRLIDLIIEVNNLIETYGEPEFKDQWKIKPELGNVVFGSAKDKWGFSVPMAGKRGVKFSDVVNAYTSGDKAKIEELASKVPIHEALLDAVIKFVPNPRDSQKYRIPKIWKGDLDSEIAKAMINADPNGPIVMMINDMKVDPHAGLVATGRVFSGTLRAGEEVWLVNAKRQQRILQVSLYMGAIRELAEEIPVGNIAAALGMDAARSGETGVDIRFKDSVLGSFEKLHYISEPVVTISVEPRNPKDLTKMIDALRKLSIEDSNLVVKINEETGEYLLSGMGFLHLEVSLQLLKENYGLDVVTTPPIVVYRESIRNKSQVFEGKSPNKHNKLYISVEPLNNQTIDLIANGTIKEDMDNKEMAKILRDQAEWDYDEAKKIVAIDENINVFIDATSGVQHLREIMDTLLQGFRLAMKEGPLAFEPVRGVKVVLHDAVVHEDPAHRGPAQLYPAVRNAIFAGILTSKPTLLEPLQKLDIRIPMEYLGNVTAVITRKRGKVINVVQTGNVARVYAEIPVGESFELASELRASSAGRAFWGTEFSRWAPVPDSILVDLIMKIRERKGKPKQLPKVEDFIS", "output": "Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)."}]}
+{"id": "function_test_2647", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSQNSLRLVEDKSVDKSKALEAALSQIERSFGKGSIMKLGSNENVIEIETISTGSLGLDIALGVGGLPKGRIIEIYGPESSGKTTLALQTIAESQKKGGICAFVDAEHALDPVYARKLGVDLQNLLISQPDTGEQALEITDTLVRSGAVDVLVVDSVAALTPRAEIEGEMGDSLPGLQARLMSQALRKLTASISKSNTMVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRRIGSVKEREEVIGNQTRVKVVKNKMAPPFKQVEFDIMYGEGVSKTGELVDLGVKAGIVEKSGAWFSYNSQRLGQGGENAKTFLRDNPDLAREIELALRENAGLIADRFLQNGGPDADDGDGADM", "output": "Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage."}]}
+{"id": "function_test_2648", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "STVVGKCCKGNFGMSRFLLSNDFQRKLIVSGKESYYDHFSKRSYSSPSKAPGTESTITSTKIKMPNIGSEGFAFSSFLSTVNKNSRMINFSSCLKTPVKPEQIAANPVILKMTTELEKIPRALRWMCGGFPAIALCDAPEPWQLGFQDAATPIMQGIMDLHHDIFFFLVQILVFVLWVLSRALWCFRSKISPIPQRIVHGTTIEILWTILPSIILMFIAIPSFTLLYSMDDVVVDPAITIKAIGHQWYWSYEYSDYNNSDEQSLAFDSYMVPEDDLELGQLRLLEVDNRVVVPAKTHLRVLITSADVLHSWAVPSLGVKCDAVPGRLNQISTFIQREGVYYGQCSEICGTNHAFMPIVVEAVSTKDYGSWVSNQIQ", "output": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix."}]}
+{"id": "function_test_2649", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MALSASLHLRQSQSLVMTPQLMQSIQLLQMNHLELTQFIAQEIEKNPLLEVQSPSDEASTAERGDSGPQPEEAGSEIDEGAGEGDVYDSATSRSGERLSDGLDSDFANVFPDDTTPQRADAPELLGQWKSMPGASDGESYDLDDFVASRKTLREALIEQLPFALESGSHRLIAQYLIDQLDDAGYLHADLAETAQRLASASEDVTRVLDVLQQFDPPGVFARTLGECLGLQLRARNRLDPAMEALVGNLDLLARRDFASLKKICGVDEEDLIDMFAEIRKLDPKPGTSFETGSFETIIPDAVVRTAPDGGWLVELNPDALPRVLVNHEYFAEISRSCRKSSGEQIFLNECLQNANWLTRSLDQRARTIMKVASEIVRQQDAFLMHGVGHLRPLNLRTVADAIKMHESTVSRVTSNKYMLTPRGLYELKYFFTASIGSAENGDAHSAESVRHRIRTMVNQESADAVLSDDDIVDILKKAGVDIARRTVAKYREAMHIPSCVQRRREKRALARVG", "output": "Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of the nitrogen fixation genes (nif operon), glnA and dctA for dicarboxylate transport. The open complex (sigma-54 and core RNA polymerase) serves as the receptor for receipt of the melting signal from the remotely bound activator proteins NifA, NtrC, or DctD for the expression of the regulated proteins."}]}
+{"id": "function_test_2650", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSSAPAAGTASTSRFFKSHVSETDPDIFSAIQKEFGRQQHEIELIASENIVSQAVLDAAGSVLTNKYAEGYPGKRYYGGCQYVDIVEDIAIDRAKKLFNCEFANVQPNSGSQANQGVFNALAQPGDTILGLSLAAGGHLTHGAPVNQSGKWFKAVHYMVKPDSHLIDMDEVRKLAQEHKPRIIIAGGSAYPRKIDFAAFRAIADEVGAIFLVDMAHFAGLVAAGLIPSPFPHAHVVTTTTHKTLRGPRGGMILTNDADIAKKINSAIFPGIQGGPLMHVIAGKAVAFGEALRPDFKVYIKQVMDNARALGEVLVQNGFALVSGGTDTHLVLVDLRPKKLTGTKAEKALGRANITCNKNGIPFDPEKPMVTSGIRLGSPAGTTRGFGVAEFQEIGRLISEVLDGVAKNGEDGNGAVEAAVKAKAIALCDRFPIYA", "output": "Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism."}]}
+{"id": "function_test_2651", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MADDPSAADRNVEIWKIKKLIKSLEAARGNGTSMISLIIPPKDQISRVAKMLADEFGTASNIKSRVNRLSVLGAITSVQQRLKLYNKVPPNGLVVYCGTIVTEEGKEKKVNIDFEPFKPINTSLYLCDNKFHTEALTALLSDDSKFGFIVIDGSGALFGTLQGNTREVLHKFTVDLPKKHGRGGQSALRFARLRMEKRHNYVRKVAETAVQLFISGDKVNVAGLVLAGSADFKTELSQSDMFDQRLQSKVLKLVDISYGGENGFNQAIELSTEVLSNVKFIQEKKLIGRYFDEISQDTGKYCFGVEDTLKALEMGAVEILIVYENLDTMRYVLRCNGSEEEKTLYLTPEQEKDKSHFIDKETGQEHELIESMPLLEWFANSYKKFGATLEIVTDKSQEGSQFVKGFGGIGGILRYRVDFQGMDYQGVDDEFFDLDDY", "output": "Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA . Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (By similarity). Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular genes."}]}
+{"id": "function_test_2652", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAQQADQQTVTDSTPELPTTIKELADLLDIPLVDCLVPCNFCGKFLDFLEVCDFDKKQLTLIWKGHFVTACCRSCCAATAIYEFNEFYQQTVLGRDIELATGKSIFDLKIRCQTCLSFLDTIEKLDSCGRGLPFHKVRDRWKGICRQCKHLYLNNDR", "output": "Plays a major role in the induction and maintenance of cellular transformation. E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity. Protects host keratinocytes from apoptosis by mediating the degradation of host BAK1. May also inhibit host immune response."}]}
+{"id": "function_test_2653", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQLVLAAKYIGAAIATIGLLGAGIGIAIVFAALINGTSRNPSLRNTLFPFAILGFALSEATGLFCLMISFLLLYGV", "output": "Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element."}]}
+{"id": "function_test_2654", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKKQNLVSFSDNLEAMRKFSETYAKRTGTFFCADNSVTAVVIEGLARHKDKYGAPLCPCRHYEDKKAEISATYWNCPCVPMRERKECHCMLFLTPDNEFTSDLQEIDKTTLLEKIASS", "output": "Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin."}]}
+{"id": "function_test_2655", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTDDNIRQIAFYGKGGIGKSTTSQNTLAAMAEMGQRILIVGCDPKADSTRLMLHSKAQTTVLHLAAERGAVEDI", "output": "The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein."}]}
+{"id": "function_test_2656", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MVDIIFNSSFLGDMGDHSKKKSGIAMCVGCGSQIHDQYILRVAPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRLFGIKCANCNIGFCSSDLVMRARDNVYHMECFRCSVCSRHLLPGDEFSLRDEELLCRADHGLLMEQASAGSPLSPGIIHSRSLHIADPVSVRQPPHRNHVHKQSEKTTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIFMKQLQQQHHSDKTNLQGLTGTPLVAGSPIRHDNTVQGNPVEVQTYQPPWKALSEFALQSDLDQPAFQQLVSFSESGSMGNSSGSDVTSLSSQLPDTPNSMVASPVDT", "output": "Binds to one of the cis-acting domain of the insulin gene enhancer. May be involved in subtype specialization of primary motoneurons."}]}
+{"id": "function_test_2657", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MHPMLTIAVRAARKAGNVIAKNYETPDAVEASQKGSNDFVTNVDKAAEAVIIDTIRKSYPQHTIITEESGEHVGTDQDVQWVIDPLDGTTNFIKRLPHFAVSIAVRIKGRTEVAVVYDPMRNELFTATRGQGAQLNGYRLRGSTARDLDGTILATGFPFKAKQYATTYINIIGKLFTECADFRRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGELLVREAGGIVSDFTGGHNYMMTGNIVAGNPRVVKAMLANMRDELSDALKR", "output": "Part of the processive rRNA transcription and antitermination complex (rrnTAC). The complex forms an RNA-chaperone ring around the RNA exit tunnel of RNA polymerase (RNAP). It supports rapid transcription and antitermination of rRNA operons, cotranscriptional rRNA folding, and annealing of distal rRNA regions to allow correct ribosome biogenesis. This subunit may play a central role in organizing the structure."}]}
+{"id": "function_test_2658", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIHDMIKTIEHFAETQADFPVYDILGEVHTYGQLKVDSDSLAAHIDSLGLVEKSPVLVFGGQEYEMLATFVALTKSGHAYIPVDQHSALDRIQAIMTVAQPSLIISIGEFPLEVDNVPILDVSQVSAIFEEKTPYEVTHSVKGDDNYYIIFTSGTTGLPKGVQISHDNLLSFTNWMISDDEFSVPERPQMLAQPPYSFDLSVMYWAPTLAMGGTLFALPKTVVNDFKKLFATINELPIQVWTSTPSFADMALLSNDFNSETLPQLTHFYFDGEELTVKTAQKLRQRFPKARIVNAYGPTEATVALSAVAITDEMLETCKRLPIGYTKDDSPTYVIDEEGHKLPNGEQGEIIIAGPAVSKGYLNNPEKTAEAFFQFEGLPAYHTGDLGSMTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSQYVKSAVAVPRYNKDHKVQNLLAYIVLKEGVRDDFERDLDLTKAIKEDLKDIMMDYMMPSKFIYREDLPLTPNGKIDIKGLMSEVNK", "output": "Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall."}]}
+{"id": "function_test_2659", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIIYRDLISHDEMFSDIYKIREIADGLCLEVEGKMVSRTEGNIDDSLIGGNASAEGPEGEGTESTVITGVDIVMNHHLQETSFTKEAYKKYIKDYMKSIKGKLEEQRPERVKPFMTGAAEQIKHILANFKNYQFFIGENMNPDGMVALLDYREDGVTPYMIFFKDGLEMEKC", "output": "Involved in calcium binding and microtubule stabilization (By similarity). Acts as a negative regulator of TSC22D1-mediated apoptosis, via interaction with and destabilization of TSC22D1 protein (By similarity)."}]}
+{"id": "function_test_2660", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEEEIAALVIDNGSGMCKAGFGRDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVMDSGDGVTHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAEREIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFRCPEALFQPSFLGMESCGIHETTFNSIMKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "output": "Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells."}]}
+{"id": "function_test_2661", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MADQLTPHLEIPTAIKPRDGRFGSGPSKVRLEQLQTLTTTAAALFGTSHRQAPVKNLVGRVRSGLAELFSLPDGYEVILGNGGATAFWDAAAFGLIDKRSLHLTYGEFSAKFASAVSKNPFVGEPIIITSDPGSAPEPQTDPSVDVIAWAHNETSTGVAVAVRRPEGSDDALVVIDATSGAGGLPVDIAETDAYYFAPQKNFASDGGLWLAIMSPAALSRIEAIAATGRWVPDFLSLPIAVENSLKNQTYNTPAIATLALLAEQIDWLVGNGGLDWAVKRTADSSQRLYSWAQERPYTTPFVTDPGLRSQVVGTIDFVDDVDAGTVAKILRANGIVDTEPYRKLGRNQLRVAMFPAVEPDDVSALTECVDWVVERL", "output": "Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine."}]}
+{"id": "function_test_2662", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MVHFTAEEKAAITSLWGKMNVEEAGGEALGRLLVVYPWTQRFFDNFGNLSSPSAILGNPKVKAHGKKVLTSFGDAIKNMDNLKTTFAKLSELHCDKLHVDPENFRLLGNVMVIILATHFGKEFTPEVQAAWQKLVSAVAIALGHKYH", "output": "The epsilon chain is a beta-type chain of early mammalian embryonic hemoglobin."}]}
+{"id": "function_test_2663", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDYQVSSPTYDIDYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNILVVLILINCKRLKSMTDIYLLNLAISDLLFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYLAIVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQREGLHYTCSSHFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL", "output": "Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor."}]}
+{"id": "function_test_2664", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MASQGTKRSYEQMETDGERQNATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTVERMVLSAFDERRNRYLEEHPSAGKDPKKTGGPIYKRVGGRWMRELVLYDKEEIRRIWRQANNGDDATRGLTHMMIWHSNLNDTTYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGIGTMVMELIRMIKRGINDRNFWRGENGRKTRSAYERMCNILKGKFQTAAQRAMMDQVRESRNPGNAEIEDLIFSARSALILRGSVAHKSCLPACVYGPAVSSGYDFEKEGYSLVGIDPFKLLQNSQVYSLIRPNENPAHKSQLVWMACHSAAFEDLRLLSFIRGTKVSPRGKLSTRGVQIASNENMDNMESSTLELRSRYWAIRTRSGGNTNQQRASAGQISVQPTFSVQRNLPFEKSTVMAAFTGNTEGRTSDMRAEIIRMMEGAKPEEVSFRGRGVFELSDEKATNPIVPSFDMSNEGSYFFGDNAEEYDN", "output": "Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway. Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus."}]}
+{"id": "function_test_2665", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTIALGKFTKDENDLFDIMDDWLRRDRFVFVGWSGLLLFPCAYFAVGGWFTGTTFVTSWYTHGLASSYLEGCNFLTAAVSTPANSLAHSLLLLWGPEAQGDFTRWCQLGGLWTFVALHGAFGLIGFMLRQFELARSVQLRPYNAIAFSGPIAVFVSVFLIYPLGQSGWFFAPSFGVAAIFRFILFFQGFHNWTLNPFHMMGVAGVLGAALLCAIHGATVENTLFEDGDGANTFRAFNPTQAEETYSMVTANRFWSQIFGVAFSNKRWLHFFMLFVPVTGLWMSALGVVGLALNLRAYDFVSQEIRAAEDPEFETFYTKNILLNEGIRAWMAAQDQPHENLIFPEEVLPRGNAL", "output": "Photosystem II (PSII) is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. The D1/D2 (PsbA/PsbA) reaction center heterodimer binds P680, the primary electron donor of PSII as well as several subsequent electron acceptors. D2 is needed for assembly of a stable PSII complex."}]}
+{"id": "function_test_2666", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSRFVQDLSKAMSQDGASQFQEVIRQELELSVKKELEKILTTAPSHEFEHTKKDLDGFRKLFHRFLQEKGPSVDWGKIQRPPEDSIQPYEKIKARGLPDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIYTFNQSRYPRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIGEGKEYIFVSNIDNLGATVDLYILNHLMNPPNGRPCEFVMEATNKARADVKGGTLTQYEGKLRLVEIAQVPKPHVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNPKTLDGGLNVIQLETAVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGSSFTKVQDYLRRFESIPDMLELDHLTVSGDVTFGKNVSLKGTVIIIXNHGDRIDIPPGAVLENKIVSGNLRILDH", "output": "UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen."}]}
+{"id": "function_test_2667", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIGIVLVLASLLSVGGQLCQKQATRPLTTGGRRRHLMLWLGLALICMGAAMVLWLLVLQTLPVGIAYPMLSLNFVWVTLAAWKIWHEQVLPRHWLGVALIISGIIILGSAA", "output": "Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane."}]}
+{"id": "function_test_2668", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "RVCYAIPLPICY", "output": "Antibacterial activity against B.subtilis, E.coli, S.aureus, M.luteus and P.putida. Antifungal activity against S.cerevisiae."}]}
+{"id": "function_test_2669", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "SDPKIGDGCFGLPLDHIGSVSGLGCNRPVQNRPKK", "output": "Exhibits vasoactive  and hypotensive activity (By similarity). Is only weakly active on natriuretic peptide receptor-C (NPR3)."}]}
+{"id": "function_test_2670", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "VSSVISSSLFEKMLLHRGFYTYDAFIAAAKSFPAFATTGSTDVRKREVAAFLAQTSHETTGGWPTAPDGPYELGSTSDYFGRGPIQISYNYNYGAAGKAIGVDLLRNPDLVTSDNTVEFKTALWFWMTPQSPKPSSHDVITGRWSPSSTDKAAGRVPGYGVLTNIIDGGVECGKGQESHVADRIGYYKDNLDCYNQKPFA", "output": "This protein functions as a defense against chitin-containing fungal pathogens."}]}
+{"id": "function_test_2671", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "ASAAGAVRAGDDETLLNPVLNSLDNLVSGL", "output": "Lacks antimicrobial activity. Does not inhibit the formation of NO by neuronal nitric oxide."}]}
+{"id": "function_test_2672", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEVADPSRAPPEYKDVAWIADTCKLLMGIGWTTNYVGMIYKSLKDETYAMALMALCCNFAWELTYALIYPFGSDLEMYVHFSGLMLNCGVMYTAVKNAHREWGHSPLVLRNLPLIFIICVSGFMSGHVALAAQVGPSLAQAWSAYGCQLLLSVGGLCQLLCRGHSRGASYFLWFSRFFGSLVLVPQDILRYKYWRVDHEYMGSPLYIWFVCIFLLLDGSYGICLWYVRRFERQTAVAHKKKK", "output": "Terpene cyclase; part of the gene cluster that mediates the biosynthesis of diterpenoid pyrones . The first step of the pathway is the synthesis of the alpha-pyrone moiety by the polyketide synthase dpfgA via condensation of one acetyl-CoA starter unit with 3 malonyl-CoA units and 2 methylations (Probable). The alpha-pyrone is then combined with geranylgeranyl pyrophosphate (GGPP) formed by the GGPP synthase dpfgD through the action of the prenyltransferase dpfgC to yield a linear alpha-pyrone diterpenoid (Probable). Subsequent steps in the diterpenoid pyrone biosynthetic pathway involve the decalin core formation, which is initiated by the epoxidation of the C10-C11 olefin by the FAD-dependent oxidoreductase dpfgE, and is followed by a cyclization cascade catalyzed by the terpene cyclase dpfgB (Probable). The short chain dehydrogenase/reductase dpfgG then oxidizes the 8S hydroxy group to a ketone and the short chain dehydrogenase/reductase dpfgH reduces the ketone to the 8R hydroxy group to yield higginsianin B . Higginsianin B is further methylated by the methyltransferase dpfgI to produce the intermediate named FDDP B . The cytochrome P450 monooxygenase dfgpJ then catalyzes a three-step oxidation at C-27 to generate a carboxylic acid as well as C-26 hydroxylation . Finally, methyltransferase dpfgK methylates the carboxylic acid generated by dpfgJ, yielding the final diterpenoid pyrones from the pathway which were named FDDP D and FDDP E ."}]}
+{"id": "function_test_2673", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAEESRGQRGSGYGLGLSTRTQVTGYQFLARRTAMALTRWRVRMEIEPGRRQTLAVVASVSAALVICLGALLWSFISPSGQLNESPIIADRDSGALYVRVGDRLYPALNLASARLITGRPDNPHLVRSSQIATMPRGPLVGIPGAPSSFSPKSPPASSWLVCDTVATSSSIGSLQGVTVTVIDGTPDLTGHRQILSGSDAVVLRYGGDAWVIREGRRSRIEPTNRAVLLPLGLTPEQVSQARPMSRALFDALPVGPELLVPEVPNAGGPATFPGAPGPIGTVIVTPQISGPQQYSLVLGDGVQTLPPLVAQILQNAGSAGNTKPLTVEPSTLAKMPVVNRLDLSAYPDNPLEVVDIREHPSTCWWWERTAGENRARVRVVSGPTIPVAATEMNKVVSLVKADTSGRQADQVYFGPDHANFVAVTGNNPGAQTSESLWWVTDAGARFGVEDSKEARDALGLTLTPSLAPWVALRLLPQGPTLSRADALVEHDTLPMDMTPAELVVPK", "output": "An ATPase (shown for residues 80-506) . Part of the ESX-5 specialized secretion system, which is responsible for the secretion of EsxN and a number of PE_PGRS and PPE proteins, including PPE41."}]}
+{"id": "function_test_2674", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MALQTGEPRTLAEKIWDDHIVVSGGGCAPDLIYIDLHLVHEVTSPQAFDGLRLAGRRVRRPELTLATEDHNVPTVDIDQPIADPVSRTQVETLRRNCAEFGIRLHSMGDIEQGIVHVVGPQLGLTQPGMTIVCGDSHTSTHGAFGALAMGIGTSEVEHVLATQTLPLRPFKTMAVNVDGRLPDGVSAKDIILALIAKIGTGGGQGHVIEYRGSAIESLSMEGRMTICNMSIEAGARAGMVAPDETTYAFLRGRPHAPTGAQWDTALVYWQRLRTDVGAVFDTEVYLDAASLSPFVTWGTNPGQGVPLAAAVPDPQLMTDDAERQAAEKALAYMDLRPGTAMRDIAVDAVFVGSCTNGRIEDLRVVAEVLRGRKVADGVRMLIVPGSMRVRAQAEAEGLGEIFTDAGAQWRQAGCSMCLGMNPDQLASGERCAATSNRNFEGRQGAGGRTHLVSPAVAAATAVRGTLSSPADLN", "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."}]}
+{"id": "function_test_2675", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MYGIEYTTTLIFLILFVLLNYILKSITRVMDYILYRFLLFIVIVTPFVNSQNYGINLPITGSMDTNYQNVSTSKPFLTSTLCLYYPTEAETEIADSSWKDTLSQLFLTKGWPTGSVYLKSYTDIATFSINPQLYCDYNIVLMKYNANAELDMSELAALILNEWLCNPMDITLYYYQQTDEANKWISMGDSCTIKVCPLNTQTLGIGCLTTDTTTFEEVATAEKLAITDVVDGVNYKINVTTATCTIRNCKKLGPRENVAVIQVGGSNILDITADPTTAPQTERMMRVNWKKWWQVFYTIVDYVNQIIQAMSKRSRSLDSAAFYYRI", "output": "Calcium-binding protein that interacts with rotavirus cell receptors once the initial attachment by VP4 has been achieved. Rotavirus attachment and entry into the host cell probably involves multiple sequential contacts between the outer capsid proteins VP4 and VP7, and the cell receptors. Following entry into the host cell, low intracellular or intravesicular Ca(2+) concentration probably causes the calcium-stabilized VP7 trimers to dissociate from the virion. This step is probably necessary for the membrane-disrupting entry step and the release of VP4, which is locked onto the virion by VP7."}]}
+{"id": "function_test_2676", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTENALLLLNLGSPDSTRVEDVRRYLDQFLMDPYVVDLPWPLRRLLVSLILIKRPAESAHAYSSIWWDEGSPLIVLSRRLQEAMKPHWPHGPVELAMRYGQPAIEKVLLDLARRGIRRVTLAPLYPQFADSTTTTAEQEVRRVIAAHRLELEVSTLPPFYDQPVYLDALVESVRPYLQQPHDHLLLSFHGLPERHIRKLVKDPAHDLLAENSRNVSPEALALCYRSQCLRTAEAFAERAGLEQGRWSVSFQSRLGRAKWIEPYTDAKLDELVQRGVKRLLVMCPAFVADCIETLEEIGMRGREQFISAGGEDLVLIPCLNDHPAWVGALGEMSGRLARPL", "output": "Catalyzes the ferrous insertion into protoporphyrin IX."}]}
+{"id": "function_test_2677", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTLKTIEGTFIAPKGRYALVVGRFNSFVVESLVSGAVDALVRHGVAESEITIIRAPGAFEIPLVTQKVAQQGGFDAIIALGAVIRGGTPHFEYVAGECTKGLAQVSLQFGIPVAFGVLTVDSIEQAIERSGTKAGNKGAEAALSALEMVSLLAQLEAK", "output": "Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin."}]}
+{"id": "function_test_2678", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKVIKTLSIINFFIFVTFNIKNESKYSNTFINNAYNMSIRRSMEESKPPTGAVAGSGAGAGSGAGAVAGSGAGAVAGSGAGAVAGSGAGAVAGSGAGAVAGSGAVAGSGAGNGANPGADAERGPSTPATTTTTTTTNDAEASTSTSSENRNHNNAETNPKGKGEVQKPNQANKETQNNSNVQQDSQTKSNVPRTQDADTKSPTAQPEQAENSAPTAEQTESPELQSAPENKGTGQHGHMHGSRNNHPQNTSDSQKECTDGNKENCGAATSLLNNSSNIASINKFVVLISATLVLSFAIFI", "output": "May play a role in the merozoite attachment to the erythrocyte."}]}
+{"id": "function_test_2679", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKRIGIMTSGGDAPGMNLAIRAVARKALSSGLEAYGINYGFAGLVAGDIHEFKAADLDDMVSQGGTMLYSARYPEFAQEESQLKGIEQLKKFGIDALVVIGGDGSYHGALRLTEHGYNTIGLPGTIDNDIPFTDFTIGFDTALNTAVDAIDKIRDTAKSHQRVFAVQVMGRNAADIALWAGVASGADAVIAPGFDYDVEAIANKLKKNRANGKDYGIIVIAEGDANSDAAPEFIDQLKQYGDFDARATVIGHVQRGGVPSAKDRVLASKMGAYAVELLLEGKGGLAVGILENKVQAHNMLDLFDAKHQADDSLYQLSEDLSF", "output": "Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis."}]}
+{"id": "function_test_2680", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNQKVLQTLEYDKIKSQLSDFLSTPIGRQEADALQPITDVHIINYWLQETADAMMIDRLKGGIPLAKLADITPHLKRLNIQASLSATELAEIGNVLRNTSAISNFFIQMKDESIGESLEVLIEQAEQLETLPEVTKSIQTAIDSTGRINDEASYELKSVRGKIVGHENAIKNKMQEFTKGKTAQYLSDPIVTIRSDRYVLPVKAEYRSQFGGVVHDQSQTGLTLYIEPQAVVELSNKLSELRVKESAEEQRVLQELSAELEPHTNEIQQNVQILGHFDFVNAKARLAARLDAMQPTVSVENHISLRQAWHPLLDKKIAVANDISLGDSYKTIIITGPNTGGKTITIKTLGLLQLMAQSGLFITTRQPSTIGIFDEVFADIGDEQSIEQNLSTFSSHMANIVSMLDHIDDKTLVIFDELGAGTDPAEGAALAIAILDKVASLGAYTIATTHYPELKLYGYNRPETKNASMVFDVETLQPTYQFLMGVPGQSNALAIAKRLGFGEDVIGAAMALTDESDQDLNNMIADLVAQRDEVKKNNEELRSQLKATEEKSEALSEEQSKLEKERAHVILDAKNEANHIVAATKKQAEQLISEIRKERLRAGQRGELTEQELQARKGKLDQLRQNDSLEKNKILQKAKKVKELAPGDEITVRSYSQQGTLVKKHKNGQWEVEMGILKMLVDEDDIVKTEATVKAQKGKAKKKQQKIIRKTTSSGSTRASVKSSLDLRGVRYEAALTELDRYLDTAVLANISPVEIIHGKGTGALRQGVTEFLRSDRRVKSYHFASANAGGDGATIVELK", "output": "Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity."}]}
+{"id": "function_test_2681", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNIHEYQAKAVLQPFGVSLSKGVAILKASEAEAAAKQLPGPVWVVKSQIHAGGRGKGKFKEASAGSQGGVRLAKSIDEVKQFAQEMLGATLVTLQTGPAGKQVNRLYIEEGSAIDKEFYLSLLVDRATSRVSFVVSTEGGMNIEDVAHDTPEKIISFSVDPATGIMPHHGRIVAKTLGLTGELAKQAGKLTTQLYTAFVAKDMEMLEINPLVLTKDGELRCLDAKMSFDSNSLYRQPDVVALRDTTEEDAKEIEASKHELAYIALEGTIGCMVNGAGLAMATLDIIKLYGESPANFLDVGGGATEEKVTAAFKIITADPNVKGILVNIFGGIMKCDVIARGVIAAVKTVGLEVPLVVRLEGTNVEEGKAIIRDSGLNVLSADDLDDAAQKIVNAVKKAA", "output": "Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit."}]}
+{"id": "function_test_2682", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQKPKYKRIVLKLSGEALAGHNTYGIDNEVLNSIARQVVEVVRQEVQVAIVVGGGNIWRGVAGSAKGMDRATADYMGMLATVINALALQDALEQEGMGTRVMSAIEMKEVCEPYIRRRAIRHLEKGRVTIFAAGTGNPYFSTDTAAALRSAEIEAEVILMAKKVDGVYDADPVKNPAALKFDRLNYIDVLSRGLGVMDSTAASLCMDNGIPIIVFDLTREGNILKAVLGEEIGTYVGR", "output": "Catalyzes the reversible phosphorylation of UMP to UDP."}]}
+{"id": "function_test_2683", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSIEQVREYANQILGMQLVTHQTGPEGQKVNRLMIEEGADIKQELYVSLVVDRISQKIVLMGSSEGGMDIEEVAEKHPELIHKVIVEPSTGLLDAQADDLAAKIGVPAASIPQARAILQGLYKAFWETDASLAEINPLNVSGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDPAEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPDLKAILVNIFGGIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLADSGLPIISADSMEEAAQKVVAAAAGK", "output": "Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit."}]}
+{"id": "function_test_2684", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSIEVDWKTATSGPDGEALAERIRSFIHDKFQQVALPRFIRSVQVHSFDFGTVPPDLEIKDFCEPFADFYEEDEDDETSEVSEELVSAHGNQWHRTHSELNEPPYRDEVTMNQPLRDPFDEGFHPSPLRSPMEHLNPHFLPRAGTPGIPGGTSTIGYHLMSLGGLSGTQTPLAAVAGGTPFANGWTDHNLGPGNRGHASGPAAGAMRQHRPEDIDSSNPTSRPSTSSTLPSHPSGSNRNSGDGSHPEEEHLDDPAEPDHPFRFPKMRERRPEDFQVMCRAKYAGDVRLSLTAEILLDYPMPSFVGLPLKLNITGVTFDGVAVVAYIRKRVNFCFLSAEDADALIGADDQETRDKDDHPRSGLDPTTSPKRQGGLLREIRVESEIGRKEDGKQVLKNVGKVERFVLAQVRRIFEEELVFPSFWTFLI", "output": "Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm12 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10. The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The mdm10-mdm12-mmm1 subcomplex further acts in the TOM40-specific pathway after the action of the mdm12-mmm1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids."}]}
+{"id": "function_test_2685", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSFVAHPNIDPKSLGKVGVLLGGRSAEREISLMSGNGVLAALQSRGVDAHGFDPGLQSVAELAAAGFDRVFIALHGRYGEDGTIQGLLEQLGVPYTGSGVLASAMAMDKQATKRLWMTYGLATPRFAMLHADTDFDAVAADLGLPLIVKPAREGSSIGLTKVTAADQMRAAFEKAAALDNDVIAETFIDGAELTCPIVGEGDSAEALPVIRIVAPEANYDYQNKYFTDDTQYLCPSGLDPEVEREVRALAVQSYRVLGCRGWARADLMLRADGKPFLLEMNTSPGMTGHSLVPMAARAVGISYEDFVMQVVAAATLDLHPNEHWKPE", "output": "Cell wall formation."}]}
+{"id": "function_test_2686", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLGRVTGKVLAYIALTKPRVIELLLVATIPAMLLADRGNVDIALILSTLFGGWMGAASANSLNCVVDADIDKVMKRTARRPLARDAVPTSHAFVFGMTLGVASFLWLWWRANLLAGCLVVLTIAFYVLVYTMVLKRRTWQNVVWGGAAGCMPVMVGWSAVTGSLSWQPIVLFLVIFFWTPPHTWALAMRYKEDYKAAGVPMLPVIATEEHVTKQILLYSWAMVITSLTLVPAAGVVYAAVTLVAGAWFLLMAHQLYRSVRGGAAVKPLRLFLQSNNYLAVVFVGLAVDSVLGLQTVGSLLS", "output": "Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group."}]}
+{"id": "function_test_2687", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTLDKLRKKYIDFFKSKKHFEIMGKSLVPENDPTVLFNTAGMQPLIPYLLGEVHPSGDMLVNVQKCLRTGDIDEVGDLSHLTFFEMLGNWSLGAYFKEYSVKCSFEFLTSSEYLNIPKDRLYVSVFEGDQEIPRDTETAKVWESLGIPKDRIYYLSKDHNFWGPVGSKGPCGPDTEIYVDTGKIKCSINCNVTCSCGKYFEIWNNVFMQYNKDENGNYMELDRKCVDTGMGLERTIAFLQGKSSVYDTDAFMPIIKRIEFISGKIYGQKEDDDRCIRIISDHIKAACFILADSSGVFPSNLGQGYVLRRLIRRSIRYAKKLGIKSHFLADLVDSVETIYRSFYNELTEKKDFIKKELSTEEEKFFKTLFQGEQEFIKITRNLSSKTIPGDIAFKLYDTYGFPYELTEELAFEYGFDIDKSGFNEYFKKHQKTSKKGGDKVFKGGLADYTYETTKLHTATHLLHKALQLVLGDHVKQKGSNITAERLRFDFVHSKKMTDDEIKKVEDIVNLQIKNSLSVKKSIMELSEAREKGAMALFGEKYDNLVSVYEIDGFSLEVCGGPHVENTNELGTFKIQKEQSSSSGIRRIKAILIDE", "output": "Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)."}]}
+{"id": "function_test_2688", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPELPEVEAIRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRLSDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVDLVMSNGKVLRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMDNKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLKDFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQK", "output": "Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates."}]}
+{"id": "function_test_2689", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MYVIQINKATKTYNNGTIAVHPTSLNFEPGTFNAILGPSGAGKSTLLRMINGLEIPTTGEIIIQGQTLTAKNLRQVRSRTAMVFQQFNLVGRLNVMTNILTGRLYYIPWWSSILYMFGQRDWKIAQWALNRVSLKEKAWERVDRLSGGQQQRVGVARALAQRPEVILADEPVASLDPIASEEIMELLREICRQDGITIVANLHQVSLALRYADRVIGLNKGRVVFDDSPQALSNNKNTLRTIYQREDGSVDDTLEMAVTD", "output": "Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system."}]}
+{"id": "function_test_2690", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAKLTLEVEQYTQNLREKLQEAGYSYYVLDQPIMEDAVYDHLLRELQELESQYPQLIVSDSPTQRVGEKPATKFVSVKHNIPLYSLENAFNIQELKSWQERWQRQTLLENQRLTLPLRGEVKIKNSIDESDNFSTVNSLAPVITGSNFDEIDLASVDYICELKIDGSALALTYENGLLVRGATRGDGIMGEDITQNVKTINSIPLKLKVDNPPLLVEVRGEAFLSINVFENINAEREKIGEIIFANPRNAAAGTLRQLDSKIVAKRRLDFFAYTLYLEENESNFLQFYTQSQCLELLKKLGFKVNPNGQVCSSLNEVEAYYQYWDKQRENLPYLTDGVVVKLNSLSLQEKLGFTQKYPRWAIALKYPAEEIPTIVQGVTVQVGRTGAITPVAELKPVQLAGTTVQRASLHNSDRLAELDLHIGDTVIVRKAGEIIPEVVRVLPELRPKKAQRFQMPTHCPECSQPLIKPRNEAVTRCINTSCPAILRGSLAHWASRAALDINGLGEKLVQQLVNSGLVKSVADLYNLTMEDLTSLERMGKKSANKLIEAMGTSKAQPWRRVLYGLGIRHVGTVNAELLTQKFPTVAQLSQAKATDIETVHGIGPEIAQYVEQWFRVPANQNLVERLKIAGVTMETKDSTSGMAKLTETVLAIQNLAARQNLVARQNLENLVERLKIAGVTMETKDSTSDVVEVQSGLLRGKTFVLTGTLPTMRRDEAKNLIQNAGGKVTSSVSSKTDFIVVGEDGGSKLEKAKKLGVKELSESELLEALAVTGI", "output": "DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA."}]}
+{"id": "function_test_2691", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTTFGTPLSPHATKVMLLGSGELGKEVLIALQRLGVETIATDRYDNAPGQQVAHHARTITMSDPAQLKSLIEKERPHLVVPEIEAIATAMLEELEAAGTVRVIPTARAARLTMDREGIRRLAAETLGLPTSPYVFCDSLQELQAAIDTNIGYPCIVKPVMSSSGKGQSKIAGPADVKTAWDYAMAGGRVSHGRVIVEGFIDFDYEITQLTVRALGADGQVETHFCEPIGHIQVSGDYVESWQPHPMREAALQKSRAIAKAVTDDLGGQGLFGVELFVKGDEVWFSEVSPRPHDTGMVTMCTQWQNEFELHARAILGLPVNTALKSSGASAVIYGGVDAKGIVFDGVADALRVPNTDIRLFGKPESFVKRRMGVALAFDADVEVARANAKLAASRVKPRVAKG", "output": "Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate."}]}
+{"id": "function_test_2692", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRVGLYPGTFDPITLGHLDIIRRASALLDKLVIGVAINRDKGPLFCLEERVAMVEAESIKIAAMTGLEIVTHPFENLLIDCARDVGATVIVRGLRAVADFEYEYQMVGMNRQLDDTIETVFLMAEAEHQAIASKLVKEIARLGGDIEKFVTPEVNAALLNKIGRAG", "output": "Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate."}]}
+{"id": "function_test_2693", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGNCADCLRGFFCPPKNTNIRISLPAVCFVWQIAMIVLFGVFIRYDAESDIRLWLQLKHTNNITSDIENDFYFRYPSFQDVHVMIFVGFGFLMTFLKRYSFGGVGFNFLIGAFGLQWALLMQGWFHALDPTTGKISIGVEGLINADFCVAASLIAYGALLGKVSPVQLMVVTLFGVTLFAVEEYIILNLLHCRDAGGSMVIHCFGGYYGLTISWILYRPKLHQSKRLNGSVYHSDVFAMIGTLFLWMFWPSFNSAITDHGSGQHRTAINTYIALASSVLTTVAISSASEKRGKLDMVHIQNATLAGGVAMGTAAEFMITPYGALIVGFCTGIISTFGYLFVSPFMEKYLKIQDTCGVHNLHAMPGMLGGFIGAIVAAAATEEVYSREGLIETFDFEGKFADRTVGTQGGFQAAGVCVAIAFAVVGGAVVGLILRLPIWGDPADDNCFDDEVYWEVPEDEEGILPVLEYNNHMTHKHQDISESNFSVEQS", "output": "Functions as an ammonia transporter. May play a role in the elimination of ammonia in the gill (By similarity)."}]}
+{"id": "function_test_2694", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MATHDSKQLEILQYIYDTVENRGFPPTVREICAAVGLSSTSTVHGHLTRLERKGYLIKDATKPRALEITHAGLDALGIKPKDIPVIGVVTAGQPILAVQDVEDYFPLPPNLASDAGELFMLRVHGTSMINAGILNGDYVIVRKQTTAQNGEIVVAMTDDGEATVKRFFKEDLHYRLQPENDAMDPIILNHVQILGKVVGLYRTNID", "output": "Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair."}]}
+{"id": "function_test_2695", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MARILDNDVMGNEEFSDRTLRPQYLREYIGQDKVKEQFAIFIEAAKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPAVEKAGDLVAILNELEPGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTRAGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPRIANRLLKRVRDYAQIIGDGIITAQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGGPVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQKAYRHLGYPYQNT", "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA."}]}
+{"id": "function_test_2696", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSKRDFYEILGVSKTADNKEIKRAYRKLAMKYHPDRNSEDPDAEEKFKEASMAYEVLSSEEKRSAYDRMGHAAFENGMGGGGFGGGGGGNFQDIFGDIFGNFGDIFGQSRGGGGGRSRRGSDLRYVIELTLEEAVRGCKKEISFTAPAPCDTCDGKGAKNASDIVTCQTCHGQGQVRMQQGFFAVQQACPHCGGTGKQIKNPCSDCHGNGVKDKSRTLEVSIPAGVDDGDRVRLAGEGEAGGAGVQNGDLYVEVRVKQHNVFTRQGADLYMDVPVSITDAALGKEVEIPTLDGKVKIKVAEGTQSGKLLRVRGRGVTPVRTTMKGDLICRVVIETPVNLTREQKDLLRQFQDTLDGDSKHQQSPHKKSFFKKIGDLFD", "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins."}]}
+{"id": "function_test_2697", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDNRRSLAQPSFSNKVIDTNELKNLIVWAFRNYGIARAANMADKLKDLGFHYATQAGISLSLEDLRIPPSKQSLLLGTIEDIKATENKYRRGEITAVERFQKVIDTWNNASESLKQEVIKYFKETDPLNAVSMMAFSGARGNISQVRQLVGMRGLMADPQGQIIDLPISSNFREGLTVTDYFISSYGARKGLVDTALRTADSGYLTRRLVDVSQDVIIREVDCKTNKGIILEDLVDTQKILINLEQALSGRVLAENVFHPETNCLIAHTNQDVSPKLAKEITKAGIKKVLVRSPVTCNSRSSVCQYCYGWNLAHGRLVDLGEAVGIIAAQSIGEPGTQLTMRTFHTGGVFTGELAEQIYAPIDGQLIDLDIESYTDVRTRHGEQALITKKPTQVTIRSKKNQKSIINLSKGTTLLICDGELVSKDQVIAESPRRNRLMTERAQKHVVSDLSGKICFSNLTVEETDNNQYTTRITKTGGLIWVLSGEVYSISDSANVIVHKEDKTKAGTILAQTELINHYAGEVRIHQNTNSSITNIQVITESIVIPGCYIYTDVIHKKESYILETEKKQKFLFKAIPNQKIQDGYTVAELISDTYKTTSGGIIKYLDLNVSKKKTGLDKDAYEILSPGYILWISEETHEINKDSSLILVHNGDVIESGTELVKNIFSKSSGIAEIIEKDGIVREIIIKPGSIYKLSEVYSNNDKSRGFLRPGERLHNNISTDKLVYWEYIENEQMPYILIRPVIVYSIPETKSSLIENLVSQKPSQTKLKLVKRTPFRDGERVKSIEGVHLVTTNLVAEIEHRDDNLISSIEFSAKESGNNYFDLRLSTFETLSIKSIDVNKSEKQQSQTRIIVKNGEYIKPFTVVASTEIIAMSEGTVEEIYSEKNTSRRILIATSSDKKTFNIGKSTVKVSVGDWIRCGDFITENMTSLDSGQIIEISSRSVTLRIARPYLVSNGAILHVDNNALIRRGETLAILVFDRAKTGDIIQGLPRIEEILEARKKTDVLLNPHDILDASFDLYIECGLALYEAARLSFQEIQLLLVKEVQLVYQSQGVNISDKHVEVIVRQMTSKVKIENGEETGYLPGELVELQKIEQTNKAITLRNKINASYRPVLLGITQASLNTESFISAASFQETTKVLTEAAISGKLDWLRGLKENVIIGRLIPAGTGFNMYDNCNGSSLEKKNLTANTNDESTISSVRDDLDDIILDDRTARNYFSNKSVE", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_2698", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNHIRNFSIIAHIDHGKSTLADRLIQRCGGLQEREMEAQVLDSMDIEKERGITIKAQTASLKYKAQNGQIYNLNLIDTPGHVDFSYEVSRSLSACEGALLVVDASQGVEAQTVANCYTALDLGVEVVPVLNKMDLPNADPDNAKIEIEDVIGIDATDAIACSAKTGMGIDEILEAVVARMPPPRGNPAGALRAMIVDSWFDTYVGVVMLVRVVDGRLAKGERIKMMATGTTYNADSLGVFTPANEPRESLEAGEVGYIIAGIRELQAAKVGDTITLIKAGTGGAAFTATEPLPGFKEIQPQVFAGLYPTEASEYESLRDSLEKLKLNDSSLRYQPEVSQALGFGFRCGFLGLLHMEIVQERLEREFDQDLITTAPSVEYQVVQADGTVKMVENPSKMPDQGRLDEVREPIVTVHLYMPQDYVGAVMTLANQKRGVQMNMAYHGRQVMLTYEMPLAEIVMDFFDKLKSVSRGYASMDYEFKEYRAADVVKVDILLNGDKVDALSIIVHRSQSQYRGRAVVSKMREIISRQMYDVAIQAAIGSNVIARETIKAMRKNVIAKCYGGDISRKHKLLDKQKEGKKRMKQIGSVSVPQEAFLAILQVDA", "output": "Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner."}]}
+{"id": "function_test_2699", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSKEVVNTKAEASRVNALAAVRNYKVCPRLEYKTISGVQGPLVIIEDVKFPKYSEIVTIHLSDNTTRQGQILEVCGKKAVIQVFEGTSGIDNKNSYVEVSGDILKMPMSDEMLGRVFNGSGKPIDKGPNILADDYLDINGNPINPQCRVYPKEMIQTGISTIDVMNSIVRGQKIPLFSAAGLPHNEIGAQICRQASLVQGKDVLDHSDDNFAVVFGAMGVNMETARYFRQDFEENGKMERVCLFLNLANDPTIERILTPRIALTTAEYLAFEKEMHVFVILTDMSSYADALREVSSAREEVPGRRGYPGYMYSDLSTIYERAGRVEGRNGSITQFPILTMPNDDITHPIPDLTGYITEGQIFVDRNLYNRQIYPPINVLPSLSRLMKSGIGHNMTRIDHPYVSDQLYSNYAIAQDVKAMKAVIGEEALSNDDILYLEFLDKFEKRFITQNTYECRDIYQSLDIAWELLRIFPEDMLKKIKTDILSKYYPRHHAN", "output": "Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells."}]}
+{"id": "function_test_2700", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVLRGRAVLLAVLLAAGSLGRWAQKPRGAPSAISAIQPKANFDAQQFAGTWLLAAVGSACHFLQEQGHRAEATALHVAPQGAAMAVSTFRKLDGICWQVSQRYGATGVPGRFLLPARGPRGAVHVVAAETDYHSFAVLYLERARQLSVKLYVRSLPVSDSVLGAFEQRVAQANLTQDQVLFFPTYGFCEAADQFHILDEVRR", "output": "C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol (By similarity)."}]}
+{"id": "function_test_2701", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQMNIGRCGPVCFSCSAPPSKSYTHRALIIAALADGQSEIIGQLDADDTRMTARALMQLGVRLDWSRENIRVQGTGGHLKAPVEEINIQDSGTSMRLLTGVSLLADGPVVLTGSGRMQERPLGPLIDTLNNAGAKITCLKNPGCPPVRIDGTFPAGDMYVDGSISSQFISSLLIAAPYADNDVHIHLTGDPVSLPYIMMTIDSMRAFGAEVLVDGDDKEPVFTISSQRRYKPQTYGIEGDFSSSSYWFALAAICGGSATISGLNPQSAQGDRRLLEILVNMGCSITEKRESIILSRDPDVLLKGIKVDMADCPDIVQTVCMVAAVSSSPTRITGVHHLRMKESDRIAAIANGLTTLGGRVETEEDVIVIHPAPLHGGIIHPENDHRTAMSFAVLGCFIGDVTILDAECVTKSYPGFWEELRRIWQNAVLC", "output": "Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate."}]}
+{"id": "function_test_2702", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNKNKPFIVVIVGPTASGKTELSIELAKRINGEIISGDSMQVYKHMNIGTAKVTPEEMDGIPHHLIDILNPDDTFSAYEFKRLAEDLITDITNRGKVPIIAGGTGLYIQSLIYNYELEDETVTPAQLSIVKQKLSALEHLDNQQLHDYLAQFDAVSAENIHPNNRQRVLRAIEYYLKTKKLLSNRKKVQQFTENYDTLLLGIEMSRKTLYSRINKRVDIMLDHGLFREVQQLVEQGYESCQSMQAIGYKELIPVINGQMIYEDAVNDLKQHSRQYAKRQMTWFKNKMSVHWLDKENMSLQMMLDEITTQIK", "output": "Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)."}]}
+{"id": "function_test_2703", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQRKHKRILFVAVSFIALGCVSAFVLFELSKSISFFCTPTELVADPIKSSRYPIRVGGMIVKGSIVRHGDSVTFSITDLGTELEVTYRGVLPPMFGEDVGAIAKGRFVDGVFIAEELLAKHDEKYMPKKYSSSDAAVIGSS", "output": "Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH."}]}
+{"id": "function_test_2704", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MWIINWFYDVLSSLGLLNKHAKLLFLGLDNAGKTTLLHMLKNDRVAILQPTLHPTSEELSIGNVRFTTFDLGGHQQARRLWKDYFPEVNGVVFLVDAKDHERFPEAKAELDALLSMEELSKVPFVVLGNKIDHPDAVSEDELRHQLGMYQTTGKGKVPLEGIRPIEVFMCSVVMRQGYGDGIRWLSHFGN", "output": "Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SAR1 controls the coat assembly in a stepwise manner. Activated SAR1-GTP binds to membranes first and recruits the SEC23/24 complex. These SEC23/24-SAR1 prebudding intermediates are then collected by the SEC13/31 complex as subunits polymerize to form coated transport vesicles. Conversion to SAR1-GDP triggers coat release and recycles COPII subunits (By similarity)."}]}
+{"id": "function_test_2705", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQLQEIAQKLGCAYEGDPTLEIHSVASLAEARPGELSFLSEARYLPLLEQTQASAVIVEEGLALPCSIACLRGRDPRLLFAQAIELFYQPYRLPVGIHPTAVIDPSVELGEGVAIGPHAVVMEGVKIGDHTQIHPNVTIYPHVRIGSRCQLFANCVIHERTEIGDDCLIHSGAVIGDDGFGHIPLADGSWRRMLQAGRVVLEDNVEVGSNTTIDRAAVGETRIGRGTKIDNLVQIGHGVRTGSHCLIVAQVGIAGSTQLGHHVILAGQCGLAGHLHIGDGVRVAAQTGVTSDVPAGQTVAGYPHQPIAEWRKSMAVQRHLPELQRTLRKLEARVAKLEQNSTDRAPNAKMLEVGVDPETTCSS", "output": "Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell."}]}
+{"id": "function_test_2706", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKSSEIRQKFLQFFQSKGHSIVPSSSLVPGNDPTLLFTNSGMVQFKDVFTGKEKRPYTRATSSQRSVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDYFKQDAIRFAWELLTTVYKLPVEKLWVTVYQEDDEAYDIWAKEVGVPTERIIRIGDNKGARYASDNFWQMGDTGPCGPCTEIFYDHGPDIWGGPPGSPEEDGDRYIEIWNLVFMQFERDAAGNMTPLPKPCVDTGMGLERIAAVLQGVHSNYEIDLFQKLITAAARETGVQDLHDNSLKVIADHIRACSFLIVDGVIPSNEGRGYVLRRIVRRALRHGYKLGQTKPFFYRLVPDLVAQMGEAYPELANMAERVGQVLKQEEERFGETLEHGMKILDVALAQVPKGGLLDGNTLFTLYDTYGFPVDLTADICREREVEIDMAGFEAAMERQRDQARAAGKFKMAEGLNYEGAQTRFEGYEQLELSGAKVTALYVDGTQTDQVRAGQQAVVVLDATPFYAESGGQVGDTGLLVADGLRFAVADTLKVQAGVFGHHGLLEEGVLKVGDTLLARVDAVRRARTVRNHSATHLMHKALREVLGAHVQQRGSLVDPDKTRFDFAHDAPMTAEQIARVEAIVNAEVLANQAAQARVMAYDDAVKGGAMALFGEKYGDTVRVLDIGFSRELCGGTHVSRTGDIGLFKIVSEGGVAAGVRRVEAITGDNALVWVQEQNALLQRAAGVLRSPVAELPERIAQVQDQVKALEKDLEQARAKLAASAGNDLADKSAVEIKGVKVLAAVINDVDPKALRGMVDNLKDKLKPAIVLLAASADGKISLVGGVTADQTAKVKAGDLVGFVAAQVGGKGGGRPDMAMGGGTDVAALPAAIASVQDWVNERL", "output": "Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain."}]}
+{"id": "function_test_2707", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKALLDLFKQVSQDEQFDAIKIGLASPEKIRSWSYGEVRKPETINYRTFKPERDGLFCAKIFGPIKDYECLCGKYKRLKHRGVICEKCGVEVTVAKVRRERMGHIELASPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEAWCVIEPGMTPLKRGQIMSDDDFLAKTEEYGDDFRALMGAEAVRELLRTIDIDREVETLRGELKATSSEAKIKKISKRLKVLEGFQKSGIKPDWMVMEVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIILRNEKRMLQEAVDSLLDNGRRGKAMTGANKRQLKSLADMIKGKSGRFRQNLLGKRVDYSGRSVIVVGPQLKLHQCGLPKLMALELFKPFIFNRLEMMGLATTIKAAKKLVESQEPVVWDILEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQLEARTLMLASNNVLFPANGEPSIVPSQDIVLGLYYTTRERINGRGEGIFFADVAEVQRAYDNGEVELQTRITVRLKEHERDEQGEWQPVIRRHETTVGRALLSEILPRGLPFTVLNKALKKKEISRLINQSFRRCGLRDTVIFADKLMQSGFRLATRGGISIAMEDMLIPAAKEVILAEAGREVKEIDKQYSSGLVTSQERYNNVVDIWGKAGDKVGKAMMEQLATEPVVNRHGENVRQESFNSIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVTQDLVITEVDCGTSHGYSMKALVEGGEVIEPLRDRILGRVAAVDIVNPDTQETEITAGTLLDEDLVDLIDRVGVDEVKVRTPLTCETRHGLCAHCYGRDLGRGSHVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRSALASAVETKSNGTVGFASTMRYVTNAKGERVAISRSGELAIYDDNGRERERHKIPYGATVLVGDGDAVKAGTRLATWDPLTRPIVSEYGGAVRFENIEEGVTVAKQVDEVTGLSTLVVITPKTRGGKVVMRPQIKLVNDNGEDVRIAGTDHAVNISFPVGALITVRDGQQVAVGEVLARIPQESQKTRDITGGLPRVAELFEARSPKDAGMLAEVTGTVSFGKDTKGKQRLVITDLEGISHEFLIPKEKQVLVHDGQVVNKGEMIVDGPADPHDILRLQGIEKLATYIVDEVQDVYRLQGVKINDKHIEVIVRQMLRRVNITDPGDADFIPGEQVERSELLNENDRVIAEDKRPAQYDNVLLGITKASLSTDSFISAASFQETTRVLTEAAIMGKRDDLRGLKENVIVGRLIPAGTGLAYHLARKDKEALEAAEREAARQQANPFEEMPVAADIEVDVSLPFEGETPAE", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_2708", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSTTFKLDTSTSRANPTPAPMKRLTVPKIRARKKDGKTEEPLVMLTAYTARQAQLLDAHCDLLLVGDSLGQVIYGLPSTIPVTLRMMADHAAAVVRGSYHSVVVVDMPFGSYEQSPQQAFESASFLLKESGAAAVKLEGGEAMAETVAFLNQRGIPVMGHVGLTPQAVNVLGGYAARGRNDAEADKIVTDAKALDDAGAFAIVIEGVLEPIAVAATEAVRAPTIGIGASAQCDGQVLVTEDMLGMFERVPRFVKKYGDIAETIEATAKTYAEEVRARSFPGPEQLYQPK", "output": "Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate."}]}
+{"id": "function_test_2709", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLKLNLEGIYNFLDWRKHTQTYAPQIKSIHQKLHQDKQLKEKYLGWLELPLHFDFKEIEKMKQLKNFHPNLDVLVVIGIGGSYLGAKAGIEFLQTPFKKTKPEILFAGHQVSGNYLTNLLHFLKNKNWAINVISKSGTTLEPALAFRILKKEIEEKYGKQLAKNRIFVTTDSQKGVLLNLALKEGYQTFVIPDSVGGRFSVFTSVGILPFVFANLDVASMMKGALQSYHDTFQEDLLQNQAYKYALARYLFHTQQNKKMEILVSYEPNLLSFSEWWKQLFAESEGKEEKGLFVGATNNSTDLHSLGQFIQEGTKMLFETVLNVSSIKDDCVVPHILNELDNLNYVAGKTYSQINQKILQATRQAHIEGKVPNLEIVIPTLDAYHFGYLAYFFQKACAMSGLLLGINPFNQHGVEIYKQKMFALLKP", "output": "Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate."}]}
+{"id": "function_test_2710", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRVIITGGGTGGHVYPALAIARGLKEARPGVELLYIGTARGLEADVVPRAGLTLATITVQGLVRRQVWKNIPALVKTGRGLGEAWQQVRRFRPDVVVGTGGYVSGPVCLAAALQGVPVILHEQNAFPGVTNRLLAILARCVCLTFPEAASRFPRRAKLVTTGLPVRPEIIQADRDSCRQHFGLRPEQLFLVTVGGSQGARSINGAMLPILKELAGCQDVSLLQVTGRRDYEAYLQQVRTQGIDLAKYGNITIEPYVYNLEQALAAADLVIGRAGASFLAEVLARGLPSVLVPYPHAAANHQEYNARAVARQGAAVVVLDRELKGGRLYQVVFELLRSREKLKAMAAAAASLGRPGALEAIIQVILKTVESG", "output": "Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II)."}]}
+{"id": "function_test_2711", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MHSLSLISLALLSPLLVNAQLSGHVGPLTSSSSKASTKTCNVQDYGAKADKETDIGSAIEKAWDDCAEGGVVYIPSGDYAMFSRLKLSGGKASAIQLDGIIYRTGSDGGNLFMIEHSSDFEFFSSTSQGAIQGLGYEFHKDGSLNGPRLLRFYDVTDFSVHDVALVDSPAFHLSLDTCKNAEIYNMAIRGGDSGGLDGVDIWSENVWVHDVEVTNKDECVTVKSPAKNILVENIYCNWSGGCAMGSLGADTNISDVVYRNVYTWKSNQMYMIKSNGGSGSVSNLVLENFIGHGNAYSLDIDGEWSSMSTVSGDGVQLNNITVRNWKGTEEDGAARGPIKVVCAEKAPCTDITIDDFALWTESGDEQTYSCENGFGSGFCLQDGDGTSSYSTVITETAAPTGYEASSMSNDLSTAFGTDASIPIPTIPTSFFPGATPYSALAGAASGNAAKATSSATASRFRHRRGSH", "output": "Pectinolytic enzymes consist of four classes of enzymes: pectine lyase, polygalacturonase, pectin methylesterase and rhamnogalacturonase. Hydrolyzes alpha-D-galacturonopyranosyl-(1,2)-alpha-L-rhamnopyranosyl linkages in the backbone of the hairy regions of pectins (By similarity)."}]}
+{"id": "function_test_2712", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRVATQLRVGIVGGGWNGCHLALELKKQGHRVSLFEQKPDIFQGVSGNFGIRLHKGPHYPRSKATRDSCREALVKFCETYPELVVHHESAIYAHGEADALGNPSKVSDEAFRDVCYESPECTAVDPKANGFQGLISAYNLDEPSVAIGDRLRNTFKEKLGRAGIYVHLNATVDRIIHTEDTNRIQTGDGQYVFDVVINATGYTSLLPQNIADALPVDIGITYQTCIALVYEDQQPQEKPLSFIVMDGWFPCVMPAIDTNEPLQKKYILTHGSYTILGSFDRHEEGQELLDSLDEEAIAARIKPHCEREITRFWPGFLDRFQYRGWKGSVLAKLKTTSEFRSSLTFEKDGVIHIFPGKVSNVVTAAEEVVPLINDIARRRHGVVREWNGVRFTVSSAFHTHSKEIGDKPGLGEHHTSNLQTYVSLVTAN", "output": "Probable FAD-dependent monooxygenase; part of the gene cluster that mediates the biosynthesis of 5-hydroxy-2-hydroxymethyl-1,4-pyrone, also know as kojic acid, a by-product in the fermentation process of malting rice that acts as a chelation agent . Glucose might be converted to kojic acid by a combination of dehydrogenase and dehydratase reactions involving kojA and probably additional enzymes ."}]}
+{"id": "function_test_2713", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTASQTGPTTTAIAQRASELRQLLQQASYAYYVLDQPVMEDAVYDRLYRELQDLEQQHPSLITPDSPTQRVGEQPATGFESVQHRIPLYSLENAFDAEELRSWDQRWRKLAPDVPADAGYVCELKIDGAAIALSYENGLLVRGATRGDGTRGEEITANLRTIKSIPLRLQTDQPPEWLEVRGEAFLSLTRFKQLNTEREKHGEALFANPRNAAAGTLRQLDPRIVAERQLDFFAYSIQGPNDWANLDQAASLDCLQSLGFRVEPHRQTCPTLAEVEQYFSDWDARRRDLPYLTDGVVVKLQSRRLQDELGFTQKFPRWAIALKYPADEAPTQLQHVTVQVGRTGALTPVAEFSPVALAGTTVSRATLHNADRLRELDLHIGDTIVVRKAGEIIPEVVRVLTDLRPADAKPVVLPEKCPECGQPVQRPEEEAVTRCVNSTCPAIVRGALTHWASRDALDIEGLGEKLVDQLVSKGLVNAIADLYRLDAPLLASLERFGEKSAQNLVQAIAKSRQQPWSRVLYGLGIRHVGSVNAKNLAATFTSAEALAQATPDELAAVYGIGSEIADAVHQWFTVATNQNLIAALEQAGLQLHGEAASPRSQALAGQTFVLTGTLPTLSRNEAKALIEAAGGKVSGSVSKKTSYVVAGEEAGSKLEKAIALNIPQLNETQLLDLLAQAEG", "output": "DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA."}]}
+{"id": "function_test_2714", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNHSLKPWNTFGIDHNAQHIVCAEDEQQLLNAWQYATAEGQPVLILGEGSNVLFLEDYRGTVIINRIKGIEIHDEPDAWYLHVGAGENWHRLVKYTLQEGMPGLENLALIPGCVGSSPIQNIGAYGVELQRVCAYVDCVELATGKQVRLTAKECRFGYRDSIFKHEYQDRFAIVAVGLRLLKEWQPVLTYGDLTRLDPTTVTPQQVFNAVCHMRTTKLPDPKVNGNAGSFFKNPVVSAETAKALLAQFPTAPNYPQAGGSVKLAAGWLIDQCQLKGMQMGGAAVHRQQALVLINEDNAKSEDVVQLAHHVRQKVGEKFNVWLEPEVRFIGASGEVSAVETIS", "output": "Cell wall formation."}]}
+{"id": "function_test_2715", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPALEAAALDDIYWGCVQQTLEQGFNIARNAALLAEVPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQACLVGGVEHMGHVPMSHGVDFHPGLSRNVAKAAGMMGLTAEMLARMHGISREMQDAFAARSHARAWAATQSAAFKNEIIPTGGHDADGVLKQFNYDEVIRPETTVEALATLRPAFDPVNGTVTAGTSSALSDGAAAMLVMSESRAHELGLKPRARVRSMAVVGCDPSIMGYGPVPASKLALKKAGLSVSDIGVFEMNEAFAAQILPCIKDLGLIEQIDEKINLNGGAIALGHPLGCSGARISTTLLNLMEHKDVQFGLATMCIGLGQGIATVFERV", "output": "Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed."}]}
+{"id": "function_test_2716", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLAHSTAQDLILQQRSSDDHPQTNPRQTGCGAFIILSSVIAAISGLLVGYELGIISGALLQLQSLLELTCQQQEIVVSALLIGALVASLVGGCLIDLYGRRTTIIFTSILLVFANLLPVVVVSYGSLIAGRIFIGVSISLSAIATCVYIAELSPQDKRGMLVSLNELMIVAGILLAYICNYLFASVNNGWKYMFGLITPLAALQAVAMFFLPRSPRFLIMKGYDDAAGKVLQKLRATTDINEELTAIKSSIKAEYQYKFLDLFCSRDNMRARLLIGLTLSFFVQITGQPNILFYASTVLKSVGFQSTEAASLASTGIGVVKVVSTIPAIFLVDKIGSKTFLCIGSAVMAVSLVSVGLVSLQLDVNYNNICKVHTVQNHSLQDSFVYGPVALAKHNESLFEETGTWLESTKASYHSTSQNGTKLLHVSAPEDSSFGFTVKEPKVKSQSDEIPEYMKWLCLSSLLAFVAAFSIGLGPMAWLVQSEIFPAGIKGRAFAITSSMNWGMNLLISLTFLTLTEMIGLPWMLFGYALMSIASLVFVIMFVPNTKGRPLEEISKELANRSYMCNAVCHRRRSKKKLTPVALIQSPA", "output": "Insulin-regulated facilitative glucose transporter."}]}
+{"id": "function_test_2717", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLSINLNLIVAFLLALMGVLIYRSHLMSTLLCLEGMMLSLFILMTLLITHFHMFSMSMTPLILLVFSACEAAIGLALLVKISATHGSDHIQNLNLLQC", "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor."}]}
+{"id": "function_test_2718", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGVTKKPDLNDPVLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACNVGLAVLEPSMIGEPADPFATPLEILPEWYFFPVFQILRTVPNKLLGVLLMVSVPAGLLTVPFLENVNKFQNPFRRPVATTVFLIGTAVALWLGIGATLPIDKSLTLGLF", "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions."}]}
+{"id": "function_test_2719", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRLLKSHPLLKLVNSYLIDASQPSNISYLWNFGSLLACCLIIQIVTGVTLAMHYSPNVLEAFNSIEHIMRDVNNGWLVRYLHSNTASAFFFLVYLHIGRGMYYGSYRAPRTLVWAIGTVILILMMATAFLGYQHSPKWFDISNKGSISNKGNITNSLPPLLQRWGGRINKRLFNKNLVKRGYCTSSSLNSPEMSERLQTIINELGINPVYVYEDLNQPSSWKQILHDTRDLSGVYMIINKTTKDYYIGSASNNRFYTRFCNHVIHFTGSKIVKLAIKKYELKNFAFVILDLYPNVVTKENNKELLDLEDKYLKLLVPNYNILTEAGSSFGYKHTEIDRQKMKDLYSDARREKIGSLNRGKKFSPETIEKIREKALTRPPMSEETKIKCIANTRPVVLYNLNRTIYGKYSTILEAANAINCNEKTIRRALQTEKKLVKRQWIVEDFSDK", "output": "Mitochondrial DNA endonuclease involved in intron homing."}]}
+{"id": "function_test_2720", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAFRKSNVYLSLVNSYTIDSPQPSSINYWWKMGSLLGLCLVIQIVTGIFMAMHYSSNIELAFSSVEHIMRDVHSGYILRYLHANGASFFFMVMFMHMAKGLYYGSYRSPRVTLWNVGVIIFILTIATAFLGYCCVYGQMSHWGATVITNLFSAIPFVGNDIVSWLWGGFSVSNPTIQRFFALHYLVPFIIAAMVIMHLMALHIHGSSNPLGITGNLDRIPMHSYFIFKDLVTVFLFMLILALFVFYSPNTLGHPDNYIPGNPLVTPASIVPEWYLLPFYAILRSIPDKLLGVITMFAAILVLLVLPFTDRSVVRGNTFKVLSKFFFFIFVFNFVLLGQIGACHVEVPYVLMGQIATFIYFAYFLIIVPVISTIENVLFYIGRVNK", "output": "Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis."}]}
+{"id": "function_test_2721", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MELGTLLAQPGLWTRDTSWALLYFLCYILPQTAPQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPDYAAISRAILDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDAKPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRYSGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQLTVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGLRKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTDSNKDKSSNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFIYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKMWAFMSSRQQTALVRNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDNKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIYKSRKNNDIEQAFCFFYGLQCKQTHPTNSTSGTTLSTDLECGKLIREERGIRKQSSVHTV", "output": "Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus (By similarity)."}]}
+{"id": "function_test_2722", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEERLVSGYELTEDENEFSLRPRRLSEYIGQQKVKETISIFIEAAKKRNEALDHVLLFGPPGLGKTTLATIIANELGVDIKITSGPALERPGDLAAILTNLGEKDVLFIDEIHRLPRIVEEVLYSAMEDFALDIMLGKGPGARSLRLSLPKFTLIGATTRAGLLTSPLRDRFGMVHRLEFYSVEELMLIINRSAALLKTEITPEGSFEIAKRSRGTPRIANRLLKRVRDYAEVRSSGVINLENAKAALDLLEIDELGLDPTDRLILKTMIEKYQGGPVGIEAIAAAISEEVDTIEDVYEPFLLQIGFIKRTPRGRVVTKLAYDHLGIAYNKNAGELSLW", "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. RuvB forms 2 homohexamers on either side of HJ DNA bound by 1 or 2 RuvA tetramers; 4 subunits per hexamer contact DNA at a time. Coordinated motions by a converter formed by DNA-disengaged RuvB subunits stimulates ATP hydrolysis and nucleotide exchange. Immobilization of the converter enables RuvB to convert the ATP-contained energy into a lever motion, pulling 2 nucleotides of DNA out of the RuvA tetramer per ATP hydrolyzed, thus driving DNA branch migration. The RuvB motors rotate together with the DNA substrate, which together with the progressing nucleotide cycle form the mechanistic basis for DNA recombination by continuous HJ branch migration. Branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves cruciform DNA."}]}
+{"id": "function_test_2723", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MASRVESAAWRALQAHQQEIAPLQMRQLFAEDSARFERFSLRWQGMLCDYSKHRITARTMELLLDLARSAEIEAARNAMMQGQPINLTEKRAVLHTALRKPQSVPFAVDGQNVAADVAEVLAQMEGCCNRIISGEWVGYTGKAMTDIVNIGIGGSDLGPYMVTEALRPFAHGKLNVHFVSNVDGTHLSETLKKLNPETTLFIVASKTFTTQETLSNAMSARAWFLQCAVDAAHIAKHFVAVSTNRAKVVEFGIDEANMFRFWDWVGGRYSLWSSIGLSIAMYLGFEKFRQLLAGAYAMDEHFCSAPLESNMPVIMAMLGIWYSNFFGCTSHAVIPYDQYLHRFPAYLQQLDMESNGKRVTRDGTVVDYATGAVIWGEPGTNSQHAFFQLLHQGTQIIPADFILPLKTQNPIGAHHDMLASNCFAQTEALMKGKSEEEVERELVAAGADAATIAALLPHKVFPGNRPTTTLLLDELNPFTLGSLIALYEHKVFVQGIVWNINSFDQWGVELGKQLANVILPELQASSNAAAHDSSTNALINAYRAQRYC", "output": "Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate."}]}
+{"id": "function_test_2724", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNVYYEQDADLGRLQGKNIAVLGYGSQGHAHALNLKDSGMNVCVGLRPDSSSCAKAREAGLRVEPVADAVKWADIVMVLLPDQTQKAVYEAEIAPNMVAGNTLAFGHGFNIHYNQIVPPADVDVIMIAPKSPGHLVRRTYTEGNGVPCLIAVHQDATGEAKKTALAWAKGIGGTKAGVIETNFKDETETDLFGEQAVLCGGSAELIKAGFETLVEAGYPEELAYFECMHELKLIVDLYYEGGLSRMNYSVSDTAEYGGMTRGPRLITSAVKAEMKKVLEEVQDGRFAREFIDECNGGYKNLNRLREENSGHAIEKVGAKLRNMMSWLVRK", "output": "Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate."}]}
+{"id": "function_test_2725", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MMTTPTLAPLTTADLAPLVPELVLIGGAFALLMLDLFVSQRNKVWTHLFSVAVLAVVLVLLATGTGGQGDIFNGMFVRDTAADVMKTVIVLVSGLSLVYGWTYLRERNLYQGEIPVLVLFATAGMMLLASAGSLLMVYLGLELLALCSYALVASNRDNGLATEAAMKYFVLGSLASGLLLYGMSLVYGATGTLSLAGIHDAIEGSNERTLLLTGTIFMIAGVAFKLGAAPFHMWLPDVYQGAPAPIALFISSAPKLAAFGMAYRLLEVGMGPLSPQWHLLIGGLSAVSLVVGNLMAIAQSNLKRMLAYSTVSHIGFLLMGVAGGGEEGYAAAMFYAVSYTIMSTASFGAIIALSRNGFEAENIDDFKGLNARNPWMAGLVLCIMASLAGIPPFLGFWTKLAVLGAAVKGDMLWLALVGVICAVIGAYYYLRVIKVMYFDEPVGEPLPANNDRVLGTVLGVNALALLALGLAWSPIMVWCQRAFAGLA", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_2726", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPAMDVLLANPRGFCAGVDRAIEIVKRAIETLGAPIYVRHEVVHNRFVVDDLKQRGAIFVEELDEVPDDATVIFSAHGVSQAVRQEAERRGLRVFDATCPLVTKVHFEVARHCRAGRDVVLIGHAGHPEVEGTMGQWSRERGAGTIYLVEDIEQVATLDVRQPDNLAYTTQTTLSVDDTMGIIEALRARYPAMQGPRHDDICYATQNRQDAVRDLARQCDLVLVVGSPNSSNSNRLSELARRDGVESYLIDNASEIDPAWIVGKQHIGLTAGASAPQVLVDGVLARLRELGAAGVSELEGEPESMVFALPKELRLRLVS", "output": "Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis."}]}
+{"id": "function_test_2727", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MISNLFTKIFGSRNDRTIKNLRKTVALINALETQLEALSDDDLKAKTAEFRERYDNGQSLDDLLPEAFAVVREASKRVNGMRHFDVQLLGGMVLHQGRIAEMRTGEGKTLTATLPAYLNGLTGKGVHVITVNDYLAKRDAETNRPLFEFLGLTVGCNVPGMMPQQKKQAYVADITYGTNNEFGFDYLRDNMAFSIDERVQRPLFYAVVDEVDSILIDEARTPLIISGPAEDSSELYTEINTMVPLLELQEKEDEEGIEGDGDFTIDEKSKQVHLTERGQIKVEELLTERGLIAEGDSLYSAASITLLSHVYAALRAHKLYQKDVDYVVKENEVIIIDEHTGRSMEGRRWSEGLHQAVEAKEGVNIQNENQTLASITFQNYFRLYETLAGMTGTADTEAFEFQSIYGLDTVVMPTNKPMVRDDRADLVYLTQEEKYEAILVDIKDCQERGQPVLVGTISIESSEYLSQFLRKEKIKHNVLNAKFHAQEADIVSDAGLPGTVTIATNMAGRGTDIVLGGNWHSEVEKLENPTDEQIAEIKAAWKIRHDAVIDAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMDDALMRIFAGERMTNMMRKLGMQRGEAIEHPWVNRAIENAQRKVEARNFDVRKQLLEYDDVANDQRRVVYSQRNELLEEGDISETITVIRGDVLSNIIDQYIAPQSLAEMWDVPGLEERLKQDFLIELPITQWLADDNKLYEEKLRERIEESVGQAYKQKEEMVGDSVLRQFEKAIMLQSLDQHWKDHLAAMDHLRQGIHLRGYAQKNPKQEYKRESFELFAEMLENLKIDVVSILSKVQVRAEEDVEKVEEQHRKSENAPREYQHEEVEHVGGEAPQSATVMARSEPKVGRNDPCPCGSGQKFKQCCGKLK", "output": "Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane."}]}
+{"id": "function_test_2728", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQVTETQKEGLKRAYTITVTAAELDAKVQEKLVEAQPDIEMKGFRKGKVPLAMLKKQFGPRLLGDAMQDAIDGAMRDHLETSGDRPAMQPEVRMVDGETWKEGTDVVVEMKYEALPEIPEIETSKVSLERLVVKADEAAIEEALKNLAESAQNFEDRRKGSKAKDGDQVVIDFKGSVDGELFEGGSAEDYPLVLGSGSFIPGFEEQLVGTKVDDEVTVKVSFPAEYGAKHLAGKEAEFACTVKAVKAPKAAELDDELAKKYGAEDLAALKSQISERLEAEYKGASRAVLKRALLDQLDQMVSFELPSKLVEAEAHQIAHQLWHEEHPEEHGHNHGNIEPTDEHKALAERRVRLGLLLAEIGRKAEVTVTDAEMTQAVLAQARQYPGQERAYFEFVQKNPQIQQQLRAPIFEDKVVDLILEGATVTEKEVGKDDLQKAIEALDEM", "output": "Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase."}]}
+{"id": "function_test_2729", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAKAKFERNKPHVNIGTIGHVDHGKTTLTAAITKYFGEFRAYDQIDGAPEERARGITISTAHVEYESDTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVNAADGPMPQTREHILLGRQVGIPYMVVYMNKVDQVDDPELIELVEMEIRELLSSYDYPGDDIPIIKGSALAAMNGTDKEIGEDSIRALIAAVDEYIPTPARAVDQPFLMPVEDVFSISGRGTVATGRIERGVVKVGEELEIVGIRPSKKTVCTGVEMFRKLLDQGEAGDNVGLLLRGVDRDGIERGQVLCKPGSVKPHTKFEAEAYILTKEEGGRHTPFFANYRPQFYFRTTDVTGTVQLPEGTEMVMPGDNLKFNVELIAPIAMEEKLRFAIREGGRTVGAGVVSKIIA", "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."}]}
+{"id": "function_test_2730", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDHIRNFSIIAHIDHGKSTLADRIIQLCGGLSDREMESQVLDSMDLERERGITIKAQTAALTYRARDGKVYNLNLIDTPGHVDFSYEVSRSLSACEGALLVVDASQGVEAQTVANCYTAIELGVEVVPVLNKIDLPAANPENAIAEIEDVIGIDAMDAVRCSAKTGLGVEDVLESLIAKVPPPKGDPDAPLQALIIDSWFDNYVGVVMLVRIVNGTLRPKERIKLMATDAQYAVEHVGVFTPKSRNLESLSAGQVGFIISGIKELTAAKVGDTVTHATKPAPEPLPGFKEVKPQVFAGLYPVEANQYDALRESLEKLKLNDASLQYEPEVSQALGFGFRCGFLGLLHMEIVQERLEREFDMDLITTAPTVVYEVVQSDGTTIMVENPAKMPEPARIAEIREPIVTVNLYMPQDYVGSVITLCEQKRGTQINMQYHGRQVQLTYEIPMAEIVLDFFDRLKSVSRGYASMDYEFKEYRTSDVVKVDMLINGDKVDALSIIVHRSQSQYRGREVAAKMREIIPRQMYDVAIQAAIGAHIIARENIKALRKNVLAKCYGGDITRKKKLLEKQKEGKKRMKQVGSVEIPQEAFLAILRVEDK", "output": "Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner."}]}
+{"id": "function_test_2731", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIEFQNVHKTYRVAGKDITALHPTSFSIENGQVFGLIGHSGAGKSTLLRLINRLEQSSGGKIIVDGEEVTALDANGLRRFRQQVGMIFQHFNLLASKTVADNVALPLTLAGELSRAEIDQRVAELLARVGLSDHAKKYPAQLSGGQKQRVGIARALATKPKILLCDEATSALDPQTTASVLQLLAEINRELKLTIVLITHEMDVIRRVCDQVGVMDAGVIVEQGSVADVFLHPKHPTTKRFVQESEQIDESEQRDDFAHVPGRIVRLTFQGEATYAPLLGTVARETGVDYSILAGRIDRIKDIPYGQLTLAVTGGDMDAAFARFTAADVHMEVLR", "output": "Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system."}]}
+{"id": "function_test_2732", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAPSPSKRKERSEDKAKERGKEKAPGKEATDKDRGRDKAKKRRSASSGSSSSSRSRSSSSSSSSSGSSSGSSSGSSSSASSRSGSSSSSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKQPKRDEKERKRRSPSPRPTKVHIGRLTRNVTKDHILEIFSTYGKIKMIDMPVDRYHPHLSKGYAYVEFEAPEEAEKALKHMDGGQIDGQEITASAVLTPWPMRAMPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRRSPVRRRSRSPARRRHRSRSSSNSSR", "output": "Component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Putative component of the spliceosome which enhances the formation of the ATP-dependent A complex of the spliceosome. May participate in mRNA 3'-end cleavage. Also mediates increase of mRNA abundance and translational efficiency (By similarity)."}]}
+{"id": "function_test_2733", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPSLKTKGAAGKFASLLLVLALSACSRPAPPPETSGELRVGTRNSPATFYIGHDGETAGFEHDLILAFSRAQNWTLSWTEKSRPQALFDMLERREIHLAAAALPQAVVKDRHLISGPILFETPVHVVYRTADRAPRGVAGLAGKKLAFIIGSGHGPMLMRLKRKHPELSWAAVENVWPEELLAQLQAGKYDAVIINGMDFDAMRNFYPGLAVAFDLPYKQKIVWALSPGSSHAFRNALARFVERARSDGTIKRALERYFGHVKRLGSSDILGILQRRPQRLPDLREHFQEAQTLSGIDWRLLAAIGYQESQWNRLATSPTGVRGVMMLTGETADRMGVSDRLNARESILGGARYLALLKDALPARIAEPDRTWLALAAYNQGQGHLEDARRIAQARGGDPNSWADVKEALPYLSRGSYAKVMKYGYARGGEALRFAENIRNYYDILLRLEPEYDPLINLGRGEDGLPPPG", "output": "Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella."}]}
+{"id": "function_test_2734", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRVAPSGGPPHHHAMIRATPPKRRLKAGTINVAPSFMRERDLMECGVWPVAGCDEVGRGPLAGPVVAAAVVLDPNHIPKGIDDSKRLTAARREELFEEIVATASFAVACAPIERIDRDNILRASLWALARAVHALPDTPKHVFVDGRDRIDIACACEPVIGGDGLVLSIAAASIVAKVTRDRLMCKLARDCPGYGFETHKGYAVPGHLEALGRLGPSSHHRSFFAPVVAARERHRALLAGASASISETSATVAVEAVI", "output": "Endonuclease that specifically degrades the RNA of RNA-DNA hybrids."}]}
+{"id": "function_test_2735", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSYIGLQQDSGEYKIQKIHAREILDSRGNPTVEVDVFTPKGFGRAGVPSGASTGTNEALELRDADPNRYGGKGVLTAVKNVNTIIQKELLGLDVRNQREIDELMIELDETDNKSNLGANAILGVSMAVARAAADSLNVPLYRYLGGSNAFTLPVPTMNVLNGGKHAGNDLAIQEFMIQPKGAETFYEALQIGAEIYHVLGKILEKKYGRSSTNVGYEGGYAPKMSESTEALDALAQAIEEAGYTDTEVTIGLDAAASEFYEDEAYAIDGKKLSAPELMDYYVELVNSYPILSIEDPFYEEAFEDFEALTNELWDTIIVGDDLFVTNIERLSKGVDMGAANALLLKVNQIGTISEAFDAANMASRNGYTVIVSHRSAETEDTTIADISVAIGAEMIKTGAPARGERTAKYNQLLRIEEDLGEVAHYVQL", "output": "Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis."}]}
+{"id": "function_test_2736", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDKFQIQGNGPLKGEIRVSGAKNAALPILCAGLLTADTVTIDNVPNLQDTRTMLKLLRQMGMHAEMTGSTATLKGTDINSPEAPYELVKTMRASILVLGPLVARFGEARVSLPGGCGIGARPVDQHIKGLQAMGAEISIEHGFIHARASRLKGARVVTDMITVTGTENLLMAATLADGETVLENAAREPEVTDLANLLVKMGAKIDGIGTDRLIVQGVDKLHGATHSVVADRIEAGTFLCAAAASLGDLVLRDIPPLILDAVLIKLREAGANIETGDDWIRLSMSQRAQAVSFRTSEYPAFPTDMQAQFMALNAVAEGTARITETIFENRFMHVQELNRLGANITAEGNTAVVTGVPRLSGASVMATDLRASASLVIAGLVADGDTVIDRIYHLDRGYDRMEDKLSAVGAKIRRIA", "output": "Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine."}]}
+{"id": "function_test_2737", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKYRIKALLLASSLIITTITSVQAKEELLDRVAAIVNTGVVLESEVNDLLVNIKQQAKKNNQSLPSDKALRIQVMDKLINDSLLSQMGQRMGIQISDAQLDQTLNNMAREDKLTLAQFRQQVIDEGTSYEKYRENVRIELVSGEVSRNSVRRRIFVSPQEVDNLLKVMKEQSSNNVEYHLGHILIEFPADASQEDLAAAKTRATKVVELLNDGSDFAKIAITSSGDANALKGGDLGWKNINEMPTLFSELINDKPKDTIVGPIRTGLGYSIVKVLDIRGRKVVEVEEVKASHILIKPSIILSDEKAKSLLQGFLNQIDAGEATFEELAKEHSEGPTSVRGGDLGWADPKNYDPAFTEALATMKKGGYHKPFRSSFGWHIIKLEDRRMVDATSQLNENRAYQILFNRKYGMESTRWLKETRDEAYIEIFEQDNK", "output": "Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation."}]}
+{"id": "function_test_2738", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSAHLILIDALNLIRRVYAVQERPFIQIKQDHDDELSASTLKQVLFNTQNTCVNALIKIIDQHQPTHALTVFDSQEPCWRYQLFEGYKKGRKKMPDHLANKLIDIQDAFMEQGVDSLTSDEDEADDLIATLAVKMALHGQKVTIISTDKGFLPLLSPNIHIYDYFNRRYLDEEHVQSKFSVKTSQLIDFWTLTGDNTNKIEGVSGIGQVTAAKLLNQYGSLKAILEATDLKDSLAEKLTQSLEQMDLARKLLTLKQDIPLGFNLKDIRLTTSSSAHEINANINLTTDDKS", "output": "Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment."}]}
+{"id": "function_test_2739", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLNKREYYTKEDLLASSRGELFGKNGPTLPAPNMLMMDRVIKMTKNGGNYNKGFIEAELDIQSDMWFFNCHFIKDPVMPGCLGLDAMWQLVGFYLGWLGGEGKGRALGVKEVKFTGQILPTSKKVTYFIHFRRIINRKLIMGMADGEVSCDGKIIYTATDLKVGLFKNSTVF", "output": "Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length."}]}
+{"id": "function_test_2740", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MELNAYIGRAGTGKSKAIIEEIKEKMKQDPLGDPIVLIAPTQNTFQLEQAFVNDKTLNGSLRTEVLHFERLSYRVFQEVGGLMEQQLSKAGTEMMIYDIIQQHQSELRLYQSQVKYYGFSEKLYEQIQDFKKYAVSPQQLETYIAENNLQTRTKHKLQDIALVYKHLEDRINGEYVSTEDSLQRFIEMMDQSEWLKRAEIYIDGFHNFSTLEYQIIQSLVKYAKKVTIVLTTDGDRDLFSLFRKPSESLTHIEEIANNLNIQLHSRQFLDVQRFIHNDLKHLEQNFNALQFEPIPTEGNVEILEASGMREEINEVARRILRENREQGRRFQDIAILYRDESYAYLMESILPQYDIPYNIDVKSSMTHHPIMEMIRSLIEVIQTGWQFDPLMRLFKTNILTKKFKDSQYLIDILENFVLERGIYGKRWIDDKYFDIEQFRKMGLKRQPLTDEERETFERVIQLKNDVMKKVMLFEEKINNASTAIAFATAFYEAMEAFDLPSQLMTDRDTLDVNGEHKKAEEIDQIWNGLIQILDDLVTVFDDQSMSKTRFLELFDIGLEQLEFIMIPQTLDQVSIGTMDLAKVDNKQHVYLVGANDGVLPQTVTASSLITDEEKKYFQEQSSIELSPTADILQMDEAFVCYIAMTRSRAHVTFSYALMGASGDVKEPSPFLHQIQQLYTNLEVQNIHHQHQAEPLRLMEHPHQTKIALFESLKAWLDDELVAETWLDTYQVMRNDTRLNDGLTYLLSALTYDNQTVQLNPSLSKALYGSTINASVSRFEGYQACPFKHFASHGLRLNERTKYKLENFDLGDIFHRVLKFISEKVNGDFKNLNPKQIHKLTTEALSEILPEVQFNLLNSTAYYRYLSQRIGAIVETTLTALKYQGSHTKFTPQRFEASFRRKPKDQSELLATPLQTKQGIPINIRGQIDRIDTYQQGDESFVNIIDYKSSKYSGTLDLTKVYYGLQMQMMTYMDIVLQNKSRLGLTDMTKPGGLLYFHVHEPRIKLAWNQLSEDKRDTEFINSFKLSGLLNSATSVLDAFDTRLEPSYNSDIVPLGLKKDGGIKSNSKVADEQTIYKLIKHNKQNFIETASNIMDGHTEVAPMKYNQTLPCDFCNYKSVCHVDGMIDSKRYRTVDESINPLEAIQDVDLESEGE", "output": "The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddB nuclease domain is not required for chi fragment generation; this subunit has 5' -> 3' nuclease activity."}]}
+{"id": "function_test_2741", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTHSEYRDEYCGAVTESLIEQTISVVGWVHRRRDHGGVIFLDMRDRAGILQVVVDPDTPEAFATADAVRPEYVLKITGRVRRRYEGTENANMTSGHIELLAKEIEVLAKSETPPFPLNDEKSTVSEDLRLKYRYLDMRRPQMQDRMVFRAKATSAIRRYLDDHGFLDVETPILTRATPEGARDYLVPSRTRPGNFFALPQSPQLFKQLLMVAGFDRYYQIAKCFRDEDLRADRQPEFTQVDIETSFLNEEEIMNINEGLIKHVFKTMMDVEFEKFPRMTYAEAMRDYASDKPDLRIPLKLIDVADLMKDVDFKVFAGPANDPKGRVAALRIPGGASLSRKQIDAYTKFVGIYGARGLAYIKVNDASNINNGVDKESGLQSPIIKNMTDDVLVSLIERTGAESNDIIFFGADKASVVNDAIGALRQKIGLDLEMTTCEWAPLWVTDFPMFEETEDGRWTSMHHPFTKPKGSVEELKTNPESALSIAYDMVLNGTEVGGGSLRINTLEMQTAVFEALGIDDQEAEDKFGFLLDALKFGAPPHGGLAFGLDRLIMLMVGASSIRDVIAFPKTKTAECPLTQAPAEVNTKQLRELGIRVREKVQADTSKPAE", "output": "Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn)."}]}
+{"id": "function_test_2742", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSWSILELIRNNPEVLKENLKRRFIDTSTVDKAVELDKKWRQTLQEVERLRHEHNLISSQIPKAPKEQKSELINKAKELLKTLEDKEKELQKIEEERENLLLSLPNLVHDSVPIGPDESYSVPIRFWGKFKVYKDDVNEFLKQTNGHKVDYEVINWKPVGHADMLENVLRLGDTKKAGEVAASRFYYLFNDIVWLDLALLLYAIDTITSRGYTLVLPPYMLRGEVIKSVIDLDTFKDAIYKIEGEDLYLIATAEHSIAALYYKEEIPKEELPLKLVGVSPAFRKEAGAANKDLKGIFRVHQFHKVEQFIFSSPEDSWKYHEEMIENAEEIFRGLGLPYRVINIASGDLGAPAAKKYDLEVWMPAQAKFREMVSCSNCLDWQAYRMRIRYVEKNNKKGYLHTLNSTAIASTRAITAILENFQKEDGVVEVPKVLRKYLETFSGAPKEYIYPKKKPNTTS", "output": "Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)."}]}
+{"id": "function_test_2743", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MASASIPTDPDVSTICEDFMNLLPDEPSDDFALEVTDWANDEAIGSTPGEDSTTSRTVYVERTADTAYNPRYSKRRHGRRESYHHNRPKTLVVVLPDSNHHGGRDVETGYARIERGHRRSSRSYNTQSSRKHRDRSLSNRRRRPTTPPAMTTGERNDQTHDESYRLRFSKRDARRERIRKEYDIPVDRITGRAIEVVSTAGASVTIDSVRHLDETIEKLVVRYATIQEGDSWASGGCFPGIKQNTSWPELMLYGHELYRTFESYKMDSRIARALRERVIRGESLIEALESADELLTWIKMLAAKNLPIYTNNPIVATSKSLLENLKLKLGPFVRCLLLNRDNDLGSRTLPELLRQQRFSDITCITTYMFVMIARIANIVVRGSKFVEYDDISCNVQVLQEYTPGSCLAGVLEALITHQRECGRVECTLSTWAGHLSDARPYGKYFKCSTFNC", "output": "Multifunctional regulator of the expression of viral genes that mediates nuclear export of viral intronless mRNAs. This immediate early (EI) protein promotes the nuclear export of viral intronless mRNAs by interacting with mRNAs and host NXF1/TAP (By similarity)."}]}
+{"id": "function_test_2744", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MHGESPIKRRESRKIWVGSVPVGGDAPIAVQSMTNSDTNDVAATVAQINRLEAAGVDIVRVSVPDMDAAEAFGRIKQQVKVPLVADIHFDYKIALRVAELGVDCLRINPGNIGREDRVRAVVDAARDRGIPIRIGVNAGSLEKDLQKKYGEPTPAALVESALRHVEHLERLNFKDFKVSVKASDVFMAVEAYRLLAKEIIQPLHLGITEAGGLRSGTVKSAVGLGMLLAEGIGDTIRISLAADPVEEVKVGYDILKSLHLRSRGINFIACPSCSRQNFDVVKTMNELEGRLEDLLVPLDVAVIGCVVNGPGEAKEAHIGLTGGTPNLIYIDGKPAQKLTNDNLVDELEKLIRQKAAEKVEADAALIARG", "output": "Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate."}]}
+{"id": "function_test_2745", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTAAETRILELRAELDQHNYRYHVLDEPSIPDAEYDRLFRELKALEAEHPELVTSDSPTQRVGSAALSAFTQVRHEIPMLSLGNAFEEVDMREFDRRVNEGLDLPAGDLFGGGAAVEYSCEPKLDGLAVSLLYQDGVLVRGATRGDGTTGEDISVNVRTVRNIPLKLQGSGWPATLEVRGEVFMSKAGFERLNAAQLEAGGKTFANPRNAAAGSLRQLDSKITASRPLEFCCYGLGQVSADIADTHIGNLERLKQWGMPISRELRLAKGIDECLDYYREIGERRNALPYEIDGVVFKVNSIASQRELGFRAREPRWAIAHKFPAMEELTELLDVEFQVGRTGAVTPVARLQPVKVAGVTVSNATLHNMDEVARLGLMIGDTVIIRRAGDVIPQVVQVVTERRPENARPVQIPESCPVCGSHVERTQLVKRSKGRETVSEGAVYRCVGRLACGAQLKQAIIHFVSRRAMDIEGLGDKTIEQLVDENLIASPADLYRLKYEQIIDLEGFAEVSSNKLLKAIEDSKRPALARFIYALGIPDVGEETAKVLARSLGSLERVQQALPQVLTYLPDVGLEVAHEIHSFFEDSHNQEVIGSLLAADQCGLVLQDQGELGAEFAASTTLGGMLDKLNIPSVGPGAAQKLADKFGSLQGVIEADWLDMRQALPEKQAKAVREFFDNPANAQLAQAIEQQLQAFGMHWQSEKKVVAGLPLAGQTWVLTGSLELMSRDVAKDKLESLGAKVAGSVSAKTHCVVAGPGAGSKLAKANELGLKVLDEEAFVAFLTEHGVPT", "output": "DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA."}]}
+{"id": "function_test_2746", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAYVALCKALYDYVAQAEDELNLTEDDHLYILESDDPEWWKAKLRRLDEHGTPIQDDSDDSTVGLVPANYVEEAEPIRLSRALYDYEAQTEEELSMAEDELLRVYESDGVWLLVKKQGNDPLSGGEGRLGYVPANYVDEAEAVDTGAAPAVEDEYTAADEDDEDDDDTDVTGSGAPIPQIHLPQTAQLGKGDNIKMWPVSALDSKKKKKKGTLGIGNASLFFASESDKTPVKKISILHIASHSLEKGKTLHLQLSPEAGLSESTLDFHAGSKDAANDIIRKIEVSKANALTAAAAPVPVPVPAPAPPAAAAAAASAAVPLPPPPPPAPPVASAAALPPPTRTTSATLPPPVRKNVSFQSQPAAEPEEAVEHGVAMYDFEAQGDDELTVTENEHLIILEKENDDWWKVRNDAGQEGVVPASYVEATDASAAAGASSGATAAAALAAQQEEEERLRREEEEAATVAEAERQREAVDRQREARERGEREEKERARREALKAQPVPAPPKLTQRPSTTDVSRAAKNVAIPQGRSAPERPKDGGSRSKPSPTNTRMWTDRTGAFKVEAEFLGFNQGKIRLHKMNGVVIEVAIEKMSNGDIAFLEDITGKKLNPTDEEIAASAARRRERERERQSSRPQSSAVAGMPREDRERERERRKEKEREQRRRESARSGPKRNVDWFEFFLAAGVDVDDCTRYASSFERDKIDETVLADLDPSTLRSIGLREGDIIRVTKFIDKKYRRDKSHSSLSSSRASGRANANTAADLERQIKADEELARKLQEQESSARRGDSVSPAPPQLFSGPDGTLKNNTRRGRPTPKSTSSSNVDAASLAAASESLARTATPPARTATASPAVAPKRTGSSLANGFDDDAWTPRPPSTKPTTPARPTVASPAPSTPAAPAAPPAPTPPPAAVAVASSAPPADPNSALFEKLAAMKAPSASVSPRPGVSPSPGSSFLGQSQMYNPNAPRGPFAPVPANQGLLQPLVPTQGTGQFVPTKTGMMGMQMTGMQPQLTGWGMQGMQGMQPQMTGFNNSMGSMSVMGGMGMQPQATGFGNGNGYGMNGSSPFTGGQISTQQTGLVGMGMQPQATGFNNFGQNAQQMMTQQTGFGMGSQQQGQQLQAEQDEKEKFKASNIFQQMKTGAFAKDPNAAPQSSEKYDALRPQPTGFQPGGVMPQFTGMGFGQSAQQQQQQQQQQYPYNNAYGGGFGGGF", "output": "Component of the PAN1 actin cytoskeleton-regulatory complex required for the internalization of endosomes during actin-coupled endocytosis. The complex links the site of endocytosis to the cell membrane-associated actin cytoskeleton. Mediates uptake of external molecules and vacuolar degradation of plasma membrane proteins. Plays a role in the proper organization of the cell membrane-associated actin cytoskeleton and promotes its destabilization (By similarity)."}]}
+{"id": "function_test_2747", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTNIQTQLDNLRKTLRQYEYEYHVLDNPSVPDSEYDRLFHQLKALELEHPEFLTSDSPTQRVGAKPLSGFSQIRHEIPMLSLDNAFSDAEFNAFVKRIEDRLILLPKPLTFCCEPKLDGLAVSILYVNGELTQAATRGDGTTGEDITANIRTIRNVPLQLLTDNPPARLEVRGEVFMPHAGFERLNKYALEHNEKTFANPRNAAAGSLRQLDPNITSKRPLVLNAYGIGIAEGIDLPTTHYDRLQWLKSIGIPVNPEIRLCNGADEVLGFYRDIQNKRSSLGYDIDGTVLKINDIALQNELGFISKAPRWAIAYKFPAQEELTLLNDVEFQVGRTGAITPVAKLEPVFVAGVTVSNATLHNGDEIERLNIAIGDTVVIRRAGDVIPQIIGVLHERRPDNAKPIIFPTNCPVCDSQIIRIEGEAVARCTGGLFCAAQRKEALKHFVSRKAMDIDGVGGKLIEQLVDRELIHTPADLFKLDLTTLTRLERMGAKSAENALNSLENAKSTTLDRFIFALGIREVGEATALNLANHFKTLDALKDANLEELQQVPDVGEVVANRIFIFWREAHNVAVVEDLIAQGVHWETVEVKEASENLFKDKTVVLTGTLTQMGRNEAKALLQQLGAKVSGSVSSKTDFVIAGDGAGSKLAKAQELNITVLTEEEFLAQITR", "output": "DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA."}]}
+{"id": "function_test_2748", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSIVTVQLGQCGNQIGFEVFDALLSDSHSSQGLCCKRENEAYQASCKERFFSEEENGVPIARAVLVDMEPKVINQTLSKAAQSGRWKYGQHACFCQKQGSGNNWAYGYSVHGPRHEESIMDLIRKEVEKCDSFSGFFIIMSMAGGTGSGIGAFVTQNLQDQYSNSLKMNQIIWPYGTGEVIVQNYNSILTLSHLYRSSDALLVHENDAVHKICAKLMNIKQISFSDINQVLAHQLGSVFQPTYSAESSFHYRRNPLGDLMEHLVPHPEFKMLSIRNVPHMSENSLAYSTFTWAGLLKHLRQMLISNAKMEEGIDWHARPPLSGLPSLGKMSLNKDLHFNTSIANLVILRGKDVQSADVEGFKDPALYTSWLEPVNAFNVWKTQRAFSKYEKSAVLVSNSQFLVKPLDMIVRKAWNMFASKAYIHQYTKFGIEEEDFLDSFTSLEQVVASYCNL", "output": "Acts as a positive regulator of hedgehog signaling and regulates ciliary function."}]}
+{"id": "function_test_2749", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MINLGDKQSTIVVAMSGGVDSSAVAAMLHEQGHNVIGITLQLYDHGMAVGKKNACCAGQDIYDAKMVANKLGIPHYVLDYESKFKESVIDNFVDSYLQGETPLPCVQCNKSVKFRDLIKTARELGAAQLATGHYVRKVNGDNGAELHTGLDPAKDQSYFLFTTTKEQLEYLSFPLGGLTKDETRRLASKFGLEVADKPDSQDICFVPDGNYKSVINKIRPGASESGKIIHVNGFELGEHSGIINYTIGQRRGLGIAYNEPLYVVKIDPKDNIVYVGPESALHVQEFIIKNINWLADEIKDNEKLEVEVKIRSTRPPRLAEISKLDDDKMKVKFLSEEKAVAPGQACVIYAGERVLGGGWITRDIR", "output": "Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34."}]}
+{"id": "function_test_2750", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTPGIRPLVAGNWKMNGKGESLTELRAIAAGLSSDLGRKLDAVICVPATLLSRAAETLEGETVGLGGQDAHFKTSGAHTGDISPEMLKEAGATHVILGHSERRTDHHESNKLICAKTEAAWAAGLVAIVCVGETASERKAERALDVIGDQLSGSLPDGVTAENTIIAYEPVWAIGTGLTPTVQDVRAAHAFMREQLIERFGAKGAHLRLLYGGSVKPSNAAELLGVADVDGALVGGASLKAADFLAICETYRNL", "output": "Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)."}]}
+{"id": "function_test_2751", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSNNTDLSPVHVIGGGLAGSEAAWQIAQAGVPVVLHEMRPVRGTDAHKTEQLAELVCSNSFRSDDAETNAVGVLHAEMRLAGSLIMACADAHQVPAGGALAVDREGFSQAVTARLEAHPLITIEREEITGLPPTEWGTTIIATGPLTAPSLAEAIAAETDADALAFFDAIAPIIHFDSINMDVCWFQSRYDKVGPGGTGKDYINCPMDKEQYEAFVAALIEGDKTDFKEWEGTPYFDGCLPIEVMAERGPETLRHGPMKPMGLTNAHNPTVKPYAVVQLRQDNALGTLYNMVGFQTKLKYGSQTGIFKMIPGLENAEFARLGGLHRNTYLNSPVLLDNVLRLKSRQTLRFAGQVTGCEGYVESSAIGLLAGRFTAAEKLSQAAVPPPPTTAFGALLGHITGGHIVTNDEPGKRSFQPMNVNFGLFPPVDVPKPEGKRLRGKEKTIAKKRALSARALADCRNWLSLY", "output": "Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs."}]}
+{"id": "function_test_2752", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MVTGMIIKKIKELTKEEEEKIINRNKANFEEILPTVMEILKDVKEKGDEALKYYTKKFDGVEIEDFKVTDEEIEEAYNSVDYKVVEAIERAKENIYFFHKKQMEQIKDLNVENNGIILGQVVRAIEKVGCYVPGGRAFYPSTVLMTTIPAKVAGCEEIYITSPPTKDGKGNPATLIAGDIVGVSAIYKVGGVQAIGALAYGTETIPKVDIIVGPGNIYVTTAKKMVYGEVAIDFLAGPSEVLIIADETANAEFVALDFIAQAEHDPNASCVITTTSEKKAEEIKNKIFEEIEKAERKEIILKALENSAILIGDLEECIEFSNKYAPEHLEILTKNPEEVLNKIKHAGSVFLGEYSPVPVGDYASGTNHVLPTSQFARMSSGLNVETFLKKITYQKLDKESLKNIADIVITLAEAEGLFGHAEAVRRRLK", "output": "Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine."}]}
+{"id": "function_test_2753", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAKETRFYPYTSNGGATLGVSGPDFAILAGDTRSTAGYNINTRYEPKVFTIQDARDRSIVISVIGFAADGRALKERLDAIVAMYKYQHGKNIGLRACAQRVSTMLYEKRFFPYQLQTMVAGIDADGQGAIYYYDPAGCIEKRSHCAAGEASSLMLPFLDSQAPRLQPLSLQTAQQLVRDAYTGATERHIEVGDHLQMLVVTREGVSEQLVDLKKD", "output": "Proteasome subunit beta type-6; part of the inp gene cluster that mediates the biosynthesis of fellutamide B, a mycotoxin that acts as a proteasome inhibitor . In the first step of fellutabmide B biosynthesis inpC activates 3-hydroxydodecanoic acid to generate 3-hydroxydodecanoyl-AMP that is then loaded onto the T0 domain of inpB . The 3-hydroxydodecanoyl-S-phosphopantetheinyl-T0 is sequentially extended with L-Asn and L-Gln by the two CAT modules of inpB . The linear lipodipeptide from inpB is then transferred onto inpA for the addition of the third amino acid, L-Leu . Reductive releasing of the lipotripeptide by the TE domain of inpA produces (2S)-fellutamide B . InpF might be involved in the release and transfer of the lipodipeptide from inpB to inpA . The inp cluster-encoded proteasome subunit inpE confers resistance to internally produced fellutamides . The MFS efflux transporter inpD may contribute to fellutamide resistance as well ."}]}
+{"id": "function_test_2754", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSKIVKVLGREIIDSRGNPTVEAEVHLESGFVGMAAAPSGASTGSREALELRDGDKARFLGKGVLKAVAAVNGPIAEALVGKDAKNQAEIDQIMIDLDGTDNKANFGANAILAVSLANAKAAAAAKSMPLYAHIAELNGTPGVFSMPLPMMNIINGGEHADNNVDIQEFMIQPVGAKTLKEGLRIGAEVFHNLAKVLKSKGYSTAVGDEGGFAPNLKSNAEALEVIAEAVAAAGYELGKDVTLAMDCAASEFFDKEAGIYNMKGEGKTFTSEEFNHYLAELANQFPIVSIEDGLDESDWTGFKHQTELLGDKLQLVGDDLFVTNTKILAEGIEKGVANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSDRVAKYNQLIRIEEALGEKAPFNGLKEVKGQ", "output": "Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis."}]}
+{"id": "function_test_2755", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTVKTPVYLDYAATTPVDKRVAEKMIPYLTETFGNPASNSHAFGWTAEEAVEKARADIAALINADPKEIVFTSGATESDNLAIKGAANFYKTKGKHLITVKTEHKAVLDTMRELERQGFEVTYLGVQENGLIDLEELKAAIRDDTILISIMWVNNEIGVVQNIPAIGEICRERKIAFHVDAAQACGKVPVDVEAAKIDLLSMSAHKVYGPKGIGALYVRRKPRVRLEAQMHGGGHERGFRSGTLPTHQIVGMGEAFRIAKEELAQDTAHYLKLRDIFLKGIEGIEEVYINGDLEHRAPNNLNVSFNFVEGESLIMAVKELAVSSGSACTSASLEPSYVLRALGRNDELAHSSLRITFGRMTTEEEVQFAAELIKSKIGKLRELSPLWEMFKDGIDLNSIEWAAH", "output": "Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins."}]}
+{"id": "function_test_2756", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKHKSEFLNFIQERGYLCQCTNIEGLDQLLLQNNYVVAYIGFDCTASSLHVGSLIQIMMLRHLQKFGYKPIVLLGGSTTKIGDPSGKDKARSVLPIEDINQNISGIKKALKKMVYFNDGKAGAIIVNNADWLDSIKYIDFLRDIGAHFSVNRMLSFDSAKTRLDREQNLSFLEFNYMLLQAYDFAELNKKYGCRLQIGGSDQWGNIVNGIELGKKLNLPELFGLTTPLLLSAQGKKMGKTESGTVWLDGDMLKPYDYWQYFRNIDDQDIGRFLRFFTDLPIDEIKKLESLKNQEINEAKKALATEVTKICHGDKEAELAQSSAVSVFENGDSSLLPDYTITKKQVANGISLIDLLHDIGLEPSKGAAKRLIQGNGCKVNDYTINDINYIINSKSFKDQSFIKLSAGKKRHIKVMVS", "output": "Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr)."}]}
+{"id": "function_test_2757", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNKAKLIDHTLLKTDSTKEQIDTIINEAKAYQFKSVCVNPTHVQYASEQLKGTDVLVCTVIGFPLGATTTAVKSYETKDAINNGAQEIDMVINIGALKDGRFDKVQNDIEAVVQAANGKTVKVIIETVLLTEKEKIKACQLSEAAGAHFVKTSTGFAGGGATVEDVKLMKDTVGDRLEVKASGGVRNLEDFNNMIEAGATRIGASAGVQIIQGLESNTDY", "output": "Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate."}]}
+{"id": "function_test_2758", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNASHQDTGFFTEALSERDPELFGAITSELGRQRDEIELIASENIVSAAVMQAQGSVMTNKYAEGYPGRRYYGGCQYVDIAENLAIERAKQLFGCGFANVQPNSGSQANQGVFQALIKPGDTILGMSLDAGGHLTHGAAPNQSGKWFNAVQYGVRQQDNLLDYDQVEALAKEHRPKLIIAGGSAIPRQIDFARMREIADMVGAYLHVDMAHFAGLVAAGEHPSPFPHAHVATTTTHKTLRGPRGGMILTNDEDIAKKVNSAIFPGIQGGPLMHVIAAKAVAFGEALRPEFKTYIQQVIANAQALSDQLIKGGLDTVTHGTDTHVVLVDLRPKGVKGNATEKALGRAHITCNKNGVPFDPEKPTVTSGIRLGSPAGTTRGFAETEFRQIADWIIEVVDGLAANGEDANEAVEDKVKAQVAALCAKFPIYPNL", "output": "Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism."}]}
+{"id": "function_test_2759", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPGTLIIITAPSGAGKTTLVSGLLERDPQVNLSVSYTTREPRPGERDGREYHFVDVATFRALRDRGEFLEWAEVHGNYYATSKVWLKQQIATGRDILLEIDWQGAQQVRKSFPDAVGVFILPPSLEELEARLRGRGTDSDDVIMRRLLGARGEMRHVGEFDYVILNNDLQCALDDLVAVVRASRLRYANQHERHLQYFDFLEQD", "output": "Essential for recycling GMP and indirectly, cGMP."}]}
+{"id": "function_test_2760", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAIERTLSIIKPDAVAKNVIGKIYQRFEDAGLKIIASKMVHLSEREAGQFYAVHKERPFFKDLVSFMISGPVMIQVLEGESAIATNRDLMGATDPKKADAGTIRADFAESIDANAVHGSDAPETAAVEIAFFFPGMNVYTR", "output": "Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate."}]}
+{"id": "function_test_2761", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYNANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDQTEHPGPLPETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDIVTIDYRVRGFTRDVNGMKHFIDHEINSIQNFMSEDMKSLYDMVDVNVYQENIFHTKMLLKEFDLKHYMFHTKPEDLTETERQQITAALWKEMREIYYGRNISAV", "output": "Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine."}]}
+{"id": "function_test_2762", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MMNPLIIKLGGVLLDSEEALERLFTALVNYRESHQRPLVIVHGGGCVVDELMKGLNLPVKKKDGLRVTPADQIGIITGALAGTANKTLLAWAKKHHIASVGLFLGDGDSVNVTQLDEALGHVGLAQPGSPKLINMLLENGFLPVVSSIGVTDDGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTASKAEQLIDQGIITDGMIVKVNAALDAARALGRPVDIASWRHAEQLPALFNGTPIGTRILA", "output": "Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate."}]}
+{"id": "function_test_2763", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTAAENVCYTLINVPMDSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDFLVDEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKACHANPSERARFIRCIYNLLQSSSPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEIRRSLGEIPIVESEIKKEAGELKPEEEITVGPVQKLVTEMGTYATQSALSSSRPTKKEEDRPPLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSLPKKPITDDDVDRISLCLKVLSECSPLMNDIFNKECRQSLSHMLSAKLEEEKLSQKKESEKRNVTVQPDDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLASKLNKVTQLTGFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPHDFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPATCTDAEFRQMWAEFEWENKVTVNTNMIDLNDYLRHILKSTNMKCLTPEKALSGYCGFMAANLYARSIFGEDALANVSIEKPIHQGPDAAVTGHIRIRAKSQGMALSLGDKINLSQKKTSI", "output": "The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Plays a functional role in facilitating the transport of kappa-type opioid receptor mRNAs into axons and enhances translation of these proteins. Required for limiting lipid storage in lipid droplets. Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association of adipocyte surface triglyceride lipase (PNPLA2) with the lipid droplet to mediate lipolysis. Involved in the Golgi disassembly and reassembly processes during cell cycle. Involved in autophagy by playing a role in early endosome function. Plays a role in organellar compartmentalization of secretory compartments including endoplasmic reticulum (ER)-Golgi intermediate compartment (ERGIC), Golgi, trans-Golgi network (TGN) and recycling endosomes, and in biosynthetic transport of CAV1. Promotes degradation of Nef cellular targets CD4 and MHC class I antigens by facilitating their trafficking to degradative compartments (By similarity)."}]}
+{"id": "function_test_2764", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAAEPNKTEIQTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWNWFQLRCMQVGGNANATAFFRQHGCTANDANTKYNSRAAQMYREKIRQLGSAALARHGTDLWIDNMSSAVPNHSPEKKDSDFFTEHTQPPAWDAPPLSLQGPSSQPRLQRAVAWHSRSMAPTQTCLAPHPKPHWNWKSSIIGKKKPAAAKKGLGAKKGLGAQKVSSQSFSEIERQAQVAEKLREQQAADAKKQAEESMVASMRLAYQELQIDRKKEEKKLQNLEGKKREQAERLGMGLVSRSSVSHSVLSEMQVIEQETPVSAKSSRSQLDLFDDVGTFASGPPKYKDNPFSLGESFGSRWDTDAAWGMDRVEEKEPEVTISSIRPISERATNRREVENRSSGLESSEARQKFAGAKAISSDMFFGREVDAEYEARSRLQQLSGSSAISSSDLFGDMDGAHGAGSVSLGNVLPTADIAQFKQGVKSVAGKMAVLANGVMNSLQDRYGSY", "output": "GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes (By similarity)."}]}
+{"id": "function_test_2765", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTAPNVNTLWAETLVGELVAGGVDAVCLSPGSRSTPLTVAFAEHPDIEVFSHLDERSAAFFALGRARRTGEPTPLVCTSGTAAANYHPAVIEANQSGVPLLLLTADRPPELIDSGANQTVDQEKLYGDAVRWYRDMPEPEAEPRKVRMLRTTAARALAESTGSDPGPVHLNCRFRKPLEPTPMPEDDPAGVPADWAGGDNGAKIGRDGPFVTTSEGVETPDEQTVRRVQDALEAAERGLIVAGPADQGLSADSLERLAAATGFPVLADPLSDLRFGPHVDRLDVPVCGGYDGYLGSDSVDQWDDPDVVVRFGASPTSKPLRHYLRDADCQQFLVDPAGGWSEAEFTATNLLVANPDATADALAGETLGGVAASWREQFIRAEQTHWDAVTETASETYWEGGVLSDVTALAPDPATLFISNSMPIRDMDRFGGPRDADLTVLGNRGASGIDGITSTALGAGSATSDPLVLVTGDLAYYHDMNGLLALGRCAVDATVVLLNNDGGGIFHMLPIEDHPTFEDQFRTPHGLDFEPTEALYSLQFERVADRRQFRERFAESVQTDGTQVIEVRFDAGDSHAVRDQLTEQVAETLAGD", "output": "Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC)."}]}
+{"id": "function_test_2766", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSTSFENKATNRGVITFTISQDKIKPALDKAFNKIKKDLNAPGFRKGHMPRPVFNQKFGEEVLYEDALNIVLPEAYEAAVTELGLDVVAQPKIDVVSMEKGKEWTLSAEVVTKPEVKLGDYKNLVVEVDASKEVSDEDVDAKIERERQNLAELIIKDGEAAQGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEDQLVGAKAGDEVEVNVTFPESYQAEDLAGKAAKFMTTIHEVKTKEVPELDDELAKDIDEDVDTLEDLKVKYRKELEAAQETAYDDAVEGAAIELAVANAEIVDLPEEMIHEEVNRSVNEFMGNMQRQGISPEMYFQLTGTTQEDLHNQYSAEADKRVKTNLVIEAIAKAEGFEATDSEIEQEINDLATEYNMPADQVRSLLSADMLKHDIAMKKAVEVITSTASVK", "output": "Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase."}]}
+{"id": "function_test_2767", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPVRFRGLSEYKRNFRWKTPELCSPSQEQKSPWAGLRSDQLGITREPNFISKRRVPYHNPQISKSFEWTGDCDSDDPVETEALKTAESLAEHSNDVNQENTETPEGPRLPPKVRSHSSDSGVETALALAGNSMKKTPPVAPPNQKEAFVSPKKEAEKVNNGLHRVLQRKGGMNTPHLSTFPRNSEYQSQFVWKSPHEKSPILAAEEALYNTKREELIQKPAEDASKQEKSEQKHPKRKNKQHISQKPLSLHTHRGKMNTEYRSKFLSPAQYFYKDGAWSRIRSKVPNQASQNPLNSMWYMEVRELRARAKAYRQRIEGTHFSRYHLNQLLSDNNSLWDVSSNSSSEEGISNDIRALDLAGVSEKETAPRPKMLQQPGSREQSHQDDTEKKGLSDAPTVPVKRRLVWGEQEGTAEKDSQQLREEEEKENEQAAVVTQNLEKNNEGINEDNRIEGENTCLPNSPAAVSESSSVSSEPGGRLPTPKLRALGRAQRTHHDLTTPAVGGAVLVSPPKFKSSTSQQRMRSLGTDPSSVGQGAREASQRRSFRPGAKLKAVSLLTSPPAGLGTVDPLPLRQDQWHPNGVSGETVAINSAYQERSSTPPVLKSTKNRPMPCWSPSPRIQGTLKDPEFQHNGNVGNPKMGSFQLPLQERNYNNEDDRLSQISARSAASSSLASQILERAQKRKEDFWGKT", "output": "Microtubule-binding protein that negatively regulates centriole duplication. Binds to and stabilizes microtubules."}]}
+{"id": "function_test_2768", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAKNTVSARFRKVDVDEYDENKFVDEEEAGEGQQGPDEGEVDSAIRGGNMMGALQAVLKNPPINTKNQSAKDQAEHLVLKVLISFKANEIEKAVQSLDKNSMDLLMKYIYKGFESPSDNSSAVLLQWHEKALAVAGVGSIVRVLTARKTV", "output": "Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (By similarity). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (By similarity). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (By similarity)."}]}
+{"id": "function_test_2769", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTRAKRKKEHIDHALSTGQKRQTGLDDITFVHVSLPETELSQVDTSTKIGELFLSSPIFINAMTGGGGKATFEINRALARAAAQTGIPVAVGSQMSALKDPDERPSYEIVRKENMKGLVFANLGSEATVEQAKRAVDMIEADMLQIHLNVIQEIVMPEGDRNFTGRLRRIEDICRSVSVPVAVKEVGFGMSRDTAARLFNVGVQAIDVGGFGGTNFSKIENLRRDKAVEFFDQWGISTAASLAEVSSISGDRPIIASGGIQDALDLAKSIALGASAAGMAGYFLKVLTASGEEALAAEIESLIEDFKRIMTVLGCRTIEQLKKAPLVIKGDTYHWLKARGVDPFVYSMR", "output": "Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)."}]}
+{"id": "function_test_2770", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRMPAGFLINAMKKQNLVILGSTGSIGKSTLSVIEHNPEKYHAFALVGGRNVDLMVEQCVKFQPEFAALDDENAAKQLAEKLKSAGKKTKVLAGQKAICELAAHPEADQVMAAIVGAAGLLPTLSAVQASKTVLLANKETLVTCGQIFIDEVKRTKARLLPVDSEHNAIFQSLPPEAQQQIGFCPLKELGINKIVLTGSGGPFRYTDLTEFDNITPEQAVAHPNWSMGKKISVDSATMMNKGLEYIEARWLFNAGAEEMEVIIHPQSIIHSMVRYIDGSVIAQMGNPDMRTPIAETMAYPGRIVSGVTPLDFYQLSGLTFLEPDYERYPCLKLAIEAFAAGQYATTAMNAANEIAVEAFLNRMIKFTDIARVNAKVVELIQPQQINCIDDVLAVDKQSRLVAKEVIVSLKA", "output": "Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)."}]}
+{"id": "function_test_2771", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKQLYWYTCGEGDCDLVLLHGWGLNSGVWHCIIDRLAPHFRLHLVDLPGYGRSQDYGAMSLADMAERVAQQAPKQALWLGWSMGGLVASQIALSQPECVRGLITVSSSPCFTARDEWPGIKPEVLAGFQHQLSDDFHRTVERFLALQTLGTESSRQDARLLKSVVLQHQMPDVEVLTGGLEILRTADLRTALSGFTLPFMRVYGHLDSLVPRKVASLLDSAWPQTQSVVMQGAAHAPFISHPNDFAKLILNFAEENKK", "output": "The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters."}]}
+{"id": "function_test_2772", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MATQTVENGSRSRPKPTTVGNLLKPLNSEYGKVAPGWGTTPLMGVAMALFAIFLSIILEIYNSSVLLDEISMN", "output": "One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly. PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation."}]}
+{"id": "function_test_2773", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MMLESLARVFKVQLPAYLKRLPIPDSIAGFIRLTVLEWLRLLPFLGVLALLGYLAIRPFLPKKKQQKDSLINLKIQKENPKVVNEINIEDLHLAKAAYCRCWRSKTFPVCDGSHNKHNELTGDNVGPLILKKKEV", "output": "Regulator of autophagy that contributes to antagonize becn1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of bcl2 with becn1 and is required for bcl2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy (By similarity)."}]}
+{"id": "function_test_2774", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLKNQSNSVHVDGSHNNSSNYNDEVSSIAKSIRNADESVNFITFNQDASCIALGLKNGYKIFNCKPNFGKCYQFKKNESIGKIEMLYCTSLIAIVGLGEEVGSSPRKLKIINTRRQSTICELIFPSTILQVKLSKSRMIILLEEQIYIYDVTTMKLLHTIETSPNGNGLCTLSADNCDGKNNSYLAYPSPPKTITHDSLLVNGINTNGGMNSIQNNIQSVSNSPNRIGDVIIFNTTTLQPLSVIEAHKSALAAITLSTDGTLLATASDKGTIVRVFSVATGLKLYQFRRGTYPTKIFTLSFSFDNKYVLATSSSGTVHIFRLGEEESLENKHKRKRNSKKLKLNPEYETITEENENEIQKDDAEDDDIIQDDGDDSDADDDDDESLEVIPSKHRKLSQDSNNSFTSFNSAFSNDDNKDNKSEPLIDQTRLSVARLIRRSSQTLGRKAAQKMGDFLPTRFSSILEPTRNFASLKINSVSKDIKSIAIINNEVQEDLVPQAYLNAKENNPSPPKDISVNTAKDLLPLNLLHINVVTSEGYFYTYGLDPDRGGDCILLHQYFLLD", "output": "The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation-induced autophagy. Involved in correct ATG9 trafficking to the pre-autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity)."}]}
+{"id": "function_test_2775", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTLRDVEKLRLWRLKIFRNQQPILRAKPPHASRKTQYLFQKIDNVKSQFGTDGKGDLLWQRDGMNPYHDLYDPGDLKTHRLSVTKLLTKSWCELRFAYDLYSRLPLFREAHLAAGERTHQKLENSEHTPVIRPQDIPQFSETVEIVEDDLHVLAASWAETITRLIHLFSSGDAREILCHGYLNKETNQLYDPMETEVWDPSQHILISGIIDHLTLTSKNGNLPLNNHHRSIDDSIAKLKNTRNEFAKNGLTIQISDVKTRTRKFIPPQESVQNATKLQLMYYRHFLLSLGTDSDNTYEMLLYNARIRGVDVDQPLNPANCLLIMIQMDGFVGDFVKLQNGDGFQFPKFDNAPISHSFTLADAKHHQFLQNINSHELAGQLLNGTFAKPITLRYFAMRLAQMYSMLTPLISEKLKVEYYHNNECFQEVEFVNDKKSLGESCRSASSFWFGKRAIEPVEATTFNYNQYCKHCDYRDHCAWIKDSLAKSTKLGDELTQIARRIHNI", "output": "Single strand DNA specific 5' exonuclease involved in mitochondrial DNA replication and recombination. Releases dinucleotides as main products of catalysis. Has the capacity to slide across 5'double-stranded DNA or 5'RNA sequences and resumes cutting two nucleotides downstream of the double-stranded-to-single-stranded junction or RNA-to-DNA junction, respectively (By similarity)."}]}
+{"id": "function_test_2776", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEENLERTESLAREADDCHPIFRIAPSTVEFNKLRKRLLRHIRQAFDDFSMLSSGKKWLVALSGGKDSYGLLALLLDLKWRGLLPVEILACNLDQGQPGFPKHILPDFLNSYQIPHRIEYQDTYSIVTDKLVHTQTYCSLCSRLRRGNLYRIAREEGCSALVLGHHRDDVLETFFMNLFHGGRLAAMPGKLINDEGDLFVLRPLVYAAEEDMEKFSQAMQFPIIPCNLCGSQDGLQRNAMKEMLKDIERKMPGRKDTMIRALTNVRPSHLLDKKFFDFKNLF", "output": "Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system."}]}
+{"id": "function_test_2777", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSKEHTLSQNISRVNFKELQQIIKMGLVQGNLIPAFAGAWLAVVMTNHSFLSSIPQILLMLLGSTLIMGGACALNNYYDQDIDRIMPSKQNRPTVNNRITDQNLLLLSFGMMLVGEICLFLLNIPSGVLGLMGIVGYVSYYSIWSKRHTTWNTVIGSFPGAVPPLIGWVAIEGQISLTAIALFLVVFCWQPIHFYALAIKRKDEYALANIPMLPSVKGFKRTRVSMFIWLIILLPVPLLLINLGVVFVVLATLLNLGWIALGLTTFKKNSDQTKWATQMFIYSLNYLVIFFVLAVIVSLLTLI", "output": "Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group."}]}
+{"id": "function_test_2778", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSKSIEKMISHLKNQGFVFQGSEIYGGLANSWDYGPLGCEVKNKLKKVWWDFFVKKNPLNVGLDSSIILNSKVWKASGHIDGFNDPLIDCKNCKSRWRADKLIEEFDSSINTGIMTSAQLEDYINQNNILCKKCQKKDFTQIRQFALMFKTNQGVLEDDSSIVYLRPETAQGIFINFKNVQRSMRKKLPFGIGQIGKSFRNEITPGNFIFRTREFEQMELEFFFDPSDQKDWFKYWLDQIELFLTKKICLDKSNYKIRENLKDELSHYALKTSDIEFNFPFGWGELWGISHRSDFDLKVHQNLSKEDLTVLKEENNQKVLANVIEPSVGVERLMLAIFWQAYTEEQLEENNSRTVLKLPYNLAPYQVAITPLSKQLNQNAHQLFLELLKDFDAVYDETGNIGKRYRRQDAIGTPFVITYDFQTLEDQKVTIRYRDTMKQERILISQLKDFLNSQFN", "output": "Catalyzes the attachment of glycine to tRNA(Gly)."}]}
+{"id": "function_test_2779", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTTALEEQNTQQASVAGRVVRVIGPVVDVEFPRGELPALYNALTVEVTLEAVAKTITLEVAQHLGDNLVRAVSMAPTDGLVRGAVVTDSGKPISVPVGDVVKGHVFNALGDCLDEPGLGRDGEQWGIHRDPPPFDQLEGKTEILETGIKVIDLLTPYVKGGKIGLFGGAGVGKTVLIQEMITRIAREFSGTSVFAGVGERTREGTDLFLEMEEMGVLQDTALVFGQMDEPPGVRMRVALSGLTMAEYFRDVQHQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGVLQERITSIKGKSITSLQAVYVPADDYTDPAPATTFAHLDATTELDRAIASKGIYPAVNPLTSTSRILEPGIVGERHYAVAQRVINILQKNKELQDIIAILGMDELSEEDKITVQRARRLERFLGQNFFVAEKFTGIPGSYVPLAHTIDAFERICNGDFDHYPEQAFNGLGGLDDVEAAYKKMTEK", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits."}]}
+{"id": "function_test_2780", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFDFMTLEKVWEKGPLVHNITNIVVANDSANGLLAIGASPIMGSAKEEMDELAKMADVLVINIGTLDGELVTAMKIAGRAANVAGTPVVLDPVGVGATSYRRKVVQELLAEIQFTAIRGNAGELAAIAGEAWEAKGVDAGVGSADVLSIAEKVANEWSTVVIISGEVDVISDGTRFAKVANGSALLPRITGSGCLLSAVCGSFMAVQDDAFRASVEACASYAVASEYAEIELERKLPGSFRPQFLDALASWSVEKTRAKAKIQESGEHK", "output": "Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)."}]}
+{"id": "function_test_2781", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKVALVYNDKVETLAVVKALEKLLNARKIEIDPENPDVVITIGGDGTLISGFHKYQNLVDKIRFIGVHTGHLGFYTDWRNFEINKMVDNLTKKQPSSASYPLLELIITTGAGEKKKLLALNEATIKRVSKTLKADVYIRDQFFESFKGDGLCVSTPTGSTAYSKSLGGAVIHPRLKALQMTEIASINNRVFRTLSSPIVIAPDEWITIKPETGSDDHYVVTFDGYEFNHKHIKKIEYRISQHVIRFDKYQHTHFWNRVEDAFIGQPKDKQ", "output": "Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP."}]}
+{"id": "function_test_2782", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGAEVFHSLKKVLGEKGLASGVGDEGGFAPNLGSNIRRAGYTAVISHRVAKYNQLLR", "output": "Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)."}]}
+{"id": "function_test_2783", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNANTDILSLRVHAALDALRRGLPVIVADDADRENEADLILAADTLTVPEMARMIRDGSGIVCLCLTPERAERLQLPPMAAENGSRYGTAFTVAIEAAQGVTTGVSAADRTTTIRAAIHPDAKPGDLVRPGHVYPIVARAGGVRERRGHTEASVELARLAGFSPAGVLCELMNPDGTMMRGQQVQDYAERHDLPQLSVAELAEWLQREPA", "output": "Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate."}]}
+{"id": "function_test_2784", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAKVYNFSAGPAVLPHQVLAEAQSELLDWHGSGMSVMEMSHRGKEFMEIIHDAEQDLRQLMGIPAGYKVLFLQGGASLQFAMAPLNLLGDKDSIDIVNTGHWSKLAIKEAKRYAKVNVVASSEDRNFCYVPEEAAWQRDPNAAYLHYTSNETIGGLQFPYIPAEQHGVPLVCDMSSDFLSREVDVSRFGMIYAGAQKNIGPSGLTVLLIREDLLGKARADIPTMLNYQVHADADSMYNTPGTYPIYIAGLVFKWLKEQGGVKGIATRNEEKAGLLYHVIDSSGGFYSTHIEQPFRSKMNVVFKLRDEALDEIFLLEARKNGLAQLKGHRAVGGMRASIYNAMPIEGVKSLVNFMQDFARQYG", "output": "Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine."}]}
+{"id": "function_test_2785", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MATTSPAAPRPKSKSSSLLSTLFSRPLPLYVSAFLLRIVLLLYGLWQDANSPLKYTDIDYLVFTDAARFVSRGESPYARETYRYTPILAWLLLPTTWTAGAQWGPWAAKVINVAWFSFGKVLFAAADLVAGWLIEQVLVMGKDFPSSAAKGKEKDTEKTKEGGKKGPSVTASTGMDPSRARAFAAIWLLNPMVATISTRGSSEGLLGVLVMALLWAVLSRRITLAGLLLGFSVHFKIYPFIYAPAIVWWMDQERLSGVRAGGGGGGGGQKKTSSSFRKTLTRFLTLPRLLLAFTSLATFLSLNFLMYRLYGHPFLQETYLHHVTRIDHRHNFSPYNTQLYLSSASVSPSHSAAEPKFKIESLAFLPQLVLSTILIPLTLAKKDLPTSLLAQTFAFVTFNKVCTSQYFLWYLVLLPLYLPRSSFWTSKRMGLVALGLWVLGQALWLQQAYELEFLGRSTFLPGLWMASLGFFVVNCWILGVIVGDGGR", "output": "Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity (By similarity)."}]}
+{"id": "function_test_2786", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSVRILVVDDDRAVRESLRRSLSFNGYSVELAHDGVEALDMIASDRPDALVLDVMMPRLDGLEVCRQLRSTGDDLPILVLTARDSVSERVAGLDAGADDYLPKPFALEELLARMRALLRRTKPEDAAESMAMRFSDLTLDPVTREVNRGQRRISLTRTEFALLEMLIANPRRVLTRSRILEEVWGFDFPTSGNALEVYVGYLRRKTEADGEPRLIHTVRGVGYVLRETPP", "output": "Member of the two-component regulatory system MprB/MprA which contributes to maintaining a balance among several systems involved in stress resistance and is required for establishment and maintenance of persistent infection in the host. Functions as a transcriptional regulator that recognizes a 19-bp nucleotide motif comprizing two loosely conserved 8-bp direct DNA-binding motif repeats separated by a 3-bp spacer region (By similarity). MprB/MprA up-regulates expression of mprA and pepD."}]}
+{"id": "function_test_2787", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSQSNSDDSASSSTQQAGDGQDDVQQNIVWHAHTVSREDRESKLGQRGVVVWFTGLSGCGKSTIANELDRLLIDRGATCTLLDGDNVRHGLCAPPSVLKEEHGEDFAGRFGLGFGPTDREENIRRIGAVTELFASAGVIVLAAFVSPYQRDRDRVRNTIESSGRAGDFLEVFVDTPLEICKQRDPKGLYQKAIAGEIKNFTGISDPYDAPPSPEIHLKWREGQTPHDQASEIIREMEKRGVLGPAKG", "output": "Catalyzes the synthesis of activated sulfate."}]}
+{"id": "function_test_2788", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIVVTGAAGFIGSNLVRGLNRRGIQDIIAVDDLTDGDKFRNLVDCSIADYLDKDEFRERVRGGNLPALRAVLHQGACSDTTERNGRYMLDNNYRVTLELFEYCQAERVPFLYASSAAVYGGSSVYVEDPANEHPLNVYGYSKLLFDQVLRTRMDSLTAQVVGLRYFNVYGPHEQHKGRMASVAFHNMNQFLAEGHVRLFAGWDGYEDGGQSRDFISVEDVVAVNLHFLDNPDQSGVFNCGTGRAQPFNDVAAAVVNTLRAERGEAALPLAELVKKGLLRYIPFPDDLKGRYQSYTQADVSRLRATGFSAPMRDVQTGVSEYVRYWRALK", "output": "Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose."}]}
+{"id": "function_test_2789", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAAGPRTSVLLAFTLLCLPWPQEAGAFPAMPLSSLFANAVLRAQHLHQLAADTYKEFERTYIPEGQRYSIQNAQAAFCFSETIPAPTGKDEAQQRSDVELLRFSLLLIQSWLGPVQFLSRVFTNSLVFGTSDRVYEKLKDLEEGIQALMRELEDGSPRAGQILRQTYDKFDTNLRSDDALLKNYGLLSCFKKDLHKAETYLRVMKCRRFVESSCAF", "output": "Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues (By similarity)."}]}
+{"id": "function_test_2790", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLAKRIIPCLDVKEGRVVKGVNFIGLQDVGDPVEIAEAYNEAGADEIVFLDITATHEGRKTIIDVVEKTAAKVFIPLTVGGGISSVKDMYNLLRAGADKVSINSAAVRNPKLIEEGAEHFGSQCIVVAIDARKVAEGKWNVYVNGGRVDTGMDAIEWAKRVVKLGAGEILLTSMDADGTKSGYDLRLTEEISKSVSIPVIASGGCGHTDHIIEVFQKTTVDAALAASIFHYGEATVQSVKRKLRDANIEVRL", "output": "IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit."}]}
+{"id": "function_test_2791", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDTPDLQSRTSGIDTRLLRGELRQHEPMKRHVSWRAGGHAACFYQPADLEDLALFLRHWPKDEPVVMIGLGSNLLVRDGGLPGVVITLHAKLNDLSLVEQNESGGLIYAGAGVPCAKLARFAASHNLTGAEFLAGIPGTVGGALAMNAGCYGAETWDRVERVTTIDRSGIVRERTPEDYQVGYRHVELQRTPSSDTPDVWFTGGWFRLRPGKMESSRQAVRTLLTARIKTQPLGFPSAGSVFRNPPGDHAARLIEQCGLKGFRIGDAMVSTLHANFIVNCGHATASEIEAIIDTVQNAVHQATGIRLITEVRIIGQLGGSTQ", "output": "Cell wall formation."}]}
+{"id": "function_test_2792", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MQKKYFGTDGIRGKVGNSLINAEFMLKLGWAVGRVLANSHSATVLIGKDTRISGYMIESALQAGLSAAGVNIKLTGPMPTPAIAYLTHSVRADAGIVISASHNHYPDNGVKFFNKDGFKLSDELELAIEKQIDKPMKTVVADRLGKAARMNEAHGRYIEFCKSTFPSNLTLKGLKIVVDCANGAAYAVAPSIFHELGAEVVAIADDPDGFNINQTCGATDTAHLQEMVVKHNADVGIAFDGDGDRLIMVDHHGLRVDGDELLCIMAIDRFYLKENAPLGVVGTIMSNLGLEHTLKRHHIAFERSPVGDRYVLDLMQQKGWFLGGESSGHIVDLGFTTTGDGVITALQILRIMQQAEKPLADLKKVMVKHPQVLINVPIKGILDIAQNPNIKKAITEAEKQLNGAGRILLRPSGTEPVIRVMVEGSDEGIVRQTAEMLAAAVQQSTL", "output": "Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate."}]}
+{"id": "function_test_2793", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTAEEVDKESDPAIEDVKSDYDAIELGNENENENEVVSLDSMKAVISRASSELKHENDQGEERDLGSVEKDPILERYHAACKQGDMKTLREMVESKVIDLSNDYDPKERVSGLHWACINNRLSAVKYLAGAGAEVNFKGGELDATPLHWASKSGLVYIVDELLKAGADPNITDSQGYNLLHTSVFSSNIMLVIYVLFFVVDGKEDVDQPDPHQRTALQWATYQADALTVENLLKFNADVKNADDAGFTALHWGTVKGSIPVMDLLIKHGSDFFQTTNDGKNCFTIGKELYSIGSLEASLYKNGFDKNGFPLPQYFSASTGKMLTFFLPWVLIPLVFYIFSKITFFIALLINTIVLVISGLVLSRLVVPSYLLSKRHPILNSPLLAGILSGTIAIAFFIWFTKISILTFTEKPVGNIIMLGFFIGLITLFIGLMKSDPGYIPGTVDHDKVRETIKELLSLGKFDAKHFCVHTWIRIPLRSKYDRDSACLISAFDHFCPWVYNQIGLLNHKLFYMFVVLLEISVWWFLPLMMEYFDELEDYLENRKGKHFGDCHFLGDEDLCFGLHHDTFNFLLLCWVIFQAFWVLCLIAVQTVQMLKGVTDYEFVQINKKLKSNGTTTEDIFSSTPPELMSEELIAELDAPALDPRQVPQRTCFTVCCTLLGLDKLVTMIKSVLRLKSDEPSSRSSHLSALARIPTDYGWKQNLKDFWLLPDTSSPLWRRILLPPKDSHALLNGMEVDYYTLYTLPNATEELV", "output": "Palmitoyltransferase specific for casein kinase 1."}]}
+{"id": "function_test_2794", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLHPALALVPGEPAGVGPELCVRLVQQPRQDCRLVAFADPATLQAAAAALDLPLRLLPPEALPERPGDLPIQAHCHVHPTRFGHPDPANAPAVIAALCEAASHCVHGVLHGIVTGPVHKAVINQSGIHYTGTTELLAAQAECDVVMMLANPHLRVALVTTHLPLRDVPDAITAALLERCLRIVNTAMCGDFGIATPRIAVLGLNPHAGEEGYLGREELDVVIPVLQRLRAEGMVLLGPLSADTAFLPTKLIGYDAVVAMYHDQGLPVLKHSGFEQAVNITLGLPYPRVAVDHGTALDLAGRGVADPSSLFAATALCARLAASRALLSVRS", "output": "Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)."}]}
+{"id": "function_test_2795", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRALLSVLLLGLITFSTPSLALFGKDQFNNSQNNSFGSSNDSFVPVDQAFPFNFYQQDDKLMLDWQVRDGYYLYQERLSVSGENISLGELQMENGTPHKDEFFGDVHIYTTPLFVNVPLDEWQEGARVIVQYQGCAKAGFCYPPETRIIPIDAFTASIADSAVATKPTQSTANNNQTNATSPTASTSVSSNNTPAPVTEQDSLAANLADNWWTPLLFLALGVGLAFTPCVLPMYPILTSIVLGSGKLSQRRALGLSLVYVQGMALTYTLLGLVVASAGMQFQAAMQHPYVLIGLSILFVTLALSMFGVYTLQLPSSVQTWLNNLSNKQQGGSSAGVFAMGAISGLVCSPCTTAPLSGALLYVAQSGDLLTGGIALYALAMGMGIPLILVAVFGNKLLPKAGGWMDRVKTLFGFILLAAPIFLLERILPEMWSTALWSALGIAAFGWLYHIKNSLEFGGWKQSAIGIIAVLGLFASAQPALNYWFGNHETQAQQTTVSFTRIANVAELEEQLALAKAAGKPVMLDFYADWCVACKEFEKYTFHDPKVEAKLQDFVLLQADVTKNQVQDIELLKHMNVLGLPTIEFWDAKGEHVSNARLTGFMQAEPFLEHINRF", "output": "Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps."}]}
+{"id": "function_test_2796", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAKHERGLRFQPTGGVKSVQIPAGKKQRLSIERLSDDGRGIAFLEGKTWFVAGSLAGEEVEARVLNARGKVVEARTERVFVASDLRRAPACDYFGRCGGCSVQHVPHEEQLALKQRMLAEQLLRVANVVPDEWAAPLSGAELAYRRRARVAVRWDAKAKRLDVGFRAAASQDIVSIEECPVLVQALQPIMSQLPAMLKSFSKPQVLGHVELFSGSSTAVLLRHTAPLAEADLATLQAFCKTHGAQLWLHGEGEPQPASPGDTLGYRLEPWNLQLAWRPGDFIQVNAAVNTAMIEQALHWLAPAADERVMDLFCGLGNFALPLASLAKDVVAVEGVATMVERAAVNAMSNDLHNVRFFQADLSQPLTHADWAAEGFSAVLLDPPRDGAFEVVRQIRKTGAQRLLYVSCNPATLARDTVELVKQGYRLKRAGILDMFPQTAHVEAMALFEVSK", "output": "Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA."}]}
+{"id": "function_test_2797", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPRYKLTIEYDGAPFFGWQVQDTLPSVQGALEAAVKAMTGADLRVHGAGRTDAGVHARGQVAHVDIEKQFPPGRFRDGLNAHLRPHPIAVLEAEIVPDTFEARFSAVKRHYRYRIVNTRANLALDIGHAWRVPRRLDSDAMHAAARRLLGKHDFTTFRDTECQAKSPEKTLDQLDVLRDGREITIITSARSFLHSQVRSMVGSLVWVGEGRWTADDLSAALAARNRAACGIVAPPDGLYLVKVDY", "output": "Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs."}]}
+{"id": "function_test_2798", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKIEQTLSIIKPNIISNNFIGNIINRLEQAKLYIIASKMIKLSWKEAVSFYIEHKNKSFFSDLINFMISHPIIVQILEGENAIKRNREIMGNTNPKIALAGTLRSDFSNDIIKNGVHGSDSEESADREIKFFFKKDRIFSRI", "output": "Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate."}]}
+{"id": "function_test_2799", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSRLLRLGITGGIACGKSVVAGYLQRQYGVPIVDADVLARQVVAVGTPIYQAIVDRYGDGICRRDGTLDRSRLGEIVFAQPQERQWLEAQIHPAVVAEMEQAMATCDQPLMALVIPLLFEAHLEGLVDHIWVVATPPEQQLARLQQRDRLSAHAAGQRLASQLPLEEKIRRADTVLWNTGSLEELYRQVDQAFSLLGRGGKGG", "output": "Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A."}]}
+{"id": "function_test_2800", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIDRYILAIESSCDETSVAILKNEDQLLSNIIASQVESHKRFGGVVPEVASRHHVEVITLCIQDALQEAGITAGDLSAVAVTYGPGLVGALLVGMAAAKAFAWANHLPLIPVNHMAGHLMAAQSIADLQYPLLALLVSGGHTELVYVAAPGDYRIVGETRDDAVGEAYDKVGRVMGLTYPAGKEIDQLAHQGQDIYDFPRAMIKEDNLEFSFSGLKSAFINLHHNARQKGEQLRLEDLCASFQAAVLDILMVKTKKALAAYPVKTLVIAGGVAANQGLRERLKEDIKDINVVIPPLRLCGDNAGMIAYAAAVEYEKGHFAELDLNAKPSLAFEGLE", "output": "Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction."}]}
+{"id": "function_test_2801", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLREKSVELTRKIFADLGAWQIAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIVGGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMQMAERFKMPIITFIDTPGAYPGVGAEERGQSEAIARNLREMSRLSVPTICTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAHRNPEAMAASLKAQLLADLADLDVLSTEDLKNRRYQRLMSYGYA", "output": "Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA."}]}
+{"id": "function_test_2802", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MVECVKGRPNVLAIVLAGGEGKRLFPLTEDRAKPAVPFGGTYRLIDFVLSNLVNAGYLKIAVLTQYKSHSLDRHISVSWNVSGPTGQYIASVPAQQRLGKRWFTGSADAILQSLNLISDEKPDYVIVFGADHVYRMDPSQMVDEHIKSGKSVSVAGIRVPRHEATAFGCIQSDDEGNITEFLEKPADPPGTPDDPDVTFASMGNYVFTTEALVRALKDDSENEDSEHDMGGDIIPYFVDRGDAHVYDFSRNIVPGATERDKGYWRDVGTIDAFYECHMDLISVHPIFNLYNKEWPIHTTVEGNLPPAKFVQGGIAQSSMVAPGSIISAGTVRNSVLSTDVIVEEGATVEGAVLMPGVRIGKGAVVRHAILDKNVVVRDGELIGVDHDRDSQRFKVSAGGVVTVGKNQVV", "output": "Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc."}]}
+{"id": "function_test_2803", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSSSSPAGTARTIRKKVYDASLKAMFTLRPERIHGIIADGLGVLQMATPVNRAMGRVIGVNDPVLSQEVFGVTFPRPLGLAAGFDKNATAADTWTALGFGYAELGTVTASPQAGNPTPRLFRLPADRAILNRMGFNNAGAADVADNLRRRKSRDVIGINIGKTKVVPAEQAVDDYRRSASLLGDLADYLVVNVSSPNTPGLRDLQAVESLRPILAAVQESTSVPVLVKIAPDLSDEDVDAVADLAVELGLAGIVATNTTISREGLVTPAHEVAEMGAGGISGPPVAERALEVLRRLHARVGDQLVLIGVGGISTPEQAWERIAAGATLLQGYTGFIYGGPDWIRDIHLGLAEQVKAHGLSNISEAVGSGLPWKDSAV", "output": "Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor."}]}
+{"id": "function_test_2804", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSSASLLWCHSGVSTVRFGERIFTLVAGDLLFAPEEAQVADDSQGLVLNIRFETLNIMGPARRIHLGHVWNDRLTFEYSRSLFGKETLSPDIARLFTDRVPTPPLPAPRKARAVAQVLVSNPADQTSLEEFAEIQGVSARTLQRQFLKSTGYSFSEWRAAQRVCVAASLLAHDFSISVVANLVGFAATSSLTRAFRRHTGATPSTFTTGQIGMGSAGHPPRIPATTTFAEAHQDQQLWIYSGTATVTTPGYCRFMGQGDMVTIPAGTQTRIDVAAGSIAFPVPVGLDEWGMDLTRVVAVNNQQPKPLTILEQSEWSKLSEELLNTPVPVQM", "output": "Under iron limitation, RipA negatively controls the expression of the acn (aconitase), catA (catechol 1,2 dioxygenase), leuCD (isopropylmalate dehydratase), narKGHJI (nitrite/nitrate transporter and nitrate reductase), sdhCAB (succinate dehydrogenase), pta (phosphotransacetylase) and katA (catalase) genes. Binds to the consensus sequence in the promoter region."}]}
+{"id": "function_test_2805", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRDIVIIGHKAKTSGDFSLNDLPGSAGRMDILCRCVSSALFLSFGMRRDVNVHLLLLGEPEPGKIIRFEGLHLRYLNPDERSSGSLIQKALQKTVTEKDIRSTPGVWVRNGDLNTLLASFEGRTLFYLREDGEDIRGLDREIRDPVFILGDHMGVTEEEEKQLLEAGAKIISVGPISLHSNHCITLLHNELDRAEAERGEIPGGEKLRAGE", "output": "Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs."}]}
+{"id": "function_test_2806", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLLPDWKIRKEILIEPFSEESLQPAGYDLRVGREAFVKGKLIDVEKEGKVVIPPREYALILTLERIKLPDDVMGDMKIRSSLAREGVIGSFAWVDPGWDGNLTLMLYNASNEPVELRYGERFVQIAFIRLEGPARNPYRGNYQGSTRLAFSKRKKL", "output": "Catalyzes the deamination of dCTP to dUTP."}]}
+{"id": "function_test_2807", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNNSAFTFQTLHPDTIMDALFEQGIRVDSGLTPLNSYENRVYQFQDEDRRRFVVKFYRPERWTADQILEEHQFALQLVNDEVPVAAPVAFNGQTLLNHQGFYFAVFPSVGGRQFEADNIDQMEAVGRYLGRMHQTGRKQLFIHRPTIGLNEYLIEPRKLFEDATLIPSGLKAAFLKATDELIAAVTAHWREDFTVLRLHGDCHAGNILWRDGPMFVDLDDARNGPAIQDLWMLLNGDKAEQRMQLETIIEAYEEFSEFDTAEIGLIEPLRAMRLVYYLAWLMRRWADPAFPKNFPWLTGEDYWLRQTATFIEQAKVLQEPPLQLTPMY", "output": "A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response."}]}
+{"id": "function_test_2808", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSTPLQGIKVLDFTGVQSGPSCTQMLAWFGADVIKIERPGVGDVTRHQLRDIPDIDALYFTMLNSNKRSIELNTKTAEGKEVMEKLIREADILVENFHPGAIDHMGFTWEHIQEINPRLIFGSIKGFDECSPYVNVKAYENVAQAAGGAASTTGFWDGPPLVSAAALGDSNTGMHLLIGLLAALLHREKTGRGQRVTMSMQDAVLNLCRVKLRDQQRLDKLGYLEEYPQYPNGTFGDAVPRGGNAGGGGQPGWILKCKGWETDPNAYIYFTIQEQNWENTCKAIGKPDWITDPAYSTAHARQPHIFDIFAEIEKYTVTIDKHEAVAYLTQFDIPCAPVLSMKEISLDPSLRQSGSVVEVEQPLRGKYLTVGCPMKFSAFTPDIKAAPLLGEHTAAVLQELGYSDDEIAAMKQNHAI", "output": "Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate (By similarity)."}]}
+{"id": "function_test_2809", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAGQAGQQLPDDATLRHQILERLIMDQIILQMGQKMGVKITDEQLDQAIANIAKQNNMTMDQMRSRLAYDGLNYSTYRNQIRKEMIISEVRNNEVRRRITVLPQEVDALAKQIGTQNDASTELNLSHILIALPENPTSEQVNDAQRQAESIVEEARNGADFGKLAITYSADQQALKGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGQSQSISVTEVHARHILLKPSPIMNDQQARLKLEEIAADIKSGKTTFAAAAKEYSQDPGSANQGGDLGWATPDIFDPAFRDALTKLHKGQISAPVHSSFGWHLIELLDTRKVDKTDAAQKDRAYRMLMNRKFSEEAATWMQEQRASAYVKILSN", "output": "Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation."}]}
+{"id": "function_test_2810", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MMEILRGSPALSAFRINKLLARFQAANLQVHNIYAEYVHFADLNAPLNDSEQAQLTRLLQYGPALSSHTLAGKLLLVTPRPGTISPWSSKATDIAHNCGLQQIDRLERGVAYYIEASTLTAEQWRQVAAELHDRMMETVFSSLTDAEKLFIHHQPAPVSSVDLLGEGRQALIDANLRLGLALAEDEIDYLQEAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGKPQPKSLFKMIKNTFETTPDYVLSAYKDNAAVMEGSAVGRYFADHNTGRYDFHQEPAHILMKVETHNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIVTALDIMTEGPLGGAAFNNEFGRPALTGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNIRADHVQKGEIVVGAKLIVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERRCQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPLEIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGDATEEQHLSLHDNHFDNQPIDLPLDVLLGKTPKMTRDVQTLKAKGDALNRADITIADAVNRVLHLPTVAEKTFLVTIGDRTVTGMVARDQMVGPWQVPVADCAVTTASLDSYYGEAMSIGERAPVALLDFAASARLAVGEALTNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYDAVKAVGEELCPQLGLTIPVGKDSMSMKTRWQEGNEQREMTSPLSLVISAFARVEDVRHTLTPQLSTEDNALLLIDLGKGHNALGATALAQVYRQLGDKPADVRDVAQLKGFYDAMQVLVAARKLLAWHDRSDGGLLVTLAEMAFAGHCGVQVDIAALGDDHLAALFNEELGGVIQVRAEDRDAVETLLAQYGLADCVHYLGQALAGDRFVITANDRTVFSESRTTLRVWWAETTWQMQRLRDNPQCADQEHEAKANDADPGLNVKLSFDINEDIAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLGGRIGLGNFHALVACGGFSYGDVLGAGEGWAKSILFNHRVRDEFETFFHRPQTLALGVCNGCQMMSNLRELIPGSELWPRFVRNHSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRVEVRDDAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTENGRVTIMMPHPERVFRTVANSWHPENWGEDSPWMRIFRNARKQLG", "output": "Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate."}]}
+{"id": "function_test_2811", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MWRYISKQAYSRKFRNSHDSALLGFSQYSSSFGKTRPLQCLCEESTTNPNLGLSQNSIFSRISRKVRHLEGICEESSKNPHLGLSQNSLFSSVKGDFRVCGKRGSGSLGFLRSYGSAAEAIASTSEEDIDEIQELIEEMNKENEALKTNLQPKQPKTIGGMGVGKYNLLRRRQIKVETEAWEEAAKEYQELLMDMCEQKLAPNLPYMKSLFLGWFEPLRDAIAAEQKLCDEGKNRGAYAPFFDQLPAEMMAVITMHKLMGLLMTGGGTGSARVVQAASHIGEAIEHEARIHRFLEKTKKSNALSGDLEDTPGDIMKERERVRKKVKILMKKQKLQQVRKIVKQQDDEKPWGQDNLVKVGCRLIQILMETAYIQPPNDQLDDCPPDIRPAFVHTLKTVETMKGSRRYGVIQCDPLVRKGLDKTARHMVIPYMPMLVPPQSWLGYDKGAYLFLPSYIMRTHGAKQQREAVKRVPKKQLEPVFQALDTLGNTKWRLNRKVLGIVDRIWASGGRLADLVDREDVPLPEEPDAEDEAQIRKWKWKVKGVKKENCERHSQRCDIELKLAVARKMKDEDGFYYPHNLDFRGRAYPMHPYLNHLGSDLCRGILEFAEGRPLGKSGLRWLKIHLANVYGGGVDKLSYEGRVAFSENHVEDIFDSAERPLEGKRWWLGAEDPFQCLATCINIAEALRSPSPETAISYMPIHQDGSCNGLQHYAALGRDTLGAAAVNLVAGDKPADVYSGIAARVLDIMKRDAAKDPANDPNVMRARLLINQVDRKLVKQTVMTSVYGVTYIGARDQIKRRLKERGVIEDDNELFAAACYAAKTTLTALGEMFEAARSIMSWLGDCAKIIAMENHPVRWTTPLGLPVVQPYRKLGRHLIKTSLQILTLQRETDKVMVKRQRTAFPPNFVHSLDGSHMMMTAIACKESGLSFAGVHDSYWTHASDVDQMNKILREKFVELYDAPILENLLESFQQSFPDLQFPPLPERGDFDLREVLESPYFFN", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_2812", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQGPDIVRYIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAAREGLGQGPTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGAVCSAQEVEAIKAVTPTGFTCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPVAAYQAIKAEWAG", "output": "Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP)."}]}
+{"id": "function_test_2813", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRSRGVKYVSVRARLARSRVLAYLALTKPRVIELLLVTAIPAMLLADRGSANPLLILNTLLGGISAAAGANTFNCVADADIDKLMKRTSRRPLARAAVPPRNALVLGLALTAGSFFWLWWTTNLLSGLLALATVAFYVFVYTLLLKRRTSQNVVWGGAAGCMPVMIGWSAITDTIGWPALAMFAIIFFWTPPHTWALAMRYKDDYKVASVPMLPAVATERHVTKQILIYTWLTALSTLVLALATGWLYMAVAVVAGAWFLTMAHQLYVGVCAGEPVKPLRLFLQSNNYLAVVFCALAVDSVLALPTLF", "output": "Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group."}]}
+{"id": "function_test_2814", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLRWITAGESHGRALVAVVEGMVAGVEVTSTAIADQLARRRLGYGRGARMAFERDGVTVLSGVRHGVTLGGPIAIEIDNTEWPKWESVMAADPVDAAELEDSARNAPLTRPRPGHADYAGMLKYGFDDARPVLERASARETAARVAAGTIARQFLRQALGVEVLSHVISIGASARYDGPPPGSEDLTVIDASLVRAFDEQVEKSMIAEIEAAKKDGDTLGGVVEAVVLGLPVGLGSFTSGDDRLDSQLAAAVMGIQAIKGVEIGDGFATARRRGSCAHDEMYSGPGGVVRLTNRSGGLEGGMTNGQPLRVRAAMKPISTVPRALATVDLATGEEAIAIHQRSDVCAVPAAGVVVETMVALVLARAALRKFGGDSLGETRRNLAAYQRAVADREAPVAQYCGESGIGG", "output": "Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system."}]}
+{"id": "function_test_2815", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MVIGLTGGIASGKSTVVDFLISEGYQVIDADKVVRQLQEPGGKLYKAIVETYGLDFIADNGQLNREKLGALVFSDSKEREKLSNLQDEIIRTELYDRRDDLLKKMTDKSVSKNFDSKSQGKNLSVNKPIFMDIPLLIEYNYTGFDEIWLVSLPEKIQLERLMARNKFTEEEAKKRISSQMPLSEKQKVADVILDNFGTIEALKKQIQRELARIEEQK", "output": "Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A."}]}
+{"id": "function_test_2816", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKKTALLNAPLSQVIATLGHTDSLTICDAGLPIPKQIERVDLALSAGVPSFLQTFHAVVTEMFVERAIIAEEIKEKNPKILTALLNSLAQLEQQQGNQIEVQYVSHDMFKTYTHASKAIVRSGECSPYANIILYSGVPF", "output": "Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose."}]}
+{"id": "function_test_2817", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MARIGDGGDLLKCSFCGKSQKQVKKLIAGPGVYICDECIDLCNEIIEEELAETSEVRWEELPKPREIYEFLESYVVGQEAAKKALSVAVYNHYKRVQAGENGGAQGREDAIELAKSNILLLGPTGSGKTLLAQTLARMLNVPFAIADATALTEAGYVGEDVENILLKLIQAADYDVKKAETGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPHQEFIQIDTTNVLFIVGGAFAGLEKIIEGRAGAKGIGFGAQIRSKREIESKDQFEQVMPEDLVKFGMIPEFIGRLPVITSVHNLDREALLQILVEPRNALVKQYERLFELDGVELDFERGALEAIADQAILRQTGARGLRAIMEEVLQGVMYEVPSRKDVARVVITADVVLSNVNPTLIPRDSRGRGPGEQKTA", "output": "ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP."}]}
+{"id": "function_test_2818", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAQQMGNQPLIVLSEDSQRTSGEDAQSMNITAGKAVAESVRTTLGPKGMDKMLVDSSGEVVVTNDGVTILKEMDIEHPAANMIVEVAETQETEVGDGTTTSVVVSGELLSEAETLLEQDIHATTLAQGYRQAAEKAKELLDDAAIDVSADDTETLEKIAATAMTGKGAENAKGVLSDLVVRAVQSVADDNDVDTDNVKVEKVTGGAIENSELIEGVIVDKERVSENMPYAVEDANIALVDDGLEVQETEIDTEVNVTDPDQLQNFLDQEEEQLKEMVDALKDAGANVVFADSGIDDMAQHYLAKEGILAVRRAKSDDFTRLSRATGATPVSNVNDIEAADLGAAGSVAQKDIGGDERIFVEDVEEAKSVTLILRGGTEHVVDEVERAIEDSLGVVRVTLEDGQVMPGGGAPETELAMQLRDFADSVGGREQLAVEAFADALEVIPRTLAENAGHDPIDSLVDLRSQHDGGDTEAGLDAYNGDVIDMESEGIVEPLRVKTQAIESATEAATMILRIDDVIAAGDLAGGQVGDDDGDDGPAGGPGGMGGGMGGMGGMGGMGGAM", "output": "Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity."}]}
+{"id": "function_test_2819", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MMETQLYIGIMSGTSMDGADAVLIRMDGGKWLGAEGHAFTPYPGRLRRKLLDLQDTGADELHRSRMLSQELSRLYAQTAAELLCSQNLAPSDITALGCHGQTVRHAPEHSYSVQLADLPLLAERTQIFTVGDFRSRDLAAGGQGAPLVPAFHEALFRDDRETRAVLNIGGIANISVLPPDAPAFGFDTGPGNMLMDAWMQAHWQLPYDKNGAKAAQGNILPQLLDRLLAHPYFAQPHPKSTGRELFALNWLETYLDGGENRYDVLRTLSRFTAQTVFDAVSHAAADARQMYICGGGIRNPVLMADLAECFGTRVSLHSTAELNLDPQWVEAAAFAWMAACWVNRIPGSPHKATGASKPCILGAGYYY", "output": "Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling."}]}
+{"id": "function_test_2820", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQVFADIAVLREQIKQIKREGRRVAFVPTMGNLHEGHLTLVRKARELADVVVVSIFVNPMQFDRAEDLKNYPRTLEEDLSKLNGEGVDLVLTPTPETMYPQGLDKQTFVEVPGLSYMLEGASRPGHFRGVATIVTKLFNIVQPDVACFGEKDFQQLAVIRQMVEDLCMDIEIVGVATVRELDGLAMSSRNNLLTLDERQRAPVLARTMRWISSAIRGGRDDYPSIIEDAVDQLRAADLEPDEIFIRDARTLLPISSESKQAVILMSAFLGKVRLIDNQVLDLQTDTKASSEEE", "output": "Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate."}]}
+{"id": "function_test_2821", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTLPANQSPEMVILCNELGEATGTAPKSEIHHSDTPLHLAFSVYIFNGDNKLLVTRRASDKITWPGVLSNSCCGHPQPGEPLTEAIERRVHEELRIRADDIRLVLPEFSYRASMTNGITENELCPVFAAHCKTSGVNPDLNEVSAWEWVHWQWFFESVQAERLLVSPWCRAQVDLLAPLGANPSQWPVAEERRLPKAARTKIDVQLKVS", "output": "Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)."}]}
+{"id": "function_test_2822", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTSLLDKYLRNISGKGQQSLASVAYLAALDHLLHSFPSIGQSIVQELKSQRSRLKMIASENFSSLSVQLAMGNLLTDKYCEGSPFKRFYSCCENVDAIEWECVETAKELFGAESACVQPHSGADANLLAIMSIITQKIQSPAVQRLGYKTINDLPEQEYEALKAEMSQYKCLGPSLNSGGHLTHGTVRINVMSKLMHCLPYEVNLDTELFDYDVIAKIAKEHRPTVLIAGYSSYSRRLNFATLKQIAEDCGAVLWVDMAHFAGLVAGGVFIGEENPIPYADIVTTTTHKTLRGPRGGLVLAKKEYSDTLNKACPLMMGGPLPHVIAAKAVALKEAMTINFRKYAHQVVENARTLAEIFQRNGLRLLTGGTDNHMLIIDLTSLGVPGRIAEDMLTSVGIAVNRNSIPSDASGQWKTSGIRLGTPALTTLGMGSAEMEEVANIIAKVLRNITVRRNAEGSSSKSEGVLSEEIAQEARQRVADLLGRFPLYPEIDLETLV", "output": "Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism."}]}
+{"id": "function_test_2823", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLDIRLIRKEPKECEARLQKKDPSISLERLLDLDKNVRQLKADSESLLARRKALSGQIHKAKVANEDATPLIQGVNAIADQLVAFEKTLQEQEALLLDLMARLPNYPDEDVPVSPDKSGNKIIKSHGEIPTFTFPPKHHVQLNEKLQILDFKLPAKTSGSGWPAYKNEGVLLEWALLTYLLNKQQAHGFQLWLPPLLVKRDILFGSGQIPKFDGQYYRVEDGEQSLFLIPTAEVVLNGFHSQEILNEQDLPLYYAAFTPCFRREAGAGGSHERGLVRVHQFHKVEMFAFTTPEQEEIAYQKMIGIVEEILSELQLPYQLSLLSTGDMSFTAKKTIDAEVWLPGQQAFYEVSSISKCGDFQSRRSETRYRDAQGKLHFVNTLNGSGLATPRLLVAILENYQQEDGSVVIPHALRPYMNNQEILLPKTDR", "output": "Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)."}]}
+{"id": "function_test_2824", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSFPYFISPEQAMRERSELARKGIARGRSVVALAYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKPPELYRITYDGSINDEPHFMVMGGTTESIANALKESYAENASLTDALGIAVAALRAGSADAAGSDQPTLGVASLEVAVLDANRPRRAFRRIIGSGLEALLREKDSKGSKGAQNPKGARDSKNSKSYGESTD", "output": "Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation."}]}
+{"id": "function_test_2825", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPELPWVEKYRPKKLSEIVNQEEAIEKVRAWIESWLHGHPPKKKALLLAGPPGSGKTTTVYALANEYNFEVIELNASDERTYEKISRYVQAAYTMDILGKRRKIIFLDEADNIEPSGAKEIAKLIDKAKNPIIMAANKYWEVPKEIREKAELVEYKRLTQRDVMNALIRILKREGITVPKEILLEIAKRSSGDLRAAINDLQTVVVGGYEDATQVLAYRDVEKTVFQALGLVFGSDNAKRAKMAMWNLDMSPDEFLLWVDENIPHLYLNPEEIAQAYDAISRADIYLGRAARTGNYSLWKYAIDMMTAGVAVAGRKRRGFVKFYPPNTLKILAESKEEREIRESIIKKIIREMHMSRLQAIETMKIIREIFENNLDLAAHFTVFLGLSEKEVEFLAGKEKAGTIWGKALALRRKLKELGIREEEKPKVEIEEEEEEEEKTEEEKEEIEEKPEEEKEEEKKEKEKPKKGKQATLFDFLKK", "output": "Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA. The complex possesses DNA-dependent ATPase activity which is further stimulated by PCNA."}]}
+{"id": "function_test_2826", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIKVAAAGGGTGGHLYPLLAILETLAKRVDVKVLFFAVKGKIDERVVRKDHPEFETVSIDVRGLLRPLHHPKNLWRTLKIGIATIEVKKHLKRFKPDLVVLTGGYISGVVGLAAKDLGIPIFVHEQNVVPGLAVKVLSQYAKKVFVSFERTRDYLREWQDKIVVTGCPVRETEKEAPLKDFVLVLGGSLGSEAINELMEKVYPELQETQFVHSTGSDDWTERLSVFPNVTALTYIDPMGAYWKKAIASISRAGASTIAEMMYYGVPGILIPWESSAESHQLENALEAERLGYAIVIRENEASPRKIIESIDKVVKKGKIEKMKENPASKISKEILGEIM", "output": "Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II)."}]}
+{"id": "function_test_2827", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPREIITLQVGQCGNQIGMEFWKQLCLEHGISKDGILEDFATQGGDRKDVFFYQADDEHYIPRALLIDLEPRVINSIQNSEYRNLYNHENVFVADHGGGAGNNWASGYHQGEQVEEDIMDMIDREADGSDSLEGFVLCHSIAGGTGSGMGSYLLEALNDRYSKKLVQTYSVFPNQMETSDVVVQPYNSLLTLKRLTLNADCVVVLDNTALNRIAVDRLHIPNPTFAQTNSLVSTVMSASTTTLRYPGYMNNDLVGLVASLIPTPRCHFLMTGYTPLTVERQANAIRKTTVLDVMRRLLQAKNIMVSSYARTKEASQAKYISILNIIQGEVDPTQVHKSLQRIRERKLANFIEWGPASIQVALSRKSPYVQTAHRVSGLMLASHTSIRHLFSKCISQYEKLRKKQAFLDNYRKFPMFADNDLSEFDESREIVQNLVDEYKACESADYIKWGMEDRGKQVSGEGNTSGTVDSRVGAS", "output": "Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles, suggesting that it is involved in the minus-end nucleation of microtubule assembly."}]}
+{"id": "function_test_2828", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MARRIVVESYPYPRVEDLQVELVERKGLGHPDTICDAAAEAVSRELSKYYLERFGKILHHNVDKVLLVGGQAAPRLGGGEVLQPIYILVSGRVTTEVRTGGGVESVPVGPIILRAVKNYIRENFRFLDPEEHVIVDYRVGRGSVDLVGIFEAEDKVPLANDTSIGSGHAPLSTLERLVLETERILNSRETKERLPAVGEDVKVMGVRDGKSITLTVAMAVVSSQVGSVSDYLAVKEEAESLILDLASRIAPDYDVRVNINTGDIPEKKILYLTVTGTSAEHGDDGATGRGNRVNGLITPMRPMSMEAAAGKNPVNHVGKIYNVVANEMAALIHREVKGVEEVYVKLVSQIGKPIDRPRIVDVKVRMEGGREVTADAKREIEAIANSVLDGITGYTEKLVRGDITVY", "output": "Catalyzes the formation of S-adenosylmethionine from methionine and ATP."}]}
+{"id": "function_test_2829", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MERIKELRDLMSQSRTREILTKTTVDHMAIIKKYTSGRQEKNPALRMKWMMAMKYPITADKRIMEMIPERNEQGQTLWSKTNDAGSDRVMVSPLAVTWWNRNGPTTSTVHYPKVYKTYFEKVERLKHGTFGPVHFRNQVKIRRRVDMNPGHADLSAKEAQDVIMEVVFPNEVGARILTSESQLTITKEKREELKNCNIAPLMVAYMLERELVRKTRFLPVAGGTSSVYIEVLHLTQGTCWEQMYTPGGEVRNDDVDQSLIIAARNIVRRATVSADPLASLLEMCHSTQIGGVRMVDILKQNPTEEQAVDICKAAMGLKISSSFSFGGFTFKRTKGFSVKREEEVLTGNLQTLKIKVHEGYEEFTMVGRRATAILRKATRRMIQLIVSGRDEQSIAEAIIVAMVFSQEDCMIKAVRGDLNFVNRANQRLNPMHQLLRHFQKDAKVLFQNWGIEPIDNVMGMIGILPDMTPSTEMSLRGVRVSKMGVDEYSSTERVVVSIDRFLRVRDQRGNVLLSPEEVSETQGMEKLTITYSSSMMWEINGPESVLVNTYQWIIRNWETVKIQWSQEPTMLYNKMEFEPFQSLVPKAARSQYSGFVRTLFQQMRDVLGTFDTVQIIKLLPFAAAPPEQSRMQFSSLTVNVRGSGMRILVRGNSPAFNYNKTTKRLTILGKDA", "output": "Plays an essential role in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNAs are used to generate primers for viral transcription. Binds the cap of the target pre-RNA which is subsequently cleaved after 10-13 nucleotides by PA. Plays a role in the initiation of the viral genome replication and modulates the activity of the ribonucleoprotein (RNP) complex. In addition, participates in the inhibition of type I interferon induction through interaction with the host mitochondrial antiviral signaling protein MAVS."}]}
+{"id": "function_test_2830", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSLIVTRFAPSPTGYLHIGGLRTAIFNYLFARANQGKFFLRIEDTDLSRNSIEAANAIVEAFKWVGLEHDGEILYQSKRFEIYKEYIQKLLDEDKAYYCYMSKEELDALREEQKARKETPRYDNRYRDFKGTPPKGIEPVVRIKVPQNEVIGFNDGVKGEVKVNTNEIDDFIIARSDGTPTYNFVVTIDDALMGITDVIRGDDHLSNTPKQIVLYKALNFKIPNFFHVPMILNEEGQKLSKRHGATNVMDYQEMGYLKEALVNFLARLGWSYQDKEVFSMQELLEWFNPKDLNSSPSCFSWHKLNWLNAHYLKNQSVQELLKLLKPFSFSDLSHLNPAQLDRLLDALKERSQTLKELALKIDEVLTAPIEYEEKVFKKLNQALVMPLLEKFKLALDKTDFNDESALENAMHQIIEEEKIKAGHFMQPLRLALLGKGGGIGLKEALFILGKAESIKRIEEFLKN", "output": "Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)."}]}
+{"id": "function_test_2831", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGSIEPPNASSCLVYQTITEFADFPDHDQKLWWHSTAPMFAEMLKVAGYDIHSRYKALGLYQKFIIPFLGVYPTKTNDRWLSILTRYGTPFELSLNCTHSVVRYTFEPINAATGSLKDPFNTHAIWDALDTLIPLQKGIDLEFFAHLKRDLTVNDQDTAYLLEKKKVGGQIRTQNKLALDLKGGEFVLKAYIYPALKSLATGKPVQELMFDSVHRLSHQYPTLAAPLRKLEEYVHSRGTSSTASPRLISCDLCDPRQSRIKIYLLELNVSLESMEDLWTLGGRRNDTQTLAGLEMIRELWDLINLPTGILSYPEPYLKLGEVPNEQLPLMANYTLHHDDPMPEPQVYFTTFGMNDGRVTDGLATFFRRHGYTHMLQTYRDSLRAYYPHVDHDTVNYLHAYISFSYRKGSPYLSVYLQSFETGDWPISSFGAPILEPVSKKMCRGHPVSFEVPLTKQQVVASE", "output": "Tryptophan dimethylallyltransferase; part of the gene cluster that mediates the biosynthesis of isofumigaclavines, fungal ergot alkaloids . The tryptophan dimethylallyltransferase ifgA catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4-dimethylallyl-L-tryptophan . The second step is catalyzed by the methyltransferase ifgB that methylates 4-dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of N-methyl-dimethylallyl-L-tryptophan . The catalase ifgD and the FAD-dependent oxidoreductase ifgC then transform N-methyl-dimethylallyl-L-tryptophan to chanoclavine-I which is further oxidized by ifgE in the presence of NAD(+), resulting in the formation of chanoclavine-I aldehyde . The chanoclavine-I aldehyde reductases ifgG and/or fgaOx3 reduce chanoclavine-I aldehyde to dihydrochanoclavine-I aldehyde that spontaneously dehydrates to form 6,8-dimethyl-6,7-didehydroergoline . The festuclavine dehydrogenases ifgF1 and/or ifgF2 then catalyze the reduction of 6,8-dimethyl-6,7-didehydroergoline to form festuclavine . Hydrolysis of festuclavine by a yet undetermined cytochrome P450 monooxygenase (called ifgH) then leads to the formation of isofumigaclavine B which is in turn acetylated by ifgI to isofumigaclavine A . Penicillium roqueforti has interestingly at least two sets of genes for the consumption of chanoclavine-I aldehyde on three different loci, the OYEs ifgG/fgaOx3 and the festuclavine synthase homologs ifgF1/ifgF2 . The reason for the duplication of these genes is unclear, probably to ensure the conversion of chanoclavine-I aldehyde by differential gene expression under various environmental conditions ."}]}
+{"id": "function_test_2832", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVHVSNRSIQGMNILFSSWAVVLMVMGITLDKWVELISEDERAKMNHSPWMMCCPALWPEDDLKVVRIMMTSSLGLSFLLNLILGMKFTYLIPQNKYIQLFTTILSFFSGISLLWALILYHNKLKQGQSMHFSNYRITWIMYTAYLNVFFLSVCGVLSLLECKLSTSSCTCLNIHKSDNECKESENSIEDISLPECTAMPRSIVRAHTVNSLNKKVQTRHVTWAL", "output": "Probably inhibits protein phosphatase 1 (PP1) in sperm via binding to catalytic subunit PPP1CC."}]}
+{"id": "function_test_2833", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRLSVTALLVTLALCYYEANAIVCPTFAADLTEFFYFPDLLYRLSLAKYNAPPEAVAAKMEVKQCTDRFSVKNRLIITNILGKILLNCTVTDVKAVLNPSSA", "output": "May bind androgens and other steroids. May be under transcriptional regulation of steroid hormones (By similarity)."}]}
+{"id": "function_test_2834", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDSARALIARGWGVSLVSRCLRVSRAQLHVILRRTDDWMDGRRSRHTDDTDVLLRIHHVIGELPTYGYRRVWALLRRQAELDGMPAINAKRVYRIMRQNALLLERKPAVPPSKRAHTGRVAVKESNQRWCSDGFEFCCDNGERLRVTFALDCCDREALHWAVTTGGFNSETVQDVMLGAVERRFGNDLPSSPVEWLTDNGSCYRANETRQFARMLGLEPKNTAVRSPESNGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREYLRQRACNGLSDNRCLEI", "output": "Involved in the transposition of the insertion sequence IS2."}]}
+{"id": "function_test_2835", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MHDYIKERTIKIGKYIVETKKTVRVIAKEFGVSKSTVHKDLTERLPEINPDLANEVKEILDYHKSIRHLRGGEATKLKYKKDEILEGEPVQQS", "output": "This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K)."}]}
+{"id": "function_test_2836", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLEHLSSLPTQMDYKGQKLAEQMFQGIILFSAIVGFIYGYLAEQFGWTVYIVMAGFAFSCLLTLPPWPIYRRHPLKWLPVQDSSTEDKKPGERKVKRHAKNN", "output": "Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). Dispensable for SPC enzymatic activity (By similarity)."}]}
+{"id": "function_test_2837", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSVTLHTSLGDIKVEIFCDSVPLASENFLALCASNYYNNTIFHRNIKGFMIQGGDPTNTGRGGESIWKKQFKDEFPSHLKHNTRGILSMANSGPDTNGSQFFITYGKHRSLNKVYTVFGKIIAGIEVLDLMEKVPVDDKDLPLNEIILKSVTIHANPIANQ", "output": "PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)."}]}
+{"id": "function_test_2838", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAAPRHHHLALAVALALLVVTAAAADEGGPRGRRVLVLVDDLAVRSSHSAFFASLQGRGFDLDFRLADDPKLSLHRYGQYLYDGLVLFAPSTPRFGGSVDQNSILEFIDAGHDMILAADSSASDLIRGIATECGVDFDEDPEAMVIDHINYAATDAEGDHTLIAGDDLIQSDVILGSKKIEAPVLFRGIGHAVNPSNSLVLKVLSASPSAYSANPKSKLASPPSLTGSAISLVSVMQARNNARVLISGSLDLFSNRFLKSGVQKAGSKIRHEKAGNEQFVTETSKWVFHERGHLKAVNVKHNKVGETNEPGMYRINDDLEYSVEIYEWSGTSWKPYVADDVQVQFYMMSPYVLKTLSTDKKGVFSTSFKVPDVYGVFQFKVEYQRLGYTGLSLSKQIPVRPYRHNEYERFITSAYPYYAASFSTMGAFFIFSFVYLYHK", "output": "Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity."}]}
+{"id": "function_test_2839", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSVPAFIDITEEDQASELRSYLKSKGAEISEENSEGGLHVDLAQIIEACDVCLKDDDKDVESVMNSIVSLLLILETEKQEALIESLCEKLVKFREGERPSLRMQLLSNLFHGMDENTPVRHTVYCSLIKVAATCNAITFMPTDLDQVRKWIVDWNLNTEKKHTLLRLVYEALVDCKKSEAAAKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNTYLFDHLLALKPVRFLEGELIHDLLTIFVSAKLISYVKFYQSNKDFIESLGLSHEQNMSKMRLLTFMGMAVEMKEISFETMQQELQIGAEDVEAFVIDAVRTKMVYSKIDQTQRKVVVSHSTHRTFGKQQWQQLYDTLCSWKQNLSTVKSSLQTLSPTA", "output": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation."}]}
+{"id": "function_test_2840", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MANNSPALTGNSQPQHQAAAAVTQQQQQCGGGGGATKPAVSGKQGNVLPLWGNEKTMNLNPMILTNILSSPYFKVQLYELKTYHEVVDEIYFKVTHVEPWEKGSRKTAGQTGMCGGVRGVGTGGIVSTAFCLLYKLFTLKLTRKQVMGLITHTDSPYIRALGFMYIRYTQPPTDLWDWFESFLDDEEDLDVKAGGGCVMTIGEMLRSFLTKLEWFSTLFPRIPVPVQKNIDQQIKTRPRKIKKDGKEGIEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLDRRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGSDRERDRERSRERSKEQRSRGDGEEKKHKEDKEDRRHRDDKKESKKKHSRSRSRERKHRSRSRNAGKRSRSRSKDKSSRHKNESKEKANKRSRSGSQGRTGSVEKRKREHSPSREKSRKRSRSQDRSHKREHNDSKDQSDRQDHQSSQSGEPESQEKEHKSKDETV", "output": "May be required for pre-mRNA splicing."}]}
+{"id": "function_test_2841", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGRGRSEIKRIENPTQRQSTFYKRRDGLFKKARELAVLCDADLLLLLFSASGKLYHFLSPTVPSVREFVERYEATTHTKVWADIRQERRAELEKVGSMCDLLEKQLRFMTVDDGEEYTVPSLEALEHNLEAAMRKVRSEKDRKIGGEICYLQNIIRGRQEERYGLCDKIAHAQTLKDVECGSTSLSNGLDLKLGFN", "output": "Probable transcription factor."}]}
+{"id": "function_test_2842", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSPTQWDFPVELCCRPMAFVTLTGLDVVYNAVHRAVWDAFCANRRADRVPISFKVLPGDHEYPKCRPKRTSYEWYIPKGILKTGWMNKHLNLVPALVVVFYELDWDEPQWKEKQSECATRVEIVRQSLQGRNTKVAVVLIQKKTPLPPGEDVIASERAAALCNACELSGKSLFVLPHTDHLVGYIIRLENAFYEHAQTYYYTEIRRVKSHKEFLNKTTHQLLFVRHQFKIAFFSELKQDTQNALKNYRTAYNLVHELRAHETNILEIKTMAGFINYKICRLCFQHNTPLDAIAQFRKHIDLCKKKIGSAELAFEHAAWMSKQFQAFGDLFDEAIKLGLTAIQTQNPGFYYQQAAYYAQERKQLAKALCNHEASVTYPNPDPLETQAGVLDFYGQRSWRQGVLSFDLSDPEKEKVGILAIQLKERSVVHSEVIITLLSNAVAQFKKYKCPRMKSHLMVQMGEEYYYAKDYTKALKLLDYVMCDYRSEGWWTLLTSILTTALKCSYLMAQLKDYITYSLELLGRASTLKDDQKSRIEKNLINVLMNESPDPEPDCDILAVKTAQKLWVDRISLAGSNVFTIGVQDFVPFVQCKAKFHAPSFHVDVPVQFDVYLKADCPHPIRFSKLCISFNNQEYNQFCVIEEASKASDVLENLTQGKMCLVPGKTRKFLFKFVAKTEDVGKKIEITSVDLVLGSEAGRCVVLNWQGGGGDAASAQEALQASRSFKRRPRLPDSEVHWDGIVIQASTMIISRVPNISVHLRHDPPALTNEMYCLVVTVQSHEKSPIRDVKLTAGLKPGQDANLTQKTHVTLHGTELCDESYPALLTDIPIGDLQPGEQLEKAVYVRCGTVGSRMFLVYVSYLINTAIEGKETVCKCHKDETVTIETVFPFDVAVKFVSTKFEHLERVYADIPFLLMTDLLSASPWALTIVSSELQLAPSMTPVDQLESQVDRVVLQTGESASECFCLRCPSVGNVEGGVATGHYVISWKRTSATDGVPVISTVITLPHVIVENIPLHVNADLPSFGRVRESLPVRYHLQNKTDLVQDVEISVEPSDAFMFSGLKQIRLRILPGTEQEMLYNFYPLMAGYQQLPSLNINLLRFPNFTNQLLRRFIPTSIFVKPQGRLVDDASIAAA", "output": "Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage."}]}
+{"id": "function_test_2843", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGRKDSSNTKLPVDQYRKQIGKQDYKKTKPILRATKLKAEAKKTAIGIKEVGLMLAAILALLLAFYAFFYLRLSTNIDSDLDLDED", "output": "May play a role in cell growth and maintenance of cell morphology."}]}
+{"id": "function_test_2844", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTLAGIFIGGGLGAMLRFWLGNVITAKTKGLSLPIGILTVNILGALGLGIFTGLHVANASVSLIIGTGFFGAFTTFSTFSVETIQLLMAKRVKESILYIVLTLCGSLFAFWCGWTITI", "output": "Important for reducing fluoride concentration in the cell, thus reducing its toxicity."}]}
+{"id": "function_test_2845", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNRSFHFLIKYIYIHVLLVFYFHIKQQAIMPFFIFFFSSFDGLSFDLRVVAFLAKHVFVGVCSPFFVVGFFGSSRVVVTEWLSKLVLPPPPVSITQVFSLSRKRGEFSSGYILIINPYKSFLRSLLDFSIFNNTAKNKSSTFTLNLEDVSK", "output": "May be involved in cell wall organization and biogenesis."}]}
+{"id": "function_test_2846", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSTLLYLHGFNSSPRSAKASLLKNWLAEHHPDVEMIIPQLPPYPSDAAELLESIVLEHGGDSLGIVGSSLGGYYATWLSQCFMLPAVVVNPAVRPFELLTDYLGQNENPYTGQQYVLESRHIYDLKVMQIDPLEAPDLIWLLQQTGDEVLDYRQAVAYYASCRQTVIEGGNHAFTGFEDYFNPIVDFLGLHHL", "output": "Displays esterase activity toward palmitoyl-CoA and pNP-butyrate."}]}
+{"id": "function_test_2847", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MASVSISCPSCSATDGVVRNGKSTAGHQRYLCSHCRKTWQLQFTYTASQPGTHQKIIDMAMNGVGCRATARIMGVGLNTIFRHLKNSGRSR", "output": "Absolutely required for transposition of IS1."}]}
+{"id": "function_test_2848", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKLSMKSLAALLMMLNGAVMASENVNTPENRQFLKQQENLSRQLREKPDHQLKAWAEKQVLENPLQRSDNHFLDELVRKQQASQDGKPRQGALYFVSFSIPEEGLKRMLGETRHFGIPATLRGMVNNDLKTTAEAVLSLVKDGATDGVQIDPTLFSQYGIRTVPALVVFCSQGYDIIRGNLRVGQALEKVAATGDCRQVAHDLLAGKGDSGK", "output": "Essential for F plasmid conjugative transfer, participates in F-pilus assembly."}]}
+{"id": "function_test_2849", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEGRKSEDEKNEAALACDVFESSNAKLPKNVFRSSFTWYCYEVINRSAFHIWLLLCLTLIVGWKVFSGIGGRRPSDSNMDGPQTKHKRNPGFLRRHSTIVILVISLAVSFSWEAFKMYRERTFGKQITQFAKEIIKSAPSTDMESWDRVAADFNSYMYENKLWNTEYFFC", "output": "May be involved in cell wall organization and biogenesis."}]}
+{"id": "function_test_2850", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLIIKRSVAIIAILFSPLSTASNLTSQLHNFFSAQLAGVSDEVRVSIRTAPNLLPPCEQPLLSMSNNSRLWGNVNVLARCGNDKRYLQVNVQATGNYVVAAMPIARGGKLEAGNVKLKRGRLDTLPPRTVLDINQLVDAISLRDLSPDQPIQLTQFRQAWRVKAGQRVNVIASGDGFSANAEGQALNNAAVAQNARVRMVSGQVVSGVVDADGNILINL", "output": "Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly."}]}
+{"id": "function_test_2851", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVSPDMIRNVVGIVGNVISFGLFLSPVPTFWQIIKNKNKNKKKMEVVLAAEALFMVSPDMIRNVVGIVGNVISFGLFLSPVPTFWQIIKNKNKNKKKMEVVLAAEALFMAAVALGVLLGVHTHQRRSLIVGILCVIFDTIMYSSPLTVMSQVVKTKSVEYMPLLLSVVSFLNGLYWTSYTLIRFDIFITIPNGLGVLFAAVQLILYVIYYRTTPKKQNKNLELPTVTPVAKDTSVGPISKDNDLNGSTASHVTIDITIQP", "output": "Mediates both low-affinity uptake and efflux of sugar across the plasma membrane."}]}
+{"id": "function_test_2852", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTINYHKEIMTSHPWTFFLLLFKWKGSIWKAVYMETIIFLICYGIISVIYKTAMGESSQRTFESLVRYFDKRLSYIPLEFVLGFFVTTVVNRWTKLYQTIGFIDNVGLMANCYIRGATEKARIYRRNIMRYCELVQILVFRDMSMRTRRRFPTMETVVAAGFMNKHELELYNSYDTKYNSKLGTKYWIPANWALCMTYKARKDGYIESDYFKAQMEGEIRTWRTNIEWVCNYDWVPLPLMYPQLVCLAVNLYFLVSIIARQLVIEKHKMVDEVDVYFPVMTFLQFIFYMGWLKVIDVMLNPFGEDDDDFETNALIDRNITMGLMIADNPMSTPELRKDPFYDEVDVPLLYSEESSNIPNHHYHGSVSEVRLEQKGNAPVMMMPHSQSAANLRRMMSFKSVDEDEKDINAFSMSHDDARMRNWREVSLDSSFLADLNENKEWKIPTNPQKF", "output": "Forms chloride channels."}]}
+{"id": "function_test_2853", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRGEIDEANLAPETSLINKENQDSSATITTTLLLTTFVAVSGSFVFGSAIGYSSPVQSDLTKELNLSVAEYSLFGSILTIGAMIGAAMSGRIADMIGRRATMGFSEMFCILGWLAIYLSKVAIWLDVGRFLVGYGMGVFSFVVPVYIAEITPKGLRGGFTTVHQLLICLGVSVTYLLGSFIGWRILALIGMIPCVVQMMGLFVIPESPRWLAKVGKWEEFEIALQRLRGESADISYESNEIKDYTRRLTDLSEGSIVDLFQPQYAKSLVVGVGLMVLQQFGGVNGIAFYASSIFESAGVSSKIGMIAMVVVQIPMTTLGVLLMDKSGRRPLLLISATGTCIGCFLVGLSFSLQFVKQLSGDASYLALTGVLVYTGSFSLGMGGIPWVIMSEIFPIDIKGSAGSLVTVVSWVGSWIISFTFNFLMNWNPAGTFYVFATVCGATVIFVAKLVPETKGRTLEEIQYSIGYVEL", "output": "Sugar transporter."}]}
+{"id": "function_test_2854", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPKHEFSVDMTCEGCSNAVTRVLNKLGGVQFDIDLPNKKVCINSEHSVDTLLETLGKTGKAVSYLGPK", "output": "Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity)."}]}
+{"id": "function_test_2855", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSVTHGKMGLSLTQEILSHLGLANKTAAWGTLGTLRTFLSFSADKDVQRLLKAIAGQGVDRIAILDVLTNRSREQRQLISRAFHERTQQDLLKSLQAALSGNLERIVVALLQPAAHLDARELRTALKGSGSAEDVALEILATRTPPQLQECLAVYKHNFQVDAAEDIKSETRGILRDLLLALAKGGREAYTGIIDYNLAAQDVQALKQAEGPSTERTWVLVFTQRNPEHLVRVLNQYQWYTGHGLEKTVRARFHGAACVALLNLASVIRNTPLYFADKLHQALQETEPNYQALMRILISRSETDLLSIRAEFRKKFGKSLYSSLQDAVKGDCRSALLALCRAEDL", "output": "May act as a low affinity receptor for acetylcholine."}]}
+{"id": "function_test_2856", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MMLSKIINNISKSGLRNTTNSKNGGLLYFQNYYMKSSTTITRLNSGNNNYSNNNNNNNNIILNDKFLNKQQNDKKIIYNNIFEEKNQFLKRIYSTSTTTTSTTTTTNINENNIKNENNNENNNENSNNNNEQSIKSNQTKSKGFLRGPYMTLIKLPITVYVTLTAIAGYVAACPIGAFDWVVLSQVSIGTFLASCSANIHNQEIEVQHDRKMPRTKDRPLVIGTINRGKAWVGSIALLTLGFGTMAVTPSLFVPGTLAACNVILYCWYTDLKRVTPLNTWIGAFVGAIPPLIGSVAATGEFEAIGMLLATFMYIWQIPHFLALSQVLREQYRGAGYKMLSVTHEKKTVDRVSLAHALFGIPLPFIFDYFFNFNVHPITLTCMALSSASLALPFITKISPKRLYIISLISLPITLFLSCLLRQPFAYYTDDDDEDKDKDNQNQIENQDKK", "output": "Converts protoheme IX and farnesyl diphosphate to heme O."}]}
+{"id": "function_test_2857", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MANNSPALTGNSQPQHQAAAAVVQQQQQCGGGGATKPAVSGKQGNVLPLWGNEKTMNLNPMILTNILSSPYFKVQLYELKTYHEVVDEIYFKVTHVEPWEKGSRKTAGQTGMCGGVRGVGTGGIVSTAFCLLYKLFTLKLTRKQVMGLITHTDSPYIRALGFMYIRYTQPPTDLWDWFESFLDDEEDLDVKAGGGCVMTIGEMLRSFLTKLEWFSTLFPRIPVPVQKNIDQQIKTRPRKIKKDGKEGVEEIDRHIERRRSRSPRRSLSPRRSPRRSRSRSHHRDGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSLDRGLDRRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKDRGNDRERDRERSRERSKEQRSRGEGEEKKHKEDKEDRRHRDDKKESKKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKDKASKHKNESKEKSNKRSRSGSQGRTGSVEKRKREHSPSREKSRKRSRSQDRSHKRDHDSKDQSDRQDHQRSQSVEPESQEKEHKNKDETV", "output": "May be required for pre-mRNA splicing."}]}
+{"id": "function_test_2858", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSKPPPKPVKPGQVKVFRALYTFEPRTPDELYFEEGDIIYITDMSDTNWWKGTCKGRTGLIPSNYVAEQAESIDNPLHEAAKRGNLSWLRECLDNRVGVNGLDKAGSTALYWACHGGHRDIVEMLFTQPNIELNQQNKLGDTALHAAAWKGYADIVQLLLEKGARTDLRNNEKKLALDMATNAACASLLKKKQGTDAVRSLSNAEDYLDDEDSD", "output": "Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity."}]}
+{"id": "function_test_2859", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLIYKDIFTDDELSSDSFPMKLVDDLVYEFKGKHVVRKEGEIVLAGSNPSAEEGAEDDGSDEHVERGIDIVLNHKLVEMNCYEDASMFKAYIKKFMKNVIDHMEKNNRDKADVDAFKKKIQGWVVSLLAKDRFKNLAFFIGERAAEGAENGQVAIIEYRDVDGTEVPTLMLVKEAIIEEKC", "output": "Involved in calcium binding and microtubule stabilization."}]}
+{"id": "function_test_2860", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGKTDGSSWFTAVKNVFRSPEKLIPRRINRRQDNDLVEEVEDELHQRPKRRKRRWLFKKVSSDPCAINVGINTTSTAINAIAAEETEKTVSPAAKETVFFCRTSVYLKRHVAAILIQTAFRGCLARTAVRALKGVVKLQALVRGHNVRRRTSITLQRVQALVRIQALALDHRKKLTTKLGDEISYSHAFSKQMWRTMEREAHSESELEDKRPSRLNGYGYQETGRRMSTDQAIVEPVKIVEIDKYNNTYSHHQQLNDQTPRGNSFVTRQAHSIPNYMSTTASTVARFRRPQSVPKQRSNRTCLDNNEPRLRLVRKRLSFHNDNPQSYGYIAGDGYFWYDIDKRTNAHEDFQY", "output": "May be involved in cooperative interactions with calmodulins or calmodulin-like proteins (By similarity). Recruits calmodulin proteins to microtubules, thus being a potential scaffold in cellular signaling and trafficking (By similarity). May associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level (By similarity)."}]}
+{"id": "function_test_2861", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSTSSCSFKDRRVSILCCKFCKQVLSSRGMKAVLLADTEIDLFSTDIPPTNAVDFIGRCYFTEICKCKLKDIACLKCGNIVGYHVIVPCCSCLLSCNNGHFWMFHSQAVYGINRLDSTGVNFLLWGNLPEVEENTDEDMLDISAEECIR", "output": "May play a role in the regulation of cellular reactive oxygen species metabolism. May participate in cell growth regulation (By similarity)."}]}
+{"id": "function_test_2862", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSQTENAVTSSSGNKRAYRKGNPVPARERQRASLARRSNTHKAFHAVIQARLKDRLSELADEEGITQAQMLEKLIESELKRRATL", "output": "This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein RepA."}]}
+{"id": "function_test_2863", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDAHDGEADELPPPPPVPANVVPIKADDVESEVPANKPAKPKRFPMARPGLGRKGQPIQLLANHYKVSVKSSEEYFFHYNVILKYEDDRPVDGKGVGRKVIDKLQQTYRSELSSKDFAYDGEKSLFTIGALPQVTNEFTVVLEDVSTGKTAANGSPGGNDSPGGSDRKRVRRPYQTKTFKVELCFAAKIPMNAIAQAIKGQESENSQEALRVLDIILRQHSAKQGCLLVRQSFFHNNPNNFVDLGGGVMGCRGFHSSFRGTQSGLSLNIDVSTTMIVKPGPVIDFLLANQKVDHPDRIDWQKAKRALKNLRIRTTPVNSEFKIIGLSDRNCNEQMFSLRQRNGNNGDVDEVEVTVYDYFVKNKGIELRYSGNLPCINVGKPKRPTYFPIELCSLIPLQRYTKALSTLQRSSLVEKSRQKPQERMSVLNDALRHSNYDSDPMLRASGISIAQNFTQVEGRVLQPPKLKAGNGEDIFPRNGRWNFNNKKLIQTCSVDKWAVVNFSARCDVRNLIRDLIRNASAKGIQMAEPFDVFEESPSLRRAPVSRRVDDMFEQIKSKLPGAPKFLLCLLPERKNCEVYGPWKRKCLAEFGIVTQCLAPQRVNDQYLLNLLLKINAKLGGINSLLQIEASPSIPLVSKTPTIILGMDVSHGQPGQSDRPSIAAVVSSRQWPLISKYRASVHTQSPKLEMMSSLFKPRGTEDDGLIRESLIDFYTSSGKRKPDHVIVFRDGVSESQFTQVINIELDQIIEACKFLDEKWSPKFTVIVAQKNHHTKFFQSGSPDNVPPGTVVDKQVCHPRNYDFYMCAHAGMIGTTRPTHYHVLHDEIGFSPDDLQELVHSLSYVYQRSTTAISVVAPICYAHLAAAQVGTFLKFEDMSDASSSQGGHTSVGSVPVPELPRLHEKVRSSMFFC", "output": "Probably involved in the RNA silencing pathway. May bind to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them (By similarity)."}]}
+{"id": "function_test_2864", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGDSQYSFSLTTFSPSGKLVQIEHALTAVGSGQTSLGIKAANGVVIATEKKLPSILVDETSVQKIQSLTPNIGVVYSGMGPDFRVLVRKSRKQAQQYYRLYKETIPVTQLVRETAAVMQEFTQSGGVRPFGVSLLIAGYDDNGPQLYQVDPSGSYFSWKASAMGKNVSNAKTFLEKRYTEDMELDDAIHTAILTLKEGYEGQISANNIEIGIIRSDREFKVLSPAEIKDFLEEVE", "output": "The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity."}]}
+{"id": "function_test_2865", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MASSSMSSSSSWTSKQNKMFERALAVYDKDTPDRWQNVAKAVGSKSAEEVKRHYDILVEDLMNIEQDLVPLPKYKTVDVGSKSRGIDDFDLRLMKNMRIQ", "output": "Probable transcription factor."}]}
+{"id": "function_test_2866", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDEIVEDSSRVMEIEGQNDDLDRCVVEEVELTVPKTDDPTLPVLTFRMWTLGLGACIILSFINQFFWYRQMPLTISGISAQIAVVPLGHLMAKVLPTRMFLEGSKWEFSMNPGPFNVKEHVLITIFANSGAGTVYATHILSAIKLYYKRSLPFLPAFLLMITTQFLGFGWAGLFRKHLVEPGEMWWPSNLVQVSLFSALHEKEKKKKGGMTRIQFFLIVLVTSFAYYILPGYLFTMITSISWICWLGPKSVLVHQLGSGEQGLGIGAIGIDWATISSYLGSPLASPLFATINVTIGFVVIMYVATPICYWLNIYKAKTYPIFSSGLFMGNGSSYDVLSIIDKKFHLDRDIYAKTGPINMSTFFAVTYGLGFATLSATIVHVLLFNGRDLWKQTRGAFQRNKKMDFHTRIMKKNYREVPMWWFYVILVLNIALIMFISFYYNATVQLPWWGVLLACAIAVFFTPLIGVIAATTNQEPGLNVITEYVIGYLYPERPVANMCFKVYGYISMTQALTFIQDFKLGLYMKIPPRSMFMAQVVGTLVSVVVYTGTAWWLMVDIPHLCDKSLLPPDSEWTCPMDRVFFDASVIWGLVGPRRMFGNLGEYAAINWFFLVGAIAPFFVWLATKAFPAHKWISKIHFPVILGATSMMPPAMAVNFTSWCIVAFVFGHFLYKYKRQWWKKYNYVLSGGLDAGTAFMTILIFLSVGRKGIGLLWWGNADDSTNCSLASCPTAKGVIMHGCPVL", "output": "May be involved in the translocation of tetra- and pentapeptides across the cellular membrane in an energy-dependent manner."}]}
+{"id": "function_test_2867", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAERKKRSSIQTNKPNKKPMKKKPFQLNHLPGLSEDLKTMRKLRFVVNDPYATDYSSSEEEERSQRRKRYVCEIDLPFAQAATQAESESSYCQESNNNGVSKTKISACSKKVLRSKASPVVGRSSTTVSKPVGVRQRKWGKWAAEIRHPITKVRTWLGTYETLEQAADAYATKKLEFDALAAATSAASSVLSNESGSMISASGSSIDLDKKLVDSTLDQQAGESKKASFDFDFADLQIPEMGCFIDDSFIPNACELDFLLTEENNNQMLDDYCGIDDLDIIGLECDGPSELPDYDFSDVEIDLGLIGTTIDKYAFVDHIATTTPTPLNIACP", "output": "Probably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity)."}]}
+{"id": "function_test_2868", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRGLDRWIAEAIRSESLDHNGQIICGGLFLEESLPSSSVSFLSSKDCSVNSCRFSQKSSFLKFRRRNGTREPLFLSVSLSINESNGEEEEGEGYNGQNGFKSEKGSVLIGGGQESKEKRRVKENGAGALNTTKHLWAGAFAAMVSRTCIAPLERMKLEYIVRGEQGNLLELIQRIATNEGIRGFWKGNLVNILRTAPFKSINFYAYDTYRGQLLKLSGNEETTNFERFVAGAAAGVTASLLCLPLDTIRTVMVAPGGEALGGVVGAFRHMIQTEGFFSLYKGLVPSLVSMAPSGAVFYGVYDILKSAYLHTPEGKKRLEHMKQEGEELNAFDQLELGPMRTLLYGAIAGACSEAATYPFEVVRRRLQMQSHAKRLSAVATCVKIIEQGGVPALYAGLIPSLLQVLPSAAISYFVYEFMKVVLKVESSA", "output": "Probable mitochondrial adenylate carrier that catalyzes the transport of ATP, ADP and AMP."}]}
+{"id": "function_test_2869", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVVVSKNNEQQSLILTTELLRTAIFNISYIRGLFPVRYFKDMSVPALDLKMKKLMPMDAESRRLIGWMEKGVYDALHKKHLKKLIFYICETVDGPLIEEYIFSFSYSDSDSQDVRMNINITGINTYGGTLNSTADNSTADMTLNQMSSVDEDFGQNARRSNAFVTYQRFSVYISFHIANYRLCYFFASVQRTILMKLLYYEYVPPDYQPPFFRGCSEEEEAQYVWPKIPLRMEIGNVNSQHHVLTVKVKSVLDPYDPCEDENDNMQDDERSKGPDSLHDDQPCKVFTKPSKLILTENKDADHGEVNEEKLLLITPICEILQDVKQDQVEHQLAKVKDTKGRPASIVQNPILQSHEYDIRRLKARLQRLERHISVPDSPQEGIRKWFAAVSSQLFYKVMEACTRRKPILGDAILSSTVKVQNFNAKICSKLLKKPASIYRKKHFTLNSASLRISGLAGSIFAWAVGFCLFSAQIGHVFVQPKTRSSESKPKVTMEELEEKLTPPSSEPKSAPPSSEPKSAPPSSEPLEKLAVIRRILPEIFAQRCGQRNSSFEAFAQRRTTYDYYNIRLNPREIIFRRLQEESKVALALSSANYFVLSILYRFFRQWSEVSLVRRNSRLTGNPSNEAQSSRSNRIEIPTLLDEPDREGSGGHLAAPEDPVDFLAQFDPLIDLEDAYNTQPQYTEAEVNARLLHEDHVEFDLVPVVSWNTEITAKKTLSTTESVAEVFALCGSGDRPLTCMIPGENERPWNPPRGYVCMYEAYFRQCHLWFPIPSLIISFLNRRHMAFSQLTPAAICNFVAALTFGAEEGYLVNVRCFEEMTTLKAIRSPGYWVVNNRPKHNFLPGPKVSNFKNWEEYYFYVRVDLESYERPFSGRKRMWTEFPDRYRPSPDFPVEFEGVLEAIFRARRRTWKDVTRSRVNRIMGKVRKSFISFAAGLLNMPPPPAPIEEERQPLDGEAAASNPPVSAGPSGVDQVSHEMVNPESQDRMCLEGADVVPAQEIAECDRSQSVQVVEPEVQNITDDRSVVVYAAPPAGEEVNTGLTILDQDKDETVAEPGISRRSREEKGKGGANQSKKRSASEAGLDEAAAPKTFRLSRGETLNSDQFTFKYSGEKFLVRDQEAASHLWRNLMLPGTKDFPNPDDLVLKEGYQKFARSSLETAALANDLIATYDRKLKLKLADREAFDNLKKCADQAKAIYAKDMKEMASLRDAAEIHKAEMSSLNDEVKRLNSREADLQKEFSDLQVALVAVKEHGERECNRLRNDRAAKVARTTKKAQARLDRVKAYLKEQEDLVGPKVDAENQARGAEEIVGILMQRGAKIAASELSGLKELTKRATDEVNALNVIELGDDDLNMSPDQLGFSRQISQVAPVADQHGSNVDLLAEVIRRVSVEETNQTT", "output": "Required for normal meiosis."}]}
+{"id": "function_test_2870", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSHQLTFADSEFSSKRRQTRKEIFLSRMEQILPWQNMVEVIEPFYPKAGNGRRPYPLETMLRIHCMQHWYNLSDGAMEDALYEIASMRLFARLSLDSALPDRTTIMNFRHLLEQHQLARQLFKTINRWLAEAGVMMTQGTLVDATIIEAPSSTKNKEQQRDPEMHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQLGNLLHGEEQFVSADAGYQGAPQREELAEVDVDWLIAERPGKVRTLKQHPRKNKTAINIEYMKASIRARVEHPFRIIKRQFGFVKARYKGLLKNDNQLAMLFTLANLFRADQMIRQWERSH", "output": "Involved in the transposition of the insertion sequence IS5."}]}
+{"id": "function_test_2871", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLRPPPPSSVLTASAAAARPPASVVQPQRQAAHRRRAETLRLRRVFEMFDRDGDGVITPAELSGALCRLGARGEAPPAAAALDAVVAAYIAPGMAGLRFAEFEALHAELAGLGGRQAVAAAEAEEEKEADMREAFGVFDEDGDGYISAAELQAVLSRMGLPEAACMARVRDMIAAADRDSDGRVDYEEFKAMMAAGN", "output": "Potential calcium sensor."}]}
+{"id": "function_test_2872", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVSLLFCGPKLAACGLVLSIWGVIMLALLGIFFTTHSAILIEDVPLTEEDLHSQDTPPQSVYKLYNQVGYNCFIAAVIYVGIGFLSFCQVRLNKRKEYLVH", "output": "Endoribonuclease which preferentially cleaves ApU and ApG phosphodiester bonds."}]}
+{"id": "function_test_2873", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MATVVLGGDTMGPERIFPNQTEELGPHQGPTEGTGDWSSEEPEEEQEETGAGPAGYSYQPLNQDPEQEEVELAPVGDGEDVVADIQDRIQALGLHLPDPPVESEDEDEQGATALNNHSSIPMDPEHVELVKRTMAGISLPAPGVPAWARELSDAQWEDVVQKALQARQAAPAWK", "output": "May play an important role in spermatogenesis and/or testis development."}]}
+{"id": "function_test_2874", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSEVRLPPLRALDDFVLGSARLVAPDPCDPQRWCHRVINNLLYYQTNYLICFGLGLALAGYVRPLHTLLSALVVAVALGMLVCAAENRAAVRRCRRSHPAACLAAVLAVGFLVLWAAGGAGTFLLSIAGPVLLILVHASLRLRNLKNKIENKIESIGLKRTPMGLLLEALGQEQEAGS", "output": "May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptotic role in cerulenin-induced neuroblastoma apoptosis (By similarity)."}]}
+{"id": "function_test_2875", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKFLVLLVALLLWPSSLPAYRRVTVTPDEEQNLNHYVQVLQNLILSVPTKEPGRQKKSKSPNNANFIGPRVSRVKELKYTHDVGPGDNDVLINPVSEETTTFPTRGFTLEIDKKKRTKSTAFWSIKPSNVSVVLHAKEPFIEKDEPEPEPEPEPEPEPVEHRTGAPTQVPSVTEPSQDVTSLSGSTDLGTATEEEDVPQLSGDNEMDYLESHDMYNEDVLKRIADINSQLHHVPLPESYKPEYRADIRASKEHLKRSLALAIAAEHKLEKMYKSQMLPQGRSSGGVYDIITVINMLYNSRYKLSEYLDIKYVPLEMRGKATVVVHTLKRILCVGHGEETHNLLKQLLNNNIRILHILDTHDKDDSS", "output": "Involved in fertilization ability of sperm."}]}
+{"id": "function_test_2876", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLGFGRRRLFSALLQVQKRPCQPSRNMRLVQFQAPHLEEPHLGLESGVGGGVVDLNAFDSTLPKTMVQFLEQGETTLSVARRALATQLPVIPRSQVTFLAPVTRPEKVICVGLNYADHCQEQNVRVPKSPIIFSKFSSSIVGPYDEIILPPESKEVDWEVEMAVVIGKKGKHIKATDVMAHVAGFTVAHDVSARDWQMRNGKQWLLGKTFDTFCPLGPALVTKDTIADPHNLKICCRVNGEVVQSSNTNQMVFKTEYLIAWVSQFVTLYPGDLLLTGTPPGVGMFRKPPVFLKKGDEVQCEIEELGVIINKVV", "output": "May have hydrolase activity."}]}
+{"id": "function_test_2877", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSHIRLTQVLIHNNPSSFNSPFIFDISFECVSPIKEDLEWKVIYVGSADNEKNDQVLDSILLGPVAVGQNQFVFEVDPPDANKIPKDDLLGVTVVFLICAYKGEDFIRVGYYVNNDYFEQELKDNPPETPDLSKIQRNVMDDKPVVTGFPIQWN", "output": "Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly (By similarity)."}]}
+{"id": "function_test_2878", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MCGDCVEKEYPNRGTTCLENGSFLLNFAGCAVCSKRDFMLITNRSLKEEDGEEIVTYDHLCKNCHHVVARHEYTFSIMDEFQEYTMLCLLCGKAEDTISILPDDPRQMTLLF", "output": "Transcriptional activator that mediates FGF signaling during neural development (By similarity). Plays a role in the regulation of cell movement (By similarity). Does not bind DNA by itself (By similarity)."}]}
+{"id": "function_test_2879", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPLLRRPPAAPHRTPIHHDKRLHLFSTHNTRHRATVSSLPVTCLRIRYSSSNPVRHLCGIPSSRCHAAADPAPSKIPGGGSGALEAGVVGWRDLLLQVGEVLSLGFPVWVASACAVALWRPPAFLWVSPMAQIVGISFTMLGMGMTLTLDDLKTALLMPKELASGFLLQYSVMPLSGFLISKLLNLPSYYAAGLILVSCCPGGTASNIVTYLARGNVALSVLMTAASTFAAAFLTPLLTSKLAGQYVAVDPMGLFVSTSQVVLAPVLLGALLNQYCNGLVQLVSPLMPFIAVATVAVLCGNAIAQNASAILSSGLQVVMSVCWLHASGFFFGYVLSRTIGIDISSSRTISIEVGMQNSVLGVVLASKHFGNPLTAVPCAVSSVCHSVYGSLLAGIWRSLPPNDKGQ", "output": "May function as sodium-coupled metabolite transporter across the chloroplast envelope."}]}
+{"id": "function_test_2880", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MMKFMCICLCAISAVSANSYGRSRGGYGGAPVGGYAYQVQPALTVKAIVPSYGGGYGGNHGGYGGAYESVPVPVSSAYSGANVGSQYSGSGYGGAPPVDAQAIALAKLALAAPSAGAPLVWKEAPRYAQPVYPPTSYVNQEYGHSEKVKGGSAAAAASSVAAGKKGYKRPSY", "output": "Chorion membrane (egg shell) protein; plays a role in protecting the egg from the environment."}]}
+{"id": "function_test_2881", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSQKQTPLKLNTFQGISIVANTMLGAGLLTLPRALTTKANTPDGWITLILEGFIFIFFIYLNTLIQKKHQYPSLFEYLKEGLGKWIGSIIGLLICGYFLGVASFETRAMAEMVKFFLLERTPIQVIILTFICCGIYLMVGGLSDVSRLFPFYLTVTIIILLIVFGISFKIFDINNLRPVLGEGLGPIANSLTVVSISFLGMEVMLFLPEHMKKKKYTFRYASLGFLIPIILYILTYIIVVGALTAPEVKTLIWPTISLFQSFELKGIFIERFESFLLVVWIIQFFTTFVIYGYFAANGLKKTFGLSTKTSMVIIGITVFYFSLWPDDANQVMMYSDYLGYIFVSLFLLPFILFFIVALKRRITTK", "output": "Involved in the germinative response to L-alanine. Could be an amino acid transporter. Forms a complex at the inner spore membrane which acts as a receptor for L-alanine, thus is involved in the stimulation of germination in response to alanine. Can stimulate germination in the absence of gerD and gerK gene products (fructose and glucose receptors, respectively), but the response is improved in their presence."}]}
+{"id": "function_test_2882", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSYGGSASQDIVTKLIRKIQNTSVSCTRRDENLDSFNQHLKMSLKVAHNTKTFAKHCLHRQVFKNTYRKRKAVEDQRKNLNTQLRQKFASPSDNLLSPCSRKLNDHKSKLFSAKSQPKTLEFVRGKQNIPRKPNVDI", "output": "Component of the FEAR (CDC14 early anaphase release) network which promotes CDC14 release from the nucleolus during early anaphase and is required for the efficient segregation of telomeric and nucleolar regions. Although BNS1 can partially compensate for a lack of SPO12 function when overexpressed, it does not appear to play any role in controlling meiotic nuclear division."}]}
+{"id": "function_test_2883", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDVARDMEKNTTAMGQLMSSSATTAATATGPASPKRPAGRTKFQETRHPVFRGVRRRGRAGRWVCEVRVPGSRGDRLWVGTFDTAEEAARAHDAAMLALCGASASLNFADSAWLLHVPRAPVASGHDQLPDVQRAASEAVAEFQRRGSTAATATATSGDAASTAPPSSSPVLSPNDDNASSASTPAVAAALDHGDMFGGMRTDLYFASLAQGLLIEPPPPPTTAEGFCDDEGCGGAEMELWS", "output": "Transcriptional activator that binds specifically to the DNA sequence 5'-[AG]CCGAC-3'. Binding to the C-repeat/DRE element mediates high salinity- and dehydration-inducible transcription (By similarity)."}]}
+{"id": "function_test_2884", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAFTLYSLLQAALLCVNAIAVLHEERFLKNIGWGTDQGIGGFGEEPGIKSQLMNLIRSVRTVMRVPLIIVNSIAIVLLLLFG", "output": "Regulator of endoplasmic reticulum secretion that acts as a key determinant of brain size. Required for secretion of extracellular matrix proteins. Required for correct brain development by depositing sufficient extracellular matrix proteins for tissue integrity and the proliferation of neural progenitors (By similarity). Acts as a regulator of the unfolded protein response (UPR) (By similarity)."}]}
+{"id": "function_test_2885", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MERLIKNSIAYSRFRGDWECKSQFERKQESQEGHLSQMIFTPEDMPTFNTQHQRIHTDEKLLECKECGKDFSFVSVLIRHQRIHTGEKPYECKECGKAFGSGANLAYHQRIHTGEKPYECNECGKAFGSGSNLTHHQRIHTGEKPYECKECGKAFSFGSGLIRHQIIHSGEKPYECKVCGKSFSFESALTRHHRIHTGEKPYECKDCGKAFGSGSNLTQHRRVHTGEKPYECKGCGMAFSSGSALTRHQRIHTGEKPYICNECGKAFSFGSALTRHQRIHTGEKPYVCKECGKAFNSGSDLTQHQRIHTGEKPYECKECEKAFRSGSKLIQHQRMHTGEKPYECKECGKAFSSGSDLTQHQRIHTGEKPYECKECGKAFASGSKLIQHQLIHTGEKPYECRECRKSFSSGSALNRHQRIHTGQKPYECKECEKTFGTGSTLTQHQRMHTAEKLYECKACGKALGRGSEIQQHKKNHAGEKLCELETP", "output": "May be involved in transcriptional regulation."}]}
+{"id": "function_test_2886", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKGELIDITMKSGLKCDAYVSRPKDSQKELKPVIFVMDAFGLRDWLYEMADKIAEEGYFVVQPNFYYRIGKNIITNLEKLKSADTKDEVICQIRTQMAKINREETVSDVSEMFDFIDKQEGVRKSKEGVAIVGYCFGGGVAMRSAIAFPDIVKVVASFHAGRLAIPDDENSIHKHLKGVKAECYFGHADNDQSMPLDQIHLFEKSLTEAGIKYTSEIYNNPSCAHGWVMGDTLMYNPIGSDKHYDELFKLLKRAL", "output": "Cysteine hydrolase."}]}
+{"id": "function_test_2887", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MHDIDVAIQINMLFLPPTNELIRVDSNSKQLNQPQQQQQQQQQQINNENENSINNQENKENNNKDNNNNNNKEIKQSSEWGSKFSSLFSNMTKKKKSNFDLEMDAIKDAFLLNKPINNEEGLLIYSLDKSKKYIHSLSELDIGYVYLTEKETPIIRQNEDEVILANKVIIQANTMKRFSIKGILQSDVTTNALEIFTKRKMSQGVLFLEEDGSLCRIFYKIQDLITDTIYCNQDDTVMLQKLPNNEGIRFRFRGSFNREQVQQAMLAFSQPSDPQTWKRTIILREQQHHSSQSFTGDSVASRFLNKLSSKTKEDEESNDLKTKRENTVLKLKNRMKIDWDWKYTSTSVPIDQEPPTFIDNMVNRVREKISGSNNKLSDLLSSAKKQPQQQPQKDVTSSSSSSSNSSSPYLDSVDKLVITTNDSSSSNPLPDFDKLSLSSDDKVNNNNVQIENTTPSVPPPPPVGAPPPPPPPPPPPPPPPPSTLKLNRNRISTPKKPNNSGGGGGGGQLTPLQKKMRQLHWNAIPREKLKETFWDNLSPVKGNDNDQTLVESWFSLSPMAKEKMSKENLNNSNNNNNNNSNNNGEEQSLSDSGNTIVISKIIILDLRRSNNICILLSQFKLSYGAIKEAILCFEDGKLSVEQLIALDAMLPISEEEYQSLSSANYQSIEQLGNAERFLIEMMSIQHLQQRVQTYLFKLEVCSLLDSIEINNNQLSKAIEQLRNSRKFIKVLKVIFHIGSILNRGTYLNSTKGFKLDSLSKLSETKSKDQKHTVVDFIEIYIRENQPELLNFYSELDLLDKIPQSSLENILEESNEIENKFKQVDQEIQYHQQLLTNDNNNTLSSSSSSSYDQSKDTYLKVMSPFYDTFNTRFITIKQSTQQTLKQFQECCIYFGEDPQNITSKDFFSNIVKFSIAFKSSSNNAKKSLNLSTLNSK", "output": "Formins play an important role in the nucleation of actin and the formation of linear actin filaments."}]}
+{"id": "function_test_2888", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGKRKSAAKPPPKKRMDKLDTVFSCPFCNHGSSVECRIDMKNLIGEASCRICQENFSTTVNALTEPIDIYSEWIDECERVNNVEDDDGA", "output": "Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions."}]}
+{"id": "function_test_2889", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDINDDSNDDHLASYDIQLCIQESIEASQAIFHPKRLVQLSDQNRKLVEAIRQGRIFELQEYVQYKYALEEADEKGWFPLHEAVVQPIQQILETVLDASYKTLWEFKTCDGETPLTLAVKAGLVENVKTLLDKGVWPNTKNDKGETPLLIAIKRGSYDMVSALIKYNTSLDQPCVKRWSAMHEAAKQGRKDIITLLLNHRGNVHLRDGFGVTPLGVAAEYGHCDVLEHLIHKGGDVFALADDGASVLFEAAGGGNPDCISLLLKYGGSGNVPNRAGHLPIHRAAYEGHYLALKYLIPVTSKHAIQKSGLTPIHSAAEGQNAQCLELLIENGFDVNALLADHISQSYDDERKTALYFAVSNNDIHCTEVLLAAGADPNLDPLNCLLVAVRANRHEIVRLLLSYGANVNCYFMHVNDTRFPSAIQYALNDEIMLRLLLNNGYQVELCFDCMHGNIFGNSFVWSETEEEGLPGWTSCIIKDNPFCEFITVPWMKHLVGGIVRILIDYMDYVPLCAKLKSVLEVQREWPEIRQIIENPCSLKHLCRLKIRRVMGLQRLCQPASIQMLPLPAAMRRYLLFKEFDLYGQ", "output": "May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins."}]}
+{"id": "function_test_2890", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MMQRCLRLQKPLALRRGLRLAQANSQAVATEAPEAEPLDAFERQYLKERIEISPFQRLFLGAGSSIAALLNPRRHDMIACLGETTGEDALWTILDTMQASEEGQRIMADKPRIHTSTIDFKYLETLPPDTFGAAYVKFLKDNQVTPDSRMAVRFLEDPKLAYLMTRYRECHDLIHTVLDMPTNMLGEVAVKWVEALNTGLPMCYGGAVFGAVRLRPKQRRAYLKHYLPWALENGKRTKPLMPVYWEKRWEQNIHELRSELGITVLNKA", "output": "Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides."}]}
+{"id": "function_test_2891", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEAKTFAFLEIAMFIALGIQTFVAVTDAAGKDDEHFSVDYCGMNCTQQEDGSWTACSGRNGECRCYHESGKRSGLCLSTTYIDFSEYGNLSDSDIAAASPRLSMKESH", "output": "Salivary chemokine-binding protein which binds to host chemokines CXCL1, CXCL2, CXCL3, CXCL5 and CXCL8."}]}
+{"id": "function_test_2892", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAIVKVKPTSPGRRAMVKVVNKNLHQGKPFAALLDSQSSTAGRNNNGRITTRHKGGGHKQHYRIVDFRRTKDGIPAKVERLEYDPNRSANIALVLYADGERRYIIAPKGLTVGQQLMSGSEAPIRAGNTLPIRNIPVGTTIHCIEMLPGKGAQMARSAGTSAMLLAREGVYAQVRLRSGEIRRVHIECRATVGEVGNEEHSLRQIGKAGANRWRGIRPTVRGVAMNPVDHPHGGGEGKTAAGRDPVSPWGTPAKGYRTRSNKRTTTMIVQRRHKR", "output": "One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome."}]}
+{"id": "function_test_2893", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLKPPIGILGGTFDPIHIGHLRPAIEARDALGLAEVRLLPNHIPPHRASPFCSSEQRLAMVALAAAENPGFVVDERELKRDTPSWTIDTLIELRHELPDTPLCFLMGMDSLLGLPSWHRWQELLDYAHLVVSTRPGWQPDYPAEVAELLARHQSQQVADLHRLRHGRIWLADNLPVELSATRLRALLATGADPRYLLPPSVAQYIRQQGLYRPA", "output": "Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)."}]}
+{"id": "function_test_2894", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MARVKRALNAQKKRRTVLKASKGYRGQRSRLYRKAKEQQLHSLTYAYRDRRARKGEFRKLWISRINAAARANDITYNRLIQGLKAAGVEVDRKNLAELAVSDPAAFTALVDVARAALPEDVNAPSGEAA", "output": "Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit."}]}
+{"id": "function_test_2895", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNALLLLAALSSQITFNTTQQGDMYTIIPEVTLTQSCLCRVQILSLREGSSGQSQTKQEKTLSLPANQPIALTKLSLNISPDDRVKIVVTVSDGQSLHLSQQWPPSSEKS", "output": "Plays a role in the extracellular assembly of CsgA into thin aggregative fimbriae (Tafi) fibers. Assembly may also require CsgE. Tafi are thought to be assembled via an extracellular nucleation-precipitation (ENP) pathway, and possibly also via an intracellular non-CsgC-dependent pathway (By similarity)."}]}
+{"id": "function_test_2896", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAALQRFPLSKGWSFKDSEDKSEDAWMPVPVVPSVVQQDLQANNKLKDPYIGFNELETRWVNEKSWTYKTTFQKPAVPAGSAIFLAFDGLDTFATVKLDGNVILESDNMFLAHRLDVTKALEAEGDHSLEIDFDCAFLRAKELRKQDSKHNWASFNGDPSRLSVRKSQYHWGWDWGPVLMTAGIWREVRLEVYTARVADLWTDVQLASDHQNAQITAFAEVESVNSDAHKARFTLSLHGQELGREEVSVSEDGSAKVSFDVKSPSLWWPHGYGDATLYEVSVSLVKDQDEVHQVSKKFGIRTAEVVQQPDKHGKSFFFRVNGVDIFCGGSCWIPADNYLPSVTADRYRKWIELMVHGRQVMIRVWGGGNYEDDSFYDACDELGVLVWQDFMFGCGNYPTWPNLLESIRKESVYNVRRLRHHPSIVVWVGNNEDYQVQESAGLTYDFEDKNPENWLKTDFPARYIYEKILPEVVEEYSPSTFYHPGSPWGDGKTTSDPTVGDMHQWNVWHGTQEKYQIFDTLGGRFNSEFGMEAFPHMSTIDYFVENEADKFPQSHVLDFHNKADGHERRIATYLVENLRTATDLETHVYLTQVVQAETMMFGYRGWRRQWGDERHCGGALLWQLNDCWPTISWAIVDYFLRPKPAFYAVARVLNPIAVGVRREHHDWSVTHAQPPKTSKFELWVASSLQKEVQGTVELRFLSINTGLEVRERIVHENVSIVPNGTTNLIVDGLIDYKVHPEPHVLAVRIWVNGELVARDVDWPQPFKYLDLSNRGLEVKLVSESENEQTLLLSAQKPVKCLVFEEREGVRISDSAIDIVPGDEQRVTIKGMKPGDAPLKYKFLGQ", "output": "Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of beta-mannosidic oligosaccharides of various complexity and length. Prefers mannobiose over mannotriose and has no activity against polymeric mannan. Is also severely restricted by galactosyl substitutions at the +1 subsite (By similarity)."}]}
+{"id": "function_test_2897", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPPAKKGPATSARKGQKTRRREKKNVPHGAAHIKSTFNNTIVTITDPQGNVIAWASSGHVGFKGSRKSTPFAAQLAAENAARKAQDHGVRKVDVFVKGPGSGRETAIRSLQAAGLEVGAISDVTPQPHNGVRPPNRRRV", "output": "Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome."}]}
+{"id": "function_test_2898", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRIGPVELSAVKDWDPAPGVLVSWHPTPASCAKALAAPVSAVPPSYVQARQIRSFSEQAARGLDHSRLLIASVEVFGHCDLRAMTYVINAHLRRHDTYRSWFELRDTDHIVRHSIADPADIEFVPTTHGEMTSADLRQHIVATPDSLHWDCFSFGVIQRADSFTFYASIDHLHADGQFVGVGLMEFQSMYTALIMGEPPIGLSEAGSYVDFCVRQHEYTSALTVDSPEVRAWIDFAEINNGTFPEFPLPLGDPSVRCGGDLLSMMLMDEQQTQRFESACMAANARFIGGMLACIAIAIHELTGADTYFGITPKDIRTPADLMTQGWFTGQIPVTVPVAGLSFNEIARIAQTSFDTGADLAKVPFERVVELSPSLRRPQPLFSLVNFFDAQVGPLSAVTKLFEGLNVGTYSDGRVTYPLSTMVGRFDETAASVLFPDNPVARESVTAYLRAIRSVCMRIANGGTAERVGNVVALSPGRRNNIERMTWRSCRAGDFIDICNLKVANVTVDREA", "output": "Catalyzes the acylation of trehalose-2-sulfate-2'-palmitate (SL659) by adding the (hydroxy)phthioceranoyl group at the 3'-position to yield the diacylated intermediate 2-palmitoyl-3-(C43)-phthioceranyl-alpha, alpha'-D-trehalose-2'-sulfate (SL1278)."}]}
+{"id": "function_test_2899", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSKVAVLLRVLPDDAETKPEELYKKIAAALPEKYQVAQYQAEPIAFGLEALRMVILMPEETEGGTEELETIIQSVQGVSQVDVLNVTRFSG", "output": "Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA."}]}
+{"id": "function_test_2900", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSEIGVAVLGVGLMGADHVARIASRISGARVAVVNDQVTEKAERLAATITGCRAIADPLDAIADRDVDAVVLATPGPTHEKQLLACLEHRKPVLCEKPLTTDVETSLEVVRREAELGVRLIQVGFMRRFDDEYRALKALIDGGELGNPLVLHCVHRNPVVPGHFDSAMTVRDSLVHEVDVTRFLFDEEIVSIQIVKPTPNSLAREGLFDPQIAILRTASGRHVDVELFVTTGVAYEVRTELVAEKGSVIIGLDVGLVRKSAPGTWGGTITPSFKERFGQAYDTEIQRWVDAVRSGGTTGIYTDGPTAWDGYAATAVCEAGVQALQSGQPVAVSMVDRVSIPGA", "output": "Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose)."}]}
+{"id": "function_test_2901", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQISIFAVGRMKVGAEQELVHRYLDRFSKSAGAVGLHFRKMQEVSESRAQTACQRMEEEGKRLFEALPEPSRLIVCDERGKSVSSIAFAEKLAFYRDEGVRDLVIALGGPDGHSEQVRDRADFLLSFGLMTWPHQIARILLTEQLYRTVTIANNHPYHRF", "output": "Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA."}]}
+{"id": "function_test_2902", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRYAGTAHKVGDHIDTDAIIPARFLVTTDAQKLGENCMEGLEHGWVARVKSGDIMVGGRNFGCGSSREHAPIAILGAGMPVVVAHSFARIFYRNGFNMGLLLLEVGDDVDKIADGDDIEVDAASGVITNRTTGATITCAPVPQSMRELLDTGGLVPYVRARLERENG", "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."}]}
+{"id": "function_test_2903", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MYILISNDDGYQAEGILKLAERLGTVARVTVMAPERDRSGASNSLTLEDPIRVHPIEPDRFRVQGTPTDCVHLALTGLLEEDPDMVFSGINAGANLGDDVLYSGTVAAAMEGRYLGLPAVAISLAGTWAPVHYDTAARVAVKLLEQIQDDPLPPDSILNVNVPDLPWDEIQGFHATRLGCRHRAEPVIKQHDPRGRTIYWVGPPGSEQDAGPGTDFYAVRNGFVSVTPIQVDLTRHAGLEQVRGWLDGVTW", "output": "Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates."}]}
+{"id": "function_test_2904", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPRVKRGVTARARHKKVLELAKGFRGRRKNVYRIAKQAVMKAGQYAYRDRRNRKRVFRRLWIARINAASRSHGITYSRFIAGIKKAAIDIDRKMLAELAVNDPAAFGSIVEKVKAQLA", "output": "Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit."}]}
+{"id": "function_test_2905", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLDSLKQKKNFQRIKMRIKTGDLVKVINGKEKGKTGEVLKTIPLENRVVVKGINLRTKHVKPTQEGETGRILTEEASLHASNVMFFSKEKNLTSKIEYFIDKEGVKKRRLKKTGEVID", "output": "One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.; "}]}
+{"id": "function_test_2906", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSYKFPDNLNYADTHEYVLEENGLLKIGVSEFAIDQLGDIVFVELADEGATLEKGETFGTIESVKAVEEVYLPFSGEIVSVNESVIENPELLQSDPIGDGWLVILKPESKASIADLMTSEEYQSKVVPK", "output": "The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein."}]}
+{"id": "function_test_2907", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKKLSILAVLAASPAMAATGPFLSLSNTNFIVTLAFLIFMGILLYAKVPGRVLGMLDKRSVQIRTELEEARALREEARTILASYDRKQKEVQEQAARIVASARDEAQAAAEQAKADLRASIARRLAAAEDQIASAEAGAVRAIREQAVSVAVAAAADLLSRQMTPAAASASIDESIKEVEARFH", "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "}]}
+{"id": "function_test_2908", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSRRGTAEEKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQILYRAMKNIQQKTETNPLSVLRQAIRGVTPDIAVKARRVGGSTHQVPVEIGSAQGKALAIRWLLGASRKRPGRNMAFKLSSELVDAAKGSGDAIRKKEETHRMAEANRAFAHFR", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit."}]}
+{"id": "function_test_2909", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTEKLIFELGSPGRQGVLFPANDVPEIPPHELLPRDLIREQEVPLPEVSEGDAVRHFVRLSRMNFGVDVGFYPLGSCTMKYNPKVAEDAAGLSGFANIHPYQPDEISQGALQLMYETQQDLAEITGMDAFTLQPAAGAQGELTGMLIIKAYLESKGETGRNKVIVPDSAHGTNPATAALCGFKVVEVKSDQRGGVDLAALKQLLGPDVAALMLTNPSTLGLFEDNITEIAALVHQAGGLLYYDGANLNAIMGYARPGDMGFDVVHLNLHKTFGTPHGGGGPGSGPVGVKAELAPFLPKPVIIQREGNYLPDYHRPQSIGRVKAFFANFSVIVKAYTYLRSLGGKGLKEVSEHAVLNANYLMKQLSDHFRVPYQRTCMHEFVVSPPEDMKEQGIKTLDIAKRLLDYGYHPPTVYFPLIVEEALMFEPTETESKETLDEFAHNLIKVLAEARENPDKLRNAPYTTPIRRLDEVMAARKPLVGWFPE", "output": "The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein."}]}
+{"id": "function_test_2910", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSGLVPIVVEQTNRGERAYDIYSRLLKDRIIFIGGPIDDHIANLVIAQFLFLEAEDPEKDIHLYINSPGGVVTAGLAIYDTMQYIKPAVSTICLGQAASMGSFLLAAGAPGKRYALPMARIMIHQPLGGVQGQATDIDIHAKEILRMKDLLNDRLAHHTGQPLEQITRDTERDYFMSAEEAKKYGLIDEVMPYRK", "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins."}]}
+{"id": "function_test_2911", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQYSFTEKKRIRKSFAKRPIVHQVPFLLATQLESFSTFLQADVPATQRKPEGLQAAFTSVFPIVSHNGFARLEFVSYALSSPAFNIKECQQRGLTYCSALRAKVRLVILDKESPNKPVVKEVKEQEVYMGEIPLMTPTGSFVINGTERVIVSQLHRSPGVFFEHDKGKTHSSGKLLFSARIIPYRGSWLDFEFDPKDILYFRVDRRRKMPVTILLKAIGLTPEQILANFFVFDNFTLMDEGAQLEFVPERLRGEVARFDITDRDGKVIVQKDKRINAKHIRDLEAAKTKFISVPEDYLLGRVLAKNVVDGDTGEVIASANDEVTESVLEKLREAGIKDIQTLYTNDLDQGPYISSTLRVDETTDRTAARIAIYRMMRPGEPPTEEAVEALFNRLFYSEEAYDLSKVGRMKFNRRVGRDEIVGPMTLQDDDILATIKILVELRNGKGEVDDIDHLGNRRVRCVGELAENQFRAGLVRVERAVKERLGQAESENLMPHDLINSKPISSAIREFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLALYAHLNEYGFLETPYRKVVDSKVTDQIDYLSAIEEGRYMIAQANAAIDENGQLIDELVSSREAGETMMVTPDRIQYMDVAPSQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPCLRPEKPVVGTGIERTCAVDSGTTVQAFRGGVVDYVDAGRIVIRVNDDEAVAGEVGVDIYNLIKYTRSNQNTNINQRPIVKMGDKVSRGDVLADGASTDLGELALGQNMLIAFMPWNGYNFEDSILISEKVVADDRYTSIHIEELNVVARDTKLGPEEITRDISNLAEVQLGRLDESGIVYIGAEVEAGDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLRVPSGMSGTVIDVQVFTREGIQRDKRAQQIIDDELKRYRLDLNDQLRIVEGDAFQRLARMLVGKVANGGPKKLAKGTKIDQAYLEDLDHYHWFDIRLADDEAAAQLEAIKNSIEEKRHQFDLAFEEKRKKLTQGDELPPGVLKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPIEDMPYMADGRPADVVLNPLGVPSRMNVGQVLEVHLGWAAKGLGWRIGEMLQRQAKIEELRVFLTKIYNESGRQEDLESFTDEEILELAKNLREGVPFATPVFDGATEEEMGKMLDLAFPDDIAQQLDMNPSKNQVRLYDGRTGEQFERRVTLGYMHYLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVTGRTKVYENLVKGDHVIDAGMPESFNVLVKEIRSLGIDIDLDRN", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_2912", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPTITSYFGFLLAALTITSVLFIGLSKIRLI", "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex."}]}
+{"id": "function_test_2913", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTYHLDVVSAEKKMFSGVVQKIQVTGSEGELGIFPGHAPLLTAIKPGMIRIVKQFGEEEFIYLSGGILEVQPSVVIVLADTAIRGLDLDEARALESKRKAEAHINNSHGDVDYAQASAELAKAIAKLRVIELTKKAM", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane."}]}
+{"id": "function_test_2914", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPPKKKLVKTFTLQLPAGQATPAPPVGPALGQHGVNIMEFCKSYNAQTESQRGDIVPAEISVYEDRTFTFVLKTPPAARLLIKAAGVAKGSGVPHMEKVGQVSRAQLREIAEKKMADLNANDLDQAEKIIAGTARSMGLNVVD", "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors."}]}
+{"id": "function_test_2915", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSKIIGSDRVKRGMAEMQKGGVIMDVVNAEQARIAEEAGAVAVMALERVPSDIRAAGGVARMANPKIVEEVMNAVSIPVMAKARIGHITEARVLEAMGVDYIDESEVLTPADEEYHLRKDQFTVPFVCGCRNLGEAARRIGEGAAMLRTKGEPGTGNIVEAVRHMRQVNSEVSRLTVMNDDEIMTFAKDIGAPYEILKQIKDNGRLPVVNFAAGGVATPQDAALMMELGADGVFVGSGIFKSEDPEKFAKAIVQATTHYQDYELIGRLASELGTAMKGLDINQLSLEERMQERGW", "output": "Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively."}]}
+{"id": "function_test_2916", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEVTFFGTSAGLPTKERNTQAIALNLEPYSNSIWLFDVGEGTQHQILHHAIKLGKVTHIFITHMHGDHIFGLPGLLSSRSFQGGEQKPLTLVGPKGIKAYVEMSMNLSESHLNYPITYIEIDDHLTYHHDGFTVEAHLLNHGIPSYGYRVMAPETTGTINVEALKNIGLEPGPKYQEVKSHDTFEHNGQVYQSKDFRGESKQGPVVAIFGDTKPCSNERVISRDADVMVHEATYIDGEKHLANNYHHSHIEDVFALIKEANVKRTLITHLSNRYNTEDINEIYQILIQNEDTPNFNFVKDFDSFKV", "output": "Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA."}]}
+{"id": "function_test_2917", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSLRLQEKYEKEVVPALMDKFGYKNIMQAPKLEKIVINMGVGEAKDNPKVLESAVNDLTIITGQKPVLTRAKKSIANFKLRENMAIGCKVTLRKQYMYEFADKLMNVALPRVRDFSGVSDKSFDGRGNYSLGIKEQLIFPEIEYDKIDKVRGMDIVFVTTANTDEEAKELLRLFGMPFAQK", "output": "This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs."}]}
+{"id": "function_test_2918", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRVSCVYATASRWGGPPVASEVRGDAAISTTPDAAPGLAARRRRILFVAEAVTLAHVVRPFALAQSLDPSRYEVHFACDPRYNQLLGPLPFRHHAIHTIPSERFFGNLTQGRFYAMRTLRKYVEADLRVLDEIAPDLVVGDLRISLSVSARLAGIPYIAIANAYWSPYAQRRFPLPDVIWTRLFGVRLVKLLYRLERPLLFALQCMPLNWVRRRHGLSSLGWNLCRIFTDGDHTLYADVPELMPTYDLPANHEYLGPVLWSPAGKPPTWWDSLPTDRPIVYATLGTSGGRNLLQLVLNALAELPVTVIAATAGRSDLKTVPANAFVADYLPGEAAAARSAVVVCNGGSLTTQQALVAGVPVIGVAGNLDQHLNMEAVERAGAGVLLRTERLKSQRVAGAVMQVISRSEYRQAAARLADAFGRDRVGFPQHVENALRLMPENRPRTWLAS", "output": "Catalyzes the transfer of the first rhamnosyl residue on p-hydroxybenzoic acid or phenolphthiocerol derivatives to form, after O-methylation at position 2 of the sugar unit, mono-O-methyl-glycosyl-p-hydroxybenzoic acid derivative (p-HBAD I) and 2-O-methyl-rhamnosyl-phenolphthiocerol dimycocerosate (also called mycoside B) during p-hydroxybenzoic acid derivatives (p-HBAD) and glycosylated phenolphthiocerol dimycocerosates (PGL) biosynthesis."}]}
+{"id": "function_test_2919", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDSYSIIIKPHVTEKTMNLIDKNNEITFVVKRDANKGQIKRAFEELYEEKVARVTTHITPRGNKVAFIKLVEEEMAEELAVKIGVF", "output": "Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome."}]}
+{"id": "function_test_2920", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAKTIGIDLGTTNSCVAVMEGDKVKVIENAEGTRTTPSIIAYKDGEILVGQSAKRQAVTNPNNTLYAIKRLIGRRFDDKVVQKDIGMVPYKIVKADNGDAWVEVNDKKMAPPQISAEILQKMKKTAEDYLGEKVTDAVVTVPAYFNDSQRQATKDAGKIAGLNVKRIINEPTAAALAYGMDKKKGDSTVAVYDLGGGTFDVSIIEIADVDGEQQFEVLSTNGDTFLGGEDFDLALIDYLVEEFKKEQNFNLKGDPLAMQRLKEAAEKAKIELSSAQSTEVNLPYITADASGPKHLVVTISRSKLEALTEALVKRTIDPCKVALEDAGLKASDIDDVILVGGQTRMPLVQKTVEEFFGQEPRKDVNPDEAVAVGAAIQGAVLSGDKTDVLLLDVTPLTLGIETMGGVMTGIIEKNTMIPTKKSQVFSTAEDNQPAVTIKVFQGERKVAAQNKLLGEFNLTDIPPAPRGMPQIEVTFDINADGIMNISAKDKGTGKEQSIQIKADSGLSDEEIEQMVRDAEANAAEDEKFAALAQVRNEADGRIHAIQKALKDAEDKVTEEEKSSVETAISDLELAAKEDDHDDIKAKLEALDNAFLPISQKIYAAGQGAEGAAPQADATEANAADDDVVDAEFTEVNEDDKK", "output": "Acts as a chaperone."}]}
+{"id": "function_test_2921", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLDRLQIIKQKFDEISDLIIQPDVIADQKRYVALNQEYKGLKSLVEKRDEYVILMANIEEANEIIADGSDADMVEMAKMQLEEAKERLPELEEEIKFLLIPKDAEDAKNVMVEIRAGTGGDEASIFAGDLFRMYTKYCENRGWRTSVVDMNEGTSGGFKEVIFEVTGEDVYGTLKFEAGVHRVQRVPQTETQGRVHTSAATVMVLPEAEEFDVQIDMNDVRVDFFCSSGPGGQSVNTTKSAVRLTHIPTGLVAQCQDQKSQHKNKDKAFGVLRSRLYEQELAKKQADDAVKRTSQVSSGDRSAKIRTYNYSQGRVTDHRIGLDVFDMDGVMNGKIQKFVDELQLVNNMEKLKESEIF", "output": "Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA."}]}
+{"id": "function_test_2922", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSRIGKLPIHVPAGVTVTIKDNVVTVKGPKGELVQEVNPDINVTLEDGVIHLTRPTDDKNHRALHGLYRSLINNMVVGCSEGYKKELELVGVGYRVSNTGQLLDLSLGYTHNIYLQLPKEVKVETKSERNKNPLIILESADKQLLGQICAKIRSFRMPEPYKGKGIKFVGEEIRRKSGKSAGK", "output": "This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center."}]}
+{"id": "function_test_2923", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRILGLDLGSKTIGVAVSDPLGFTAQGLTTVRRTNKEKDIAEIKKFCDEYDAKVIVIGLPKNMNGTIGPSGEIAMAFGKVIEEELNVEVKFWDERLTTVAAHKAMLEADLSRNKRKKIVDKVASTYILQGYLDMISRK", "output": "Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA."}]}
+{"id": "function_test_2924", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN", "output": "One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization."}]}
+{"id": "function_test_2925", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRVKTGTVRRRRHKKILKQAKGFYSGRRKHFRKAKEQLERSLVYAYRDRKQKKREFRKLWITRINAACRLNDISYSRFIHGLSKAGIELDRKILADMAMNEPEAFKAVVEKAKAAL", "output": "Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit."}]}
+{"id": "function_test_2926", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSRRGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLMEVKQTESNIDIDNVLTVFPPENRELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHSEVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGTFIKVKKEKFLDELEKSK", "output": "DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion."}]}
+{"id": "function_test_2927", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSDIINETKSRMQKSIESLSRELANISAGRANSNLLNGVTVDYYGAPTPVQQLASINVPEARLLVISPYDKTSVADIEKAIIAANLGVNPTSDGEVIRIAVPALTEERRKERVKDVKKIGEEAKVSVRNIRRDMNDQLKKDEKNGDITEDELRSGTEDVQKATDNSIKEIDQMIADKEKDIMSV", "output": "Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another."}]}
+{"id": "function_test_2928", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKTFSAKGHEVQRDWFVIDATDKVLGRVASEVALRLRGKHKPEFTPHVDTGDFIVVINAGKLRVTGTKATEKTYYRHSGYPGGIYETNFLKMQQRFPGRALEKAVKGMLPKGPLGYAMIKKLKVYAEATHPHAAQQPKALEL", "output": "This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly."}]}
+{"id": "function_test_2929", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAFRDQPLGELALTIPRASALFRQYDMDYCCGGKQTLARAASRKALDVAVIEAELAKLAEQPLSRDWRAAPLAEIIDHIIVRYHDRHREQLPELILQATKVERVHADKPNVPKGLTKYLTMLHQELSSHMMKEEQILFPMIKQGMGAQAGGPISVMESEHDEAGELLEVIKHITHNVTPPPEACTTWKAMYNGINEMIDDLMEHISLENNVLFPRALGGK", "output": "Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions."}]}
+{"id": "function_test_2930", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSDPKNVIFKESECLEGIFIEGPDFDKDIDLKAVLTDYYEKIGFQATHLGKAVKIWKKIEKLKKEEEMVVFLGYTSNMVSSGLRELISYLVRHKKVDVLVTTAGGIEEDFIKCIKPFVLGDWNLNGAILREKGINRIGNVFVPNDRYIEFETYMTRFFDILSKKQNSENKILSASEFCFELGKFMDENLGNEKEKSIVYHAYKNKIPIFCPAITDGSIGDMLYFYKKNEKDGNLLIDVANDIVKLNDMAIDANKTACIVLGGSLPKHSIINANLFREGTDYAIYITTAIPWDGSLSGAPPEEGVSWGKIQEKADFVEIWADATIVFPMLVYGVFK", "output": "Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue."}]}
+{"id": "function_test_2931", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSNPTSTPRADGFRMPAEWEPHEQTWMVWPERPDNWRNGGKPAQAAFTAVAKAIARFEPVTVCASAAQYENARARLDDTNIRVVEISTDDAWVRDTGPTFVIDDQGDVRGVDWGFNAWGGFEGGLYFPWQRDDQVARKILEIERRARYRTDDFVLEGGSIHVDGEGTLITTEECLLNHNRNPHLSQAEIEGILRDHLAVDSIIWLPNGLYNDETDGHVDNFCCYVRPGEVLLAWTDDQDDPNYLRCQAALRILEESRDAKGRKLVVHKMPIPGPLYATQEECDGVDIVEGSQPRDPSIRLAGSYVNFLIVNGGIVAPSFDDPKDAEARAILQRVFPEHEVVMVPGREILLGGGNIHCITQQQPAPRKA", "output": "Mediates the hydrolysis of agmatine into N-carbamoylputrescine in the arginine decarboxylase (ADC) pathway of putrescine biosynthesis, a basic polyamine."}]}
+{"id": "function_test_2932", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPALSGPQYLGEGLKLIMRPGLRLFVLIPLSINLLVFALLIGFAMQQFSHWVDLLMPSLPDWLGFLQYIVWPLFVLLVLVIVFFTFTMVANIISAPFNGFLSEKVEVVVRGRDDFPPFSWAELLAMIPRTMGREMRKLAYFLPRALVLLVLSFVPGVNLVATPLWILFGIWMMAVQYIDYPADNHKLGWNEMLAWLRSKRWACMGFGGMTYLALLIPLVNLVMMPAAVAGATLFWVREEGEKALVR", "output": "High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway."}]}
+{"id": "function_test_2933", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAIQLVGRKAGMTRIFTEDGVSVPVTVIEVEPNRVTQVKTAETDGYQAVQVTVGSRRSSRVNKAAAGHYAKANVEAGRGLWEFRLAGDEKEINVGDELTVADFESIQMVDVTGQSKGKGFQGAIKRHNFSMQDATHGNSLSHRAPGSIGQCQTPGRVWKGKKMAGHMGAAQVTTQSLEVVRVDTERNLILVKGAVPGAVNGDVILQSAVKAR", "output": "One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit."}]}
+{"id": "function_test_2934", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSDSDAMTDPNAVSYSNAIVVLCTAPDEASAQNLAAQVLGEKLAACVTLLPGATSLYYWEGKLEQEYEVQLLFKSNTDHQQALLTYIKQHHPYQTPELLVLPVRDGDKDYLSWLNASLL", "output": "Involved in resistance toward heavy metals."}]}
+{"id": "function_test_2935", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQVNIFYIQKSDEFKTWSEKYSKLISKYGTLKEINVFNKKIALAQNLNAIEAKKSYEEAFMPYKKGYCIALDERGKDLTSIEFAKLIQDKNELSFFIGGAYGLREEFNQSLDFRLSLSKLTLAHQFVKTLLLEQIYRAFCINNNHPYHK", "output": "Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA."}]}
+{"id": "function_test_2936", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MARVKTGVVRRRRHKKVLKLARGFFSARRKHFRKAKEQVERSLVYSYRDRRNKKRDFRRLWIVRINAACRLNDISYSKFINALKKANIELDRKVLADLAMNDAAAFSAIVAQAKKVM", "output": "Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit."}]}
+{"id": "function_test_2937", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVQGTTSDAGKSVLVAGLCRVLARKGIKVAPFKPQNMALNSAVTKDGGEIGRAQAVQAQACNVEPTVHMNPVLIKPNSDTGAQIILQGKALSNMDAVGFHDYKRVAMGTVLDSFAKLTDEYESVMIEGAGSPAEINLRENDIANMGFAEEADVPVIIIADIDRGGVFAHLYGTLALLSESEQARVKGFVINRFRGDIGLLESGLDWLEEKTGKPVLGVLPFLHGLNLEAEDAITAEQELSSQVKLNVVVPVLTRISNHTDFDVLRLNPDINLRYVGKGEKIDKADLVILPGTKSVRDDLDYLRSQGWDKDIQRHIRLGGKVIGICGGYQMLGKLIDDPNGVEGSPGKSEGLGLLDITTTLTDSKQLTNTHAQLCLNGKTANVKGYEIHVGRSEVQGAQPLRLSSGEAEGAISECGQIMGTYLHGFFDEADVLSLVSEWVNGTQIKQQDFEQLKEKGINRIADAIAQHMNLDFLFK", "output": "Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation."}]}
+{"id": "function_test_2938", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAKEKFERSKPHVNVGTIGHVDHGKTTLTAAITKVMAEKNGGMARKFDEIDSAPEEKARGITINTSHVEYESPNRHYAHVDCPGHADYVKNMITGAAQMDGAILVCSAADGPMPQTREHILLSRQVGVPKIVVFLNKCDMVDDEELLELVEMEVRELLDQYEFPGDDTPVIMGSALRAIEGDEAYVEKIVELVQAMDDYIPAPERDTEKPFILPIEDVFSISGRGTVVTGRIERGVVNVGDEVEVVGIRPTQKTTVTGVEMFRKLLDRGEAGDNVGILVRGLKRDDVERGQVLCKPGSIKPHTKFEAEVYVLSKEEGGRHTPFFKGYRPQFYFRTTDITGAVELPEGVEMVMPGDNVKMTITLINPIAMDEGLRFAIREGGRTVGAGVVAKIIE", "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."}]}
+{"id": "function_test_2939", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAEITVGQLAQQTNKEVDALLKQLKSFGIEKSSEKDTLTPTEMKTLLEKINSAKNTATRKKVTSVKLDGKHKINVSVKRKRRVAKKMEQQESTTLEQPQELETMVQEVSQQVDIVKEQDNIEQIVENKEAVKVQEQRQAEIAKPVIKDSGFKITAMPEIKIEEIVAEDDEGLAASDKQAKKKAAKKVFSEAVNTNTKYKCEEEEKKSKAKKAGGKGFKKANPRQLSQLAGDLESFDEFGAKKGKLKAPKVKKQEFTKPVENTVRTVEIHEGITVSELAQKMAVKGAEIVKVLFNMGVMATINQSLDQDTAILIVEEMGHKYTLHNENALEEAVTIVDRSSYKKISRAPVVTIMGHVDHGKTSLLDYIRQTRVVAGEAGGITQHIGAYSVKTDKGSITFLDTPGHEAFTSMRARGAKSTDIVILVVAADDGVMPQTEEAIQHAKAARVPIVVAVNKIDKPEADSDKVISELAQRNVIPESWGGDVMFVNVSAKTGEGVADLLEAVLLQSEVLELEAFAEGLAEGVVIESRLEKGRGPVATVLVQNGNLKQGDNILCGTEYGRVRAMHNDLGKKIKAAGPATPVEILGLSGVPAAGDEMVVIENEKKAKELAAQRSQKQKEAKIAQEQSLKLSNMFNNMGKEGEQQVLKIILKGDVQGSVEAIRESLLKLSTDEVKVDIIASGIGAITSSDVTLAVASTAVVIGFNVRADSAAKKLAETDGVEFRYYNIIYDLIDDVKKAMSGLLSPEMKEQIIGIAEVREVYRSSKFGSIAGCMVIEGVVKRTNPIRVLRNNVVIYEGTLESLKRFKDDASEVKKGLECGIGVKNYNDVREGDQIEVFEVIEVAKEL", "output": "One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex."}]}
+{"id": "function_test_2940", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSSNIINAITGELITIDITLFISLNEFKKFLINRWQIDFNNLLLLLPFGNKINDRIFIDLIGKKNDQSTIYVFDRRLFSLVNNPDNELSSDYLTNIKNLLKGINHPTNNLNQLVKPVNSPYEEVEINEKFLNYHTITSLITTNLGWLSALEIDMHYFQIQISDTLDYIKNIIESLKICQNYLELYCYDVENLYNSNVKFLNQLANNEILKNWLNYYDNILTKLSDINGNKLSSYLNKNELVSISSKIEELDQRVNSNLKKFKIVIDKNIDLRNNINKEISSLSEKITPSSEKYKLEETMLEKFTELVKNLRNDSKVILEKDENEFDKNYMQNLAKSLEKDKKVTVTNLLTISKALYSQANDISEIKSKLQVDSIKLFGQISFIQIETLNIKKLLLNELNKDLEKYQGFELKLAHVQDIPLVYGLYSIENYRRESWVLQINYKHLDFNKSLKTIVEKEKSTRNKWVDNFGSTAVYFTEDMDTLRDFNYLNNIAKGNQSMIKKLEELFKNISNESHNKNLVFIETYIKEVEDLDLDKDVIELFKRYLAVAQGFVIEQPSTKNIISDKETGELINGYQSRIKKLELLLHSARYSNVESWPTGLLNYSNVKLFRNNVATVNSKLSLQSDYMGNISYGSDQLRIKELENVNKQYKTDFKALTDENKLLKDKVTKFNTDISDIQIERNAYKETLTKLNEELSRLTSIEGDFEKHKGEKEIELKIKIDGLVDSNKTLLNQISDLKIESKELESSNRDLLAQLNQKREEHKVLEDSLKQRENEGLRYKDEYEAKLKELTEKFEADRRALEDEIKAAKEQNMKESMEQQTEQSANQSIDQSIEQSTEQSTEQSTEQSMEQSMEQSMEQSVEQSMEHSMEHSMEQSEKQNMGQNDATIDNQSIETPTSEDMHSLDEQSPESQLLKSNTTELQPIKSQELAEDSKAIELKNIQEMLVSKLYEIFSSNVFILENIGLLLTFDEHDNFQIRRVKGLKKNLNQSVLEETGLLNEIEMPVKSDVFSEVKTLFSNYKETFDSRSYISLLSKINQLYDCKLYETAVIKRFEDIELLAKKLAKENKAKKNLFEKYRCERITLKNFEVGDLALFLPTRENCITEDVSVASWNSSFSSVDLSTPPPFGEPITNQSHSGTAKDKNKHNLEKRPWAAFTAFEETARYFLKDPENIPNNREWFVGKIMHLQRFVVEDHISNPYKLPKGAVWFQVTATVVSHQ", "output": "Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion (By similarity)."}]}
+{"id": "function_test_2941", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQLARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE", "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."}]}
+{"id": "function_test_2942", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVDRVAGEMNLSKTQLRSALRLYTSSWRYLYGVKPGATRVDLDGNPCGELDEQHVEHARKQLEEAKARVQAQRAEQQAKKREAAAAAGEKEDAPPRERKPRPTTPRRKEGAERKPRAQKPVEKAPKTVKAPREEQHTPVSDISALTVGQALKVKAGQNAMDATVLEITKDGVRVQLNSGMSLIVRAEHLVF", "output": "RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism."}]}
+{"id": "function_test_2943", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAKEFGRPQRVAQEMQKEIALILQREIKDPRLGMMTTVSGVEMSRDLAYAKVYVTFLNDKDEDAVKAGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNSLVEGMRMSNLVTSVVKHDEERRVNPDDSKED", "output": "One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA."}]}
+{"id": "function_test_2944", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSDDVALPLQFTEAAAKKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGAVDYTEGLEGSRFVVTNPNAKSTCGCGSSFSI", "output": "Required for insertion of 4Fe-4S clusters for at least IspG."}]}
+{"id": "function_test_2945", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSKEKEVLLNEEIRADEIRCVGDDGKVYGIISSDEALEIANRLGLDLVMIAADAKPPVCKIMDYGKFRYQQEKKQKEAKKKQKVIDIKEIKLSVKIAQNDINYKVKHALEFLEQGKHVRFRVFLKGREMATPEAGVALLEKIWTMIENEANRDKEPNFEGRYVNMLVTPKKA", "output": "IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins."}]}
+{"id": "function_test_2946", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRSAKLKFEKRRSRIRHKISKTSNRVRLSIFKSCRHIYAQIIDDSRSITIASASTLDEKITTLKKSYCNIDNAIKVGEAIAKKADSAGIKEVVFDRGGYKYHGVVKALADAAREKIKF", "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."}]}
+{"id": "function_test_2947", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKKIYFIAGEASGDFAGGRIIRNLKADKELKIIGIGGRNMEEAGNFESLFPISEINLMGFFEVIPHIFRIKKLINKTVEDIIDNKPDILITIDSPGFTYRVAAKVRERLPELKMIHIVAPSVWAYKEGRAAKYAKIYNCLFALLPFEPPYFTKVGLDCRYIGHPIMEQEFYSDKVALRQELEIDEDTKVLCVTLGSRKGEILRHLPIFIPAIEKVYDDHKKKLMVIFPLANPDHERIIKPFLEKVRFNYIFSYERLKSYAVSDLALAKSGTNTLEIAASGTPMIVAYKVNIFSFIIIRLLIKIKYVTLINIIGNREIIPEFIQFNCEANLISDKLKELLLNPQEVDKQITESHKILQELGFKSNIYPSYLATKIIRQEFLK", "output": "Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell."}]}
+{"id": "function_test_2948", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAVSLWQQCIARLQDELSAQQFSMWIRPLQAEMEGDTLVIYAPNRFVLDWVRDKYLNIINQFFTEQMGSDAPSLRFDIGSRPSAKPVVQATAAVRTSRPVTREVTKPSFNTPHAEPMANANHRSNINPTYQFDNFVEGKSNQLGKAAALQVAENPGGAYNPLFLYGGTGLGKTHLLHAVGNGIIKNNPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALFIDDIQFFANKDRSQEEFFHTFNALLEGNHQIILTSDKYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILMRKAQESGINLPDEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQMAMALSKELTNQSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIKEDYANLIRTLSS", "output": "Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids."}]}
+{"id": "function_test_2949", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAAMTVQLDMVSAENHIFSGRVAQLQVSGTEGELGIMPGHAALLTSIKPGMARIVKQNGSEEVFYLSGGILEVQPSSISVLADVVLRADEIDEQAAAEAKLRAETAMAGAGADFNYAAAAVELAQAIAQLRVVETIKKNIAR", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane."}]}
+{"id": "function_test_2950", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTDADFAEQLKDLDTTLRNIESVLDIDRLRADKARLEEAASAPDLWDDQARAQQVTSQLSYVNGEITKLTDLRSRLDDTQVLLELAEAESDPGVLTEVAAEITGLAKSIDEMEVRTLLSGEYDSREALVAIRAGAGGVDAADFAEMLLRMYLRWAERHGYPTEVYETSYAEEAGLKSATFTVKVPYAYGTLSVESGTHRLVRISPFDNQGRRQTSFAGVEVLPVVEQTDHIDIPENEMRTDVYRSSGPGGQSVNTTDSAVRITHIPTGIVVTCQNEKSQLQNKASALRVLQARLLERKRQEEQAKLQGLKTDAAGSWGDQMRSYVLHPYQMVKDLRTEQETGSPSSVFDGELDAFIEAGIRWRKQQQLSGDNV", "output": "Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA."}]}
+{"id": "function_test_2951", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSDHDSGNARRGRASFGAFVRKPVERGAPAGAAAEQGGLDAVQALPDDAVEVGAVVDAYGLKGWVKVATHADAGRGGDALLSARRWWLEKGTQRFSARIVQSKTHGDTVVAQPAGVGDRDAALALRGFRVFVRREDFPALAADEFYWVDLIGLDVVNEQSATLGKVVGMIDNGAHSIMRVEYPSVGKDGRPAAAERLIPFVGVYVKTVDQAARRIVVDWEADY", "output": "An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes."}]}
+{"id": "function_test_2952", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MMTDPIADMLTRIRNAALARHDRTEVPASRIKAAVAEILKSEGFIADVRETEGEGPKKLTIVLKYGRDRQSAIDGVRRVSRPGRRVYVRHDRIPRVFSGLGISILSTSRGLMSDRDARRLKMGGELICEVW", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit."}]}
+{"id": "function_test_2953", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MELQTKSPTTQNDFSQHTPMMRQYLRIKAEYPDLLVFYRMGDFYELFYDDAKKAAKLLNITLTARGQSAGHAIPMAGVPYHAVENYLTKLVRLGESVVICEQIGDPATSKGPVAREVTRIITPGTVSDEALLDEHRDNTLMVIHQEKDRFGIATLDITSGRFLIQEIISENALFAEIERIRPAELLISEENSVHPLKADSIKRRPPWEFDHATALTLLCQQFQTKSLDGFGITHLPLAITAAGCLLQYVNYTQKSALPHIHSIQAEQNEEALFIDANTRRNLELITNLQGEEVHSLAWLLDHTATPMGSRLLRRWINRPLRDQILLQQRQNAVSTLLEKRNYSEIYENLRHIGDLERIVARIALRSARPRDLMQLRQALGVLPTLHQQLTNLPLNKQLQEIKNNLGLFDELFRLLQKAIIENPPIVIRDGGVIADGYDAPLDELRNMSTNSHQFLIDLEQQERERTKINTLKVGYNRIHGYYIEISRAQAKQAPTEYIRRQTLKNVERYITPELKIFEDKVLSSRSRALAREKELYEQLLDTLIEKLIPLQQCASAIANLDVLNTLAERADTLNFNAPQFCDYPIIKIEAGRHPIVENVMTDPFMPNDTHLDEKRRMLIITGPNMGGKSTYMRQTALITLLAYIGSFVPAKNAQLGPIDRIFTRIGAADDLASGRSTFMVEMTETAAILHNATEESLVLMDEVGRGTSTFDGLSLAYACASYLATKLKAFALFATHYFELTALASTLPAVKNVHLDAVEHEEKIIFLHALREGPANKSYGLQVAQLAGIPRSVIQHARQKLEELENPVISETQQPQQNELFLPIENPVLTQLDKLNPDNLTPKQALDILYQLIQLRQQK", "output": "This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity."}]}
+{"id": "function_test_2954", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MASLIQVRDLLALRGRMEATQISHTLHAPQPMIDAMLNQLEIMGKAVRIPEEPDGCLSGSCKSCPEGKACLREWWALR", "output": "May function as a transcriptional regulator that controls feoABC expression."}]}
+{"id": "function_test_2955", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MYIRRLNDQTANQIAAGEVVERPASVVKELIENSIDAHASCIRVDILQGGAKQIRIQDDGDGIHPEDLVLALERHATSKIAKIDDLQDITTLGFRGEALASISAVSRLTLTSRQKNAEMGYRISNISHKIMTPVPAAHPQGTTIDVQDLFYNTPARRKFLRSPATEFQHIRRIIERLALSHFTTEFLLHHNEKEIIHFKSATTISGQENRIKSILGDVFMQSALAIEFSQSGLTLKGYIAEAAYTRSQPDLQYIYVNGRFVRDKLVAQALRQAYHDVLFHGRHPAYVLYLEIDPAFVDINVHPTKHEVRFRDPQWVRDFLIHAVKTALAQAKPGIVHPLPQSTAEYNPITNFAPTPLIEGQGNLSLIQEQPAPYTQTIVHKHPLGHALAQLQGIYILSQNEKGLVIVDMHAAHERILYEKMKKQLAEVGLAMQSLLVPINLSLNPQEITAWQTNKALFARLGFEIESFGPDKIVVRRHPSLLKPKNLENLIRDVLADLITHNTTSRVGERINAALATLACHAALRAPHYLTIEEMEALLREMEKTEHGGLCNHGRPTWKQFDIAELDTFFLRGQ", "output": "This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex."}]}
+{"id": "function_test_2956", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPTLNLFNQAGEKISEVALNDAIFGITPNQQVLYDVVNAQRAALRQGTAKTKTRAEVRGGGKKPWRQKGTGRARQGSIRSPQWRGGGIVFGPIPRSYAVKVNQKVKQLALKSALSYHVLAENLVLVDNITVAEPKTKLFIEIMNNLKLDDRSIVLVDSVDKNLLLASNNLPGAVVREVSQVSVYELLKFKQVVLTQGAVKYYEEVLV", "output": "One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.; "}]}
+{"id": "function_test_2957", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLLGSVPQLDRIAVQLGPFPVYWYGVIIGTGVLLGLWLATREGERLGIHKDTFIDLVLIAVPIAILFARMYYVIFEWEYYSQNPSQIINIRQGGLAIHGGLIGAVITGILFAKRRGLSFWKLADIAAPSILLGQAIGRWGNFMNQEAHGDEVTRQFLEGLHLPDFIINQMYIDGVYYHPTFLYESLWNFAGVILLLALRKVNLRRGELFFTYLIWYSVGRFFVEGLRTDSLMLGPLRIAQVMSIGIVVISIIFIIVRRKMGQADKRYLEN", "output": "Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins."}]}
+{"id": "function_test_2958", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSVYNPNDADFAFTLGIEEEYQIVDPETRELRSYITQILEPGRTILREQIKPEMHQSIVEVGTRPCRTISEARAEIVRLRSAIAGLAARHNLRIVAAGTHPFSSWMQQEITPDERYHMVVGEMQDAALQLLIFGMHCHIGMPNNEVAIELMNVARYICPHLLALSTSSPFWMGRNTGFKSYRSVIFSTFPRTGIPPTFHSASEFERYVQLLVNTGCIDNGKKIWWDLRPHPFFGTLEFRVCDIATKVEECLALAATMQALIVKFYTMFEENTTFRVYRRALINENKWRAQRWGLDGKLIDFGKRKEVEAKALVHEIVELVDDVVDMLGSRREVEYLLKIVENGTSADRQLRVFAETNDLKAVVDNLMVETMEGVPAMAFEADVQSQAAHS", "output": "ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity."}]}
+{"id": "function_test_2959", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKVLLLQDVEHLGKAGEIKDVSGGFGRNYLLPKGFAVLATKSQVKQAEERLAAQRRKAEAARKEAEALAARLAELTLTFTVKVGEQDRLYGSVTNADIAAKLHEVAGIEIDRRKIGLEDPIKRTGEYEVPVELMSGVSSTLKVVVVGE", "output": "Binds to the 23S rRNA."}]}
+{"id": "function_test_2960", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSLPAGVQRRSFGDEDGVLATRGEPAYGEPVVDGWRRWDAHRSKLGATFELGLDTGLSGGDAVLYLGAANGTTVSHVADFAGPTYAVEFAPRPVTDLLAVADSRERLFPLLKDARAPETYAHVVESGVDAIVQDVATRGQADVALSNRQFLADDGRLVAALKARSEDVTADPAAVFEDLLGRLRDGYEVRATARMEPFHEDHLAVVATPR", "output": "Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA."}]}
+{"id": "function_test_2961", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVPRLKSKYEKEIRPTLQKSLGFQSVMRVPKLEKIVINVGMGEAHTNPKAMEACLVEIGQITGQRPVKTFAKKSIAGFKVREGMVLGCKVTLRGHHMYEFLDRFINVALPRVRDFRGVNPKGFDGRGNYNLSVREQIIFPEIQFDKINTIYGINITFVTNTEVDKEAFELFQAFGMPYRTAGK", "output": "This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs."}]}
+{"id": "function_test_2962", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNLENVILSPVVTEKSQDLQTIGERMGKRTVKYTFKVHPDANKTLIKQALKQMYNVVPTNVNVAVYRGKMKRFRNMPSQRPHYKKAVVTFADGANLDFAKV", "output": "One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome."}]}
+{"id": "function_test_2963", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRLILLSGLLLLGIFLANGDEVDPDRKLLNSLIDALMHLQREFANLKGSFLIVHKARSFGSGSERMYVTNKEIKNFEALRQICEQADGHIPSPQLENQNKAFANVLERHGKEAYLVVGDSANFTNWAAGEPNKAAGACVKADTHGSWHSASCDDNLLVVCEFYFIL", "output": "This phospholipase A2 inhibitor binds directly phospholipase A2 in the presence or absence of calcium."}]}
+{"id": "function_test_2964", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPTISQLIRRGRETVAQKSASPALRECPQKRGVCTRVYTTTPKKPNSALRKVARVRLTNGYEVTTYIPGIGHNLQEHSVVLVRGGRVKDLPGVRYHIVRGALDTAGVQNRNRGRSKYGAKRPKK", "output": "With S4 and S5 plays an important role in translational accuracy.; "}]}
+{"id": "function_test_2965", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEMLAFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQADKELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTALRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTEIQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVGPRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGLENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGINAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMRLTEMGREIGLVDDERWTRFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTDAVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMKRMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEGKNRSISKTLQKSK", "output": "NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34."}]}
+{"id": "function_test_2966", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAEPSLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPLKKWWKVRVERVGIPMLTAIPLLTLPQFIMLQYVKGKAESWPGLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRIRNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGMFNFIVMQTLFYLPFFILGALAFIFPHLKALFTTPSRGCTLAAALAFVAYLLNQRYGSGDAWMYETESVITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHITSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR", "output": "Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane."}]}
+{"id": "function_test_2967", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPKKAASPEIKAASFETSLSELEQIVTRLESGELPLEDALNEFERGVQLVRQGQQTLLQAEQRVQILLSDDVDAPLKPFTPDTE", "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."}]}
+{"id": "function_test_2968", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKPGIHPEYAEITATCTCGNVIKVNSTAGKSLHLDVCGACHPFYTGTQKIVDTGGRIDKFNKRFGALGKK", "output": "Binds the 23S rRNA."}]}
+{"id": "function_test_2969", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAKKVVGMIKLQLPAGKASPAPPVGPALGQHGVNIMGFCKEFNAKTANQAGLIIPVVITVYQDRSFSFILKTPPAAVLLKKAAGIESGSGVPNKTKVAKVTKDQIREIAETKMPDLNAGSIETAMSMIAGTARSMGITVEE", "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors."}]}
+{"id": "function_test_2970", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKITAEMIKELRQQTHAGMIACKQALEKTEGNLQKAIVFLREKGIVKASQKQDRTTSEGLINIVFSQNDAFLYELNSETDFVAKNEHFQQLMKTIGEVILQNKLQSVDEVLTFNYQNKTIQDLLLEKTSILGEKITLKRILKVTKKEEEIFGTYKHQGGRISVLVVLENNHPSIAEDIAMHIAAFNPKFLNPDKVNLQFLTTEKNILQKQTEKQLLEEKKPLHILDKIVQNRLNKLLKEICLSEQPFVKNNEQKVKDYLQNNNTNVVSYFRWSIANQ", "output": "Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome."}]}
+{"id": "function_test_2971", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFAIIRTGGKQLRVSEGQEIFVEKLPINPEQNYEFKEVLAVYGEKSILGQPYVEGAKVQAQVIKNDRAKKIIVFKYKRRKKYRCKQGHRQAYTKLLITKIIA", "output": "This protein binds to 23S rRNA in the presence of protein L20."}]}
+{"id": "function_test_2972", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAAISINVSTVKPLGDRIFVKVSPAEEKTAGGILLPDNAQEKPQIGEVVAVGPGKRNDDGSRSELDVKVGDKVLYSKYAGTDVKLSGEDYVLLSEKDILASVA", "output": "Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel."}]}
+{"id": "function_test_2973", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MHGVVVVELKGYREWTESLGPRREHIIQQVQSRIQAAVWRSFTAVGALPHHFRYDFYIALVNGVSLDLVKRAVEKAARASPVGAGFCLGVGETPYEAYLRCGGGGGGAASPAVVAHMDVINSTEATRRNGPLDVYLKVVKLLGQLGERCKDLGCMAFYLGGDNIALFLPSPNAIYSILDGVDLRVRVGVGVAKRPYNAFVRATWALDRLRSAGREGVEVVK", "output": "Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity."}]}
+{"id": "function_test_2974", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLLTDAYEIAKFIKDAKKQTPVKLYVNGDLAGLTIEGATAFGTDQSKIFFADAGLASTFLEEYADRITEVHVEYDRRNSAVPMLDTRHLNARIEPGSWIRDHVVIGDNAVIMMGAIINIGASIGDGTMIDMNAVVGARGTIGKNVHVGAGAVVAGVLEPPSKTPVIIEDGVLIGANAVILEGVRVGKDAVVAAGSVVTEDVPAGSVVAGTPARVIKQKDEKTAEKTQLVDDLRSL", "output": "Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate."}]}
+{"id": "function_test_2975", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MASLREIQMRINSTKSTKQITKAMNMVSASKLNRAQAHSAKFQPYMLKMQEVLGTIANGTTGASHPMLEKRPVKKTGYIVITSDRGLAGAYNANVLREVYREINEKHTTDSYVLFVVGKVGVQFFRSRGITVTDAITGLNDSPSYVDVAEIVKRTVSAFTLGEIDELKLCYNHFMSVISQEVKVETLLPLGEIEASSSTTYEYEPSEEQILAELLPRYAESLIFGALLDAKVAEHASRMTAMQSATDNADDLIGRLTLVYNRARQAAITQEITEIVSGAAAQQ", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex."}]}
+{"id": "function_test_2976", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIQTESTLRVADNTGAREIQCIKVIGAGQKQYANVGDVIVGTIKEATPGGVVKRGQVVRAVIVRTKRGIKRPDGSYIRFDENACVIIDENKDPRGTRIFGPVTRELREKKYMKIISLAPEVL", "output": "Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome."}]}
+{"id": "function_test_2977", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIQQESRLKVADNSGAREILVIKILGGSRVKTGNIGDIIVATVKQATPGGVVKKGDVVKAVVVRTKHGIHRKDGSYIKFDENAAVLINNDKSPKGTRIFGPIARELRGDDFMKIVSLAPEVL", "output": "Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome."}]}
+{"id": "function_test_2978", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSSPLAPVGIFDSGVGGLTVARAIIDQLPDEDIVYVGDTGNGPYGPLTIPEVRAHALAIGDDLVGRGVKALVIACNTASAACLRDARERYDVPVVEVILPAVRRAVATTRNGRIGVIGTRATITSHAYQDAFAAARDTEITAVACPRFVDFVERGVTSGRQVLGLAEGYLEPLQRSGVDTLVLGCTHYPLLSGLIQLVMGDNVTLVSSAEETAKEVLRVLTERDILRPHDAPPATRLFEATGDPEAFMALAARFLGPALTGVQPVRPSGMH", "output": "Provides the (R)-glutamate required for cell wall biosynthesis."}]}
+{"id": "function_test_2979", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEAALLLAKLPEAYQIFDPLVDVLPVIPVFFLLLAFVWQAAVGFR", "output": "One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation."}]}
+{"id": "function_test_2980", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTTATTVKTEYEAIIGLETHCQLSTKTKIFSNSSTAFGADPNTNIDPVCMGLPGVLPVLNEKVLEYAVKTGLALNCQIARYSKFDRKQYFYPDLPKNYQISQYDLPIAEHGWLEIELVDAEGNPSRKRIGITRLHMEEDAGKLVHAGSDRLSGSSYSLVDYNRAGIPLVEIVSEPDLRSGLEAAEYAEELRRIVRYLGVSDGNMQEGSLRCDVNISVRPVGRKEFGTKVEIKNMNSFSAIQRAIDYEIERQIAAIEAGDRIIQETRLWEEGAQRTSSMRVKEGSSDYRYFPEPDLAPIEVSNEQLENWRSELPELPAQKRHHYESELGLSAYDARVLTEDRSIAEYFETAIASGANPKAAANWITQDIAAHLNKQKLTITQIELTPTNLAEIITRIETGKISNAQAKEKLPDLLSGISPEKAFAGLELITDPTVLEPIVDEVIAANPKELEKYRNGNTNLKGFFVGQVLKKTAKRADPKLTNELVEKKLNA", "output": "Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)."}]}
+{"id": "function_test_2981", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MHCAQYTAGRCRSCQWLDKPYPQQLADKQHHLESLLAGHAVTQWLAPVFGRESTFRNKAKMVVSGSVERPLLGMLHRDGTPVDLCACPLYPPSFEPVFTVLKTFIARAGLTPYNVARKRGELKFLLLTESTYNGELMLRFVLRSETKLAQLIAALPWLQQQLPQLAVISANIQPVHMAILEGEREIPLTEQQALPERFNQVPLYIRPQSFFQTNPPVAASLYATARQWVQEHEVHSMWDLFCGVGGFGLHCAGPETQLTGIEISAEAIACARQSAEQLGLKNVSFAALDSTRFATAEAQIPELVLVNPPRRGIGRELCDYLSQMAPKFILYSSCNAETMAKDISLLAGYHIERVQLFDMFPHTSHYEVLTLLALRR", "output": "Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA."}]}
+{"id": "function_test_2982", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSEIPGDLKFLKSHEWARIESNGRVTVGISDHAQGLLGDLVYVELPGVGDTVQVGNGAAVVESVKAASDVYSPVSGTVVEVNSALSDKPETINEDAYGEGWIFVVEIDDKEQLNDLLDPDDYAELLEDDEH", "output": "The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein."}]}
+{"id": "function_test_2983", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSRSIKKGPFIDDHLMKKTLKAKEGKDNRPIKTWSRRSTILPEMIGFTYNVHNGRVFVPVYITENHVGYKLGEFAPTRTFKGHKGSVQKKIGK", "output": "Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA."}]}
+{"id": "function_test_2984", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKQGIHPEYHTDAVVKCACGNSFTTGSVKEELKVEICSKCHPFFTGKQKIVDVGGRVEKFNKRFNLDTK", "output": "Binds the 23S rRNA."}]}
+{"id": "function_test_2985", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKSTVIALREIEEGLITNQILDVRDRQEQHEQEAAELQAVTAIAEGRR", "output": "Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits."}]}
+{"id": "function_test_2986", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPRSLKKGPFIESKLEKRIAALNSKDEKKVVKTWSRSSMIAPEFVGHTIAVHNGKSHIPVYVSENMVGHKLGEFAPTRTYRGHAGGKSEKGGSAPRKK", "output": "Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA."}]}
+{"id": "function_test_2987", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MVEEKTIRLSQVARKLNVATTTIAAYLLEKGFRVENKPNTKITLEQYKILAEEFADSAMDKEEAAELVIGQSYEKEPKVIAKQQEPIKHVHPKEKQVEIEKISLPVIDAPTIIEHKIIEHKTEEPPILQPELPTEEKEELEVIESPQAPQEELKPELETEVQEQDKEIQQELDDTAKVEQAPITKGPEKIDFSKQGEFKGVTVLGKIELAEKKEPKKFQQVASSDIDKKNKKRPRKRVASETGLPSSGKREEEANRYKPKGKVTNKTPEAPKTAVSEKQIQDQIKSTLAKLGGGKNVASRAKYRREKRSLLAEEQAEERLQAAKDAKKLQVTEFIAASDLASLMGVSINQLLSTCMNLGMLVSINQRLDAEAITIIADEFGYQVAFTDVKTQELEEEEEANPEDLVERAPIVTIMGHVDHGKTSLLDYIRNTQITKTEAGGITQHIGAYEVVTESGKHIAFLDTPGHEAFTAMRARGAKLTDIAIIVIAADDGVRPQTKEAINHAKLAGVPIIIAINKMDKPQANPERVKEELAHLNILVEDWGGKYQSQGVSAISGEGVKELLEKILFEAELLELKANSHKKARGTVIEASLDQGRGYLATIMVQDGNLRIGDVVLAGAYYGKIKAMFDYQGKPVKQAGPSTPMQILGLNGAPQAGDLFRAMNTEKEARDIATQRQQILREQGFRTKTHITLDEIGRRLAIGNFKELNIILKGDVDGSVEALSDSLLKLSTEEIKVTILHKGVGAIVESDILLAAASDAIIIGFQVRPTPPVRKLAEKEGIEIRLYSIIYDAINDIKDAMEGMLAPTIEEIITGSASVREIFKITGTGTVAGCYVTEGYIKKNNSIRVIRDGIVIYTGSIKHLKHFKEEMQQVKTGFECGISITNFNDLKVNDVIEGFEQKEVERKL", "output": "One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex."}]}
+{"id": "function_test_2988", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPRSLKKGPFLDLHLLKKVEKAVESGDKKPIKTWSRRSMIIPSMIGLTIAVHNGRQHVPVYVSDEMIGHKLGEFAPTRTYRGHAADKKAKK", "output": "Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA."}]}
+{"id": "function_test_2989", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGKIIGIDLGTTNSCVAIMEGNQVKVIENSEGARTTPSIIAYMDDNEVLVGAPAKRQSVTNPKNTLFAVKRLIGRRFEEKEVQKDIGLMPYSIIKADNGDAWVEAHGEKLAPPQVSAEVLRKMKKTAEDYLGEPVTEAVITVPAYFNDSQRQATKDAGRIAGLEVKRIINEPTAAALAFGLDKAEKGDRKIAVYDLGGGTFDVSIIEIADVDGEMQFEVLSTNGDTFLGGEDFDQRIIDYIIGEFKKEQGVDLSKDVLALQRLKEAAEKAKIELSSGQQTEINLPYITADASGPKHLNLKITRAKLEALVEDLVERTIEPCRIAIKDAGVKVSDIDDVILVGGQTRMPKVMEKVKEFFGKDPRRDVNPDEAVAVGAAIQGQVLSGDRKDVLLLDVTPLSLGIETLGGVMTKMINKNTTIPTKHAQVYSTADDNQGAVTIKVFQGEREMAAGNKLLGEFNLEGIPPAPRGVPQIEVTFDIDANGILHVGAKDKATGKENKITIKANSGLSEAEIDQMIKDAEANAAEDHKLRELADSRNQGDALVHSTKKALTEYGDKLDAGEKEAIEAALKSLEDVLKDTSADKAAIDAKVEELGKVSQKLGEKMYADMQAQQAGAAGAAGAAEGAAHAGGAQQAADDVVDAEFKEVKKD", "output": "Acts as a chaperone."}]}
+{"id": "function_test_2990", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFYWILLALAIATEITGTLSMKWASVGNGNAGFILMLVMITLSYIFLSFAVKKIALGVAYALWEGIGILFITIFSVLLFDEALSTMKIAGLLTLVAGIVLIKSGTRKPGKPVKEATRATI", "output": "Catalyzes the excretion of spermidine."}]}
+{"id": "function_test_2991", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSRTIFCTYLQRDAEGQDFQLYPGELGKRIYNEISKDAWAQWQHKQTMLINEKKLNMMNAEHRKLLEQEMVSFLFEGKDVHIEGYTPEDKK", "output": "Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes."}]}
+{"id": "function_test_2992", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETLPDHEGRHLLPSVVHYQQQGHTVGYAARDNAAQDTANTISSVKRMMGRSLADIQARYPHLPYRFKASVNGLPMIDTAAGLLNPVRVSADILKALAARASESLSGELDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGKEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIADRSDNRVQRELLDAAIAAKIALSDADTVRVNVAGWQGEITREQFNDLISALVKRTLLACRRALKDAGVDPQDVLEVVMVGGSTRVPLVRERVGEFFGRTPLTAIDPDKVVAIGAAIQADILVGNKPDSEMLLLDVIPLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRSLARFALRGIPPLPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLTDGEIASMIKDSMSFAEQDVKARMLAEQKVEAARVLESLTGALTADAALLSAAERQCIDDAAAHLSAVAQGDDVDAIEQAIKNVDKQTQEFAARRMDQSVRRALKGHSVDEV", "output": "Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU."}]}
+{"id": "function_test_2993", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSNTPIELKGSSFTLSVVHLHEAEPEVIRQALEDKIAQAPAFLKHAPVVINVSGLESPVNWPELHKIVTSTGLRIIGVSGCKDASLKVEIDRMGLPLLTEGKEKAVRPAPVEPATPSEPPQNANPITKTRLIDVPVRSGQRIYAPQCDLIVTSHVSAGAELIADGNIHVYGMMRGRALAGASGDREAQIFCTHLTAELVSIAGVYWLSDKIPAEFYGKAARLRLADNALTVQPLN", "output": "Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization."}]}
+{"id": "function_test_2994", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKSYIEPFIASKALSQNSQKAYRYDLQQFCQLVGERVNQDKLLLYQNSIANLSLSAKKRKLSTANQFLYYLYQIKYLNSYFRLTDTMKVMRTEKQQAAIINTDIFYQKTPFVWGQLISLLILELGLTPSEVAGIEVANLDLNFQMLTLKTKKGVRVLPLSQILIPFLEQQLVGKEVYLFEHRGIPFSRQWFFNHLKTFVRSIGYEGLTAQKLREQFILKEKLAGKSIIELSDILGLKSPVTLEKYYKS", "output": "Putative tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site."}]}
+{"id": "function_test_2995", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAKGEGHILAQNKKARHDYHIVETVEAGIVLTGTEIKSVRAARIQLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREITHLANELKGSGMTLVPLKVYLKDGFAKVLIGLAKGKHEYDKRETIKRRDQERDIKKQMKHYNAR", "output": "Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation."}]}
+{"id": "function_test_2996", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKKTQQKEIENVTNITGVRQIELWRRDDLQHPRLDEVAEEVPVALVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSSRRFMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDFQPVGQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSSRASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLSN", "output": "Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH."}]}
+{"id": "function_test_2997", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKSLQALFGGTFDPVHYGHLKPVETLANLIGLTRVTIIPNNVPPHRPQPEANSVQRKHMLELAIADKPLFTLDERELKRNAPSYTAQTLKEWRQEQGPDVPLAFIIGQDSLLTFPTWYEYETILDNAHLIVCRRPGYPLEMAQPQYQQWLEDHLTHNPEDLHLQPAGKIYLAETPWFNISATIIRERLQNGESCEDLLPEPVLTYINQQGLYR", "output": "Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)."}]}
+{"id": "function_test_2998", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVEKMIDKQLMQKRFSERATTYDRFANVQKKMAHALMKRIVHPPQTILEIGCGTGYLTKLLHDAYPKAELTAVDIAPGMIEKAKQRLGDAPITWLCADIEEAELYEMYDLIISNATFQWLTAPKQTIAKLAKQRNERGQLLFSTFGDRTFHELHTSFAYALAIQQIDEPLRIGPSFPTFSEWLAMHDQARGHEQFEVEYFPSVRDFFLSLRHIGATNSTSGRYCQRPSVFKAMMHEYEQRFSEQGLIRATYHCIFIDIT", "output": "Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway."}]}
+{"id": "function_test_2999", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MVNASGDPVIEAAHIWSDTLTVLKHSASLSPREKGWLEGVVPEGVFGSTIVLCVDNNDTLQAIQGDLNDSLLQALRTVTGENMFPAFKVVPKTEPEPLSAAKPAQPYPSEISPTVAEFGKESYGAKPVAAPREPMPATESQFPVGQQKMNRDPETHLNKNFTFDSFVPGDSNRFARTVALAVAEGSGQDFNPLCIYGGSGLGKTHLLNAIGNYALVKDPGLKVRYVTSEEFTNEFIDALQNPNQSQGQIAEFNRRYRQVDVLLIDDIQFLGGKEATLDQFFHTFNALHQANKRIVIASDVAPKNLKGFEARLISRFESGLTVDVKPPDLETRIAILRMIASMNGSKIPSDVLDLIAERFTENIRELEGALTRVTAVASLSNQPVTRALAEQTLQDFFTTDVEIKPTDIISQVAKYFHLTFEDLVGKSRTKNVAVPRQIAMYLAREMTSMSLMDIGQVFGGRDHTTVMHACTRISDRMQQKQEIYNYVMELTVRLKQSNTN", "output": "Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids."}]}
+{"id": "function_test_3000", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNYLFKNGRYMNEEGKIVATDLLVQDGKIAKVAENITADNAEVIEVNGNLIAPGLVDVHVHLREPGGEHKETIETGTLAAAKGGFTTICSMPNTRPVPDCREHMEDLQKRIKEKAHVNVLPYGAITVRQAGSEMTDFETLKELGAFAFTDDGVGVQDASMMLAAMKRAAKLNMAVVAHCEENTLINKGCVHEGKFSEKHGLNGIPSVCESVHIARDILLAEAADCHYHVCHVSTKGSVRVIRDAKRAGIKVTAEVTPHHLVLCEDDIPSVDPNFKMNPPLRGKEDHAALIEGLLDGTIDMIATDHAPHTAEEKAQGIERAPFGITGFETAFPLLYTNLVKKGIITLEQLIQFLTEKPADTFGLEAGRLKEGRTADITIIDLEQEEEIDPTTFLSKGKNTPFAGWKCQGWPVMTIVGGKIAWQKESALV", "output": "Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate."}]}
+{"id": "function_test_3001", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKRMIALDGAQGEGGGQILRSALSLSMITGQPFTITSIRAGRAKPGLLRQHLTAVKAATEICGATVEGAELGSQRLLFRPGTVRGGEYRFAIGSAGSCTLVLQTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKIGIHQQTTLLRHGFYPAGGGVVATEVSPVASFNTLQLGERGNIVQMRGEVLLAGVPRHVAEREIATLAGSFSLHEQNIHNLPRDQGPGNTVSLEVESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLASPAAVGEYLADQLVLPMALAGAGEFKVAHPSCHLLTNIAVVERFLPVRFGLIETDGVTRVSIE", "output": "Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing."}]}
+{"id": "function_test_3002", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVKIINQLSRAGYVTAVRGKNGGIRLGKPASAIRIGDVVRELEPLSLVNCSSEFCHITPACRLKQALSKAVQSFLTELDNYTLADLVEENQPLYKLLLVE", "output": "Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity."}]}
+{"id": "function_test_3003", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLSLLPYTDRHQ", "output": "Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit."}]}
+{"id": "function_test_3004", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSNIPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVDLPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWIFKIKASDESELESLLDATAYEALLEDE", "output": "The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein."}]}
+{"id": "function_test_3005", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIDFGNFYSLIAKNHLSHWLETLPAQIANWQREQQHGLFKQWSNAVEFLPEIKPYHLDLLHSVTAESEEPLSAGQIKRIETLMRNLMPWRKGPFSLYGVNIDTEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGIDPTQLFLCQFEAVRKLLGNDQRAHLLPLGIEQLPALKAFDTVFSMGVLYHRRSPLEHLWQLKDQLVNEGELVLETLVIDGDENTVLVPGDRYAQMRNVYFIPSALALKNWLKKCGFVDIRIADVSVTTTEEQRRTEWMVTESLADFLDPHDPGKTVEGYPAPKRAVLIARKP", "output": "Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs."}]}
+{"id": "function_test_3006", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSAQKPGLHPRNRHHSRYDLATLCQVNPELRQFLTLTPAGEQSVDFANPLAVKALNKALLAHFYAVANWDIPDGFLCPPVPGRADYIHHLADLLAEATGSIPANASILDIGVGANCIYPLIGVHEYGWRFTGSETSSQALSSAQAIISANPGLNRAIRLRRQKESGAIFNGIIHKNEQYDATLCNPPFHDSAAAARAGSERKRRNLGLNKDDVLNFGGQQQELWCEGGEVAFIKKMIEESKGFAKQVMWFTSLVSRGENLPPLYRALTDVGAVKVVKKEMAQGQKQSRFIAWTFMNDEQRRRFVNRQR", "output": "Specifically methylates the adenine in position 1618 of 23S rRNA."}]}
+{"id": "function_test_3007", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLTAIKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKAEEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane."}]}
+{"id": "function_test_3008", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRNDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVALYLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFKKGATEREELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMMGGWLGLITAVVLMILGPTIWVQILGHEKAIFPYEYPALFSISVAFLGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH", "output": "Transports acetate."}]}
+{"id": "function_test_3009", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKYDTSELCDIYQEDVNVVEPLFSNFGGRASFGGQIITVKCFEDNGLLYDLLEQNGRGRVLVVDGGGSVRRALVDAELARLAVQNEWEGLVIYGAVRQVDDLEELDIGIQAMAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDIE", "output": "Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome."}]}
+{"id": "function_test_3010", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSNTDNIFSAPIDKIGDFTFDARVAEVFPDMIQRSVPGYSNIISAIGMLAERFVKPHSNIYDLGCSLGAATLSMRRHIQQEGCTIFAIDNSEAMVERCKLHVNAYRSDTPVEVIEADIREVEIKDASVVVLNFTLQFLSPDDRYALLEKIHAGLRPGGILILSEKYVFEDESSNELLIDLHHDFKRANGYSELEVSQKRSAIENVMRPDSITVHKQRFEKIGFSSSEVWFQCFNFGSMFAIK", "output": "Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)."}]}
+{"id": "function_test_3011", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAKYLGPKLKLSRREGTDLFLKSGLRSIESKCKLEQPPGQHGIRKPRLSDYAIQLREKQKVRRLYGVLERQFKIYYKLAASLKGNTGANLLQLLESRLDNVVYRMGFGCTRSESRQLINHKSIMVNNKVVNIASYQVSPNDQISIRNKSKNQSRIKAALELVEQREKPIWLEVNSTKMEGIFKRFPERSDLSAEINEYLIVELYSK", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; "}]}
+{"id": "function_test_3012", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSLEEKVKNIIVDKLGVEPDEVVEEASFVDDLGADSLDLVELIMSMEETFDLEISDEEAEKILKVKDVIEYIKAHT", "output": "Carrier of the growing fatty acid chain in fatty acid biosynthesis."}]}
+{"id": "function_test_3013", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAPDIATSPEKQKALNLVMTQIERSFGKGSIMRLGDATRMKVETVPTGALPLDLALGGGLPRGRVVEIYGPESSGKTTLALHAIAAVQQTGGIAAFVDAEHALDPAYAAVLGVDIQNLLISQPDTGETALEIVDQLVRSTAVDVVVIDSVAALVPKAEIEGDMGDAHVGLQARLMSQALRKITGNIGKTGCIVIFLNQLRQKIGVTYGNPETTTGGNALKFYASVRLDIRRVQTLKKGTEEFGNRVKVKVAKNKVAPPFRVAEFDIIFGKGISRLGCILDMAEETGVVNRKGAWYSYNGENLAQGRDNTIKYMEENPEFARNIEQLVRQKLEMGAVVSANSVAANETDAEEEYVEEE", "output": "Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage."}]}
+{"id": "function_test_3014", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTDNALRETIIRLAQPVVHTLGLVIWGVETARAGRTIVRLFVDVPTIPQRPGMPEGSEEPSSAITAPAPAHDPQESSGAEAPAAPTSATIEQCEEISRHLALALEVEDSIADAYVLEVSTPGLSRLFFSLEQMIPYVGDVVEARLHTPVASTDPAAHGGPRRVWRGTLVAVEDDAFVLAPVTVSPEGEVEDENQPPVRLPWEAVRRATRMYIFKKPQKPGKKPGKPQGKEVPKGGSGSTAPKKAAAKKKAGRTAAEND", "output": "Required for maturation of 30S ribosomal subunits."}]}
+{"id": "function_test_3015", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPTISQLVRRGRERLQVKKKAPALKESPQKRGVCTRVYTTTPKKPNSALRKVARVRLTNGFEVTSYIPGVGHNLQEHSVVLIRGGRVKDLPGVRYHIIRGTLDAVGVQGRKQGRSKYGAKRAS", "output": "With S4 and S5 plays an important role in translational accuracy.; "}]}
+{"id": "function_test_3016", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNLTHYIASIENYPKEGITFRDISPLMADGKAYSYAIREICQYAADKEIDMIVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPREVVSADYEKEYGLDTLTMHSDAIKPGQRVLIVDDLLATGGTVKATIEMVEKLGGVVAGCAFLIELDGLNGRQALGDIDYKVLMNFPG", "output": "Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis."}]}
+{"id": "function_test_3017", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSRRHKAEKREINPDPKFGDLVVTKFMNAIMLHGKKSVAESIVYGAFDVVEAKSKAEPIAIFHQALENVAPHVEVRSRRVGGATYQVPVDVRPERRQALAIRWLIIAARKRNETTMVDRLSGELLDASNNRGSAVKKREDTHKMADANRAFSHYRW", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."}]}
+{"id": "function_test_3018", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPLINMPDFAGALLDDFAARGAARVDTPVIQPAEPFLDMAGEDLRRRIFLTESETGESLCLRPEFTIPVCLSHIENATGTPKRYAYLGEVFRQRREGGNEFYQAGIEDLGEPATARADARAINDAIGILHKLLPGRPLTVMLGDQAVFEAVVKTLGLPSGWQRRLIQAFGDSTHLDQLLKTLASPQTAHGLDPAVEALLSSGDEAGLIAHLDRTMEDTGYSTNASRSPREIAARLKEKLALAETRLDGAALLLLREFLSLELPLSEATAALAGFADAAGLSLGAALDGFEARIAALADLGVDLSRITYRAAFGRPLDYYTGLVFEVALSGETAVLAGGGRFDRLLTLLGAKHTIPAVGFSLWLDRIELARAR", "output": "Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine."}]}
+{"id": "function_test_3019", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRYRPVIGLEIHVQLSTKTKAFCSCPADVFELPPNTAICPVCTGQPGALPVPNEEMIRFAVKTALALNCKIHKYSRFDRKNYFYPDLPKGYQISQYFYPIATEGFLEIDGDEGRKKVRIRRLHLEEDAGKLVHEGDSITRASYSLVDMNRCGVPLIEIVTEPDISSPREARVFMEKLRSIVRYLGVSTGDMEKGALRCDANISVVDTETGRQSNRVEVKNMNSFRFVEKALEYEFERIVKAMERGEDVERETRGWDMTTKTTVSMRGKEEESDYRYFPEPDIPPVVLSDEYLEEVKKELPELPDEKAKRFMREYDLPEYDAKVLTSSKELAEFFEECVKVVNRPKDLSNWIMTEVLRELNERNIEITESKLTPQHFADLFKLMDEGKISIKIAKEIFPEVFETGKMPSQIVEERGLVQINDEKLIEELVKKAMEQNPKAVEDYKAGKKKAAGFFVGFVMRETKGKANPELTNKIVQKLLEGE", "output": "Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)."}]}
+{"id": "function_test_3020", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSNLKEIKRKIKSVHNTQKTTNAMKLVSTAKLRKAEEAAKKSKVFAQKIDEVLSEIAFKINQYEGLDDKLPFFRKKDNIEKMDIIFVTADKGLCGGFNIKTIKAVNEMLEDCKTKKIKVRLRAIGKTGIEYFNFQNIEILEKYLDTSSSPDYDKACAIIQKAVDDFVNGVTDKIVIIHNGYKNMISQEIRINELLPVEAIVSKEEQKSESLMDLEPEDEEILNDLLKTYFEYNMYFSLVDSLAAEHSARMQAMDNATNNAKARVKQLNLAYNKARQESITTELIEIISGVESMK", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex."}]}
+{"id": "function_test_3021", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPNIASASKRLRQNEVRNLYNRKIKSFLNTQKKKVIKAVDSNDKNLASEEFKKYASALDKAARKSVIHANRAAAKKSDMMKKINAMN", "output": "Binds directly to 16S ribosomal RNA."}]}
+{"id": "function_test_3022", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEKNYMTIPYVIEQTSRGERSYDIYSRLLKDRIIFLGGEINDDVANVVIAQLLFLESADPEKDISLYINSPGGVVTAALGMYDTMQYVKPDVATLCVGQAASAGALLLAGGAKGKRFATANSRIMIHQPSGGSRGMVTDMEIQLKETIRLKSILNNIMANHTGQDIKKLEADMDRDYFMSAEEAKDYGIIDKVFSSRE", "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins."}]}
+{"id": "function_test_3023", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPSLKDLRNRIASVKATQKITKAMQMVAAAKLRRAQEAAEAARPYSQRMGAVLANIAQNVSGEDAPALMVGTGKDDVHLLVVCTAKRGLCGGFNSQIARLARDHARKLLAEGKTVKIITVGKKGADILRREFSALLHDHVDLREVKQLAFVHADQIGHKIIKLFEEGAFDVCTLFYSEFKSVISQVSTAQQLIPASADNEAEMETAGDAIYEYEPDPAAILSTLIPRNISVQIFRALLENVAGEMGAKMSAMDNATRNAGDMINKLSITYNRQRQAQITKELIEIISGAEAL", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex."}]}
+{"id": "function_test_3024", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTEQVQANETETPVAVADERIIRETGIDAKVAGIVEPVINTLGFRLVRVRLSGLNGQTLQIMAERPDGTMTVDDCELVSRTVAPVLDVEDPISGKYHLEISSPGIDRPLVRKSDFSDWAGHIAKVETSIVHEGRKKFRGRIVVGEADSVTIESDQISYGNEPVVRIPFDLISDARLVLTDDLIRDALRKDKALREGRIPGDDLGAEPEDAASTETQEKK", "output": "Required for maturation of 30S ribosomal subunits."}]}
+{"id": "function_test_3025", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MARADKATAVADIAAQFKESTATLITEYRGLTVANLAELRRSLTGSATYAVAKNTLIKRAASEAGIEGLDELFVGPTAIAFVTGEPVDAAKAIKTFAKEHKALVIKGGYMDGHPLTVAEVERIADLESREVLLAKLAGAMKGNLAKAAGLFNAPASQLARLAAALQEKKACPGPDSAE", "output": "Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors."}]}
+{"id": "function_test_3026", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPDDILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLYIFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMYIEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMRTDSLMFFGLRVSQWLSVVFIGLGIMIVIYQNRKKAPYYITEEEN", "output": "Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins."}]}
+{"id": "function_test_3027", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKKAILGKKLGMTQIFNENGKVIPVTVIEAGPCTVIQKKTVEKDGYEAIQVAFGDIREKLRNKPVKGHFAKAGVSVKRHIKEFKLEDLNSLEIGQEIKADVFEAGERVDISGVSKGKGFQGTIRRWNAHRGPMSHGSKFHRAVGSMGASSDPSRTFKNKRMPGHMGNVNTTVLNLEVVRIIPEKNLILIKGGVPGPNKGLVQIRNTVKA", "output": "One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit."}]}
+{"id": "function_test_3028", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSVESFTPTALQFTHGAAHKVKSLVDEEGNDRLKLRVFVTGGGCSGFQYGFTFDEDVADDDTIVEREGVSLVVDPMSFQYLAGAEVDYQEGLEGSRFVIKNPNATTTCGCGSSFSI", "output": "Required for insertion of 4Fe-4S clusters for at least IspG."}]}
+{"id": "function_test_3029", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MARSIWKGPFVDGYLIKKVQKLMESGKSEMIKTWSRRSTILPIFVGFTFSVHNGNKFIPVSVNEEMVGRKLGEFAPTRTFHGHGADKKIKRK", "output": "Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA."}]}
+{"id": "function_test_3030", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGESSNVHEKSQAFYGPNLGYIIELYEQYLEDPSSVDEETRRYFDEFGAPETSTPTEVPVSGPSFDLEKVVSATRLINDIRAFGHKAADIYPLKDHPREQELFELSRYDLTEEDLKQIPARLLSDDAPKPNASALELFRHLLDVYTGTVAIELRHLDDMEEKKWIRRQVEQGALQQTFSKEEKIELFKRLAETELFESFLHKTYVGQKRFSIEGLDAMVPLLDAMVGGLISSGSEHINIGMAHRGRLNVLAHVLGKPYEMIFAEFQHAPNKELIPSEGSIGINFGWSGDVKYHLGLDRKVVEQQKEVRLNLANNPSHLEFVGSVVEGYTRAAQDDRSEKGSAVQHDDLAASILIHGDAAFPGQGIVAETLNMTNLTGYRTGGTVHVIANNTIGFTTDPNDSRSTRYASDIAKGYEIPVFHVNADDPEACVAVAKLISEYRAKFHKDILVDLIGYRRYGHNEMDEPMNTNPVLYKAIKGHQSVRHVYAARLEEEGVMTKDEKAQIEQKIEEALKAARDLVPSEEEDADIVLPDAVHKGFPKVDTSVEREFLTQLNEELLNWPEGFGVFHKLQKVLDRRRDAFSEGGKIDWGHAETLAFASILSDGTPVRLSGQDSERGTFAQRNIMLNDVESGKKFSPLHELSTAKASFSVYNSPLSEGSVLGFEYGYNVFAQDTLVLWEAQYGDFANSAQVMFDQFISAGRAKWGQKSGLVMLLPHGYEGQGPEHSSARMERYLTLAGEKNWTVANLSSAAQYFHILRRQAEMLGKEEIRPMIIMTPKSLLRHPLATSPVEAFTEESFKPIVEQPGLGENTEKVERLVFCTGKMAIDLAEAVGKSEESLDFLHIVRVEEIYPFPVREIRDVISRYPNAREIVWVQEEPKNMGAWTYIEPRLEAVTTNRLDVRYIGRRRRSSPAEGNPTAHKQEQARIIREALSRDVVSSGAGTSTYQKDRK", "output": "E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2)."}]}
+{"id": "function_test_3031", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNEAVSPGALSTLFTDARTHNGWRETPVSDETLREIYALMKWGPTSANCSPARIVFTRTAEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPLLFPHGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQHVDDAFFTGSTLKSNLLINIGYGDSSKLYARLPRLSFEEACGLL", "output": "May reduce toxic product malonic semialdehyde to 3-hydroxypropionic acid, which is excreted."}]}
+{"id": "function_test_3032", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MYKQLDTLLAQAGISLTDQQKQRLLGYVSLLDKWNKAYNLTSVREPRDMLVRHIMDSIVVSPYLQGLRFIDVGTGPGLPGIPLAIVRPDANFTLLDSLGKRVRFLRQVQHELRLDNIEPVQSRVEAFVAEPPFDGVISRAFASLQDMVSWCHHLPAAHHGRFYALKGGVPQDELQSLPAGVSVDQLIRLQVPMLEGERHLVVLKSD", "output": "Specifically methylates the N7 position of guanine in position 527 of 16S rRNA."}]}
+{"id": "function_test_3033", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSVSIKPLEDRIVVRPLEAEQTTASGLVIPDTAKEKPQEGQVVAVGPGRVAENGNRVPVDVAEGDVVLYSKYGGTEVKVGGEEYLVLSARDVLAVVTK", "output": "Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel."}]}
+{"id": "function_test_3034", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNLLQKTRKINAMLQKAAGKPVNFKEMAETLCEVIEANVFVVSRRGKLLGFAIKQSIENERMKRMLEERQFPEEYTKKLFNITETSPNIDINSEYTAFPVENRDLFKTGLTTIVPINGGGERLGTLILSRLDREFNDDDLILAEYGATVVGMEILREKAEEIEEEARSKAVVQMAISSLSYSELEAIEHIFEELEGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGTYIKVLNDKFLTELEKLKSS", "output": "DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion."}]}
+{"id": "function_test_3035", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPNIDNTPLPSSFDAHPEFFQETKWQKVTRRLKEEPLIPIGYAATSYALWRAYKSMKARDSVELNRMFRARIYGHAFTLFAIVAGGIYYGQERKQRKEFEKALQEKQDQEKRDAWLRELEVRDKEDKDWRQRHAAMEMAAKEAEKKMG", "output": "Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes."}]}
+{"id": "function_test_3036", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPRNAHFRFKQFTVRQDQCAMKVCTDACVLGAWADVEDADRILDIGAGTGLLSLMVAQRNTYAMIDAVEIDAEAFYQAGENVEQSPFHDRITLFHSAVQEFVSEHRYDVIITNPPFFQSDLLSPIDKKNIAHHAKSLDFEELLTAIERLLKPEGKFNILFPVDEGSRFAEKAAHAGWKLTRKLTLFHQEDKKAFRLLMRFERAEVAHNVIVEPDLYIYEKDGVTHDPRFRELLKAFYLKF", "output": "Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)."}]}
+{"id": "function_test_3037", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLKAMPASESSGWTLVVPVKTLVAAKTRLSEAAGPHRAALAVAIACDTVEAALSCVIVARIVVVTGDPLAAEALGGVGAHVVGDPEAGLNAALRRGAQEAVRLAPGDAVGALQADLPALRPAELALVLTAAAEFEQAFLPDAADVGTTFYGVRPGVPFTPGFGGESRDRHLRRGAKEICLDGIDSVRRDVDTPDDLRAALALGLGPRTLAMVERIRGGFPSP", "output": "Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor."}]}
+{"id": "function_test_3038", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQDAAPRLTFTLRDEERLMMKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGSGKSDFKGDFFTMDDCRVSPQPSVPMKVICAGQSDAGMAFSARYADFNFCFGKGVNTPTAFAPTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVANVPGAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLPALTQEVA", "output": "Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide. The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN. Requires the flavin reductase RutF to regenerate FMN in vivo."}]}
+{"id": "function_test_3039", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTRRLLLVHAHPDDETITTGGTIARYLSEGAEVTVVTCTLGEEGEVMDPPYAQLVADQADQLGGYRIAELTRALAALSEPAGPVLRPRFLGGAGRWRDSGMAGTPAADHPRAFASADRIAADGPVALLAGIIRELRPQVVVTYDQVGGYGHPDHIAAHTVTTAAVDAAAASGLPGEQWAVAKLYWTVAGRGQIDRGVAAFAETELPGDWSVPESASLPAHDDAALTALIDTRDVAGRKVAALRAHATQLAVAPCGTAFALTNLIAQPVLTEEAYILVRGTAAPGPDGLERDLFAGLE", "output": "Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway."}]}
+{"id": "function_test_3040", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGRGRVQLKRIENKINRQVTFSKRRAGLLKKAQEISVLCDAEVSLIVFSHKGKLFEYTSESCMEKVLERYERYSYAERQLIAPDSHINAQPNWSMEYSRLKAKIELLERNQRHYLGEDLEPMSLKDLQNLEQQLETALKHIRSRKNQLMYESLNHLQRKENEIQEENSMLTKQIKERENILRTQQTQCEQLNRNHDVPPPQPQPFQHPHPYMISHQTSPFLNLGGMYQGEDQTAMRRNNLDLTLEPIYNYLGCYAA", "output": "Probable transcription factor that promotes early floral meristem identity in synergy with APETALA1, FRUITFULL and LEAFY. Is required subsequently for the transition of an inflorescence meristem into a floral meristem. Seems to be partially redundant to the function of APETALA1 (By similarity)."}]}
+{"id": "function_test_3041", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLKPPVDAPIDVKDWIDNRPIAAYQWLILVLCFLIVLFDGFDVAVMGFIAPSLMQDWGLSRAAFGPVMSAGMVGLAIGALTAGPYADRLGRKKVLLIAVSGFSLLSLACAFARNPYELAVLRLLTGIALGAAMPNCTTLLAEYLPTRNRSLMITIMFTGFNMGSGLGGFLSAWLIPHHGWKSVLLAGGLLPLALLPLLWWLLPESARFLAARQAPASQIAAALAKLGGRFAAGTRFTVSEPTTQHKAPARQLFSERYRFGTLALWLTYFMGLLVIYLTMGWLPTLLRDGGLSIERAATITGLFQIGGAVGAIVVGWIMDRRNPNRVIAIAYALGGLCIVSLGALSLESSLLVVGVAAAGFCMSGAQTALNAFAPGYYPTEFRATGVSWMLGIGRFGAIFGSLIGGAVLSLGLGLPLLFTLLGLPAFAAALAILANGHARLRATPAVTAP", "output": "Transporter that specifically mediates the uptake of gallate."}]}
+{"id": "function_test_3042", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKLDTQQISHLLSRQMYHLAPRKKLLIWGGSLGFVLLLLIVASSHQRIRSTILHRTPISTLPVISQEVITADYHPTLLTGFIPTDSDDSDCADFSPSGVIYSTDKLVLHDSLKDIRDSLLKTQYKDLVTLEDEEKMNIDDILKRWYTLSGSSVWIPGMKAHLVVSRVMYLGTNGRSDPLVSFVRVQLFDPDFNELKDIALKFSDKPDGTVIFPYILPVDIPREGSRWLGPEDAKIAVNPETPDDPIVIFNMQNSVNRAMYGFYPFRPENKQVLFSIKDEEPRKKEKNWTPFFVPGSPTTVNFVYDLQKLTILKCSIITGICEKEFVSGDDGQNHGIGIFRGGSNLVPFPTSFTDKDVWVGFPKTHMESCGCSSHIYRPYLMVLVRKGDFYYKAFVSTPLDFGIDVRSWESAESTSCQTAKNVLAVNSISNWDLLDDGLDKDYMTITLSEADVVNSVLRVRGIAKFVDNLTMDDGSTTLSTSNKIDECATTGSKQYCQRYGELH", "output": "Beta-mannosyltransferase involved in cell wall biosynthesis. Responsible for addition of a hexose to the beta-mannose chain (By similarity)."}]}
+{"id": "function_test_3043", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAIMHKIGCAGSEVETDRVLEKDQANNGHFVDSDCCFQETGSTGTANSICTLNDSEDDNSSLNSVDNNECTNLDCGGKKHKNLSPNPSFHVNINAAEFIPKSHNGYAPKSMNPPPEQLDSPCYPHFDQDSSSVIYPSPPSTYYPNMYVSANTFIPMPYAHYTDNMYHAKPVNRPNFLPREGTPPPFAQQPAEQFSPFNSEYESLLDFRALILGNLPVDYKISELLSLIHSGPLEKIQSNPGKRRIIITFLDSADAFFFYERYHPRGFIFHGRPLKLTFARPSPLPESIQNFCSNTAASRNVFIGNLPSSYHEKEIEEAFGKFGKIEHIKILSKKNIAFVHFLNIRDAIKVVRTLSCDPDYHSWRIFFGSDRCANHPPSFDERSCFTSKQNPDTTSDRCRQQESKDNGNRTVFLGNLHTKTKGHEICDLIRHGGLQDFHYIPEKHICFVTFITYSAANAFHDYLAEEEVLLHGRRIKVGWGKESGPLPRVLEDSILMGASRNVYFSHISDSLTTEELELILRQYGEIESIKYLKNRSSGFVAYTNISNAMKAVNGLPIHPLFKKSKIRYAPDRCEQELQKSKSNSPIQQNVPLQQFITPPFSYPVAYCPAIPPGSDPILNFGIQYQPFIPFTAVPSFPFNCNVPNYPQTSDHEND", "output": "Has a role in meiosis."}]}
+{"id": "function_test_3044", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTTIAKQDKIFMKRSGAYHSELDKDIVQKAGNFPLMQFKTKVKVNPKFLLKGDDMDIVDEAITYYKANVFYKNFDMSICEADKLLVYLIFYIQSLLLKFNGRTKVECDKMAYSLAIENFALPGDGKFCLGGIVEPLKASEKEVVRQYMTAIRNETGLRLTQAVFKNDPTKCDKWWMCFNKRKFLNKTI", "output": "Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks."}]}
+{"id": "function_test_3045", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MFKRKSTAELAAQMAKLNGNKGFSSEDKGEWKLKLDNAGNGQAVIRFL", "output": "Binds preferentially to single-stranded DNA and therefore, destabilizes double-stranded DNA. It is involved in DNA replication, repair and recombination. Binds ss-DNA as the replication fork advances and stimulates the replisome processivity and accuracy."}]}
+{"id": "function_test_3046", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIKYFDKNNEVFNLIKDLTGRLNVEILEINIFRNKNNGKIQIVLYSKNFSLDIDFLTDLHKMILLILEANLKYGFTLELSTPGIDRKIKSDREFKIFEGKKIKLMLDNEFEEGFILESKPKSFIFKTDSKEVNVFYSDVKKARLV", "output": "Required for maturation of 30S ribosomal subunits."}]}
+{"id": "function_test_3047", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRNLIISAALVAASLFGMSAQAAEPIESGKQYVELTSAVPVAVPGKIEVIELFWYGCPHCYAFEPTINPWVEKLPSDVNFVRIPAMFGGPWDAHGQLFITLDTMGVEHKVHAAVFEAIQKGGKRLTDKNDMADFVATQGVNKDDFLKTFDSFAVKGKIAQYKELAKKYEVTGVPTMIVNGKYRFDLGSAGGPEKTLQVADQLIDKERAAAKAAK", "output": "Involved in disulfide-bond formation. Acts by transferring its disulfide bond to other proteins (By similarity)."}]}
+{"id": "function_test_3048", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPVSIPNREEILADWEAHPMRRPRIQKVTINIGVGESGERLTKAEIMLQRLTGQKPIRRKAKKTNRDFGIRRGEPIAVKVTLRGPKAYEMLKRLLAAVDYKLKASSFDEHGNVCFGIEEHINIPGVEYDPEIGIFGMDVCVTLERPGFRVARRKRKRARIPTRHKLTKEEGMLYMMEEFGVEIVEEEG", "output": "This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs."}]}
+{"id": "function_test_3049", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MMSRTESRYSSQRTWLLSMVVLAALWSISVQRATARVINDDCPNLIGNRDLYKRVEWICEDCSNIFRNTGMATLCRKNCFFNEDFLWCVYATERTEEMSQLRQWVGILGAGRE", "output": "Inhibits Y-organs where molting hormone (ecdysteroid) is secreted. A molting cycle is initiated when MIH secretion diminishes or stops (By similarity)."}]}
+{"id": "function_test_3050", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKHRDIRKVIIDALESAIGTDAIYFDGRPAVLEEGDFPAVAVYLTDAEYTGEELDADTWQAILHIEVFLEAQVPDSELDDWMETRVYPVLAEVPGLESLITTMVQQGYDYQRDDDMALWSSADLKYSITYDM", "output": "Plays an essential role in tail assembly by capping the rapidly polymerizing tail once it has reached its requisite length and serving as the interaction surface for the completion protein."}]}
+{"id": "function_test_3051", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNWYPWLNAPYRQLVGQHSTGRGHHALLLHSLPGNGEDALIYALSRWLMCQQRQGEKSCGECHSCRLMLAGNHPDWYVLTPEKGKSSIGVELVRQLIDKLYSHAQQGGAKVVWLPHAEVLTDAAANALLKTLEEPPEKTYFLLDCHQPASLLATLRSRCFYWYLACPDTAICLQWLNLQWRKRQIPVEPVAMLAALKLSEGAPLAAERLLQPERWSIRSALCSGLREALNRSDLLSLLPQLNHDDAAERLQWLSSLLLDALKWQQGAGEFAVNQDQLPLVQQLAHIAATPVLLQLAKQLAHCRHQLLSVVGVNRELLLTEQLLSWETALSTGTYSTLPSL", "output": "DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)."}]}
+{"id": "function_test_3052", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSVLKKPDLTDPKLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTLACVIGLSVLAPSPIGEKADPFATPLEILPEWYFFPTFNLLRVIPNKLLGVLSMAAVPVGLITVPFIESVNKFQNPFRRPVAMTVFVFSVVFAIWLGIGATMPINKALTLGLF", "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions."}]}
+{"id": "function_test_3053", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNRDNAIAWSVEDLCVNYDHSDVLCHITFSLPAGAMAAIIGPNGAGKSTLLKASLGLIRASSGQSLFFGQRFSKVHHRIAYMPQRASVDWDFPMTVLDLVLMGCYGYKGIWNRISTDDRQEAMRILERVGLEAFANRQIGKLSGGQQQRAFLARSLMQKADLYLMDELFSAIDMASYQMVVDVLQELKSEGKTIVVIHHDLSNVRKLFDHVILLNKHLVCSGSVEECLTKEAIFQAYGCELELLDYTLKLSRGKYQGSC", "output": "Part of an ATP-driven transport system CT_067/CT_068/CT_069/CT_070 for a metal. Probably responsible for energy coupling to the transport system."}]}
+{"id": "function_test_3054", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MFYNSSKILFTTIMIIGTLITVTSNSWLGAWMGLEINLLSFIPLLSDNNNLMSTEASLKYFLTQALASTVLLFSSILLMLANNLNNEINESFTSMIIMSALLLKSGAAPFHFWFPNMMEGLTWMNALMLMTWQKIAPLMLISYLNIKNLLLISVILSVIIGAIGGLNQTSLRKLMAFSSINHLGWMLSSLMISESIWLIYFIFYSFLSFVLTFMFNIFKLFHLNQLFSWFVNSKILKFSLFMNFLSLGGLPPFLGFLPKWLVIQQLTMCNQYFLLTLMMMSTLITLFFYLRICYSAFMLNYFENNWIMEMNMNSNNTNLYLIMTFFSIFGLFLISLFFFML", "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)."}]}
+{"id": "function_test_3055", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTSTSQLFDPYAEALMAIAREQGLEDRFGEDAALFRSTLAASADLRHLLENPTLFSSQKKAVLNQVFGSSVHPLVLNFLNLLVDRNRIAFLDGIADRYQALLRKLRNVVRADVSSAVPLTEAQVQVITEKVKQLTGAAGVEIESQVDADLLGGVIIKVGSQVLDASLRGQLKRISISLAA", "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "}]}
+{"id": "function_test_3056", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKKNRAFLKWAGGKYPLLDDIKRHLPKGECLVEPFVGAGSVFLNTDFSRYILADINSDLISLYNIVKMRTDEYVQAARELFVPETNCAEVYYQFREEFNKSQDPFRRAVLFLYLNRYGYNGLCRYNLRGEFNVPFGRYKKPYFPEAELYHFAEKAQNAFFYCESYADSMARADDASVVYCDPPYAPLSATANFTAYHTNSFTLEQQAHLAEIAEGLVERHIPVLISNHDTMLTREWYQRAKLHVVKVRRSISSNGGTRKKVDELLALYKPGVVSPAKK", "output": "An alpha subtype methylase, recognizes the double-stranded sequence 5'-GATC-3' and methylates A-2 (By similarity) . May be involved in methyl-directed DNA mismatch repair, initiation of chromosome replication and gene expression (By similarity)."}]}
+{"id": "function_test_3057", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAKVLKKPDLTNPALRAKLKKGMGHNYYGEPAWPNDLLYIFPVVIMGTIALVIGLAVMDPAMVGEPADPFATPLEILPEWYLYPTFQIFRVVPNKLLGVLMNASIPLGLMLIPFIESVNKFQNPFRRPVAMTVFLFGTLVTLWLGIGAAFPLDKSLTLGLF", "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions."}]}
+{"id": "function_test_3058", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "DGVKLCDVPSGTWSGHCGSSSKCSQQCKDREHFAYGGACHYQFPSVKCFCKRQC", "output": "Possesses antifungal activity insensitive to inorganic cations. Causes germ tubes and hyphae to swell and form multiple hyphal buds. Binds to the plasma membrane of the fungus. Has no inhibitory effect on insect gut alpha-amylase."}]}
+{"id": "function_test_3059", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MQAKRTILLLLLLGMVALSSCGLREKHVQGLVNKFVPAGIVKNLLQAGIHKVAKMQYGCPIIKDYCSFHCNDLEKHEGYCHGTKCKCNIPNQYELF", "output": "Inhibits voltage-gated potassium channel."}]}
+{"id": "function_test_3060", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIVVELDDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSENTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMANRGLWDSFVSPKEAKKQLKKDLKSQEQCAGLPTKVSRRTSPALRILEPMWMDSNRTAALRASFLKCPKK", "output": "May play a role in the modulation of host immune response."}]}
+{"id": "function_test_3061", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKEIIAIIRPSKMAQTKTVLEGLGFPAMTANRVLGRGKQKAIVGELGFEVDNKELLNQPGDMRYIPKTMLTLIVPDEDASLVVEAIMKVNKSGQYGDGKIFVCPIEDIITVRTSERGEAAI", "output": "Could be involved in the regulation of nitrogen fixation."}]}
+{"id": "function_test_3062", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPTERSLYTIIRATHKYKDSREQFEMRTHKRLVDIINPTQKTVDALMKLDLPSGVNVEIKL", "output": "Involved in the binding of tRNA to the ribosomes."}]}
+{"id": "function_test_3063", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDSKSGRSESAINIPESNSTKHKSTVVHTATKVAAVAPRGGGWRRGVSIFDFILRICALAAALAATATMGTTDQTLPFFTQFFQFQASYDDLPAFTFFVVANGIASGYLVLSLPFSIATIVRPHAAAIKLLLIIFDTVMVAFTAAAAAAAAAIVYLAHNGNSKTNWFAICQQFNDFCQRVSGAVVASFVAAVILIFLVVLSAVAIRKH", "output": "Regulates membrane-cell wall junctions and localized cell wall deposition. Required for establishment of the Casparian strip membrane domain (CSD) and the subsequent formation of Casparian strips, a cell wall modification of the root endodermis that determines an apoplastic barrier between the intraorganismal apoplasm and the extraorganismal apoplasm and prevents lateral diffusion (By similarity)."}]}
+{"id": "function_test_3064", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEDFVRQCFNPMIVELAEKAMKEYGEDLKIETNKFAAICTHLEVCFMYSDFHFINEQGESIIVEPEDPNALLKHRFEIIEGRDRTMAWTVVNSICNTTGAEKPKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEESRARIKTRLFTIRQEMASRGLWDSFVSPKEAKKQLKKGLKSQGQCAGSLIKAFRRTSPALRILEPMWMDSNRTATLRASFLKCPKK", "output": "May play a role in the modulation of host immune response."}]}
+{"id": "function_test_3065", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSVTVKRIIDNTVIVPKLPANEDPVEYPADYFRKSKEIPLYINTTKSLSDLRGYVYQGLKSGNVSIIHVNSYLYGALKDIRGKLDKDWSSFGINIGKAGDTIGIFDLVSLKGLDGVLPDGVSDASRTRADDKWLPLYLLGLYRVGRTQMPEYRKKLMDGLTNQCKMINEQFEPLVPEGRDIFDVWGNDSNYTKIVAAVDMFFHMFKKHECASFRYGTIVSRFKDCAALATFGHLCKITGMSTEDVTTWILNREVADEMVQMMLPGQEIDKADSYMPYLIDFGLSSKSPYSSVKNPAFHFWGQLTALLLRSTRARNARQPDDIEYTSLTTAGLLYAYAVGSSADLAQQFCVGDSKYTPDDSTGGLTTNAPPQGRDVVEWLGWFEDQNRKPTPDMMQYAKRAVMSLQGLREKTIGKYAKSEFDK", "output": "Encapsidates the genome in a ratio of one N per nine ribonucleotides, protecting it from nucleases. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. Replication is dependent on intracellular concentration of newly synthesized N, termed N(0), which corresponds to the protein not associated with RNA. In contrast, when associated with RNA, it is termed N. During replication, encapsidation by N(0) is coupled to RNA synthesis and all replicative products are resistant to nucleases (By similarity)."}]}
+{"id": "function_test_3066", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "AATAATPATAATPARA", "output": "Antifreeze proteins lower the blood freezing point."}]}
+{"id": "function_test_3067", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPLIPPPNPQKTYQIAVLALGLVLLLAFVLISDHSPKVGDHLHNLPFGGEYKDGTKTIKYFQRPNQHSLSKTLAKSHNTTIFLIILGLIGTLHGLHYFSNNRRISSSLHCVLCQNKH", "output": "Plays a role in viral cell-to-cell propagation, by facilitating genome transport to neighboring plant cells through plasmosdesmata,."}]}
+{"id": "function_test_3068", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "SQSVVATQLIPMNTALTPVMMEGKVTNPIGIPFAEMSQIVGKQVNTPVAKGQTIMPNMVKTYAA", "output": "Contributes to protect fish blood from freezing at subzero sea water temperatures. Lowers the blood freezing point. Binds to nascent ice crystals and prevents further growth (By similarity)."}]}
+{"id": "function_test_3069", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSNTTFRPFTGSSRTVVEGEQAGAQDDMSLLQSLFSDKSREEFAKECKLGMYTNLSSNNRLNYIDLVPKNTGSRALNLFKSEYEKGHIPSSGVLSIPRVLVFLVRTTTVTESGSVTIRLVDLISASSVEILEPVDGTQEATIPISSLPAIVCFSPSYDCPMQMIGNRHRCFGLVTQLDGVISSGSTVVMSHAYWSANFRSKPNNYKQYAPMYKYVEPFDRLKRLSRKQLKNYVRGITNQSVNHGYLLGKPLLKTDEQDPEMIVLEEESLTPTDSNGVGKDKIAVTAKSVAGLPTASLSINRR", "output": "Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding. The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier. Acts by forming a tubular structure at the host plasmodesmata, enlarging it enough to allow free passage of virion capsids (By similarity)."}]}
+{"id": "function_test_3070", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSNQAVANRYAYALFQLAEEKSILSQVVQEMELVKEVVNTTPEFLQLLSHPKVTTEKKRAFIENSFKDSLSETSLHTLLLLVENKRIESLVDMIDSFKEMSYEAQDMAEAVVYSAKPLTSEEQAQIAVIFAKKVNKAKLLVTNVVNKDLLGGLKIRIGDRIYDGSVKSQLDRLERQLIAGTR", "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "}]}
+{"id": "function_test_3071", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MENLTNISIELNQQFNTKEEAIRFCGEKLVEAGCVEPAYIEAMIERDQLLSVYMGNFIAIPHGTEEAKKLVKKSGICVVQVPEGVNFGTEEDEKIATVLFGIAGVGEEHLQLVQQIALYCSDMDNVVQLADALSKEEITENLAIA", "output": "The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II CmtAB PTS system is involved in D-mannitol transport."}]}
+{"id": "function_test_3072", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "SGSCEVKTCWKAMPPFRKVGNVLKEKFDGATEVEQRKIGSTKVLVPKNSQFKPHTDEDLVYLDSSPDFCDHDLKNGVLGTSGRHCNKTSKAIDGCELMCCGRGFHTDEVEVVERCSCKF", "output": "Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Plays an important role in embryonic development (By similarity)."}]}
+{"id": "function_test_3073", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "GFKNVALSTARGF", "output": "The exact physiological function is still unknown. This myotropic peptide is active on the oviduct and, to a lesser extent, on the hindgut. Transferred from the male to the female during copulation."}]}
+{"id": "function_test_3074", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MATSSSLFHPIEKELYSVEHNLKSVAGTRHPILYAAAKHLFEAGGKRLRPAIVLLVAKSTSEQQEIKPGQRRLAEITEIIHTASLVHDDVIDECSTRRGEKTVHKLFNTKIAVLAGDFLFAQSSWYLANIGNLEVVKVITKVITDFAEGEIRQGLVHFDPSISIDDYIEKSFYKTASLVAASCRGAAMLNDLNSQMHNDLYLYGKHMGLAFQIMDDVLDIAGSTKSLGKPSGADFMNGNLTAPILFALTQEGKLDQLIQREFSDERDISLALFLIKKSGGITKAKDLAKEQVQAALCCLQFLPKSAPVSSLKELTHFIITRLS", "output": "Possible role in synthesis of the nonaprenyl side chain of plastoquinone or in synthesis of other prenyl chains such as undekaprenyl pyrophosphate."}]}
+{"id": "function_test_3075", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MERWLQLHVWSKDQQDQDQEHLLDEKIPINRAWMDFLQMSPFLKRKLVTLLETVAKLRTSTVVYPGEERVFSWSWLCEPTQVKVIILGQDPYHGGQATGLAFSVSKTDPVPPSLRNIFLEVSACDSQFAVPLHGCLNNWARQGVLLLNTILTVEKGKPGSHSDLGWIWFTNYIISCLSNQLDHCVFMLWGSKAIEKASLINTNKHLVLKSQHPSPLAARSNRPSLWPKFLGCGHFKQANEYLELHGKCPVDWNLD", "output": "Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or deamination of cytosines. Therefore may reduce deleterious uracil incorporation into the viral genome, particularly in terminally differentiated cells which lack DNA repair enzymes."}]}
+{"id": "function_test_3076", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPLNLRHRHFLRLMDFTPTEIQFLLDLSANLKKAKYTGTEQPRLKGKNIALIFEKTSTRTRCSFEVAAYDQGANVTYIGPSGSQIGHKESMKDTARVLGRMYDGIQYRGYGQELVEILAQYSGVPVWNGLTDDFHPTQILADFLTMLEHGEGKRLNQMKMAYLGDARNNMGNSFVEGAALMGMDLRLVAPKAYWPEQKLLDEVAEMAKKTGAKITCTENVEEGVKGVDFLYTDIWVSMGEPEEAWEQRINLMKPYQVNKALLEKTGNPKVKFMHCLPAFHDENTTVGKEMAQKYGMNGLEVTDEVFESDASIVFDEAENRMHTIKAVMVATLGQ", "output": "Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline."}]}
+{"id": "function_test_3077", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRTLPLNGSRNSSRLPTLLLAAGLAMTPWAPALAAGMEGMDHGSHSMPMGASSDAPAQSRTPIPPVTDADRAAVYTSHSGHQVHDSAINSYFVADKLEWQDANDGSALAWDLSGWIGGDIDRLLLRSEGERTNGKTEEAEVQALWGHAVSSSWDVVAGARQDFKPGAPQTWAAFGLQGQAISDLDVEATAFIGDAGQTAARLEADYDLLLTNDLILQPTGELNFYGKNDPQRGNGSGLSTSEFGLRLRYEITPQFAPYVGVTWNRSYGKTADYAREDDEDVAQARLVVGLRLWF", "output": "Exact function not known. Could be involved in copper resistance (By similarity)."}]}
+{"id": "function_test_3078", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MANYDVLKLDGTKSGSIELSDAVFGIEPNNSVLFEAINLQRASLRQGTHAVKNRSAVSGGGRKPWKQKGTGRARQGTIRAPQWRGGGIVFGPTPRSYAYKMPKKMRRLALRSALSFKAQENGLTVVDAFNFEAPKTKEFKNVLSTLEQPKKVLVVTENEDVNVELSARNIPGVQVTTAQGLNVLDITNADSLVITEAAAKKVEEVLG", "output": "One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.; "}]}
+{"id": "function_test_3079", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPLRVELKPFERIVIGQSVITNSDTRTTFLIDGDAPILREKDILTAETANTPVKRIYLCVQMMYLQNDIPAYQDLYLGFIKELIEAVPSFRETIEATSNHILSGNLYKALRELRPLIKREEELLSR", "output": "Has a post-transcriptional repressor function in flagellum biogenesis. Associates with the 5'-UTR of fljK mRNA and promotes its degradation."}]}
+{"id": "function_test_3080", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTQMTVQVVTPDGIKYDHHAKCISVTTPDGEMGILPNHINLIAPLQVHEMKIRRGGEDEKVDWIAINGGIIEIKDNVVTVVADSAERDRDIDVSRAERAKLRAEREIAQAETTHNIDEVRRAKVALRRALNRINVSKK", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane."}]}
+{"id": "function_test_3081", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTMLISLPTAPSVPNYQSLERPLNFTMAAAAKVRELIQEENNADLALRVYIQGGGCSGFQYGFEFDENRADDDLALETDGVVLLVDPLSLQYLLGAEVDYTESLTGAKFVIRNPNAKTTCGCGSSFSV", "output": "Required for insertion of 4Fe-4S clusters for at least IspG."}]}
+{"id": "function_test_3082", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDIVIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGYIYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVRRDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMISLLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK", "output": "Controls the transcription of the pur operon for purine biosynthetic genes."}]}
+{"id": "function_test_3083", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSFIGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR", "output": "Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA."}]}
+{"id": "function_test_3084", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVYSALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMAEANKAFAHYRW", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."}]}
+{"id": "function_test_3085", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSYAIIEIGGTQIRVEPGRFYEINHLDAAPEDSYVVDKVLLVKDGDNVTIGQPYVAGATVEGEILSHRRGRKVIVYKMQPKKKTRKKRGHRQELTRLLVKSISVNGTAIAEALEVDAKTPVVAG", "output": "This protein binds to 23S rRNA in the presence of protein L20."}]}
+{"id": "function_test_3086", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "SSTCIPSGQPCPYNENCCSQSCTFKENENGNTVKRCD", "output": "Inhibits insect, but not mammalian, voltage-gated calcium channels (Cav)."}]}
+{"id": "function_test_3087", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "ANDPQCLYGNVAAKF", "output": "Has antifungal activity against M.arachidicola with an IC(50) of 125 uM, but not against F.oxysporum. Inhibits human immunodeficiency virus-1 (HIV-1) reverse transcriptase with an IC(50) of 60 uM. Has mitogenic activity towards murine splenocytes. Lacks antiproliferative activity towards HepG2 hepatoma cells. Has antibacterial activity against the Gram-negative bacterium P.fluorescens. No antibacterial activity against the Gram-positive bacteria B.subtilis, B.cereus, B.megaterium, M.phei and S.aureus, or against the Gram-negative bacteria E.aerogenes, E.coli, P.aeruginosa, P.fluorescens and P.vulgaris."}]}
+{"id": "function_test_3088", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "AGETHTVMINHAGRGAPKLVVGGKKLS", "output": "Has antifungal activity against B.cinera, F.oxysporum and P.piricola with IC(50) values of 15.2 uM, 12.4 uM and 18.1 uM, respectively. Lacks hemagglutinating activity towards rabbit erythrocytes. Lacks deoxyribonuclease, ribonuclease and protease inhibitory activities."}]}
+{"id": "function_test_3089", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "AGESSNEAKGMWFGPRL", "output": "Myoactive."}]}
+{"id": "function_test_3090", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "PQVGLIPFPRV", "output": "Mediates visceral muscle contractile activity (myotropic activity)."}]}
+{"id": "function_test_3091", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAQMTMVQAINDALKTELKNDQDVLIFGEDVGVNGGVFRVTEGLQKEFGEDRVFDTPLAESGIGGLAMGLAVEGFRPVMEVQFLGFVFEVFDAIAGQIARTRFRSGGTKTAPVTIRSPFGGGVHTPELHADNLEGILAQSPGLKVVIPSGPYDAKGLLISSIRSNDPVVYLEHMKLYRSFREEVPEEEYTIDIGKANVKKEGNDISIITYGAMVQESMKAAEELEKDGYSVEVIDLRTVQPIDVDTIVASVEKTGRAVVVQEAQRQAGVGAAVVAELSERAILSLEAPIGRVAAADTIYPFTQAENVWLPNKNDIIEKAKETLEF", "output": "The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity)."}]}
+{"id": "function_test_3092", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MWSDSLVSRICVPIIVVCTSIALLNVVSFRSECSCVVHISGAAIDIRGCSFTPDFIEYAKTLRVFNHRYQE", "output": "Plays a role in viral cell-to-cell propagation, by facilitating genome transport to neighboring plant cells through plasmosdesmata. May induce the formation of granular vesicles derived from the Endoplasmic reticulum, which align on actin filaments (By similarity)."}]}
+{"id": "function_test_3093", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MASELIEQKLALLPSQPGSYQMKDKNGKIIYVGKAKNLKNRVRSYFKAEHTGKTAELVANIHDFEFIVTNSDKEAFLLENTLIKRYRPYFNIRLKFSGSYPYIEITNERDPRLILANTLKHDHGTYFGPYPNVYAASETLHFLEMTYPLRRCNGYQGRPCLYYSMGQCLGACWRTVPQEEYQKNIDAITRFLNGETGKAISDIKKKMKRASDSTEYELAADFRDRLKFIDQTVESQRVLQNDHTPRDLFNFYMDKGWMTIEIFFLRQGRLLRQQKETLALADSVKEELESYIQQFYSQKNAQKPKEVLVPKNVDTKLLAETLEIPVRTPVRGEKRDLLKLAAKNARITLEDKFRLMELNEEKTTGAMKEITDALKIPHGYRFEAFDHSNTQGSNYVSALVVFEDGLPNKNLYRRYKLRTPTGQDEAKATFEVITRRYTRLRDEGQMYPDLILMDGGEIQLHSAEAALRKLDIDIPVAAMVKNDKHQTADLLNSRGENLFLDPHSQGFYLLQRIQDEVHRFVITFHRQLRTKTNLSSRLDEIAGIGPKSRVKLMRRFGSLPKIADASIEDIEALGIGEKVATLVKVSVSAMVKSENKKIIAKRKFEKE", "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision."}]}
+{"id": "function_test_3094", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGGGVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIVKAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI", "output": "Binds to the 23S rRNA."}]}
+{"id": "function_test_3095", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNACLVGIWLWLPLLFTWLSPEVSSSWWYMRATSGSSRVMCDNVPGLVSHQRQLCHRHPDVMRAIGLGVTEWTMECQHQFRQHRWNCNTLDRDHSLFGRVLLRSSRESAFVYAISSAGVVFAITRACSQGELKSCSCDPKKKGTAKDNKGTFDWGGCSDNIDYGIKFARAFVDAKERKGKDARALMNLHNNRAGRKAVKRFLKQECKCHGVSGSCTLRTCWLAMADFRKTGNYLWRKYNGAIQVVMNQDGTGFTVANKRFKKPTKNDLVYFENSPDYCIRDRDAGSLGTAGRVCNLTSRGMDSCEVMCCGRGYDTSHITRKTKCECKFHWCCAVRCQDCVEALDVHTCKAPKSPDWAAPT", "output": "Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity)."}]}
+{"id": "function_test_3096", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGLNIRVIAPDRIVWNAKAEEVILPTSTGQLGILSGHAPLLTALDIGVMRVRITNTWTSIVLFGGFAEVENDEILILVNGAEEASVINLDKANKELIESSSLLNEAKTNKEKFEATQKLRKAKARVQAANTLTNQSIY", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane."}]}
+{"id": "function_test_3097", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSESEQLLEKQQDHKWDAATHADKGITIKTGKIAVSSSDIPLRNRKGLLTWDQLEPWQQDNQYIISGYRPPSFSFYLCVKSIFHVHNESVNIWTHLFGAIVFLFFIFKSELILKRDTTTAEDVYVITVFLFSAFTMLGCSTFYHTISNHSDDVSKFGNKLDYLGIVVMIVGSFIPCLHYAFACHANFRTLYIGTIIGIGVIVASTCLLDRFRQPEWRPYRALIFVLMGLFGIFPVIHALKIFSFSEILVRMGLVWLLLQGLFYIVGAVIYALRIPEKWSPGKYDVFGSSHQWFHVCVIIAAFCHFHGVCIAYDYFHERRGCGEM", "output": "Probable receptor, which may be involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation."}]}
+{"id": "function_test_3098", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MARLTKRQKAIREKIDPAQQYPVAEALGLLRELPGAKFTESVEVAVNLGVDPRKSDQIVRGSTVLPNGTGKTVRVAVFAQGDAAEAAKEAGADIVGMDDLAEQVKGGNLDFDVVVAAPDAMGVVGRLGPILGPRGLMPNPKVGTVTPDVAGAVKNAKAGQVRYRTDKGGIIHCAIGKVDFEVEALQQNLQALITDLQKLKPANSKGVYLKKVAVSTTMGPGLAVDLASLET", "output": "Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.; "}]}
+{"id": "function_test_3099", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MALKTFKPTSPGRRALVLVDRSALHKGRPEKTLVEGLTKKGGRNNMGRITARRRGGGAKRLYRLVDFKRRKWDMPATVERLEYDPNRTAFIALIKYEDGEKAYILAPQRLSEGDTVIASAKCDVKPGNAMPLKAVPVGTILHNVEMKPEKGGQIARSAGAYVQLVGRDAGYAQIRLASGELRMVSDKCMATVGAVSNPDHLNINLGKAGRNRHLGKRPSVRGVVMNPVDHPHGGGEGRTSGGRHPVTPWGKPTKGAKTRKNKSTDKFIIRSRHERKKR", "output": "One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome."}]}
+{"id": "function_test_3100", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNAITQRDSKSFTGRKRIRKSFARIGDVVPMPNLIDVQRASYEAFLQMNVHPDNRTPTGLQEVFRSVFPIDDFAGRGRLEFVNYELEEPKYDVEECIQRGMTFAAPLKVILRLIVWDVDEDTGSRSIRDIKEQPVYMGDMPLMTDNGTFIINGTERVIVSQMHRSPGVFFDHDKGKTHSSGKFLFAARVIPYRGSWLDFEFDSKDLVYVRIDRRRKLPVTTLLYALEGQRTEAAIASGTDPQDLPEIHGMTAEEILSYFYTQVVFTSTPKGWARPFDPEAFRGITLAEALIDADTGTVVAEAGTKLTARSARKIAEQAKTVLVGRADLLGRYMAEDLVNDQTGEIYAEAGEELTEARLAALETLGVTSLPTLAVDQTTGPWIRNTLAIDKNSTRDDALIDIYRVMRPGEPPTPETAEALFRGLFFDMDRYDLSSVGRVKMNMRLGVDAPDTVRTLRKEDILRTVKILCDLKDGRGAIDDIDNLGNRRVRSVGELMENQYRLGLLRMERAIRERMGSVDIDTVMPHDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEVTHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATYAKVNKYGFIETPYRMVEDGKVSDQWRYLSAMEEDRLVVAQADAPRDSTGKLTEELISVRRQGDFRLVKPEDVTSMDVSPKQLVSVAAALIPFLENDDANRALMGSNMQRQAVPLIRADAPLVGTGMEAAVARDSGATIVARRAGVVDQIDGARIVVRASGEDGATQGVDIYRLRKFMRSNQSTCINQRPLVKVGDHVISGDIIADGPSTELGELALGRNVLCAFMPWNGYNFEDSILISERIARDDVFTSIHIEEFEVMARDTKLGQEEITRDIPNVGEEALRNLDEAGIVYIGAEVNPGDILVGKVTPKGESPMTPEEKLLRAIFGEKASDVRDTSLKLPPGTTGTIVDVRVFSRRGVDKDERAMAIERAEIERLAKDRDDERGIQERAFLNRLREKLMGHPASGGFKGIKAGTIITDEVLAEHPRGAWRNISVQDDAVVADIELLKREFDAAVAKIQARFEGKVEKLQRGDELPPGVMKMVKVFVAVKRKLQPGDKMAGRHGNKGVVSRVVPVEDMPFLEDGTPVDLVLNPLGVPSRMNVGQILETHLGWACANLGRQIGELVEDYRRNGQQRDELLSRLREIYGENVYNDVIADMNNDQLIELAENLRKGVPIATPVFDGARPSDIENMLSRAGLDTSGQVVLTDGRTGEPFERKVTVGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVSGRTKVYEAIVRDQDSFEAGIPESFNVLMKELKSLGLNVDLENRSA", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_3101", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSQEFAHLSVLLEETVGGLNIKDDGIYIDGTFGRGGHSRQILQRLGENGRLIAIDRDPQAIEAAKQFADDPRFQIVHGGFGQLADYVEELGLVGKIDGVLLDLGVSSPQLDDAERGFSFLRDGPLDMRMDNSQGETAAQWLARAEIEDMAWVFKTYGEEKNARHIARCIAADRDKTPFLRTKDLADLIARITKNKERNKHPATRVFQAIRIYINSELDQIDQALEGALTVLAPQGRLSIISFHSLEDRIVKRFIRRHSQGESVPHGLPITEDQINKSRKLRAIGKAIMPSDEEIERNARARSSVLRIAERLDY", "output": "Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA."}]}
+{"id": "function_test_3102", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRTSKYLLSTLKETPNDAQVVSHQLMLRAGMIRPLASGLYNWLPTGLRVLKKVENIVREEMNKSGAIEVEMPVVQPAELWQESQRWEQYGPELLRFVDRGNRDFVLGPTHEEVITDLVHREVSSYKQLPLNLYQIQTKFRDEVRPRFGVMRGREFLMKDAYSFHTSKECLQNTYDVMYRTYNNIFTRLGLDFRAVQADTGSIGGSASHEFQVLAKSGEDDIVFSSNSDYAANIELAEAVAIGQRQAPSATMELVDTPNAKTINDLVEQFNLSVEKTVKTLIVKGANEGQPLIALIVRGDHELNEVKAQKLPEVADPLEFANEDEIKTKIGASIGSLGPVNLPIPAIIDRSVALMSDFSTGANIDGKHYFNVNWDRDVALPKVADLRNVVEGDPSPDGKGTLQIKRGIEVGHIFQLGTKYSEAMKATVQGEDGRPQTMIMGCYGIGVSRVVAATIEQCHDEKGIIWSSDEIAPFTVAIIPMNMYKSKNVQIFAEELYQSLLNKNVDVIFDDRKERPGVMFADMELIGVPHMIVIGEKNLEKGEIEYKNRRTGEKQIIAKEQVLDFLAQRVNA", "output": "Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS."}]}
+{"id": "function_test_3103", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEDYKAFLDEKMSKVLLSLDNEYKTLRTGRISSNIFDKIFIQYHGQRTPITQVSSIRIPEARLVVIQPWDKTILNKIEQAILNSDLSMNPSSDGSVIRIKVPALTSERRQDIVKHAKKIAEEHKISTRNIRQDLNNKVKKQEKESEITEDSLKRILDDIQKSTDIYIKKIDAILESKIQEIMEV", "output": "Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another."}]}
+{"id": "function_test_3104", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEFVATCMPGLADLLSDELGSLGISVTETGRAHVSFSGGVADALKVCLWSRLSERVLLHLATLGVTPDIAPEKLAASQDWLSLVGNNAPVHLHIEHGAEVRGDNRISAKRFIHALPEQFAISREPKGSCCIRARLDLNEAHLWLDLAGEPLHRRGYRLAGGRAPLRETLAAAILWAVGWGKEGRHSALIDPFCGSGTLVIEAALIAAGRAAGAQRQHYGFQQWRGCRRQLWLDAQKEAGESGKRPVPAVSLKGFDSEASTLQLALQNAERAGVRNAIHFERRELGALRRRDFVDNGIVVGNPPWGERLEEKPQAGWLHYALGRILSVRAPGYQALLLGADAEVMDRSGMNLEQQWRLKNGPFNNFIRLYSPRKQTPANVVKVADDSAFNVPEGAQPLLNRLRKNGKHLRRWLEREDIQCYRLYDRDLPEFNVAVDIYADQVLVQEFKAPKTIDPEKAKERRDWAVTAVRAALGVHREQVHLRTREKQKGNQQYQKLDAQGQYRVVREGQSQLLINLQDYLDTGLFLDHRPTRLRIAEEASGKRFLNLFAYTGSATVHAAVGGAKRTVTVDSSKRYLDWAACNLAANGFSTDQHELARADTMRWLDECKEQFDLVFCDPPTFSNNKSRSDFVVEEHHGDLIRKIMRCLEPGGVLYFSCNYRRFQMDESISKWYAVEDISRWSIPEDFRRNEKIHYCYAIRHVEDA", "output": "Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA."}]}
+{"id": "function_test_3105", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MHTGAFMSDQQDRIYATSHSQVGRFSFDDTVVRVFPDMIRRSVPGYPTIIDMIGVLAARYAQPDTCLYDLGCSLGAAATAMATLTGDTGNPIVAVDNSRAMIEQAENLLSQAGQAHRVTLQEGDVAEMAFNSCSMAVLNFTLQFIALEKRDALIRRLADATVPGGILVLSEKIRFANDAENALQTELHHAFKRNNGYSDLEISQKRNALENVLIPETLAAHETRLKKAGYRQIHVWFRCFNFVSLLAVR", "output": "Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)."}]}
+{"id": "function_test_3106", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTSIILIPARMASTRLPGKPLADIAGRTMIAQVVARALESGVGRVVVATDTEEVAAAARAEGVEAVMTRADHQSGSDRIFEALQTIDPGATAEIVINLQGDLPTIPPEDIRAVVRPLENADTDIATLGVEISDEEEKANPNVVKIVGVPVKTASDALRLRALYFTRATAPWGEGPLFHHIGIYAYRRRALERFVALPPGTLEMRERLEQLRALEAGMRIEAEIVRSVPLGVDTPADLERARQLLSARTESR", "output": "Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria."}]}
+{"id": "function_test_3107", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIETTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIDEIESIVVHIENEINKCFIEEIETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK", "output": "Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes."}]}
+{"id": "function_test_3108", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNEVKCVFETKLSPGDVAKLNKIVGAVVPVARCTPLISPRDVGLHKHVSHRTDYGKLHMALNMMYPTVFRKLEGNQMVMTPMQHGNIYTIRNTGPFSWEVGDRLAIIPPVFSVEHTTIMQTPSWDLMLPIIVPVQVAKEINIRNLVLTLMSLNRPGRDVELSQEVRRIHFRDVTIDIPATLDTRQLNSVRNVCLALALITNVAPSLLQQYVPRLALAETDMLLVKCYDLLKKLDLPGDGNGGEPPNIPNEIQRMSGLLNLITYVSSIVTENSLFIVNDITPDNKMATCTFTL", "output": "Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly."}]}
+{"id": "function_test_3109", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MARIAGVDLPREKRIEVALTYIYGIGRSTARRVIRETGVDPDTRVRDLAEGEIAALRRYIDENLKVEGDLKREVNQNIRRLMDIGCYRGLRHRRGLPVRGQRTKTNARQRKGPRPAIGGRKK", "output": "Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites."}]}
+{"id": "function_test_3110", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MHCPFCAAVDTKVIDSRLVSDGSQVRRRRQCLDCNERFTTFEVAELVLPRVIKSDEVREPFNEEKLRRGMLKALEKRPVSSDDVETAISHIKSQLRATGEREVPTKMVGNLVMEALKRLDKVAYIRFASVYRSFEDVREFGEEIARLQD", "output": "Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes."}]}
+{"id": "function_test_3111", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAKLTKRMRVIRDKVDVTKQYDINEAVALLKELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFAQGANAEAAKEAGAELVGMDDLADQIKKGEMNFDVVIASPDAMRVVGQLGQILGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKVDFDSDKLKENLESLVVALKKAKPATAKGIYIKKISLSTTMGAGVAIDQSGLTAVVN", "output": "Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.; "}]}
+{"id": "function_test_3112", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKEEIDAPVSTDASGTDLENARDQPSGEKPTAVDIYLVEWDGPNDPELPMNFPLWKKSLITCIFSTLTIWVTFSSSVFSAAAGITSKEFHVSVEVMTLGTSLTVLGFTVGPLVWGPMSELYGRLKPLYIGYAIFIIFQVPVAVAQNLETLMLARFFLGFFGTSALAIIPGALADFWGPVERAIAISLFSAATFVGPIFGPIMYVNTMITLVNGVWTRANHDMSSGGFIVDSSLGWRWTAWITMIPASFFGIIAFLTLPETYHPVLLQRRASRLRKETRIWAYHSRLDENTPTFGEILTKYLFRPIQMLFLEPILVCMTIYISLIYGILYLFFVAYPIAFREVRNWKSLGIAALPFLGILVGVLMGCLLVTIATRLWYAPKLQNGSVVPEDRLPPMIVAAILLPIGLFWFGWTSSPSISWAPQAIAGAPIGMGILMIWMQGLNYLIDVYLVVANSAMSANTLIRSAVSAAFPLFATAMYHKLGVDWATSLLGFLSIAMIPIPVIFYFYGAKIRALSRFSPKW", "output": "MFS transporter; part of the gene cluster that mediates the biosynthesis the mycotoxin citrinin, a hepato-nephrotoxic compound to humans due to inhibition of respiration complex III ."}]}
+{"id": "function_test_3113", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MERAIFAGGCFWCMGQPFEEQAGILSVRSGYTGGHLPNPSYEQVCAKTTGHTEAVEIIFDPKQIAYKDLVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTTERQKEIAEQSKANLQASGRFDQPIVTTIEPAEPFYLAEDYHQGFYKKNPKRYAQSSAIRHQFLEENWS", "output": "Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine."}]}
+{"id": "function_test_3114", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSSYFVNSTFPVSLPGGQDSLLGQIPLYSSGYTDPLRHYSNAATYGAANMQEKVYPASYYQQTGAAAIYGRAGGGAPCEYNPVGTFYKETEGSCAFSSRDDQPLFVTQEHQQRKVECPEQSVSMGSSIDDKSSTLIYPWMQRMNACSAGPFGNSGRRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEISHALCLTERQIKIWFQNRRMKWKKENKLLNPSKTPEEEEEAEKKS", "output": "Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis."}]}
+{"id": "function_test_3115", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSNKGQLLQDPFLNALRKEHVPVSIYLVNGIKLQGNIESFDQYVVLLRNTVTQMVYKHAISTVVPARAVNFRVDDSSES", "output": "RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs."}]}
+{"id": "function_test_3116", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTDSSATRPPRLPRRDVHGVLLLDKPLGLSSNDALVRAKRLLRANKAGHTGTLDPLATGLLPLCFGEATKFSQDLLDADKTYEAKVRLGATTTTGDAEGEIVVERLVTCDHDALDAAVARFTGEIEQVPPMYSALKKDGKPLYEYARAGQTVERAARQVTIHAITLLDVDLPAAMFTMRVTCSKGTYIRTLAEDVGEALGCGAHLIGLRRTAVGDLTLEGAVTLEQIDAQADEARPGMLAPVDALLQRCPPVHLDAAAMGRFLQGQRIARRDLPEGQVPPDEGTLARVYGDEGRLLGVARMKEGALRPERLVKL", "output": "Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs."}]}
+{"id": "function_test_3117", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MADIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAEQKTWIQSVPYMDRLDYVSMMVNEHAYVMAIERLLGLEVPIRAQYIRVMFDEITRLLNHLMWIGSHALDVGAMAVFLYAFREREDMFDMYEAVSGARMHAAYYRPGGVYRDLPDTMPQYRASKVHNEKAIKVMNEARSGSLLDFIEDFTNRFPTYVDEYETLLTDNRIWKQRLVDIGVVTPERALQMGFTGPMLRGSGIEWDLRKKQPYEVYDKMDFDIPVGTAGDCYSRYLVRVEEMRQSNRIIKQCIDWLRRNPGPVITENHKVAPPSRVDMKSNMEELIHHFKLFTEGIHVPAGEAYAAVEHPKGEFGIYAISDGANKPYRLKIRAPGFVHLAALDEMARGHMIADAVTIIGTQDIVFGEIDR", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_3118", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFAEHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTQLIERLGLRR", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.; "}]}
+{"id": "function_test_3119", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKKPLRQQNRQIISYVPRTEPAPPEHAIKMDSFRDVWMLRGKYVAFVLMGESFLRSPAFTVPESAQRWANQIRQENEVEE", "output": "Activates the cell division inhibited by chromosomal DNA over-replication."}]}
+{"id": "function_test_3120", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVEAAETFSLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACSVVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDIISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQPELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPDTAQRVADWLGKNYLQNQEGFVHICRLDTAGARVLEN", "output": "Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate."}]}
+{"id": "function_test_3121", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAKITELDHHLNQEKEALDKVVSNLNELCEHNQKLQGFIEIQKEVKELKKEHIKSLSWFKKLINTVSNIKYVFVKSEEQLAKDAIEQNNKLLKRIDNTILSVADKSGPLKQELQKELRKNFENLAKKDLSKDQRERLSNLLNNEYAANPQKFAQLPMSKPLHFPNAEELENQHNDLKVIQQNVLNLLTENSNIEELKKIQKQVAEIREEVPFTKLEKLNNFWQKIKNIFVNNSEQVLAKNKENNTKTIINIEEKLHKANNKFFELVSNKKQDIENIISNLPDSKRLEAIKEKLQKHINVKDTNNIAEQASAAQLQSAETKPTAVVLPNNAIPTTPPVTEEKTFTPPPAPPPPMPTDNIPTPLPVSKAEATEHKNVETAASNVPPPPPPPMPTGNVPPPPPVGDNTVTSTPQKAKETNQPRPAVDTTNLMKQIQGGFNLKKIEYGEDGKPIPKNKEDTKETSDPIIAALNKIRSAKVSSDSERSNSDSGTDSGWASDVSTRSKKVLTRRERNAKQSQQR", "output": "Recruits and activates the Arp2/3 complex, which in turn leads to actin polymerization, promoting Rickettsia motility during infection."}]}
+{"id": "function_test_3122", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSIPLLKYSLSTQNQRVDGYEVSPGEEQPRAYNTDNLPSAVEMDEVIWAAYRQIFSEHQILSSTSDSNLESQLRFNQIRIKDFIRGLILSESFRKLNYDVNNNYRFVEICVQRILGRDVYNEREKLAWSVVIASKGLESFVNMLLDSDEYEENFGDSIVPYQRRRIIAQRSKGEMPFNLKTPRYGADFKEKFGMPQFIWQGPVRQFRPQEQRPKAGDPALFLGMVNDLALFK", "output": "Rod-core linker protein required for attachment of phycocyanin to allophycocyanin in cores of phycobilisomes.; "}]}
+{"id": "function_test_3123", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSKPKRERSLPDNEAKAIARMLRVSPQKLNLVAQLIRGRKASAALADLQFSRKRIAVDVKKCLESAIANAENNHDLDVDALIVSEAHVGKGIVMKRFAPRGRGRSGRIFKPFAQLTIVVRQVEAEASA", "output": "This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).; "}]}
+{"id": "function_test_3124", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAKAPASNAAQRVRKKVRKNVADGIAHVHASFNNTIITITDRQGNALSWASSGGQGFKGSRKSTPFAAQVASEVAGRAAIEQGVKNLDVEIKGPGPGRESSVRALAALGIRINMIADVTPVPHNGCRPQKRRRI", "output": "Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome."}]}
+{"id": "function_test_3125", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAQHDFAPAWLNFPTPPSSTKPFLYSDKHSEGLGRSDCAFNVNRQRHSSSDAFDSAIGRPHGGNLAKREKIAWRPQSRAGAEPTWQRDTSPHPYSMKSQLHSENNTSEIDLPRKVDREERKMFEVEDFSSLYPEHERGKNSFAAGLWEYPVSDRSRSSQMLGIKKGVKDDFSLSGYSIAAGNQSLPGKHWAGIKKEECKSLTKESSIGSSFYQDCPHEKYRPNTSLHAELLAVTPCSLEGEEDTNLNNRNGSCPERDINLNFDENKISEDNGNTLMSGQISSAYPPDGVLSSSLEAEFRLLREMGWQEDSENDETCAPLTEDEMKEFQAISEQLQKNGLRKHVFLRNALALDLFHDSVQKEDSETSSSSDTSDDE", "output": "Functions as a GC-rich promoter-specific transactivating transcription factor."}]}
+{"id": "function_test_3126", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAIMGVQMVVTLLVASIMQRVSPHYSFGRWLLCNGSLFRFKHPTEEELRTLAGKQKPKAKRERRTNGVTDEKPLTVPKDIDLRLDTQPITTIDALVLRYFLEYQWFIDFALYSTIIYLFTEAYYCVVDAQNEINIGVLWCLMSIIFSIKVLFTVMKHYFRSEEGGERSVCLTFAFFFLLIAMIVMVVRDEYLEFGLEPGLASVCHNLENFLAQRGWQWSMPFVKLAFKIALVALCAFLGGCLTFPGLRLAQTHLDALKMAADRPMLQLLLHMSFLPPVIVVVLWIRPITRDFLLNAPMGKESVELMSNSAYNTFRLWIIVVLCLLRFCLTRFHLQAYLCLADRWVEQMKREAGRISMLEIQRKISRIFCYLTVVALQYLAPIVLTFHCVLMLKSLGDYSWGLYPEPTGFTPVVDSSPVQSHSPTSEEEEDTEDVQAAVEQIMGAMSSLRGLFTPLFFRGLFSFLTWWVSVCQIVTSLFGLYFHQYLGAS", "output": "May play a role in protection against oxidative stress."}]}
+{"id": "function_test_3127", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDWAEKYRPRHLNEMVGNREALHQMSEWATRWTVESPPLILYGKPGIGKTSSAWALAHDMNWEVVELNASDQRTKAVIEKVAGGSASTGSLTGAARKLIILDEADNLQGNADRGGARAIAEVIRQARQPLILIANDLYGLDGTIRNLCTKVQFKALPAKSLVPRLREICSREQLTCSAQALTDIAEQSGGDIRSAVTMLYASAIGKDTVGEDDVSISAKDSRASIFDLVAATLGYRQVPSLLDMSMSVDETPDTILQWIEGNLGVLPDRKKTAQAYAALSRADMYLGYTFLTQYYTLWRYATSVMLYGVHDVMKGRPSGYAKIMPPSRWRQMSVAKKQKTIREQLLSDMGTSMHMSASTVRNLYLCPISLLAKQFPEQFAKSYDLDVDKLDILIHDPATSKSIIKKIEDEKKQIEKELKKKKKEEDAKGKKARGSKKEKEPIVEETPSIDSFSSQEPGNPPEQPSTEPVEKDKKSSQSTLFSF", "output": "Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA."}]}
+{"id": "function_test_3128", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKKIATATIATAGFATIAIASGNQAHASEQDNYGYNPNDPTSYSYTYTIDAQGNYHYTWKGNWHPSQLNQDNGYYSYYYYNGYNNYNNYNNGYSYNNYSRYNNYSNNNQSYNYNNYNSYNTNSYRTGGLGASYSTSSNNVQVTTTMAPSSNGRSISSGYTSGRNLYTSGQCTYYVFDRVGGKIGSTWGNASNWANAAARAGYTVNNTPKAGAIMQTTQGAYGHVAYVESVNSNGSVRVSEMNYGYGPGVVTSRTISASQAAGYNFIH", "output": "Not known; immunogenic protein."}]}
+{"id": "function_test_3129", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPGLPTPRRLVASVNYRRTRTVEDSRMPLTEHLRELRNRVAIALLAFAIAGVVCFIFEPRIFDWLKAPYCDLPASKRFSPDGLAANDCTLYFFGILDAFTIRLKISMIAAVVVSSPVWLYQLWSFITPGLHRHERRWSLTFVGVSLVLFATGAVFAYLTLSTGLGLLLGFGGNGLVSVLDGNRYLSYVQAMLLIFGLSFEVPLLVMMLNLAGIVSTAKLRSWRRPEIFLVFVFAAVVTPSQDPFTMLALGLPMVLLYEVALIIGWLNDRRVARRGDTSPYADLDDDETSPLDFDDAPPRPAASAGPAATATSPGTANPPGTANPPGTANPVGTANPVGTGSSTPVGAGTAPVSPSTDVTHGDIT", "output": "Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides."}]}
+{"id": "function_test_3130", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGQKIHPTGFRLAVTRNWSSRWYADDKDFGGMLAEDIRVREYLKKKLKSASVGRVVIERPAKNARITVYSARPGVVIGKRGEDIESLKADLQRLMGVPVHVNIEEIRKPETDAQLIADSISQQLEKRIMFRRAMKRAMQNAMRLGAQGIKIMSSGRLNGIEIARTEWYREGRVPLHTLKANIDYGTSEAHTTYGVIGIKVWVYKGDMLANGELPVETAAPREEERRPRRAPRGDRPDGARNGRPGGGRGRAPRKADAAPAPEGE", "output": "Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation."}]}
+{"id": "function_test_3131", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKISTTRFGMIEISESDIILMRRGILGFEESKKYALLYQDVKNPFLWFQSLDDGATAFVVIDPFLLQPYYQPELNDDTLEKLEIDNPEDVALMVIVSIRSNPVLLTANLRAPIVINAAKKKACQVVLEDSRFPIRYDILKNREFLLGGHCYEISATAP", "output": "Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum."}]}
+{"id": "function_test_3132", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLTLPKYLRSELKKPLGQLYKSIDIIEEKLHQQLSEDKLIISIGDATTKNLIKLNIQPQICIVDNKIEREPVEHKLTHTDNLVHVNNPAGCITDELVKICIDSINTATSNNPVIIEVKGEEDLAVLPCILNAPKDTFILYGQPKEGVVLVCVNEAFNKAKHFYKQLNKE", "output": "Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA)."}]}
+{"id": "function_test_3133", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAERNEQILTPSQLNALARDLLEGSFPLVWVEAELSSVTRPSSGHLYFTLKDARAQIRCAMFKPKSTWLKFQPREGLRVLARGRLTLYEARGDYQLVLDHMEEAGEGALRRAFDALRARLAAEGLFDAERKQSLPAHVQRLAVITSPSGAAVRDVLSVLARRFPLLEVDLLPSLVQGDSAAAQITSLLQRADASGRYDVILITRGGGSLEDLWAFNDERLARAIAAAQTPVVSAVGHETDFSLSDFVADVRAPTPSVAAELLVPDQRELVPRVRRAQARMTQLQQHALGNAMQRADRLALRLRAHSPQARLQLLHRRQEEAGRQLGARMTQVLERLQARVQRGHAQVQSHNPQRHLAGLQQRLRALHPQAAMQRRLQHDQLQLRSIARSLEAVNPLATVARGYAIVTRPADGSVVRSAAEVAAGERLRAQLADGSIEVRVEPGER", "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."}]}
+{"id": "function_test_3134", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFSPLTDLSRARILLSNDDGFEAEGLAVLERVARTLSDDVWIVAPETEQSGAGHALTIHDPLRFRARGEKRFSVRGTPTDCVLVAVNHLMDRPPDLVVSGINRGGNLGEDVHYSGTVAAAMEGTLLGLRAIALSQVFETNGTGIADPFQVAATHASDVIRRVCGRPWNRQVLINVNFPDCPLDAVTGIELKRQGRRKMGDDIEERRDPRDRPYLWIGAQRKEDRKTAGTDMEAISRGAITVTPLCVDMTDLPTIEALTGAF", "output": "Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates."}]}
+{"id": "function_test_3135", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFKLFSTKYMRSAPVVAAAWITMTAGIIIEFNRFFPDLLFHPMS", "output": "May help in the organization of the PsaE and PsaF subunits."}]}
+{"id": "function_test_3136", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MALPEHLQRHLEAGRALTAAGGYRGRFAPSPTGLLHLGNLQTALLSWLAARQAGGAWLLRIDDLDTPRNRAGAIEAIQSDLRWLGLKWDGPVLLQSERRGIYHSWLSWLRRSGRLFACRCSRRELADQPIYSGFCRQAVHNWGWQRQRLPSWRLRVADDDPHGSGDVVLRRADGFIAYQLATVIDELSFGINDVVRGADLREALPAQRSLFAALGEAPPRFRHGPLLCDASGQKLSKREACAGLKPLRDAGLDAAAVIGRLASGLQLVAPEARISATELLEHLTQQAINAVIS", "output": "Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon."}]}
+{"id": "function_test_3137", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSIETLVEEIGKLTLTEASELVKSLEEKFGVSAAPAVVAGVAAAAPAAAAAEEQTEFDVVLTAAGESKINVIKVVRAITGLGLKEAKDMVDGAPKTVKEAVSKDEAEKLMKELKDAGASVELK", "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation."}]}
+{"id": "function_test_3138", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MHCPFCQHNDTRVIDSRVSEDGTTIRRRRECEACGERFSTLETIELKLPTVVKSDGGREAFDARKLRTSFDRALQKRPVAEEQIEAAVRAVVHQLRMSGEREVGSLRVGEYVMVELRKLDHVGYVRFASVYRSFQDVADFREEIEKLERELPVGSEQLPLLEAALERAGKPGKR", "output": "Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes."}]}
+{"id": "function_test_3139", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MALLQIAEPGQSPQPHQRRLAVGIDLGTTNSLVAALRSGLSEPLADAEGRVILPSAVRYHADRVEVGESAKLAASSDPLNTVLSVKRLMGRGLSDVKQLGDQLPYRFVGGESHMPFIDTVQGPKSPVEVSADILKVLRQRAEATLGGELVGAVITVPAYFDDAQRQATKDAAKLAGLNVLRLLNEPTAAAVAYGLDQHAEGLVAIYDLGGGTFDISILRLTGGVFEVLATGGDSALGGDDFDHAIAGWIIESASLSADLDPGAQRSLLQAACAAKEALTDSDSVEVAYGDWKAQLTREAFDALIEPMVARSLKACRRAVRDSGVELEDVHAVVMVGGSTRVPRVREAVAEAFGRQPLTEIDPDQVVAIGAAIQADTLAGNKRDGGELLLLDVIPLSLGLETMGGLMEKVIPRNTTIPVARAQDFTTYKDGQSAMAIHVLQGERELISDCRSLARFELRGIPAMVAGAAKIRVTFQVDADGLLSVSARELGSGVEASIQVKPSYGLTDGEIAKMLKDSFQHANDDKVARVLREQQVDAQRLIEAVQGALEADGERLLDAEERMVIDLQVQELTELMKGTDGYAIEQQTKRLSQVTDAFAARRMDQTVKAALSGRNLNEIEDI", "output": "Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB."}]}
+{"id": "function_test_3140", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSKEDSFEMEGTVVDTLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVRVELTPYDLSKGRITYRAR", "output": "One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex."}]}
+{"id": "function_test_3141", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPLRSTFTRFFQLEAASGLLLIAAAILALIINNSPLSWLYNGLLDTPVVAQIGALKIAKPLLLWINDGLMALFFLLIGLEVKREVLDGQLSKPSQIVLPGAAAIGGMLVPALIYWFLNRDNPAALDGWAIPTATDIAFALGVLALLGKRVPVSLKLFLMTLAIIDDLGAIVIIAIFYSGELSTLSLGLAAACIAALVAMNRLGVVKLGPYMIIGLILWVCVLKSGVHATLAGVTLAFCIPLRTKNAEPSPLLTLEHALHPWVAYGILPLFAFANAGLSLSGVTVESFTHHVPMGIAVGLLLGKTLGVFGLTWLAVKTGIAALPQGANWGQVLGVAILCGIGFTMSLFVGSLAFVPGASEYAGMDRMGILTGSVFAALIGYAVTAAASRKNTALPS", "output": "Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons."}]}
+{"id": "function_test_3142", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MATDTTEVKAIARFIRMSPYKVRRVLDQIRGLSYREALIILEFMPYRATEPVLTLLRSAAANAEHNAGLDRAELVITQAYADQGPVLKRFQPRAQGRAYQIRKPTCHITLAVAANAGAK", "output": "This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).; "}]}
+{"id": "function_test_3143", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRLLPLFLMVTLAASGCGIVESKKIDYKSSNKLPTLEIPPDLVAPTADNRYAIPDTEGSGTATLSTYSAERKAAPSGTPSLLPAQDKARIERAGTQRWLVVQATPQQVWPVIKDFWQENGFIVNLESPETGVIETDWAENRAKIPQDVIRRTLGKVLDGLYSTAERDKFRTRIEAGSGGTEIYLSHRGMMEVYATEGKDKTVWQPRPADPELEAEMLRRLMLRFGVEENRAQTLLTAKQTPDQARVIRDAGGSLLEMDEGFDRAWRRVGLALDRVGFAVEDRDRSKGTYFVRYIDPDADNASKRDEGMFAKLAFWRSKKDQASPQLQIVVDEAGEGKSRVRVAGGEGRAADAATQNRIINLLHKELK", "output": "Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane."}]}
+{"id": "function_test_3144", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQIDEHHAVRTDAGMFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVYYFTEDFFRLVVNSATREKDLSWITQHAEPFGIEITVRDDLSMIAVQGPNAQAKAATLFNDAQRQAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIALPNEKAADFWRALVEAGVKPCGLGARDTLRLEAGMNLYGQEMDETISPLAANMGWTIAWEPADRDFIGREALEVQREHGTEKLVGLVMTEKGVLRNELPVRFTDAQGNQHEGIITSGTFSPTLGYSIALARVLEGIGETAIVQIRNREMSVKVTKPVFVRNGKAVA", "output": "The glycine cleavage system catalyzes the degradation of glycine."}]}
+{"id": "function_test_3145", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLAFCRSSLKSKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNKTLARLAQQHPVVVLFRHAERCDRSTNQCLSDKTGITVKGTQDARELGNAFSADIPDFDLYSSNTVRTIQSATWFSAGKKLTVDKRLLQCGNEIYSAIKDLQSKAPDKNIVIFTHNHCLTYIAKNKRDATFKPDYLDGLVMHVEKGKVYLDGEFVNH", "output": "Catalyzes the dephosphorylation of heptose(II) of the outer membrane lipopolysaccharide core."}]}
+{"id": "function_test_3146", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKVKAVAKQVPVTPRKXRLVVDLIRGKKIKEAESILMFTPRSASPILAKLLKSAVANSVHNFNFNIDDLYVEEIFVNEGIRLPRLFPRAKG", "output": "This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).; "}]}
+{"id": "function_test_3147", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSFGSPGGRSVNIKPKPPERGSFPLDHDGECKFIISSYLQCLKKGGGVNDETCRKLAKSYLSCRMDHNLMAPECFENLGLVFDEDKKKREEASASTTAASESKKPST", "output": "Required for the assembly of mitochondrial cytochrome c oxidase."}]}
+{"id": "function_test_3148", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSDKHINLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALVPKFLELIEQTNENRRVALVVDMRSRLFFKEINSTLDSIESNPSIDFRILFLDATDGELVSRYKETRRSHPLAADGRVLDGIRLERELLSPLKSMSQHVVDTTKLTPRQLRKTISDQFSEGSNQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYKVELREKTGLDEDVFNYVMSHPESEVFYKHLLNLIVPILPAYQKEGKSVLTVAIGCTGGQHRSVAFAHCLAESLATDWSVNESHRDQNRRKETVNRS", "output": "Displays ATPase and GTPase activities."}]}
+{"id": "function_test_3149", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNHIYKLKSYGIGTDRRFYGVANKTLETPDFLDPVRESFDWFLHVGIPEAFDRIFPIVSANGKLEISFRRGSLRVEKPENEYLAIREAKIKGKTYSARVYVTLVKVHSEDGEMEEQEILLAEFPFMTQGGTFIINGFEKVVVSQLIRSPGVCFRENVRNQQADDLFNKVEIIPQLGSWMEIFHKVTGNQVDTVKFRIDKHKNIPLLSFLRAIGFTNETVRKYFGNSPELLESIRRHKLESLEENLELIYRIVRKDDRITEEGLKNLIPSIIFNERRYNLASTGRFMLNAKLNLVERISQTYLAEDLVSKKNKILFKKGTYITRQLALEIQEKFNNEEIPLSEIEGVDSTIYARQLEITRNENLWKRFYVAIVKVWPNKKSMLQESEPVNVIATDPNLNEKTLVLSDIIAIVSYYFNLLSNLGKSDDPDSLVNKRIVSVGELLQNQFLIALTKIEKNSKEKISTKSDLSQLTVKSIINNKPIYNQFKNFFNSSKLSQFMDQINPLGEMASKRKVTSLGPGGLNRDTAQFEVRDVHTTHYGRICPVETPEGQNIGLILNFSVFSRINQYGFIITPYYQVKNRIVDYSKVHWLAASEEFDKSFAQSGVEIDQNNRIIPDKLTVRKNQTYLVLDAEQVNYIDVSSMQMTSISASAIPFLENNDANRALMGSNMQRQAVPLIKSEAPLVATGIEEAVARFSATNLRASISGKVTYVDAKKIIIDDGEKPEIHYLRYFEKSNQETLILQKPTVKVGDKVKKGQLICDGPSTDNGELALGKNVLVAFSTWYGYNYEDAIIISEKLVKDDVFTSIHIQEQTIKFRSTKAGNDILTAEIPNASAKSRLHLDANGIVIVGSEVDTGDILVGRTSPKGEDNPTAEEKLMAAIWGKKALAQKDTSLRVKNGEGGTVIDVQILSRDQGDNLEEGVGMLIKILIAQKRKIKVGDKMAGRHGNKGVVSVILPVEDMPFLEDGTPVDIVLNPQGVPSRMNIGQVLELHLGMVAKKLKTKFVTPVFDGIKIETIKKLFDEANIPESGKFKLFDGISGQPFENPVSVGYMYMLKLLHMVDDKMHARSIGPYSLTTQQPLGGKSQNGGQRFGEMETWALESFGATSVLSELLTYKSDNIQGRNLLYNNIISGGKIPSPGTPESFNVLAYELRGLLIKLEVHKNDQENQEVEEIKDPLELPEIPSNFIDEYNQDGRIELNKLEEFADFDEENIDFDKLTR", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_test_3150", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSEISVTQTLNTLGLRCPEPVMLVRKNIRHLNDGEILLIIADDPATTRDIPSFCQFMDHTLLQSEVEKPPFKYWVKRGK", "output": "Sulfur carrier protein which probably makes part of a sulfur-relay system."}]}
+{"id": "function_test_3151", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MATLSVKPSQRFQLPDWHTNSYLLSTNAQLQRDASHQIRQEARVLRNETNNQTIWDEHDNRTRLVERIDTVNRWKEMLDKCLTDLDAEIDALTQMKDSAGQNLQAKNLPLDVAIECLTLRESRRDIDVVKDPVEDELHKEVEVIEATKKALQQKVSQAFEHLCLLQEVRQQLNSDHRGKMETLEIDRGCLSLNLRSPNISLKVDPTRVPDGSTTLQQWDDFSQFNKDRGEAEMKAATELREAIALTIAETNNELEAQRVATEFAFRKRLREMEKVYSELKWQEKNTLEEIAELQEDIRHLEEDLRTKFLSLKLSHTRLEARTYRPNVELCRDQAQYGLTDEVHQLEATIAALKQKLAQAQDALDALYKHLARLQADIACKANSMLLDTKCMDTRRKLTVPAEKFVPEVDTFTRTTNSTLSPLKSCQLELA", "output": "Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules."}]}
+{"id": "function_test_3152", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLIAICVQDEISAIVLDPGFSTTRAGFAGEDTPKSVIPTYYGKYTYEAQEKLIFGDDIFVTPRPGLSIHNPMGRDGVVEDWDMAEKVWEYSFTSRLTGPKAGNPFQNGLNDVANGELPSEMEGVETEEKPLADSPLLMTECGWNPTKAREKTVEIAMEKWGTPAFYLARNGVLAAFAAGKASALVVDVGASNISVTPVHDGMILKRGVQHSPLGGDYISSQLRALFKTNSPQPITITPHYLVASKTAVDAGQPAQAKYKTFPPDKAPDASYRTLMEERTLSEFKECVVQVWPGPNKLSATGPNGVSNEEVAKSSPGRPFEFPDGYNQVFGIDRYRVVESLFDAKAAIPDPESVFPAPTQAQTVPELIKAALNGVDVDVRPHLLANVVVTGASSLLYGFTDRLNQELMQSYPGPRVRISASGNTAERKFGSWVGGSILASLGTFHQMWISKKEYDEHGPNIVEKRCK", "output": "Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair (By similarity)."}]}
+{"id": "function_test_3153", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDKSSGELVTLTPNNNNTVQPVALMRLGVFVPTLKSLKNSKKNTLSRTDATEELTRLSLARAEGFDKVEITGPRLDMDNDFKTWVGIIHSFARHNVIGDKVELPFVEFAKLCGIPSSQSSRRLRERISPSLKRIAGTVISFSRTDEKHTREYITHLVQSAYYDTERDIVQLQADPRLFELYQFDRKVLLQLKAINALKRRESAQALYTFIESLPRDPAPISLARLRARLNLKSPVFSQNQTVRRAMEQLREIGYLDYTEIQRGRTKFFCIHYRRPRLKAPNDESKENPLQPSPAEKVSPEMAEKLALPEKLGITLDDLEKLFKSR", "output": "This protein is essential for plasmid replication; it is involved in copy control functions. In vitro, binds to the DNA repeat units, BCDD'D'', EFG and HIJ (By similarity)."}]}
+{"id": "function_test_3154", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLDIIILVVIGGAFGAMTREFIMLMVPPLTDGFPLDILVANVVACFLLGTVTALYARKIHSRDVHTIIGTGMMGGVSTFSSFAYGSVVLASASMSAFLIAAAYVTVSVVAGYVAVLAGMKFGEKSADILHRYPPMASIIDSGLVTVESRHSVAETIERVAAKAKSMGMNVFTRVDHGAGAKEAGLGLPPTELIIFGNPQNGTVLMQDKRTIGLDLPIRALAWEDGSGKVWLTVNDPAWLAQRHSLGLSSDVAIKAMVTGTGTVTKYAAGD", "output": "Important for reducing fluoride concentration in the cell, thus reducing its toxicity."}]}
+{"id": "function_test_3155", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEILYNIFTIFFNQVMTNAPLLLGIVTCLGYILLRKSVSVIIKGTIKTIIGFMLLQAGSGILTSTFKPVVAKMSEVYGINGAISDTYASMMATIERMGDAYSWVGYAVLLALALNICYVLLRRITGIRTIMLTGHIMFQQAGLIAVSFYIFGYSMWTTIICTAILVSLYWGITSNMMYKPTQEVTDGCGFSIGHQQQFASWIAYKVAPFLGKKEESVEDLKLPGWLNIFHDNIVSTAIVMTIFFGAILLSFGIDTVQAMAGKTHWTIYILQTGFSFAVAIFIITQGVRMFVAELSEAFNGISQRLIPGAVLAIDCAAIYSFAPNAVVWGFMWGTIGQLIAVGILVACGSSILIIPGFIPMFFSNATIGVFANHFGGWRAALKICLVMGMIEIFGCVWAVKLTGMSAWMGMADWSILAPPMMQGFFSLGIAFMAVIIVIALAYMFFAGRTLRAEEDAEKQLAEQSA", "output": "The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport."}]}
+{"id": "function_test_3156", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSNIIKQLEQEQMKQNVPSFRPGDTVEVKVWVVEGTKKRLQAFEGVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSIAVKRRGAVRKAKLYYLRERTGKAARIKERLN", "output": "This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site."}]}
+{"id": "function_test_3157", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDRPYDETVDIPDSEDIATPRLQQSLAENLDKLRDSYGDNSKLLTKTNSELANRSIKTASKSVIRMDSSSEKLCDRGSSDDDDDDDNDDDEDEDDDDDDENANIHDATEGVYNPADYEHLTVSSEIKEIFEYIQRYTPQTIELETKLKPFIPDYIPAVGDIDAFLKVPRPDGKPDYLGLLVLDEPCANQSDPTVLDLQLRALSKQTTTKQVTVKSLENAEHQTKAIENWIKSIADLYRTKPPPTVHYTKNMPEISQLMSEWPKSFEESISNMQLSLSQLDCSLKDYVDIICALLDIPVYNNRIHSLHLLFSLYLEFKNSQHFRQNESVIT", "output": "Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia."}]}
+{"id": "function_test_3158", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAKGQSLQDPFLNALRRERVPVSVYLVNGIKLQGTIESFDQFVVLLRNTVSQMVYKHAISTVVPARNVRVGPGGGYVQSNEGNQAEDDDVEQ", "output": "RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs."}]}
+{"id": "function_test_3159", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKQLHSNEVGVYALGGLGEVGKNTYAVEYKDEIVIIDAGIKFPDDNLLGIDYVIPDYTYLEQNQDKIVGLFITHGHEDHIGGVPFLLKQINVPIYGGPLALGLIRNKLEEHHLLRTTELHEIDESSVIKSKHFEISFYLTTHSIPEAYGVIVDTPEGKIVHTGDFKFDFTPVGEPANIAKMAQLGHEGVLCLLSDSTNALVPDFTLSEREVGQNVDKIFRNCKGRIIFATFASNIYRVQQAVEAAIKYNRKIVTFGRSMENNIKIGMELGYIKAPPETFIEPNKINSVPKHELLILCTGSQGEPMAALSRIANGTHKQIKIIPEDTVVFSSSPIPGNTKSINRTINALYKAGADVIHSKISNIHTSGHGSQGDQQLMLRLIQPKYFLPIHGEYRMLKAHGETGVQCGVDEDNVFIFDIGDVLALTHDSARKAGRIPSGNVLVDGSGIGDIGNVVIRDRKLLSEEGLVIVVVSIDFNTNKLLSGPDIISRGFVYMRESGQLIYDAQRKIKGDVISKLNSNKDIQWHQIKSSIIETLHPYLYEKTARKPMILPVIMKVNEDK", "output": "An RNase that has 5'-3' exonuclease and possibly endoonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay (By similarity)."}]}
+{"id": "function_test_3160", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKEEKKLLLREVEEKISASQGFILLRYLGFTAAHSREFRNSLSGVSAEFEVLKKRIFFKAMQSAGFDIDSSDTSGHLGVVFAYDDAVSAAKQVLDFNKQYNDSLVFLAGRIDSANLSGKEVEAVAKLPSMKELRQQIVGLLAAPMSQVVGIMGSALSGVISCIDQKTQKN", "output": "Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors."}]}
+{"id": "function_test_3161", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSRSLKKGPYINVKLEKKVLAMNESGKKVVVKTWSRASMISPDFVGHTVAVHNGNKFIPVYVTENMVGHKLGEFAPTRTFRGHAGNKKK", "output": "Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA."}]}
+{"id": "function_test_3162", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAITAALVKELRDSTGAGMMDAKKALTETDGDMEAAVDWLRTKGLAKAAKKSGRTAAEGLVAVVVEGGKGVAVEVNSETDFVAKNSDFQEMVGKIAAAALAADDVDALLAADLGGKSVADTLTAKIATIGENMSVRRLAKLEGETVVTYVHNAATTGMGKIGVLVAMKGGDEALGKQVAMHIAAVNPAALSEAEMDPVVVEKEKQVQMDIARESGKPEAVIEKMIEGRMKKFVAESTLLSQQFVVNPDLTVGAAAAEAGAEITGFVRLEVGEGIVVEKEDFAAEVAKAAQG", "output": "Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome."}]}
+{"id": "function_test_3163", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTPEDFYMALKELGFDLSQKQKDQFQRYFELLVEWNEKINLTAITDKDEVFLKHFYDSLAPVLQGHIKNQSIQLLDIGAGAGFPSLPIKILCPNLDVTIIDSLNKRITFLNFLSDELGLSGVHFYHGRAEDFGQDKAFRAQFDIVTARAVARMQVLSELTIPFLKVGGQLIALKAAAADQELVDARNALNVLFAKPILNENYKLPNGDGRNITIIDKKKETPNKYPRRAGIPNKKPL", "output": "Specifically methylates the N7 position of a guanine in 16S rRNA."}]}
+{"id": "function_test_3164", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKMLLDDLYEIVEPITADLGYILWGIEVVGSGKLTIRIFIDHENGVSVDDCQIVSKEISAVFDVEDPVSGKYILEVSSPGMNRQIFNIIQAQALVGFNVKAVTLAPVGSQTKFKGVLERVEGNNVILNLEDGKEISFDFDELKKLRVSPDFS", "output": "Required for maturation of 30S ribosomal subunits."}]}
+{"id": "function_test_3165", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPSGRLQQQFIRLWQCCDGKTQDTTLNELADLLNCSRRHMRTLLNTMQARGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKSAVRQMLISHLGRSFRQGRHILRVLYYRPMHNLLPGTALRRSETHIARQIFSSLTRVNEENGELEADIAHHWQQISPLLWRFYLRPGIHFHHGRELEMEDVIASLTRINTLPLYSHITKIDSPTAWTLDIHLSQPDRWLPWLLGQVPAMILPREWETLANFASHPIGTGPYAVRRNTPNQLKILAFDDYFGYRALIDEVNVWVLPDISEEPACGLMLEGPIQGGEKAIESRLEEGCYYLLFDARTPRGAHPQVREWVSHVLSPTNLLYHADEPLQQLWFPAYGLLPRWHHARPGPGEKPAGLETLTLTFYREHIEHRVIARIMSALLAEHQVHLHIQEIDYDQWHAGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQNCIPRDWQDDAAQWRAGEMNLANWCQQLLANKAIVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP", "output": "Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain."}]}
+{"id": "function_test_3166", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEQAKAVAKQVRIAPRKVRLVIDLIRGKQVGEAIAILKHTPKAASPVVEKLLNSAIANAEHNYEMEPNNLVISEAYVNEGVTLKRFRPRAQGRASRINKRTSHITLVVTEKKEG", "output": "This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).; "}]}
+{"id": "function_test_3167", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIASVRGEVLEIALDHVVVEAAGVGYRLNATPSTLATLTRGAEARLYTAMIVREDSMTLYGFADTEARDLFGLLQTVSGVGPRLAMAVLAVLEPEALRKALAESNVAALTRVPGIGKRGAERMVVELRDKVNLVPVQAGPPGSTPAVAATPVREQVVEALTGLGFPLKQAEQALDTVLAEQPAADTSTALRAALSLLGKNR", "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."}]}
+{"id": "function_test_3168", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEAERLNAIESSLADLRRRAGELRGYLDYDVKSERLAEVNKQLEDPNVWNDSKNAQALGREKKSLESVVTTLTALDNDLRDAQDLFELAHEEGDEETLVATESDAAKLEARVADIEFRRMFSNPADPNNCFIDIQAGAGGTEACDWASMLLRQYLRYCERKGFKAEVLEESDGDVAGIKNATIKVSGEYAYGYLRTETGIHRLVRKSPFDSSGGRHTSFSSVFVYPEIDDSIEVEINPADLRIDTYRASGAGGQHINKTDSAVRITHMPTGIVVQCQNDRSQHRNRAEAMAMLKSRLFEAELRKRQAEQDKLESSKTDVGWGHQIRSYVLDQSRVKDLRTNVEMSNTKAVLDGDLDDFISASLKQGV", "output": "Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA."}]}
+{"id": "function_test_3169", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MENKRPLILVSNDDGIMAKGISELIKFLRPLGEIVVMAPDAPRSGSGCALTVTQPVHYQLLKKDVGLTVYKCSGTPTDCIKLARNQILDRKPDLVVGGINHGDNSATNVHYSGTMGIVIEGCLNGIPSIGFSICDHAPGADFDAAGPYVRRIAAMVLEKGLPPLTCLNVNFPNTQEIKGVRICEQAKGHWSGEWQACPRRDDANFYWLTGEFIDHEPENEKNDHWALANGYVAITPTVVDMTAYHFMDELKSWEL", "output": "Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates."}]}
+{"id": "function_test_3170", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIYKVFYQASNDEVPVREKTDSIFVEAQSEREVRSKLKPYNYNIEFIQQVEGAFLEYEKQSENFKVLEL", "output": "A non-essential component of RNA polymerase (RNAP)."}]}
+{"id": "function_test_3171", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSLNDYPQQVNKRRTFAIISHPDAGKTTITEKVLLYGNAIQTAGSVKGKGSQAHAKSDWMEMEKQRGISITTSVMQFPYNDCLVNLLDTPGHEDFSEDTYRTLTAVDSCLMVIDAAKGVEERTIKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVESVLKIHCAPITWPIGCGKLFKGVYHLYKDETYLYQTGQGSTIQEVKIVKGLNNPELDNAVGDDLAQQLRDELELVKGASNEFDHELFIGGELTPVFFGTALGNFGVDHFLDGLTEWAPKPQPRQADTRIVESSEEKLTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLKHVRIGKDVVISDALTFMAGDRAHAEEAYAGDIIGLHNHGTIQIGDTFTQGEDLKFTGIPNFAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPMMNNDLIVGAVGVLQFDVVVSRLKTEYNVEAIYENVNVATARWVECADSKKFEEFKRKNEQNLALDGGDNLTYIAPTMVNLNLAQERYPDVTFFKTREH", "output": "Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP."}]}
+{"id": "function_test_3172", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAKAPIRARKRVRKTVSDGVAHIHASFNNTIVTITDRQGNALGWATAGGSGFRGSRKSTPFAAQVAAERCAEAVKEYGIKNLEVMVKGPGPGRESTIRALNAAGFRITNITDVTPIPHNGCRPPKKRRV", "output": "Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome."}]}
+{"id": "function_test_3173", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSELITGQYLSEFINRFQLQLPQPDNVLTHSHYFSATNRRAAVLIPIICRPEPTLLLTRRADHLRKHAGQVAFPGGKADPDDQSLISTALREAEEEVAIPASVVHVLGKLAPLNSSSGYHVTPIVGLVPANIPFYGNDEEVAGLFEIPLHEALSLSRYHSLDIHREGINHRVYLSWYENQFIWGLTATIIRHLAQQVSI", "output": "Probably mediates the hydrolysis of some nucleoside diphosphate derivatives."}]}
+{"id": "function_test_3174", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAKAKFQRTKPHVNIGTLGHVDHGKTTLTAAISKVLADKYPSATNVQRDFASIDSAPEERQRGITINISHVEYETPKRHYAHVDAPGHADYIKNMITGAAQMDGAILVVAATDGPMAQTREHVLLAKQVGVPYLLVALNKSDMVDDEEILELVELEVRELLSSQDYLGDDAPVVRVSGLKALEGDEKWVQSVLDLMEAVDNNIPDPVRDKDKPFLMPVEDVFTITGRGTVVTGRAERGTLAVNSEVEIVGIRPTQKTTVTGIEMFHKQLDEAWAGENCGLLLRGTKREDVERGQVVVKPGSVTPHTSFEGTAYILSKDEGGRNNPIYTNYRPQFYFRTTDVTGVISLTEGTEMVMPGDTTDMTVELIQPIAMEEGLGFAIREGGRTVGAGKVTKIIN", "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."}]}
+{"id": "function_test_3175", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGVASSKILENLMEGTNFDKEEIERLRKRFMKLDKDGSGTIDKNEFLTIPGISSNPLAARLMDVFDEDGNGTIDFQEFIMGLSAFSGKTSKLDKLKFAFKIYDIDRDGYIGNGELFIVMKMMVGKNLQDEELQQIVDKTMMEADEDGDGRLNFHEFKNAVDSKSVASALTLNMI", "output": "Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity (By similarity)."}]}
+{"id": "function_test_3176", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MATFISELEAAKKSLSEALGENVKQYWANLKLWFKQKISKEEFDIEARRLLTQENVHSHNDFLLAILTRCQILISAPEGTGSLNSATKPGKPKGKKKISSVRQKFDHRFQAQNPLAGAQQFVSRDPQEDDELKLCSHTMSLPTRGQLEGRMIVTAFEHGLDNVTEEAVTIVTCALEKHLKDLLTSVVSRRKAYRLKDGHFRYAFGCNVNPQPYLRNSVAAYNQLIECPPVFSSPTGAPNSGSYIHPDDAEQQAALLLACSGDNLTASLPPVNMYDLLEGLQVHREAIPSHTVYALNMERILMKLWHPNTEELQQDEIHRQRLAAKDGLLLC", "output": "Probably involved in transcriptional regulation."}]}
+{"id": "function_test_3177", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MELKNKVSNLPSKPGCYLYLNKDKHVIYVGKAKNLKKRVSSYFDRAQNLKTTRLVREIADLEYFVVSNEKESLLLEENLIKKYRPKYNVLLNDDKAYPYIIITNEKDPTYKYVRKLDKKAFRSFGPLPIGSNARETLITLQRLFPLRRCKGNLGKPCLHYFIGQCSGACFKEVNKEYYQEQIKRVDNFFKGNINEVKTLLTNQMHKAAENLQFEEAQRIKEQIISLDFTTTKQNVEFKSQTDVDVISYFIEDEKIAIVTLFYRSGKLLFKDEHIQLYFEQDITDLIDSFMSQIYDKNILPDKIIVDNEVELFDLNEKYKSISTHPIKEDEKIIYKLATENAQEAIRKSKISTTINIGNENELLLELQEKANLQKEPYRLEMFDISNIGNEFIVGSCVVYINGKPARNEFRKYNIESKFTSDYDRLKEMLYRRFQKALIEKRMLPDLIIMDGGIIQIHAAKEIINALGLSEIQVIGLVKDEHHNTSFLIDTNEEQVIIKDKPKLFNWLSSIQVRVDEYAKSGFRKKQNNSFLKSDLEQIEGLGKKRIQDLFKKFNTINEIESADQEELFKILKNKKALDNLNIYLKNRK", "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision."}]}
+{"id": "function_test_3178", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDFDTNEDLNGVRFAWNVFPSSKTDAMQNVVPLGCMYTPLKEIEGLNVVDYNPVVCAGPHCKAILNPYCMIDPRSNSWTCSICKSRNHLPTQYHNLSQENIPIELQQTTVEYLTTKPVQVPPIFLFVVDITTEPDNLQALKESITASLSLLPANALIGLITYGKVVQLHDFSNDTIARCNVFKGDKDYQLEPLVEMLTGQKMTGSIPNTQVTPFSLNRFFLPLEQIEFRFIQVLESLSQDEWSVKPGERPLRATGSALNIASLLLQGCYKNNAARIIVFSSGPDTINPGLIVDLELKNPIRSHHDIDSGNAVHYKKAMKYYNTLADRISENGHTVDLFSGCYDQIGMSEMRKLTDRTGGVLLLTDSFSTAIFKQSYLRLFAKDEDDYMKMSFSAKFQVKSSKELKVQGLIGHASAVKKTSATNISDTTIGIGGTSTWTMGSLLPQHTYAVFFDIASNGPTPVTGDNQQLAYIQFITNYQHSSGTIRTRVTTVANQLQSFGSPLIAASFDQEAAAVLISRIAVHKAETEEGPDVIKWIDRTLIKLCQKYADYNKNDPSSFRLAGNFSLFPQFMYYLRRSQFLSVFNNSPDETAFYRHIFTREDTTNSLIMIQPTLTSFSMESEPEPVLLDSLSVKADTILLLDTFFYILIYHGETIAQWRKAGYQDDPQYADFKELLEEPKLEAAELLVDRFPLPRFIDTEAGGSQARFLLSKLNPSDSYQNMNSAGATIVLTDDISLQNFMLHLQQSVVNTQK", "output": "Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity)."}]}
+{"id": "function_test_3179", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSKHIAGPEIERLIQLLARIPGLGPRSARRAALHLIKKKETLLEPLGAAIQAAVQKVCICSVCGNVDTIDPCSICTDPRRDDATIIVVEDIADLWALERAKTLAARYHVLGGKLSPLDGIGPDELNIAPLIQRVVQNPITEIILAVNATVEGQTTAHYITDQLSNFSVKVTRLAHGVPVGGELDYLDDGTLAAALQARTNL", "output": "May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO."}]}
+{"id": "function_test_3180", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFFFGDASTRPQIKFLCLFIYFIYMEEIFEKSQLENEQPTSKEPEPALKPVDVMSIKNAAQYVNQKLSAKGYFSNKPNKLRQLLLLSLDSSQLIPENAENFEISEKVYENDRNVMNIIYSLLNSAEISKQFKETALKKMADKDAEIELLKNEVEKLNKKVDEKERNIQSLQLDKIKSDLQAKHYQAMLNNVNAKNKEQERTFRLYAEEVKRELRRNEMEVDRLESRLSNMNKRRASPRDDAEAEPKRQKFDNDRFLSLVKENSHLQHDLNKLVGVLLRLQKFLKSFGQLNSNSKVPSTFIPTDSELLAIDHHNFDLQKYDLILFDLLKPLNGDSIDDTFKFKKNNQTDKDQEIASLRNRLSEMEQNYERVLATMEQWKTYRKQK", "output": "Specifically required for selective degradation of peroxisomes via macropexophagy."}]}
+{"id": "function_test_3181", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MHMKLILNLLVLLAPAAVFAAGGGHGDGHIPTSTIMFQAINLTILFAAIIYFTKDAIVSFFAGRKAAYLEAAQKSAFAREQAEKEFVDIKNKLANLDQTREENLRKAQTHAEDLKKQILEEANDVTKRIKNDAELTARLEVQRAQKELRTQLLQDSVEAARIVLTKDLGSSDQQKLQKDFINNVGV", "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "}]}
+{"id": "function_test_3182", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTNLLKKFNEQQMQVLAKEIPEFRPGDDLKVTFKVVDGTSERIQIFEGVCISKRNRGLHSSFAVRKVSHGESIVSQFFVYSPALVSVQVTRKGKVRRAKLYYLCKLFGKAARIKERTTYVKKKSK", "output": "This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site."}]}
+{"id": "function_test_3183", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MCKIYLMAKSFLKDVLLGFSSLCDRTAAPLRLLLAVSGGADSMAMLSAFLELKSDINAEIFVLTVNHNIRPEKETLGDAQFVLDFCNDKCPCILAEIPKNTVFDEAKNRKTGIEDAARFLRYNEFEKAADSLNADYILTAHNKNDNYETVLMRLFQGSEPEALMGISPRRGRFIRPMLNISRSEIEEYLKEKNIPWREDATNLEASYLRNKVRHNLLPVLSICFDGWQSGLDKSLAKIKAQNDFVIASYKTKKEEWVLDKKEDCCRCKFLFFLSLDEALKLKFLQEGLILLKGKRRIPYSVFDDLMKLSDTKKIIFSGGFCIKKEGDEVLLFKAVTEEKTSEVFYSIWIDKPCSFDTPAGNFKALENDDGFFIVHESDKTCGIGPFKPPFCVRSRLFGDEIETSSGSKKSVKKIINEWNIDYENRNILPIIEEGGVVKGIYGAVFGKKNWYVVGDLGVKR", "output": "Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine."}]}
+{"id": "function_test_3184", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNNSNIIIFPEKYPCSISSLLIKDENDVFVLSHQNVLDCLQFQYPYNMYSQNHMLDDIYWTSQELIEDVLKILHLSGISINKYVIYVLVL", "output": "Mediates the regulatory switch from transcription to RNA replication. Acts late in infection by inhibiting viral transcription and up-regulating RNA replication. Inhibition of transcription by protein M2-2 requires phosphorylation of the phosphoprotein."}]}
+{"id": "function_test_3185", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MMTISDIVQIILFCALIFFPLGYLARHSLRRISDTTRLLFAKPRYVKPAGTLRRATKVKADKK", "output": "Required for cellulose biosynthesis."}]}
+{"id": "function_test_3186", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNAIKNNISLQAQNLSYSIGNQKIIDNVSLSVNKGEIVAIIGPNGAGKSTLLRLLTGYIKPEHGQCDLHGTPIEQWPAEQLARTRAVMRQHSSLSFPFSVEEVVAMGRSPHGIHHKQTAIDTVIEQTDCQALRHRDYRQLSGGEQQRVQLARVLAQLWHPTPIECCLFLDEPTSALDLYHQQHTLRLLYRLTREQPMAMCCVLHDLNLAALYADKIFLLHKGKLVAAGTPEEVLNDHTLRKWYQADLGITRHPETQQPQIYLRQ", "output": "Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system."}]}
+{"id": "function_test_3187", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAAAEPAWEAVIGLETHVQLGTDSKIFTAASTAFGDDPNTHIDPVVCGLPGTLPVLNQKVLEYAVKAAMALNLNIAEHSKFDRKQYFYPDLPKNYQISQYDEPIAEEGWIEVEVAEKGKDTYLKKIGIERLHMEEDAGKLVHAGSDRLAGSTHSLVDYNRAGVALAEIVSKPDLRTGREAAEYASEIRRIMRYLGVSDGNMQEGSLRCDVNISVRRGPDAPFGTKVEIKNMNSFSAIQKACEYEIKRQIKAYETGEPIVQETRLWDEGKQLTKSMRSKEGASDYRYFPDPDLGPIEVSVDQREAWRSELPELPAVKRHRYADDLGLSQYDARVLTDERPMADYFEAVVAAGADAKLSANWITGDIAAHVNSNRLSYAELPFRPEQLAEMVQLIDGGKISGKIAKEILPELLEKGGSPKAIVDERGLGMISDPAALQAIVDELLAAHPDEVKAFRGGKNKLQGFFVGQLMKKTGGKADPKLANQILSKKLKG", "output": "Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)."}]}
+{"id": "function_test_3188", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MISAFYAFLDYLKNIKTASPHTLRNYCIDLNSFKSFLEKQGELSPSSPICLLTKERKETELPFSLFTKDSVRLYVLELMQENKAKRTIKRRLSAIKSFSQYCIKNRIIFEDPTETIHGPRLPKELPSPITYEQVEILMATPDLSKYTGFRDRCLLELFYSSGLRISEIVAINHWDIDFNSNLIRIRGKGKKERLVPMTPHAAQWLQQYLHHPERAHVEQDPQAFFLNRFGKRLTTRSIDRKFQKYLRQSGLSGSITPHTIRHTIATHWLENGMDLKTIQALLGHSSLETTTIYTHVSMKLKKQTHEESHPHS", "output": "Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids."}]}
+{"id": "function_test_3189", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSATINPVVDNSVFTDCKVADLSLADWGRKEIAIAETEMPGLMALREQYADKKPLAGARIAGSLHMTIQTAVLIETLVALGAEVRWASCNIFSTQDHAAAAIAARNIPVFAYKGESLEEYWDYAHQIFEWASDGSHTANMILDDGGDATLLLILGSKAERDPSVIANPTNEEEQVLFASIRSRLASHPGWYSRNLAAIRGVTEETTTGVHRLYEMEKKGELPFPAINVNDSVTKSKFDNLYGCRESLVDGIKRATDVMIAGKIAVVCGYGDVGKGCAQSLRGLGATVWITEIDPICALQAAMEGYRVVTMDDACDKADIFVTATGNLRVITHDHMLKMKDQSIICNIGHFDSEIDIASVQKYQWENIKPQVDHVIFPTGRRIIVLAQGRLVNLGCATGHPSFVMSSSFTNQVLAQIELWQNGKDYQKKVYVLPKRLDEMVARLHLGKLGVKLTELTDEQAHYLNLDKNGPYKPEMYRY", "output": "May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine."}]}
+{"id": "function_test_3190", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIENRPWLTIFSHTMLILGIAVILFPLYVAFVAATLDKQAVYAAPMTLIPGTHLLENIHNIWVNGVGTNSAPFWRMLLNSFVMAFSITLGKITVSMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASATATFLFRQFFMTLPDELVEAARIDGASPMRFFCDIVFPLSKTNLAALFVITFIYGWNQYLWPLLIITDVDLGTTVAGIKGMIATGEGTTEWNSVMAAMLLTLIPPVVIVLVMQRAFVRGLVDSEK", "output": "Part of the ABC transporter complex UgpBAEC involved in sn-glycerol-3-phosphate (G3P) import. Probably responsible for the translocation of the substrate across the membrane."}]}
+{"id": "function_test_3191", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSDKQFIETQGQRLYEALRSARTLAPLTDNHPEMTVEDAYHISLHMLRLREASGERVIGKKIGVTSKPVQDMLNVHQPDFGFLTDSMEYEDGAAVSLKAAGLIQPRAEGEIAFMLKKDLQGPGVTREDVLAATEWVAPCFEIVDSRINDWKIKIQDTVADNASCGVFVIGKQHTDPASLDLAAAAMQMSKNGQPAGSGLGSAVQGHPAEAVAWLANTLGAFGIPFKAGEVILSGSLAPLVPAAAGDRFDMVIEGMGTCSIQFTE", "output": "Involved in the catatabolism of testosterone. Catalyzes the hydration of 2-hydroxyhexa-2,4-dienoic acid to 4-hydroxy-2-oxohexanoic acid."}]}
+{"id": "function_test_3192", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSGPNPNKQPVELNRTSLYWGLLCIFVLAILFSSYFFN", "output": "One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization."}]}
+{"id": "function_test_3193", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVTPQHAQELSTGARELGIDLSEAQHEQLLAYLALLIKWNKAYNLTAVRNPDEMVSRHLLDSLSVVPFIEGTRWMDVGSGGGMPGIPMAILFPERNISLLDSNGKKTRFQTQVKLELKLDNLEVIHSRAENYQPDVPFDGIISRAFSSLEDFAGWTRHMGDVNTRWLAMKGLHPADELVALPSDFHLDSAQALTVPGCQGQRHLLILRRTA", "output": "Specifically methylates the N7 position of guanine in position 527 of 16S rRNA."}]}
+{"id": "function_test_3194", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKASLLNKLDVLSDRFEELTALLGDAEVISDQTRFRAYSREYAEVEPVVALYKQLARVQGDLEGAQALLKDSDPDMREMAVEEVRETKQQLVELEAQLQRMLLPKDPNDGRNVFLEIRAGTGGDEAAIFSGDLFRMYSRYAERRGWRVEILSENEGEHGGYKEVIARVEGDSVYGKLKFESGAHRVQRVPKTESQGRIHTSACTVAVLPEPDEQQAIEINPADLRVDTYRSSGAGGQHVNKTDSAIRITHLPSGIVVECQEERSQHKNRARAMSWLSAKLNDQQTSAAASAIASERKLLVGSGDRSERIRTYNFPQGRVTDHRVNLTLYSLDEVLAGGVDAVIEPLLAEYQADQLAALGE", "output": "Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA."}]}
+{"id": "function_test_3195", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MFKKRVFSWFGFKKNKTKINDLDDHIKKNNQDNLSQKKCNNICSQDSIAKSTKSDCCSENVANSSAVNESHSSSLMKLKLKQHVSHVNNKNSFLLTLTTKLVRTKEAFSIKLKNLFFKKKTYNSLLDDIEEQLLVSDIGVRTTRELVDSLIKVSTQHELKNLNLIIEILKSKMKKILNKVEGPLNINYKNLFVILVVGVNGVGKTTLIGKLAKNYKKKGKSVILAAGDTFRAAAIDQLKLWGEINSVSVITREIGSDPASVVYDAIKIAKLKCIDILIIDTAGRLHNKNNLMEELKKIKRVIHKIDSTISQETMLVLDACIGQNSIKQVKIFHESLNVTGLVITKLDSTAKGGVIFSIAQEFLIPVRYISFGEDFEDIQVFNSNIFVNAILSNNTLK", "output": "Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components."}]}
+{"id": "function_test_3196", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MALKVELKPHERIIVGNSVITNTDQRARLLIDGENVPILRERDILTPETANTPAKLVYLAVQLMYISPDPQTQHGTYFNLVRDIVTAVPSSWPIIEAINNNILNGDLYRALKDARKLIAYEEKLRGQYEATHPKAEADKDDVSTAA", "output": "Has a post-transcriptional repressor function in flagellum biogenesis. Associates with the 5'-UTR of fljK mRNA and promotes its degradation."}]}
+{"id": "function_test_3197", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEFSAKQIAAFIQGEIIGDENATVHTFAKIEEGMPGAISFLSNPKYTPYIYETQSSIVLVNKDFVPEHEIRATLIKVDNAYESLAKLLNLYEMSKPKKQGIDSLAYIAPSAKIGENVYIGAFAYIGENAVIGDNTQIYPHTFVGDGVKIGNGCLLYSNVNVYHDCRIGNECILHSGAVIGADGFGFAPTPNGYDKIPQIGIVILEDKVDIGANTCVDRATMGATIIHSGAKIDNLVQIAHNDEIGSHTVMAAQVGIAGSAKIGEWCMFGGQVGIAGHITIGDRVNLGAQSGIPSSIKADSVLIGTPPMEPKAYFKAAVVTKNLPDMQKEIRNLRKEVEELKQLLNK", "output": "Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell."}]}
+{"id": "function_test_3198", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLNLFILLLERVGLIILLAYILMNINHFKTMMSERDKWRSKFQLIIIFGIFSMISNFTGIEIENGHIVSSDIYYHLSKDASMANTRVLTIGVSGLIGGPWVAIIVGIISGLCRLYIGGADAYTYLISSIVIAIISGYFGHQTIKQNTYPSIKKGAIIGAITEIIQMGCILLFTNNLHHAITLVSFIALPMIIINSLGTAIFLTIILSTIKQEEQMRAVQTHDVLQLANETLPYFRSGLNEKSAQQAAEIILKLMQVSAVAITNKKDILTHIGAGSDHHVARKEIITDLSKEVIQSGKLKVAHTREGIGCHHPNCPLEGAIVVPLYIHNEVAGTLKFYFTDNNIISTSDQQLAKGLANIFSSQLELGQAEMQGQLLKDAEIKSLQAQVNPHFFFNAINTISALVRIDSEKARRLLIQLSQFFRSNLNGARNNTITLQKELQQVAAYLSLEQARYPNRFNIHYRIDDQCQDALIPPFIIQILVENSIKHAFKNRKKNNHIDVDVSMKQDCLSISVQDNGQGIPADQLDTIGYTTVTSTTGTGNALVNLNKRLTGLFGTTSALNIQSSQSGTTVSCLIPYKSSKEEHFNESVNR", "output": "Member of the two-component regulatory system LytR/LytS that probably regulates genes involved in cell wall metabolism."}]}
+{"id": "function_test_3199", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTRIAGVNIPEKKHIVIALKKIYGIGNVLARKICKKTGINFSKKVNSLDSSEIELIRNEVLKLKIEGDLRREMTLNIKRLIDLGTYRGLRHKKHLPVRGQRTKTNARTRKGPRKPIKK", "output": "Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites."}]}
+{"id": "function_test_3200", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNYIPMTLKGAEKLREELKYLKQTKRSEIIKSISEARQYGDLKENAEYQAAKEQQYFCESRIKEIESKLMHSKIIDIKKIPFRDRVVFGSTITIKNLKTLEEKTYKIVGDDEANFKNNLISISSPLSRGLIGKKTLEIVNINTPSGIIKYKILKINYL", "output": "Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides."}]}
+{"id": "function_test_3201", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKPSERRKARRLAVQAIYSWQLSGNNIADVEHEFLTEQSLDGVDVAYFRELFAGVATKKTQLDELIIPHLDRPIDEVSPVEKAIVRLAAYELTFRKDVPFKVAINEAIELAKAFGADESHKFVNGLLDKLVARK", "output": "Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons."}]}
+{"id": "function_test_3202", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MENMAFNQRTVVMIGPGEHYVTAKNEVIKTLLGSCVAVCLYDPKAQVIGMNHFLLAADRRKFTHFLDSRAGYYGVHAMEILINAMLKRGAQRKYLQSKIFGGANVLSLCADNILNHYDIGGMNIDFVRHFLQRERIPIISEDIGGHCGRVIYFDPTDYSVYRSLIEHKYEEIASLQDEEYRYFNQASEDIHSSGVPVVIWSD", "output": "Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis."}]}
+{"id": "function_test_3203", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNVTSLSFPYGESIQWFCADNTKNLPASPLKEWLLAPGSLTQKLKGCCNEFEVRILGEGQCPPLDGEYPNQSAVWVREVLLCLDDVPWVFARTLIPQSLLSTRQADFLGLGTRPLGELLFSQDSFVPGRIEIARFATNSRLAHLAQSLAQNVEHELWGRRRYFHHNEEEMFVSEMFLPAAEQAIARLCP", "output": "Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway."}]}
+{"id": "function_test_3204", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKKLTIGLIGNPNSGKTTLFNQLTGSRQRVGNWAGVTVERKEGQFSTTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHYILSGDADLLINVVDASNLERNLYLTLQLLELGIPCIVALNMLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALKLAIDRYKANENVELVHYAQPLLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAYAGEASQHLDAALARLRNEMDDPALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDKIVLNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDVGSVALFVHGIQWIGYTLHFPDWLTIFLAQGLGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGKSFVPLIVGFGCNVPSVMGARTLDAPRERLMTIMMAPFMSCGARLAIFAVFAAAFFGQNGALAVFSLYMLGIVMAVLTGLMLKYTIMRGEATPFVMELPVYHVPHVKSLIIQTWQRLKGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVDNINDSALASVSRVITPVFKPIGVHEDNWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDEEFNPAEFNLGEELFSAVDETWQSLKDTFSLSVLMNPIEASKGDGEMGTGAMGVMDQKFGSAAAAYSYLIFVLLYVPCISVMGAIARESSRGWMGFSILWGLNIAYSLATLFYQVASYSQHPTYSLVCILAVILFNIVVIGLLRRARSRVDVELLATRKSVSSCCAASTTGDCH", "output": "Probable transporter of a GTP-driven Fe(2+) uptake system."}]}
+{"id": "function_test_3205", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAKAKFERTKPHVNIGTIGHVDHGKTTTTAAITKVLADAYPELNEAFAFDAIDKAPEEKERGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKCDMVDDEEIIELVEMEVRELLAEQDYDEDAPIVHISALKALEGDEKWAGQILELMQACDDNIPDPVRETDKPFLMPIEDIFTITGRGTVVTGRVERGTLNVNDDVEIIGIKEKATQTTVTGIEMFRKLLDSAEAGDNCGLLLRGIKREDVERGQVVVKPGAYTPHTEFEGSVYVLSKDEGGRHTPFFDNYRPQFYFRTTDVTGVVKLPEGVEMVMPGDNVDMSVTLIQPVAMDEGLRFAIREGSRTVGAGRVTKIIK", "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."}]}
+{"id": "function_test_3206", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSKTLSFKTYSAKPGEVKRTWHIIDAENQVLGRMAAQIANVLRGKHKPQFTPHIDTGDFVVVTNAAKVALSGKKRDDKTYFSHSHYPGGVRIDSVKDLLQKKPEKVIEHAVWGMLPHNNLGRQLFKKLKVYAGPEHPHAAQMPVEMKINQ", "output": "This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly."}]}
+{"id": "function_test_3207", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAKKITGFIKLQIPAGGANPAPPVGPALGQKGVNIMEFCKQFNAKTQSEAGMIIPVVITVYSDKSFTFVTKTPPAAVLLLKEAKLQKGSGEPNRNKVGTVTMDQVRKIAELKRPDLNSIDLEGATQMVIGTARSMGIVVEG", "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors."}]}
+{"id": "function_test_3208", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MATSKILLYYAFTPLSDPKAVQLWQRELCESLNLRGRILISTHGINGTVGGDIDDCKAYIKKTREYPGFNRMQFKWSEGGAEDFPKLSVKVRDEIVAFGAPDELKVDENGVVGGGVHLKPQQVNELVEARGDEVVFFDGRNAMEAQIGKFKDAVVPDVETTHDFIAEIESGKYDDLKDKPVVTYCTGGIRCEILSSLMINRGFKEVYQIDGGIVRYGEQFGNKGLWEGSLYVFDKRMHMEFGEDYKEVGHCIHCDTPTNKFEHCLNEDDCRELVLMCPDCFANVETRHCKRERCAAIAADFAEQGIDPLVTS", "output": "Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs."}]}
+{"id": "function_test_3209", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSSSGLQLHIAGKRFGTRQVLRDIDLQLAPGEIVSLIGASGCGKSTLLRILAGLERDYAGEVALDGARVRGVDRQIGFIFQEPRLLPWLDVAANVAFADEADLSPAAARQSARVQQLLAQVGLLDYATALPKQLSGGQAQRVALARGLYRQPRVLLLDEPFSAVDAFTRIKLQDLLLRLAGEHGFSVLLVTHDIDEAVYLSDRVIVIGGQPGTIAHAQRLELPRPRDRQAHEAALRQARQDLLAALHSLHVF", "output": "Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system."}]}
+{"id": "function_test_3210", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLDMTERQVESVLIEIPKGSRNKYEYDKEKKVIKFDRMLFSSMVYPCDYGFFPDTLALDGDPLDALVLTWEPTFPGCVIDVHPVALLDMKDDKGRDEKILCVPETDPLWNYIETLEQVPPHLLKEIVHFFETYKNLEGKHVIVIGWEGLDAAVDMLREAKSRYLEKNK", "output": "Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions."}]}
+{"id": "function_test_3211", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSLIEIDGSYGEGGGQILRTAVGMSALTGEPVRIYNIRANRPRPGLSHQHLHAVKAVAEICDAECEGLEIGSTEIVFEPGKVKGGEYEVDIGTAGSVTLLLQAVKLAAIAADGPVEMEVRGGTDVKWSPPVDYEINVNAHYLDRLGYRYELEVLRRGHYPRGGGIVRARMEPPKRLKPLEAVKFGELESVRGISHCVRLPPHVAERQAKAASEIIERELGIRPEIEIETYPKGRDPHLGPGSGIVLWAEDDQGNRIGADALGEKGKPAEVVGREAAEQLVQRLRTGMALDEHMGDQILPFLAIADGESVFGVTGVDPHLPTNAWVVEKFLPVSVEIRGKEGEPATVEVRPEG", "output": "Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing."}]}
+{"id": "function_test_3212", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEIDYYDYEKLLEKAYQELPENVKHHKSRFEVPGALVTIEGNKTIIENFKDIADALNRDPQHLLKFLLREIATAGTLEGRRVVLQGRFTPYLIANKLKKYIKEYVICPVCGSPDTKIIKRDRFHFLKCEACGAETPIQHL", "output": "eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA."}]}
+{"id": "function_test_3213", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MITIALPSKGRMKEDASAVLERAGLKVASVGNDRSYRGRIEGRDDIEVAYLSASEIAREIGAGTVDFGVTGEDLVREGLTNADAQVEFCARLGFGHADVVVAVPEIWLDVDSMADLGDVASEFRARHGRRLAIATKYWRLTQQFFSRQHGIQLYRIVESLGATEGAPAAGQADIIVDITSTGSTLKANHLKILSDGIIVRSEACFVRARKPEHEGDAAIQEIASRIKAAV", "output": "Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity."}]}
+{"id": "function_test_3214", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAKPVVAIVGRPNVGKSTIFNRIVGERVSIVEDVPGVTRDRIYNSAEWLGKEFNIIDTGGIDLSDEPFLEQIRAQAEIAIDEADVIIFITNGREGVTDADEQVAKILYRSNKPIVLAINKVDNPEMRDQIYDFYSLGFGEPYPISGSHGLGLGDMLDAVRAHFPKEEEEEYPDDTVKFSLIGRPNVGKSSILNALLGEDRVIVSDIAGTTRDAIDTTYTFDGQDYVMIDTAGMRKRGKVYESTEKYSVLRAMRAIERSDVVLVVINAEEGIREQDKRIAGYAHDAGRAIIIVVNKWDAINKDEKTINVWTEDIREQFQFLSYAPIVFVSAKTKQRLNNLFPLINQVSDNHSLRVQSSMLNDVISDAVAMNPSPMDKGKRLKIFYTTQVAVKPPTFVVFVNDPELMHFSYERFLENRIREAFPFEGTPIRVIARKRK", "output": "GTPase that plays an essential role in the late steps of ribosome biogenesis."}]}
+{"id": "function_test_3215", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MISYYFQGFALGAAMILPLGPQNAFVMNQGIRRQYHLMIALLCALSDLVLISAGIFGGSALLMQSPWLLALVTWGGVAFLLWYGFGALKTAMSSNLELASAEVMKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLAMEPKRWFALGTISASFLWFFGLALLAAWLAPRLRTAKAQRIINILVGVVMWLIAFQLAREGVAHMHALFN", "output": "Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine."}]}
+{"id": "function_test_3216", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTKQIITLVGRPNVGKSTLFNRLSIRKKAIVHDLPGVTRDRKYTDGKIGSFEFLLIDTPGLDENPNSMGERLIEQTTKAILEADLICFMVDGRSGILPDDKLLSSFVRKYNKPAILVVNKCEKAFDFDKEYYKLGFDSMIAISAEHGTGLIDLYDEIIAKLPEEESIKTNIADPIKGDCLQIVVSGRPNAGKSTFINALINDERLLTGPEAGITRESIEIDWQYKNNHIKLIDTAGLRKKSTITESLEKLSASDTINSIKFANTVILMIDALAPLKQQDLNIASHVVHEGRSIVIVVNKWDLVKESEKEAFQEEFYYQINTHLPQVKGIPVLFISAINKQNIEQVLDACLKIYKIWNKKITTSKLNEWLNFTTEAHLLPLQKGGRRVRVKYMTQTKTRPPTFKLFSNNPEKITDSYTRYLVNNMREAFDMPGVPIRFIYVKTKNPYV", "output": "GTPase that plays an essential role in the late steps of ribosome biogenesis."}]}
+{"id": "function_test_3217", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTIRFDNVSYTYQKGTPYQHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDKYIRPVRKRIGMVFQFPESQLFEDTVEREMIFGPKNFKMNLDEAKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVVDEPTAGLDPQSKRQVMRLLKSLQTDENKAIILISHDMNEVARYADEVIVMKEGSIVSQTSPKELFKDKKKLADWHIGLPEIVQLQYDFEQKYQTKLKDIALTEEAFVSLYKEWQHEK", "output": "ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates."}]}
+{"id": "function_test_3218", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLPARPEPLPVDPKTTAVIVIDMQNAYASPGGYLDLAGFDISGAAKVTHEIKGVLEVARSAGMTVIYFQNGWDDGYVEAGGPGSPNWWKSNALKTMRARPELQGKLLARGQWDYELVDDLTPQPGDIRLHKTRYSGFFNSQLDSVLRARGIRHLVFTGIATNVCVESTLRDGFMLEYFGTVLEDATHQAGPDFVQKAALFNIETFFGWVSTTADFKGTFGQLAPG", "output": "Hydrolyzes ureidoacrylate to form aminoacrylate and carbamate. The carbamate hydrolyzes spontaneously, thereby releasing one of the nitrogen atoms of the pyrimidine ring as ammonia and one of its carbon atoms as CO2."}]}
+{"id": "function_test_3219", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGKLTLGHRGEASEPDFFRGVLGELVLTFLFVFIGVGAAMTDGATTKGSTAGGDLTAVALGQALVVAVIATAGFHISGGHVNPAVTLSLAVGGHVTLFRSSLYIAAQMLASSAACFLLRWLTGGLATPVHALAEGVGPLQGVVAEAVFTFSLLFVIYATILDPRKLLPGAGPLLTGLLVGANSVAGAALSGASMNPARSFGPAVASGVWTHHWVYWVGPLAGGPLAVLVYECCFMAAAPTHDLLPQQDP", "output": "Aquaporins facilitate the transport of water and small neutral solutes across cell membranes."}]}
+{"id": "function_test_3220", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPTDDPSDRPSGLLDQLSRLIETLAELDDDNGEQHGHSTIDRGRTRIDYDYAVSIGLGSDARSPSTPAGNADDAGDAETAHIETRASDDSDDLVVVADLPGVTDETAVDAAVEDTGALTISVGDDVVERLTLDDPGMTITSLTVTNQILELRVTPSEPSATDT", "output": "May play a structural or regulatory role in gas vesicle synthesis."}]}
+{"id": "function_test_3221", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAEENIIFVGKKPTMNYVLAVVTQFNNNANKIIIKARGKTISKAVDVAEITRHKFIPDAKYEEIKLDTETLQGERGSSNVSSIEITLSR", "output": "Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes."}]}
+{"id": "function_test_3222", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTTSSGSRIGGLLHASLFSLLGLGLLLAGGFKTVERYHFLRTAQEAQGTVSALNAGGSHPQIDFTSVSGERISYPQGGFIFGYQVGEPVRVLYEAGRPAASAIVDDAGALWGTGAFLCGFGALFGIVGFRGLLGLRSSQPTSKGH", "output": "Immunity protein that plays a role in preventing early activation of toxin Tse4."}]}
+{"id": "function_test_3223", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAPGDKKQIIFVITTIGRPSSTVVPFKNLEVSEWSYKKGIKNGYDDYRDPPSPKPLPKSKQEPNADDKVGDIEYDEMVSVRDGYYSDVCRLTCTEDTKIFIADHISLWRYIMDNAEKLPNYVVIMEDDNTITGEGFITNLDNITKVLNDNNVDILQLVTHTKLLKDRNSQHLMLLPDLEAFKGSFDVSLSAYIIRQEAVRKLYSYFTNNKPSFDISLEILRIENTLGITRYVVDNDRYVYHDYKLANEFMKNKKNRLSIKSRIDGWIMDNWPSFYHRMYYPLFSVFGKYDITMMFLIAIVIIIGLAIFDINNKLLWLLSGVFLAYSM", "output": "Envelope protein that binds to the cell surface to provide virion attachment to target cell."}]}
+{"id": "function_test_3224", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTLAEFWPLCLRRLHDMLPQGQFAQWIAPLTVGEEGGVWVVYGKNQFACNMLKSQFAGKIEAVREELAAGRSAFVFKPGEGVRYEMAAVEGAVEPAEPSLHAVSEGMPVQEVLLDELPSEEPVKPAASKTAADILAERMKNLPHEPRQAAGSASRPESVAVAKARTDVQRDAEEARYEQTNLSPDYTFDTLVEGKGNRLAAAAAQAIAESPGQSYNPFFLYGSTGLGKTHLVQAVGNELLKNRPDAKVRYMHSDDYIRSFMKAVRNNTYDVFKQQYKQYDLLIIDDIQFIKGKDRTMEEFFYLYNHFHNEKKQLILTCDVLPAKIEGMDDRLKSRFSWGLTLELEPPELEMRIAILQKKAEAAGISIEDEAALFIANLIRSNVRELEGAFNRVGASSRFMNRPVIDIDLARTALQDIIAEKHKVITADIIIDAVAKYYRIKISDVLGKKRTRNIARPRQVAMSLTKELTTLSLPSIGDSFGGRDHTTVMHGIRAVAKLREEDPELAQDYEKLLILIQN", "output": "Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)."}]}
+{"id": "function_test_3225", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRCPACHHNGTRVLDSRPAHEGRSIRRRRECESCNHRFTTFEMIEEVPLIVVKKDGTRQEFSSDKILRGLIRACEKRPVPLETLEGIVNEVERELRGQGKNEVDSKEIGELVMERLANVDDVAYVRFASVYRQFKDINVFIQELKELMERDDR", "output": "Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes."}]}
+{"id": "function_test_3226", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIAFVSGTVAALAPDAAVIEVGGVGMAVQCTPNTLSTLRLGKPAKLATSLVVREDSLTLYGFADDDERQVFELLQTASGVGPRLAQAMLAVHQPDALRRAVATGDEKALTAVPGIGKKGAQKLLLELKDRLGEPIGAPAVGAPVSTGWRDQLHAALIGLGYATREADEAVSAVAPQAEAAGGTPQVGALLKAALQTLNRAR", "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."}]}
+{"id": "function_test_3227", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MMDSSPEKTNLELLYEQVCEQGREFEVVFYPMLPRLYEMMLPSLEARLNFLSVGYRHVAFSRYVHGDVDCVHREVMAQKMVLLTSILSKLLNVNGILEHQEYLNTE", "output": "Component of the molecular motor that translocates viral genomic DNA in empty capsid during DNA packaging. Forms a tripartite terminase complex together with TRM1 and TRM3 in the host cytoplasm. Once the complex reaches the host nucleus, it interacts with the capsid portal vertex. This portal forms a ring in which genomic DNA is translocated into the capsid."}]}
+{"id": "function_test_3228", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "ANNAGARKAIRKIEARTEVN", "output": "Binds directly to 16S ribosomal RNA."}]}
+{"id": "function_test_3229", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MVRVKRGNVARKRRKKILKLASGFKGAHSKLFRVANQQVNKSLRYSYVGRKLKKRRFRRLWILRLNAASREEGLNYSKLVNSLKLLRIQLNRKSLSQLAMIDNDAFKRLVASSRV", "output": "Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)."}]}
+{"id": "function_test_3230", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTEEISKDTIIEVAIDDIRVSPFQPRRVFSNEELQELIASIKAVGLIHPPVVREICTGDRVLYYELIAGERRWRAMQLAGATTIPVILKHVIADGTAAEATLIENIQRVNLNPIEMAEAFKRLIHVFGLTQDKVAYKVGKKRSTVANYLRLLALSKTIQESLLQGQITLGHAKVILTLEDPILREKLNEIIIQEHLAVREAELIAKQLISEEGSSIELKPTPLDMAESSKQHEELQQRLSDLCGYKVQIKTRGSKATVSFHLQNTQDLQKLEAWLSSHGTLSESLS", "output": "Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication (By similarity)."}]}
+{"id": "function_test_3231", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRKSKVLTLGFQHVLAMYAGAVIVPLIVGSSLKLNAEQLAYLVSIDLLTCGIATLLQVWRNKFFGIGLPVMLGCTFTAVGPMIAIGSEYGMPAIYGSVLASGLFLALFAGFFGKLARFFPPIVTGSVVTIIGITLIPVAVQDMGGGQGSADFGSLSNLALSFGVLLFIILANRFFTGFIRAISILLGLIFGTIAGAFMGKVDIGPLLDASWFHGIHPFYFGFPTFHLPSILTMTLVAIVSVMESTGVFVALGKITEKELTADDLKRGYRSEGLASILGSIMNSFPYTTYSQNVGLIQISKVKSRDVVITAGFILVILGFMPKIAALTLLIPTAVLGGAMIAMFGMVVSSGIKMLGAIDLNNHENLLIIACSVSVGLGVTVAPNLFDHLPDSIKILTSNGIVAGSLTAILMNFLFTVGRKKQDESHASAENVHAA", "output": "Uptake of the purines adenine and guanine, and the pyrimidine uracil. Transport is probably proton-dependent."}]}
+{"id": "function_test_3232", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKVIFLKDVKGKGKKGETKNVADGYANNFLIKNGYAVEASNAALSTLSAQKKKEDKLAAEELAEAKALKEKMEKLTVELKAKSGEGGRLFGSITSKQIAQTLEKTHGIKIDKRKMDLPEAIRALGHTKVPVKLHHEVTATLDVHVSEE", "output": "Binds to the 23S rRNA."}]}
+{"id": "function_test_3233", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAREIALDHVRNIGIMAHIDAGKTTVTERILYYTGRSHKIGEVHEGAATMDWMEQEQERGITITSAATTCFWKEHRINIIDTPGHVDFTIEVERSLRVLDGAVAVFCGVAGVQPQSETVWRQADRYGVPRLAFVNKMDRMGADFNKAVQTMKDRLKARAIPAQYPIGAEEDLRGMVDLITRKAYIFNDESLGAEFEVLDCPEDIEAEVEEAREALLEAALEQDDTLMEKYLEGEEITIAEFKSCMRRAVISSAFVPVFCGSAFKNKGVQLLLDAVVDYFPSPSDTPYIEGLLPDSEEAAVRKPSDEEPFAALAFKIMTDPFVGTLTFVRVYSGVMESGTSVLNASKDRKERIGRLMLMHANKREDIKEVRAGDICAVVGLKNTTTGETLCDPNKPIILEKMDFPAPVIAIAVEPKTKADQERMGVALQRLAQEDPSFRVEVDHETNQTIISGMGELHLEIIVDRMMREFKVDANVGQPQVAYRETITQMVEHESKFVRQSGGRGQFGHVWLRLEPNEPGAGYEFVDGIKGGVVPKEYIPAVKNGVGEAMANGVYVGFPMVDVKVTLFDGSYHEVDSSEMAFKIAGSMGLKEGAMKAKPVLLEPIMDVEVETPEDYMGDVMGDMNSRRGQIQGMEDSGNNRLVKAQVPLSGMFGYATDLRSMSQGRATFTMQFGHYAQVPKSIAEEIKAKTTG", "output": "Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome."}]}
+{"id": "function_test_3234", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAKAKFQRTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKYPELNESRAFDQIDNAPEERQRGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKSDAVDDEELLELVEMEVRELLAAQEFDEDAPVVRVSALKALEGDPKWVESVEQLMDAVDESIPDPVRETDRPFLMPVEDVFTITGRGTVVTGRVERGIINVNEEVEIVGIRPTSTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGIKREDVERGQVVVKPGTTTPHTEFEGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEGTEMVMPGDNTNISVKLIQPVAMDDGLRFAIREGGRTVGAGRVVKIIK", "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."}]}
+{"id": "function_test_3235", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MHIMVTNDDGIQAPGIQALASALRVLGEVTVVAPDRERSAVGHALTLNSPLRVFELRDGFYAVDGTPTDCVNMGIHSLLPFRPDLIVSGINHGANLGDDVTYSGTVAAAIEATLMGIPAIAVSLATQERSGHFPEAAQIAVRVARQVLSNGLPEDTFLNVNVPDCPAEEIRPPLVTRQGKRSFVGNVIDKTDPRGRKYYWIGSGEADFNDYEGTDFHAINRKHVSITPLHLDLTNYASMKVITTWVF", "output": "Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates."}]}
+{"id": "function_test_3236", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNVRGRVAPRRVTGRAMSTLLAYLALTKPRVIELLLVTAIPAMLLADRGAIHPLLMLNTLVGGMMAATGANTLNCVADADIDKVMKRTARRPLAREAVPTRNALALGLTLTVISFFWLWCATNLLAGVLALVTVAFYVFVYTLWLKRRTSQNVVWGGAAGCMPVMIGWSAITGTIAWPALAMFAIIFFWTPPHTWALAMRYKQDYQVAGVPMLPAVATERQVTKQILIYTWLTVAATLVLALATSWLYGAVALVAGGWFLTMAHQLYAGVRAGEPVRPLRLFLQSNNYLAVVFCALAVDSVIALPTLH", "output": "Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group."}]}
+{"id": "function_test_3237", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLDREGYRPNVGIILTNNRDEVFWGKRVREHSWQFPQGGIKPGESPETAMYRELYEEVGLLSQHVKIVGRTRDWLRYDVPNNWVRREWRGSYRGQKQIWYLLRLTGRDCDVNLRATRHPEFDGWRWHQYWAPVDEVIDFKRDVYLGALKELSSRFLRGMESYEDFAARQLSGNR", "output": "Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage."}]}
+{"id": "function_test_3238", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVRKLGIEEELLLFDPESGEVVPAAPSVLKEFREHGPGRQRARAATDELDQELFRHQLETRTDPVRRAADALDQLVAARRTAGEAARAAGYAAGACGIVPLGGDRSVVSPNDRYRDMVDTYGEIARTGGTCGMHVHVDIGSDEEGVAVVDRIAPWLPVLVALAANSPYVEGRDSGYASWRAQVWARWPSAGPTEQFGSVAGYREVCRMLLDVGAARDPGMLYFDARLSTGQPTVEVRVCDVGTDPAVAVTIGALVRALVETAAEEWADGRPAAHWRAEALRAAHWRASRFGMADSLVHPLARGLRPARSVVAALVEAVEPALAAAGDLELVDVQLERAVNDNGATRQRAAFERTGSVRGVVDDVIARTEASWQDHDSHAGRL", "output": "ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity."}]}
+{"id": "function_test_3239", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRVGCDIIAISRIEKIHSRHGKNFLDKFLSPKEQILIKNPATLAGLWAAKEAASKALGVGICELCSFFDIEISKDEKNAPKLKYSQKITKDFNITQTSLSISHDNGFAIAIVAIV", "output": "Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein."}]}
+{"id": "function_test_3240", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MALTNADRAEIIAKFARAENDTGSPEVQVALLTAQINDLQGHFKAHKHDHHSRRGLIRMVNQRRKLLDYLNGKDHERYTALIGALGLRR", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.; "}]}
+{"id": "function_test_3241", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSGLPIATNLYFDAHFHRHGVKLLPNEFYTTREDMVLVTVLGSCVAACLHDPIGRIGGMNHFMLPDDGADPSAAASESMRYGAYAMEVLINELIKAGGRRERFEAKVFGGAAVLAGMTTINIGDRNADFVRRYLALERIRITAEDLQGVHPRKVAFMPHTGQAMVKKLRVQAPDVAAREAALAREAVDPHGERAPRVRPRVELFGTPAPKAQAKPRIELFGMRATQPATRKQEA", "output": "Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis."}]}
+{"id": "function_test_3242", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEVKAIHRGARISAQKTRLVADQIRGLPVDKALNVLTFSPKKAAGIVKKVVLSAIANAEHNEGADIDELKIKSIYVDKAASLKRFTARAKGRGNRIEKQSCHITVTVGN", "output": "This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).; "}]}
+{"id": "function_test_3243", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDDSKVSGGKVKKPGKRGRKPAKIDLKAKLERSRQSARECRARKKLRYQYLEELVSSRERAICALREELEMYKQWCAAMDQGKIPSEIKALLSGEDLKAAPNQVKHRAVKTEQKEKCP", "output": "Probable regulator of creb1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle (By similarity)."}]}
+{"id": "function_test_3244", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPKRGKKYLEALKLVDRFKAYPVAEAIELVKKTNVAKFDATVEVAFRLGVDPKKADQQIRGAVVLPHGTGKVARVLVFAKGEKAKEAEAAGADYVGDTEYINKIQQGWFDFDVVVATPDMMGEVGKLGRILGPKGLMPNPKTGTVTFDVTKAVQEIKAGKVEYRVDKAGNIHVPIGKVSFDNEKLAENFATIYEAILKAKPAAAKGTYVKNVTITSTMGPGIKVDPTTVAVAQ", "output": "Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.; "}]}
+{"id": "function_test_3245", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MFQKCEAIVIRAIDYGETNKIVTLFTREWGKVAAMARGAKKPSSRLSAVTQPLAYGHYLIRRSRGVGLLHQGELIDSMRVLREDLFAAAYAAYIVELTDKSTEEQKRNPYLFELLLQTLQYMSEGRDLEIMTFIYEMKMLSVLGIPPVLDRCARCGATEGRFSFSVKEAGFLCHRCESADPHRFPLSPASIRLLRLFYHIDLTRLGAISVKEGTKAELRAVLSSYYDEYAGLSLKAKRFLQQIGELKGTLDPGDGRNN", "output": "Involved in DNA repair and RecF pathway recombination."}]}
+{"id": "function_test_3246", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKTLTDSFVYLGHWPSAGSFGFNTDILATNPINLSVVFGVLIFFGKGVLNDLLDNRKQRILNTIRNSEELREGAIQQLENALARLRKVETEADQFRVNGYSEIEREKLNLINSTYKTLKQLENYKNETILFEQQRTINQVRERVFQQALQGAIGTLNSCLSNELHLRTINANIGMFGTMKEITD", "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "}]}
+{"id": "function_test_3247", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MHMNPTPLPHSEDDGVMFASIGQTTLALTEPPSALHATDTLDDVFGSEDVQGSTSFTTEPSDMRRLQSEHTTAGYREGVTVAKAASVQAGFDEGFGLGATLGLSAGEIVGVLEGLAAAVPGDERLAALLGEARGDFSARSIFGATYWDPNGTWTYPVPGQDGGDVIFRDVVEAHPLIAKWRVVLNEQIQNWGVRCDFFAEDQVVDEEVVSQKKLGNPATALKAATSTAPATQSRMSDALQW", "output": "The complex LTO1:YAE1 may function as a target specific adapter that probably recruits apo-RPLI1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery. May be required for biogenesis of the large ribosomal subunit and initiation of translation."}]}
+{"id": "function_test_3248", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MASKKIDRLSFDATLEELETIVHQLEQGSLPLEEALKQFEQGVHLVRAGQQKLEQAEQKIQILLTQADGTEQAVPFQPEQGEE", "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."}]}
+{"id": "function_test_3249", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAKKDGAIEVEGRVVEPLPNAMFRIELENGHKVLAHISGKMRQHYIRILPEDRVVVELSPYDLTRGRIVYRYK", "output": "One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex."}]}
+{"id": "function_test_3250", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPKVGMQPIRRQQLIEATMAAVNEVGMHEASIAQIAKRAGVSNGIISHYFRDKNGLLEATMRYLIRHLGEAVKQHLAALSVNDPRARLRAIAEGNFDDSQINSAAMKTWLAFWASSMHSPQLYRLQQVNNRRLYSNLCAEFKRCLPREQAQLAAKGMAGLIDGLWLRSALSGEHFNRQEALLIIHNYIEQQLNIKYKC", "output": "Repressor involved in the biosynthesis of the osmoprotectant glycine betaine. It represses transcription of the choline transporter BetT and the genes of BetAB involved in the synthesis of glycine betaine (By similarity)."}]}
+{"id": "function_test_3251", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSKQTKTFEENLAELEGIVTKLERGDVALEEALAEFQKGMVLSKDLQKTLAEAEKTLVKVMQADGSEAEMD", "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."}]}
+{"id": "function_test_3252", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNGIVNVLKPPGMSSHDVVDRIRRIFGVKKAGHTGTLDPGAAGVLVVCLGVATRLARFLLGEDKEYRVEITFGMSTSTGDSYGEITDQRDASFLKEHDIIRVLPEFTGEVRQVPPMTSAIKWRGKKLYELAREGLVVERQERAVYIKSLEFIRGSGWGTPSPRALMHLSCSKGTYVRSLCHDMGSRLGCGAHMSFLVRTRAGPFKIADSVTLEELQAAASKGVLERKIIEMDRAVSEYPEVIVKSSAVKAVAAGSKLYIPGVARMPLDLDCGKLVRLTGPDGLLAIAEAGREPFDKEKLFFKPVCVLARQAGRSSN", "output": "Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs."}]}
+{"id": "function_test_3253", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPTVALYNTNGEQVGELALKDEIFGVEVHEPVLHDAVVMHLANRRLGTHDTKTRSEVRGGGRKPWRQKGTGRARHGSIRSPLWRGGGIIFGPHPRDYSYSLPRKVRRLALKSALSAKVNSGDILVLDELKLDQPKTKEMARILNNLKVDDALLVTAEKDEAVERSARNIPNIKPVQAALLNVYDILAYDKLVMTRDAVARVEEVFA", "output": "One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.; "}]}
+{"id": "function_test_3254", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKNLFSLLKLTVFTLILFAVIYPLAIYGIAKLAPNQGKGETISVNGKVVGYQKIGQKFDKSNYFWGRPSAVDYNAAGSAGSNKGPSNADYLALVQKRIDTLLLVHPYLKKSDIPVDMVTASGSGLDPNISPQGALIQVKRIAKERMLDEAKVKSLVESKINTAVVGPETVNVLELNVALDQLK", "output": "Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex."}]}
+{"id": "function_test_3255", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEKFLDINEIKKIIPHRYPFLLVDKITELEEGKSAVGYKNVTANEYFFNGHFPEEPVMPGVLIIEALAQVGAVAILSKEEFKGKIAYFGGINKAKFRKKVVPGDVLKLSIDLTKIKGVAGVGKAVATVDGKVAAEAELLFVIGK", "output": "Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs."}]}
+{"id": "function_test_3256", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKKRLAVLLVIVLTITFSFSVTTRIKDIAFFRGARDNQLFGIGLVVGLNGTGDSGNVNSPLLLEMMKKFGVQVSENDLKSKNTALVMVLADIPPFAKEGMRIDCVVASIADAKSLAGGYLLQTPLYGADGKVYAVAQGSVIIGGEDVKLSSNLQKRYRVVGYLPEGAIVERDIPSDMLDGDSVTILLRQPDITTAARVARAINEKFEMDLAKAIDPSAIKLTVPNAFQDDLITFLSLVEEIEVQPDVPARIVVNERTGTVLFGGDVKLSDFVISYGNFTISVTGGKIGDKDATISNLVSALKAAGATPQDIIAILQVIYESGYITGELIIM", "output": "Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation."}]}
+{"id": "function_test_3257", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAHSQVGIQLISESTEKTLAELTALCAEYNIIHNEKSPLALVQTDERLELRKLDEPKLRAVYVDFIGGTMAHRRKFGGGRGEAVAKAVGIKGSALPTVIDATAGLGRDAFVLAAIGCQVRLVERHPVVFLLLQDGLNRAYQDEEIGEILQQNLRLLNVHHINELDPNSDYADVVYLDPMYPHKQKSALVKKEMRVFQHLVGADLDADELLLPALQLAKKRVVVKRPDYAEFLCGKQPHFSRETKNHRFDIYMGASQC", "output": "Specifically methylates the guanosine in position 1516 of 16S rRNA."}]}
+{"id": "function_test_3258", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MVRKNQEWPDEGELIIGTVYKVLNYGAFAKLEEYHGKEAFIHISEVSSGWVKNIRDHVRENQKIVCRVLRVNPKKGHVDASLKRIREDQRTKKIQHWKIEQKAEKFLELSAKSLGKSLNDAYDEVGYELMDIFGDVYGAFETAADDGAKSLTDEGISQEWADAITEIANKNITPPEVHISGYVDIETFVPDGVDVIIEALKAAEDNGDEEEEIKVQCVGAPRYRITVKSTDYILAEKALKAAADRCIEIVEASEGNGSFLRELDS", "output": "eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA."}]}
+{"id": "function_test_3259", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLKPLGDRVVLKAETEEEKTVGGIVLASNVKEKPTTGKVIAVGEGRTLENGQKLAPAVKEGDRVLFDKYAGNEVEYNGEKFLVVHAKDLVAIVE", "output": "Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel."}]}
+{"id": "function_test_3260", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSKVSNGGGDSKNTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREENKSSMVKSREGVPTPQEIMAVLDDYVIGQKDAKRVLSVAVHNHYKRLAHQSKNSDIELAKSNILLVGPTGCGKTYLAQTLARIIDVPFIMADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLDRIISARGEKTSIGFGATVKSVDERRIGEVFKELEPEDLLKFGLIPEFVGRLPVIATLEDLDVDALVQILTEPKNALVKQYQRLFDMENVELVFHDDALRAIANKAVERKTGARGLRSIMEKILLDTMFELPTLEGVREVVISGDVVDGSARPLYIYAERQDEKGNVSAGMA", "output": "ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP."}]}
+{"id": "function_test_3261", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MASPDKKSSLAALTLAAVGIVYGDIGTSPLYTMKEVFSKEHGLALTPENLLGVVSLIVWGLIIIVSLKYVTLVLRANNRGEGGIMALMALALSSVTRNSRWYFPLLVMGLFGATLFYGDSVITPAISVLSAIEGLSVATETFDPYVVPLTVAVLVGLYSVQARGTAGIGKWFGPIMVVWFATLAVMGVVNIIDAPEILYALNPWHALHFLDGNRFLAFIALGAVVLAFTGAEALYADMGHFGAKPIRMAWFLVAFPALALNYLGQGALLLMHPDAVTNPFYQQLGAWSIYPLVALSTMAAIIASQATISGTFSMTKQAIALGFLPRMKIEFTSASQIGQIYIPAVNWLQMAVVVMAVVGFGSSSDLAAAYGIAVTATMLVTTILTFFVIRYRWKYNLLLCLASTGFFLVIDLSLFSANMLKLFHGGWFPLLLGTILFTLMLTWKRGRELVFENLQKHAIPLEDFLASLFISPPTRVPGTAIFLRGESDGVPHAMLHNLSHNKVLHERVVFLTVRMMEVPYVPTTDQVRIHLLGDDCYQMDVTYGFKNVPDIPAALELAKDQGLEFEMMETSFFIARQTVVANPVRGMALWREHIFVAMSRHARGAADYYQIPSNRVIELGTKVEI", "output": "Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter."}]}
+{"id": "function_test_3262", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPRKGNVPKREVLADPIHGSMVVAKLINSVMLDGKKGTAQNIVYGAFDIIKERAEENPVEVFEKAMNNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLRWLVKYTRARGEKGMIEKLAKEIMDAANNTGSSVKKKEDTHKMAEANKAFAHYRW", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."}]}
+{"id": "function_test_3263", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPSLKDLKNRIASVKATQKITKAMKMVAAAKLRRAQEAAEAARPYSQRMAAVLSNIAQAVGADDSAPRLMTGTGKDDTHLLVVCTAERGLCGGFNSQIARHARDHVRKLLAQGKTVKIICVGKKGFDILRREFASLIIDRVDLREVKKIGFENADRIGHKVIELFDNGEFDVCTLFYSEFKSVISQIPTAQQLIPASAGEAVAEGASAIYEYEPDAAAILSDLIPRNISVQIFRALLENVAGEMGAKMSAMDNATRNAGEMINKLTLNYNRQRQAQITKELIEIISGAEAL", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex."}]}
+{"id": "function_test_3264", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAEKRAEKRKFNTDSWEPKTQVGRMVKEGTISDISYIMDKGLPLLEPEIVDVLLPDLEEQVLDVKLVQRMHKSGRRARYRATVVVGNKNGYVGVGMGKSKEVGPAIRKAIAQAKLSLIKVRVGCGSWECGCGSPHSIPFTAKGTCGSVKVELLPAPRGVGLVAGNVAKAVLGLAGVKDAWTTTYGDTRTTYNFAEATFDALNNLNFVRCLPEQKAKLGLTEGRVL", "output": "With S4 and S12 plays an important role in translational accuracy."}]}
+{"id": "function_test_3265", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPSAPQRPLFSRGSWPEARRLADVLRQETTGGLLLLVFTVIALVWANVAGNSYEEVRQFHLGPAALHLDLSIEHWAADGLLAIFFFVTGLELKKEFVAGDLRSPRAAALPIAAAVGGMAVPALLFVLVNVLHPDSPEGALVGWATPTATDIAFALGILAVVGSHLPSALRTFLLTLAVVDDLLGITVIAIFYTEQVHWTPLLLALLTLAAFTVAVQRRVRSWWLLVPLALATWALVHASGIHATVAGVLLGLVVPVLRSEEHGGPEAGPGLSEHFEHRWRPLSTGFAVPVFALFSAGVAIGGVSGFTAAVQDPVALGVIAGLVLGKPIGIVGTTWLLAKLTRAELDENLRWVDVLGMAMLAGMGFTVSLLIGSLAFGEGTAAGEHVTLGVLVGSLLSAVLAAVVLSRRNRVYRRIEAEERVDADGNGVPDVYER", "output": "Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons."}]}
+{"id": "function_test_3266", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRCPYCQSEDTQVKDSRPAEDGAVIRRRRVCSVCGGRFTTFERVQLRDLMVVKKSGRRVPFDRDKLTRSIEVALRKRDVDNDRVERAISGIVRQLESSGEAEVTSDEIGRLAMDALKGIDDIAYIRFASVYRNFSKAVDFHNVIDELTVAETEDDLDA", "output": "Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes."}]}
+{"id": "function_test_3267", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLRTTASRKIVLRRGLASINTGTTVASKKASHKFRNTFWTIALSATAFYAGGIIYSQKNDKFGDFFSNNVPFAEDLLETYEHYHDRPTLFLEDSWDGLKAKSNDLLSGLTGSSQTRRSNRENIEVKKILSLEPLNIETENSDPQLKEIIGSLNDLINSLNDSNLSIPESEFNSIKKSNQNMLTNLSQLNETLKEALSNYMIQRTSEVITELNTQYENSKREFEKNLQKNLLQEVDEFKENLTKQKDKELEEKLKANEELLQAKHANEVGLLSITQVKEFNKIIKDKIEKERNGRLAHLEEINSEVNDLSKSIDRSSKILSKNEALVQLTFQVDEIKSRINNNNLPDVNIDKELSRLKLLSNLLSTFNKKSCCDDGDCCSCKKGNKNEGKEGKISCKCKPKTNPPSLLSVALDELESTCSGKKILSNEQIYNRWNLLADDFKTASLLPPNSGILGQLTAKVFSLFLFTKTGNPSNATDFDSVYARVGDNLRVSNLNDAVEEVVSLKGWPHKVCESWIEDARRKLEVQRLVEILDCEIRTL", "output": "Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity)."}]}
+{"id": "function_test_3268", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSKKKGSNTLAENRKARHDYFIEETYEAGIELVGTEVKSIRQGKANLKDSYAEIRNGEVFVRNMHISPYEQGNIYNKDPLRDRKLLLHKSEIYKLVGFTTQQGYTLIPLSLYLKHGRVKVSLAVAKGKKNYDKRDAMLEKAAKREMDRQIKERSRY", "output": "Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation."}]}
+{"id": "function_test_3269", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIQSFTRLAVADNSGAKELMCIKVLGGSKRRYATLGDVIICSVKKALPNGKIKKGQVVKAVVVRTKKEVQRGNGSLIRFDENAAVILDNKREPIGTRIFGPVGREVRYANFMKIVSLAPEVL", "output": "Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome."}]}
+{"id": "function_test_3270", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNLEALCKEAELSFYDDELVSENGKKIYRIYVQKEGGVNLDDCARLSEILSPIFDVEPPVNGEYFLEVSSPGLERKLSKIEHFAKSIGELVKITTNEKEKIEAKIIAVDDENITLENLENKEKTTINFNDIKKARTFMEW", "output": "Required for maturation of 30S ribosomal subunits."}]}
+{"id": "function_test_3271", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTQHIVSGGPQVVDSESFSALTNVSRETLDRLLSYEALLRKWQKSINLVSNGSLPELWRRHMLDSAQLVCLVPESARRWIDLGSGGGFPGLVIAILLRERPGFQMHLVESDQRKCVFMREVARVTGAPATVHTVRIEAFAQGAEAGDVVSARALAPLDRLFGWAAPLFGPETIGLFLKGQGLQDELTLARESWIFDAEFSPSQSDPEGSVLKVRGLHGPDGQPHRR", "output": "Specifically methylates the N7 position of guanine in position 527 of 16S rRNA."}]}
+{"id": "function_test_3272", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MASQLVLRKADFFATPTQPVVVADRYPQNVFAEHTHEFCELVLVWRGNGLHVLNDRPYRITCGDLFYIRAEDRHSYQSVNDLVLHNIIYCPERLQLNVNWRDLLENPRGVNGDPRWRLSSQGMVQARQVIDQLEHESPKQDALSHCLAESLFLQLAITLRRHRYQPSGGTGPGEGETLDLLMAALGNSLDVPFDLQHFCSHYQIAERPLRQLFRQQTGMTISQYLRQLRICQAQYLLRHSSLLISEIAARCGFEDSNYFSVVFTRETGVTPRVWRQQWGALAG", "output": "Activates expression of the rhaSR operon in response to L-rhamnose."}]}
+{"id": "function_test_3273", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRHYEIVFMVHPDQSEQVAGMIERYTGSITEAGGKIHRLEDWGRRQLAYPINKLHKAHYVLMNVEAGQEVIDELETAFRFNDAVLRNMIMRTKAAITEQSIMLKQKEERAERAPRREERAEAKPEAAAE", "output": "Binds together with S18 to 16S ribosomal RNA."}]}
+{"id": "function_test_3274", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSQGYLEFPNIDPVLVSIGPVSVRWYGLMYLVGFMFALWLANRRADKPGSGWTREQVSDLLFAGFLGVVIGGRVGYVIFYNFDLFLADPLYLFKVWTGGMSFHGGLLGVITAMFWYAHKNGRTFFGVADFVAPLVPFGLGMGRMGNFMNSELWGRVTDVPWAIIFPNGGPLPRHPSQLYEMFLEGIVLFFILNWFIKKPRPLGAVSGLFLAGYGTFRFLVEFVREPDAQLGLFGGYISMGQILSSPMIILGILMMVWAYKRGLYQDKVQAETK", "output": "Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins."}]}
+{"id": "function_test_3275", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MVKLAFPRELRLLTPSHFTFVFQQPQRAGTPQITILGRLNSLGHPRIGLTVAKKNVRRAHERNRIKRLTRESFRLRQHELPAMDFVVVAKKGVADLDNRALSEALEKLWRRHCRLARGS", "output": "RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme."}]}
+{"id": "function_test_3276", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNETNDIDQLIYLFSKLPGLGSRSARRIVLYLLQDKDVRLKSLINNLINIDKKIVKCEICGNMDTENICRICSSEYRDKSVIAIVETVAELWAMERSGNFKGLYHVLGYNLSAASRKNPSMLRLPELLTRCFAANIKEVIIATNSTLEGQTTAYFITEYLKEHPAKISRLASGIPIGGELDYLDEGTLSAAINLRQPFE", "output": "May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO."}]}
+{"id": "function_test_3277", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKTLLLTLVVVTIVFLDLGYTMTCCNQQSSQPKTTTTCAESSCYKKTWRDHRGTITERGCGCPNVKPGVQINCCKTDECNN", "output": "Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission."}]}
+{"id": "function_test_3278", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAVNVQQYLNKEYEVECDGQMVRLKPVKAWVLQPKGRKGVVIGLFKCPNGKTLRKAIGKIE", "output": "A probable chromatin protein, binds double-strand DNA without sequence specificity. Constrains negative DNA supercoils."}]}
+{"id": "function_test_3279", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKYTRHSKILELIDKNEIETQEELSERLKDMGFTVTQATVSRDIKELRLIKVLTKNGKYKYATLQSQENILSDRVVKIFKNSVVSIDYAGNLIVIKTLTGSAQAAAAAIDAGDMNDVVGTIAGDDTIFIVIRDEKNVPSTIEHFRKLMK", "output": "Regulates arginine biosynthesis genes."}]}
+{"id": "function_test_3280", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MASEIFGTAAVFWVLIPVGLLGGAILLKLQGD", "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions."}]}
+{"id": "function_test_3281", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MERKERLRAGIAAMGLDILETAQDRLLAYVDLLKKWNKTYNLTALRDEEKMIVHHLLDSLTLLPYIEGAQTMLDVGSGGGQPGIPAAVCRPDVQITLLDANTKKTAFLQQAVIELGLDNVRVVSGRVEAVSDVRADVITSRAFAELADFVSWTGHLLKDGGYWAAMKGVYPQGEIDRLPQDVCVEKVQRLDVPGLDAERHIAILRKR", "output": "Specifically methylates the N7 position of guanine in position 527 of 16S rRNA."}]}
+{"id": "function_test_3282", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSKRIAGPEIERLIQLLARVPGLGPRSARRAALHLIKKKEALLVPLGGAMQEAAEKVRICSCCGNVDTSDPCTICTDERRDPATLIVVEDVSDLWALERAGTMNVRYHVLGGRLSPLDGIGPDDLNIKGLVERVASGAIKEVILAVNATVEGQTTAHYITDQLSNFDVRVTRLAHGVPVGGELDYLDEGTLAAALRARTTL", "output": "May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO."}]}
+{"id": "function_test_3283", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MENQPKLNSSKEVIAFLAERFPLCFTAEGEARPLKIGIFQDLVERVQGEENLSKTQLRSALRLYTSSWRYLYGVKVGAERVDLDGNPCGVLEEQHVEHARKQLEEAKARVQAQRAEQQAKKREAAIAAGETPEPRRPRPAGKKPAPRREAGAAPENRKPRQSPRPQQVRPPRPQVEENQPRPVPVTDISKLQIGQEIKVRAGKSAMDATVLEIAKDGVRVQLSSGLAMIVRAEHLQF", "output": "RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism."}]}
+{"id": "function_test_3284", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNEKPVLGIQDIQNLLPHRYPFLLVDKILSYDLNTRSVVAQKNVTINEPFFAGHFPGAPIMPGVLILEALAQAAGVLLGIILENDRDKKIALFLGIQKAKFRQPVKPGDVLTLKAEFSLISAKGGKAFAQAFVGSQVVAEGELSFVLVKKESI", "output": "Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs."}]}
+{"id": "function_test_3285", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIYHEIYDVIVVGGGHAGTEAALAPARMGLKTLLLTHNVDTLGQMSCNPAIGGIGKGHLVKEIDAMGGLMAIAIDQAGIQFRTLNSSKGPAVRATRAQADRVLYRQAVRTALENQPNLDIFQQEVVDILVENNRAVGAVTKMGLTFKARSVVLTAGTFLAGKIHIGLDNYAGGRAGDPSATMLADRLRDLNLRVDRLKTGTPPRLDARTINFDVLAKQHGDAELPVMSFMGAVDLHPRQIPCYITHTNEQTHDLIRNSLDRSPMYTGVIEGSGPRYCPSIEDKVMRFSDRNSHQIYLEPEGLSTIEVYPNGISTSLPFDVQMGIVNSMKGLEKTRIIKPGYAIEYDYFDPRDLKPTLETKAIEGLFFAGQINGTTGYEEAAAQGLLAGINAALQVQGKEAWFPTRDLAYTGVLVDDLCTLGTKEPYRVFTSRAEYRLLLREDNADIRLTPIAHELGLIDDARWARFNQKMENIERERERLKQIWIHPQSEHLAVVNELVNSPLTREASGEDLLRRPEVTYDKLTQVAAFAPALDDKQAAEQVEISIKYQGYIEHQQNEIERHKRHENTLIPAEFDYDKVESLSNEVRAKLMQHRPVSIGQASRISGITPAAISILLVNLKKQGMLKRGEL", "output": "NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34."}]}
+{"id": "function_test_3286", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRDMMGMMKQAKELQAKMKAMQDEIATMEASASSGGGLVTVTLSGKGTLSALKIDPSLMKEDEVEILEDLIIAAHNDAKAKLEAAMAEKTQSLTAGLPIPPGFKLPF", "output": "Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection."}]}
+{"id": "function_test_3287", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRDYIVRATAYNNKILAIAAFSTQTAQKAKEIHNLTPTTCAALGRALTAVAMMRVMMKGEKDKVTLVIKGDGPIGNIVVVSNYPGIVKGYVGNPTVDLPLSEKGKLDVGKAVGKNGYVTVIKDIGLKEPYVGTVELQTGEIGEDIAYYFYTSEQVPSAVGVGVLVGKEGNVLASGGFIIQLLPNIEEEVVAKVEEALKNISSVTELLRKGYLPEDILNHILGEMGLNILERVDLKYECDCSQERFETAIIALGKEEIKKLIAEGQSVEAVCHFCGKKYLIEESRLKELLRIAEE", "output": "Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress."}]}
+{"id": "function_test_3288", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSTISRDSCPALRAGVRLQHDRARDQWVLLAPERVVELDDIALVVAQRYDGTQSLAEIAQTLATEFDADASEIETDVIELTTTLHQKRLLRL", "output": "Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway."}]}
+{"id": "function_test_3289", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAGLSKDQLIESISSMSVIELSELVKALEEKFGVSAAAPAPAVVAGTSPAVATEEKTEFNVILGSVGTSKINVIKVVREVTGLGLKEAKDLVDGAPKTVKENVAKAEAEEIKKKFTEVGATVELK", "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation."}]}
+{"id": "function_test_3290", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNKKQLNFEKSLKKLEEIVSEIENADPDLDKALALFAEGAELIKSCLAKLNETKKKIEVIISSGKTEFFKE", "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."}]}
+{"id": "function_test_3291", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPTKYEAGTFDVIVIGAGHAGSEAAHAAAKMGAKTLMLTINLDMIAFMPCNPSIGGPAKGIVVREIDALGGVMGKVIDKTHIQMRMLNTGKGPAVRALRAQADKVLYQQEMKRILEETENLTIHQGMVEELIIEDGEVTGVITQIGAIYRAKTVVVTTGTFLRGEIIIGDIKYSSGPNNQQPSIRLADNLKELGFDLVRFKTGTPPRVNNRTIDYDKTEIQPGDEVPRAFSFETTEFIMDQLPCWLTYTSPETHEIIEANLHLSPMYSGMIKGTGPRYCPSIEDKVVRFNDKPRHQIFLEPEGRNTREVYVQGLSTSLPEHVQTRLLKSIPGLENAEMMRAGYAIEYDSIVPTQLWPTLETKRIKGLYTAGQINGTSGYEEAAAQGLMAGMNAAANVLGKEELILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLLELAYKIGMVPQERYDKFNAKKALIENEIARLREIIIKPNEATQAVIRSAGGSELKDGIRGADLLKRPEMHYEMISSLIPADIEFTEEVKEQIEIQLKYEGYIEKALLQVEKLHKMENKKIPENIDYDAISGLATEARQKLKQVTPLSIAQASRISGVNPADISILLVYIEQGKIAKISG", "output": "NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34."}]}
+{"id": "function_test_3292", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSFQEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLAKRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKVEAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQQYRDMTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATLTKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTDEEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVKDRLEADAAKKGEAHA", "output": "The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine."}]}
+{"id": "function_test_3293", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MINDIKKDAQDRMGKSIEALGRNLASIRTGRAHPSILDSVKVPAWGSEMPLNQVAAVSVEDARTLKIVAHDKNLSAAIEKAILTSDLGLNPSSAGTTIRVPMPALTEETRKGYTKQASAVAEDAKVAVRNVRRDALADLKKLTKDKEISEDEERRAADEIQKLTDKFVAEIDAAFKAKEKDLLAV", "output": "Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another."}]}
+{"id": "function_test_3294", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTIVNLAAYHFVSLDANEQWRPLVTARCNELGLRGTILLAPEGINLFIAGTREATDAFIAYIRHDPLFEGKFATLQFKESLSDSQPFRRMLVRLKREIITMKKPAIKPELGRAPFVDARTLKAWLDRGHDDAGRPVVMLDTRNAFEVDVGTFDNALDYRIDKFSEFPEVIDANRADLEGKTVVSFCTGGIRCEKAAIHMKEIGIDNVYQLEGGILKYFEEVGGAHYHGDCFVFDYRTALNPQLQPTENVTCFACRAVVTPEAQQSPSYVPGKSCPACAQAASAA", "output": "Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs."}]}
+{"id": "function_test_3295", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSLLAQLDQKIAANGGLIVSCQPVPDSPLDKPEIVAAMALAAEQAGAVAIRIEGVANLQATRAVVSVPIIGIVKRDLEDSPVRITAYIEDVDALAQAGADIIAIDGTDRPRPVPVETLLARIHHHGLLAMTDCSTPEDGLACQKLGAEIIGTTLSGYTTPETPEEPDLALVKTLSDAGCRVIAEGRYNTPAQAADAMRHGAWAVTVGSAITRLEHICQWYNTAMKKAVL", "output": "Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)."}]}
+{"id": "function_test_3296", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSRFLICSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMAAAMLFAGKVADRSGRKPVAIPGAALFIIASVFCSLAETSTLFLAGRFLQGLGAGCCYVVAFAILRDTLDDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKFPWQSLFWAMAMMGIAVLMLSLFILKETRPAAPAASDKPRENSESLLNRFFLSRVVITTLSVSVILTFVNTSPVLLMEIMGFERGEYATIMALTAGVSMTVSFSTPFALGIFKPRTLMITSQVLFLAAGITLAVSPSHAVSLFGITLICAGFSVGFGVAMSQALGPFSLRAGVASSTLGIAQVCGSSLWIWLAAVVGIGAWNMLIGILIACSIVSLLLIMFVAPGRPVAAHEEIHHHA", "output": "Confers resistance to chloramphenicol."}]}
+{"id": "function_test_3297", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKIRHWSALSLFVLPALAQAEALTGEVHRQPLNIQAIVMFLLFVGGTLYITYWASKRTRSRQDYYTAGGRITGFQNGLAIAGDYMSAASFLGISALVYASGYDGLIYSIGFLIGWPIILFLIAERLRNLGRYTFADVASYRLQQRPIRTLSACGSLVVVALYLIAQMVGAGKLIQLLFGLNYHVAVVLVGILMVLYVLFGGMLATTWVQIIKAVMLLSGATFMAIMVMKSVNFNFNTLFSEAVKVHPKGLSIMSPGGLVSDPISALSLGLALMFGTAGLPHILMRFFTVSDAKEARKSVFYATGFIGYFYILTFIIGFGAILLVGPNQTFKDAAGALLGGNNMAAVHLANAVGGSFFLGFISAVAFATILAVVAGLTLAGASAVSHDLYASVIKKGKANERDELRVSKITVIILGIVAIGLGILFEKQNIAFMVGLAFSIAASCNFPIIIISMYWDKLTTRGAMIGGWLGLSTAVILMILGPTIWVTILGHEKPIYPYEYPALFSMIAAFVGTWFFSITDNSETGKQERLLFKSQFVRSQTGLGASKGGAH", "output": "Transports acetate."}]}
+{"id": "function_test_3298", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSSGGLLLLLGLLTLWAELTPISSRERHPDCDKPPDTGRCGNNVRAFYYKPSTNKCVQFIYGGCNANGNHFKSDHLCRCQCREND", "output": "Beta-1-bungarotoxin is a presynaptic neurotoxin of the venom. The B chain is homologous to venom basic protease inhibitors but has no protease inhibitor activity and blocks voltage-gated potassium channels (Kv) (By similarity)."}]}
+{"id": "function_test_3299", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQKVTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWLKDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQFSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK", "output": "Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)."}]}
+{"id": "function_test_3300", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDVFNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIAIPPSLLNMYKELENTIPGFTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVVFLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGETPIDWMPVLPAESE", "output": "Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine."}]}
+{"id": "function_test_3301", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MARYDLVDRLNTTFRQMEQELAAFAAHLEQHKLLVARVFSLPEVKKEDEHNPLNRIEVKQHLGNDAQSLALRHFRHLFIQQQSENRSSKAAVRLPGVLCYQVNNLSQAALVSHIQHINKLKTTFEHIVTVESELPTAARFEWVHRHLPGLITLNAYRSLTVLHDPATLRFGWANKHIIKNLHRDEVLAQLEKSLKSPRSVAPWTREEWQRKLEREYQDIAALPQNAKLKIKRPVKVQPIARVWYKGDQKQVQHACPTPLIALINRDNGAGVPDVGELLNYDADNVQHRYKPQAQPLRLIIPRLHLYVAD", "output": "Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence."}]}
+{"id": "function_test_3302", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MALLPDKEKLLRNFLRCANWEEKYLYIIELGQRLPELRDEDRSPQNSIQGCQNQVWIVMRQNAQGIIELQGDSDAAIVKGLIAVVFILYDQMTPQDIVNFDVRPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAAALS", "output": "Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process."}]}
+{"id": "function_test_3303", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGLHAYPKAARLTKTDEFSSVFALRPVRRSRHFVLYVRANGDRPARLGVVIGKKFAKRAVERNLIKRQCRELFRLRQPLLGGRDVLIRLQAKFPRQDVPTVAAFKRICREELAQLFEVATRPLSAPPAATPPQPTAGSTP", "output": "RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme."}]}
+{"id": "function_test_3304", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MALLEIIHYPSKILRTISKEIVSFDSKLHQQLDDMRETMIASEGIGLAAIQVGLPLRMLIINLPREDGVQHKEDCLEIINPKFIETKGTIMYKEGCLSVPGFYEEVERFEKVKIEYQNRFAEVKVLEASELLAVAIQHEIDHLNGVLFVDKLSILKRKKFEKELKELNKNPKSKS", "output": "Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions."}]}
+{"id": "function_test_3305", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MVNWQVIGQLLSATLIVLAGPAVIFVLAFKKGNL", "output": "A core subunit of photosystem II (PSII)."}]}
+{"id": "function_test_3306", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "QTFHYSQGWTN", "output": "Cardioactive peptide. Corazonin is probably involved in the physiological regulation of the heart beat (By similarity)."}]}
+{"id": "function_test_3307", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "ARSDNFVRL", "output": "FMRFamides and FMRFamide-like peptides are neuropeptides."}]}
+{"id": "function_test_3308", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPRSLKKGPFIDFKLEKRILDLNAKDEKKVVKTWSRSSMISPDFVGHTIAVHNGKTHVPVYVSDNMVGHKLGEFAPTRTFRGHAGGKAEKGGSAPRKK", "output": "Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA."}]}
+{"id": "function_test_3309", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSEALTELASYLGEARGNLIAASQLKYGELTLTATGENLIPLLTFLRDDAKCGFVNLIDICGVDWPQRELRFDVVYHLLSPKKNLRIRVKVATDEDTPVPSACGLYPGADWFERETWDMYGVLFTGHPDLRRILTDYGFEGHPLRKDFPTTGFVEVRYDDAAKRVVYEPVELKQEFRNFDFMSPWEGTEYVLPGDEKAKQ", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_test_3310", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGGGVRRGFEGGQMPLYRRLPKFGFTSRKAAITAEVRLSDLAKVEGGVVDLNTLKAANIIGIQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE", "output": "Binds to the 23S rRNA."}]}
+{"id": "function_test_3311", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRSSAKQEELVRAFKALLKEEKFSSQGEIVLALQDQGFENINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPASGFSVRDLYEAILELFEQEL", "output": "Regulates arginine biosynthesis genes."}]}
+{"id": "function_test_3312", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQLDEHHAVRTDAGMFDVSHMTIVDLHGSRTREFLRYLLANDVAKLTKTGKALYSGMLNASGGVIDDLIVYYFTEDFFRLVVNSATREKDLSWITQHAEPYAIDITVRDDLSLIAVQGPNAQEKAATLFTDQQRHAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIAMPNEKAADFWRALVEAGVKPCGLGARDTLRLEAGMNLYGQEMDEGISPLAANMGWTIAWEPADRDFIGREALEMQREKGHEQLVGLVMTEKGVLRNELPVRFTDAQGNQQEGIITSGTFSPTLGYSIALARVPAGIGETAIVQIRNREMPVKVTKPVFVRNGKAVA", "output": "The glycine cleavage system catalyzes the degradation of glycine."}]}
+{"id": "function_test_3313", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPKKNEAPASFETALSELEHIVTRLESGDLPLEDALNEFERGVQLARQGQAKLQQAEQRVQILLSDNEEASPEPFIADNE", "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."}]}
+{"id": "function_test_3314", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRLWKSMAWGILLWHSQSGALCPAWPPARAAEEIARLQQQLADWNDIYWKQGVSAVDDSVYDQLSARLVQWQRCVGQDVSSTPVSPPLNGTTMHPVAHTGVRKLADRQAVEQWMRGRSELWVQPKVDGVAVTLVYQNGKLTRAISRGNGLQGEDWTPKIRLIPSIPQTTQGALANAVLQGEIFLQREGHIQQRMGGMNARSKVAGMLMRQDNASALNSLGIFIWAWPDGPANMPERLSQLAKAGFSLTKKYSLVVKDASEVERARQSWLTSALPFVTDGVVIRMAKEPASQYWRPGQGDWLAAWKYPPVAQVAQVSAIQFSVGKSGKITVVASLVPVILDDKRVQRVNIGSVKRWEAWDIAPGDQILVSLAGQGIPRLDEVVWRSRERSKPVPPDSHFNSLTCFYASATCQEQFISRLVWLGSRSALGLDGMGEASWRALHQTHRFEHIFSWLTLTSAQIANTPGFAKGKSEQIWRQFNLARRQSFTRWIMAMDIPLTQAALQASGDRSWEQLLMRTEQHWRQLPATGERRAGRVIDWRNNPQIKTLSRWLAAQHIPGFGS", "output": "Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction."}]}
+{"id": "function_test_3315", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSITKDQIIEAVSAMSVMDVVELISAMEEKFGVSAAAAVAVAAGPAEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKDDAEALKKSLEEAGAEVEVK", "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation."}]}
+{"id": "function_test_3316", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSTSTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLTEVQSEFGLTTVQAASLISAAFISRWFGGLLLGAMGDRYGRRLAMVSSIILFSVGTLACGFAPGYTTMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVAAQVYSQVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHAGKAPVRTMVDILYRGEHRIINILMTFAAAAALWFCFAGNLQNAAIVAGLGLLCAVIFISFMVQSSGKRWPTGVMLMLVVLFAFLYSWPIQALLPTYLKTELAYDPHTVANVLFFSGFGAAVGCCVGGFLGDWLGTRKAYVCSLLASQILIIPVFAIGGTNVWVLGLLLFFQQMLGQGIAGILPKLIGGYFDTDQRAAGLGFTYNVGALGGALAPILGALIAQRLDLGTALASLSFSLTFVVILLIGLDMPSRVQRWLRPEALRTHDAIDDKPFSGAVPLGSGKGAFVKTKS", "output": "Catalyzes the proton-dependent transport of sialic acid."}]}
+{"id": "function_test_3317", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLTKELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQINIAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGAEIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPEKPAAQPKKQQRKGRK", "output": "Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation."}]}
+{"id": "function_test_3318", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSSGGLLLLLGLLTLWAELTPVSGQDRPVKPGLCPPRPQKPPCVKECKNDWSCRGEQKCCRYGCIYECRDPIFVK", "output": "Damages membranes of susceptible bacteria. Has no hemolytic activity. Not toxic to mice. Does not inhibit the proteinases elastase and cathepsin G."}]}
+{"id": "function_test_3319", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSSVPAPREYFLDSIRAWLMLLGIPFHISLIYSTHSWHVNSATPSWWLTLFNDFIHAFRMQVFFVISGYFSYMLFLRYPLKRWWKVRVERVGIPMLTAIPLLTLPQFILLQYVKEKTENWPTLSAYEKYNTLAWELISHLWFLLVLVILTTVSIGIFTWFQKRQETSKPRPAAISLVRLSLIFFLLGMAYAAIRRIIFIVYPAILSDGMFNFIVMQTLFYVPFFILGALAFIHPDLKARFTTPSRGCTLGAAVAFIAYLLNQRYGSGDAWMYETESVITMVMGLWMVNVVFSLGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHISSNLIGFLCGLIFVMGIALILYEIHLRIPLLKFLFSGKPPVKQESRAAIG", "output": "Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane."}]}
+{"id": "function_test_3320", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAKLHDYYKDEVVAKLMTEFNYNSVMQVPRVEKITLNMGVGEAIADKKLLDNAAADLTAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFERLITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTAKSDEEGRALLAAFDFPFRK", "output": "This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs."}]}
+{"id": "function_test_3321", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNHAITMGIFWHLIGAASAACFYAPFKKVKHWSWETMWSVGGIVSWLILPWAISATLLPDFWAYYRSFNASTLLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIVGTLMTPIINGQFSVLMHTQGGQMTLLGVLVAVIGVGIVTRAGQLKERKMGIKAEEFNLKKGLLLAVMCGIFSAGMSFAMNAAKPMHDAAAALGVDPLYAALPSYVVIMGGGALVNLGFCFIRLAKVKNLSVKADFSLAKPLIISNLLLSALGGLMWYLQFFFYAWGHASIPAQYDYMSWMLHMSFYVLCGGLVGLVLKEWNNAGRRPVSVLSLGCVVIIIAANIVGLGMAS", "output": "Uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell (symport system)."}]}
+{"id": "function_test_3322", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGAVDTSERLSKLRQLMQQHKVDVYIVPSEDSHQSEYIAPCDARREFISGFSGSAGTAIISLSKAALSTDGRYFNQAAKQLDNNWQLLKGGVEGVPTWQEWTTEEAQGGKAVGVDPSLITASGARKLAETLKKNGSSLVGVRENLVDLVWGKERPARPSEKVRVHPEKYAGKTFQEKVAELRKELESKKKAGFVISMLDEIAWLFNLRGTDIPYNPVFFSYAVITPTTAEIYVEDDKLTPEVKAHLGQDVVVKPYESIFADAQALSTKSQSAGENAAKFLLSNKASWALSLSLGGEGQVEEARSPVADAKAIKNETELEGMRACHIRDGAALTEYFAWLENELINKKTVLDEVDGADKLEQIRSKHDLFAGLSFDTISSTGPNGAVIHYKPEKGSCAIIDPSAIYLCDSGCQYFDGTTDTTRTFHFGVPTEFEKRAFTLVLKGTIGIDMAVFPKGTSGFAIDVLARQHLWREGLDFLHGTGHGVGSYLNVHEGPIGIGTRVQYTEVPIAAGNVISDEPGYYEDGKFGIRIENIVMAREVKTAHNFGDKQWLGFEHVTMTPIGRNLIEPSLLSDAELKWVNDYHAEIWAKTEHFFREDNLTRSWLERETQPISK", "output": "Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides."}]}
+{"id": "function_test_3323", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MFRQAKWDEPLIFELSRSGRVGYTLPKPIEDVEIRVPEKLKRKSPLNLPELSEPEVVKHYTRLSGMNYGVDSGIYPLGSCTMKYNPKINEEIAGHPGVAYVHPYQDERTIQGALKIMWELEGWLKEITGMDRFTLQPAAGANGEFTGVMIIRAYHLDRGETQRTEMLVPDSAHGTNPASAAMAGFKVIEIPSNENGTVDLEALENAVSERTAGLMLTNPNTLGIFEDEILEIAKIVHKAGGLLYYDGANLNAVLGKIRPGDMGFDIVHLNLHKTFSTPHGGGGPGSGPVGVKDFLKDYLPVPLVGYDEESGRYYLDYNVPKSIGKVKELYGNFAVMVRALTYLKIMGRDGLKEASEIAVLNANYLTQKLKGTRGYELPHKELRKHEVVFSAEPMKKETGVKALDVAKRLLDFGLHAPTIYFPLIVHEALMIEPTETVSREELDAYVEALKRISEEAYSNPELVKSAPHNTAVKRVDDVLAAKRPIITWRMYRELKEKGEVDI", "output": "The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein."}]}
+{"id": "function_test_3324", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAQNKANTVSQLQSLKNKSGKSYNQLAEETGLTNVYVAQLLRRQAHLKPETAPKLKAALPELPEELIHEMMKPPLRSYDPNIIQDPTVYRLNEAVMHFGESIKEIINEEFGDGIMSAIDFYCSVDKVQGVDGKDRVVLTFDGKYLPHSEQKTEHMVSRTRPLEKQ", "output": "Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide."}]}
+{"id": "function_test_3325", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKIDIVSVFPEYFEVMNLSLMGKAQAKGLLEIKAHNLRDWTHDVHHSVDDTPVGGGAGMVMKPEVWSECLDELLGFSRPSDSSAPSGTPVLIFPNPSAPLFTQRDATELSHADHLLFGCGRYEGYDARIPDYYRSQGVDVREYSIGDYVLNGGEVAVSVMLEAITRLMPGFMGNPDSIVEESYTGEGALLEHRQYTKPAVWRGIAVPDVLLSGDHGKVDRFRRDEALARTAEIRPDLIAALDCKALDKADRKTLMALGWEVSAAHPRRLAD", "output": "Specifically methylates guanosine-37 in various tRNAs."}]}
+{"id": "function_test_3326", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAKYTNDELLEAFGEMTLVELSEFVKAFEEKFDVEAAAPVAAVAAVAGAAAPAEEEKDEFDVILSAVGDKKIQVIKAVRAITSLGLAEAKALVDGAPKAVLEKAKKEDAEKAKAQLEEAGASVELK", "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation."}]}
+{"id": "function_test_3327", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSIQVFCDFDGTITNNDNIMSIMEKFAPPEAEEVKNKILSQELSIQEGVSQLFQLIPTNLHDDIIQFLIETAEIRSGFHEFIQFVKENNISFYVISGGMDFFVYPLLQGIIPKEQIYCNETDFSAEFITVKWPHSCDDHCQNHCGLCKSSLIRKLSDTDDFHIVIGDSITDLQAAKQADKVFARDFLITKCEENHIAYTPFETFQDVQAELKLLLEVKA", "output": "Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene)."}]}
+{"id": "function_test_3328", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSIPNNLRYSEEHEWVKTEGNEVVIGITHFAQNELGDIVFVELPEVGATIEADEPFGSVESVKTVSELYAPVSGKVVAVNEELSDQPELVNESPYEGAWMVKVELSDASQVEKLLTAEKYAEMTNQD", "output": "The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.; "}]}
+{"id": "function_test_3329", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLTIAIPKGALLSDAIKLFQSIGLDFSAFLDPKNRQLQITDPTNTAKALLVRATDVPVYVEYGQAQLGIVGYDLLLEKTPTVANLANLKFGYCRMSVAVPASSPYKSPVELPPNGKVASKFVNCAKKYFHTLDLPVEIIPLYGSVELGPITGMSEAIVDLVSTGRTLKENGLIEIDTLFESTAHLIAHPLSYRLNLDQINPWVTKIRDTLS", "output": "Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity."}]}
+{"id": "function_test_3330", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPKADIHPTWYPEAKIICNGEVVMTVGSTQPEIHVEVWSGNHPFYTGTQKMIDTEGRIDRFQKRYGNLGKGGSKPNKKGDQK", "output": "Binds the 23S rRNA."}]}
+{"id": "function_test_3331", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKRIAFVFSTAPHGTAAGREGLDALLATSALTDDLTVFFIADGVFQLLSGQKPDAVLARDYIATFKLLGLYDIEQCWVCAASLRERGLDPQTPFVVEATPLEADALRRELANYDVILRF", "output": "Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions."}]}
+{"id": "function_test_3332", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRFAIVVTGPAYGTQQASSAFQFAQALIVEGHELSSVFFYREGVYNANQLTSPASDEFDLVRGWQQLNAQHGVALNICVAAALRRGIVDETEAGRLGLASSNLQPGFTLSGLGALAEASLTCDRVVQF", "output": "Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE."}]}
+{"id": "function_test_3333", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGIMHTSELLKHIYDINLSYLLLAQRLIVQDKASAMFRLGINEEMATTLAALTLPQMVKLAETNQLVCHFRFDSHQTITQLTQDSRVDDLQQIHTGIMLSTRLLNDVNQPEEALRKKRA", "output": "Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways."}]}
+{"id": "function_test_3334", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSQSTSVFRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAGVKRCLDIGAGSGLLALMLAQRTDDSVMIDAVELESEAAAQAQENINQSPWAERINVHTADILQWITQQTVRFDLIISNPPYYQQGVECATPQREQARYTTTLDHPSLLTCAAECITEEGFFCVVLPEQIGNGFTELALSMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFSDRLVIRGPDQNYSEAYTALTQAFYLFM", "output": "Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)."}]}
+{"id": "function_test_3335", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLTLARQQQRQNIRWLLCLSVLMLLALLLSLCAGELWILPGDWFSPRGELFVWQIRLPRTLAVLLVGAALAISGAVMQALFENPLAEPGLLGVSNGAGVGLIAAVLLGQGQLPNWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALMTWAIYFSTSVDLRQLMYWMMGGFGGVDWRQSWLMLALIPVLLWICCQSRPMNILALGEISARQLGLPLWFWRNVLVAATGWMVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGASALLLADIVARLALAAAELPIGVVTATLGAPVFIWLLLKAGR", "output": "Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane."}]}
+{"id": "function_test_3336", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDWKKEFIDFSFKKKVLKFGVFQLKSGRISPYFFNSGLLSTGIDIIKIGLFYARSIIDSKNKFDVLFGPAYKGIPIAVATSIALKNHYNLNVPYSFNRKEYKEHGEKGDLIGSTIYKKRVIILDDVITSGTAIHHSIKIIEKQEASISSIFVLLDRKEKGIRKLSTINHFRNQKSYKIISIITIDDLIEYVLEDKKLKEHIPQLIKYREKYGI", "output": "Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)."}]}
+{"id": "function_test_3337", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFNLRNFDVIVVGAGHAGTEAAMASSRMGCKTLLLTQKISDLGALSCNPAIGGIGKSHLVKEIDALGGMMAKAIDYSGIQFRILNSSKGPAVRSTRAQADKILYHETVKKILKKQNNLLILEAEVKDLIFKNYSVVGVLTQNEINFYSRSVVLAAGTFLGGKIHIGLKSYSAGRIGDKSAIDLSVRLRELSLRVNRLKTGTPPRIDINTVNFNNLLIQNSDTPVPVFSFMGNVSHHPKQIPCYLTHTNEKTHEIIRKNLDKSPIYTGFLKGLGPRYCPSIEDKIVRFPDRKSHQVFLEPEGLSSIKVYPNGISTSLPIEVQEQIVASIKGLEKSKIIRPGYAIEYDFFDPKDLNLTLESKLIKGLFFAGQINGTTGYEEAASQGLLAGLNAALSSKNTEGWFPRRDQAYLGVLIDDLTTQGTEEPYRMFTSRAEYRLSLREDNADLRLTEIGRKLGLVNDSRWIRYNQKVLNIQTEMNRLKKNKISPISPDADILKKLYNISLIKEISMSELLKRPQIRYQDLQSLESFRTGIVDLEAIGQIENEIKYAGYIKRQSEEIERHLKNENTFLSSICDYNKIRGLSSEVVKKLNDYKPISIGQASRISGITPAAISILLIHLKKESYKHTL", "output": "NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34."}]}
+{"id": "function_test_3338", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MALSIHDKKIIVSKINKISNTALSAVTADLQGVCVNKINELRKSGREVGVKMSIVQNTLLSLAIKNTVFECLKKKLKGSTFIAYSMIHPGSGARLFKEFSKKNTQFKITGAAFEGKLLSILEINQLADMPTYKEAIIKLLLTWKMLIAGKLIYTLSAIKQKKETS", "output": "Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors."}]}
+{"id": "function_test_3339", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTMYAKNNTAGKDMLSLLEWNKEELTDIIKLAVAMKTNPAHYSHILSGKILGMIFDKPSTRTRVSFEAGILQLGGQAIVMSSKELQIGRGEPIKDTAHVMSEYIDAIMIRTFSHEKVEELAYHAEIPIINGLTDLHHPCQALADLMTIYEWKDQLEGVKLAYIGDGNNVCHSLLLAGAMVGLDIRLAMPKGYEVDETILATAENLAKESGAKIFVTVDPKHAVADADFIYTDVWTSMGQEEENAKRLADFGEKYQVNAELASVAKPDYHFLHCLPAHREEEVTAEIIDGNHSVIYQQAGNRLHAQKALLAAILEAK", "output": "Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline."}]}
+{"id": "function_test_3340", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTEYALILISTVLVNNFVLVKFLGLCPFMGVSRKVETATGMGLATTFVLTLSSVCSYLVNEYLLAPLGLEYLRTIAFILVIAAVVQFTEMVVHKTSPLLYNVLGIFLPLITTNCAVLGVALLNVQEAHGFIESALYGLGAAVGFSLVLVLFASIRERVAVADVPLPFKGNAIALITAGLMSLGFMGFIGLVK", "output": "Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane."}]}
+{"id": "function_test_3341", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRFDVVTLFPDFFTSPLASGLLGKALAKQIAEVYLLNPRDFTTDKHHRVDDESYGGGVGMVLKPEPIFAAVESLPVLPRREVILMSPQGERLDQALLQSLADNFDQLVVICGHYEGVDERVVDHLVTREISLGDFVLTCGEIPALTLLNGVIRLLPGTVGKAESLQNESFIDGLLDFPHYTRPADFRGWPVPQVLRSGHHAEVDRWRRTQQIQRTRDRRPDLYQRWLNSLPPDSLQDFTV", "output": "Specifically methylates guanosine-37 in various tRNAs."}]}
+{"id": "function_test_3342", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MADSKISPGMQQYLDIKAQYPDAFLLFRMGDFYELFYDDAVKAAQLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDILIELGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTVVDSAKPNSSNNFLIAIDFDGSHYGLSYMDLVTGEFFATTLSDFMSVCGEILNLKAKEVVIGFEITAEQEEQLQKQFRLLLSYEQEIYTDDTLINPNLSQVEKNVAGKLLQYVHQTQMRELSHLQELIHYDIKDYLQMSYATKSSLDLIENARTKKKHGSLYWLLDETKTAMGMRLLKTWIDRPLISKQAISERQNIVETFLESFIERSDLADSLKGVYDIERLSSRVSFGKVNPKDLLQLGHTLSQVPYIKAVLEAINSPHLSKVIATIDPIPELESLIHSAIDPDAPATISEGSIIKTGFDQRLDHYRKVMKEGTGWIADIEMKERQASGINNLKIDYNKKDGYYFHVTNSNLSLVPDHFFRKATLKNSERYGTAELAKIEGQMLEAREESAQLEYDIFMRIREKVETYIDRLQTLAKAIATVDVLQGLAYVAEKNHYVRPEFASQKVITIQNGRHAVVEKVMGVQEYIPNTIQFNQNTSIQLITGPNMSGKSTYMRQLALTVIMAQMGSYVAADYAKLPIFDAIFTRIGAADDLISGQSTFMVEMMEANQAIQRASHDSLIIFDELGRGTATYDGMALAQSIIEHIHNRIGAITLFATHYHELTSLSEELGHLKNVHVAILERDGEVTFLHKIAEGPADKSYGIHVAKIAGLPGSLLSRADNILKQLESHSKDFIIKDNSQQSEENEPLNLLTEETSSQDIINRLKEVDVMNMTPMEAMTVLFDLKKKIK", "output": "This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity."}]}
+{"id": "function_test_3343", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MILGIGTDLANIDRMEKTLARFGERFRNRVFTPLEQAKAERRADVAGTYAKRWAAKEACSKALGTGLRMGISWKDMSVANLETGQPVMRLTGWAAERLASMTPPGHEAVVHVSLTDDHPWAQAFVVIEARPRAAPPA", "output": "Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein."}]}
+{"id": "function_test_3344", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIGSVLQKVVAGQILDIDEAMEAMSAIMTGEATPAQIAALVTALRMRGERETEIAGFVKGLRAHMIPVELQLAQPVIDVVGTGGDGNRTFNISTATAFVVAGAGVPVAKHGNRAMSSRAGSADVLEALGVRIDLNPSAVARCVEEAGIGFMFAQRFHPALRHAAPVRRELGFRTVFNVLGPLANPARVRYQLLGVAMPELVETVARVLALLDVEHALVVHSADGLDEISLGAPTTVYEVRRNGTVEVRRWTLEPESLGLERVPSDALRGGTAEENARIVRAVLEGARGPARDVVLLNAAAALVAADAAQSLAEGLELARHAIDSGAALDRLERLKVLSNALAEAEVPS", "output": "Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)."}]}
+{"id": "function_test_3345", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIAFIEPFLASKSLANNSQQSYRYDLRQFCQQVGQRINPETLALYQQSLSGLTVAAKKRKLSTVNQFLYYLYQQKALTDYFKMDDRIEASFSLKPQLTRLDTSAFYAETAFLKGQLIALLILELGLTPSEIAGLRLADFDLGLQVLRLQSHRGIRVMTLSKALLPFLEKATEAQQLYLFDHDAKPFSRQWFFNQLRDFLESIGCAELSAQSLREQFILNEKAAGKSIIEVAQLLGLKSPITLEKYYKM", "output": "Putative tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site."}]}
+{"id": "function_test_3346", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MANHKSAAKRAKQSEARRLRNKSTRSSMNTAVKKVRTAKEAGTDNATDLLNSAKSLIAKAAKKGVIHQNTAARKISRLTKSLG", "output": "Binds directly to 16S ribosomal RNA."}]}
+{"id": "function_test_3347", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRSGVIAQKLGMTRVYNDAGEHVPVTVLRMENCHVVAQRTVEKNGYTAVQLGVGMAKVKNTSKAMRGHFAKAEVEPKAKLAEFRVSPDNLLEVGVEITAEHFVAGQKVDVTGTSIGKGFAGVMKRHNFGGHRASHGNSITHRSHGSTGQRQDPGKVFKGKKMAGHMGQTRVTTQNIEVVSTDSDRGLILVRGAVPGSKGAWILVRDAVKASLPENAPKPAGLRAGAKAEAAATEGGE", "output": "One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit."}]}
+{"id": "function_test_3348", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPIDTVMETLPGYAKDIKLNYSTLVRQNTELTPQQLWGTVVASAIATRNDTLTAAALEDGAQHLSEQALEAARIAAALMSMNNIFYRFQHLSSNEKYATMPARLRMNGMRTHGVEPVDFELWSLAVSAINGCGKCVDSHEKVLREKGAGEDLVLAAVRVASVIHAIGAVLDAEKVHQPEAAMA", "output": "Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity."}]}
+{"id": "function_test_3349", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTQVTVKQLADEVKTPVERLLQQMREAGLPHTAADEGVSDSEKQSLLTHLKSSHKAKVEEPRKITLQRKTTSTLRVAGSKSISVEVRKKKVFVQRSPEEIEAERKRELEERRAVENAARQKAEEEAKRRAEEEARRQPAAAQPAGTEAVAAPVAPVEAVREAAPVAAAPAPAADARKRDEPRRPDKPRADDNNRRGGGGDGERKNAPHRASVKEKAPAPRVAPRTTDEESDGFRRGGRGKAKLKKRNAHGFQSPTGPVVRDVQIGETITVGDLANQMSVKAAEIIKFMFKLGTPATINQVLDQETAQLVAEELGHKVTLVSDTALEDSLAESLKFEGETFSRAPVVTVMGHVDHGKTSLLDYIRRAKVAAGEAGGITQHIGAYHVETERGMVTFLDTPGHAAFTAMRARGAKATDIVILVVAADDGVMPQTIEAVQHAKAAGVPLVVAVNKIDKPGADLDRIRSELSVHGVTSEEWGGDTPFVSVSAKVGTGVDELLEAVLLQAEVLELKATPSAPGRGVVVESRLDKGRGPVATVLVQDGTLRQGDMVLVGSNYGRVRAMLDENGKPIKEAGPSIPVEILGLDGTPDAGDEMSVLSDEKKAREVALFRQGKFREVKLARAHAGKLENIFENMGQAEKKTLNIVLKSDVRGSLEALNGALNGLGNDEVQVRVVGGGVGGITESDANLALASNAVLFGFNVRADAGARKIVEQEGLDMRYYNVIYDIIEDVKKALTGMLGSDVRENILGVAEVRDVFRSPKFGAIAGCMVIEGTVYRNRPIRVLREDIVIFEGELESLRRFKDDASEVRAGMECGIGVKSYNDVKAGDKIEVYEKVQVARSL", "output": "One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex."}]}
+{"id": "function_test_3350", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTDLTRLTIAEARAKLSAKEITAVELTDAYIGAIEAANETINAYVTVTPEKARAMAKASDARIAAGKAGALEGIPLGIKDLFGTEGVHTQACSHILDGFRPRYESTVTQNLWNDGAVMLGKLNMDEFAMGSSNETSYYGPVKNPWRAKGSNMDLVPGGSSGGSAAAVAAYLCAGATATDTGGSIRQPAAFTGTVGIKPTYGRCSRWGVVAFASSLDQAGPIARDVRDAAILLKSMASVDLKDTTSVDLPVPDYEASIGQSIKGMKIGIPKEYRVDGMPEEIEALWQQGIAWLKEAGAEIVDITLPHTKYALPAYYIVAPAEASSNLARYDGVRYGLRVDGKDIVDMYEKTRAAGFGREVKRRIMIGTYVLSAGYYDAYYLRAQKVRSLIKRDFELAFQAGVDAILTPATPSSAFGIADEDLASDPVKMYLNDIFTVTVNMAGLPGIAVPGGLDHKGLPLGLQLIGKPFDEETLFKTAHVIEQAAGRFAPSKWW", "output": "Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)."}]}
+{"id": "function_test_3351", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTDLRHYDVIVSPSITEKSTLVSEQNQVVFNVAKGASKPEIKAAVEALFGVKVTAVNTLVRKGKLKRFRGFAGKQKDVKKAIITLAEGQSIDVSTGL", "output": "One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome."}]}
+{"id": "function_test_3352", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQGKSIRLGIVVAEFNYDITQLMLQKALSHAKFLNAEVKVVIKVPGTFDMPLAIKKLLEKDFIDAVVTLGAVIKGETKHDEIVASQTARKIVDLSTEFNKPVTLGIIGHGATHEQAVERIEEYATRAVEAAIKLVQRTRKIDELKEVKETVIID", "output": "Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin."}]}
+{"id": "function_test_3353", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQEVHQTPMMKQYFSIKADYPDAFLFYRLGDFYELFFEDAQIVAKELELTLTSKNGKQAEHPIPMCGVPHHSAAIYIEQLIEKGFNVAICEQTEDPKATKGLVKREVIQVITPGTYMASLSEKENRYLVAISDVAGRFGIARGDVTTGESWLTTLSSEEAVLREIEGLLPNEVIVEDERLADLLRQTGIPLSIQVDKRESTLAQGAKDEAQRSAFELLFAYLTKTQKRSLDHLQPAVAYEVEQHMQLDANTARNLELFRSARSGERKGSLLSLLDETTTAMGGRLLKRWLEQPLYTEQGIRERQDAVENLVDDFMLRDQLQEELKRVYDIERLVAKVGYGTANARDLVQLRDTLERMPSVRSLLQTVKADRLQQIEQNLDSFETLSEQLRAALVDSPPISTKEGGMIRHGYSDELDELLEAKANGKSWIANLEQQERIATGIKSLKVGYNRVFGYYLEVTKANAKLLEEGRYERKQTLTNAERYITPELKEKEALILGAEEKSCTLEYDLFVALREEVKTYTKPLQQLARSLSELDVLLALAVVAEKREYVRPVTTSHVQIERGRHPVIETVLPRGEYVANDLTLDDTRQMLLITGPNMSGKSTYMRQFALIAILHQIGSFVPAEAAELPLFDRIFTRIGAADDLVSGQSTFMVEMTETRQAVTEATSNSLILLDEIGRGTSTYDGMALAQAIVEYIASSIGAKTLFSTHYHELTVLEDSIPSLENVHVRAIERDGRVVFLHEVHPGRADKSYGIHVAELAELPDSLIDRARTILSELESEATKPALNEQSAPPQVEEVSQLSLFESNDAVREQLLKLDLLAMNPIEAMQALYELQQTAKKG", "output": "This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity."}]}
+{"id": "function_test_3354", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MHELSIAQSLLALIEDEMAKHGKEKLITVKVRHGRLSSVVPEALSMAFEVMTADSRLAGAALVMEETPVLLRCRDCSREFTPDPPTAAFAPCPGCGQELGHTVVSGRELYIEYLELE", "output": "Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase."}]}
+{"id": "function_test_3355", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLPTIITDIECLVTRPDRHNLVTVVVRTDKGITGYGCATFQQRPLAVKAMVDEYLKPLLVGRDANHIEDLWHMMMVNAYWRNGPVINNAVAGVDMALWDIKGKLADMPLYHLFGGKSRDAIAAYSHAASDTLDGLYQDVERLYTQGYRHIRCQLGFYGGNPDTLHSTRQPTEGAYYDQDQYMANTIAMFRALREKYGDRFHILHDVHERLFPNQAVQFAKAVEVYRPYFIEDILPPAQNEWLAQIRSQSAVPLATGELFNNPAEWQNLVINRQIDFIRCHVSQIGGITPALKLGAFCQNFGVRLAWHCPPDMTPIGAAVNIHLNIHLHNAAIQEFVAYPENTRKVFPQAVEPENGYLYPIERSGIGVGIDLDAARQFPVVYRPHEWTQSRLPDGTMHTP", "output": "Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function."}]}
+{"id": "function_test_3356", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTALDWRSALTADEQRSVRALVTATTAVDGVAPVGEQVLRELGQQRTEHLLVAGSRPGGPIIGYLNLSPPRGAGGAMAELVVHPQSRRRGIGTAMARAALAKTAGRNQFWAHGTLDPARATASALGLVGVRELIQMRRPLRDIPEPTIPDGVVIRTYAGTSDDAELLRVNNAAFAGHPEQGGWTAVQLAERRGEAWFDPDGLILAFGDSPRERPGRLLGFHWTKVHPDHPGLGEVYVLGVDPAAQRRGLGQMLTSIGIVSLARRLGGRKTLDPAVEPAVLLYVESDNVAAVRTYQSLGFTTYSVDTAYALAGTDN", "output": "Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol."}]}
+{"id": "function_test_3357", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQCAQYTAGHCHSCQWLNKSYSQQLSDKQQHLQQLLRETSATYWLPPVSSLISGFRNKAKMVVSGSVERPQLGMLHRDGRTVDLCDCPLYPQYFQLVFESIKIFIAKAGLVPYNVARKKGELKYILLTESRASGEMMLRFVLRSETKLAQLEHALPWLQEQLPQLTVISANIQPTHMAILEGEKEVIFTEHKMLKEIFNGIPLYIRPRSFFQTNPEIASALYATAGRWVRELNISSMWDLFCGAGGFGLHCADKETRLTGIEISAEAIACAKNSAKSLGLEQVEFQALDSTHFALDKAQLPELVLVNPPRRGIGKALCEYLSRMAPKFILYSSCNAETMAKDIAALEQYRIEKVQLFDMFPHTEHYETLALLIFDGK", "output": "Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA."}]}
+{"id": "function_test_3358", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAKLQLGYKASAEQFGPRELVEIAVAAEAAGMDSVAVSDHFQPWRVNGGHAPFSLAWMAAVGERTERVKIGTSVMTPTFRYNPAVIAQAFASMACMYPDRIFLGVGSGEALNEYATGFQGEWPEFKERFARLRESVRLMRELWSGEISNFDGDYYHTKDAVLFDIPERPVPVYIAAGGPVVAKYAGRAGDGMICTSGKGMDLYTEKLIPAAKEGAELGGRDFDALDKMIEIKISYDPDPELALENTRFWAPLSLTAEQKHSVNSSAEMERLADELPIEQVAKRWIVASDPDEAVAAVKQYTDAGLNHLVFHAPGHDQRRFLDNFQRDLEPRLRALG", "output": "Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone."}]}
+{"id": "function_test_3359", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAAELIKEYVPIVSEYAPGLIEGLLSWKGAVGLVAATGIGYVLIIQRLQNTSATKNLWGLTGGGVQAKDVSKVADVYDKSYGKEGDGSLTLHHLDKKESVAVVDTFYNLVTDGYEACWDTSFHFSPRPRFTNFRTAQILHEARIGYMARIQPGFKVLDCGCGIGNPGRTVAALTGAHVTGITINEYQVKRALYHTKKAGLTGLFTPVQGDFTDMPFADKTFDAAFAIEATCHAPKLEQVYGEIFRVLKPGAFFAVYEAVTTDKFDPANKRHVEIINSLVYGNGIPDMRTWKQAEEAGKNVGFKLCCAFDAGAASPVALPWWERVKDMINWGVVKYTKAACLALDSLRLLPKDYWKVANMVGDSLPDLVESGETGIFTPMYLLVWQKPEE", "output": "Unable to convert squalene, botryococcene, cycloartenol, zymosterol or lanosterol to mono-, di-, tri- or tetramethylated derivatives."}]}
+{"id": "function_test_3360", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIGIDIVSIARIEKCVKRFKMKFLERFLSPSEIVLCKDKSSSIAGFFALKEACSKALQVGIGKELSFLDIKISKSPKNAPLITLSKEKMDYFNIQSLSASISHDAGFAIAVVVVSSSNE", "output": "Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein."}]}
+{"id": "function_test_3361", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIMVQGEVSGKKYTEPFSKGVLARSLTRAEMDPNRAYTFASRIEAHLKKNKVDLITIEELVEIVSEHLRKEDPEVAEKYMLWRKIRQCKEPLIILIGGASGVGTSSIAFEVANRLGIRNMISTDMIREVMRKIVSRELLPSIYESSYTAYQSLRIPPPPELDEVLIGFRDHVESVSIGVEAVIERALTEGISIVIEGVHIVPGFIREDLVNKENVAMFVLTVSDENVHKGRFYSRCRQMWARRPLKRYISYFWAIRRIHRYIENQARKHGVPVIENIDVVTTIDSIIKSLTKTTVKGGEKGAEKTE", "output": "Catalyzes the phosphorylation of 2-phosphoglycerate to 2,3-diphosphoglycerate. Involved in the biosynthesis of cyclic 2,3-bisphosphoglycerate, a thermoprotectant."}]}
+{"id": "function_test_3362", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MATFKDACFHYRKITKINRELLKIGANSIWTPVRSDKIKGWCIECCQLTELVFCSGCSLAHVCQWCVRNKRCFLDSQPHLLKLRTFEAPITKEKLQCVISMYNMLFPINENIINRFKKNVKQKKCRNEFNATWYNQLLLPITLNAAVFKFQSRIVYVFGFYEGTTACGYLPYRMVNCIDIYDRLLLDSVNFDRMSALPSDLQALYAQKYFKISRLPSMKLRQVYYSDFTKQNLITKYRTKTRITHRNVSKINWDTDIELHNDLMHNKHRILTALTTAEEKQFEVHDVNLGRIKADMFELGHHCKPNYISSNHWQPASRVSLCRWCNIKYAFRNMDWRMESMYNELMSFIQSCYKSNANVDHCSSIESVYPMVRNVFWHSTTKYIDETLEKLFNMMNPVNIDNQKVISFHWQIDLSLYLHIKMILKTEALPFMLKVHEFQSIVKGIINQWCDFSKVSELPICVESTDTLLRMYEQGELSEEYELLISDSDGDE", "output": "Plays a role in the inhibition of host innate immunity by inducing the degradation of key host factors required to activate interferon production such as IRF3, IRF5 or IRF7. Associates with components of cullin RING ligases (CRLs) including CUL1 or CUL3, which are essential multisubunit ubiquitination complexes, to modulate their activities."}]}
+{"id": "function_test_3363", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKKVNVVAIGGGTGLSSLLRGLKIEVGRSIGRLSAIVTVADSGGSTGRLRKIYNIPAPGDIRNCIVALSDAEELMQKLFQYRFKGDGLEGHAFGNLFLTALTDITGSFLKAIKETSKILKTKGDIIPSTYENVNLVAEFDDGKVIKGEEEITEYGKKGHKVVNIWLEPKNPKAPEEAIERIKEADLIIIGPGSLFTSILPNFLVPQIREAVKESRALKVFVVNVMTQPGETDNFTAWDHIDTFLKFSGIDLVDVAVVNTQMPSNGLLKKYLEQNQEPVTPDVGRIGREGITVYAENLIGESGDFVRHDPQKLTEVILKILENELLSKV", "output": "Required for morphogenesis under gluconeogenic growth conditions."}]}
+{"id": "function_test_3364", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIKMFKYKQVIVARADLKLSKGKLAAQVAHGAVTAAFEAYKKKREWFEAWFREGQKKVVVKVESEEELFKLKAEAEKLGLPNALIRDAGLTEIPPGTVTVLAVGPAPEEIVDKVTGNLKLL", "output": "The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis."}]}
+{"id": "function_test_3365", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSIPVMQLKHELALKAREEYLRKELPLKVRANTSRMNPGAKTWIPQINHRKSRNHYNRKETCQFPPLYNVEAKINHSYSAFYRPFTKRENGLWYANPYYMQHGPNGNYHHVYY", "output": "Has a role in meiosis."}]}
+{"id": "function_test_3366", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEEFQGYLELDRSQQHDFLYPLIFREYIYALAHDRGLNRSVLLDNVSYDKKSSLLIIKRLISRMYQQNHFIISVNDSNQNKFFGYNKNLYSQMISEGFAVIVEIPFSLRLVSSLEETETVKSYNLRSIHSIFPFFEDKFPHLNYASDVLIPYPIHLEILVQTLRYCVKDPSSLHLLRLFLHEYYNWNTLITPKKSIFAKSNQRLFLLLYNSYVCEYESILLFLRNQSNHLRLTSSGILFERIRFYEKIKYPVEEVFANDFPATLWFFKDPFIQYVRYQGKSILASKDTPLLMNKWKYYLVHFWQCHFYVWSQPGRIHINQLSKHSFDFLGYLSSIRPNISVVRSQLLENSFLMDNAMKKLDTLFPIIPMIGSLAKVKFCNTSGHPISKSSWADSSDSDIIDRFVRIGENLSHYYSGSSKKKSLYRIKYILRLSCVKTLARKHKSTVRTFLKRLGPKLLDEFFTEEEQIFSLLFPRTSSTLKRFYRGRIWYLDILCINDLVNHE", "output": "Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns."}]}
+{"id": "function_test_3367", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDILSLGWSALMVVFTFSLALVVWGRNGF", "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions."}]}
+{"id": "function_test_3368", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKIIHTAIEFAPVIKAGGLGDALYGLAKALAANHTTEVVIPLYPKLFTLPKEQDLCSIQKLSYFFAGEQEATAFSYFYEGIKVTLFKLDTQPELFENAETIYTSDDAFRFCAFSAAAASYIQKEGANIVHLHDWHTGLVAGLLKQQPCSQLQKIVLTLHNFGYRGYTTREILEASSLNEFYISQYQLFRDPQTCVLLKGALYCSDFVTTVSPTYAKEILEDYSDYEIHDAITARQHHLRGILNGIDTTIWGPETDPNLAKNYTKELFETPSIFFEAKAENKKALYERLGLSLEHSPCVCIISRIAEQKGPHFMKQAILHALENAYTLIIIGTCYGNQLHEEFANLQESLANSPDVRILLTYSDVLARQIFAAADMICIPSMFEPCGLTQMIGMRYGTVPLVRATGGLADTVANGINGFSFFNPHDFYEFRNMLSEAVTTYRTNHDKWQHIVRACLDFSSDLETAANKYLEIYKQ", "output": "Synthesizes alpha-1,4-glucan chains using ADP-glucose."}]}
+{"id": "function_test_3369", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNLATIASEIEVVKTNQKTIESKIDQILAKIGSTPDESSNLESVAAKIISDLTKEMKECHCNKEIVEILNKDKAIIPSPEQDSIQKRLSEPQYTFPNFDVGNEGMGSSTNPNALKWPPTEKPQPWPPR", "output": "Plays a role in virus cell-to-cell and plant-to-plant transmission. Interacts with virion icosahedral capsid and movement protein, thereby facilitating virion cell-to-cell transmission through plasmodesmata opened by viral movement protein. Also interacts with aphid transmission factor, attaching the virion to aphid stylet when the animal feeds on an virus infected plant. Aphid saliva may later detach the virion, inducing release of infectious particles when the animal feeds on a new plant (By similarity)."}]}
+{"id": "function_test_3370", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "DEPTTDLPICEQAFGDAGLCFGYMKLYSYNQETKNCEEFIYGGCQGNDNRFSTLAECEQKCIN", "output": "Inhibits chymotrypsin and thus avoids the accidental chymotrypsin-mediated activation of prophenoloxidase. This enzyme is required by the insect immune system to produce melanin which is used to engulf foreign objects."}]}
+{"id": "function_test_3371", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSLNITENESISTAVIDAINSGATLKDINAIPDDMMDDIYSYAYDFYNKGRIEEAEVFFRFLCIYDFYNVDYIMGLAAIYQIKEQFQQAADLYAVAFALGKNDYTPVFHTGQCQLRLKAPLKAKECFELVIQHSNDEKLKIKAQSYLDAIQDIKE", "output": "Assists the correct folding of nascent IpaB. Once it is bound to IpaB, it binds to IpaC and impedes their premature association that would lead to their degradation in the absence of IpcG (By similarity)."}]}
+{"id": "function_test_3372", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MANIKSAKKRAIQSEKARKHNASRRSMMRTFIKKVYAAIEAGDKAAAQKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA", "output": "Binds directly to 16S ribosomal RNA."}]}
+{"id": "function_test_3373", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDEYSPKRHDIAQLKFLCETLYHDCLANLEESNHGWVNDPTSAINLQLNELIEHIATFALNYKIKYNEDNKLIEQIDEYLDDTFMLFSSYGINMQDLQKWRKSGNRLFRCFVNATKENPASLSC", "output": "Attenuates Hha toxicity and regulates biofilm formation. Binds to various coding and intergenic regions of genomic DNA (By similarity)."}]}
+{"id": "function_test_3374", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKKVLGVILGGLLLLPVVSNAADAQKAADNKKPVNSWTCEDFLAVDESFQPTAVGFAEALNNKDKPEDAVLDVQGIATVTPAIVQACTQDKQANFKDKVKGEWDKIKKDM", "output": "Required for optimal acid stress protection. Exhibits a chaperone-like activity only at low pH by suppressing non-specifically the aggregation of denaturated periplasmic proteins."}]}
+{"id": "function_test_3375", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGIFSRFADIVNANINALLEKAEDPQKLVRLMIQEMEDTLVEVRSTSARALAEKKQLTRRIEQASAREVEWQEKAELALLKEREDLARAALIEKQKLTDLIKSLEHEVTLVDDTLARMKKEIGELENKLSETRARQQALMLRHQAANSSRDVRRQLDSGKLDEAMARFESFERRIDQMEAEAESHSFGKQKSLDDQFAELKADDAISEQLAQLKAKMKQDNQ", "output": "The phage shock protein (psp) operon (pspABCDE) may play a significant role in the competition for survival under nutrient- or energy-limited conditions. PspA negatively regulates expression of the pspABCDE promoter and of pspG through negative regulation of the psp-specific transcriptional activator PspF. Is also required for membrane integrity, efficient translocation and maintenance of the proton motive force (By similarity)."}]}
+{"id": "function_test_3376", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAYFLDFDERALKEWRKLGSTVREQLKKKLVEVLESPRIEANKLRGMPDCYKIKLRSSGYRLVYQVIDEKVVVFVISVGKRERSEVYSEAVKRIL", "output": "Toxic component of a type II toxin-antitoxin (TA) system. A sequence-specific, ribosome-dependent mRNA endoribonuclease that inhibits translation during amino acid starvation (the stringent response). Acts by cleaving mRNA with high codon specificity in the ribosomal A site between positions 2 and 3. Acts with RelB as a corepressor of relBE transcription (By similarity)."}]}
+{"id": "function_test_3377", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDPQNALYYQPRVPTAAPTSGGVPWSRVGEVAILSFVALICFYLLYLWVLRDLILVLKARQGRSTEELIFGGQAVDRSNPIPNIPAPPSQGNPGPFVPGTG", "output": "Involved in the viral transport within, and between cells."}]}
+{"id": "function_test_3378", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MADCITIAPELSFKDQITELAAHLSRSLPNADNQVAVKEFVQGYEAQVDTEEGRGDVEDAKKKQVVKSIVDKFVELKGGLEAAKESEVESSHFLLQHVLSTTFDQASEEYAQAVKDVNEAVKKGAQETTKITRAEAASRVLKNTYNFLPSNSPIRPSTLLSLMSLLASTLDLSALPLPTSTLLPALSSWSIPSSEKVSFLTTASGLYQSTGNLAKALELLTLALKESVEPTVVERAVLLALAVPNKFELDDVLAVQGVKEQLGKVQGVVELFEGDEVEAIEKGKKWTAENVSLIEGAGIPGFTSETVLRKLRLIALVALCTKSETRQLEYAPIAKALAIEESEVETWVIDAVRSKLIVARISQPQSLIRIHSISSITASSRRFGPSEWQLLEKRLEQWKKSVNEARQVVEEAETVAQQGLGQQRRGGKRREEKKEKEDKEEQE", "output": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation."}]}
+{"id": "function_test_3379", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKIAVAGSGYVGLSLGVLLSLQNEVTIVDILPSKVDKINNGLSPIQDEYIEYYLKSKQLSLQATLDSKAAYKEAELVIIATPTNYNSRINYFDTQHVETVIKEVLSVNSHATLIIKSTIPIGFITEMRQKFQTDRIIFSPEFLRESKALYDNLYPSRIIVSCEENDSPKVKADAEKFALLLKSAAKKNNVPVLIMGASEAEAVKLFANTYLALRVAYFNELDTYAESRKLNSHMVIQGISYDDRIGMHYNNPSFGYGGYCLPKDTKQLLANYNNIPQTLIEAIVSSNNVRKSYIAKQIINVLEEQESPVKVVGVYRLIMKSNSDNFRESAIKDVIDILKSKDIKIIIYEPMLNKLESEDQSVLVNDLENFKKQANIIVTNRYDNELQDVKNKVYSRDIFGRD", "output": "Catalyzes the formation of UDP-glucuronic acid which is required for capsular hyaluronic acid synthesis."}]}
+{"id": "function_test_3380", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "ADDDLEGFSEEDLKAIKEHRAGLAA", "output": "Unknown. Is not toxic to mammals."}]}
+{"id": "function_test_3381", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "TPEHQRYVELFIVVD", "output": "Snake venom metalloproteinase that impairs hemostasis in the envenomed animal."}]}
+{"id": "function_test_3382", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSRRLILILVLVAMLVKTMAGMESKWVETTYEIKKRSGTSEKERESERLLGVVNPLIKCFRSPCPGRRAISEQT", "output": "Possesses antimicrobial activity against both Gram-negative and Gram-positive bacteria, as well as against the fungus C.tropicalis. Also possesses a relatively high hemolytic activity."}]}
+{"id": "function_test_3383", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAK", "output": "Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Calcium-binding is required for the activation of calmodulin. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II (CaMK2), and phosphatases."}]}
+{"id": "function_test_3384", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDIINIAWAALMVIFTFSLSLVVWGRSGL", "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions."}]}
+{"id": "function_test_3385", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSGLLYALLIIPMIGIFFILSFDSYNFNITSNNSNSGSFSEAGAGKNSGGELLKVLVINNELNFYKKIAFITTIMNLIVSLIIYILFDFSTNQFQFVQDALELSVYNIYLGVDGLSIYFVLLTTIIMPIALISNWNSITHNIKAYLIIILLLETLLLAVFLVLDVLLFYIFFESILPPLFILIGLFGSSNKVRASFYIFLYTLLGSLFLLLSILTMSSLIGTTYLDVLSKSNFEYTTQIFLFLGVFIAFAVKTPTVFLNSWLLKAHVESPLGGSIVLAGIVLKLSLYGIFRLILPLLPKISLNYTSIIFSIGIITIIYASFSTLRTIDIKELIAYSSVSHAAVYLIGVFSNIIQGIEGGILLGLGHGFVSSGLFICAGGVLYDRSGTRIISYYRGTAQVMPLFSILFFILCLGNCGAPLTLNFVGEFMSLYGTFERLPLLGLFSSSSMIFSAAYTIYMYNRIAFGGSFSKFFEENIGDVTKREFFLLFTLIIFTIMFGIYPSFILDGLHYNVTSLLFGV", "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)."}]}
+{"id": "function_test_3386", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNLVTTIITITITLSAVLATISFWLPQISPDAEKLSPYECGFDPLGSARLPFSLRFFLIAILFLLFDLEIALLLPLPWGDQLNAPTLTLLWSTAVLALLTLGLIYEWTQGGLEWAE", "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)."}]}
+{"id": "function_test_3387", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSRLLRVYVDGPHGLGKTTAASALASERGDAIYLPEPMSYWSGAGEDDLVARVYTAQHRMDRGEIDAREAAGVVLGAQLTMSTPYVALNGLIAPHIGEEPSPGNATPPDLILIFDRHPIASLLCYPLARYLTRCLPIESVLSLIALIPPTPPGTNLILGTAPAEDHLSRLVARGRPGELPDARMLRAIRYVYALLANTVKYLQSGGSWRADLGSEPPRLPLAPPEIGDPNNPGGHNTLLALIHGAGATRGCAAMTSWTLDLLADRLRSMNMFTVDYSAPPEACVAQMRNLLPSMQCTVTPKPESHRAVADAALAFMREMSNCK", "output": "Catalyzes the transfer of the gamma-phospho group of ATP to thymidine to generate dTMP in the salvage pathway of pyrimidine synthesis. The dTMP serves as a substrate for DNA polymerase during viral DNA replication. Allows the virus to be reactivated and to grow in non-proliferative cells lacking a high concentration of phosphorylated nucleic acid precursors."}]}
+{"id": "function_test_3388", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKKSIFSKKLLVSFGSLVALASIPLIAISCGQTNTDKSQQPGSGSSTSGDQSGTTTGGHSGSGTSTSGGQSGTTSGSGTTTGEQTETAPKSPESGSQEATPKSPESGSQEATPKSPESGSQEAAPKSSESGSQEAAPKSSESGSQEAAPKSSESGSQKTT", "output": "Responsible for the antigenic diversity for host adaptation."}]}
+{"id": "function_test_3389", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MALVVKGKVNINEFIDLSKSEKLLPSMFTPVKSVMVSKVDKIMVHKNESLSEVNLLKGVKLIEGGYVWLVGLVVSGEWNLPDNCRGGVSVCMVDKRMERADEATLGSYYTAAAKKRFQFKVVPNYGITTKDAKKNIWQVLVNIKNVKMSAGYCPLSLEFVSVCIVYKNNIKLGLREKVTSVKDGGPMELSEEVVDEFMENVPMSVRLAKFRTKPSKRGPKNNNNLGKGRSGGRPKPKSFDEVEKEFDNLIEDEAETSVADSDSY", "output": "Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding. The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier. Forms a ribonucleoprotein complex with viral RNA. Binds microtubules and modulates microtubule stability. Can bind double-stranded DNA. Triggers host hypersensitive defense reaction in incompatible plants harboring resistance (R) proteins."}]}
+{"id": "function_test_3390", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTDAFQKLFQQMLQSGQEMARAFNPALEHFDMRAMEKLVPTIPADMLEMWFGKTFNREGLDAKTRLLLTIGAITVQGALAEPQLRMTVRQALAAGATKREIAETIFQMSMFGGLPAMQKALEIAQSVYAEEDEE", "output": "May have a role in the regulation of NDH-1 biosynthesis."}]}
+{"id": "function_test_3391", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDVEVKKNKNEPYLKDHEVKDLIKRSQQGDQIARDTIVQKNMRLVWSVVQRFINRGYEPDDLFQIGCIGLLKSVDKFDLSYDVKFSTYAVPMIIGEIQRFIRDDGTVKVSRSLKEMSNKIRKAKDELSKLLGRVPTVAEVAEHLDLTPEEVVLAQEANRAPSSIHETVYENDGDPITLLDQIADHTEAKWFDKIALKEAIEELDEREKLIVYLRYYKDQTQSEVAARLGISQVQVSRLEKKILKQMKLHMNDT", "output": "Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. It is responsible for directing gene expression in the forespore compartment of developing cells of Bacillus."}]}
+{"id": "function_test_3392", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKKIEAIIRPFKLNEVKLALVKGGIGGMTVVKVSGFGRQKGQTERYKGSEYSIDIIDKIKIEIIVSDDKVNSITEIIIKTAKTGEIGDGKIFISDVEQVIRIRTNDLNSAAL", "output": "P-II indirectly controls the transcription of the glutamine synthetase gene (glnA). P-II prevents NR-II-catalyzed conversion of NR-I to NR-I-phosphate, the transcriptional activator of glnA. When P-II is uridylylated to P-II-UMP, these events are reversed. When the ratio of Gln to 2-ketoglutarate decreases, P-II is uridylylated to P-II-UMP, which causes the deadenylation of glutamine synthetase, so activating the enzyme (By similarity)."}]}
+{"id": "function_test_3393", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSGDKKSRSVIYKKTSRDKAVSVYLGKRDYVDHIESVDPVDGVVFVDPDLLKGKKVYVTLTCAFRYGNEDIDVIGLTFRKDLFFARIQVYPPVEDVKCLTKVQERLMKKLGNNAYPFVMAFPDYLPCSVSLQPAMSDVNKACGVDFEIKAFSASNLEDRYHKKNSVRLLIRKIQYAPDQPGPTPRAETSWQFFMSDKPLHLTASLAKEVFYHGETITVAVTVTNNSEKTVKKISTSVEQTANVVLYSSDFYTKTVAFDESDEKVSPKSTYKHTFTLLPLLAYNREKREIALDGKLKHEDTNLASSTLLKEGIDRTVMGILVDYKIKVTLTVSGLLGDMTSSEVSTELPFILMHPKPDSGAKESEQEEDFVFEDFARDHLKDELQPEEKEEEEEDEK", "output": "Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase."}]}
+{"id": "function_test_3394", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNVAGLHTNAIYGFQLMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDHMGIRHYDLAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVAEFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEGIYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGKFYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNLVGFVWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAFDIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKLAVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENELVIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLAPIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIHTSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTYFERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQGSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEAIQLSVPLIADENEGATWYEAK", "output": "In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity."}]}
+{"id": "function_test_3395", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MHKKLTKEVDYMDAVLYVCHGSRVKEGADQAVAFIERCKKNLDVPIQEVCFLELASPTIEQGFEACIEQGATRIAIVPLLLLTAAHAKHDIPEEIQKVYERYPQVEVLYGEPFGVDERIVDILVERINETNVDKHEDSMVLLVGRGSSDPAVKRDLNEIAQLLKGKGAFKEVSTCYLAAASPNLKEGLHLAKRTSYKQVFVLPYLLFTGILMNEIKEELEQLSTDAQQFILANYLGYHDGLAHILSHQVKTLLSSKGNQYDVYRYA", "output": "Chelates iron to the siroheme precursor."}]}
+{"id": "function_test_3396", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLPHGLIVSCQALADEPLHSSFIMSKMALAAYEGGAVGIRANTKEDILAIKETVDLPVIGIVKRDYDHSDVFITATSKEVDELIESQCEVIALDATLQQRPKETLDELVSYIRTHAPNVEIMADIATVEEAKNAARLGFDYIGTTLHGYTSYTQGQLLYQNDFQFLKDVLQSVDAKVIAEGNVITPDMYKRVMDLGVHCSVVGGAITRPKEITKRFVQVMED", "output": "Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)."}]}
+{"id": "function_test_3397", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEVAYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVAKINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGKITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQGVGIKVDVNSL", "output": "Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.; "}]}
+{"id": "function_test_3398", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDSKETILIEIIPKIKAYLLDANISPKSYDDFISRNKNIFVINLYNVSTITEEDIRLLYTTIEQNIDADDQTLVAIFSYIGYKFEQAVKEEISTSLSFNDKNTTDEMTYNLYDLFFNTLDMYLRQKKISILVNDDVRGDVIVSYKNSDLVSSFNAELEPEIKKIPFNMKNLLPYLEKNLDQLRFSKKYLDFAYLCRHIGIPISKKKYNVRYVFLYKIDGLSIPIIIKDFLDVKYVYLENTGKIYKNSFSEDHNNSLSDWGKVIIPLLKDRHLYSYIFLSSYHLHSYYTDLIARDEPVFVKRKKLDIIEIDEPEAWKRDVRVEFAPCEHQIRLKEAMKVDANYFTKINNFANEFIYYEDGVAYCRVCGINIPIFNLDAADVIKNTVIVSTFNKTIFLSEPYSYFVHSQRFIFNIIMSFDNIMKSQTWVMKYNINRLILNFLIDINSRRQEYEKKFSSEIKRGLFFLRLSANLFESQVSSTELFYVSKMLNLNYIVALVIILNSSADFIVSYMTSKNKTVEESTLKYAISVVIYDFLVKTRICEKGSLDTIVLFTDVYTSIMPEELDLHFQRITLELRKLVSIQRSALEPNYDVESRGEELPLSALKFFDTSTIIVKTMAPVHTCVEQKIVAPTPSVEPTDASLKNFKELTCDEDIKILIRVHDTNATKLVIFPSHLKIEIERKKLIIPLKSLYITNTLKYYYSNSYLYVFRFGDPMPFEEELIDHEHVQYKINCYNILRYHLLPDSDVFVYFSNSLNREALEYAFYIFLSKYVNVKQWIDENITRIKELYMINFNN", "output": "DNA-directed RNA polymerase-associated factor required for the transcription of viral early genes as well as for transcription termination. Within minutes after virus entry, recruits the core RNA polymerase, the early transcription factor (ETF) and other enzymes needed for transcription initiation, elongation, and termination thereby allowing synthesis of early mRNAs which are extruded through pores in the core particle. Recruits the multifunctional OPG102 protein, with poly(A) polymerase-stimulatory, cap nucleoside-2'-O-methyltransferase, and transcription elongation activities. Interacts with nucleoside triphosphatase I/OPG123, a DNA-dependent ATPase required for the termination of early transcripts. Acts as a transcription termination factor by binding, together with the capping enzyme/VTF, to the termination motif 5'-UUUUUNU-3' in the nascent mRNA. Involved as well in the packaging of RNA polymerase and other components needed for early transcription in assembling virus particles."}]}
+{"id": "function_test_3399", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGIQHEFDIIINGDIALRNLQLHKGDNYGCKLKIISNDYKKLKFRFIIRPDWSEIDEVKGLTVFANNYAVKVNKVDDTFYYVIYEAVIHLYNKKTEILIYSDDENELFKHYYPYISLNMISKKYKVKEENYSSPYIEHPLIPYRDYESMD", "output": "Inhibits antiviral activity induced by type I interferons. Does not block signal transduction of IFN, but is important to counteract the host antiviral state induced by a pre-treatment with IFN (By similarity)."}]}
+{"id": "function_test_3400", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAYNPITPSKLIAFSASYVPVRTLLNFLVASQGTAFQTQAGRDSFRESLSALPSSVVDINSRFPDAGFYAFLNGPVLRPIFVSLLSSTDTRNRVIEVVDPSNPTTAESLNAVKRTDDASTAARAEIDNLIESISKGFDVYDRASFEAAFSVVWSEATTSKA", "output": "Capsid protein self-assembles to form rod-shaped virions about 18 nm in diameter with a central canal enclosing the viral genomic RNA."}]}
+{"id": "function_test_3401", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "VMNLWPGVRLRVTEGWDEDGHHSEESLHYEGRAVDITASDRDRNKYAMLARLAVEAGF", "output": "Intercellular signal essential for a variety of patterning events during development."}]}
+{"id": "function_test_3402", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "VHMARNMXVPPXXAD", "output": "Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone."}]}
+{"id": "function_test_3403", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "DAHNEDEEHAEGS", "output": "Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of size variants of the capsid proteins, which differ in the N-terminushe capsid encapsulates the genomic ssDNA. Capsid proteins are responsible for the attachment to host cell receptors. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis (By similarity)."}]}
+{"id": "function_test_3404", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "AVNVNTNVSAMTAQRYLNQA", "output": "Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella."}]}
+{"id": "function_test_3405", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "QVNFSPGWGT", "output": "Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects)."}]}
+{"id": "function_test_3406", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "QVNFSPGWGT", "output": "Hypertrehalosaemic factors are neuropeptides that elevate the level of trehalose in the hemolymph (trehalose is the major carbohydrate in the hemolymph of insects)."}]}
+{"id": "function_test_3407", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIVLDASAAVELMLTTPAGAAVARRLRGETVHAPAHFDVEVIGAIRQAVVRQLISDHEGLVVVVNFLSLPVRRWPLKPFTQRAYQLRSTHTVADGAYVALAEGLGVPLITCDGRLAQSHGHNAEIELVA", "output": "Toxic component of a type II toxin-antitoxin (TA) system. An RNase. The cognate antitoxin is VapB12 (By similarity)."}]}
+{"id": "function_test_3408", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSDNAKHHRDGHLVASGLQDRAARTPQHEGFLGPDRPWHLSFSLLLAGSFVLFSWWAFDYAGSGANKVILVLATVVGMFMAFNVGGNDVANSFGTSVGAGTLTMKQALLVAAIFEVSGAVIAGGDVTETIRSGIVDLSGVSVDPRDFMNIMLSALSAAALWLLFANRMGYPVSTTHSIIGGIVGAAIALGMVSGQGGAALRMVQWDQIGQIVVSWVLSPVLGGLVSYLLYGVIKRHILLYNEQAERRLTEIKKERIAHRERHKAAFDRLTEIQQIAYTGALARDAVAANRKDFDPDELESDYYRELHEIDAKTSSVDAFRALQNWVPLVAAAGSMIIVAMLLFKGFKHMHLGLTTMNNYFIIAMVGAAVWMATFIFAKTLRGESLSRSTFLMFSWMQVFTASGFAFSHGSNDIANAIGPFAAILDVLRTGAIEGNAAVPAAAMVTFGVALCAGLWFIGRRVIATVGHNLTTMHPASGFAAELSAAGVVMGATVLGLPVSSTHILIGAVLGVGIVNRSTNWGLMKPIVLAWVITLPSAAILASVGLVALRAIF", "output": "Potential transporter for phosphate."}]}
+{"id": "function_test_3409", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKSVITTTISAADAAGRYPSTSDLQSVQGNIQRAAARLEAAEKLGSNHEAVVKEAGDACFSKYGYLKNPGEAGENQEKINKCYRDIDHYMRLINYTLVVGGTGPLDEWGIAGAREVYRTLNLPSAAYIAAFVFTRDRLCIPRDMSAQAGVEFCTALDYLINSLS", "output": "Light-harvesting photosynthetic bile pigment-protein from the phycobiliprotein complex."}]}
+{"id": "function_test_3410", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVLTDPIADYLTRIRNANMVRHESLVVPASKMKKDISEILKREGFIRDYEVIDDDKQGVIRIFLKYGKNNERVISGLKRISKPGLRSYVKSDAVPKVLNGLGIAIISTSEGVITDKEARAKNVGGEVLAYVW", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit."}]}
+{"id": "function_test_3411", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRNISLTTTIITTTDTTGNGAG", "output": "This protein is involved in control of the biosynthesis of threonine."}]}
+{"id": "function_test_3412", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGVTKKPDLNDPVLRAKLAKGMGHNYYGEPAWPNDLLYIFPVVILGTIACNGGLAVLEPSMIGEPADPFATPLEILPEWYFFPVFQILRTVPNKLLGVLLMVSVPAGLLTVPFLENVNKFQNPFRRPVATTVFLVGTLVALWLGIGATLPIEKSLTLGLFSIK", "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions."}]}
+{"id": "function_test_3413", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTELEKIGLIPRSIVRMLDRFYYQIYLGTAEPLVKQFRFSKYLLLTSVKSLFVVLFIPFFINIFTKIYVFRPLVEYFWDRKQTEIFLNYELQEKAFSEIRNFEEKMYFDYLIKTENFFPEKPKYFLPEAPLPGELPMQKKELFGVNLQEYKFKSNHSCLKFYSTEANSSVFGFENGNSLKLSHVSLFASKYPIKFTVIKNDLFKIKNQEGKSGAFPASEEEKKLKKGEKALLFPLLPTFSFSPRKNSSFFLGEKENMGISPGSKEEKKLKFFFFPHSGGTFSHCSLGIEDSEGKFSPGRREISPLLPGEHCGKLGKNAIFLLEEEKNGSGETRASFATSGSKAPALEELKNQSIDFLIPLEKSSPQRTFFSQHLASDFCSFDLTAQTKFHFVSFPNSIDTVPYNFNKNTESIFRQKTRELANHYNNESISAITNLLADFMGLFILLFLLVNMKMSLMNTTAFLSESFFSLKDSKKAFLMLLFTDLLVGFHSPRGWEVIFHFLFEHFGLPENHNIIFLLVGTFPVLLDALFKYWIFRHLNRHSPATVATFQAMVE", "output": "May be involved in proton extrusion. Indirectly promotes efficient inorganic carbon uptake into chloroplasts."}]}
+{"id": "function_test_3414", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MARRPKGRFIDGIVLLDKDTGMSSNFALQRVKRFFNANKAGHTGALDPLATGMLPICLGEATKFSQHLLDSDKRYLVTAKLGQRTDTSDSDGEVVQTRPVNVTQALLDEKLAFFRGTTQQIPSMYSALKYQGQPLYKYAREGIEVPRESRPITVFELNFIKLEGDELTLDIHCSKGTYIRTIIDDLGEMLGCGAHVVMLRRTQVAEYPYEKMVTLAQLEALLEQAHRQDVAPQTLMDPLLLPMDTAVAKFAEINLPEAMLYYVMQGQAIQAAGLKPDELVRITIGDERRFVGMGIMNDDGLLAPKRLIVIHDNDAAE", "output": "Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs."}]}
+{"id": "function_test_3415", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRIRLISVGGRMPGWAAEGYREYAQRLGGGISLELVEIPLGRRGKGADPRRALDEEGRRMLKALGDEQVVALDVRGKAWDTPALARELDGWLHDGRDLALLVGGPDGLHPDCLARAERRWSLSPLTFPHMLVRVLLAEQLYRAWSLLQGHPYHRA", "output": "Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA."}]}
+{"id": "function_test_3416", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVVLGRVIGPHGIRGQIKVTPFTEHIDGLMEYPVWWLSNDEKSWQIVHPTSFSVHDSLLIITLEEYSDRTNASGLKGWLIAVPRSQLPQLSEDGKEGYYWSDLIGISVVNTQGEFIGTVAGLFETGANDVLRIQLPGGKEELIPFVDQVVRQVDMRSRQIMVDWELDY", "output": "An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes."}]}
+{"id": "function_test_3417", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAEERGEKRGRRRDRENPRDRDDESSELVDKLVGINRVAKTVKGGKNFGFAALVVVGDQKGRAGFGKGKAREVPEAIRKATEEAKRNLVRIPLREGRTLHHDGNGRHGAGKVVLRAAPPGTGVIAGGPMRAVMEVLGVQDVVGKSLGSSNPYNMVRATFDALKGQANPRTVASKRGLKVQDIVGRRTDGASEAGMADSVN", "output": "With S4 and S12 plays an important role in translational accuracy.; "}]}
+{"id": "function_test_3418", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MISGSDLRKGTTFELDGQVYTVIDFLHVKPGKGAAFVRTKLRNVIMGGVTDRTFNPTDKLQEAIIERKEMQYLYSDGELYYFMDQETFEQIPLNHEKVEDAIKFLKENMNAVIKFYKGEAFSVEAPNFVELLITECEPSVKGNTATTAMKTAVVETGATVMVPMFVEEGNTIRIDTRTGEYMERV", "output": "Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase."}]}
+{"id": "function_test_3419", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEAIKGSDVNVPDAVFAWMLDGRGGVKPLENTDVIDEAHPCWLHLNYVHHDSAQWLATTPLLPNNVRDALAGESTRPRVSRFGEGTLITLRCINGSTDERPDQLVAMRVYMDGRLIVSTRQRKVLALDDVVSDLEEGTGPTDCGGWLVDVCDALTDHSSEFIEQLHDKIIDLEDNLLDQQIPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPWMSDDQRRRMQDIADRLGRGLDEIDACIARTGVMADEIAQVMQENLARRTYTMSLMAMVFLPSTFLTGLFGVNLGGIPGGGWQFGFSIFCILLVVLIGGVALWLYRSKWL", "output": "Zinc transporter. Acts as a Zn(2+):proton symporter, which likely mediates zinc ion uptake."}]}
+{"id": "function_test_3420", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKPSIVAKLEALHERHEEVQALLGDAQTIADQERFRALSREYAQLSDVSRCFTDWQQVQEDIETAQMMLDDPEMREMAQDELREAKEKSEQLEQQLQVLLLPKDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSASEGEHGGYKEIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPDAELPDINPADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGARIHAAEMAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVMEGKLDMLIEPIIQEHQADQLAALSEQE", "output": "Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA."}]}
+{"id": "function_test_3421", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKLHTLRPAKGSVKTSKRIGRGTGSGRGGTSTKGHKGAKSRSGYSSKIGFEGGQMPLQRRLPKFGFKPLNKIEFKPINLDELLELIEKTGASVIDTALMNQNGLIGKNDKVKVLARGEVKSIKAEIIAHAFSASASEAITNAGGKVTLIG", "output": "Binds to the 23S rRNA."}]}
+{"id": "function_test_3422", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDKTIWIKADKGHWEAHKDRITTGLESGANCVLVNSDEVEKVRELGDIQVAAFTYDDKSGADIVVVGKGGEGDGTKPLSPDPVGSLDMITAIRLKEKGLTVGAYVVIQNKKYEEFAAEIGKECDFLIIVGTDWKVIPLENLIAALQDSDVKIIAGVRDQDEAKLALETMEHGSEGVLLDSDDPNTIKATVAVAERSGIEDLKLVPGKVTKVEAVGMGDRVCVDTCNMMTKGEGMLVGSQASGMFLVHSESEESPYVASRPFRVNAGAVHAYVKVGDRTRYLSELSSGDEVTIVNAGGKQRTGIVGRVKIERRPLMLVEAEVNGEIIKNILQNAETIKLVDINGEPISVADLKPGNEVMVYYEGGARHFGMKVEETIIEK", "output": "Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis."}]}
+{"id": "function_test_3423", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFMKTDDFDYKLPEELIASYPLENRDASRLLKLNKQTGEIADYKFTDFIDFINPGDLLVFNNSKVMLARLYGSKTTGAKLEYLIERIKTPKLFETHIKANRSPAIGSEIYVEDTLAKVLDKDGGMYLLEIQGDKDIYQLMEEFGHIPLPPYMKRDDEEFDAERYQTVYAQDLGSVAAPTAGLHFSKELMQQIKDKGVDIAYITLHVGSGTFKPVQVDDVESHKMHAEVISVPVEVCQKIRQTKENGGRVIAIGTTSVRSLETAGQNGQIEPYQGETDIFLYPGKKFNVVDAMITNFHLPKSTLIMLVSAFADKEKIIKAYEHAIAERYRFFSYGDAMFIF", "output": "Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)."}]}
+{"id": "function_test_3424", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTRVKRGYVARKRRKRVLQLTQGFRGAHSVLFRTANQQNIKALRYASRDRARRKRDFRRLWITRINAGARKQGLSYSQLMHRFKKCGILINRKVLAQLALLDTKTFNQLVFYTDL", "output": "Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit."}]}
+{"id": "function_test_3425", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MASYYSNDFRPGLKIMFEGEPYAVESSEFVKPGKGQAFARVKMRRLLTGGRVEKTFKSTDSLEGADVNDMNLTYLYNDGEFWHFMNNETYEQLQADAKAVGDNGKWLIDQAECIVTLWNGQPIAVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGAVVKVPLFVQVGEIIKVDTRSGEYVSRVK", "output": "Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation."}]}
+{"id": "function_test_3426", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTTINVEVRNDQGKGASRRLRAANKFPAIVYGGSEAAISIALDHDTTKNLELKPGFYDSVLTLVIDGKETKVKVQAVQRHAFKPKLTHIDFVRV", "output": "This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance."}]}
+{"id": "function_test_3427", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSLSEARFHDLVDATQQALEDLFDESDLDLDMENSAGVLTVKFDNGSQLIFSRQEPLRQLWLADRSGGFHFDYDEESGKWVCEKTEELLGEMLERIVWERAGEKLDFDEI", "output": "Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis."}]}
+{"id": "function_test_3428", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPEDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIIFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRSSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLAKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKDRAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN", "output": "Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate."}]}
+{"id": "function_test_3429", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSFTTKVKEELIHLSTGDNNELAAIIKLSGSLGLAHQSLHLSITTENAKIARYIYSLIEDAYVIVPEIRYHQKTNLRKNRVYTVYVEQGVETILADLKLADSFFGLETGIEPQVLSDDNAGRSYLKGAFLAAGSIRDPESGKYQLEIYSVYLDHAQDLAQLMQKFMLDAKTIEHKSGAVTYVQKAEDIMDFLIIIGAMSCKEDFEAIKLLREARNDINRANNAETANIAKTISASMKTINNIIKIMDTIGLESLPIELQQVAQLRVKHPDYSIQQVADALEFPITKSGVNHRLRKINKIADDL", "output": "Involved in cell division and chromosome segregation."}]}
+{"id": "function_test_3430", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIQEQTMLTVADNSGARRVMCIKVLGGSCRRYASIGDVIKITIKEAIPRGKVKKGDVLKAVIVRTKKGVRRPDGSIVRFDGNACVLLNNNEQPIGTRVFGPITRELRIEKFMKIISLAPEVL", "output": "Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome."}]}
+{"id": "function_test_3431", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MALTLEQKQQVVAEVSEVAANAYSAVAAEYHGIGVAKLTKLREQAREKGVVLKVVKNTLAKRAFEGTKFESMSDRMTGPLLLAFSMEDLGSAARVIFDFSKDHKALETKLVSVGGVVYGPEELERVSKLPTRDEAISILMATMNAPVTKLVQTMNAVPGKFVRTVAAIKDAKEAA", "output": "Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors."}]}
+{"id": "function_test_3432", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAKLDAHDIIRTIAESKKKTPVKVYVKGDLNSLDVPSNVETYFTDNVGVMFGDWADVEPILKDSSVESYHLENDGRNTGVAMVDKKKFNARIEPGAIIRDQVEIGDNAVVMMGAVINIGAEIGEGSMIDMGAVLGGRAIVGKNCHIGAGTVLAGVVEPPSAQPVVIEDDVLIGANAVVLEGVRVGKGAVVGAGAVVTKDVEPYTVVMGMPAKKVKDVSQVDDSKTEIVDDLRKL", "output": "Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate."}]}
+{"id": "function_test_3433", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNNNFTKYLSTAPVIGVLWMTFTAGFIIELNRFFPDVLYFYL", "output": "May help in the organization of the PsaE and PsaF subunits."}]}
+{"id": "function_test_3434", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIEKVPMTAGGYAALEVELKQRQSVDRPRIIEHIAEARSHGDLSENAEYHAAKEEQSHNEGRIAELEDKLARADIIDISKLSGDTIKFGATVTLIDEDTEKKAVWQIVGEPEADAKKGRISITSPLARALIGKKKGASVEVVAPGGAKAYEITKVEWR", "output": "Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides."}]}
+{"id": "function_test_3435", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAVIKMKPTSPGRRGVVKISRDHLYKGEPFAPLLEPQFQHAGRNNNGHITTRHKGGGHKHHYRVVDFLRTKDGIPAKVERIEYDPNRSAHIALVCYADGERRYIIAPRGLEVGASIMSGAEAPIRVGNTLPIRNIPVGSIVHCIELQIGKGAQIVRSAGTSATLLAREGIYAQVRMRSGEVRKIHIECRATLGQVANEEHSLRRLGKAGAKRWKGIRPTVRGVVMNPVDHPHGGGEGKTGEGRHPVDPWGNLTKGYRTRNNKRTQVMIVSRRKK", "output": "One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome."}]}
+{"id": "function_test_3436", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSLNRSEKEAVISDVTGLAAKAQTLVMAEYRGITVADMTKLRSTARSNGVSLSVLKNTLARRAVTGSGFEIVSDLMTGPLIYGFSEDAVAAARVVADFAKTNVKLVIRGGAYGGKALDVNGVKQLASIPSKEVLLAQLLGLMQSPISRTARVLAAIAEKKGAGVADAPVEAAAEAVAA", "output": "Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors."}]}
+{"id": "function_test_3437", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSAAGDAGAGAANGSNNVAVVQATVSVSGNISVGDGSPNNNNNNNANGNTNGNSNNNGSTAGSSKGQLPLTPRFTAEEKDVLYTLFHLHEEVIDIKHRKKQRNKYSVRDTWDKIVRDFNSHPHVSAMRNIKQIQKFWLNSRLRKQYPYRDGSASGGSAGLGKVGTVSASAQQQQQQQQQQQQQQQQQHHDSVKVEPEYQISPEASEHNPQGEPFDEIEMDGNDVSEMEDDPLEAQQQQQQQQQQQQQAAAQAQAEAQQQQQQQSAVAEMQKLQVSAAVAAANASMLNTHRINVDSISAEKLTLNDLLHFKPARHDEIILQIKHPTDATATQIHTIPAQPQQHTMATITAGGYNQQIISEIKPQQITLAQYQAQQHQQAQARLRPGQAQQLAQQQLAAQQQQLAVAAAAAHQQQNSSSAAAVVVQQHQQQQQQQQHQQQQQQQQVQQQQQQQQQAAAAAAAVKMQLTGGTPTFTFSALPTVTAATSVPVTVPVPVTVPVTAAPAAVSNVSVSGAGTLPTGAQQQLQLQQQQQQQQQQQQQQQQAGDSYEERINYFKVKEAELRCKEQQLATEAKKIELNKAQDELKYMREVHRLRVEELKMKIRILQKEEEQLQKCSST", "output": "Involved in transvection phenomena (= synapsis-dependent gene expression), where the synaptic pairing of chromosomes carrying genes with which zeste interacts influences the expression of these genes. Zeste binds to DNA and stimulates transcription from a nearby promoter (By similarity)."}]}
+{"id": "function_test_3438", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVRIRIRAIGKIKESFIRDAIADYAKRMCSFCQVECIEYPEAPVPDTHPSTIEMACVSEGEKLCSGIDSLDYVIILDRTGKQVSSEGLAEVIRRCEIEGPYQLVFIIGGPHGLSKDCLQKGNIILSLSAMTFPHQIARLLLYEQLYRAFTIIRGLPYHR", "output": "Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA."}]}
+{"id": "function_test_3439", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPPKKEPVISAFERKRLENIANNNAILSGISTTAEKIIPKPAPPKPKRASAPRAKREPVKRETARPTRQSSRLAGLDADADTLKRKAEVEAEVEAEKAKAKKMRVSGDLSLGDIQVEGRKWENGLDGLAGLKGLSARGAQPGIRTFTDEDVKGTTDKGLKDLRLRMSGLKLYEKWPVQGAYPKLVPQRVYSLGFHPTESKPIIFAGDKEGAMGVFDASQEPVKAEDDDDDEEAEIPDPIISAFKTHSRTITSFHFSPVDANAVYSASYDSSIRKLDLDKGVSTEAFAPADADEDLPISAIDMPTSDPNMIIFSTLQGTLGRHDLRTKSSTAEIWGLTDQKIGGFSLHPAQPHLVATASLDRTLKIWDLRKIQGKGDARAPALLGTHDSRLSVSHASWSSAGHVATSSYDDRIKIYNFPDADKWTAGAALTEAQMEPARQIPHNNQTGRWVTILKPQWQRSPRDGLQKFVIGNMNRFVDVFAADGEQLAQLGGDGITAVPAVAHFHPTMDWVAGGNGSGKLCLWM", "output": "DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes."}]}
+{"id": "function_test_3440", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSDARIVAVGVEEEFHILDLTTRQLVPRAEEVLRRLDGDSFSPELLKSVVETNSQPTADLLELRTNLLDLRRRLAEVTGELGLGPAAAGTVPIVDMDLLDVSRDDRYEQMTEDYQIVAREQLICGAQVHVDVADRDLAMAVVAWTAPWLPMLLALSASSPFWMGADSGYASMRTLVWQRWPTAGVAGSFRTAAEYDQLVADLIKSGVISDPGMVYFDVRPSAHLPTVELRICDACPDVDNVILIAGLFRALVCQAIEEIEAGGQAPPPRAELLRAATWRAARSGLEGDLVDILGAGPIPAQAMLRRLLTEVRPQLERFDDWELIDNLAEQAVGRGSSAHRQRRAFARRGLLTDVADLVLAETRDVPPAGAAAALGSAPAVSASDQIAPRLLERYQPTGYDEIVDARGAVRPQYRAVMRTLERLGPGILDERVGTREAEQNDRGIVFRASGDSASRPFPFDLVPRIIAADDWTTLTTGLSQRVRALEAFLHDIYGERAAVADGIVPAWVVNDAPSLRHGGRAVGPDAIRVTVAGIDLVRGGDGGWLVLEDNLRVPSGIAYAMEGRRLAESVLPELGPPAGILRLDGIPALLHEALVAAAPAAATGDPAVAVLTGGKTDAAYFEHSLLAEKMGVALVEPADLLVDDNDVVYRIDGSRRCRVDVLYRRMDEDDLFGALGAAGTPLGLPLLRAIRARRVGIANALGNGVGDDKVVYAYVPRMVTYYLGEQPVLDDVPTYVCGDPEQCEHVLDNLDQLVVKPVDGYGGSGVVIGPHAEPYRLTEVRERILANPRQWIGQELVSLSTHPTWHDSHLEPCAVDLRVFVYAGREPRVVPAALSRVAPPGSLIVNSSQGGGSKDTWIPRR", "output": "ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity."}]}
+{"id": "function_test_3441", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSEESHPHEGHMTPSKLFYLALGSVGVVYGDIGTSPLYAFREALKPIAHDGLTRFEVISLISLMIWALTIIVTIKYVLFLLRADNEGEGGTLSLLALLMKTANGHTAILMLLGLMGAALFLGDAMITPALSVLSAVEGLKLVTPSLSDYIVPISVVILALLFVVQSRGTGAVARFFGPITAVWFLVMAAAGISHISDDFGILAAFNPYYAVSFLLHEGFYGVVVLGAVFLTVTGAEALYADLGHFGRRPIQWAWFLLVFPALTLNYLGQGALVLGKPETMSDPFYLMYPKWALLPVVILATAATIIASQAVITGAFSMVRQGINLGFLPRMEILFTSETNTGQIFVPSVNAVLFIGVIFLVLSFKTSDALATAYGISVTGAMVVTSIMAFEFVRARWNWSLPLAVVALAPLVVLELIFLGANLLKIHDGGYIPILIATAFTVIMWTWRRGTAILMEKTRHTDIPLPSFVSAIERKSDHSPAQVPGTAIFLTSDPESAPAALLHNLKHNHVLHDRNVILTIRTANKPRVLNQDRFRIEQISERFFRVELLFGYMEAQNVSQALAVLRKAGLKFDIMSTSFYLGRQKVIPDTNSGMPYWQDRFFILLANGASLPSDYFHLPANRVVELGSQIIV", "output": "Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter."}]}
+{"id": "function_test_3442", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MANRIKKGDQVVINTGKDKGKQGEVVRVDGDRVIVSNANLIKRHTKPNPQAGVAGGVVEREASIHISNVNIVNPATGKGERVGFKVLEDGRKLRVFRSSGEALDA", "output": "One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.; "}]}
+{"id": "function_test_3443", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEMLQGLLLLMLLSMGGTWASKEPLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPTMTRVLQSVLPPLPQVVCTYRDVRFESIWLPGCPRGVDPVVSYAVALSCHCGLCRRSTSDCGGPKDHPLTCDHPQLPGLLFL", "output": "Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids."}]}
+{"id": "function_test_3444", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAQDCITIKGTRGGLLILLDASRDFNEIKANLAAKFAAARGFFRGAAFALVPTSPLNSQETAELEAICREHGLVPGNNITLPSRRRPGGNQAAHPDPVALTSTGLPTLLDEGNLRNGQEINYPGHVMWLGDVHQGATIRAGGNILIMGTLKGNAHAGSQGDRSAAIVAYRMEPEQLGIAGIIARSPEQKTRHPYPEIARLVGTRIVIDPYLSPKSSRN", "output": "Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization."}]}
+{"id": "function_test_3445", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKCDVKTLDGKDAGSIELSDSVFGLPVRTDLLHRMVRWQLARRQAGTHKTKGISEISGTTAKPFKQKGTGHARQGSKRSPQFRGGATIFGPVVRSHAHDLNKKVRKLGLKTALSAKAQAGQLIVLDQAISESGKTKDLLAQLKVLGLEKVLFIDGPEVNEKFALAARNIIGLDVLPQQGANVYDILRRDTLVLTKEAVKHLEERLQ", "output": "One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.; "}]}
+{"id": "function_test_3446", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPRATNKPATRRRRKKILNKAKGYWGRRSKVYKVAKHAVEKGLQYAYRDRRQKKRRFRRLWITRINAATRQHDVSYSQFMGQYRKSDLDMNRKVLADLAVHDPDAFEQIVDHVME", "output": "Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit."}]}
+{"id": "function_test_3447", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAPERWDDEEDSVSPPPVAPRRRFDDEEEDEVLDSWDAAEDSEVEREKAAKAAEAKAKADAEAAAKKKSKSQRIQEHKEERKKKAEEEDSDSEEEDDADKRARLRRAQKDADLKHAEDLFGDIDLNRNRGAPKAIVISDSADPTQAVDLSAMPLFKPTTKEQFARLTSTLIPLLTPHSKKPHYSLWAQEFAKQLVKELNSADVKKIASAMTTMSNEKMREERAADKGSKKSKAAKTKVSLVTSRDNKLDADYDNGDDGLGDDDFM", "output": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation."}]}
+{"id": "function_test_3448", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSPQPHIPVLLAEVIAALAPRNDGVYLDGTFGAGGYSRAILAASACRVWAIDRDPTAVARGKLLEEGSAGRFSMIEGRFGDMDSLLRQQGVNQVDGIALDIGVSSMQIDQPERGFSFAKDGPLDMRMETKGPSAADMVNDTPETELANIIYRYGEERLSRRVAKAIVEARRLKRFERTGELAEVVRKVVPRSGDGIDPATRTFQALRIAVNDELGELERGLEAAERLLAPGGHLAVVTFHSLEDRVVKSFLKARSGEAARPSRHVPQAQGSGPAASFALLSRKAIGPAPDEARANPRARSAKLRAAARTAAPAWETVS", "output": "Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA."}]}
+{"id": "function_test_3449", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRAEIEALAQDIRRSAALLKRHLNWDEALMRLDELNASAENPDLWNDAGAAQKIMRERNELDSAIQGCRALERELADLAELIELGEMEGDQTVIDDAEEQVRALKERAAKMELETLLSGEADHNDCYMEINAGAGGTESQDWAEMLLRMYTRWAEKHGYKVEWLEESAGEQAGIKSATIRILGHNAYGWLKTESGVHRLVRISPYDSAARRHTSFSSAWVYPVIDDTIDIQINESECRIDTYRASGAGGQHINKTDSAVRITHIPTGIAVACQMERSQHQNRARAWDMLRARLYEAELQKREAAAQALEDQKTDIGWGHQIRSYVLQPYQMVKDLRTNVETSDTQGVLDGDLDMFMAASLAARVQGQVDQG", "output": "Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA."}]}
+{"id": "function_test_3450", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPFRSNNPITRDELLSRFFPQFHPVTTFNSGLSGGSFLIEHQGQRFVVRQPHDPDAPQSAFLRQYRALSQLPACIAPKPHLYLRDWMVVDYLPGEVKTYLPDTNELAGLLYYLHQQPRFGWRITLLPLLELYWQQSDPARRTVGWLRMLKRLRKAREPRPLRLSPLHMDVHAGNLVHSVSGLKLIDWEYAGDGDIALELAAVWVENTEQHRQLVNDYATRAKIYPAQLWRQVRRWFPWLLMLKAGWFEYRWRQTGDQQFIRLADDTWRQLLIKQ", "output": "Catalyzes the phosphorylation of thiamine to thiamine phosphate."}]}
+{"id": "function_test_3451", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQNRLQELLTRIGLSLEKPVCDRLLWYLDEMLRWNRRINLTAIENKEEALEKHLLDSLTVVPLLRGDERLLDMGSGAGLPSIPIKIARPQMCVLSVDSVHKKIVFQQHVARQLKLQGFEARACRIQSLSQGESETSFDVVTARALTHLSDLLSMAEPLLNDKGRLIAMKGPDGEAELAECAQQIRKAGFVAEPLQHLSLPLSGSERTLVVLKRKPGR", "output": "Specifically methylates the N7 position of guanine in position 527 of 16S rRNA."}]}
+{"id": "function_test_3452", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MANRIKKGDQVVINTGKDKGKQGEVVRVEGDRVIVSNANVIKRHTKPNPQAGVAGGVVEREASIHISNVNIVNPATGKGERVGFKVLEDGRKLRVFRSSGEALDA", "output": "One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.; "}]}
+{"id": "function_test_3453", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAIYAIGDIQGCYDEFQQLLKEIHFDEQADQLWLAGDLVNRGPKSLEVIRFVHGLGKRAITVLGNHDLHLLAVAAGLQPLHSKDTLAAILSAPDREELITWLRHLPLLYRNSKLGITLIHAGLPPQWDIATAESCARELEAVLQGPNWRDFLAHMYGDKPVQWRDDLKGWERLRTISNCLTRLRYCDAKGRFSLKFKESPGTQTKGGLMPWFKVPHRASHGERIVFGHWATLEVGPYEGPVFALDGGCVWGGQLVALRLDKEEPQWFFVDCQGYSKIT", "output": "Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP."}]}
+{"id": "function_test_3454", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTYLGSIEALLFVAGEDGLSLRQMAELLSLTPSALIQQLEKLAKRYEEDDDSSLLLLETAQTYKLVTKDSYMTLLRDYAKAPINQSLSRASLEVLSIIAYKQPITRIEIDDIRGVNSSGAITRLIAFGLIKEAGKKEVLGRPNLYETTNYFLDYMGINQLDDLIDASSIELVDEEVSLFSMDSINTEDKENNEN", "output": "Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves."}]}
+{"id": "function_test_3455", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIDPDGFRPNVGIILTNDAGQVLWARRINQDAWQFPQGGINPEETPEDALYRELNEEVGLEREDVEILACTRGWLRYRLPQRLVRTHSQPLCIGQKQKWFLLRLISNEQRVRMDLTGKPEFDGWRWVSYWYPLGQVVTFKREVYRRALKELAPRLLARD", "output": "Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage."}]}
+{"id": "function_test_3456", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTGTGKTVTRVDLCEAVYKKVGLSRTESSAFVELVLKEITDCLEKGETVKLSSFGSFMVRKKGQRIGRNPKTGTEVPISPRRVMVFKPSAILKQRINSNGAGGKTD", "output": "This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control."}]}
+{"id": "function_test_3457", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAVQRKYRASRRLGVSLWGRSKDPFNTRNYPPGQHGNMGYKKPSDFGKQFAAHKKFKFYYAISSKQMRNVFLKAYKKRGDTGDNFVGLLESRLSSILYNSGLVPTIFSARQLISHKHVLVNGKTVNISSYIVKVGDVVTLKEKAKNLPAVIAAIQSQEHKVPDYLEVDTQEKSVRYLRVPKYCEVPYPATMEVNLVIEFYSR", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; "}]}
+{"id": "function_test_3458", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTNKTVLHAKHLASGAKMVDFFGWDMPINYGSQIEEHHAVRTDAGMFDVSHMTIVDVQGADAKAFLRRLVINDVAKLATPGKALYTGMLNEEGGVIDDLIIYFFSDTDYRLVVNSATRVKDLAWMTKQSTGFDITITERPEFGMLAVQGPEAKAKVAKLLTAEQIEAVEGMKPFFGVQVGDLFIATTGYTGEDGYEIIVPNNSAEDFWQKLLDEGVVPCGLGARDTLRLEAGMNLYGLDMDETVSPLAANMAWTISWEPTDRDFIGRDVLTAQKAAGDQPKLVGLVLEAKGVLRSHQVVVTEFGNGEITSGTFSPTLGHSVALARVPRSVKVGDTIEVEMRKKLIKVQVTKPSFVRNGKKVF", "output": "The glycine cleavage system catalyzes the degradation of glycine."}]}
+{"id": "function_test_3459", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPRKGSVPKRDVLPDPIHNSKLVTKLINKIMLDGKRGTAQRILYSAFDLVKERSGREAVEVFEEAIDNIMPVLEVKARRVGGSNYQVPVEVRPERRTTLGLRWLVNYSRLRGEKTMEERLANEILDAANNTGGAVKKREDTHKMAEANKAFAHYRW", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."}]}
+{"id": "function_test_3460", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTKKAEELKMHEKDTGSSEVQIALLTGKIETLSAHIKQFKKDKHSSVGLLRAVNRRKKLLEYLKKNKFDSYKNVLTQLNLRK", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.; "}]}
+{"id": "function_test_3461", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSQHPDINSSIDANHLTDDQTSLDANAVIDKEAMPDDSKHIRIVNTFMKRRTHMNKNAELALTAPEFAHYLVNNSFGDGNLDGIDDLRALFADLPNGSDAPLTLEIGFGLGDSFIEMAAAEPSRNFVGVEVHEPGIGKCAYMAGTQNLSNIKIINGDAIQLLKQLPENHIDRIQLYFPDPWQKKRHYKRRFVSAERMAIVTRSLKQGGWFHTATDWEHYAFWMVEVLDGFAGLSNQAGAGNFTDRPDFRPMTKFERRGLERGHGVWDLIYLKD", "output": "Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA."}]}
+{"id": "function_test_3462", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTDLIGFYSDHKIAAPLAIAQRSAKFKPFAAEIARRGILQIATCARLEFYGEKSVLEDIDGKPFFGFSYGRVEGAISIAERLATIAAGVHSQILGEGFISGQLMQAIESGDPNLSIFKVARVAVDLGSAARKRQEFFAEFDYVQIVEDIIADRFSDKAPLDRIYIIGAGMLGQELIRGNVGERFRSTVVITRNPKKLRKRLNTGPKTNVTFMRPSEVGRTREPGSMVVIATTDVDNKYKAILQETLLRLGPRIILDLSSIPVLTREAIGELDYVNMYGDEFLRFIEQNNQRLAPKLPLVVSDIKAALGAAV", "output": "Responsible for the nodulation efficiency and competitive ability of strain GR4 on alfalfa roots."}]}
+{"id": "function_test_3463", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIEVPTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSLEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQESLPYERRNSLNFERLEAQLKACYCRIIFSKAKPSVLALSIIALEIQALKCVELAEGAECLQKHSKINGRDLTFWQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPEMVP", "output": "May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity)."}]}
+{"id": "function_test_3464", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKTLLLTLVVVTIMCLDLGYTTKCYVTPDVTSQTCPDGQNICYTETWCDAWCGSRGKRVNLGCAATCPKVNPGVDIICCSTDNCNPFPKRS", "output": "Binds with high affinity to muscular (alpha-1/CHRNA1) and neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR) and inhibits acetylcholine from binding to the receptor, thereby impairing neuromuscular and neuronal transmission."}]}
+{"id": "function_test_3465", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPKKDVRAFLYDILENMKDIIDFTNDMTFDEFLKDKKTQKAVIRSLEVIGEAVKNLPEDFINKYPQVPWKGMARLRDKLIHHYFGINYEIIWDIVINKVPNDIKEIEEIIKDIEGEDENSI", "output": "Probable toxic component of a putative type VII toxin-antitoxin (TA) system, probably an RNase. Probably neutralized by cognate antitoxin MJ0128. Neutralization may be due to AMPylation by MJ0128."}]}
+{"id": "function_test_3466", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAAATGTRKKKTPRPGQWKLWLLYTAGFVPAVWTFYLGATGQLGADPVKTFEHLLGLWALRFLILTLLVTPIRDLTGITLLRYRRALGLLAFYYALMHFTTYMVLDQGLNLSAIITDIVRRPFITIGMISLALLVPLALTSNNWSIRKLGRRWSSLHKLVYIAIAGSAVHFLMSVKSWPAEPVIYAAIVAALLLWRLARPYLRTRKPALRPRGEAIALRK", "output": "Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain."}]}
+{"id": "function_test_3467", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSASGLPFDDFRELIRNLPGPDLGAERAVREREVTLTKPAGSLGRLEEIVAWLATWTGKRTPQVNRPLVAVFAGNHGVTAKNITPFPPSVTAQMVENFAAGGAAINQICIANDLGLKVFDLALEHPTGDITEEAAMDEHTCAATMAFGMEAIAGGTDLLCIGEMGIGNTTIAAAIALALFGGTAEDWVGPGTGSTGELMQRKLAAVRQAVALHQPHLQDPLEVLRCLGGREIAAMAGAILAARMEKIPVIVDGFVASAAAAVLYAANPEAIDHCMFGHVSAEPGHRKLLAKMGKEPLLDLGMRLGEGTGAALAANIVKAAALCHSGMATFEQAGVSASK", "output": "Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB)."}]}
+{"id": "function_test_3468", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSTSTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLTEVQSEFGLTTVQAASLISAAFISRWFGGLLLGAMGDRYGRRLAMVSSIILFSVGTLACGFAPGYTTMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVAAQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHAGKAPVRTMVDILYRGEHRIINILMTFVAAAALWFCFAGNLQNAAIVAGLGLLCAVIFISFMVQSSGKRWPTGVMLMLVVLFAFLYSWPIQALLPTYLKTELAYDPHTVANVLFFSGFGAAVGCCVGGFLGDWLGTRKAYVCSLLASQILIIPVFAIGGTNVWVLGLLLFFQQMLGQGIAGILPKLIGGYFDTAQRAAGLGFTYNVGALGGALAPILGALIAQRLDLGTALASLSFSLTFVVILLIGLDMPSRVQRWLRPEALRTHDAIDDKPFSGAVPLGSGKGAFVKTKS", "output": "Catalyzes the proton-dependent transport of sialic acid."}]}
+{"id": "function_test_3469", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVEKQFNIDLELNDTGHIDPFLQDEDKLKLEELIPRILFERKSFLNVTEDSLRKEIDNSLKISEEDALDTEESREDTVEADQQEVFNKHKFELSKNINNALNETQLSLDFVSLLISSVKPSLAKSTISPHLSKFVKPTSLNSDRLGQDSNDNQESKATDSFGQGWKLESLGKITDLFREASTNLNDQVIKERRYWNMINLVLANDEVLFRMRDPQNNARAIGVKYGYGDSGSNFHDQGLALLRKDNQTGEISFHPISSINNAKIVEKVSRFIRVKILSQIDGDYMLTGQSIFNFDFEKSKQSIINDIEKARFFLFEEDLFHQLIREAKLLVNYNVSIISNKIIIEINNIIIEIESIVYDELNEEELENYYQNVNEYSTLHNKKCQLILNYLKLMLCCYYKYNLKLKQKVPTALTKWKQSNSHPLILRPLVGNMRHELNLLNMKSVLDRLMHAHESELSYSKLDVEKFINLATRSKKQNPFQKSIEKPISKFHLVLCNKTSNMLDVNIQLTTNESFVNLIINMTIIRFETEDDFKNNVNGINVLQLGFSDFNEIEECLDWSIQNFV", "output": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity)."}]}
+{"id": "function_test_3470", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAPRQSKTAKRNKTQNKTRTVDSEVFSDSAAKNLLADQPKLTPKSKVKKISKLALKKQQAKIRLYGAKNGKEYREDQLNIPTLNKAIVPGVKAKRGKKGKKFVDDNDTLTMNRLVKSINDKYDQVNESKLEKSRRLEEIRDLKRQEIERKEQQKKDKLEGKKDELRSKASVARSTRRKNAKARRADEESQEQEEESPKKKKKVSFV", "output": "Required for efficient assembly and nuclear export of the 60S ribosomal subunit."}]}
+{"id": "function_test_3471", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGKIIGIDLGTTNSCVAVLDGDTPRILENAEGERTTASVIAYTDGETLVGQPAKRQAITNPQNTLFAIKRLIGRRFEDEEVQRDIEIMPYKIIKADNGDAWVEAKGQKMAAPQVSAEILKKMKKTAEDFLGEEVTGAVVTVPAYFNDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGLDKKGGDRTIAVYDLGGGTFDISIIEIDNVDGEQTFEVLATNGDTHLGGEDFDNRLINFLVDEFKKEQGFDLKNDPLAMQRVKEAAEKAKIELSSAQQTDVNLPYVTADATGPKHMNIKVTRAKLESLVEDLVVRTLEPLKVALADADLTIDGITDVILVGGQTRMPMVQAKVAEFFGKEARRDVNPDEAVAMGAAVQGGVLAGDVKDVLLLDVTPLSFGIETMGGVMTKLIEKNTTIPTKADQTFSTAEDNQSAVTIHVLQGERKQASYNKSLGQFNLEGIQAAPRGMPQIEVTFDLDADGILNVSAKDKSTGKEQKITIQASGGLTDEEIEAMVQEAEANKDADKKFEELVTARNQADQMIHGTKKQIEEAGDDLPTDEKEKIEAAITALEGVKSGDDKEAIDAKTQELMQAAQKLMEIAQQKAQAQQGAQAGEQPKQEDDVVDAEFEEVK", "output": "Acts as a chaperone."}]}
+{"id": "function_test_3472", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLSVILKESVRNLGKAGVVTKVKPGYARYLLAQKKAVRATKENLKILEEQHISIQQENLEKLEAAKALQVSLKDEFLIIIRQAADDGKLFGSVTPKCISKLLSDKGYNIHYHNIFFHSVIKYIGEYVVNLELHHDLVVPMMLYVVKNDLGAMQAQKLHLDKQKKEEKAKDEVSATEKDEELMLSSVTNDNDGDGAKEIVVEGTEESQ", "output": "Binds to the 23S rRNA."}]}
+{"id": "function_test_3473", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSSRSRHDVKGPAGVSAHGPSTRQLRVAEEVRRVLAELFARTEFRDPELLDVRITVTEVRISPDFRHATAFVTRLGRSDVEVLLPALKRVAPFLRTGLSKALNLRTVPEIHFQPDTALDNAMELDEIMRSPEVQRDLNSKPE", "output": "One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA."}]}
+{"id": "function_test_3474", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIEINVYYKKWYSTIKKPKIFVKNVIKSSLINLNIYEYKPIISIVLANNILLQKLNYEYRNKNKPTNVLSFPYDKLNKKCNLGEIFLSLDTLIQESIDLNIPIEHHTCHMLIHGLLHILDYNHEEPLMQYIMESIEIKLLDKLGIRNPYVSRETIYP", "output": "Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA."}]}
+{"id": "function_test_3475", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSLSDPIANFLTSIRNGQLSMNKVVTVSYSYVIHAILQILLSEGYIDGFTEKLRSTNIKFFEVKLKYYNGVPVINRICRVSKPGKRCYCSAKGMPKFYNGLGLYIISTSKGIMSDYNARKSGVGGEILCGVF", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit."}]}
+{"id": "function_test_3476", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYDGIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTYVGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDDIDQGVKGSDVIYTDVWVSMGEPDEVWKERLELLKPYQVNKEIMDKTGNPNVIFEHCLPSFHNADTKIGQQIFEKYGIREMEVTDEVFESKASVVFQEAENRMHTIKAVMVATLGEF", "output": "Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline."}]}
+{"id": "function_test_3477", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRTYEVMYIVRPNIEEDAKKALVERFNGILATEGAEVLEAKDWGKRRLAYEINDFKDGFYNIVRVKSDNNKATDEFQRLAKISDDIIRYMVIREDEDK", "output": "Binds together with S18 to 16S ribosomal RNA."}]}
+{"id": "function_test_3478", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDLKQYVSEVKDWPSAGVSFKDITTIMDNGEAYGYATDQIVEYAKEKNIDIVVGPEARGFIIGCPVAYSMGIGFAPVRKEGKLPREVIRYEYNLEYGTNVLTMHKDAIKPGQRVLITDDLLATGGTIEAAIKLVEQLGGIVVGIAFIIELKYLNGIDKIKDYDVMSLISYDE", "output": "Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis."}]}
+{"id": "function_test_3479", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLEGIVRESIGRKAAKALKRDGYLIANIYGKGLENINAAFKVNEFIKEVRKKTTLIFDVKVGSQTLSVVVVDYQKDPVTAELKHVDLKVAQKGVISKYMVPVKITGTAIGLKNKGVLIQSKRRLKVKCAAENLPNFFELDVSKLDVGDALLVRDIVVPAGVTMIDADRVAVVGVEKAR", "output": "This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance."}]}
+{"id": "function_test_3480", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEEFQGHRELYRSWQHNFFYPLIFQEYIYTFAYDRGLNKLILLENVVDQRYSLLTVKRLITRLYHQNHLILSVNDSNQNEIFGHKPKKNLYSQMITEGFAVIVEIPFSLLLISSLDGKEKKIGKSTNLQSIHSIFPFLEDKFLYLNYVLDILIPYPTHLEILVQTLRYWLKDASSLHLLRFFLYECRNWTSRITSKESISFLKKRNRRLFLFLYNFYVCEYEYFFVSLRNQSSYLRSTSFGALLERIHFYGKFKYLVKVKDFAVILWFFKEPFPHYVRYQGKALLASKGTSLLMHKWKYYFIYFWQCYFSVWSQPRRIYINQLSNYSLDFMGFLSNVRFNSSVIRSQMLENSFLLENIRKKFDTIVPISPLVGSLAKAKFCNVLGHPIGKSVWTDLSDSDIIDRFGRICRNLSHYYSGSSRKKNLYRIKYILRLSCARTLSRKHKSTVRAFLKRLGSEFLEEFFTEEEKVLSLILPRDSSTSGGLYRGRVWYLDIICIHNLVNDQ", "output": "Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns."}]}
+{"id": "function_test_3481", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSSSTRVGLKEQLHPLIRDLATGIEATWQRWLNLEPYAAMPADLGYIEGKLEGERLQIENRCYQSREFRKLHLELARVGNNLDILHCVLFPRTTFDLPMFGADLVGGRGQISAAIVDLSPTTIARELSNDYIAGLTALPNPTFQGLRELPTWGDIFSSFCLFIRPGSPEEEAAFLDRALGFLQVHCQQAAAATALTDPEAIATVLEQQRYYCEQQRRNDKTRRVLEKAFGDDWADRYMTTMLFDLPSD", "output": "Catalyzes the four-electron reduction of biliverdin IX-alpha (2-electron reduction at both the A and D rings); the reaction proceeds via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin."}]}
+{"id": "function_test_3482", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MARVKRGVTARARHKKVVALAKGYRGRSKNCYRAALQRLEKALVYAYRDRRNRKRDFRRLWIVRINAAARQWGIKYSQLMKGMALCGIELNRKMLAEMAVNDKAAFEKVVSAVAGTCGYACAVNQQDK", "output": "Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit."}]}
+{"id": "function_test_3483", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLVALAAIGVTVLLFLIKALGSGAKKAPVTLLDPNAKYPLPLIEKQEISHDTKKFRFGLPSAEHVLGLPVGQHIYLSAKVNGSLVVRAYTPVSSDEVKGHVDLVVKVYYKNVNPKFPDGGKMSQHLDSLKIGETIDFRGPNGLLVYKGKGKFAIRPDKKAEPKIKVAKHVGMLAGGTGITPMLQLIRQITQDPNDNTKCYLIFANQTEDDILLRYELETVAKSHPEQFKLWYTLDRPPQGWKYGSGFVTADMIKEHLPPPSEDVLVLMCGPPPMIQFACQDNLTKLGYPEAGRFAY", "output": "NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis and drug metabolism."}]}
+{"id": "function_test_3484", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTALNWKPFIYGGLASITAECGTFPIDLTKTRLQVQGQANDAKYKEIRYRGMLHAIVRIWKEEGVKALYSGIAPAMLRQASYGTIKIGTYQSLKRLFVDCPEDETLVINVFCGVLSGVVSSCIANPTDVLKIRMQAQGSLIQGGMIGNFINIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVYTHFLASFTCGLAGALASNPVDVVRTRMMNQRSIRNVSNSSYKGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKKLNL", "output": "Probable transporter."}]}
+{"id": "function_test_3485", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTANGLLQICGYLGVLLALAKPLGSYMAAVYEGRSATVRVLASVERFIYRITGIDPEAEMRWTGYASAFLVFNLLGVLAVYALQRCQGFLPLNPQGLPAVAPDSAFNTAISFATNTNWQGYGGEMTLSHLTQMLGLTVQNFVSAASGMAVLVALIRGFVRRNADTLGNFWVDLTRSILHILLPLSFLLALLLIGQGVVQTFEPYRNVTLVEATGYDRPKQDEGGHPLVDADGNPVTEHVTVSEQTLALGPAASQVAIKQLGTNGGGFFSVNSAHPFENPTPFSNFLEMLAILVISGALCHTFGVMVGDTRQGWVILAAMTLIFVPLLFVTVLCEQGGNPAFAALGVDPAGGNMEGKETRFGIVNSALWATATTAASNGSVNAMHDSFTPLGGLVPMWLMQLGEVVFGGVGSGLYGMLVFAIVAVFVAGLMIGRTPEYLGKKIEAYEMKMAAIVILVPPLMVLGGTAVAVMLDAGKSSVFNPGAHGFSEILYAFSSAGNNNGSAFAGLAANTPFYNLMLGLAMWFSRYWLAVPVLAIAGALAAKNYVPPGAGTLPTHTPMFVGLLVGVVIIVGALTFIPALALGPIVEHLMMIGAR", "output": "Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel."}]}
+{"id": "function_test_3486", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNKTPMTTRGAEKLREELNHLKTVARPRVIEAIAEARAHGDLKENAEYQAAREQQGFIEGRIKEIEAKLANAQIIDVTRLNPGGKVVFGATAEIEDLASGEVVTYQIVGEDEAEIKEGRISVTSPIARALIGKQEGDVATVQAPGGTREYEIVSVRYV", "output": "Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides."}]}
+{"id": "function_test_3487", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDGVIKSIFTFILILEFIIGNLGNSFIVLVNCIDWVKRRKISLVDQLLIALAISRISLVWSIFGSWCVSVVFPALFATEKLLRMLTNIWTVTNHFSVWLATILGTFYFLKIANFSNSIFLYLKWRVKKVVLVLLLVTLVLLFLNILLINIHINASINGYRGNMTCSSASCNFIRFSSAIALTSTVFILIPFTLSLATFLLLSFSLWKHRKKMQHTVKGYRDVSTKAHRGVMQTVITFLLLYAVFFLTFFVSIWISERLKENQIIILSEMMGLAYPSGHSCVLILGNKKLRQASLSVLWWLRYRFKDGELSGHKEFRESS", "output": "Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity)."}]}
+{"id": "function_test_3488", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MITFLPITFSILIVVIFFIGNFANGFIALINSIEWVKRQKISFAGQILTALAVSRVGLLWVLSLHWYATEFNLAFHSVEVRSTAYNVWVVTNHFSNWLSTSLSMFYLLRIATFSNLIFLHLNRRVKSVILVTLLGPLLFLVCQLFVMNMNQIVRTKEYEGNMTWKIKLKSAMYLSNTTVAMLANFVPLTLTLISFLLLICSLCKHLKKMRVHGKGSQDPSTKVHTKALQIVTSFLLVCAIYFLSIILSVWNSGGLENKPFFMFCQAIKFSYPSTHPFILIWGNKTLKQTFLSVLRNVRYWVKGQKPSSP", "output": "Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency (By similarity)."}]}
+{"id": "function_test_3489", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIQKLLARDFFNNKEQPIILEPRAPQEIFPEHTHDFDELVIVKHGSGRHILNGYPHDLYPGVVLYIQAQDHHSYENLQDLCLTNILIQSNNNFKYLNNIDILLNGLKPENSSYQLINKKTAEYIDSLLEKINAIDESYNLQNECLFFQVLSSIQAHQFNDSGYGNTEEKGRQMIRWLENNFEKEIDWEELAEKFALPIRTLHRYIKSQTGHTPQNYVTKLRLAQAYYQLKYTEKNIINIAYDCGFNDSSYFSTCFKNEYSIAPRELRI", "output": "Activates expression of the rhaBAD and rhaT operons."}]}
+{"id": "function_test_3490", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEFLKKLEVWFVVGSQDLYGDEALKQVNANAEQITRYLNDQNPFIQIKLKPLATTPEDILSLCQAANYEENCVGVIAWMHTFSPAKMWIGGLTRLNKPLLQFHTQLNKNIPWNEIDMDYMNLHQTAHGDREFGFMVSRFRKPRTIVVGHWQSESVKQKLDRWMRVLAAIYDQQHLKVARFGDNMREVAVTEGDKVEAQIKFGYSVNGYGLYQLVNSINTVNDEDITALVKEYEASYQLADSLKDGGEKRQSLIDSARIELGLKAFLDKGGFKAFTDTFQNLAGIKQLPGLPVQRLMAQGYGFGAEGDWKTAALVRAIKVMSYGLPNGCSFMEDYTYNLDDNNEIVLGAHMLEVCPSIANNKPILDIKPLGIGGKEDPARLIFTSKSGKATASTIVDLGNRFRMITADMQAVDKPQDMPNLPVGHAFWKLEPNFDIGTQAWILSGGAHHNVFSLDIDADMLRTFAEYFDIEFIHINVKTELPNLKNELRWNEAAYK", "output": "Catalyzes the conversion of L-arabinose to L-ribulose."}]}
+{"id": "function_test_3491", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRLNTLSPAEGAKHAPKRVGRGIGSGLGKTAGRGHKGQNSRSGGGVRRGFEGGQMPLYRRLPKFGFTSRKAMITAEVRLSELALVEGDVIDLNTLKAANVVGIQMEFVKVILSGEVNRAVTLRGLRVTKGARAAIEAAGGKIEE", "output": "Binds to the 23S rRNA."}]}
+{"id": "function_test_3492", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLCGRFAPTPSGALHLGNARTALLAWLHARRAGGRFILRIEDIDRARSRPHLAEQAIADLRWLGLDWDEGPDVGGPHGPYCQSEREELYRDALARLQAEGRLYPCYCSRAQLMAIASAPHGLTSEGPAYPGTCRRLTPEERRAREADGKTPSLRFALPDEEIAFTDLIAGPQRFPPGAGGDFVVLRADGVIGYQLAVVVDDALMGVTHVLRGGDLLDSTPRQILLYRALGRPVPAFGHLPLLLGPDGARLAKRHGAVTLAGIRAAGTSPETVVGHLAYLSGLVDQPEPVRPEELIPVFDLARIPREPVRIPAETIAALSGGTA", "output": "Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon."}]}
+{"id": "function_test_3493", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLSRILGVRNHSFRAFSTIGVCYNKSNTSPKKYLSPNEFASQKQVDEIEEQAYKQNLLNEEYKYDPKYLSENELNPISKRPIPLNVELLKYKPVQLPPTHGHEVAKIEFKGYDKDDLIRASEFAARAAFYLGIPCSKVQSLKTEKRLYTVIKSPFAQAKSKENFKRTTYGRKVYAYDATPEVVDLWLSFINKHAIEGVKYNALIHTRESLDFCEKLDALSADDMHMPDAYKGSDDPIANKVEELLKSDTFKKYFDEANIAESPKESK", "output": "Involved in mitochondrial genome encoded proteins translation. Involved in the binding of tRNA to the ribosomes (By similarity)."}]}
+{"id": "function_test_3494", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSTNLPNSCLVQIALTVSTHSGPQLIYHYPPSNYATATNSKKTHHPDIKKRYEYTDSENNSSSDDYSSGLSDSELSTDYADCSSDASESSLDSLPQSNHEDTVNSSTNNTFINNGLRSRQSQISANKLFQVLNQNNNNVAINGENSLRESLHSIRTSTNMSSTTDPRPEDELDAVDEELKILVDDLLDGSIFQQDTFQDISKVLNFNTEFVAELCSPRKEMCNTRFEFTVDDLCFLGLPIHADHKGRWKKSKKRKQASKRSARSSTARNSISRNSVGRNSIGRNRSKTESQGHINDVEEPADDENSDYEPSKSEMLNEMYCVPDAENDEFESLQQSINMFQVCFIMNPKIIEYNERVDDMYHYVVTRLSLILRYIQGKTGYVTRECVKIMKCKDEVSKHSRYYESLKSPWSKGKYMYERILYESSLARALTKCFNCIHNNEIANLEIDGDKIVSLQIPIKNEFSILPNLKEDAVLRGSFLSSILNESFIGRSTSLTNEDSDNLYANHDRLLDYGLLLLDEPENIIKGLENASFDNGVTDLLLINLVRQLKPTIRLGQYKLLIKELIDSNDSSYDDQFCETTLKSLCLHLIYWRHARLILPISSRNTYIVSPLAPISGFSTDDFKHGEYDTLIRQQEVPVNNNDEPSLIYQNKKVFNEKFPSLPSLPSFLQLMSTQKPRPFGHIIPSNEHKSMYLNALAWLMRYGYLTQLLTFVYVRVDKRIKIAVDEDLEKDNLRSNKHEKSGNFVTGGENYNSSEFDDLEMINDNDFTIILEPERNTALEKRWLYKCAEALPTDLQTLFRQVVKYFNGKVSLEYIMIKEGIPKNEIKRLLQALGKYIVEVKHW", "output": "Mediates inactivation of the TORC1 complex in response to amino acid starvation. Required for meiotic nuclear division (By similarity)."}]}
+{"id": "function_test_3495", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLEQMGKAAKAASYQLAVLNTAQKDRALLTIADLLEVESATILAANVLDLADARQNGMSEALLDRLLLTQERLSAIASDVRQVCRLTDPVGQVIDGSMLDNGLKLERRRVPLGVVGVIYEARPNVTIDVASLCLKTGNAVILRGGKETYRTNAATVKVIQQALSQCDLPAAAVQAIESPDRELVNQLLKLDRYIDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHIYADDSIDFDKALTVIESAKVQRPSACNSLETLLVNRSIADRFLPELSKKMAASGVTLHASSLAMPYLTSGPANVVAVEDANYNDEWLSNDLNVTLVDDLDAAVAHIREHGTQHSDAILTRSLSNAERFVREVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTTYKWIGYGDDLIRA", "output": "Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate."}]}
+{"id": "function_test_3496", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSREEQPYIVATDGIVDALTKISSVFSAYLSANIHILNKYINYLRRVTSLKNERSIMIKIVKKLRFFNDTLLSTDLAQLQTTYEGEEPELALNIQTFASYLVKCLETIDLLNYFLLKPLQKELIAKTLNFDLVFPEDITDTVEDTYNHFVKFTQWSIESLSIDDPLLDIEVVQFSLRCAEEDQSYAEETDNIFLQEVLPVKDSQEYETLTLQWLDVLNGKLAILGERFEKVADDWYKKFGKNRS", "output": "RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell (By similarity)."}]}
+{"id": "function_test_3497", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQDSSLNNYANHKNFILMLIILFLMEFARGMYILSYINFLPTVTSIAVAITSLAFSIHFIADASTNFVIGFLLKKFGTKIVLTTGFILAFTSLFLVIWFPASPFVIIFSAMMLGIAVSPIWVIMLSSVEEDKRGKQMGYVYFSWLLGLLVGMVFMNLLIKVHPTRFAFMMSLVVLIAWILYYFVDVKLTNYNTRPVKAQLRQIVDVTKRHLLLFPGILLQGAAIAALVPILPTYATKVINVSTIEYTVAIIIGGIGCAVSMLFLSKLIDNRSRNFMYGVILSGFILYMILIFTLSMIVNIHIVWIIALAIGLMYGILLPAWNTFMARFIKSDEQEETWGVFNSIQGFGSMIGPLFGGLITQFTNNLNNTFYFSALIFLVLAVFYGSYFIANREKAK", "output": "Proton-coupled antiporter flippase that catalyzes the translocation, from the inner to the outer leaflet of the cell membrane, of the lipid-linked disaccharide (anchor-LLD) that anchors lipoteichoic acids (LTA) to the cell membrane."}]}
+{"id": "function_test_3498", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDSNTVSSFQDILLRMSKMQLGSSSEDLNGMITQFESLKLYRDSLGEAVMRMGDLHSLQNRNGKWREQLGQKFEEIRWLIEEVRHRLKTTENSFEQITFMQALQLLFEVEQEIRTFSFQLI", "output": "Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs). Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell. Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain. This domain is believed to allow recognition of RNPs bound to the protein M1. Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized. Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane. May down-regulate viral RNA synthesis when overproduced."}]}
+{"id": "function_test_3499", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAKEKGLTPQSQDFSEWYLEVIQKAELADYGPVRGTIVVRPYGYAIWENIQQVLDRMFKETGHQNAYFPLFIPMSFLRKEAEHVEGFSPELAVVTHAGGEELEEPLAVRPTSETVIGYMWSKWIRSWRDLPQLLNQWGNVVRWEMRTRPFLRTSEFLWQEGHTAHATREEAEEEVRRMLSIYARLAREYAAIPVIEGLKTEKEKFAGAVYTTTIEALMKDGKALQAGTSHYLGENFARAFDIKFQDRDLQVKYVHTTSWGLSWRFIGAIIMTHGDDRGLVLPPRLAPIQVVIVPIYKDESRERVLEAAQGLRQALQAKGLRVHLDDRDQHTPGYKFHEWELKGVPFRVELGPKDLEQGQAVLASRLGGKETLPLAALPEALPGKLVAFHEELYRRALAFREAHTRKVDTYEAFKEAVQEGFALAFHCGDKACERLIQEETTATTRCVPFEAEPEEGFCVRCGRPSAYGKRVVFAKAY", "output": "Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro)."}]}
+{"id": "function_test_3500", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAVIADPETAQGFRLAGLEGYGASSAEEAQSLLETLVERGGYALVAVDEALLSDPERAVERLMRGRDLPVLLPIAGLKEAFQGHDVEGYMRELVRKTIGFDIKL", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane."}]}
+{"id": "function_test_3501", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKKDIHPKYEETTVTCACGNVINTRSTVKDIKVEICSQCHPFFTGKQKLVDTAGRIDRFKKRYNIKD", "output": "Binds the 23S rRNA."}]}
+{"id": "function_test_3502", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKLILTADVDHLGAVGDTVEVKDGYGRNFLLPRGLAIVASRGAQKQADDIRRARETKAVRDLDHANEFKTAIEALGPVTLPVKTAGDSGKLFGSVTAGDVVAAIKKAGGPNLDKRIVRLPKAHIKALGTHPVAVHLHPEVDVEVPLEVVPQS", "output": "Binds to the 23S rRNA."}]}
+{"id": "function_test_3503", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "METGHPPSLQELCVVVLMRHHAQLEDIGHMPYALVRRVLLKMSAEQLLRLERASPALLLEDEEAWQQLLKKDFPTNVHEVWVARKKDVYEYYLESVRELGPQVLEDRALVRSLLRAAVCKDPVLFKYRVPSRQLYQRYVHEDARRQELSAARLRQSTLQLQQEKQKTRITQLEDPLYLERELNAGRQRAAPQRSSIYLKSFKELRQRQAHFRSGGYDPTQRRIVRVQTPSAQPAASLHPPPQSAPMAGSPQKPAPPEQPLAASPTPEAPGPLAQRRRPSARRQPPPASPAKRRSALFSSPALSTLLPQQDDTDSDTGGRPPKKPRVYIHTPR", "output": "As part of the CRL3 E3 ubiquitin ligase complex; polyubiquitylates monoubiquitylated RNA polymerase II subunit RPO21 to trigger its proteolysis; plays a role in global genomic repair."}]}
+{"id": "function_test_3504", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEALVYTFLLVSTLGIIFFAIFFREPPRISTKKMK", "output": "Seems to play a role in the dimerization of PSII."}]}
+{"id": "function_test_3505", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEWNYLYNHFDPVAFDLWGLKVHWYGIAYVLALLVALWVAKWIAKKDAYPLSNEQLESYFIWVEVGVILGARLGYILFYDPFTAYYLTHPWQIFNPFQNGEFIGIRGMSYHGAVIGFLIASFLFAQRHGVKFWMLMDLVGISVPLGYVFGRIGNFLNQELIGRVTEVPWGIYVAGVLRHPSQLYEAFLEGIVLFVILYAWRSRVKFTGQLGIMYLILYALARFVAEFWREPDAQIGYLVGGVTMGQLLSLAMAIPCLVLWGYLAKKERGKIL", "output": "Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins."}]}
+{"id": "function_test_3506", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDDSIDEEVISGGSTITVEFSGGAETLFGGVKEHIVPLDGSKIVLLEEMLRWLRDHLLTGDAGLFLQENTVRPGILVMINDTDWDLMGETEYILQPGDHILFISTLHGG", "output": "Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates."}]}
+{"id": "function_test_3507", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIASKFKIGQQVRHKLLGYLGVVIDIDPEYSLEKPTLDEVTKNDSLRKFPWYHVVMEDDEGKPIHTYLAEIQLGYEDTVIHPEQSTLDDLAESIRLQLQTPRLRN", "output": "Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress."}]}
+{"id": "function_test_3508", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNWRSERIWIELITGSRKTSNFCWACILFLGSLGFLLVGTSSYLGRNLISLFPSQQIIFFPQGIVMSFYGIAGLFISSYLWCTISWNVGSGYDRFDRKEGIVCIFRWGFPGINRRIFLRFLMRDIQSIRMEVKGGLYSRRVLYMEIRGQGAIPLTRTDENFTPREIEQKAAELAYFLRVPIELK", "output": "Seems to be required for the assembly of the photosystem I complex."}]}
+{"id": "function_test_3509", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLKIGSHVSMSGKKMLLAASEEAVSYGATTFMIYTGAPQNTRRKPIEELNIEAGRKHMEQNGIEEIIVHAPYIINVGNTTKPETFQLGVDFLRMEIERTSALGVAKQIVLHPGAHVGAGADAGIQQIIKGLNEVLTPDQTVNIALETMAGKGTECGRSFEEIAKIIDGVKYNEKLSVCFDTCHTHDAGYDIVNNFDGVLNEFDKIVGIDRLQVLHINDSKNVRGAGKDRHENIGFGHIGYKALHHIVHHPQLTHVPKILETPYVGEDKKDKKPPYKLEIEMLKNGTFDEGLLEKIKAQ", "output": "Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate."}]}
+{"id": "function_test_3510", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTKGILGRKIGMTQVFAENGELIPVTVIAANPNVVLQKKTTETDGYNAIQLGFEDKREKLTNKPEQGHTAKASTTPKRFIREIRDADVDGLEVGQEVKVDVFATGEIVDVTGISKGKGFQGVIKRHGQSRGPMSHGSRYHRRPGSMGPVAPNRVFKGKKLAGRMGGDQVTIQNLEIVQVDTERNLLLVKGNVPGAKKSLVVVQGAVKVSK", "output": "One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit."}]}
+{"id": "function_test_3511", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFNDIGPLELVTLVVLAVLVFGPDKLPKMIQDVTRTIRKIREFSESAKQDIREELGPEFKDFEFEDLNPKTFIRKQLDNDELGLKEIRNGFDLKKEMAEVTDAVHGRESETSASSSSANGSAGGTVDMTKKREQLEADERPPFDADAT", "output": "Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation."}]}
+{"id": "function_test_3512", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNKTLNPQEVWIKAVRNLEGFFSSPRVIGYLKKASPSIEGESLIITFPNSHLASVMDDIEVYDATKKTILDSYPSIKEIKITISPDVLEKEITEEINDLVQSMEEEDFALIDHTKPVIPNFFDQNTRVNFGGGPNNHHPTTGVNPRFTFDNFVVGKSNELARAASISAAERPGKSFNPLFIYGDSGVGKTHLLHSIGNYAKFLFPSLRIKYVSSEDFTNDFINSISSGTSQKFQEKYRQIDILMVDDIQFLQKKQETQESFFHTFNSLHNSSRQLVISSDLPPKQLMGFEDRMRSRFECGLVCDIQKPDLETRIAILQKKCQNEKKEVSMEILTYIASCFSSSVRELEGALLRIFALASFNKEEINMTLAQKVLEDLGAQRGDKIDPIEIIEITAKHYDLAASDLCGNSRVANISIARQIAMYLCRELTDVSLPKLGYIFGRDHSTIIYATRRISDLIGKDRKTFSDIYKLTQFILRR", "output": "Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids."}]}
+{"id": "function_test_3513", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSTGLFDFNGTLPVMGLQVVLLSWLLEQILYSPIQGVIQKRQNKIQQELQLAADQLQKAQQLTQEYQTQLQKAREKARERIRQVQQEAQTMMEDQLKQAQQQMTQLFNEAMQQLEQQKQQALMNLSNQVDEVAKFILSKLMKQ", "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "}]}
+{"id": "function_test_3514", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPRKGYIGKRDVLPDPMYNSKVLTKLINSLMYDGKKGLAQKICYDAFDVIQNKTGKEPMEVFEEAMNNVMPLLEVKARRIGGATYQVPLEVRPERRQTLGIRWILIAARKRGEKYMSERLAGELMDAANNLGAAVKKREETHKMAEANKAFAHYRY", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."}]}
+{"id": "function_test_3515", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDSFGRAPPLWPQSALPRVPGAAPSSSGLPWSRVGEIAIFTFVAVLALYLLWSWVGRDLLLVLKARRGGTTEELTFGPRERHSLPAVAVARVENPPCPSGSVEARPFTG", "output": "Involved in the viral transport within, and between cells."}]}
+{"id": "function_test_3516", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MACCRCDSSPGDYSGALLILFISFVFFYITSLSPQGNTYVHHFDSSSVKTQYVGISTNGDG", "output": "Cell-to-cell movement function."}]}
+{"id": "function_test_3517", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MELKVTTLEGKEAGSVQLSDAIFGLEPRQDIIARCVQWQLNKRQAGTHKAKGRAEIWRTGKKMYKQKGTGGARHGSARVPQFRGGGRAFGPVVRSHATDLPKKVRALALKHALSAKAKDGDLLVIDKAALEAAKTKALLGHFSGLGLTNALIIDGAELNNGFAAAARNIPNMDVLPIQGINVYDILRRQKLVLTKAAIDALEARFK", "output": "One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.; "}]}
+{"id": "function_test_3518", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEGCTKDGAAVQSSGASTAGSIFWWLKDRSLGRGICVDPARDNFRTMTSLYSSIHPADSVNLSTRTHGAVFNLEYSPDGSVLTLACEQTEVLLFDPLSSKHIKTLSEAHEDCVNNIRFLDNRMFATCSDDTTIALWDLRKLNSKACTLHGHTSWVKNIEYDKNTRLLVTSGFDGNVIIWDTNRCTEDGCPHKKFFHTRFLMRMRLTPDCSKMLISTSSGYLLILHELDLTKSLEVGSYPILRARRTASTSDMTSTSSETRPSSSPCHNSDSGPLFEKHMSRSSQREGTSPRNSLEVLTPEVPGERDRGNCITSLQLHPKGWATLLRCSSNTDDQEWTCVYEFQEGTPVRQVSPRCSLRLTHYIEEANVGRGYIKELCFSPDGRMIASPHGYGIRLLGFDSQCKELVDCLPKEAGTLQEIRSLYSHKDVVLTTKFSPTHCQIASGCLSGRVSLYQPKF", "output": "May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex."}]}
+{"id": "function_test_3519", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGQKVNPNGIRLGIIKSWSSTWYANTKEFSKNLISDFKVREFLKKSLSKAYVSKLIIERPAKSIRINIYTARPGIVIGRKGEDVDKLRKEISNITGVPAQISITEIKRPELDAKLVSENIASQLERRIMFRRAMKRAVQNAIRLGAKGIKVEVSGRLGGAEIARKEWYREGRVPLHTFRADIDYNTSEAHTTYGIIGVKVTIFKGEILGNSSPYINEKKYMPTKKGNKKIRKYTKE", "output": "Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation."}]}
+{"id": "function_test_3520", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNETVANNKETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFQALSNPALYENDAELGVKLSFNEEHNTLTISDNGIGMSREEVISHLGTIAKSGTAEFFSKLSQEQSKDSQLIGQFGVGFYSAFIVADAVTVRTRAAGLSADQAVLWHSAGEGEYTVEDITKESRGTDIILHMREDGKEFLNEWRLRDVIGKYSDHIGIPVSIQTRVRDEEGKETEEVKWEQINKAQALWTRNKSDISDEEYQEFYKHVSHDFADPLLWSHNRVEGKNDYTSLLYIPSKAPWDMMNRDHKSGLKLYVQRVFIMDDAEQFMPSYLRFVRGLIDSNDLPLNVSREILQDNKVTQSLRGACTKRVLTMLERLAKNDTDKYQTFWKEFGLVMKEGPAEDYANREKVASLLRFASTEVDSAEQTVSLESYVERMKEGQDKIYYLTADSYAAAKNSPHLEQFKAKGLEVILMFDRIDEWLMNYLTEFDGKQFQSITKAGLDLSQFEDEQEKEKQKETEQEFQSVVERTKSYLGDRVKEVRTTFKLANTPAVVVTDDFEMGTQMAKLLAAAGQAVPEVKYIFEINPNHTLVKQMADETDEEAFGRWVEVLLGQAMLAERGSMEDPSQFLTAINSLLTKG", "output": "Molecular chaperone. Has ATPase activity."}]}
+{"id": "function_test_3521", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRCPKCNYLKSSVVDSRQAEEGNTIRRRRECENCHTRFTTFERIEELPLLVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSSAIEKVVNDIEQKIRSDYDSEVSSVVIGNLVMDELAELDEITYVRFASVYRSFKDVDEIEALLQQITNRVRSKKKRKADETN", "output": "Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes."}]}
+{"id": "function_test_3522", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAHVCSVILVRRSFDIHHEQQKISLHNESILLLDKNLADDFAFCSLDTRRLDIEELTVCHYLQNIRQLPRNLGLHSKDRLLINQSPPIQLVTAIFDSFNDPRVNSPILSKMLYLSCLSMFSHKKELIPLLFNSISTVSGKVERLISFDIAKRWYLRDIAERMYTSESLIKKKLQDENTCFSKILLASRMSMARRLLELRQIPLHTIAEKCGYSSTSYFINTFRQYYGVTPHQFSQHSPGTFS", "output": "Depending on the conditions (growth phase and medium), acts as a positive or negative regulator of gadA and gadBC. Repression occurs directly or via the repression of the expression of gadX. Activation occurs directly by the binding of GadW to the gadA and gadBC promoters (By similarity)."}]}
+{"id": "function_test_3523", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFELIYPGWLAGILLSFATGPLGSFIIWRRISSFGDTLSHSSILGLAISILFQIDSFYTELFFMSFLAIILVWMEQLLSVSLETILSIISHSSLSLGIICISLMSTSHHIDLSNYLFGDLLLVTVFDLCIIALGSLIVLTILFFRWNSILLLTVNEELAQIDGVNIFYARLTLMLTTAICISIAIKFVGVLLITSLLIIPPATAQIFSNSPEKTIGFSILISIISVTGGIFLSFFYNVPTSPSIVLFSSCVYLLSNIKKLI", "output": "Involved in the high-affinity zinc uptake transport system."}]}
+{"id": "function_test_3524", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSWDDAIDGVDRDTPGGRMPRAWNVAARLRAANDDIVHAQQADGLPAYAELHCLSDFSFLRGASSAEQLFARAQQCGYSALAITDECSLAGIVRGLEASRATGVRLIVGSEFTLVDGTRFVLLVENAHGYPQLCGLITTARRAASKGAYRLDRAEVQAQFRDVAPGVFALWLPGAQPQAEQGAWLQQVFGERAFLAVELHREQDDVARLHVLQALAQQLGMTALASGDVHMAQRRERIVQDTLTAIRHTLPLAECGAHLFRNGERHLRTRRALGNIYPDALLQATVELAQRCTFDISKISYTYPRELVPEGHTPTSYLRQLTEAGIRRRWPGGITAKVREDIEKELALIALKKYEAFFLTVQDVVRFAREQNILCQGRGSSANSAVCYALGITAVNPDETRLLMARFLSEKRDEPPDIDVDFEHERREEVLQYVYSKYGRERAALAATVICYRGKSAVRDVAKAFGLPPDQIALLANCYGWGNGETPMDQRIEEAGFDLANPLINKILAVTEHLRDHPRHLSQHVGGFVISDEPLSLLVPVENAAMANRTIIQWDKDDLETMKLLKVDCLALGMLTCIRKTLDLVRGHRGRNYSIATLPGGDAPTYKMIQRADTVGVFQIESRAQMAMLPRLKPAAFYDLVIEVAIVRPGPIQGDMVHPYLRRRQGREEVNYPSPAVEDILKPTLGVPLFQEQVMELLMHAADYSEDEADNLRRSMAAWRRGGDMEQHRTRVRERMQGKGYASSFIDQIFEQIKGFGSYGFPQSHAASFAKLVYASCWLKRHEPAAFACGLLNAQPMGFYSASQIVQDARRGSPERERVEVLPVDVLHSDWDNTLVGGRPWRSAADPGEQPAIRLGMRQVAGLSQVVAQRIVAARTQRAFADIGDLCLRAALDEKARLALAEAGALQGMVGNRNAARWAMAGVEARCPLLPGSPEERPVEFEAPRAGEEILADYRSVGLSLRQHPMALLRPQMRQRRILGLRELQGRRHGSGVHVAGLVTQRQRPATAKGTIFVTLEDEQGMINVIVWSHLALRRRRALLESRLLAVRGRWERVDGVEHLIAGDLYDLSNLLGDMQLPSRDFH", "output": "DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase."}]}
+{"id": "function_test_3525", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIILETRSLKYSYPDGTAAVQDINIEIKKGKKVAFVGQNGSGKSTLFLLLNGTLKPQEGEILFHGVPFKYDSKSLREIRKSVGIVFQNSDDQIFAPTVYQDVAFGPANLGYSKERVDACVQSALEYVGLIRLKDRPPHHLSGGQKKRVAIAGVMAMEPEVIILDEPLSNLDPVGADEIMDLLNEFNHFGSTIIISTHDVDLAYRWSDYVFLMSNSKLIGQGTPAEVFKEQELLKKVGLRQPTTLEIYHEIERRGLAYGRNSPKTIPDLVNTLKPLDLMWVDVAPGVREGDNLNIGVMYGEYATQSPYEAINATVLHIHPNGRAIVELKRKGIKAGGVLLYDTDKYSPDEVRQIIKEGEIAFVGAMGKKSKTLAEQDGIRLDVTSGVIDKSILMALCGKRCLILTAGGMVDHALKRTREYVDKSGIEFTVGVVNRDGGCKWLEETEGSPEKLKT", "output": "Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity)."}]}
+{"id": "function_test_3526", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLKRSLLFLTVLLLLFSFSSITNEVSASSSFDKGKYKKGDDASYFEPTGPYLMVNVTGVDGKGNELLSPHYVEFPIKPGTTLTKEKIEYYVEWALDATAYKEFRVVELDPSAKIEVTYYDKNKKKEETKSFPITEKGFVVPDLSEHIKNPGFNLITKVIIEKK", "output": "Potent plasminogen activator that converts plasminogen into plasmin. It forms a 1:1 complex with plasmin, which in turn activates other plasminogen molecules (By similarity)."}]}
+{"id": "function_test_3527", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKTCITKGIVTVSLTAILLSCSSTWAAGKGGVGLAATRLVYSEGEEQISLGVRNTSPDVPYLIQSWVMTPDNKKSADFIITPPLFVLNPANENLLRIMYIGAPLAKDRETLFFTSVRAVPSTTKREEGNTLKIATQSVIKLFWRPKGLAYPLGEAPAKLRCTSSADMVTVSNPTPYFITLTDLKIGGKLVKNQMISPFDKYQFSLPKGAKNSSVTYRTINDYGAETPQLNCKS", "output": "Part of the elfADCG fimbrial operon, which could be required for adherence to host epithelial cells. Could be required for the biogenesis of the ElfA fimbriae."}]}
+{"id": "function_test_3528", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSWIILVIAGLLEVVWAVGLKYTHGFSRLTPSVITVTAMIVSMALLAWAMKSLPVGTAYAVWTGIGAVGAAITGIVLLGESANPMRLASLALIVLGIIGLKLSTH", "output": "Guanidinium ion exporter. Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons."}]}
+{"id": "function_test_3529", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRKFLKSAIEYLAKDLDLDKELLEQIQYVVIVLTFEFIKCISVILIAGILGYFKESLIVILSMCFIKPFIGGYHEDSQLKCFIATLIITTSIIMLVTFNKLNLFSIVILNLFSIFSIYNKAPVIDSRFPLTKEHLIKKNKILSVTNSSILFLITLIFFKISWISQTITWTLLIQTLLLFNKYKREDS", "output": "May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor."}]}
+{"id": "function_test_3530", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEDYILKVEELNYNYSDGTHALKGINMNIKRGEVTAILGGNGVGKSTLFQNFNGILKPSSGRILFDNKPIDYSRKGIMKLRESIGIVFQDPDNQLFSASVYQDVSFGAVNMKLSEDEIRKRVDNALKRTSIEHLKNKPTHCLSFGQKKRVAIAGVLVMEPKVLILDEPTAGLDPMGVSEIMKLLVEMQKELGITIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVFAEKEVIRKVNLRLPRIGHLMEILKEKDGFVFDELDLTIGQARKTINSWKNKIFND", "output": "Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity)."}]}
+{"id": "function_test_3531", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNTVGTPLLWGGFAVVVVIMLSIDLLLQGRRGAHAMSMKQAAGWSILWVTLSLLFNAAFWWYLAETQGREVADPQALAFLTGYLIEKSLAVDNVFVWLMLFSYFSVPPALQRRVLVYGVLGAIVLRTIMIFAGTWLITQFEWLLYVFGAFLLFTGVKMALAKEDESGIGEKPMVRWLRGHLRMTDTIENEHFFVRKNGLLYATPLLLVLIMVEFSDVIFAVDSIPAIFAVTTDPFIVLTSNLFAILGLRAMYFLLSGVAERFSMLKYGLAVILVFIGIKMLIVDFYHIPIAISLGVVFGILTITLVINTWVNHQRDKKLRAQ", "output": "Has been proposed to be a redox modulator."}]}
+{"id": "function_test_3532", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MARYFRRRKFCRFTAEGVVEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARCIKRARYLSLLPYTDRHQ", "output": "Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit."}]}
+{"id": "function_test_3533", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEMLRRNFFRLLMVLVAGCGLIASPANALVEININKGNVEPLPIAITDFLQGELAQKISGVIAADLKRSGLFAPIDKGAFIEKISNPDATPRFEDWKVINAQALVIGRVTQEGDGRLKAEFRLWDTFAGQQMLGQQFYTQPENWRRVAHIIADAIYERITGEKGYFDTRIVYVAESGPKNARKRQLAIMDQDGANSRALTNSNDIVLTPRFSPNRQEITYMSFENQQPRVYLLQLETGQREVVGNFPGMTFAPRFSPDGQRVIMSLQQEGNANIYTMDLRSRTTTRLTNTAAIDTSPSYSPDGSRIVFESDRGGKQQLYVMGADGSGQTRISFGDGSYSTPVWSPRGDLIAFTKQSGGKFSIGVMKPDGSGERILTTGFHNEGPTWAPNGRVLMFFRQNAGAGGPQLYSIDLTGYNEQLVQTQGFASDPAWSPLME", "output": "Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity."}]}
+{"id": "function_test_3534", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNNKRHSTNEQLSLDEINNTIKFDHRSSNKQKFLSFLGPGLLVAVGYMDPGNWITSMQGGAQYGYTLLFVILISSLSAMLLQSMTVRLGIATGMDLAQMTRHYLSRPIAIIFWIIAELAIIATDIAEVIGSAIALNLLFNIPLIVGALITVLDVFLLLFIMKYGFRKIEAIVGTFIFTVLFIFIFEVYISSPQLNAVLNGFIPHSEIITNNGILYIALGIIGATIMPHNLYLHSSIVQSRTYSRHNNEEKAQAIKFATIDSNIQLSIAFVVNCLLLVLGASLFFNSNADDLGGFYDLYHALKTEPVLGATMGAIMSTLFAVALLASGQNSTITGTLAGQIVMEGFLRLHIPNWLRRLITRSLAVIPVIVCLIIFKGNAAKIEQLLVFSQVFLSIALPFCLIPLQLATSNKDLMGPFYNKTWVNIISWTLIIILSILNVYLIVQTFQELQS", "output": "H(+)-stimulated, divalent metal cation uptake system."}]}
+{"id": "function_test_3535", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAEDGLPKIYSHPPTESSKTPTAATIFFGADNAIPKSETTITSEGDHVTSVNEYVLESDFSTTADNKLTPTKEKLRSEDDMGTDFIKSTTHLQKEITSLTGTANSITRDSITENFMTVKIGNISSPVTTVSLIDFSTDIAKEDILLDTIDTGDAEILITSEVSGTLKDSSAGVADTPAFPRIKDEADMNNYNSSIKSNVPADEAIQVTDSIIPEAEIPPAPEVNFTTIPDITALEEEKMTKIDLSVLEDDTSAVATLTDSDEEKFITVFELTTSAEKDKDNQEDTLLTDEESPEGANMWMERETATEAETHSVLLTAVESRYDFVVPASIATNLVEDSSTEEELSETDRTETVPKITEPFSGTSSVLDTPDYKEDTSTTETDIFELLKEEPDEFMI", "output": "Calcium-binding protein (By similarity). Essential for maintaining the structural integrity of the sperm flagella (By similarity)."}]}
+{"id": "function_test_3536", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNKYETLFILNPSLDEEGINTNVEKFKSVITNGGGEVENVDLWGKRKLAYEIDKVNEGIYVLVNFQSDAQLPKELDRVFRISDSIIRHLIISLEK", "output": "Binds together with S18 to 16S ribosomal RNA."}]}
+{"id": "function_test_3537", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNKINESQLEMDEISKKELHESIIESLLFVSGEPLKLKQISAILECTTKRAQEVLNNMMLKYNDNCRGVKLININDSYQLVTKNENSDYVRKLLKTNTRQALSQAALETLAIIAYKQPITRIDVDEIRGVKSDRAILTLQEKKLIQECGRLDVPGRPILYETTDEFLKNFNLGNIDELPPMEQIASELDEVAVDEEVKEGTE", "output": "Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves."}]}
+{"id": "function_test_3538", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAISQERKNEIIKEYRVHETDTGSPEVQIAVLTAEINAVNEHLRTHKKDHHSRRGLLKMVGRRRHLLNYLRSKDIQRYRELIKSLGIRR", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.; "}]}
+{"id": "function_test_3539", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRVIDASGAIYGRLSAYVAKRLLEGEEITIVNASKAVITGNKEFIIEKFKERLDIGSVRKGPYYPKTPENILRRSIGDMLPKKITKGKEALARCRVYRNTPPDIEKEKVEKVDGVVTDKVSGIITLGDLSKELGGY", "output": "This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly."}]}
+{"id": "function_test_3540", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSNLKHCSNCKHNGLITESNHEFCIFCQSIFQLSNKVSKKSNFHVSNKLIHLRNVLRRLLSNQCSSDVIVELKSVMTKNNISSTDIDANFVSSFLKANEKINKKDYKLVFEIINHIKEEKLNLDTSKINEVIEIFKHLVFFCQENTPSKTINYSFFLDKIFSLTSVTNNLKPQTVKNYTKNNSNQLVWENFLDYMKKKKINTSVYDYGHEYVFVDYGFTTCSLEV", "output": "Acts with RNA polymerase to initiate transcription from late gene promoters."}]}
+{"id": "function_test_3541", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGCYSMGFVGRKAGMSRVFLEDGCSIPVTLIEATANRVVQIKTSDVDGYDAVQVTVGSRRSVLVNKPESGHFAKAKVEAGRGLWEFRVEKTQLGSYSVGSEVGLSIFAVGQKVDIQGITKGKGFQGTIKRHNFRMGDATHGNSLSHRAPGSLGQRQTPGRVFPGKKMSGHMGAVRQSVQNLEVVKIDVERCLIAVRGAIPGASGGDVLIRSASKI", "output": "One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit."}]}
+{"id": "function_test_3542", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKKEHRIKRSDEFSRVFNEGFSVANRQFVIYVLPKEGQDFFRVGLSVSKKIGNAVTRNRVKRLIRTFFQEHEQAISGERDYVIIARKPAADMTYEQVKGSLWHVCKKAKIIQPKVRAHK", "output": "RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme."}]}
+{"id": "function_test_3543", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPRLKLLHGFHAITARLRAFPATVNEVWYDPARQDARMRAFLHLAASANARLIAADASRLNALSGEKRHQGVVARVTEATRAHSLETLLDTIEGQPLLLALDGVTDPHNLGACLRVADGAGAHAVIAPRRRAAGLTAAAAKAANGAAETVPYLTVINLARALRALKNAGIQVIGTADDATTSLFDIQLDGALALVMGAEGAGMRRLTREACDEVVRIPLAGHVQSLNVSVASGICLFEAVRQRLKRL", "output": "Specifically methylates the ribose of guanosine 2251 in 23S rRNA."}]}
+{"id": "function_test_3544", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEKFEGYSEKQKSRQQYFVYPLLFQEYIYAFAHDYGLNGSEPVEIIGCNNKKFSSLLVKRLIIRMYQQNFWINSVNHPNQDRLLDHSNYFYSEFYSQILSEGFAIVVEIPFSLGELSCPEEKEIPKFQNLQSIHSIFPFLEDKFLHLHYLSHLEIPYPIHLEILVQLLEYRIQDVPSLHLLRFFLNYYSNWNSLITSMKSIFLLKKENKRLFRFLYNSYVSEYEFFLLFLRKQSSCLRLTSSGTFLERIHFSRKMEHFGVMYPGFFRKTIWFFMDPLMHYARYQGKAILASKGTLLLKKKWKSYLVNFSQYFFSFWTQPQRIRINQLTNSCFDFLGYLSSVPINTLLVRNQMLENSFLIDTRMKKFDTTVPATPLIGSLSKAQFCTGSGHPISKPVWTDLSDWDILDRFGRISRNLFHYHSGSSKKRTLYRLKYILRLSCARTLARKHKSTVRTFMQRLGSVFLEEFFTEEEQVFSLMFTKTTHFSFHGSHSERIWYLDIIRINDLVNPLTLN", "output": "Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns."}]}
+{"id": "function_test_3545", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRLIRMLLATALTFSMIPAHADSKDVARLTQLLEKSQTLTARFSQLTLDGGGTQLQETTGEMALQRPGLFNWHTDAPQEQLMVSDGKKVSLWDPDLEQVTIKKLDQRLTQTPALLLSGDVSKISESFDITAKEAGGVIDFTLKPKTKDTLFDSLRLSFRNGIINDMQLIDSVGQRTNILFTGVKANESIAASKFQFQIPKGADVIQE", "output": "Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)."}]}
+{"id": "function_test_3546", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MELNAFTILQIAVFIAVGYHANTHSPVAGSEVQKLTSDPNDDIDVSYCGMNCTVVNGKSDECSENCKCLHEGDDPKGICVAITYFGDWGDPNDDPKINEATPQTQIFEKKRK", "output": "Salivary chemokine-binding protein which binds to host chemokine CXCL8."}]}
+{"id": "function_test_3547", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSEVVIICSSSDPASSNIASRLLELAEWDEEGTLRFHRSYCMLCIEGELVGLRNLEDMLDRIGLSPRLIIFASRHISKEAVPWLGGHFTGVVREGSFELSRPAPYALKKLLMALQRHAPSTFRLSAEATHHGPVDLRTPSLFAEIGSCEQHWIDPAAGAAVARAILELESYEAHADETVLLGIGGGHYVQRQTELILSRPVAFGHMFSKYQASMLNVEAIKKAADLSGASGVYLDGKSFRSDERRRLEEIAASLDLNVMGIKEVRSL", "output": "D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo."}]}
+{"id": "function_test_3548", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRILLTNDDGVYAKGIETLYLALIEEHDVTVVAPETEQSAVGHAITWLDPLRVKPVHRNGHFFGHALTGTPADCVKIAVAELMSPPPDMVVSGVNMGANVGVNVIYSGTVSAATEAAVMGIPSMAVSIDSFQPTDFSAVTEFVPRLLRIVAKEGLPPGVCLNVNVPNLPADRIRGVKVTRQGHMKMVERYDRRIDPRGHVYYWLTNSALLRDDDPATDSLALARDYISVTPIHHDLTHYEMIDTLGKWNL", "output": "Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates."}]}
+{"id": "function_test_3549", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSKTVEPACLVPVGKVTRTHGIRGALKIFPYGESLAAQAAGERFFLRSKNGGYCTLTLIGLRAQGRMLVCGFEEIKDVNGAQPFVGEEIFLPEDRLPPVSEGEYYHYRLIGLDIVTLDGESLGVLRKIIETGGNDVYVAEREGREILIPAIEDVIREIDLERKRMVVDLPEGLVDA", "output": "An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes."}]}
+{"id": "function_test_3550", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRMVCMSDVNDELDGSPILEEVLGDALGKLKVFHVKLAAEGEPRGLIGPRDVGIIWERHILNSAAIVPFIREATAKRQFKTVADIGSGGGFPGIVAAACLPDHQFTLVEPMERRIEWLHECVDEMGLDNVSIVRSRANAVIEAVRGSNGGRKGRGEDAVDLDGNPIPVRHPFAVVTCRAVAPMTKLSGWTLPLLDKGGRLVALKGRSAQEEIVKATKEISKNGGIHPRVVEAEVGPGLEPTHVLMVDER", "output": "Specifically methylates the N7 position of a guanine in 16S rRNA."}]}
+{"id": "function_test_3551", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPSHYYLIIPASGVGVRMHPEKDGLNEQPKQYLKLDNGLTILDQTLKTLLSINQIKSCVIAIKNKDHLFAKSAFNNHPKLLTIVTGGKERMYSVLNALKALIDFAKDDDWVLVHDSVRPCVKASEIINLMKQLKHHATGGLLATKVVDTIKQADNNIINTTIDRSNLWQAQTPQMYRFSVLLKALNTAIKDGINITDETSAIEHLGLESILVKSSKSNIKVTNPEDLILANFYLNQHQK", "output": "Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP)."}]}
+{"id": "function_test_3552", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFGKGGMGNLMKQAQMMQEKMAKMQEEIARMEVTGESGAGLVKVTMTGTHNVRKVEIDPSLLEDDKELLEDLVAAACNDAARRVEENQKTKMAEVTGGMQLPPGMKMPF", "output": "Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection."}]}
+{"id": "function_test_3553", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRTVGVEEEFLLVDADRSRPIPAASRALRVATEWGVAGGQVGAGALVHELQEQQLEIYTAPQVRMASLETELRAWRAAAAAAAAAVGARLVASATSPVAVEPHRVRSPRYDRMAERFGIVTDEQLTCGCHVHVAVGSTAEAVGVLDRIRVWLPALLALSANSPFWQGRDTGYASFRIQALGRWPLSGPTELFGTAAAYQELVERVLAAQVVLDQGMLYFDARASHRFPTVEIRVADVCLDVRDTVLIAALCRALVETSAARWAAGEAPPQVPAVLLRLATWHASRWGVSADLLDPMTARPLPAAEVVGRLVEHARPALRRSGDDGLVADGIARILEHGNGATWQRDVFAGSGRLDEVVSALALVTSGGA", "output": "ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity."}]}
+{"id": "function_test_3554", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEVILLEKVANLGSLGDKVKVKAGYGRNFLLPYGKAVPATEANVKAFEERRAELEKAAAEKLAAAQARAEALEGASFTITSKAGEEGKLFGSIGVRDIADAVSTGGTEVEKSEVRLPEGPIRVTGEYDIELQLHTDVEVTIKLAVVAE", "output": "Binds to the 23S rRNA."}]}
+{"id": "function_test_3555", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MFADSAVACVISALRAVGVDSPLMSELVPRLLFVHAHPDDETLTTGGTIAHYVRRGADVRVVTCTLGEEGEVIGEQYAQLAVDHADQLGGYRIAELTAALAALGVDAPHFLGGPGHWRDSGMADTPARHQPRFVDADMAEAAGLLAAILDDFRPHVVVTYDPDGGYGHPDHVQTHRVTTAAVERAQWQVPKFYWTVMSRSGMGDAFAVARDVPEEWLQVSVDDVPFLYTDDRIDAVVDVSDSIEAKVAAMRAHATQISVAANGQSCALSNNIAMPIPGVEHYVLVSGAPGPRDARGWETDLLAGVNLA", "output": "Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway."}]}
+{"id": "function_test_3556", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIQTESRLEVADNTGAREVMCIKVLGGSKRRYASIGDIIKVSVKEATPRGRVKKGEIYNAVVVRTAKGVRRQDGSLIKFDGNAAVLLNNKLEPIGTRIFGPVTRELRSERFMKIVSLAPEVL", "output": "Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome."}]}
+{"id": "function_test_3557", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIDIGLSKMALIGAVALIVIGPEKLPRVARTVGTLLGKAQRYVADVKAEVNRSMELDELKKMKDTVESAAREVHDSIQTSASAFEKDWAEAIDSAAPLPGSTATVPAPEYKHPGKRWRLKRSALPQWYKARSGVRSKALSGAARVARYRPGKSR", "output": "Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation."}]}
+{"id": "function_test_3558", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAIAEWRQQLKLGEVSARELIDHQLARIAVVDPTLHAFLDVTAERARADADRIDEALAAGESLPPLAGVPLAIKDNLCTKGIRTTCSSRMLETFVPPYESTVTERLWQAGAVLLGKTNLDEFAMGSSTETSAFGATSNPWDISRVPGGSSGGSAAAVAAGECMAALGSDTGGSIRQPASFCGVVGLKPTYGRVSRWGLVAFASSLDQVGPFTTNVADAAELLQVIAGSDPRDSTCLNVAVPDYCSALSQPMSGVRIGLIRECFDQNGLDAQVKSTVLEAAEKLQSLGAELVEVSCPRFSDGIATYYVIAPSEASANLARYDGVKYGYRAEGADALAAMTARSRAEGFGSEVQRRILIGTYALSAGYMDAYYKKAQQVRTLIRQDFDAAFQTVDVLLTPTSPTTAFQVGAHADDPLAMYLADLLTIPANLAGLPAISLPCGFDDDGLPIGVQLIANVLEESRLLQVAFHYEQSANVMTNHPQGNFIP", "output": "Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)."}]}
+{"id": "function_test_3559", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEPVGVSHNTPEMDPPRNIQTPELPESGSVKDKIGKFSAYQQQPSGLKDAFGKTPTSIGANRSRTPQQIAAQLAAGRSTPGEITATHTGVSRTQGSRPTTSKRSDDNEGPPLLAPKPVWATSANTASVNKLLRSEADLPIRDKSIQRRPVAQISPIEAARLAAKKPRPPPVPRKPAAVATGPTSVPINVHSKGPESPEPTSKNHSSRHLEDTTIPFKAPPALPPRTGASSVPRKDLTNHRRLLDTNHGSRRRPSTPGTASLYTTSLSNSTTSLLDSSSGLDEGALSDAVVASSRASVRASQERKVPPPPPPERRARSRSLKQFPHTAKGEHTDSSSPSTHLRQTLREPTKIAENDEGYQRHKHLIRKHPHKHHEGDRRRWRSEITEKERKRYEGVWAANKGLLLPPAHLRVPEAYPPESSEMVVNLVAADIWSRSRLPRHVLAQVWDLVDGQHIGLLTREEFVVGMWLIDQQLKGHKLPPRVPASVWGSAKRISGVHIHGLPPA", "output": "Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity)."}]}
+{"id": "function_test_3560", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSRDYKGKKIVIYPQYIDSSIPRSRGRRIPRNIAIPKPRIEEIIEAAEELGLNPKYEESAYPKHWWIKGRIVVDKVGSKLNTLKLIAQKIKDLRK", "output": "Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP."}]}
+{"id": "function_test_3561", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVMLDLLSNALTAIKNAEAMGKRQVVIWPVNKLIYYTLRVLQRYGYVGEIEYIDDGRGGKYVVQLLGKINDIGAIRPRFPVKYREIVEWEQKYLPARQIGILVISTSQGVMSHLEAKEKKIGGVLLAYVY", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit."}]}
+{"id": "function_test_3562", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MARRRKYEGLNPFVAAGLIKFSEEGELEKIKLSPKAAIAISLAIIAAILALNLLLPPP", "output": "Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex."}]}
+{"id": "function_test_3563", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAEENQVAAPEEAQTPFELQIQRIYIKDVSFEAPNLPTIFHQEWKPQLGFELDTETKQLDEDLYEVVLHINVSTTLEDSGDTAFICEVKQAGVFTIKGIEGIQLAHCLASQCPNVLYPYARELISSLVNRGTFPALNLSPVNFDALFMDYLQRQEAEQNAEAPAVN", "output": "One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA."}]}
+{"id": "function_test_3564", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSLTNEQLIEAIASKSVSEIVELIAAMEEKFGVSAAAAVAAAPAAGAAAAEEKTEFDVILAEAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGISKPEAEALKKELEEAGAKVEIK", "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation."}]}
+{"id": "function_test_3565", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTEPNNTDLLDLATPYALHAVSIDERFEIDRWLATAPPEVADAFTDEVRSVQETMAVLSAATATEPPAHLRDNVLAMVADDPVRDLGSARRRRGGESRWRTAVLAAAAVAVVGLGALGVGLALRPAVSPTTADQVFAAPDVQTVSGPIPGGGTATVVFSKERDAGVLVMNDVAPPKPGTVYQMWLVGSDGPHSAGTMDDKAISPSTTAVLSDIGTSQALAFTVEPPGGSQRPTSPAFAELPLT", "output": "An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor (By similarity)."}]}
+{"id": "function_test_3566", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAKAKFERDKPHVNIGTIGHVDHGKTTLTAAITKVLHDKHPELNPFTPFDEIDKAPEEKQRGITIQIAHVEYQTEKRHYAHVDAPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKADMVDDEEIIELVEMEVRELLSAQEFPGDDVPVVRVSALKALEGDAEWGDKIMELLDAVDENVPDPERETDKPFLMPIEDVFSITGRGTVVTGRIERGVINVNEEVEMVGIKEKPLKTTVTGVEMFRKLLDQGQAGDNVGLLIRGIKREEVERGMVVVKPGTTTPHTEFEAQVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEGTEMVMPGDNTEMSVQLIQPIAMDEGLRFAIREGGRTVGAGRVTKIHK", "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."}]}
+{"id": "function_test_3567", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQTRKTLSWIKEEITRSISVSLMIYIITGAYISNAYPIFAQQGYENPREATGRIVCANCHLANKPVGIEVPQAVLPDTVFEAVVRIPYDMQLKQVLANGKKGALNVGAVLILPEGFELAPPDRISPEMKEKIGNLSFQSYRPAKKNILVIGPVPGQKYSEITFPILSPDPAAKKDAHFLKYPIYVGGNRGRGQIYPDGSKSNNTVYNATAAGIVSKIIRKEKGGYEITITDAPEGRQVIDSIPPGPELLVSEGESIKLDQPLTSNPNVGGFGQGDAEIVLQDPLRVQGLLFFLASVILAQIFLVLKKKQFEKVQLSEMNF", "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions."}]}
+{"id": "function_test_3568", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIQSTGVTHTDKSAQENPVKYRDNFTPVIITGMSGAGLSTAARVLEDLGWYVAHNIPPQIILELIDMCAREDSPVDKVAVVCDVRSREFRGSLTQVVSELRDKQLDPTVLFLEARDEVLIKRFDNVRRTHPLQGSQTLQVGIERERTVLSPVKEDASVVIDTSDLSVHDLRRAIESSFRTIATRTQHVTIESFGFKHGSPRDADFVVDVRFLPNPFWVPELRPFRGVDKPVSDYVLSQKGAEEFLNNFVDMLKDMLPGYRHEGKNFITIGVGCTGGHHRSVAVSEELAKRIADQTTLDVSVVHRDINRH", "output": "Displays ATPase and GTPase activities."}]}
+{"id": "function_test_3569", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSVTIDDVTYIAELARLRFSDDEALKMTDELNTILHYVDTLNEVDTEGVLPLSNIHDQKNVLRADEEHEPIANAAALSNAPDSQDRFFRVPKVLG", "output": "Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)."}]}
+{"id": "function_test_3570", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTQAAEHITVLLHEAVEGLAIKPDGIYVDGTFGRGGHSRLILQHLGPNGRLIAIDRDPQAIAEAAKIQDPRFEIVHGPFSGIVSYLDERGLLGKVDGFLLDLGVSSPQLDDAERGFSFMKDGPLDMRMDPTSGQSAAQWLARADVDDIAWVLKTFGEERFAKKIARAIVHDRVTEPYVRTRQLAEMIARVNPSKEKGKHAATRSFQAIRIYINSELDEIETALNGALQALAPEGRLSVISFHSLEDRLVKHFIRKHEKGPEVPRGIPLTEAQLAGGRKLKSVGKALKPSEHEVTENSRSRSSVLRVAQRLAE", "output": "Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA."}]}
+{"id": "function_test_3571", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIDDDGYRPNVGIVICNRQGEVLWARRYGQHSWQFPQGGINPGETPEQAMYRELFEEVGLNKKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQRWFLLQLMCNEAEINMQRSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFAATVMPVQEVAPPRVPPAYRRKRG", "output": "Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage."}]}
+{"id": "function_test_3572", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MITGIQITKAANDDLLNSFWLLDSEKGEARCVVAKAGFAEDQIVPVNKLGEIEYREIPMEIQPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTASL", "output": "Acts as a radical domain for damaged PFL and possibly other radical proteins."}]}
+{"id": "function_test_3573", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLTPVVSYSTVREVKGPLIVIEKTRGVSYGEIGEVVGPDGEPRRVQVIEVGTDYAVAQVLGGTLGLPARGSTVRFYGKTLKIPVSEQLIGRILDGKGQPRDHMPLPPPEDFRDVNGEPLNPYSREYPEEPIETGISAIDGLYTLVRGQKLPIFSGTGLPHNLMAAQVVRQSTVRGSEEGFAVVFVGVGIKTEEALFFMDEFRKTGALRRAVAVLNLASDPVAERVLAPRVGLTIAEYLAWQLGYHVLVVITDMTNYCEGLRELSSGRGELPGRRGYPGYMYTDLATIYERAGKAHGRKGSVTQFPILTMPHDDITHPIPDLTGYITEGQLVLSRAMWGKGIYPPFDVIMSLSRLAKDAIGEGKTREDHKDVANTLIAAYSKALEIRNLATLVGERNLGWRERRYLRFADAFEQKFIKQGYYERRSFEETLDIGWDVLSILPEDELTNARPQITQKFYRRHVYESVQL", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit."}]}
+{"id": "function_test_3574", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEKFTIHTGTAVPLRLSNVDTDQIIPAVHLKRVTRTGFADALFSSWREDQAFVLNDESYSGASILVAGPEFGTGSSREHAVWALRDWGFRVVIAPRFGDIFRGNALKGGLLPVELELKAIEEIWGRIEADPSTSITVDLAARQVQVGGVNWGFPLDEFSRWRLMEGLDDIGLTLRHEPLIGAFEASRQPFLPTIA", "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."}]}
+{"id": "function_test_3575", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSERDKLYHVLLDRLYAKLPKKDLASETQTLPTLSIINVGNTTIIRNFSEYCDRIRREDKICMRYLLKELAAAGSISENGQLMIQGKFSNAIVNTFMDRFLKTYVQCSTCKSLDTVLVKDKKIWYIQCLACGAKNPVKPL", "output": "eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA."}]}
+{"id": "function_test_3576", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MHMRLVVIAIGRLKQGPERQLAERYRERFDDIGRKLGFRGLDIHEIPESRARDAATRMAEEAAAIAAAIPDNSMLVCLDERGHNIDSATFAGHIGRWRDEGVAATAFVIGGADGLSPELRRKAKLGVAFGAATWPHQIVRVLLLEQIYRTATILAGHPYHRA", "output": "Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA."}]}
+{"id": "function_test_3577", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSILSLVTAPDPILKKVSSPVDTVNDSIRQLIDDMLETMYHNHGVGLAAPQVAVSKRIIVLDLSKVDIEEDNITNSEYKYPLFMVNPIVKAISNQTVTAKEGCLSLPKQAIEVSRYHEIQVTYLDYYNKLKTLNAAGWLARAIQHEVDHLDGILLVDYLSNLKKEATLNTLSKIKDAAYDK", "output": "Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions."}]}
+{"id": "function_test_3578", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSAGQSTSQAAALAAFKSISTHPKTDQNPSKVHQSPERNVKRNPSGRLTNSRNATAVNAINRSPPKAPQKPQLSVVTASGHETKKNVENNRQRSSSPSPLYRTTTPKQMTSPSTSSASLPSNMIKSVKDSIEAKRHASEAKRLAQENQPSDMLTKIRQSINDRTRNIPNQAKVNERNMATINGIRESIESKRITTQANSSMIVLDTSSNSPYNFAPPDELRSPYEAHSPNYSYSSFESVPSAYSNPDSNIDLHDRGPETPSIVVDSPFNSQYDLSSPREDSDIDQERRNTAPILIPPSSNACARSANSAGSADDARSHLSSLKYQVEKEKNEDKNKKPKRKPPPELKPTTDLDGAFFSDSSSLNPGSSRSSLDAGSYSTDNESMGRNRMGSNDSDLSKPIKLPQYPELDTSSTKFKIRKRHGESNQNVGKMTESGSESDFEYPKATVPVSRATAPPLVHQKSQHVQLKTTMRDSKKKKKDKKSFDVDKPWKNHSDLDRISEADRKRYEGVWASNRGTYFNYVVTRINGIDYGSGGGSEQKIIVDEEDSMKAARLSAKQQADTVSGANGGYQSAEFHNITNAEISQLIHSSVVERIWERSRLPSETLRDIWELVDYRKDGTLNKPEFLVGMWLVDQCLYGRKLTKKVPASVWESLEGIGVSVKKKGKR", "output": "Positive regulator of phosphatidylinositol 4,5-bisphosphate turnover and negatively regulates signaling through the cell integrity pathway. Involved in rDNA silencing (By similarity)."}]}
+{"id": "function_test_3579", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGASPVQLLIVLFIAVLVFGGKRLRTLGSDVGAAIKGFKEAMKEEPTEPEKLEQQPPVIEVVATQKEKTKG", "output": "Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system."}]}
+{"id": "function_test_3580", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIQGIQITKAANDDLLNSIWLLDSEKNEARCVAALKGFEADQVVSINDLGQFESREVAIEAAPRIEGGQHLNVNVLKRETLEDAVAHPEKYPQLTIRVSGYAVRFNSLTAEQQRDVIARTFTESL", "output": "Acts as a radical domain for damaged PFL and possibly other radical proteins."}]}
+{"id": "function_test_3581", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLKRINLLREFSIPLLAGVLTALVWANVAPDSYHKFNHDHFLGPLSFHFVTNDIFMAFFFAIAAVEITQSCLPGGDMSPLNKALNPLLATAGGVVGPVGVYLALNSLVGSSAFTNGWGIPTATDIAFAWLAARLIFGKNHPVIAFLLLLAIADDAIGLVIIAVFYPDPVLPVAPPWLMLTAAGMLIAFILRRKQVKSYWPYLLFGGVPSWFGLFKAHLHPALALVFIIPFLPHPTREVKHMFEEDPKDYSPLARFEHEWKIIVDFGLFMFGLANAGVGFSAMNTVTWLVFCALLFGKVTGIFVFALLGEKLGFPLPQGMGRRHLLVAGIIAGIGFTVALFVAGEAFTDPVVQGAAKMGAILSIAVFPVAMAAAKLLGIRKRGHSSS", "output": "Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons."}]}
+{"id": "function_test_3582", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIYIDNRQNKIKVNEELENKIKEIIDYALKEEKVNIDYEISVVFIDNNSIKEINKDYRNIDKATDVLSFPMLDYEDGEVFKDIYLNYEFDESDLDEGNLVLGDIALSLEKAEEQSKEFGHSFLRETCYLTIHSVLHLLGYDHMEEDEKVIMRQREEEILKSFNLHR", "output": "Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA."}]}
+{"id": "function_test_3583", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAIRGHKGLQQLLSMATSVNSFLGPMKSYKFIFDQITHESILTSSSFRLLENLDLTSAIGQLLNETIQAHHKSYKTGTTTLFFMVGAWSSAVQECLHLGIPVSLIVSVMLDGLNSCIGHVHSLQVSLVSQVTSDCTNIKTNGINHSNYSASGDQGNCSSELENNPLPRVSNMRTASEFPVAFHKKPLPLCTGTNLYKTQRRRLFHSRHLAEDLSFFQDVPERPQTTTLNNETLDGLAKGLAHGYQPVMNLVKNAVCLHCAEIKENSLDKSSFNISRLETCSLPGLSEEHTTVSFGYTTLVPTESAAVITHLNGKPLRILLVDGELTESHRHLGFDNPDNVKMVFEHAGNEKHNLEDSWISRAYEKIIQANINLILVRGDVCPFLLKQCIHRNILIVTQVKQNILQAFSECTGAEPVTYLTQINCCSVGNEAFVTLCTRANSIIEVSQKIVISITAKKLNLITATLSSRIPSTMQSIEDQFLTCAYRLHHALQEGNVFYGGGAIELLCIHHLQKLVQESSSSFYAYDNAQFHCLSSWMTESATFYRAAIIGCLAKGWYKYISVLLCNMGGFLSELDAVTFIENELQNISHHSSPIDYVRDQYSKKDLFNDEMGISISHHSLPVYDNVTPKLEAWRRALHLVLTVLQTDAEVITNSATQNQILMSETSNGEYLFL", "output": "Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis."}]}
+{"id": "function_test_3584", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MFKKVDKKASREKRHLRVRKKVFGTAERPRLSVFKSEKNIYAQVIDDINGVTLVAASSLEKDFAAKGGNKEGAKLVGELVAKKAIEKGIDVVVFDRGGYIYHGRIQELAQAAREAGLKF", "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."}]}
+{"id": "function_test_3585", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKNVTDSFVYLVGHCPFAGSFAFNTDILATNPINLSIVLGVLIFFGKGVLNDLLDNRKQRILSTIQNSEELRKKTIEQLERARDRLRKVEIEADEYRINGYSEIEREKTNLINATYDSLERLENYKNETLHFEQQRAINKVRQRVFQEALQGALGTLNSCLNSDLHFRTISANIGILGAMEEITD", "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "}]}
+{"id": "function_test_3586", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MALDSAKKQEIISKFAEHEGDTGSPAVQIALLSERISYLTEHLKEHKKDHSSRLGLLKLVGQRKRLLNYLKRKDYEKYTQVIKELGIRG", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.; "}]}
+{"id": "function_test_3587", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKFNDVYNKHHKIIHHLLKKYNISYNYDEYYQLLLIKMWQLSQIYKPSSKQSLSSFLFTRLNFYLIDLFRQQNQLKDVILCENNSPTLTEQPTYFNEHDLRLQDIFKLLNQRERLWLKLYLEGYKQFEIAEIMSLSLSTIKLIKMSVKRKCQHNFN", "output": "Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Sigma-S contributes to the protection against external stress, thus playing a role in cellular fitness and survival (By similarity)."}]}
+{"id": "function_test_3588", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAQTTTKSNGQLPTPPTNNGAPTVNRKKQKRRAKQAARAAAEQAQGSQMSGGPTSGDVKRQMQELEARFRETGLDEQYDDDEQFDPADENAYYSDEEGDAYSGSYGHDGSSTNGYAIPTTNSSKKQKKKKKSKSSQSDHSNHANHGPNGSSHNHVSLPLPLQSPPSMQRGPGISKEKIWNTSSQEERERIKEFWLSLGEDERKSLVKVEKDAVLKKMKEQQKHSCSCTVCGRKRTAIEEELEVLYDAYYEELEQYANHQGGDGPPPMMPPPRRFGAMSGLQPPNRLPPVFNGQQPSRGRIVEQLGDDEDEEGDEEYSEDDGDEDDFSEEEPEEIPRSHATDFFNFGNSLTVQGGILTVADDLLKNDGKKFIEMMEQLAERRMAREEDAKEQYANANYGHPSNGSMHPHSHGHVHNHPPPPEEDEYDDEEDDEDEYDSQEEDYDEEEMDSMTEEQRMEEGRRMFQIFAARMFEQRVLTAYKEKVAKERQQKLLEELEEESRADSQKKAKRAKDAQKKKEKLLEKKRAMAEEKARKDAEKAAEEASLREIEEKKAEAQRLKREENRKKKEAQKKADEEERVRKESEKQRRLQEQRERQAEQERKQREAKERERKEKEELRRQALEAKEIKEKEAKERKEKHEREKREKEAKVKADKEARELQKREELSAQQAAVQAAQSAAHVSRRANQVPTPKLSHALASPHIPVAIPAVPKAPTPIKLRTNSQQDNYSIPRTPSSKYQSISPNSVTPLPNSPGPIGPPGKTPIQHPLLQHPQATSPIHSALKGPPGIPQSPYAGMQPMPGGFQPGMPMVPPGFGRPHHDPMFGLQQGIGSQFRPLQIPNGGIPPFQPGFNIHHMPQGRGFPMHGPPGFPQHSPNGMGSIGQLFGAPKETPPSQTHSRNQSGSFDGLSSATQAQPIARPTPIGRPSSIVHGTRHSDNFNSGESDETSKHLGSSALLDDTDEPINIGVGARRSSAAPGNPGRQNFLPPPFGMDRSDPASMMSSFNTWGAPPNPFGSSSLPGSNGFGGGWNTSLNMNGSFGMTNYYHSQPRSVAVRLRICGACQNLQNSTQDGWLDIDAIKNEIALSTTVREEPLSERELLDICDTEGNPMNGGGTFEIRSSDGKSQIHFVSDSMSHDFRSAGAPGEIGSPISGGASRNLGPPGRAPIGGF", "output": "May act as a negative regulator of salt tolerance."}]}
+{"id": "function_test_3589", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSLWINGEWRPGRGPGFSKQDPVNLKVVWQGEAADAGQVAEAVAAARQAFPSWARLPFAARQAIVEKFAALLEASKAELTAVIGAETGKPRWEAAGEVTAMINKVAISVKAYHVRTGEQHSDLPDGAATLRHRPHGVLAVFGPYNFPGHLPNGHIVPALLAGNTVVFKPSELTPRSGEAVVKLWQQAGLPAGVLNLVQGGRETGEALSGQADIDGLLFTGSSTTGFHLHRQLAGQPQKILALEMGGNNPLIVDDPRDVDAVVHLTIQSAFITAGQRCTCARRLLVRRGEAGDAFLSRLVTVSQRLIPAAWDAEPQPFLGGLISEQAAQKVHQAWLQRVAAGAVTLLEPRLLQAGTSLLTPGIVDMSDVANVEDEEVFGPLLGVWRYDTFEEAIALANATRFGLSCGLISPEREKFDRLLLEARAGIVNWNKPLTGAASTAPFGGTGASGNHRPGAWYAADYCAWPMASLESPTLTLPASLSPGLDFLAGEAS", "output": "Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate."}]}
+{"id": "function_test_3590", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTKETQSFEEMMQELEQIVQKLDNETVSLEESLDLYQRGMKLSAACDTTLKNAEKKVNDLIKEEAEDVKNDESTDE", "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."}]}
+{"id": "function_test_3591", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSEVETTNDQTPAPKRKDKKPSRSQLRSASRRLALQAVYQWQMNKTAVSEIETQFVIDQDRDMDSCDKVYFRELLQGVTASAKKLDTLFEELLDRPLSELDPIELAVMRIGSYELSQRLDVPYRVAINESVELAKGFGATESHKYVNGILDKLAQRVRREEIAARREANKESNK", "output": "Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons."}]}
+{"id": "function_test_3592", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAITAAQVKELRDRTGAGMMDCKNALTETNGDMELAIDNMRKSGAAKAAKKAGNIAADGTILIKNGEGFAALLEVNCQTDFVAKDSNFLAFANAVLDAAAASKVTLEDLKAQFEDARVALVTKIGENINIRRVEYIDGANLSSYRHGERIGVVVAGEADEETLKHIAMHVAASKPEYVNPEDVPAEIVAREQALQIEMSMNEGKSAEIAEKMVLGRMKKFTGEISLTGQAYIMEPKKTVGEILKEKGAKVTNFIRLEVGEGIEKKEEDFAAEVAAQIAASKKA", "output": "Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome."}]}
+{"id": "function_test_3593", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNDETAPTNKSQEKAELRRGWTTGACATAATKAALTALITGEFPDPVGIILPKGEVPYFQLAYEGLGDGYAMAGIVKDAGDDPDVTHGATIISTVFPAPPGTGVVFRAGEGVGTVTRPGLQIPPGEAAINPVPRRMMTEICEQICAEYGLPADIVITISVPGGEEIAKKTWNPRLGIVGGISILGTTGVVHPFSCSAWIHSIHRGIDVARAAGQKHVLGATGSTSEDAAQALYDLPDFAILDMGDFAGGVLKYLREHPIDKLTIAGGFAKLTKLAQGALDLHSSRSQVDKSFLWTLAEKAGAPESMKDQILFANTALEVLELTQSIGLDMATPIALKAKETALETLRGAPVAVEIIVTDRSGNILARV", "output": "Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A."}]}
+{"id": "function_test_3594", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNWAAAVCWALLLAATFLCDGSAAKGGRGGARGSARGGRGAARVRVRPAPRYAGSSVRAAAGAAAGAAAAAGVAAGLAAGSSWRRAAGPAELGLEDAEDGAPGSNGTGRGVYSYWAWTSGAGPTGHRHLCPLLGGALGALRLLRP", "output": "Prion-like protein that has PrP(C)-like neuroprotective activity. May act as a modulator for the biological actions of normal and abnormal PrP (By similarity)."}]}
+{"id": "function_test_3595", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTASASKTAQQLKYIKDSIKTIPDYPKAGILFRDVTSLLENPKAYSASIELLSEHYSESGVTKVVGTEARGFLFGAPVALALGVGFVPVRKPGKLPRETISESYELEYGTDTLEIHTDSIQPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVVHAAFIINLPELGGEARLTQQGIHCYSLVSFDGH", "output": "Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis."}]}
+{"id": "function_test_3596", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSSDGTPGRKRSAKVRSSVSGLEIEVLREAGDWESSTDETVRRAAEHAYAVARGDESAELCIVLGDDALVAKLNKAYRGKEGPTNVLSFPAAEMPDTGAPEAVFGGATPLLGDVVLARETIAREALDQNKKFADHLSHLTVHGVLHLLGHDHMEDVDADEMEALERDILEDLGIADPYGADHPGQ", "output": "Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA."}]}
+{"id": "function_test_3597", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQSEPMTLYGYEKITAELKDLKMVQRPNIVRDIDIARSHGDLKENSEYHAAREKQAFIENRIAEISDIVSRAKVIDPSTYEHDKVKFGSTVTIMDVETELEKTYVIVGISESDISKGYININTPLARQLLGKVEGDDVILNLPNGVSEIEIVSVEYKPINFN", "output": "Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides."}]}
+{"id": "function_test_3598", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQVILKEKVENLGVLGDIVNVKPGYARNFLIPFGKAVQATQANIKAFEAQKAELEKAEKARFEAAVAVADAIKDKVYTIAAQAGEGGKLFGSVGIAEVAEAVSNQSGKKIEKSQVRMPEGVIRSIGEFELTVHVYTDVDADIKVNVVAAEA", "output": "Binds to the 23S rRNA."}]}
+{"id": "function_test_3599", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MARKALMVKAQRPQKYTVRAYNRCKICGRSRAYMRKFGMCRICFREHALRGLIPGVTKSSW", "output": "Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site."}]}
+{"id": "function_test_3600", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLLPKRVKYRRQHRPKTTGRSKGGNYVTFGEFGLQATTTSWITSRQIESARIAMTRYMKRGGKVWIKIFPHTPYTKKPLEVRMGAGKGAVEGWIAVVKPGRILFEVAGVSEEVAREALRLASHKLPVKTKFVKREELGGETNES", "output": "Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs."}]}
+{"id": "function_test_3601", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKAGIHPNFKKATVKCACGNEFETGSVKEEVRVEICSECHPFYTGRQKFASADGRVDRFNKKYGLK", "output": "Binds the 23S rRNA."}]}
+{"id": "function_test_3602", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSITQMAAELHQALVAAGIERYAVVGHALGALVGMQLALDYPASVTVLISVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPSACSSELHAALPDSQKMVMRYGGHACNVTDPETFNALLLNGLASLLHHREAAL", "output": "Involved in pyrimidine catabolism. May facilitate the hydrolysis of carbamate, a reaction that can also occur spontaneously."}]}
+{"id": "function_test_3603", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLKFIQNNREITALLAVVLLFVLPGFLDRQYLSVQTLTMVYSSAQILILLAMGATLVMLTRNIDVSVGSITGMCAVLLGMLLNAGYSLPVACVTTLLLGLLAGFFNGVLVAWLKIPAIVATLGTLGLYRGIMLLWTGGKWIEGLPAELKQLSAPLLFGVSAIGWLTIILVAFMAWLLAKTAFGRSFYATGDNLQGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQIGFIPNQTGTGLEMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQIDSVLVLLRIPAWWNDFIAGLVLLAVLVFDGRLRCALERNLRRQKYARFMTPPPSVKPASSGKKREAA", "output": "Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane (By similarity)."}]}
+{"id": "function_test_3604", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSPTMFTIISILLSLICLVVGYFVRKTIAEAKISGARNMAEQIVEDAKRDAEALKKEALLEAKDEIHSFRVEAEQEVRERRNELQRQENRLLQKEENLDRKDESLDKRESLLEKRDHSLNERQQHIEEMESKVDDMIRLQKAELERISSLTRDEAKQIILDQVENELSHDIAVMTKESENRAKEEADKKAKNILSLALQRCAADHVAETTVSVVNLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRRETARIALDKLVQDGRIHPARIEEMVEKSRREVDDYIREMGEQTTFEVGVHGLHPDLIKILGRLKFRTSYGQNVLKHSIEVAHLAGLMASELGEDAKLAKRAGLLHDIGKAIDHEVEGSHVEIGVELATKYKEHPVVINSIASHHGDQEPTSIIAVLVAAADALSAARPGARSETLENYIRRLEKLEDISESYEGVEKSFAIQAGREVRIMVKPDSINDLEAHRLARDIRKRIEDELDYPGHIKVTVIRETRAVEYAK", "output": "Endoribonuclease that initiates mRNA decay."}]}
+{"id": "function_test_3605", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSDFAFFALEALIKCIIIIAIFASLAGLATYAERKVLAYFQRRIGPDMVGPFGLIQLVADMIKLFTKEDIIPSNSQKFIFAIAPLISAICAFVSLAAIPMLPEFTLFGRVIQPIVADINVALLFVIGTSGLCFYAVFLGGLASNNKWSILGAARGLVAIISYESVGALALIAIVMLVGSFSLVDINNYQSDGFFSWLIFKQPLAFVLFIIALFIETNRTPLCLTENDAEIVAGYGTEYSGLRWGMFFIGEYASMIAGAILVTLLFLGGFNSFWIIPGWIMMIVKSSFIFFWYFWARAAFPQLRPDQVMKMCYLILIPLAVLNLLITALAVLL", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone."}]}
+{"id": "function_test_3606", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNAIDTQNLEKHTPMMRQYLTLKAEHPEMLLFYRMGDFYELFYDDAKKASELLGISLTARGKSGGDPIPMAGLPYHAVEGYLAKLVQLRVSVAICEQVGDPATSKGPVERKVVRLVTPGTLTDEALLQEKQDNLLAAVYHGKSGYGYATLDISSGRFVVAELASTEALEAELQRTNPAELLYSEDFSEMGLISGFNGKRRRPEWEFDFDTSQKLLLDQFGTKDLRGFGLDNARLSLQAAGCLMQYVKDTQRTALPHINSIVRFNQSDSIVLDAATRRNLELTVNLQGGHENTLASVLDNTATPMGSRMLQRWIHEPLRNQQQIESRQSALTEILDTNLFETLEPQLKALGDVERITARLALRSARPRDFARLKQAISLLPEIQQSLANCQSAHLHHLARMLGEFPDELELLERAIVDNPPMLIRDGGVLKEGYNAELDQWRALSQGATDYLSELEAREKEQTGISTLKVGYNRVHGYYIEVSRRESDLVPLSYQRRQTLKNTERYIIAELKEHEEKVLSSQGKALALEKQLWEQLFDQILPKLHDLQLFAQGAAELDVINNFAERAETLNYSCPTLSQKSGIHIEGGRHPVVEQVSQTPFIANPVTLNPARKMLIVTGPNMGGKSTYMRQVALITLMTHIGCYVPAQSAVIGPVDRIFTRIGAADDLASGRSTFMVEMTETANILHNATTESLVLMDEIGRGTSTYDGLSLAWSAAEYLAQKIEAMTLFATHYFELTQLPELISNVENVHLDAIEHGDTIVFMHAVQEGAASKSYGLQVAALAGVPGKVITAAKHKLHHLESRDTNSAVDSMTTSNQQSMVFDEPVNSALNDALDKIHPDELSPRQALDILYELKRLTS", "output": "This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity."}]}
+{"id": "function_test_3607", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSEFSQTVPELVAWARKNDFSISLPTERLAFLLAIATLNGERLDGEMSEGELVDAFRHVSKGFEQTHETVAVRANNAINDMVRQRLLNRFISELADGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAQELKRAADAADEGGDDFHWHRNVFAPLKYSVAEIFDSIDLTQRIMDEQQQGVKDDIAALLNKDWRAAISSCEMLLSETSGTLRELQDTLEAAGDKLQANLLRIQDATLGGAELGFIDKLVFDLQSKLDRIISWGQQAIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQNYFDNPWTLTHANADRLLDMRDEELALRSEEVTGELPPDLEFEEFSEIREQLAAMIEQALKIYQEQQMPLNLGAVMRDYLAQYPRARHFDVARLVVDQAVRLGVAEADFSGLPAQWQAINDYGAKVQAHVIDKY", "output": "Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity."}]}
+{"id": "function_test_3608", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRIIVLGAGVIGVTSAYFLAKAGHEVTVLDRQAGPALETSYANAGEVSPGYSSPWAAPGIPMKAAKWLFMKHAPLIVRPTLDPVTWRWMLQMLANCTSARYAVNKGRMVRIAEYSRDVLMQLRADTGIRYDERMQGTLEVFRSQKQLDGIAKDIAVLKADGVPFEVLDREGCVQVEPGLKPAAHKIVGGLRLPGDETGDCFLFTNALAKLAEGLGVRFVYNVDLKRLRRDGDRIAAVETAQGDYIADSYVAALGSYMPGFLAPLGLDLPIYPVKGYSITVPILDEAKAPVSTVMDEYYKIAITRLGSRIRVGGMAEIARFNKDLPPARQATLTLSVEDLFGGAGDQKKAEFWCGLRPMTPDGTPIIGKTKFGNLFLNGGHGTLGWTMSCGSARLLSDIISGAKPEISTEGLDLSRYR", "output": "Oxidative deamination of D-amino acids."}]}
+{"id": "function_test_3609", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQIWHMEPFPCGDRRLPHHVFPPKKITTTQLGALAGVQYYKVDLEDTASMKKRLSAVKTEKNVTFTDVFTVSETMLDFDDKMEQFYEAQTQKEDVISLVVEGTCYYDVEPEDDSWIRVQLEKGDLIVIPKGLSHRFTTTPQNFVKIQRFFSRKVEGTQG", "output": "Probable inactive acireductone dioxygenase."}]}
+{"id": "function_test_3610", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MILMKDIVRDGDPVLRQVAKPLTFPLSDHYKQLAEDMMEYLVNSQDPKIAEKHQLRAGVGLAAPQVGEGVQMAALLVPDDKGEIIFKEVYVNPEIVSESVRQACLSEGEGCLSVDKVINGYVPRPDKLTIHYYTVDGEEKTIRLKDYPAIVSSHEIDHLNGHLFYDRINKKEPFALKEDTVVIS", "output": "Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions."}]}
+{"id": "function_test_3611", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNTLTIFGIAVALAMDAFAVSIAAGVFLRSIGLRHYFRLAWHFGLFQALMPIVGWYAGLSVRGLIERYDHWIAFFLLAFVSFNMIRESFDAGENHTKADPTRGLRLVLLSIATSIDALAVGLSLSVLNVSVWMPATVIGITAAVFTVGGLMMGSRAGDIPWLRRYADRVGAGVLLFIGLRILYAHGVFY", "output": "Probably functions as a manganese efflux pump."}]}
+{"id": "function_test_3612", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKIISEGETKLMVPEESTLSKKDTVFYNPMMETNRDISVSVVQSFLDNFNRDEFLMCDPLGGSGARGIRYANELKFNGDLKVSIGDINPSAVKMIKENLKLNELENVEVFHEDANVLLSKNFKIFNVVDLDPFGSPVPYLDSGIRASLTKGGLLCMTATDTAVLCGAYRKTCIRKYNAIPLKGDKELAVRLMIGYAVKMASKYDIGLKPIFSHVTDHYARTFMVTERGAGKADSAIENLGYIRQDSEQKSFKSFEEGYEKGYTGPFYLGEISDNDIVQNSLETAKNRNYSKRAVDILELISKESKIEQVGCFDIHELCSFIKKLVPPVNDIMKNLKENGFKVSRVHYNPYGLKTDAELSDLVVLISEYHSKKY", "output": "Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups."}]}
+{"id": "function_test_3613", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQWLELSVTVDTEAVESVSELFAQYGYNGGVAVEEAIIPSLDSPEYQIDTNKPVIVRTYLLANEQAADAQTQIERGLWVLGMMRPVGDLQVKTIAEEDWANAWKEHYRTRRIGQRFVIVPSWLEYEPAENDVVLNLDPGMAFGTGLHPTTQLCLELMELIEFNNTTVLDLGCGSGILAVGAAKLGSQRVLALDTDPIAVEATAENARINHAETLVTALEGSLGDAPLEHWLGWEGAQLGTPQSYRHHNEFDVILANILAKVHVVLGNDYLAALKPGGVLITSGIINEREADVVAAFDAVGLEQVERRTQGDWVAFTHRKPV", "output": "Methylates ribosomal protein L11."}]}
+{"id": "function_test_3614", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNKIRKGDQIIVLTGRDKGKQGVVSARKDDSHLLIDGINMVKKHVKPNPMKGTTGGIVEKAMPIHQSNVAIFNAATGKADRVGIKVQADGTRVRVFKSSGAEIKAA", "output": "One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.; "}]}
+{"id": "function_test_3615", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTLPDFRLIRLLPLASLVLTACTLPVHKEPGKSPDSPQWRQHQQEVRNLNQYQTRGAFAYISDDQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGNVQLVDNKGQRYTADDAEEMIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEVNYRQDGKNWKVVYGGYDSKTQPAMPANMELSDGSQRIKLKMDNWIVK", "output": "Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein."}]}
+{"id": "function_test_3616", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSNVPTELKYALSHEWVRADGDGVYSVGITEHAQELLGDMVFVDLPEVGSDVSAGSDCAVAESVKAASDIYAPISGEIVAVNTELENSPELVNSAPYTDGWLFSIKAADESELDNLLDADAYLAAIEE", "output": "The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein."}]}
+{"id": "function_test_3617", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPRQFPLNKTRNIGIMAHIDAGKTTTTERILFYTGRVHKIGEVHDGAATMDWMVQEQERGITITSAATTCQWRGHRINIIDTPGHVDFTVEVERSLRVLDGAVAVFCSVGGVEPQSETVWRQADKYGVPRIAYINKMDRIGADFFRGVSMIRERLGANPVPIQIPIGAEDQFKGIVDLITMKAIIYVDDLGKTSDVTEIPEDLADIAAEYREKLLEAVAESDEELMMKYLEGEELTEEEIRNGIRKSTLAVKMIPVLCGSSFKNKGVQPLLDAVVEFLPAPVDIPAVKGVNPDSGEEDVREVSDEEPFSTLAFKIMADPYVGKLAFFRVYSGKLSSGSYVYNSTKGKKERIGRILQMHANHREEIAEVYTGDIAAAVGLKDTTTGDTLCDEKHPIILESMQFPEPVIHVAIEPKTKADQDKMAIALQRLSEEDPTFRMSTDHETGQTIISGMGELHLEIIVDRMMREFKVEANVGRPQVAYKETIRSKAKAEGKFVRQSGGRGQYGHAVIEIEPLEPGAGYEFVNKIVGGVIPREYIPAIDNGIREAAETGVLAGYPTVDFRVTLVFGSYHDVDSSEMAFKIAGSMAFKEGAAKANPVILEPVMKVEVTVPEEYMGDVIGDINSRRGRIEGMESRGSTQVVRGYVPLSEMFGYATDLRSRTQGRGQYVMMYSHNEEVPRNIAEGIIAKRKG", "output": "Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome."}]}
+{"id": "function_test_3618", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAKKNAKNSKNSSASIARNKRATFDYKFEEKLEAGLSLMGWEVKSIRMGKVNLSESYVFLREGEAYLFGCTIAPLNTASSHVVCDPLRSRKLLLKRKELDKLQGLVDRKGYSIVPISMYWQKGAWVKIEIGLGKGKKEHDKRDDTKDREWQIEKARTIKKAVQQ", "output": "Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation."}]}
+{"id": "function_test_3619", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNRIQQTFQTSSAPFWYAQLELGFCYENSRTIMSHRKHYGPVRVQKMLWPEKTGVCHAIIVHPPAGIAGGDHLTFQIETERQAHAVITTPGAGKWYRTNGKQAFQHIYLNVKDDSILEWMPQETMLFDGALAHSETDIHLEQTASFIGWDMLVLGRQARAENFVQGGYHNQFKLWRKNKLLVADTLYFEGGDRWLSSCLGMNNQAVMASFWAVPPEKFRSSFYLEQHIELIRELIMRMDVPVTLTLLEDVLCARFLGNDVRRCHDAFAAIRAKLRRYWFDLDEEFPRIWKT", "output": "Required for maturation of urease via the functional incorporation of the urease nickel metallocenter."}]}
+{"id": "function_test_3620", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MVEALLSGIVPGLIPITLAGSFVIAYLQYRRGDQLDL", "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetG is required for either the stability or assembly of the cytochrome b6-f complex."}]}
+{"id": "function_test_3621", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDVISCSSNTLKGLYDISGVEVGQHLYWQIGGLQVHAQVLITSWVVIAILLGSAIIAVRNPQTIPTAGQNFFEYVLEFIRDVSKTQIGEEYGPWVPFIGTMFLFIFVSNWSGALLPWKIIQLPHGELAAPTNDINTTVALALLTSVAYFYAGLTKKGLGYFSKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPLVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH", "output": "Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane."}]}
+{"id": "function_test_3622", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTKHTLEQLAADLRRAAEQGEAIAPLRDLIGIDNAEAAYAIQHINVQHDVAQGRRVVGRKVGLTHPKVQQQLGVDQPDFGTLFADMCYGDNETIPFSRVLQPRIEAEIALVLNRDLPATDITFDELYNAIEWVLPALEVVGSRIRDWSIQFVDTVADNASCGVYVIGGPAQRPAGLDLKNCAMKMTRNNEEVSSGRGSECLGHPLNAAVWLARKMASLGEPLRAGDIILTGALGPMVAVNAGDRFEAHIEGIGSVAATFSSAAPKGSLS", "output": "Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid."}]}
+{"id": "function_test_3623", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNALTAVQNNAVDSGQDYSGFTLIPSAQSPRLLELTFTEQTTKQFLEQVAEWPVQALEYKSFLRFRVGKILDDLCANQLQPLLLKTLLNRAEGALLINAVGVDDVKQADEMVKLATAVAHLIGRSNFDAMSGQYYARFVVKNVDNSDSYLRQPHRVMELHNDGTYVEEITDYVLMMKIDEQNMQGGNSLLLHLDDWEHLDHYFRHPLARRPMRFAAPPSKNVSKDVFHPVFDVDQQGRPVMRYIDQFVQPKDFEEGVWLSELSDAIETSKGILSVPVPVGKFLLINNLFWLHGRDRFTPHPDLRRELMRQRGYFAYATNHYQTHQ", "output": "Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG). Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate."}]}
+{"id": "function_test_3624", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGIMHTSELLKHIYDINLSYLLLAQRLIVQDKASAMFRLGINEEMATTLAALTLPQMVKLAETNQLVCHFRFDSHQTITQLTQDSRVDDLQQIHTGIMLSTRLLNDVNQPEEALRKKRA", "output": "Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways."}]}
+{"id": "function_test_3625", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MALTLEELVKRFGGEIAGDAQCKVSGLAPLDQAGPQQLAFLANPKYLSQVETTRAGAVLIAPKDLEKLRAATDGQPAGPRMAGPLNFIVTPNPYAYFARVAQMFIDLATPPRAPGVHPSATIDPAAQVAASAVIGPHVTVEAGAVIEDGVQLDANVFIGRGTTIGAGSHLYPNASVYHGCKIGPRAIIHAGAVIGSDGFGFAPDFVGDGDARTGSWVKIPQVGGVTVGPDVEIGANTTIDRGAMADTVIDECVKIDNQVQIGHNCRIGAYTVIAGSAGIAGSTTIGRHCMIGGAAGIAGHVTLGDYVIITAKSGVSKSLPKAGIYTSAFPAVDHGEWNRSAALVRNLDKLRERIKALETALAAQGGTDA", "output": "Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell."}]}
+{"id": "function_test_3626", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLRFTDEHEWLRLDGDVATVGITAHAAEQLGDLVFVELPKVGVKLTKGEAAAVVESVKAASDVYAPLSGEVTEVNEAALSDPASVGADPQGAGWLYRLKLDDVSAMDALMDEAAYADFAK", "output": "The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein."}]}
+{"id": "function_test_3627", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIAEAKITSAEEAADKIIEDAKKQGESMKREALLEAKEEIHTQRNELEKETRERRNEIQRFERKLEQKEESLSKQQKQLEQKEKEIAQKDEKITNKEQELEKIYQQQVEELENLSGLTTQEAKDMLLNRVREDISHETAMMIKEMESRAKEEADKKAREIITTAIQRCAVDHVAESTVSVVSLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARLALEKLVSDGRIHPARIEEMVEKAQKEVDEQIREEGEQATLDTGVHGLHSELIKLLGRLKFRTSYGQNVLNHSIEVARLCGVMAHELGTDVNTAKRAGLLHDIGKAVDHEYEGPHVTIGAELGKKYGESSNVLHAIATHHGDEEPETIEAVLVQAADAISAARPGARRETLESYIKRLEKLEEIADSYKSVEKAYAIQAGREVRIMVKPEQADDETSINLARDISKQIEAELDYPGQIKITVIRETRAVEYAK", "output": "Endoribonuclease that initiates mRNA decay."}]}
+{"id": "function_test_3628", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSDNTEKKTLRTVEGRVVSNKMDKTVTVLVERQVKHALYGKYIKRSTKLHAHDADNACKEGDVVRVTEIAPMSKTKNWRVVEVITRAAE", "output": "One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA."}]}
+{"id": "function_test_3629", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPIIKSAIERVRTSEKAEARNASQLSQMRTAIKKFDKAKLAGADNLDDLYKAAISAIDRAHSKGLIKANKAARDKSRLSARYAK", "output": "Binds directly to 16S ribosomal RNA."}]}
+{"id": "function_test_3630", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIVTEILGNIHEDSGRELVAGRHVEKVVLPSAELVKRIQRLRTDHDRQIGLRLPAGAPDLRDGDVVAVEDAAPSGAGHGDGEQDGTGAPGRGNAVVIQVLPTDVLVIGARSVVEMAFVAHSLGNRHLQAQFFDADSEYGAEVMVVQYDHTVQDFLDHHGVPYSRQERVMPVPFRHAEHTH", "output": "Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly."}]}
+{"id": "function_test_3631", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDDVNSIVLAAGQAAEEGGTNNFLVPNGTFFFVLAIFLVVLAVIGTFVVPPILKVLRERDAMVAKTLADNKKSAEQFAAAQADYEKAMAEARVQASSYRDNARAEGRKVVEDARAHAEQEVASTLQQANEQLKRERDAVELDLRANVGAMSATLANRIVGVDVTTPAAAG", "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "}]}
+{"id": "function_test_3632", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MARIAGVNIPTNKRVIIALQYIHGIGPKKAEEICEKVSIPPERRVVDLTDAEVLQIRETIDRDYIVEGDLRREVAINIKRLMDLGCYRGLRHRRQLPVRGQRTHTNARTRKGKAKPIAGKKK", "output": "Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites."}]}
+{"id": "function_test_3633", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKRLLVACCFLSGLISASALADASTDLQNRLSKVNSFHASFSQAVTSSDGAVVQEGEGELWVKRPNLFNWHMTSPDESVLISDGETLWFYNPFVEQATATWLKNATGNTPFMLITRNNPDDWKQYNVKQKGDDFELTPKSASGNLKQFAISVTPSGTIKSFTAVEQDGQRSAYTLKSQQSSVVDASKFTFTPPKGVTLDDQR", "output": "Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)."}]}
+{"id": "function_test_3634", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNKIRKGDRVIVRTGKDKGKQGTVLAVLAEHVTVEGVNVAKKHVRPNPMLGTTGGVVDKIMPIHISNVALVDANGKPSRVGIKVEGGVKTRVLKTTGAAVGA", "output": "One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.; "}]}
+{"id": "function_test_3635", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MARYRGAVERLERRFGVSLALKGERRLSGKSALDKRAYGPGQHGQRRAKTSDYGLQLKEKQKAKMMYGISEKQFRSIFVEANRLDGNTGENLIRLIERRLDNVVYRMGFATTRSSARQLVTHGHVLVDGKRLDIPSYFVRSGQKIEIKEKTKSNPQVVRAMELTAQTGIVPWIDVEKDKKYGIFTRYPEREEVVVPIEERLIVELYSK", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; "}]}
+{"id": "function_test_3636", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSAKGVSEKEHSPMMRQYLDVKDRYPDYLLLFRVGDFYETFFDDAREVAAALNIVLTRRSNEIPMAGFPHHASEGYIAKLVKKGYKVAVCDQVEDPAVAKGIVRREITDIITPGVTYSDSILDDRHNNYLCAIVFLRVGRQTVCGAAFIDVTTGEFRIAGLLPEDASVFLRSLHPAELLVSAADRERSETLRHALPAGTAFTVLDEWLFREEQAGEILARQFRTHSLKGFGIHDNPAGQVAAGVILHYLEETRQSSLQYITRITPLQSGDYMTLDLQTKRNLEIISSMQDGSINGSLLQVIDRTRNPMGARLLRQWLQRPLLRAADITMRLDAVDELKKMKPFRESVCCDLGQISDLERALARIATLRAIPREVRQLGSALAVIPLLKQSFQDTVSKRLCSIADALMPLPDLVAMIESAVDPEAGASMRDGGYIRKGYHQELDDLRQTASTAKERLLEIQQEERERTAIGSLKVQFNRVFGYYIEISKANRDKVPPYYEKKQTLVNAERFTIPALKEYEEKILNAEERSLVLEQQLFQALCCRIAGHAEVIQENAALIAEIDCLAAYAVCADEYGYCKPLIAEHTGLRILNGRHPVLERILPADEPYIANDALFDDRQKMLMITGPNMAGKSSYLRQTGLIVLLAQAGCFVPAEQAEIGVVDRIFTRVGASDNLASGESTFLVEMNEAADILNNATAKSLLLLDEIGRGTSTYDGLAIAWSMCEYIHRQIGARTLFATHYHELAELEGLLPGVVNYNASVLESGDRVIFLRKIVRGASDNSYGIEVARMSGMPSAVITRAKAILAGMEKRDIATPSSSGLSLQSMQISLFDEIDTRLRTAIEVIDIDRMTPLDALVELKKLQGLVRTGNII", "output": "This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity."}]}
+{"id": "function_test_3637", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MATYIVGDLHGCFDELQLLLKQVNYNPAQDELWLTGDLVARGAKSLECLRFVKDPKNNAKTILGNHDLHLLATLLGVKKVKPNDQVDAIFAAEDRADLQNWLRNQPLLIQHPKYGFLLTHAGISPEWNLTETIACAREAEAVLQSGHYADYIAQMYENTPDHWSAEWQGIERWRYIINVFTRMRFCYADKRLDFACKLPVEDAPNELKPWFKLDNPLFHQQDIIFGHWASLMGKADKPNIYALDTGCAWGNHLTMIRWEDKQIFTQERLK", "output": "Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP."}]}
+{"id": "function_test_3638", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLITFEGIDGAGKSTQVVKLKRHLQERGREVLTLREPGGTPVAEQIRELLLESHNDITSIAELLLFSASRAELMEKIIVPALEDGCDVILDRFFDSTTAYQGYGRGLNLDMLAEINRIASHGIRPDITFYLDLTPEDALLRKFSEKSLPLAFESEELDRMENSGLEFYQRVRAGYHAILEAEPQRIIMIDALLTPQEIHRKILSALQALEVPEDGKR", "output": "Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis."}]}
+{"id": "function_test_3639", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQQQKIRIRLKAFDYRLIDQSAAEIVDTAKRTGAIVRGPVPLPTRIQRFDILRSPHVNKTSRDQLEIRTHQRLMDIVDPTDKTVDALMKLDLPAGVDVEIKLQ", "output": "Involved in the binding of tRNA to the ribosomes."}]}
+{"id": "function_test_3640", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSEKLIVKCPTCRTEVIWDESSPYRPFCCKRCQLIDLGEWAAEEKRIPSQSESNDSDEWSEMPEQDPKPFN", "output": "Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase."}]}
+{"id": "function_test_3641", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSVVSTTPASQDACYISLLGLAEYFRTSQPPNIKKCIQCLQALFTFQPPSKVEARTHLQMGQVLMAYTCNIDLARRHLEQAWSIAEPLMNFDDVKFDTASLLAQLHLKTEQSSHAKAMLRRAVELSQNNVYWHCKLLLQLSQIHASDREYSLASDLLAVGAESAEEAGATYLKVLFLLSRAMILMIERKTNDVLALLNSAGQIIDNNIPNPHQKEYLKVFFLVLQVCYYLALGQVKTVKPSLKQLQMSIQTIMAPNWPSDETIFGGNQLEMFVWLPKEQLYVLVYLVTVSHSMMAGYMDKAQKYTEKALTQIEKLKQQEDKSILSVFKVILLEHIVMCRMVMGNRELAIREIAAARDVCLAVPHRNLLKRHSAQLHCLIGLYSMSTSFFEHAERQFLVCVNETTERDLKLFANLNLAIIYLRTKREADLKQILDAVSTENTHTYSSQALMGGFYYVQGLHAFHKNSFHEAKRFLRETLKMANAEDLNRLTSCSLVLLSHVFLSIGNSKESMNMVTPAMQLASKIPDIHVQLWGSAILKDLHRMSKDAQHEKEAYANHVKYSENLIADQRKCVQSAHHELINWFQGNPPVTSNSSLNPAVTVPTTETSTSALQQPQQPAAQFGQFY", "output": "Required for association of the cohesin complex with chromatin during interphase. Plays a role in sister chromatid cohesion and normal progression through prometaphase (By similarity)."}]}
+{"id": "function_test_3642", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKVILLERLEGWGGLGDVVDVKDGYARNFLLPRQKALRANGANLKVFEAQRAEIEARNAKAKEAAGKAGEKLDGTQYVLIRQAGESGQLYGSVSGRDVADAVNAEGGKVERSMVVLDKPIKTLGMHEVKIRLHSEVAVTVTLNIARSQDEADRQARGENVIASQFEDERMAAEQAAADLLEGGAGQQASEYTEAQA", "output": "Binds to the 23S rRNA."}]}
+{"id": "function_test_3643", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLATTFVMTLASICAWLIDTWILIPLDLIYLRTLAFILVIAVVVQFTEMVVRKTSPALYRLLGIFLPLITTNCAVLGVALLNINLGHHFLQSALYGFSAAVGFSLVMVLFAAIRERLAVADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL", "output": "Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR."}]}
+{"id": "function_test_3644", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSTGLLAKKVGMTQIFTPEGDCVPVTVLEAGPCTVVRRKTAEKDGYDAVVIGFGVVDEKHAHRLSKPEVGVFKKAGTPIFRHVKEIRVKDAKQLGDLKAGDVLTVDKVFKANQRIDVAGVTKGRGFTGVMKRWNMKGAARDSSTAHEHHRHVGAIGQRKTPGKVWKGKHLPGHYGVDNVTIQNLTVVGIEAEQNVLLVSGAVPGHADGLLFVNTAAKGQPRIKQKQEVRERAKPKV", "output": "One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit."}]}
+{"id": "function_test_3645", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRPYAETMRKVIGHLANGNLEYKHPYLEERDVKRVGYLVVSTDRGLCGGLNINLFKKLLADMKAWSDKGVQCELAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAYDEGRLDKLYIVSNKFINTMSQVPTITQLLPLPASEDDDLKRTAWDYLYEPDPKALLDTLLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQELTEIVSGAAAV", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex."}]}
+{"id": "function_test_3646", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQIGKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLGQLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIPNYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYRQDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHDLRVDTQGVRVEAK", "output": "Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate."}]}
+{"id": "function_test_3647", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTDVTLKALAAERQVSVDRLVQQFADAGIRKSADDSVSAQEKQTLLAHLNREAVSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERLAAEEQAQREAEEQARREAEEQAKREAQQKAEREAAEQAKREAAEKAKREAAEKDKVSNQQTDDMTKTAQAEKARRENEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTATPEPVEDTSDYHVTTSQHARQAEDENDREVEGGRGRGRNAKAARPAKKGKHAESKADREEARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAPVVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETDNGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAGVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSIPVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASNAILVGFNVRADASARKVIESESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLAEVRDVFKSPKFGAIAGCMVTEGTIKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRVGDMIEVFEIIEIQRTIA", "output": "One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex."}]}
+{"id": "function_test_3648", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLFSPPLQRATLIQRYKRFLADVITPDGTTLTLHCPNTGAMTGCATPGDTVWYSTSENTKRKYPHTWELTETQFGAFICVNTLRANQLTKEAIQENRLPALEGYNILKSEVKYGAERSRIDFMLQADFRPDCYIEVKSVTLAEKENGYFPDAITERGQKHLRELMGVAAAGHRAVVVFAVLHSAITRFSPARHIDIKYAQLLSEAQNKGVEVLAYKAELSAQKMELNEPVPITL", "output": "Binds to DNA non-specifically. Could be a regulatory factor involved in maltose metabolism."}]}
+{"id": "function_test_3649", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSKQDEVIVVGKFGASYGIRGWLKVVSFTDQPESIFDYKPWLIQVKGEWVEFSVESWKRHKGLVCKLKGLDVREEAQTYTNLEIAVKADVLPELSEDEFYWRELFGMEVVTTKGYALGVVDDIFETGSNDVLVVKANLKDAFGKKERLIPFIDEQVIKLIDREAQRIEVDWDPGF", "output": "An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes."}]}
+{"id": "function_test_3650", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSHWITNRQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKVMFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE", "output": "Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs."}]}
+{"id": "function_test_3651", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDSLITSLEERKQALFALPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTVNSFADIENHIFEAENLNDTFNFIRAKHEINSVESQLNLVEEDIASIREALNILKEQEEKNSARVTHALDLYEKLQASISENEDNFGSTMPEIDKQMKNIETEFSQFVALNSSGDPVEASEVLDRAEEHTIALGQITEQIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELVTLDLDRAREENTHIQERIDSLYEVFEREIAAYKVAAKNSKMLPRYLAHVKRNNEQLKDEIARLSRKYILSETESLTVKAFEKDIKEIEDSTLAVAEQFGLQEKPFSELQVTFERSIKTLTNVESGQMDVFAAVKDIEKIESQARHNLDVYVTQLHMIKRYMEKRHLPGIPQDFLSAFFTTSSQLEALMDELSRGRINIEAVSRLSEVATVAIANLEDLTYQVVQNATLTEQLLQYSNRYRSFEAGVQSSFEHALRLFEVENDYQASFDEISYALETVEPGVTDRFVNSYEKTREHIRF", "output": "Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization."}]}
+{"id": "function_test_3652", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTTMAETQTWQTVLGEEKQEPYFQEILDFVKKERKAGKIIYPPQKDIFNALKLTPYEAVKVVILGQDPYHGPNQAHGLAFSVRPGVPAPPSLQNIFKELHADLGVSIPSHGFLEKWAKQGVLLLNAALTVEAGKPQSHANIGWHRFTDKVIESLNDHPEGIVFLLWGSYAQKKSQLITNLRHRILKAPHPSPLSAARGFLGCRHFSKANQLLHEMGRGEIDWALDEKVS", "output": "Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine."}]}
+{"id": "function_test_3653", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNKPASIGLLQQPKPFFMIFFVELWERFGYYGVQGILAVYFVHKLGFSQEQAFTTFGAFAALVYGLIAIGGYVGDHLLGTKRTIVLGAIVLTVGYFMTGLSILKPELIFYALGTIAVGNGLFKANPASLLSKCYPPKDPRLDGAFTLFYMSINIGSLFSLAIAPVIAEKFGYAVTYNICGIGLIIALLVYVLYRNTVRNIGSEPDHRPINYKNLLLVLAGTVTMVFVCAWLMHNVKIANIVLIGLSVVIVFIFFREAFKQDKVGRNKMFVAFILMLQAIVFFILYAQMPTSLNFFAINNVHHQLLGFNINPVSFQALNPFWIVVASPILAALYTHWGSRSKDLTMPAKFTVGMFLCSLGFLTAAAAGLWFADEQGLTSPWFIVLVYLFQSLGELMISALGLAMVAALVPQYLMGFILGMWYLTQATSFLLGGYVAAFTAIPEGITDPLETLPVYTNVFGKIGITTFIVAIIMAITVPLLNRMMNGKQKA", "output": "Proton-dependent permease that transports di- and tripeptides."}]}
+{"id": "function_test_3654", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAQTTNDIKNGSVLNLDGQLWTVMKFQHVKPGKGPAFVRTTIKNVLSGKIVDKTFNAGMKMEFETVDNRTLQYSYEDGDNFVFMDMTTYDQIMVPKTLLGDKAKFLLEGTDCLVSFHDGTPLSVDLPGSVVLTITHTEPGLQGNRSNAGTKPATVETGAEIQVPLFINEGDRVKINTEDGSYTGRENN", "output": "Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase."}]}
+{"id": "function_test_3655", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAIGLVGRKCGMTRIFTDAGVSVPVTVIEVDPNRITQIKTLETDGYQAVQVTTGERRESRVTNAQKGHFAKAGVAAGRLVKEFRVTEAELEGREVGGTIGVDLFTVGQIVDVTGQSKGKGFQGGVKRWNFRTQDATHGNSVSHRVLGSTGQNQTPGRVFKGKKMAGHLGDERVTVQGLEIVSVDTERSVLVVKGAIPGATGGDVIVRPTIKA", "output": "One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit."}]}
+{"id": "function_test_3656", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIDFELKQKIDEAKKKFEDIIKVFHPENKRKELEELEKQMGDSDFWSDQRKAREISQKAQRIRKIIDDMKDIEAKFEDLDAAIELSDEDQSFVETIKEMVEEIEKKVKTFELELILNGKFDASNAYLTIHPGAGGTESQDWASMLLRMYMRWAERKGFDVQIVDYQPGEEAGIKSAMIYIKGDYAYGYLKYERGVHRLVRISPFDANKRRHTSFASVNVIPEIDDDIDIEINPEDLRIDTYRASGAGGQYVNKTESAVRITHIPTGIVVTCQTERSQLQNKETALKVLKARLYQLELEKRQKQLEEIQGELKDISWGNQIRSYVFQPYTMVKDHRTNVETGNIDAVMDGEIDIFIESELIHFAGIRNKQ", "output": "Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA."}]}
+{"id": "function_test_3657", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSKSDLNLLVENIKFEHLNVFYDFVVSVLNALSISDFELSVILCDNAYIQELNNKFRNKNEPTDVLSFNYNEHNELNEDLVDGINYKIQGDLVISFEYLKFSAQEFNVEIYEELQRVTIHGILHLMGYKHETNDFQKEGMLILQENILKENKRVF", "output": "Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA."}]}
+{"id": "function_test_3658", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MHCPFCAYADTRVVDSRLADDGGSVRRRRECPQCGQRFTTFERAELALPVVVKTDGRRESFNEEKLQRGLTRALSKRPVATARVDAAVRMIQRRIRERGEREIPARLIGELVMEALRDLDPVAYVRFASVYRRFEDVDAFSVEIARMKEAEVPDGGDDLNRGD", "output": "Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes."}]}
+{"id": "function_test_3659", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSIQVFCDFDGTITNNDNIMSIMEKFAPPEAEEVKNRILSQELSIQEGVSQLFQLIPTNLHDEIIQFLIETAEIRNGFHEFIQFVNENNISFYVISGGMDFFVYPLLQGLIPKEQIYCNETDFSNEYITVNWPHPCDRLCQNHCGLCKSSLIRKLSDTNDFHIVIGDSITDLQAAKQADKVFARDFLITKCEENHISYTPFETFHDVKTELKHLLEVKL", "output": "Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene)."}]}
+{"id": "function_test_3660", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAIQHPDIQPAVNHSVQVAIAGAGPVGLMMANYLGQMGIDVLVVEKLDKLIDYPRAIGIDDEALRTMQSVGLVDNVLPHTTPWHAMRFLTPKGRCFADIQPMTDEFGWPRRNAFIQPQVDAVMLEGLSRFPNVRCLFSRELEAFSQQDDEVTVHLKTAEGQREIVKAQWLVACDGGASFVRRTLNVPFEGKTAPNQWIVVDIANDPLSTPHIYLCCDPVRPYVSAALPHAVRRFEFMVMPGETEEQLREPQNMRKLLSKVLPNPDNVELIRQRVYTHNARLAQRFRIDRVLLAGDAAHIMPVWQGQGYNSGMRDAFNLAWKLALVIQGKARDALLDTYQQERRDHAKAMIDLSVTAGNVLAPPKRWQGTLRDGVSWLLNYLPPVKRYFLEMRFKPMPQYYGGALVREGEAKHSPVGKMFIQPKVTLENGDVTLLDNAIGANFAVIGWGCNPLWGMSDEQIQQWRALGTRFIQVVPEVQIHTAQDNHDGVLRVGDTQGRLRSWFAQHNASLVVMRPDRFVAATAIPQTLGKTLNKLASVMTLTRPDADVSVEKVA", "output": "Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI)."}]}
+{"id": "function_test_3661", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQNDQQRLIDQVEGALYEVKPDASIPDDDTELLRNYVKKLLKHPRQ", "output": "Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS especially during phosphate starvation, but also in stationary phase and during nitrogen starvation. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway."}]}
+{"id": "function_test_3662", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKPENKLPVLDLISAEMKTVVNTLQPDLPPWPATGTIAEQRQYYTLERRFWNAGAPEMATRAYMVPTKYGQVETRLFCPQPDSPATLFYLHGGGFILGNLDTHDRIMRLLASYSQCTVIGIDYTLSPEARFPQAIEEIVAACCYFHQQAEDYQINMSRIGFAGDSAGAMLALASALWLRDKQIDCGKVAGVLLWYGLYGLRDSVTRRLLGGVWDGLTQQDLQMYEEAYLSNDADRESPYYCLFNNDLTREVPPCFIAGAEFDPLLDDSRLLYQTLAAHQQPCEFKLYPGTLHAFLHYSRMMKTADEALRDGAQFFTAQL", "output": "Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity."}]}
+{"id": "function_test_3663", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MALLPDKEKLLRNFLRCANWEEKYLYIIELGQRLPELRDEDRSPQNSIQGCQSQVWIVMRQNAQGIIELQGDSDAAIVKGLIAVVFILYDQMTPQDIVNFDVRPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAAALS", "output": "Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process."}]}
+{"id": "function_test_3664", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRRANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFMADPLYLFRVWDGGMSFHGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNFPFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYIRKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVIMMVWAYRRSPQQHVS", "output": "Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins."}]}
+{"id": "function_test_3665", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRYLATLLLSLAVLITAGCGWHLRDTTQVPSTMKVMILDSGDPNGPLSRAVRNQLRLNGVELLDKETTRKDVPSLRLGKVSIAKDTASVFRNGQTAEYQMIMTVNATVLIPGRDIYPISAKVFRSFFDNPQMALAKDNEQDMIVKEMYDRAAEQLIRKLPSIRAADIRSDEEQTSTTTDTPATPARVSTTLGN", "output": "Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane."}]}
+{"id": "function_test_3666", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSDHKTLIKNGMWANNPALVQLLGLCPLLAVSSTVTNALGLGIATLLVLVGSNVSVSLVRNHVPKEVRIPVFVMIIASLVTCVQLLMNAYAYGLYLSLGIFIPLIVTNCIIIGRAEAFASKNEVLPAAQDGFWMGLGMTSVLVVLGAMREIIGNGTLFDGADLLLGDWASVLRIQIFQFDNSFLLALLPPGAFIGVGFLIALKNIIDNQAKSRQPKQEKPVIERARVTNA", "output": "Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane."}]}
+{"id": "function_test_3667", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSDVAEKVKKIIVDQLGVSADEVKPEASFVEDLGADSLDLTELIMAMEEEFEVEIADEDAQKILKVQDAIAYIEEKK", "output": "Carrier of the growing fatty acid chain in fatty acid biosynthesis."}]}
+{"id": "function_test_3668", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAFNFNWSPLMADAGFYTRAQDLLTAALNKSPKPPIIVDDIKVTELNLGSIPPDLEILEVGDLAEDRFRGIFKMSYNGDAFLTLKTRVQANPLNTFLVTRPSFASPKPLAAAAGLTIPLQITLSEFRLSGFVVLVFSKQKGITVVFRNDPLESLKVSSTFDSISFVRDYLQKAIEGQLRALFMDELPAIIHRLSLRLWVPEYRDRESESVNTLDQSSGPGQDPLASPPQDPVDASGNALNPSEVASLSLDSGVEIHSLFSQKNLLRLAALTDSQRTLSLFTPSIKDVVYRAWTASTELGDSNTLTSPASPVLSRAQSHIGSLHSFVDNASTISMQSGGSSNFSGHGLNLRSGRHPRPHGKKRKKRVVDLRRPKTTDDMESVSGESVFSSENATSAPTIFSSPAQFSEEKNDDPVTPPLAPQNDLHLPTIHERRRISQGEHTLTRRSVPSMSEVAQPSSSRNSAAMIADTWPDPDATPRNSIRLPSSDRANNPLTTAHLPSSAIQYPPPIPDNNDPRQQAWLSKMAAELARRIQEEKVGPSGSRPFPDFWDDHSREEIPPPAYGH", "output": "Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm34 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10."}]}
+{"id": "function_test_3669", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQLSDFDFDLPERLIATRPARPRTAARLLLAEGDRIEDRHVRDLVGIFRPGDRLVLNNTRVIPARLTGTRTRGEAEARIEVTLMEPAAAGGWRAMAKPLRKLKPGETIRFSDALSAEVAEKGETDLRLVFDRAGAAFDAALADAGAMPLPPYIAARRAPDAQDDEDYQTVFARHAGAVAAPTASLHFDRPLLEALAARGVGFTEVTLHVGAGTFLPVKVEDVTTHRMHAEWGEVTEAAAAEIAATKAAGGRVIPVGTTALRLIESAAASGAIRPWRGETDIFIYPGYRFRVTDALMTNFHLPKSTLLMLVSALMGQERIRAIYDHAVRHDYRFFSYGDASLLIPGG", "output": "Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)."}]}
+{"id": "function_test_3670", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MHVKTGDEVLVIAGKDKGRRGKIKRALPAVNRVVVEGINIVKRHQKPRGPGRPGGIIEMEAPLHASNVMLICPSCGRASRTGKRFLEETDHKGRPRKVRYCKACDAVIDK", "output": "One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.; "}]}
+{"id": "function_test_3671", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSALETQALGMIPMVIEQSGRGERSYDIYSRLLKERVIFLVGEVNDQTANLVVAQLLFLESENPDKDISFYINSPGGSVTAGMAIYDTMQFIKPDVSTLCCGFAASMGAFLLAAGAKGKRYSLPNSKIMIHQVLGGARGQATDIEIHARDILRTKDQMNRILAERTGQPIEKVKADTERDYFMTADEAKDYGIVDQVIAKRP", "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins."}]}
+{"id": "function_test_3672", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "VDPAQVSGSWRTAAIASD", "output": "Binds the chemical odorant, 2-isobutyl-3-methoxypyrazine."}]}
+{"id": "function_test_3673", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "IIGDTINGAITTADNIAGKIGII", "output": "May act as an antimicrobial peptide."}]}
+{"id": "function_test_3674", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNACIINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIFPVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLNFQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITRSVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY", "output": "DNA-binding global transcriptional regulator which is involved in the adaptive response to starvation and acts by directly or indirectly controlling the expression of numerous genes in response to nutrient availability. During rapid exponential growth, CodY is highly active and represses genes whose products allow adaptation to nutrient depletion."}]}
+{"id": "function_test_3675", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAKIIGIDLGTTNSCVSVMEGGEPVVIPNAEGSRTTPSVVSFQANGERLIGQVAKRQAITNPEKTIISIKRYMGTDHKVNIDNTEYTPQQISAMVLQKLKADAEAYLGEKVTQAVITVPAYFNDSQRQATKDAGKIAGLEVLRIINEPTAASLAYGLDKMDTNEKILVYDLGGGTFDVSILELGDGVFEVKATNGDTKLGGDDFDQKLIDYIAETFKAENGIDLRNDKMAIQRLKEAAEKAKIELSSATQTNINLPFITADATGPKHIDMNLTRAKFNELTHDLVQRTLEPIKKSLEGSGYAMSDIDKIIMVGGSTRIPAVQDAVKDFTGKELSKGVNPDEVVAMGAAIQAGVLTGEVKDVLLLDVTPLTLGIETFGGVSTTLIEKNTTIPTRKSQVFSTAADGQTSVEIHVVQGERSMAADNKTLGRFTLSGIAPAPRGIPQIEVTFDIDANGIVNVSAKDKGTGKEANITITASTNLTDDEIEKAVNEAKKFEAEDKKRKESIEVKNNADQIVYQTEKTLTDLGDKVSAEDKAQIEEKVKVVKDVKDGEDLEAIKKATEDLTQTFYGISSKIYQQANPEGAPGAGFDPNNMGGANAGNASAGNDKKDDNVVDADFKVEDDK", "output": "Acts as a chaperone."}]}
+{"id": "function_test_3676", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MVDHARAARMAKRIQTIVASAIERQIKDRRLELVTITDARVTGDLHDATVFYTVRGTDIGTEPDYDQAAEALTRAKGQLRKIVGDELSVRFTPTLSFELDTVPEASAHMEELLARARARDAELAKLKEGAQPAGDANPYKTSDEEED", "output": "One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA."}]}
+{"id": "function_test_3677", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MARLAGVDLPRNKRMEVALTYIYGIGPTSAKQLLEKTEISPDLRTDALTDDQVAKLRDAIEAEYTVEGDLRRQVQADIRRKIEIGSYQGLRHRRGLPVRGQRTKTNARTRKGPKKTIAGKKK", "output": "Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites."}]}
+{"id": "function_test_3678", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKSDKTPKINKFIRRLYKIVNDNSFSEIQWTTDGLRFYITDKTAFMLNGLKYLSKTTEYSAFVRLLYVYGFSKSKSLNAYEEEYYHKNFKRDGDNLLPCIQRTVETKTTLLQKNTNRTPNQLQDLLQYLNNQNFKLEGEIKSLKDRVDQQDCTINGLVQLLTRIFRTNDSNKDMLLPLNITEHGSPINNELRINYDKNQVARLMADTPNIDGRLENTNIELSNNKNFLFDSDDEDSIYKTNFF", "output": "DNA-binding transcription factor that specifically binds heat shock promoter elements (HSE) and activates transcription."}]}
+{"id": "function_test_3679", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKVWMAILIGILCWQSSVWAVCPAWSPARAQEEISRLQQQIKQWDDDYWKEGKSEVEDGVYDQLSARLTQWQRCFGSEPRDVMMPPLNGAVMHPVAHTGVRKMVDKNALSLWMRERSDLWVQPKVDGVAVTLVYRDGKLNKAISRGNGLKGEDWTQKVSLISAVPQTVSGPLANSTLQGEIFLQREGHIQQQMGGINARAKVAGLMMRQDDSDTLNSLGVFVWAWPDGPQLMSDRLKELATAGFTLTQTYTRAVKNADEVARVRNEWWKAELPFVTDGVVVRAAKEPESRHWLPGQAEWLVAWKYQPVAQVAEVKAIQFAVGKSGKISVVASLAPVMLDDKKVQRVNIGSVRRWQEWDIAPGDQILVSLAGQGIPRIDDVVWRGAERTKPTPPENRFNSLTCYFASDVCQEQFISRLVWLGAKQVLGLDGIGEAGWRALHQTHRFEHIFSWLLLTPEQLQNTPGIAKSKSAQLWHQFNLARKQPFTRWVMAMGIPLTRAALNASDERSWSQLLFSTEQFWQQLPGTGSGRARQVIEWKENAQIKKLGSWLAAQQITGFEP", "output": "Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction."}]}
+{"id": "function_test_3680", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MARYLGPKLKLSRREGTDLFLKSGVRAIDSKCKIEQAPGQHGARKPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVVYRMGFGATRAEARQLVSHKAIVVNGRVVNIASYQVSPNDVVSVREKAKKQSRVKAALELAEQREKPTWLEVDAAKMEGVFKRQPERSDLSADINEHLIVELYSK", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; "}]}
+{"id": "function_test_3681", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MWINRLVKHPSYSVLRFYTKRLCTVSVKSLREFGVLPNSTICHSVYPRRTYVMGRAVINDILIKKSYSTHTVCAIDRSKDENNGSAYDKFEAKGIPIDVHTLKRIISSSGMDESEFSKSISYLFAKTVDPEPKDVLSLEDLSFLLNKLYTQRFQIRRICRDINAKYSEFWFKLFSLYAEKVDAKRNQVNLRNTKLDACEIFDANLMIKNFIELGQLGKAQKILSFILDRNPDILLSPKNADISTIVHFLQLRCGALAPYWKIPDNSEQKQGFLRKMVRLGAKNTSIRLSSTYKAMDHQTLLKIADLALQEKKLLNSEDLLSTLIQSFGHLGQTQILERCIEHIWQISPQEFPSHVVIKHRGCYPSSKILVSILVSFYFNDHDLHRGLSILDSFIKHYPDVKLDALFWRRLFQLSHFAWTPANDKKATSVVRCWHLMKQWYASKRLRPSVDYETLRQLYDIMKKTGNFPLGIDVLRSFKPGIERTRAENAGKVNNIIIKYQKCIIKELVNRGRFSAVREFIDNYGFDRKMTKDLNIFCANRMFLRSKKMKNKIENKKEREKVRLDSFDDDEDDGMIIGSLW", "output": "Required for translation of the mitochondrial OLI1 transcript coding for the mitochondrial ATP synthase subunit 9."}]}
+{"id": "function_test_3682", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPFIENQTTTAEPIVPVDVKGKDAFHKLVDDLSAVLGPSSGLDSDDVDPMDIQKLMEGYVSNHEEWQRYALADESRAYTRNLVDEGNGKSNLLVLVWNPGKSSPIHDHANAHCVMKILHGSLKEHRYDWPEQDKINNGEACPLTVTKETILRENEVAYMSDKLGLHKISNPDPNDFAISLHLYTPPNAAHFGCSLFDEKTGKSHHIKQCTFFSNRGLKL", "output": "Cysteine dioxygenase involved in sulfite formation from cysteine. Required for keratin degradation and plays an important role in filamentous growth and virulence."}]}
+{"id": "function_test_3683", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKTAIFTVVLALAVFAVLCLVVSTHAERHSKTDMEDSPMIQERKGLPPGKPCYGATQKIPCCGVCSHNNCT", "output": "Reversibly blocks N-type calcium channels (Cav2.2/CACNA1B) in rat dorsal root ganglion cells. Elicits no toxic symptoms in either vertebrates or invertebrates during a period of 48 hours post-injection, when it was assayed in vivo by direct injection into mice and cockroaches (By similarity)."}]}
+{"id": "function_test_3684", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGAGQSTNTSGHGASPEEMSRILAHRFASKCFTPLELTHLKDNFYSLALKQGDIHYWNEEVLSRFLGIPDGDEKFGLGTLDAGPVIFRMVSYLGAFPFQNTLAPSVLTFDAMVKVIVLLTDRYGKVLRRGKKDRIKLLFGSLADIGRKEASPITSGDKSDNDQGRPKTRSDEAGFSVDKPSNDADDYNDDDDLVLAALESLDAIEVFKHDQRIDRTAYEAHISFDTFQRLLMLFVVIAPLQSCEKTSEYFSQLNEESLKSARYCVENILTSFDIGDRTKGIDYETFYWVISTSLPYMFDPLTPLFEHLLFSKNLDLSRRKDSGTCSVSEEKQKKTEFCISPSHPPIILPGSFKPCILDSAVISHLSFFLSTSFPTPNLLQNGTRLHGVFSSDTHGESLTSFSHNVLTWDAPSILLVTGSINHSSGDEADIITVGAYIPQPWKLPASTSTSHYDTSHQSQLPYLFQLSPRYAVMQGSPSINSLKPNLPVVSFSTKSGIAIGCKIPPPTRTSMDSSRPTPAGSGSLWIDPALENAEFVMSNGLSHEEGVFLPPGIARWSPSRPPSKAESETIKISIYNIEVWGVVQTAPTPAQSPYHSRTSTANGDIPDAVARQQANWNFEAREAERRREIHLNVGGGDSEEQTGRALLEMAGIIGDSARRR", "output": "May be involved in a process influencing telomere capping."}]}
+{"id": "function_test_3685", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSKDVIEYSKLFAKLVNTNDDTKLDDTIASFLYYMFPRELFIRAISLLESSDMFIYILDRVHNKEGNEHTSLIDVLVDEFYKGSSNSLLEYRLIVKDTNDGAPPILVDIAHWFCSCEEFCKYFHEALEKTDEKEELHDVLINEVDDHLQFSDDRFAQLDPHSLSKQWYFKFDKICCSHLLAFSILLRSSINVLKFFTVNSNKVFVIAIDNIDEWLNLHINIVE", "output": "Plays a role in a RAD51/RAD54-dependent homologous recombination repair (HRR) pathway to repair MMS-induced lesions during S-phase. Required for error-free repair of spontaneous and induced DNA lesions to protect the genome from mutation (By similarity)."}]}
+{"id": "function_test_3686", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "RFKKIRRLGALPGLTSKRPRSGSDLKNQLRSGKRSQYRIRLEEKQKLRFHYGLTERQLLKYVHIAGKAKGSTGQVLLQLLEMRLDNILFRLGMASTIPGARQLVNHRHILVNGRIVDIPSYRCKPRDIITTKDKERSKVLIQNYIASSPHEELPNHLTIDPLQYKGLVNQIIDSKWVGLKIN", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; "}]}
+{"id": "function_test_3687", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDSNTVSSFQDILMRMSKMQLGASSEDLNGMITQFESLKLYRDSLGEAVMRMGDLHSLQNRNGKWREQLSQKFEEIRWLIEEVRHRLKITENSFEQITFMQALQLLLEVEQEIRTFSFQLI", "output": "Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs). Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell. Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain. This domain is believed to allow recognition of RNPs bound to the protein M1. Since protein M1 is not available in large quantities before late stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the host nucleus until sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized. Furthermore, the RNPs enter the host cytoplasm only when associated with the M1 protein that is necessary to guide them to the plasma membrane. May down-regulate viral RNA synthesis when overproduced."}]}
+{"id": "function_test_3688", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSNYKILHTSDWHIGKKIENFSILKEQKNFLYFLLEFIKKENIDLLLVAGDVYDSKRPGFEEQRLVNNFFYELSFTSCKWCVVISGNHDKKDYLSINKKLLSRFNFFLITEYDSDEQIVLLKDNGNLKFIVVCLPHINERLILGQNFDNIFGLEDQYSSKLFLENLENAYREKISNLSNFLENKYKGIPKILMAHSFFGSSKKIDTLGGSYIIPFNVFGNGFSYVALGHIHKFMKLRDNIVYSGSPMQYSFNETCDKYINVLHFNDNKLILQEAFPVPIFNKLIFAKGSLNEVLDFLANSKKEESFTIYLKIELNEAVDTSAEESIYDLARLNFMNLVSISYSLPSSQDLQDDSNFIGELEVLEMDEKYFFEKKLRWDFENGVIRDIKFKEEELISLFNEVLANGYLGEYEDK", "output": "SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity)."}]}
+{"id": "function_test_3689", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIEVGEYKVKEGLYYTKDHEWAQVLEDGTVLVGITDYAQKELGDLAYVELPEVGKEVSKGDVLCEVESVKAVSEVYAPVSGEVIEVNEELSDSPEKINEDPYGAWIAKIKPKNLEEELKELMDAEKYAEYLKTL", "output": "The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein."}]}
+{"id": "function_test_3690", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "RLFDQFFGEGMFDHDLLPFTSPTISPFYRQSLFRNFLDSSNSGISEVRSDRDKFTVHWDVKHFSPDELSVKVIDDFVEIQGKHGERQDDHGYISREFHRRYRLPSTVDQSAITCSLSADGLLTLSGPNPAGGPNGRSDRSIPVCR", "output": "Contributes to the transparency and refractive index of the lens. May act as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions."}]}
+{"id": "function_test_3691", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTKHGKRIRGIQETYDLAKSYSLGEAIDILKQCPTVRFDQTVDVSVKLGIDPRKSDQQIRGSVSLPHGTGKVLRILVFAAGDKAAEAIEAGADFVGSDDLVEKIKGGWVDFDVAVATPDMMREVGKLGKVLGPRNLMPTPKAGTVTTDVVKTVAELRKGKIEFKADRAGVCNVGVAKLSFDSAQIKENVEALCAALVKAKPATAKGQYLVNFTISSTMGPGVTVDTRELIAL", "output": "Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.; "}]}
+{"id": "function_test_3692", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "DQGAGVTYLEPSASQIGHKESIKDTARVLGRMYDGIEYRGFGQDVVEELAKYAGVPVFNGLTNEFHPTQMLADALTMREHSGKPLSQTAFAYVGDARYNMANSLLVLGAKLGMDVRIGAPKTLWPSEHIVARARAVAKETGGRILLTENAEEAVKGVDFIHTDVWVSMGEPKEAWQERIDLLKDYRVTPELMAASGNPQVKFMHCLPAFHNRETKVGEWIYETFGLNGVEVT", "output": "Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline."}]}
+{"id": "function_test_3693", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "ADAPAGFTLCKACHSVEAGKNGVGPSLAGVYGRKAGTISGFKFSDPHIKSGLTWDEPTLTKYLADPKTVIPGNKMVFAGLKNPDDVKAVIEYLKTLK", "output": "Cytochrome c2 is found mainly in purple, non-sulfur, photosynthetic bacteria where it functions as the electron donor to the oxidized bacteriochlorophyll in the photophosphorylation pathway. However, it may also have a role in the respiratory chain and is found in some non-photosynthetic bacteria."}]}
+{"id": "function_test_3694", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVTLKMAIIFLMEQIRTPFSLIWTIMSPTVLFFFLHFNEIELHYGDTAWLGKQISWFVGYISFSVVLFNYCLYLVGRRESGFIATFVHNMDGRLLFIRSQLIASLIMSILYVFFFILVVLTGFQASPDYQIVMIILKSIYINAFMMVSLTFMASFRVTFQTASTIYSVLITVCMVSGIVSLKYNEGIVYWINQVNPIAIYSTILQSDQELSLMTIFFYSIMLIISIISALTFKTEPVWSSQ", "output": "Together with two further proteins McbF and McbG this protein causes immunity to the peptide antibiotic microcin B17 (MccB17), which inhibits DNA replication in enterobacteriaceae. Immunity is determined by two different mechanisms. McbE is involved in the production of extracellular MccB17 and, in a complex with McbF it also serves as 'pump' for the export of active MccB17 from the cytoplasm to the periplasmic space."}]}
+{"id": "function_test_3695", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "ASGKGCLLGHDNSGYYQAKKLQGEDNTECDLEPHELKLSPLEIEVTDADGFTNGLAPGVADSHQTQGTKECGLLTAHGNNGLAKSGALDQNPKLLMGVFTVASSNSALTVADLTKAATSAIANTGLGQAHAAVKAIQDANPAANDNTSTSEDTAELQTAIMHLELQAATAGSRNMKEETKKIFTNKVQDTITKVLHNVYSHQITVPFVNNGKDTPLRSIPNTGELMEILAFYEQKVADNTAKTQKELTEAQQAMKTDRSGDGGCTQITEPTACNSKPFCSYNESTTDDDKKCKYNATKATENGVPVAQTQTGGSETTTEK", "output": "VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes."}]}
+{"id": "function_test_3696", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MHLLPELASHHAVSIPELLVSRDERQARQHVWLKRHPVPLVSFTVVAPGPIKDSEVTRRIFNHGVTALRALAAKQGWQIQEQAALVSASGPEGMLSIAAPARDLKLATIELEHSHPLGRLWDIDVLTPEGEILSRRDYSLPPRRCLLCEQSAAVCARGKTHQLTDLLNRMEALLNDVDACNVN", "output": "Transfers 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein."}]}
+{"id": "function_test_3697", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKAGREAGVYMRVVRNTLLRRAVEGTPFECLKDAFVGPTLIAYSMEHPGAAARLFKEFAKANAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRDAKEAA", "output": "Protein L10 is also a translational repressor protein. It controls the translation of the rplJL-rpoBC operon by binding to its mRNA (By similarity).; "}]}
+{"id": "function_test_3698", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAALHVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLVNIVSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAIKDPATFKTGWVVLLLLLVGFFVLEPLGIPVSAIAAVGALILFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAATLGTGFLTAFLSSIMNNMPTVLVGALSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWGYYFRTGIIMTLPVLFVTLAALALRLSFTL", "output": "Involved in arsenical resistance. Thought to form the channel of an arsenite pump (By similarity)."}]}
+{"id": "function_test_3699", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNKSQLIDKIAAGADISKAAAGRALDAIIASVTESLKEGDDVALVGFGTFAVKERAARTGRNPQTGKEITIAAAKVPSFRAGKALKDAVN", "output": "Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions."}]}
+{"id": "function_test_3700", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLDKIDRKLLALLQQDCTLSLQALAEAVNLTTTPCWKRLKRLEDDGILIGKVALLDPEKIGLGLTAFVLIKTQHHSSEWYCRFVTVVTEMPEVLGFWRMAGEYDYLMRVQVADMKRYDEFYKRLVNSVPGLSDVTSSFAMEQIKYTTSLPIE", "output": "Plays a role in L-cysteine detoxification. Binds to the dlsT(yhaO)-yhaM operon promoter in the presence but not absence of L-cysteine; activates transcription from the dlsT(yhaO)-yhaM operon."}]}
+{"id": "function_test_3701", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSIDRTSPLKPVSTVQPRETTDAPVTNSRAAKTTASTSTSVTLSDAQAKLMQPGSSDINLERVEALKLAIRNGELKMDTGKIADALINEAQQDLQSN", "output": "Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA (By similarity)."}]}
+{"id": "function_test_3702", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKVMRTTVATVVAATLSMSAFSVFAEASLTGAGATFPAPVYAKWADTYQKETGNKVNYQGIGSSGGVKQIIANTVDFGASDAPLSDEKLAQEGLFQFPTVIGGVVLAVNIPGLKSGELVLDGKTLGDIYLGKIKKWDDEAIAKLNPGLKLPSQNIAVVRRADGSGTSFVFTSYLAKVNEEWKNNVGTGSTVKWPIGLGGKGNDGIAAFVQRLPGAIGYVEYAYAKQNNLAYTKLISADGKPVSPTEENFANAAKGADWSKTFAQDLTNQKGEDAWPITSTTFILIHKDQKKPEQGTEVLKFFDWAYKTGAKQANDLDYASLPDSVVEQVRAAWKTNIKDSSGKPLY", "output": "Part of the ABC transporter complex PstSACB involved in phosphate import."}]}
+{"id": "function_test_3703", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "ADVPGNYPLNTNGNMYYCTILGENEFCRKVCKVHGVKYGYCFNSHCWCEYLEAKDVSVWNAAKNYCKNPVGK", "output": "Binds to sodium channels (Nav) and affects the channel activation process."}]}
+{"id": "function_test_3704", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSLLLENLIEEDTIFFAGSISEYDDLQMVIAGAKSKFPRSMLSIFNIVPRTMSKYELELIHNENITGAMFTTMYNIRNNLGLGDDKLTIEAIENYFLDPNNEVMPLIINNTDMTAVIPKKSGRRKNKNMVIFRQGSSPILCIFETRKKINIYKENMESASTEYTPIGDNKALISKYAGINVLNVYSPSTSMRLNAIYGFTNKNKLEKLSTNKELELYSSSPLQEPIRLNDFLGLLECVKKNIPLTDIPTKD", "output": "Major core structural protein."}]}
+{"id": "function_test_3705", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MACLRPLQVHNLKKGEKVNFKHYSNGDVARYDMNKNYIVNDSVPCRKCVGCRLDNSAEWGVRASLEIKSNPKHNWFVTLTYSDEHLVYNALGRPNCVPEHITKFIKSLRKYFERRGHIGIKYLASNEYGTKRMRPHYHICFFNLPLDDLEKTIDSQKGYQQWTSKTISRFWDKGFHTIGELTYHSANYTARYTTKKLGVKDYKALQLVPEKLRMSKGIGLKYFMENKERIYKEDSVLISTDKGIKRFKVPKYFDRRMEREWQDEFYLDYIKEKREKVAKRTLFQRQIVSSRSYTDYLGDEQKKLNNIVKRLTRPLKTGKK", "output": "Plays an essential role in viral DNA replication. Binds the origin of replication and cleaves the dsDNA replicative form I (RFI) and becomes covalently bound to it via phosphotyrosine bond, generating the dsDNA replicative form II (RFII). In turn, viral DNA replication initiates at the 3'-OH of the cleavage site. After one round of rolling circle synthesis, protein ORF2 is linked to the newly synthesized ssDNA and joins the ends of the displaced strand to generate a circular single-stranded molecule ready to be packed into a virion."}]}
+{"id": "function_test_3706", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSANNMRLLCLLLACYISAIVAHRPSYRSSGSDRYVDVVRASETAEAQAAALTNAAGAAASAAKLDGADWYALNRYGWEQGRPLLAKPYGPLDNLYAAALPPRSFVAEIDPVFKKSHYGGAYGGKSVTLNTGAKVAVAALN", "output": "Chorion membrane (egg shell) protein; plays a role in protecting the egg from the environment."}]}
+{"id": "function_test_3707", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKHKKKNRLVVAISVALIPYIGVTGDIPDSFRDLWGEQDEFYEVKLYGQTLGIHRIKTTPTHIKFYSPESILDKINLKKEKEKELSVFFTNSFSRNGNMSCQGNTTIQYNCNYIKTKSVDVIVDDVDNVVNLFIGNEFLDSEAHNDEYHQLSRNVKKAFIQSQTINLSDSGKYKRLSISGNSALGITDTSYAVLNWWMNYNKSNGYSNNEKTINSLYFRHDLDKRYYYQFGRMDRTDLSQSISGSFNFNLLPLPDIDGIRTGTTQSYIKNTDKFIASPVTVMLTNFSRVEAFRNDQLLGVWYLDSGVNELDTARLPYGSYDLKLKIFENTQLVREEIIPFNKGRSSIGDMQWDIFVQGGNIVNDNDRYIEKQNNHKSSINTGLRLPITKNISVQQGVSVIDNKSYYEGSLKWNSGILSGSLNSEFSFLWGDNAKGNYQSISYTDGFSLSFYHNDKRVDNCGRNYNAGWSGCYESYSASLSIPLLGWTSTLGYSDTYSESVYKSHILSEYGFYNQNIYKGRTQRWQLTSSTSLKWMDYNFMPAIGIYNSEQRQLTDKGGYISVTITRASRENSLNTGYSYNYSRGNYSSNELFVDGYMTSTNNGDYHEAGMRFNKNRHNAEGRLSGRINNRFGDLNGSFSMNKNRNTNSTNHSLTGGYNSSFALTSDGFYWGGSTAGLTKLAGGIIKVKSNDTKKNLVKVTGTLYGDYSLGSNDNAFIPVPALTPASLIIEDNNYGDNNISILAPTNNDMFMLPGNVYPVEIETKVSVSYIGRGFDPNGTPLSGAHVLNEPHVILDEDGGFSFEYTGNEKTLFLLKGRTIYTCQLGKNKVHKGIVFVGDVICDINSTSSLPDEFVKNPRVQDLLAKNDKG", "output": "May serve as anchor for the fimbriae in the outer membrane."}]}
+{"id": "function_test_3708", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTKIGLFYGTQTGNTETIAELIQKEMGGDSVVDMMDISQADVDDFRQYSCLIIGCPTWNVGELQSDWEGFYDQLDEIDFNGKKVAYFGAGDQVGYADNFQDAMGILEEKISGLGGKTVGFWPTAGYDFDESKAVKNGKFVGLALDEDNQPELTELRVKTWVSEIKPILQS", "output": "Low-potential electron donor to a number of redox enzymes."}]}
+{"id": "function_test_3709", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAVLTAVDLTNASRYAAHMHRLEFIGRWRERLPHILIDYTLRPASSEDDYYVPPKLRDRALAVKLAFSRRGCDSMSCYPFHETGVVSNQTEFAYTQTSETSVAYSQPACYHLDRAAAMREGAENEVQSAEFTYTPNNQCVLVDSTSKMYFNSPYLRTEEHTIMGVDDVPAFNVRPDPDPLFPERFKGEFNEAYCRRFGRDLMNGGCSFRWWESLIGFVLGDTIYVTFKMMANNIFSELRDFDYTAPSPLLPARPVADSNAVLAQWRAVRDRAVDWNFEKQFSEAPTLQQLGLLADNGGLMQLAYTAETGFAKTPIAYSARVTPRAVRDFGAPGRQLNDEELEAIIASFLEEYSLVFGIATDIGFDMLLTAFKTMLKKINTALIPALKRMLVSTSQRVTVRLLGETYKAAIVHSMNRIAIKTLTTAAKALTRIAIKASSVVGIVLILFTLADLVLALWDPFGYSNMFPREFPDDLSRTFLTAYFETLDANSSREIIEFLPEFFSDVVETDDDATFQSLFHLLDYVAALEVNSDGQMLHFTESNAIEDFDEATLVGQALASSSLYTRLEFMQYTFRQNTLLEMNKNNNRFNGAIASLFLTGTAVALAAFMLHKKLTFFVYFAIFLMLALYYLVKEPYEYFKTIDLLF", "output": "Essential for virulence of baculovirus occlusion bodies for insect larvae."}]}
+{"id": "function_test_3710", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MVILLQSLQKSAYGKEPWTLTQTSLETVRSAPANCFKKGPQNIEVMFDKDPENIMVYTVWTYIYYQTLDDTWNKVEGKIDYHGAYYLEGTLKVYYIQFEVDAARFGKTGIWEVHVNEDTIFAPVTSSSPAAGEGATSIDSAPESPANRQLSSTSVSSRKRTPPRTEARRYNRKESSPTTTTTRRQKRQGQRQEDTARRSRSTSRGRQEISRGGNQRRRRRSRETSISPAWGRGGRSRRGPTTRSQSKSLSRSRSRSKSRSRGSSPRGGISPADVGSSVRSLGRKHTGRLERLLEEARDPPVILLRGDANKLKCFRFRAKKKYQDLVKYYSTTWSWVGGTSNDRIGRSRLLLAFSSNTERELFIKIMKLPPGVDWSLGYLDDL", "output": "Plays a role in the initiation of viral DNA replication. A dimer of E2 interacts with a dimer of E1 in order to improve specificity of E1 DNA binding activity. Once the complex recognizes and binds DNA at specific sites, the E2 dimer is removed from DNA. E2 also regulates viral transcription through binding to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory regions of the viral genome. Activates or represses transcription depending on E2RE's position with regards to proximal promoter elements including the TATA-box. Repression occurs by sterically hindering the assembly of the transcription initiation complex."}]}
+{"id": "function_test_3711", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNMSTNYSTTNQSYKHLSEAERGEIEAYLSVGLKPAEIARRLGRNRSTITREINRGSITQVKKVNGAKGLLPTLLCRCCSITVIRHAREASYYLKLDSVSDDFMRAFTDAMREKPRVHSVDTFVHTYRLQHVDAVVPSTKTLYNYIHQGLLEIKVIDLPRRVRIRKKFTKRPSTKKHLGKSIEERPEEINNRSRFGDWEIDSVLGGKTIGEPSILTLVERQTRYAVTKKLVEKKAEYVNQAVLECMKLYPIKSITADNGNEFSSLSKIEGLDVYFAHAYSSYERGTNENFNGLLREFIPKGCSLKELNQNLLEDYTKAINERPRRIHGYQSAKKLFELTQTA", "output": "Required for the transposition of the insertion element."}]}
+{"id": "function_test_3712", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MASIDFRNKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKEQDRLEEYGLDALTGPFESIVEMACLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTHDRCVVSSLRLQEGEENLNDIRRKVRQDICHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGPVPDSHRYLMKKPGYYLSEEKYIARLRKELQLAPYSRFPLTWIMEAADDISYCVADLEDAVEKRIFSVEQLYHHLYHAWCHHEKDSLFELVVGNAWEKSRANTLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPQIFAGTFNQALLEDASGFSRLLELYKNVAVEHVFSHPDVEQLELQGYRVISGLLDIYQPLLSLSLNDFRELVEKERLKRFPIESRLFQKLSTRHRLAYVEVVSKLPTDSAEYPVLEYYYRCRLIQDYISGMTDLYAWDEYRRLMAVEQ", "output": "dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs."}]}
+{"id": "function_test_3713", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSSVTKRPRAKRIRLPLEIIDTILQYLDPILHAKVVGLTTRVKCRLLRDNNVEDYLKLTPASYHPTTDQFICNYLGITNQPMAPYLVPLLSFGKASCVFFNKCIPEDVRIVTLNWPLPLLENFLSKQFLWYKLARKLIEHERRMDRCVTPSTVQINLYDDNEDYLNCFNCFNCCKDNLVSFNCCIVDCNINDMNRCPDLQIDVYLDDNIISLYLYFLFRIYRIVKE", "output": "F-box protein that manipulates the host DNA damage response (DRR) in order to promote viral multiplication. Acts as a substrate recognition component of SKP1/Cullin/F-box (SCF) complexes for targeted protein polyubiquitination."}]}
+{"id": "function_test_3714", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "ELNPSLVISLSXGL", "output": "Not yet known."}]}
+{"id": "function_test_3715", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MHADTLDAMLHHELPHAAAGCQQAYGRIVTACQNTVTAIALAITRDVAASEDIAQEAFLRAWQRLAQLHQPASFLPWLRQITRNLARDWLRSHRHRPLSGEAADLAIAMAADPSPSPAEQALQVEEERAALEIMSALPNDSREILLLYYREGQRSQQVASLLGLSDAAVRKRLSRARATVRNELLQRFDTFARGSAPGVAFATTVTAATMLAAPGTASAAIALGGIGSLGGVGKLGASGLSGSALTSGSAAGALSVLLGMPMAIALLAITGVTLTTYMSGAYLLRFATTAREAAAIRGFTRLSTLTAALTCGAPLLLRAFGAPKWLALCVLAVGMSVVCYHTLGTLPRIMQPMLERDARRRGTTRPPLLYRCMFSRSAIAVSLAAVIVPIAYRYGVLGLV", "output": "Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in lipopolysaccharide biosynthesis and pathogenicity."}]}
+{"id": "function_test_3716", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTEQTIDNILPASKNNVKQWYVVHTASGAEKRIKEDILRKIAKQKMTDFFEDILIPVFGVSEVKRGKNVKVEKKLMPSYILIKMNMTDKSWHLVKNIPGVTGFLGSKIVPKALTESEIQNIFNNLEAEAKVAKNSKLYEVGEIVTVTDGPFETFMGTVEAIDKARNRLKVSVSIFGKATPIELNFNQVKKSD", "output": "Participates in transcription elongation, termination and antitermination."}]}
+{"id": "function_test_3717", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MATTTAGLTDLKFRVVREDFADAVAWVARSLPTRPTIPVLAGVLLTGTDEGLTISGFDYEVSAEVKVSAEIASAGSVLVSGRLLSDITKALPAKPVEVSVEGTRVSLTCGSARFSLPTLAVEDYPALPALPEETGVIASDLFAEAIGQVAVAAGRDDTLPMLTGIRVEISGESVVLAATDRFRLAVRELTWVTTAGDVEAAVLVPAKTLAEAAKAGTDGNQVHLALGSGASVGKDGLLGIRSEGKRSTTRLLDAEFPKFRQLLPAEHTAVATIGVAELTEAIKRVALVADRGAQIRMEFSDDTLKLSAGADDVGRAEEDLPVDFAGEPLTIAFNPTYLTDGLGSLHSERVTFGFTTPSRPAVLRPAGEDDGANGGSGPFPAAKTDYVYLLMPVRLPG", "output": "Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication."}]}
+{"id": "function_test_3718", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEEEVAALVIDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHHGIMIGMGQKDSYVGDEAQSKRGILTLRYPIEHGVVTNWDDMEKIWHHTFYNELRVAPEEHPVLLTEAPINPKSNREKMTQIVFETFNAPAFYVSIQAVLSLYASGRTTGIVLDSGDGVTHVVPIYEGFALPHAISRIDMAGRDLTNYLMKILAERGYSFSTTAEREIVRDIKEKLCYVALDFQQEIQTASQSSSLEKSYELPDGQVITIGNERFRAPEALFQPSVLGLESGGIHATTYNAIMKCDVDVRKDLYGNIVMSGGTTMYPGISDRMQKEITALAPSSMKVKIIAPPERKYSVWIGGSILASLSTFQQMWISKQEYDESGPSIVHRKCF", "output": "Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells."}]}
+{"id": "function_test_3719", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTPDLQLALELAEKAGKLTLDYFGRRSLQVFSKRDDTPVTEADRNAEELIRQGISAKFPDDGLFGEEFDEHPSGNGRRWIIDPIDGTRSFIHGVPLYGVMIALEVEGAMQLGVINFPALGELYQAERGSGAFMNGSPVQVSAIAENSASTVVFTEKEYLLDPPSNHPVDQLRIDAGLVRGWGDCYGHMLVASGRAEVAVDKIMSPWDCAAVIPIVEEAGGCCFDYRGRQSIIDGEGLVSANNAMGRNLIAAIGNGERDR", "output": "Catalyzes the dephosphorylation of histidinol-phosphate to histidinol, the direct precursor of histidine."}]}
+{"id": "function_test_3720", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "SPTISITAPIDVLRKTWEQERARKQMVKNREFLNSLN", "output": "Stimulates fluid secretion by the Malpighian tubules. Increases cyclic AMP production."}]}
+{"id": "function_test_3721", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLQKKKYQKKSSKIIINKKAYYNYFIEKVFQSGLVLEGWEIKSIRSGKVNISESYIINDRNEMYLCNCLIEPLQMSSNRFSCDPTRKKKLLLHKNEIDFLSLKKKNTGYTMVSLSLFWKKSWCKLEFGLAKGKTAQDKRINLKKREWEQEKLKILKKTKETY", "output": "Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation."}]}
+{"id": "function_test_3722", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSRRGTAEKKTAKSDPIYRNRLVNMLVNRILKHGKKSLAYQIIYRAVKKIQQKTETNPLSVLRQAIRGVTPDITVKARRVGGSTHQVPIEIGSTQGKALAIRWLLAASRKRPGRNMAFKLSSELVDAAKGSGDAIRKKEETHRMAEANRAFAHFR", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit."}]}
+{"id": "function_test_3723", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAQRERNREERGREERDSEFVDKLVHINRVAKVVKGGRRFGFAALVVVGDQKGRVGFGHGKAREVPEAIRKATEAAKRDMIFVPLRSGRTLHHDVEGRHGAGKVLLRAAPAGKGIIAGGPMRAVFETLGVQDVVAKSLGSSNPYNMVRATFDALKHQMHPKDIAAQRGIKYSTLQARRHDVVGSEE", "output": "With S4 and S12 plays an important role in translational accuracy.; "}]}
+{"id": "function_test_3724", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MVKSARQGAGGFWRDFKDFILRGNVVDLAVAVVIGGAFTSIVNAFVAWLMAVLLQPVLDQAGVSQLQDLPLGLGELVIAIINFLIIAFVIFLIIKAIEKMQRKKAVEEEIVAEAQPDPVLEAQTNLTDSINRLITTLENQQSSSQ", "output": "Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell."}]}
+{"id": "function_test_3725", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "YTAKQCLQAIGSCGIAGTGAGAAGGPAGAFVGAXVVXI", "output": "Bacteriocin active against Listeria monocytogenes, Pediococcus, Enterococcus, Lactobacilli and Bacilli."}]}
+{"id": "function_test_3726", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "ARAVGIDLGTTNXVXAV", "output": "Acts as a chaperone."}]}
+{"id": "function_test_3727", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MVEMRMKKCPKCGLYTLKEICPKCGEKTVIPKPPKFSLEDRWGKYRRMLKRALKNKNKAE", "output": "Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA."}]}
+{"id": "function_test_3728", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "AGLPPEEKPKLCDAACE", "output": "PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity)."}]}
+{"id": "function_test_3729", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPSIGPIPTIPDEGSRGSSATAAPRRAMASYRDTTLGGRAEGVAFSAVEDSYTSSVSLARMLYGGDLEEWVRHTRPGVSLEIQSRAPVRFPPPNNPSSRRVTVVRAPMGSGKTTALLKWLGEALDAPDISALVVSCRRSFTRTLAKRFNDAELPGFATYFTSTDYTMAGEPFRRLLVQIESLHRVDDNLLNNYDILVLDEVMSTIGQLYSPTMVHLNKVDALLTRLLKTCPRVIAMDATANAQLVDFLASARGERSVHVIINSFAAPGFSQRDGTLLRTLGTDVLRAALGFVLVDDENGTKVMETDSRPISARLREVNSAGFFGRLMDRLVAGRNVCVFSSTVSFSEIVARFCSQFTDSILVLNSLRPSEDVAFWGGVRVLIYTTVVTVGLSFDTAHFHSMFAYVKPMSHGPDMVSVYQSLGRVRELIHNELLVYVDSSGARAEPIFTPMLLNHVVSRQGGWPAEFSQVTDALCCQFKARCGPAYRTASTRGLALFVRFKYKHFFERCTLASVGDSINILYTLLESNQMRVAIEGCQFPLTAAGFCDFLQDLRLDAYAARKEIKQLRGPGGIAATPTEVFENDDVAVFIQKYLRPGVAHDEILALLVELNSPIVREQFVNVAVLGACLRLPAALESPEVFAGVYKHYASGVVPVISDAGALESVSITPDVNVLARWDLYKSCTRHARDLAWDPSRGGSGLDMSEDFITNTLSADYNRFQSLLVEIAKCNVTPLEMLAAGAVRGVTTALSGRPKSRVPLSKGEHAVSLFKVLWEDVFGAKLAKSTQTFPGGVRVKNLRKDEIVALLESVNVNHSECKTHRELYALLMCNRKLFAGPRYKLRAPKWSRNLCFLELDNTGTCKTPLDAALADLAPSAWPQVYGAVDFDAL", "output": "Functions as a docking protein to recruit essential components of the viral replication machinery to viral DNA origins. In the presence of the major DNA-binding protein, opens dsDNA leading to a conformational change in the origin that facilitates DNA unwinding and subsequent replication (By similarity)."}]}
+{"id": "function_test_3730", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "GSSGLIPFPRV", "output": "Mediates visceral muscle contractile activity (myotropic activity)."}]}
+{"id": "function_test_3731", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPRSLKKGPFVDEHLLKKVDVQNEKNTKQVIKTWSRRSTIIPDFIGHTFAVHDGRKHVPVFVTESMVGHKLGEFAPTRTFKGHIKDDRKSKRR", "output": "Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA."}]}
+{"id": "function_test_3732", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTRLVLGSASPGRLKVLRDAGIEPLVIASHVDEDVVIAALGPDAVPSDVVCVLAAAKAAQVATTLTGTQRIVAADCVVVACDSMLYIEGRLLGKPASIDEAREQWRSMAGRAGQLYTGHGVIRLQDNKTVYRAAETAITTVYFGTPSASDLEAYLASGESLRVAGGFTLDGLGGWFIDGVQGNPSNVIGLSLPLLRSLVQRCGLSVAALWAGNAGGPAHKQQ", "output": "Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids."}]}
+{"id": "function_test_3733", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAQITAAQVKELRDRTQVGMMDAKKALVAADGDMDKAIDVLREKGLAKAAKKSGNIAAEGLAEIAVNGNTAAIIEVNSETDFVASNDQFKDYVNNVAAAIAANKPADLEAAKATKMSDGQTVDEGAIALTTVIGEKISLRRFQVVEKTDNEHFGKYLHNGGQIAALTVIEGADDDTAKDVAMHVAAINPEYLDRTKVPAEELKHQTDIFTEETKNEGKPEKIVPRIVEGRVNKWLGEISLVDQEFVKDPDQTVAKYVAAKGGKVKGFVRYEVGEGIEKKQENFADEVMDQIKG", "output": "Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome."}]}
+{"id": "function_test_3734", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWNGHRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAHPIQLPIGAEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYVDQANEYREKLIEAVAETDEDLMMKYLEGEEITNDELKAAIRRATINVEFFPVLCGSAFKNKGVQLMLDAVIDYLPSPLDIPAIKGINPDTGEEETRPASDEAPFAALAFKIMTDPFVGRLTFIRVYSGILQSGSYVMNTSKGKRERIGRILQMHANSRQEIEQVYAGDIAAAIGLKDTTTGDSLTDEKAKVILESIEVPEPVIQLMVEPKTKADQDKMAIGLQKLAEEDPTFRVETNPETGETVISGMGELHLDVLVDRLKREHKVEANVGAPQVSYRETFRAATQARGFFKRQSGGKGQFGDVWIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLEESMANGVLAGYPMVDIKAKLYDGSYHDVDSSETAFKIAASLALKEAAKTAQPTILEPMMLVTITVPEENLGDVMGHVTARRGRVDGMEAHGNTQIVRAYVPLAEMFGYATTLRSATQGRGTFMMVFDHYEDVPKSVQEEIIKKNSGEA", "output": "Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome."}]}
+{"id": "function_test_3735", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MFEYLKGIVAKIDPAYVVLDVNGIGYKILCPTPYSYQENQPATIYVEQVVRDTGITLYGFLSLEDKELFLKLLSVSGIGPKSAVAIMAAEDTDSLASAIQNGEVKYLTRFPGVGKKTASQIVLDLKGKLGDYVKKSAVATDLTPSLQDALLALVALGYTQKEVDRITPKLAKLPENTADGYIKEALALLLKK", "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."}]}
+{"id": "function_test_3736", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSRSIKKGPFADASLLKKIEAQEGSEKKQVIKTWSRRSTIFPSFVGFTIAVYDGRKHVPVYITEDMVGHKLGEFVPTRTFRGHKVADKATTTVGK", "output": "Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA."}]}
+{"id": "function_test_3737", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGSKINPIGFRLGVNRDWEAKWYAARGYKETLNEDLRIRKFLDEKLKDASVSTVEIERAANRVNIAIHTARPGMVIGKGGAEVEALNKEINALTNKQVHINIVEIKKPDLEAKLVADGIARQLEARIAFRRASRQAAQRSMRAGAKGIKVQIAGRLNGADIARREWHTEGSVPLHTLRADIDYAWVNAFTTYGEIGVKVWINRGEILPGRKNQPAKRSKGGKK", "output": "Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation."}]}
+{"id": "function_test_3738", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEILAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLENGLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTALKKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPVIETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQMLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVAHIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQKLHARGPMGLKELTSYKYVVAGDGQIRE", "output": "Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate."}]}
+{"id": "function_test_3739", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFVTIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFDATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAVASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTVKENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKETILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDATNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFADYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVGLQLIGPKHSEETIYQVAAAFEATTGYHKQQPVIFGGDN", "output": "Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)."}]}
+{"id": "function_test_3740", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTLNLCVLTPNRIIWDSEVKEIILPTNSGQIGVLPNHAPIATAVDIGILRIRLDDQWVTMALMGGFARIGNNEITILVNDAERGSDIDLQEAQGTLEIAEANLNKAEGKRQVIEANLALRRARTRVEAVNTIS", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane."}]}
+{"id": "function_test_3741", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSFTFKQFHIDDQQCGMAVSTDAVLLGAWAELTQSSHILDIGAGSGLLSLMAAQRSPHHTSIIAVEIDNAAAKACQFNIKQSPWSETVQLFHGAIQDFQQRHNNNDEPLFDHIICNPPYFEQGTQAKNSARADARHTNTLSFAELQNVISQLLAPQGTASVILPLQSLASFIQQLNAYGLFVAKQLDIISIEGKVANRSILAIQHNPTTAEPQTLTNPAVETQYHQMTIRDKQGRYSETMIDLCRPFYLKL", "output": "Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)."}]}
+{"id": "function_test_3742", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAYNYLKNLVIPRLIVKHQFKLRSFSTKSLNDTKEKAPSALIPVGLLVKPTMLSEVQKPTLWEKLTKPASTSSPEQRQKELLNEMKRSTIQDFNEVRRFNGKLFYSPPRLFKEKSALWMYNFHGKSLRNQYKELYKDWQGSPFFFALFSNAFGENQCRNWIQHLAPFDYLPVRYANVQSNLIKYWLQKIFIGKVKRSIPEKCWNEYITAYDNKFSFPEIGWNNKLVGNVYLIDDSCKIRWLGTGDPTNVEIENLKTAIKFLVNKNVG", "output": "Involved in assembly of the mitochondrial F1-F0 complex."}]}
+{"id": "function_test_3743", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIEIDLTSFVIITLSLAVGLTGGYYGRRFLAESRIRTAEEEVAKMLDEAAKEVEAKKKEILLEAKDEIHRNRQDAEKDIRERRRELDRVERRIIQKEEMIDKKTENMEKKEQVLLEKEKETEKTQQDLQMVLSQQLKELERLSGLSSEEAKELLLYNVSQQIRQETAVLIRNIENEAKEEADKKAKNIVSLAIQKCAADVVSESTVSVVPLPNDEMKGRIIGREGRNIRTFEALSGVDLIIDDTPEAVILSSFDPIRREVARVALGNLVSDGRIHPARIEEMVEKARKEIEQEIREVGEQAAFEVGVHGLHPELIKLLGRLKYRTSYGQNVLRHSVEVAHLAGIMAAELEVDIMLAKRSGLLHDIGKAVDHEVSGPHVEIGVDLAKKYRENKDVIHGIEAHHGDIEPETVEAVLVQAADAISASRPGARRETLETYIKRLEKLENVAESFSGVDRTFAIQAGREIRIIVKPEEIDDLHSINLARDIAAKIEQDLDYPGQIKVVVIRETRSVEYAK", "output": "Endoribonuclease that initiates mRNA decay."}]}
+{"id": "function_test_3744", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNFNATLIGQTVAFIIFVWFCMKFVWPPLMNAIEARQKRIADGLADADRAVKDLELAQAKATDQLKEAKVTANEIIEQANKRKAQIVEEAKAEADAERAKIIAQGKAEIEAERNRVKEDLRKQVATLAIMGAEKILERSIDPAAHSDIVNKLVAEI", "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "}]}
+{"id": "function_valid_3745", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MARPVVAIIGRPNVGKSTLVNRLCRSREAIVHDQPGVTRDRTYQDGYWGDREFKVVDTGGLVFDDDSEFLPEIREQASLALAEASVALVIVDGQQGLTAADESIAEWLRTQNCKTLLAVNKCESPEQGLGMAAEFWRLGLGEPHPISAIHGAGTAELLDQVLTFLPPKDEESDEEEPIQLSIIGRPNVGKSSLLNSICGETRAIVSPIRGTTRDTIDTRIERENRRWRLIDTAGIRRRRSVNYGPEFFGINRSFKAIERSDVCVLVIDALDGVTEQDQRLAGRIEEDGRACVVVVNKWDAVEKDSHTMTAMEKELRAKLYFLDWAPMLFTSALTGQRVDSIFALAALAVEQHRRRVSTSVVNEVLKEALSWRSPPTTRGGRQGRLYYGTQVASRPPSFTLFVNEPKLFGDTYRRYVERQIREGLGFDGTPVKLFWRGKQQRDAEKELVRQQNRQG", "output": "GTPase that plays an essential role in the late steps of ribosome biogenesis."}]}
+{"id": "function_valid_3746", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIVKIEESWKEVLNNEFNKEYFKKLVKFIKHEYKTKNGKIFPPPKLIFNAFNSLPFKDIKVVIIGQDPYHGKNQANGLAFSVDSEIKIPPSLQNIFKEIEKSLKIKTIPNGDLKRWAIQGVFLINTILTVEEGKPSSHKGIGWEIFTDEVIKIISKNLKNIVFMLWGNLARSKKKLIDPSKHLILETSHPSPYSVNNGFLGSNHFINTLDYLKKHNKNKINFQ", "output": "Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine."}]}
+{"id": "function_valid_3747", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKTLIARHKAGEHIGICSVCSAHPLVIEAALAFDRNSTRKVLIEATSNQVNQFGGYTGMTPADFREFVFTIADKVGFARERIILGGDHLGPNCWQQENADAAMEKSVELVKAYVRAGFSKIHLDASMSCAGDTIPLAPETVAERAAVLCFAAESVATDCQREQLSYVIGTEVPVPGGEASAIQSVHITHVEDAANTLRTHQKAFIARGLTEALTRVIAIVVQPGVEFDHSNIIHYQPQEAQALAQWIENTRMVYEAHSTDYQTRTAYWELVRDHFAILKVGPALTFALREAIFALAQIEQELIAPENRSGCLAVIEEVMLDEPQYWKKYYRTGFNDSLLDIRYSLSDRIRYYWPHSRIKNSVETMMVNLQGVDIPLGMISQYLPKQFERIQSGELSAMPHQLIMNKIYDVLRAYRYGCAE", "output": "Component of the tagatose-1,6-bisphosphate aldolase GatYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of GatY. When expressed alone, GatZ does not show any aldolase activity. Is involved in the catabolism of galactitol."}]}
+{"id": "function_valid_3748", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRYMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKAKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPEPAVMKRLIQLGLPIALALFLEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRMPSAIILQRASR", "output": "Multidrug efflux pump that functions probably as a Na(+)/drug antiporter."}]}
+{"id": "function_valid_3749", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MFKAAINAEVFKDAIEAVSTLVDEAKFRITKDSISARAVDPANVAMVAFDLNAKAFDTFEATDGEIGIDLVRFMDILGMTARDDRLELNLNEETRKLEIRTGGLAYTLSLLDPGSIRKEPKVPALELPGKIVLNGAELKRAVKAAEKVSDHMALGVQDKTFYVEAEGDLDKVRLEIPESNLISLQATSNVRSLFSLDYLNDIVKSLGKAEQVTIDLGTDYPVKFTFSIASGNGTVIYLLAPRIESE", "output": "Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication."}]}
+{"id": "function_valid_3750", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAKFQAKSQNDAPDDGLKEKMIAVNRVTKVVKGGRILGFAALTVVGDGDGRVGMGKGKSKEVPAAVQKAMEEARRNMTKVSLKNGTIHHNVFGHWGAANVMMAPAPKGTGIIAGGPMRAVFEVMGITDIVAKSHGSSNPYNMVRATMDALNNSTTASEIAAKRGKSVEEIFG", "output": "With S4 and S12 plays an important role in translational accuracy.; "}]}
+{"id": "function_valid_3751", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MERAAKKEAVESLNGLFQTTSVAVVAHYSGLTVAQMQKLRSQMKQAGASVKVSKNRLAKIALEGTDVVAIGSLLKGPTVIATSSDPVAAPKVAVEFAKANEKFVILGGSMGKTVLNVDGVKALASLPSLDELRGKLVGLLVAPATKIAQLTTAPAAKVARVVQAYASKSEAA", "output": "Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors."}]}
+{"id": "function_valid_3752", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANITPDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLIALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGITAENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEYIKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIVSYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDMNKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR", "output": "Catalyzes the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA."}]}
+{"id": "function_valid_3753", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGKVAAKIKVMPDSPDIDLDELQERLEQSLPEGAKINGFERDDVAFGLVALLPTVIVPDDAGGTEAVEESFGDVTGVESVAVENVGRI", "output": "Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA."}]}
+{"id": "function_valid_3754", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTRTAIEIPENVSAEVSNLALTVEGPNGSVTRTLWYPSVTVSVDEDADADAVVIETDETDAKTSATVGTFESHVSNMIHGVTDGWSYEMEVYYAHFPMQVSVEGDEVIIENFLGEKASRRTPIRGDTNVQIDGEMVTLTGPSKEDVGQTAADIEQLTRVTDKDTRIFQDGVYITQKPQQGGA", "output": "This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center."}]}
+{"id": "function_valid_3755", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSKQNLIEIEGLVTESLPNAMFRVCLDNGCEVLTHISGKIRKNYIRILPGDRVKVELSPYDLTKGRITYRLRSKNTNT", "output": "One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex."}]}
+{"id": "function_valid_3756", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLLNTPAQLSLPLYLPDDETFASFYPGENPSLLAAIQSAVHQPHGSYIYFWSREGGGRSHLLHAACAELSQQGEAVGYVPLDKRAYFIPEVLEGMEQLALVCIDNIECIAGDEQWEMAMFNLYNRIVETGRTRLLITGDRPPRQLNLGLPDLASRLDWGQIYKLQPLSDDEKLQALQLRAKLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILSL", "output": "Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity)."}]}
+{"id": "function_valid_3757", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLQAIYNETKDLMQKSVQALNRDFSTLRSAKVSVNILDHIKVDYYGTPTALNQVGSVMSLDATTLQISPWEKNLLKEIERSIQEANIGVNPNNDGETIKLFFPPMTTEQRKLIAKDAKAMGEKAKVAVRNIRQDANNKVKKLEKDKEISEDESKKAQEQIQKITDEAIKKIDESVKNKEDAILKV", "output": "Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another."}]}
+{"id": "function_valid_3758", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDAVSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLDKLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEISFDDVDKVRGLDIVIVTTANTDEESRELLKGLGMPFAK", "output": "This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs."}]}
+{"id": "function_valid_3759", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEKFQRLDRSHYFLYPLIFQEYIYVLAHDHGLNGSILLENAGYDNKSSLLIVKRLIIRMYQQNHLILSVNDSKQTAFLGHNKNFYSQVMSEVSSTIMEIPLSLRLISSLERKGVVKSDNLRSIHSIFSFLEDNFSHLNYVLDILIPYPAHLEILVQALRYWIKDASSLHLLRFFLHECHNWDSLITSNSKKASSFFSKRNHRLFFFLYTSYVCEYESGFLFLRNQSSHLRSTSSGALIERIYFYGKIEHLAEVFARTFQANLWFFKDSFMHYVRYQGKSILASKGTFLLMNKRKDYFFNFWKSYFYLWSYPGRISINQLSNHSLDFLGYRSSVRLKPSMVRGQMLENTFLINNAIKKFDSIVPIMPLVGSLAKSKFCNALGHPIGKAIWADLSDSDIIERFGRIYRNLSHYHSGSSKKKSLYRVKYILRLSCARTLARKHKSTVRAFLKRFGSQLLEEFFTEEEQVFSLTFPRVSSISRRLSRRRIWYLDIVCINDLANH", "output": "Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns."}]}
+{"id": "function_valid_3760", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQRYPMTPQGHAALEAELKQLKSIDRPRITASIAEAREHGDLKENAEYHAAREQQGFCEARIRDIEAKLGGAQVIDPTTLPKDGRVIFGVSVVIENMDTEEEKQYKIVGDDEADFKAGKISVNSPIARGLIGKSEGDEARIETPKGVVEYEIMKVIYD", "output": "Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides."}]}
+{"id": "function_valid_3761", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MARVTVEDCIDKVDNRFDLVLLAAHRARMISSGSQLTIDRDNDKNPVVSLREIAEQTISPEDMREELVHSLQKFVEVDEPEPDTVPLIGSAGASVDADDTEVAVERMTEEELLKGLEGLAPREEQPEEDE", "output": "Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits."}]}
+{"id": "function_valid_3762", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTEFTTLLQQGNAWFFIPSAILLGALHGLEPGHSKTMMAAFIIAIKGTIKQAVMLGLAATISHTAVVWLIAFGGMVISKRFTAQSAEPWLQLISAVIIISTAFWMFWRTWRGERNWLENMHEHDHEHHHHDHEDHHDHGHHHHHEHGEYQDAHARAHANDIKRRFDGREVTNWQILLFGLTGGLIPCPAAITVLLICIQLKALTLGATLVVSFSLGLALTLVTVGVGAAISVQQVAKRWSGFNTLAKRAPYFSSLLIGLVGVYMGVHGFMGIMR", "output": "Efflux system for nickel and cobalt."}]}
+{"id": "function_valid_3763", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSMSDPIADLLTRIRNAQMVAKTTVSVPSSKVKVAIAQVLTEEGYIDSFKVNANDGKPELEIVLKYYAGRPVIERIERVSRPGLRVYRGSDAIPQVQNGLGVAIVTTPKGVMTDRKARATGVGGEVLCYVA", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit."}]}
+{"id": "function_valid_3764", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAKKSKIAKERKREELVNKYYELRKELKAKGDYEALRKLPRDSSPTRLTRRCKVTGRPRGVLRKFEMSRIAFREHAHKGQIPGVKKSSW", "output": "Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site."}]}
+{"id": "function_valid_3765", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRLSRYFMPILKENPKEAEIVSHRLMLRAGMIRQQSQGIYSWLPLGKRVLDKVNAIIREEQNRAGAIELSMPTLQSAELWQESGRYDAYGKEMLRIKDRQDRPMLYGPTNEEMVTDIFRSSVKSYKDLPLNLYHIQLKFRDEIRPRFGTMRSREFMMKDAYSFDLTREGAEHSYNKMFAAYLRTFERLGLRAIPMRADTGPIGGNLSHEFIILADTGESEVFCHKDFVGFDIPGENTDFDSVEGLKAIFDKWTSLYAATSEMHDEAAFNAVPEGDRLSARGIEVGHIFYFGTKYSEPMGAKVQGPDGKEHFVHMGSYGIGPTRLVPAIIEASHDDNGIIWPASVAPFDVVVINMKVGDQACDDTCELIYAALKKAGKDVLYDDTDDRAGTKFATADLIGVPVQIIAGPRAVANGEVEVKDRKTGARETMTIEAAINRFVA", "output": "Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro)."}]}
+{"id": "function_valid_3766", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTQTSPSRLHSPLDRLLVEAQRALDTVFGNPPAERPNPAADTPDIALDPEQRRHAAGLMRINHVGEVCAQGLYFGQAAVARDAHTQHHLLEAAQEETDHLAWCADRLHELDSRPSLLNPLWYAGSYALGALAGLRGDDWSLGFVVETERQVEAHLDEHLETLPDIDQRSRAILRVMKIDEARHADQAEQAGARQLPAPIPGAMALASKLMKTVAYRL", "output": "Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis."}]}
+{"id": "function_valid_3767", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAPSHWRLILNGKSTDNADLREAVGTLRKRGIQLDVRVTWEDGDAERYVSEAVADGVHTVVAAGGDGTLSEVAAALAHHERDAATLPSLGLVPLGTANDFATAANVPITPLDALTLIAERVAQPVDLLRIDAEHGPRWCANVASGGFGTQVTVETDEGLKKMLGGLAYLITGMSRLGRIDPIGARFNGPDFSWEGEFIALGLGNGRQAGGGQALCPEAVIDDGLLDVTIVPALDGEVAATLGTLVTGGKQAALERVAVRARVPWLEIVSNQPLTLNLDGEPETSRHFRIACVPARLRMHLPNDCPLLGR", "output": "Probably phosphorylates lipids; the in vivo substrate is unknown."}]}
+{"id": "function_valid_3768", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTDHRTRFLQLALGADALRFGQFTLKSGRLSPYFFNAGRFDSGTKTAQLAQCYADAIDAAGVDFDLLFGPAYKGIPLATALACAYAGRGRDLPLAFNRKEAKDHGEGGTLIGAPLAGHKVLIVDDVITAGTAIREALGIIRAAGGVPSGIVVALDRQEIASEQDRRSAAQAVATEAGIPVIAVANLSDLLAFAAENADLVDFREPLLAYRGRYGTDTTG", "output": "Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)."}]}
+{"id": "function_valid_3769", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNGIKYAVFTDKSIRLLGKNQYTFNVESGSTRTEIKHWVELFFDVKVIAMNSHRLPVKGRRVRPIMGHTMHYRRMIITLQPGYSIPPLRKKKT", "output": "Binds to 23S rRNA."}]}
+{"id": "function_valid_3770", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGISVHCDIVSAEQEIFSGLVEMVIAAGSEGDLGITPGHTPLLTALNPGPVRIIKQGGEEEVFFVTGGFLEVQPNMVTILSDSAQRAGDMDEAAALEAKKEAEKALANRGGDFEYSRAASQLAEAAARLRTIQQMRNKLKR", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane."}]}
+{"id": "function_valid_3771", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MFAIPFTASQVYSHLGLYLQPIEKLDPLTKVQYESAEKLRDIIAQLSRRSGGISLRKNLIRDIACGHKPKLNIPSLTHQVRHNREFKHGRSQFILVDSNGSDYYDGIFDDMVLILQSNFVLPNVPGIISEQLRLIVIDNDFYLKHIPSEIAILRDVLSEHMVKFSIDGVSLEDPFISKFFRKPFVLYDHTKFKKIDLTKVVLINKTGKSKAQVIDKYKLNDDAVFINYEVFDVMLQPTKRRDGDIEQFIRMRGDIETWKAKIGTTFEDNLLELFVHGVPVMNSTSQLQLDFQISDIRVASVFDDQIVCASKLNSLREQCLTESSLIRVNIIGQKGSGKSMLMKLINERGIPGISRRIICIDSDAYGKWRTQTQYIDNKFEALKLINVDNLYEIARDDSVVSFYEQFIIDQLLSHNIEISEHTNSLRFIKQLKVDILKDIGRKFKEMYLADFKEQGQFYEYLCGNMPEPSNTLLITFLHATVETSAAPGTNMNFSLNTILYPLQSILNRKRGTLVNFILNRIYDEMGTEAFTRLRPCDVWK", "output": "Minor inner capsid component. Displays NTPase and RNA 5'-triphosphatase (RTPase) activities. May function as a cofactor of polymerase VP2. Associates with microtubules and plays a role in the formation, structural organization and morphology of viral inclusions, where the assembly of cores and the replication of viral RNA occur (By similarity)."}]}
+{"id": "function_valid_3772", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MASEAPPFWWDEPDWRALALAPAAWIYGRVSGRRLIRAVPPRVSLPVLCVGNFTVGGAGKTPTAIAFARGAIARGMKPGIVSRGYGGNYSGLHLVDPGHDGARHVGDEPLLLARHAAVALSPDRVKAAEYLKSLGCDFIIMDDGFQSARLHADFSLLVVDASRGIGNGRVIPAGPLRAPLTDQMRKTDALLCIGKGNGADFVIRQAARAGRPIYHAQLRPSSSATVAGRRWLAFAGIGNPDKFYESVRQAGGEVVETHSFADHYSFEPDDIRGLVDMARRQGLGLITTAKDHVRLATMPGVPPEFLSKLAVLDVDLEFDRTDALDHILDTVVERFKSRLHG", "output": "Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)."}]}
+{"id": "function_valid_3773", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKGLIIIGSAQVNSHTSALARYLTEHFKTHDIEAEIFDLAEKPLNQLDFSGTTPSIDEIKQNMKDLKEKAMAADFLILGTPNYHGSYSGILKNALDHLNMDYFKMKPVGLIGNSGGIVSSEPLSHLRVIVRSLLGIAVPTQIATHDSDFAKNEDGSYYLNDSEFQLRARLFVDQIVSFVNNSPYEHLK", "output": "Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADPH, but not NADH, as an electron donor for its activity (By similarity)."}]}
+{"id": "function_valid_3774", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MANLKEIRDRIVSVKNTRKITEAMRLVAAAKVRRAQDQVLKSRPFADKLARVLENIQSRVQFEAVDSPLLSKRDVKTISLVCITADRGLCGGYNTNIIKKVEIRYAELIKQGYEPNLILVGKKAIGYFQNRKDRYIIKTTFKELEQVPTAKDSEGITSEVLAEFLSENADRVEIIYTKFITLVSCAPVVQTLLPLDPQGIADENDEIFRLTTKDSKLLVEKSNIEKSDSEKLPSDIVFEQSPDQLLDSLLPLYLQNQVLRALQESAASELACRMTAMNNASDNAKELASTLNLTYNKARQAAITQEILEVVGGSAV", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex."}]}
+{"id": "function_valid_3775", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGIFSIANQHIRFAVKLATAIVLALFVGFHFQLETPRWAVLTAAIVAAGPAFAAGGEPYSGAIRYRGFLRIIGTFIGCIAGLVIIIAMIRAPLLMILVCCIWAGFCTWISSLVRIENSYAWGLAGYTALIIVITIQPEPLLTPQFAVERCSEIVIGIVCAIIADLLFSPRSIKQEVDRELESLLVAQYQLMQLCIKHGDGEVVDKAWGDLVRRTTGLQGMRSNLNMESSRWARANRRLKAINTLSLTLITQSCETYLIQNTRPELITDTFREFFDTPVETAQDVHKQLKRLRRVIAWTGERETPVTIYSWVAAATRYQLLKRGVISNTKINATEEEILQGEPEVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGSGAMVMIAVVTSLAMRLPNPRMVAIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCISLAVLGFFLGIEVQQRLLGSMGALASTINIIVLDNPMTFHFSQFLDSALGQIVGCVLAFTVILLVRDKSRDRTGRVLLNQFVSAAVSAMTTNVARRKENHLPALYQQLFLLMNKFPGDLPKFRLALTMIIAHQRLRDAPIPVNEDLSAFHRQMRRTADHVISARSDDKRRRYFGQLLEELEIYQEKLRIWQAPPQVTEPVHRLAGMLHKYQHALTDS", "output": "Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell."}]}
+{"id": "function_valid_3776", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIFLTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVSTICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVKGRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN", "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins."}]}
+{"id": "function_valid_3777", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDIVSLTWAALMVVFTFSLSLVVWGRSGL", "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions."}]}
+{"id": "function_valid_3778", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MMKMEFGKELLVYMTFLVVVTPVFVQAIKKTELIPSKWLPTVSILVGAILGALATSLDGSGSLATMIWAGALAGAGGTGLFEQFTNRAKKYGKDDK", "output": "[Isoform Holin]: Accumulates harmlessly in the cytoplasmic membrane until it reaches a critical concentration that triggers the formation of micron-scale pores (holes) causing host cell membrane disruption and endolysin escape into the periplasmic space (By similarity). Determines the precise timing of host cell lysis (By similarity). Participates with the endolysin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles from the host cell (By similarity).; "}]}
+{"id": "function_valid_3779", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MALETFVNSEPFTFGVELEIQVVNTHNYDLTKAASDLMRLIQGETFPGNITPEITESMIELSTGICHSHEQAVSELHAIRDVLVKAADQLNVGLAGGGTHAFQQWSDRQIYDAPRFQYISELYGYLAKQFTVFGQHVHIGCPDPDSALFLLHSMSRFIPHFIALSASSPFVQNVDTGFHSARLNSVFAFPLSGRAPFVLTWDSFEEYFTKMVNTGVVNSMKDFYWDIRPKPGYGTIEVRVMDTPLSVDRAAAIACYIQTLARYLLTDRPLKLSEDDYLVYTFNRFEACRFGLEGTCVNPQTGERRTIAEDILDTLDRIAPHAAALGSRAALDEIGALANARVNDASWLRTVFKQEKSLNETVRQQCLRWRE", "output": "ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity."}]}
+{"id": "function_valid_3780", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MARKKISLIGGGQIGGVLAQLCALRELGDVVMFDIVEGLPQGKMLDIAEVGPVDGFDVCLKGTNSYADIAGSDVVIVTAGLPRKPGMSRDDLIEVNSKIMTQVAEGIKQYAPNSFVIVISNPLDAMVTLCQKITGFPYNRVIGQAGVLDSSRFAAFIAWELGVSVKDVVAVTLGGHGDDMVPLVRYTSVCGIPVMELLERKYKDKAKAKEVMEAMVKRTRGAGGEVVALLKTGSAFYSPASAAIAMTESILKDQKRVLPTCCFLQGEFGVNGYYVGVPAVLGENGVEQIIQFNLDAEEQAMMDKSVAAVKSLVDSLK", "output": "Catalyzes the reversible oxidation of malate to oxaloacetate."}]}
+{"id": "function_valid_3781", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEAKAVLRNTPTSPRKMRLVAGLVRGKQVNQAKAILLNSTKAASKNVMLTLKSAVSNYTLNNPDERVSDQELFVKAIFVDGGMTLKRTLPAPMGRAYRIRKRSNHLTIVVDKVKNPVIN", "output": "This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).; "}]}
+{"id": "function_valid_3782", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "METATLVAISISGLLVSFTGYALYTAFGQPSQKLRDPFEEHGD", "output": "May play a role in photosystem I and II biogenesis."}]}
+{"id": "function_valid_3783", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRFERFTVLTSPHVNKDARDQYEIRTHKRLIDIVEPTDKTVDALMRLDLAAGVDVQISLG", "output": "Involved in the binding of tRNA to the ribosomes."}]}
+{"id": "function_valid_3784", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRTSAQILPLVKDPERLEARLSEIPPEPGVYFMRDGSDRIIYIGKSRKLRSRVRSYFREGYNKTERIATMAKLVTEIEFIVTDTEAEALALEANLIKQHQPYFNVLLKDDKKYPYVCITWSEDYPRIFITRKRQLGKEKDKYYGPYTDSGLLREILRISKRIFALRQRPQPLFKDRPCLNYDLGRCPGVCQQLISPEEYRKTVQKVAMVFQGRTQELIDILSEQMEKAAEALNFEVAARIRDQIAGLKSLTAEQKVSLPDDTVSRDAIALAADAQHACIQLFQIRAGQLVGRLAFVAESHAEPGAILQRVLEEHYQTAESVEIPAEILVQHELPDAEILADVLTQRKGRKVTIFTPQRQVKAELIEMVERNAQYELQRMQKLGDRNHQATQDLAAILDLPDLPHRIEGYDISHIQGSNAVASQVVFIDGLPAKQNYRHYKIKNPTVTIGHSDDFASLAEVIQRRFRKYAEDPQLSRVGNPDWPDLIMIDGGKGQLSSVVAVLQEMNLLEDLRVISLAKRREEIFLPGESQPLKTDAEQPGVQLLRRLRDEAHRFAVSFHRQQRSDKLKRSRLDEIPGLGHHRQKQLLAHFRSVDYIRQATPAQIAEVPGIGPHLAQAIYDYFHPSHV", "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision."}]}
+{"id": "function_valid_3785", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTARVCVARIGAAHGLRGEVRLWTFTEDPMSVTRYGPLSTKDGARQLEVSHARAASDHLIATLTGVTTREEAERLNGTELYVARDKLPETDEGEFYHADLIGLAAFDAAGTALGTVAAIHNFGAGDIIEIAPARGPTLMLPFTDAVVPIVDIAGGRVVIEAPAEIDGEEPNSV", "output": "An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes."}]}
+{"id": "function_valid_3786", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTVSTERAVLAGGCFWGMQALLRRYPGVISTRVGYTGGDVPDATYRNHGDHAEAIEVNFDPTVTSYRQLLEFFFQIHDPTTEDRQGYDQGLSYRSAIFYTNEEQKRIAEETIAEIDASGLWPGYVVTDVEPAGPFWEAEPEHQDYLERVPNGYTCHFVRPNWKLPRKQDAGQTAAGGDR", "output": "Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine."}]}
+{"id": "function_valid_3787", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MYATTVKNKITQRDNYKEIMSVIVVVLLLTLTLIAIFSAIDQLGISEMGRIARDLTHFIINSLQD", "output": "Connects the signal transduction between the two-component systems EvgS/EvgA and PhoQ/PhoP, by directly interacting with PhoQ and thus activating the PhoQ/PhoP system, in response to acid stress conditions."}]}
+{"id": "function_valid_3788", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAEPSLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPLKKWWKVRVERVGIPMLTAIPLLTLPQFIMLQYVKGKAESWPGLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRIRNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGMFNFIVMQTLFYLPFFILGALAFIFPHLKALFTTPSRGCTLAAALAFVAYLLNQRYGSGDAWMYETESVITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHITSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR", "output": "Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane."}]}
+{"id": "function_valid_3789", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLAKVERIDPSELELNDKLIFINRVTKVVKGGKRMGFAALVVTGDGKNHVGIGVGKAKEVPSAISKASANAKRNLSRILLNGTTVPHEIVFKYGAAQVLLKPAAPGTGIIAGGSVRAVLESTGIKDVLTKSMGCSNKANVAKATLGGLTAMRDPKATVTKRRSSLKEEATGG", "output": "With S4 and S12 plays an important role in translational accuracy.; "}]}
+{"id": "function_valid_3790", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIKTILVVCIGNICRSPMAQALLRQALPGVSVISAGIGALSGYPADPSAVEVMAQHGIDISEHRAQQLTGSLVNRADLILVMGGAQKREIQARHPSKTGSVFRLGEMEQFDIDDPYRKQMMAFEDALAMIQRGVDAWVPRIRALG", "output": "May be involved in assembly or function of the EPS I polymerization/export complex and/or the EpsB ATPase. Alternatively it may function in the removal of the terminal phosphate from C55-isoprenyl pyrophosphate in order to recycle the C55-isoprenyl phosphate lipid carrier used in the synthesis of polysaccharide repeat units."}]}
+{"id": "function_valid_3791", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSLEPFKHSEALTFGVELELQLVNRHDYDLAPFAPDLLRALKGAQHAGDIKPEISPSMIEISTGICHTYQQALDELTTMRDLMQAASRSLNIGISGGGTHPFQQWADRIISDSPRYQYISELYGYLAKQFTVFGQHVHIGCPSADESLFLLHAIGRYVPHFVALAASSPYVQGVDTGFASARLNSVAAFPMSGRAPFLLTWDAFTAYFEKMRNTGVIESMKDFYWDIRPKPEFGTIEVRVMDTPLTVERACDIAAYIQMLARYLLLSRPFMPQEDDYLVYTFNRFQACRFGLEGEYVHPNELTRRPIAEHILSICDALVPHAEALGSMQALANIRALAENRNGDAEWLRQVDADARTQRETVRQACERWAA", "output": "ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity."}]}
+{"id": "function_valid_3792", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPRKGPAPKRQLMTDPVYGSPLVTALINKVLRDGKRSLAQSIVYNALEGAREKTGQDPLVILKRAIDNVKPTLEVRSRRVGGATYQVPVEVRASRSTTLALRWLVQYARLRREKTMTERLMNELVDASNGLGAAVKRREDTHKMAESNKAFAHYRW", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."}]}
+{"id": "function_valid_3793", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPRRRVVGQRKILPDPKFHNELLAKFINILMVDGKKSTAEKIVYGALDILAQKSEKDQLELFEEALDNIRPSVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWLVEAARKRGEKSMAQRLANEMLDASDSKGSAVKKREDVHRMADANKAFAHYRW", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."}]}
+{"id": "function_valid_3794", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIEVFLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDL", "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetG is required for either the stability or assembly of the cytochrome b6-f complex."}]}
+{"id": "function_valid_3795", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MMTLSYIDPIAFELGPISVRWYGIIIAMGILLGYFIAQASVKRIGFHQDTLVDIIFWSAIFGFIIARIYFVIFQWPYYVQHPIEIPMIWQGGIAIHGGLIGGFVTGIIICKQKNINPFQIGDVIAPSMILGQGIGRWGNFMNHEAHGGTVSKSFLENLHIPDFIINNMYIDGKYYQPTFLYESIWDVLGFVILILLRKHLRIGDTFCLYLIWYSIGRFFVEGMRTDSLMLAGDIRIAQLMSIILIIIGVVIMIVRRVKYDAPRYKAVGPLSWPSKEVK", "output": "Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins."}]}
+{"id": "function_valid_3796", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MXIAVVGAGVTGLAAAARLAAKGHQVTIFEKNEQVGGRMSQFKKDGFTFDMGPTIVMVPDVYKAVFEESGKRFEDYVDMKPLTHIFDIYFSDKDKVSVSTDLAQLSQTLEATEPGSTQGFMQFLTDVYKRYEVARKYFLERTFRKPSEFYNPLTLYRGLKLKTFNNANQLIDNYVSNEKIRKLLAFQTLYIGIDPKQGPSIYSIIPMIEMVHGVHYIKGGMYGLAQGLLQLGQDHGVKVELNADVQEIIIDPKFKRADGLRVNGDIRRFDKVLCTADFPYVAQNLMPVHSPLKNYSPEKVDNMDYSCSAFLIYAGINRQLRDKLHVHNVVFARDFRGNIDDIFSGKMPDDPSLYLYFPSVEDEALAPKDQTGMYVLMPVPELKTGEIDWNDPNMVEKAKDVIYNKLETIEALKDIRQDVVSETVFTPLDFESRYNAKFGSAFGLMPTLTQSNYYRPPNVSRDYKDLYFAGASTHPGAGVPIVLTSAKITAEAMLEDIEHGK", "output": "Involved in the biosynthesis of the yellow-orange carotenoid staphyloxanthin, which plays a role in the virulence via its protective function against oxidative stress. Catalyzes three successive dehydrogenation reactions that lead to the introduction of three double bonds into 4,4'-diapophytoene (dehydrosqualene), with 4,4'-diapophytofluene and 4,4'-diapo-zeta-carotene as intermediates, and 4,4'-diaponeurosporene (the major deep-yellow pigment in staphylococci strains) as the end product."}]}
+{"id": "function_valid_3797", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAGSLNKVILIGNVGRDPEIRTTGEGKKIINLSLATTETWKDRITSERKERTEWHRVVIFSEGLVSVVERYVTKGSKLYIEGSLQTRKWNDNSGQEKYTTEVVLQNFNSQLILLDSKNSNNHTQDSGRSEYKHPEAKNHSFDHSDLDDEIPF", "output": "Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism."}]}
+{"id": "function_valid_3798", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTGQPSTPVRPGSVVRTVRRHRGGRSATVQDMVAAEMPVAFNYNGVPFAVMMATPEDLEDFALGFSLSEGIVDHPQDLRVVAVDTFLEGASLQIEIPPERAAALDQRRRNLDGRSGCGVCGNESIEAVLRVPPVLQSALRIDVDALARALDALHARQPIAAQTGAVHAAGWADAQGMVQLVREDVGRHNALDKLIGALARARVDATQGFAVVTSRASYEMAMKAAQARIPLLAAISAPTALAISLADSAGLTLIGFARDHDCVVYSHPQRLDLGVAVGEPA", "output": "Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH."}]}
+{"id": "function_valid_3799", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNDLATYNFAYLDEQTKRMIRRAILKAIAIPGYQVPFASREMPMPYGWGTGGVQVTASILGPDDVLKVIDQGADDTTNAVSIRAFFQKVADVAVTTRTTEATIIQTRHRIPEEQLREGQTLVYQVPIPEPLRFLEPRETETRKMHALEEYGLMHVKLYEDIARNGHIATTYAYPVKVEGRYVMDPSPTPKFDNPKMHMSEALQLFGAGREKRIYAVPPYTEVVSLDFEDHPFEVQKFDKPCALCGAENVYLDEVVLDDKGGRMFVCSDTDHCEDRRAHGHAGAMLAPAAKESQEAAE", "output": "Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose 1,2-cyclic phosphate 5-phosphate (PRcP)."}]}
+{"id": "function_valid_3800", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSEIKDIVVQGLWKNNSALVQLLGLCPLLAVTSTATNALGLGLATTLVLTLTNLTVSALRRWTPAEIRIPIYVMIIASVVSAVQMLINAYAFGLYQSLGIFIPLIVTNCIVVGRAEAFAAKKGPWLSALDGFSIGMGATGAMFVLGSLREILGNGTLFDGADSLLGGWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAVKYLIDEKMKKRRAETAPSAVPAGETGKV", "output": "Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR."}]}
+{"id": "function_valid_3801", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAKQFKRKSNGVSESNRKRGRQELRKVTRTAARKQQQDENHEDDLNVNNDSEEDNSGKEIDEEDEEGERDDNRGKAYSALLTLLKSEHKEKPKNVTFGSSSQVEKANASDSEDDGIAGANVDEEEEEGEIDNNVDENEIVSESDDDDDEDATNRLSTDPFESHFNLPSDDYLAKEEKLVLKDNEKWRTVDKQTYSDLAISSLVQLPPGEPLNPPLLKSSKLSEYTIKKRVLDSYEQAYGTGLSDLESTLINPILNYRDVNFQYKSFKNKFYRRLYTLHALNHIFKTRDRILKNTAKLHAAKEDSEELELRDQGFTRPKVLIMLPTRDACYEVVEQLIKLSGTEQQENKKKFNDQFYVKATPPATKPEDFRDAFKGNNNDFFCIGLKFTRKSLKLYSSFYSSDIILASPIGLSMILENPDKKKRQYDFLSSIEVLIVDKCNQIEMQNWDHVNTVMKYLNKVPKEFHDADFSRIRMWSINDQAKLLRQTLVFCEYLTPSINNLISSKSYNLSGKVKFKPIINSENSMMNSIGLKIKQIFQRFDSQSPLQDPDSRYKYFINAILPSLLKTSSYEDGIMIFIPSYFDYLRVKNYLKTSTKFTFGSIDEYSSQSKLTKTRQEFASGKIKLLLYTERLHYFRRYEISGVKTLIMYGLPSNPLFYKELIRFIGKSVFKEECDLDLALVKILFSKWDAVNLEKIVGNERAPVLCNSMNELYEFR", "output": "DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2."}]}
+{"id": "function_valid_3802", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGVYIPPPNDKDDGDKKKQDTNSNTNQPTPPSSSSPSGSTTIYIPNPASSIPRNPKVGLIWGPLTPASDNLPALYSMIGLQFVIGCGFFKYARTLSRLRPIGGFQQQPHAHMAPKLVRTGPIWKIALSVITGSALSFGSGLELCRVTLPYDPWYDEAQHYRRMAVKNGDKPSSWFGAYRYYKPMDFKTWIDKVGDWIENVEKEIKIDDPANFANLSLELGKNSNVINVQRQPQTSGGILNKLNNKGKYLEIYTKLNENNTKRWEKLLHEDLNEVTELNKAPRLDLILEGKSDLINPEFTKSAIILGNHTMDDDDQFEMVWLNFEPWDELKLDTEYDIRLVPSYAGATEEIENEDQESPLTDNVVAKQT", "output": "Component of the mitochondrial inner membrane i-AAA protease complex required for mitochondrial inner membrane protein turnover."}]}
+{"id": "function_valid_3803", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSDLKTMMLNFGPQHPAAHGVLRLVLEMDGEIIERADPHIGLLHRGTEKLIEHKTYLQALPYFDRLDYVSPMSQEHAYSLCVEKLLQCEVPIRAKYLRVLFCELTRILNHLLNISSQALDVGAMTPLLWLFEEREKILEFYERASGARFHAAYIRPGGVAADVPEGLIEDIAKFIEQFPQYIDDVDELLTENRIWKQRTVGISEISIKQALDWGFSGPMLRAAGLAWDLRKSQPYEIYDQLDFDIPVGQNGDCYDRYLVRMEEIRQSVSLVKQCIEKIPEGPVKTEDRKISPPPRTEMKRSMEALIHHFKLYSEGYHVPEGEAYAAVEAPKGEFGVYIVSDGTNRPYRCRIRAPGFAHLQALDFMAKGHMLADVAAIIGSLDIVFGEIDR", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_valid_3804", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTPTLRRKLEALAERREELQHLLSDPDVVNNNDKFRTLSRELSQLEPVAVALEDEARAKADLSAAEAMRTDPEMRELAEEEIAAAQARLEELDTQLASLLVPRDPRDDGNLFLEVRAGTGGDEAAIFAGDLFRMYARYAERQGWKVEIESDSPGEHGGYKEVVARVVGRGAYSRLKFESGTHRVQRVPATESQGRIHTSAATVAIIPEADDVEEIVINPADLKVDTFRSSGAGGQHVNKTESAIRITHVPSGVVVECQTERSQHANRDKAMKRLKAQLLDTEHSKAAAAQAQTRKLQVGSGDRSQRIRTYSFPQGRITDHRVEGLTLYDLPNIIEGDLDALIARLLHEHQADELARLSDSP", "output": "Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA."}]}
+{"id": "function_valid_3805", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLSQTIKSGDWKGEKHVPVIEYEKEGDLVKVEVSVGKEIPHPNTPEHHIAWIQLWFHPEDGAFPILVGKVEFSNHTDPLTEPRAVFFFRTQKKGKLYALSYCNIHGLWENEVTLE", "output": "Uses electrons from reduced NADP, by way of rubredoxin and an oxidoreductase, to catalyze the reduction of superoxide to hydrogen peroxide."}]}
+{"id": "function_valid_3806", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSTAQAVKIGIAEMEVVIAPNVIRTCGLGSCVGVVIYDAGKAVAGMAHVMLPHSSMARGGVINAAKYADTAVEALVQLVIAAGGRKGMLKAKLAGGAQMFSFSTVGGDMMRIGARNVEEVKKQLERLHIPVVAEDVGGHSGRTIEFNPQTGVLSIRTAAQEIKEI", "output": "Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis."}]}
+{"id": "function_valid_3807", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSDKFKLLLKQIHFPQHEEAYNEIKSGSIESVKLFKSKRQWFFVFSFRNLLSYETFTLFDNLLHSSFDSLGAKVSYMINVEDISCDQSLLEAYFSYALDILKSSHFSIYSLFSNLGIEISNNSISVKAPAHILRENLHERFIALIADVLSNVGLSNVSISVLEDKEASSSLEEAYETNKISLQEEAESQARQALQSIVQSSPVPPPQKHQAQNFAEKQSQRVASFDKAEITPMIEVNSEENRIVFEGYIFDVEQRETKTGRIIINFKVTDYTSSFAMQRWVKDSEELVKFGMIKKGNWVRVRGRIENNPFTHSLTMNVQDIKEISHTPRKDLMPEGQKRVEFHAHTNMSTMDAIPTVEELIDTAAFWGHPAVAITDHANVQSFPHGYHKAKKAGIKAIFGLEANLVEDKVPIVYNSENLELKEATYVVFDVETTGLSAVHNDLIQIAASKMHKGNIVEQFDEFIDPGYPLSAFTTELTGITDNHVKGAKPLVQVLQEFQEFCKGAVLVAHNATFDVGFMNANYERHQLPTISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALDHHHMANYDAEATGRLLFIFIKDVFEKHGLTNLEQLNTELVSDDSYKKSRVKHATLYVQNQTGLKNIFKLVSLSNVSYFEGVARIPRKVLDEYREGIIVGSACADGEVFDTLLSHGIDKAVEVAKYYDFIEVMPPAIYAPLIAKDLIKDEEAIEQLIRDLIEVANRLDKPVLATGNVHYINPEDAIYREIIVRALGQGAMINRPIGKGENAQPAPLPEAHFRTTNEMLDEFAFLGKDLAYEIVVANTQAMANQIEEVEVVKKDLYTPYIDRAEEQVAEMTYAKAFELYGNPLPDIIDLRIEKELSSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYLCPKCQHSEFITDGSYGSGFDLPDKECSECGTEYKKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGEQYAFRAGTVGTVADRTAYGFVKGYERDYNKFYRDAEVDRLAMGVAGVKRNTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAAWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPKDIRADDPDVMKLFSGTEVLGVTPEQIGTSTGVLGIPEFGTNFVRGMVEETHPTTFAELLQLSGLSHGTDVWLGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLDPKMAFTIMERVRKGMWLKISEEERNGYIQAMRENNVPDWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAKAFELKTMSAGLDAVKARMEDIKEKRQRNEATNLENDLFTTLEIVNEMLERGFTFGQLDLYKSQATEFLIEGDTLIPPFIALEGLGENVAKQLVAAREEGEFLSKTELRKRGGLSSTLVERLDEMGILGNMPEDNQLSLFDDFF", "output": "Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity."}]}
+{"id": "function_valid_3808", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGAQVRLPPGEPCQEGYVLSLVCPNSSQAWCEITNVSQLLASPVLYTDLNSSINKLSISANVENKYSLYVGLVLAVSSSIFIGSSFILKKKGLLQLASKGITRAGQGGHSYLKEWLWWVGLLSMGVGEAANFAAYAFAPATLVTPLGALSVLISAILSSYFLNEHLNIHGKIGCILSILGSTVMVIHAPQEEEVTSLHEMEMKLRDPGFISFAVIVTVISLVLILIVAPKKGQTNILVYISICSLIGAFSVSSVKGLGIAIKELIEWKPVYKHPLVFVLLAVLVLSVTTQINYLNKALDTFNTSIVTPIYYVFFTSMVVTCSAILFQEWYGMTAGDIIGTLSGFFTIIIGIFLLHAFKNTDITWSELTSTAKKEAVSLNVSENNYVLLENLECSAPGYNDDVTLFSRTDD", "output": "Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+), Cu(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity)."}]}
+{"id": "function_valid_3809", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPIILSYSGFLLAAPIPASAPFTGLNKIRLI", "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetL is important for photoautotrophic growth as well as for electron transfer efficiency and stability of the cytochrome b6-f complex."}]}
+{"id": "function_valid_3810", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKVTKAELAHVAVKAEQYPKNQLPELALAGRSNVGKSSFINKMLNRKGLARTSGQPGKTQTLNFYEINERLYFVDVPGYGYAKVSKTERAAWGKMIETYLSEREELKAVLQLVDIRHRPSEDDQLMYNWMKHYGIPVILVATKADKIPKGKWQKQLTAIAKTLDKEASDPLLFFSSATGLGKDEAWRTILNHLKVTE", "output": "Necessary for normal cell division and for the maintenance of normal septation."}]}
+{"id": "function_valid_3811", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKTIGLDVGTKTIGVAISDAFGWTAQGLPTIQRSEDDPNRDFEALAQLIKENDVQKVVIGYPKNMNGTVGESATRSETFARTLEQQCNVQTVLWDERLTTAAAQRVLIDADVSRKKRKKAVDKMAAVFILQGYLDRQSHTLT", "output": "Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA."}]}
+{"id": "function_valid_3812", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKIRPLHDRVVVRRMEEERTTAGGIVIPDSATEKPMRGEIIAVGAGKVLENGDVRALAVKVGDVVLFGKYSGTEVKVDGKELVVMREDDIMGVIEK", "output": "Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel."}]}
+{"id": "function_valid_3813", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTKPIITFNNVSKTFEDSGTQVLKNINFDLEEGKFYTLLGASGSGKSTILNIMAGLLDASSGDIYLDGERINDLPINKRDIHTVFQNYALFPHMTVFENVAFALKLKKVDKKEIAKRVKETLKMVQLEGYENRSIQKLSGGQRQRVAIARAIINQPRVVLLDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWVFVMNEGEIVQSGTPVDIYDEPINHFVANFIGESNIINGTMIEDYLVSFNGKEFESVDGGMRPNEPVEVVIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIEGEVIGLDFTPEDLHIMRLNETEEEFDARIEEYVEMDESEDGLINAIEEERNEENL", "output": "Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system."}]}
+{"id": "function_valid_3814", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MADHMMAMNHSRFQDGTNGLHHPAHRMGMGQFPSPHHHQHTFNSLMGEHMHYVPGNMNSNNSIRHAMVTGNVNGGHPNGSIAPAARFNNSQFMGPPVTNQGAQLTASMQLQKLNNQYFTHQPYPHNHYIPDLHPTNHPLNGTNQHFKECNPKHSTGLPPSVSHVPAAILPPGVIDTDFIDEEVLMSLVIEMGLDRIKELPELWLGQNEFDFMTDFVCKQPNRVSC", "output": "Transcriptional coactivator or corepressor of the p300/CBP-mediated transcription complex. May be involved in sex determination, early gonad development, left-right patterning during embryogenesis and differentiation of the adrenal cortex (By similarity)."}]}
+{"id": "function_valid_3815", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSSGVQGGPAANANAYQTHPLRDAASALGTLSPQAYVDVVSAAQRNFLERMSQLASEQCDAQPAAHDARLDDRPALRAPQERDAPPLGASDTGSRASGAAKLTELLGVLMSVISASSLDELKQRSDIWNQMSKAAQDNLSRLSDAFQRATDEAKAAADAAEQAAAAAKQAGADAKAADAAVDAAQKRYDDAVKQGLPDDRLQSLKAALEQARQQAGDAHGRADALQADATKKLDAASALATQARACEQQVDDAVNQATQQYGASASLRTPQSPRLSGAAELTAVLGKLQELISSGNVKELESKQKLFTEMQAKREAELQKKSDEYQAQVKKAEEMQKTMGCIGKIVGWVITAVSFAAAAFTGGASLALAAVGLALAVGDEISRATTGVSFMDKLMQPVMDAILKPLMEMISSLITKALVACGVDQQKAELAGAILGAVVTGVALVAAAFVGASAVKAVASKVIDAMAGQLTKLMDSAIGKMLVQLIEKFSEKSGLQALGSRTATAMTRMRRAIGVEAKEDGMLLANRFEKAGTVMNVGNQVSQAAGGIVVGVERAKAMGLLADVKEAMYDIKLLGDLLKQAVDAFAEHNRVLAQLMQQMSDAGEMQTSTGKLILRNARAV", "output": "Plays a role in the bacterium-induced formation of multinucleated giant cell (MNGC), which is formed after host cell fusion, as well as in the intercellular spreading of bacteria and in the induction of apoptosis in macrophages. May act in concert with other effector proteins to induce fusion of host cell membranes (By similarity)."}]}
+{"id": "function_valid_3816", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAKESMKAREIKRAKLVAKYAEKRAALKQIVRTGDPAEAFEAAQKLQELPKNSNPIRMHNRCKLTGRPKGYIRQFGVSRIQFREMASNGLIPGVKKASW", "output": "Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site."}]}
+{"id": "function_valid_3817", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTDTILDPYFGEFGGMYVPEILIPVLKQLEKAFVEAQQDPAFQTEFLDLLKNYAGRPTALTLCRNLTKGTKTKLYLKREDLLHGGAHKTNQVLGQILLAKRMGKTRIIAETGAGQHGVATALACAMLGMPCRIYMGAKDVERQSPNVFRMRLMGAEVFPVTKGSSTLKDACCEAMRDWAANYENTHYLIGTAAGPHPFPTIVREFQKMIGEETKAQILQREGRLPDAVIACVGGGSNAIGMFTDFINETSVRLIGVEPAGKGIETGEHGAPLGHGKPGIYFGMKSPIMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSIGRAEYPSITDDEALEAFKELAQHEGIIPALESSHALAYALKMARQNPMREQLLVVNLSGRGDKDIFTVDKIFSERGML", "output": "The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine."}]}
+{"id": "function_valid_3818", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGYSYTEKKRIRKDFGKRPQVLNVPYLLTIQLDSFEKFIQRDPEGQQGLEAAFRSVFPIVSNNGSTELQYVSYKLGEPVFDVRECQIRGTTFAAPLRVNLRLVSYDRDAAPGTIKDIKEQDVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFARIDRRRKLPATIILRALGYSTEEILDLFFEKIQFEIQDNKLLMALVPERLRGETASFDIEANGKVYVERGRRITARHIRTLEKDNVTKIDVPTEYIVGKVSAKDYIDLESGELVCPANMEISLDILAKLAQAGYKSIETLFTNDLDFGPYISETLRVDPSSDRLSALVEIYRMMRPGEPPTKEAAEALFDNLFFSAERYDLSAVGRMKFNRSLGLAEGVGNGVLSKEDIVGVMKKLIDIRNGRGEVDDIDHLGNRRIRSVGEMAENQFRIGLVRVERAVKERLSLGDLDAVTPQDLINAKPVSAAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLSVYARTNNYGFLETPYRKVVDGQVTEEIEYLSAIEEGNYVIAQANASLDEDFRFTDAFVTCRGEHGESGLYRPEEIQYMDVSPQQVVSVAAALIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMEKPIALDSGVAVVAKRGGIIQYVDASRIVVKVNEDETIPGEAGIDIYNLIKYTRSNQNTCINQIPCVNLGEPIGRGEVLADGPSTDLGELALGQNIRVAFMPWNGYNFEDSMLVSERVVQQDRFTTIHIQELSCVARDTKLGAEEITADIPNVGETALSKLDESGIVYVGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNSVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKEAKKDIAEELEILEAGLFSRVRNLLIDGGVDAKELDRLDRTKWLEQTLNDEAKQNQLEQLAEQYEELRKDFEHKLEVKRGKIIQGDDLAPGVLKVVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPVEDMPYDENGQPVEIVLNPLGVPSRMNIGQILETHLGLAAKGIGEQINRMLKEKQEIEKLRGYIQKAYDLGGGSQKVDLNTFTDEEVMRLAQNLRKGMPLATPVFDGAEEKEIKDLLELGGLPTSGQITLYDGRTGEKFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVSGTHQMDPGTPESFNVIMKEIRSLGINIDLDEE", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_valid_3819", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKSIGCDIIKVGRFKNFLENKKKLERFFTHKEIENFKLKGGSVIESLAGKFAAKESLIKALSPLLQHKIHYGLKDIEVIKSLKGNAKFYLHNEIEKFAIKMNLKIYLTISHEKEYAIAFVMVEN", "output": "Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein."}]}
+{"id": "function_valid_3820", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSQSPIELKGSSFTLSVVHLHDSRPEVIRQALQEKVDQAPAFLKNAPVVINVATLPNGANWKDLQQAVTSAGLRIVGISGCQDERQKRAIARAGLPLLSEGKGQKLAPEPVISPPENVPTQTRIINTPVRSGQQIYARNCDLIVISSVSAGAELIADGNIHIYGMMRGRALAGASGDAKCQIFCTHLGAELVSIAGQYWLSDQIPLEYFGQAARLYLQDNTLTIQPLN", "output": "Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization."}]}
+{"id": "function_valid_3821", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAITAAEVKKLRDATGAGMMDAKKALTEADGDFDKAVDILRVSGAAKAAKRSDREASNGLVAAAGSSLVHIGSETDFVAKNEEFIAAAHEIAEAADKAGADSKDAANAAALADGTTVGDKLGELAAKIGEKIELANAAHFDGNAHVYLHRRSQDLPPQVGVMVEYEGDNIEAVHGVCLQIAAMSPRWLSRDEVPADVVEHERTVAADIAREEGKPEKIIDRIVEGRLGGFFKENCLLDQPAISDDKKTVAQTLEAAGVTLKRFVRFSAGE", "output": "Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome."}]}
+{"id": "function_valid_3822", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAAEVTETAQPVETAASTDNNREQREPRRGGRERNPNRDRGNRDADKSQFLERVVTINRVSKVVKGGRRFSFTALVVVGDGNGLVGVGYGKAREVPLAISKGVEEAKKNFFRVPRVANTIPHPVQGEAAAGVVLLRPAAAGTGVIAGGPVRAVLECAGIHDVLSKSLGSSNTINIVHATVEALQQLEEPRAVAARRGLDYDRVAPEKLLQIEARAAEAAAAAKKAGAEKVGA", "output": "With S4 and S12 plays an important role in translational accuracy.; "}]}
+{"id": "function_valid_3823", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLSSVVIAASEEQHNPLIPEPADIVGSLICFVVILFFFWKLVLPRVKKLLDERAEAIEGNIAKADEAQHKAEALLEEYTAQLAEARADAAKIREQARTDGQKIVAEAKDTATAEAARVTASAQAQIEAERQTALVSLRGEVGSLAIDIASGVVGEVLTEDKKAQAIVDRFLADLEASEKATSNEKAGTAN", "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "}]}
+{"id": "function_valid_3824", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEYDDKLVRFRQGHLNPFDKQGEAERQPAACETEPSKDFPTSSPLSVPEFHCPDRVMDLGVSEDHFSRPVGLFLASDIQQLRQAIEECKQEILELPEHSDRQKDAVVRLIHLRLKLQELNDPLEDEPNLRILLEHRFYKEKSKSVKHLCDKCSTFIWGLIQTWYTCTGCSYRCHSKCLNLITKPCVRSKVSHQAEYELSICPEAGLDSQDYRCAECRTPISLRSVPSEARQCDYTGQYYCISCHWNDIAVIPARAIHNWDFEPHKVSRCSMRYLALMLGRPVLKLREINPLLFNYVEELVEIRKLRQDILLMKPYFITCKEAMEARLLLQLQDRQHFVENDDMYSLQDLLDISSGRLGCSLTEIHTTFAKHIKLDCERCQAKGFVCELCKEGDILFPFDSHTSVCQDCAAVFHRDCYYDNSTSCPRCTRLNLRKQVQNPGEEP", "output": "Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts. Involved in bone resorption."}]}
+{"id": "function_valid_3825", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTDLTTLTIAQARDALKKRELKATELTEAYLKAIELANPILNTYVAITAEQAMKMAAKSDSRLAKGHGGILEGIPLGIKDLFATQDVHTQACSYILDGFKPHYESTVTANLWRDGAVMLGKLNMDEFAMGSSNETSYYGPVISPWRKKDSNEKLVPGGSSGGSAAAVAAGLCVGATATDTGGSIRQPAAFTGTVGIKPTYGRCSRWGTIAFASSLDQAGPIGRNVRDCAILLKSMASFDEKDSTSVNLPVPDYESYIGQSIKGMKIGIPKEYYLEGMSPEIVELWQKGINWLKEAGAEIKNISLPHTKYALPAYYIVAPAEASSNLARYDGVRFGLRIPGKDVIEMYENTRSVGFGNEVKRRILIGTYVLSSGYYDAYYLKAQKVRTLVKRDFDQCFSSGVDAILTPATPTPAFGIADEKIKNDTVAMYLNDIFTVPVNMAGLPGISVPSGLSSNGLPLGLQLIGKPFAEEVIFQIAHIIEQAAGMFSAEKWWT", "output": "Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)."}]}
+{"id": "function_valid_3826", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MATFVSELEAAKKSLSEALGENVKQYWANLKLWFKQKISKEEFDIEARRLLTQENVHSHNDFLLAILTRCQILISAPEGSGSLNSATKPGKPKGKKKISSVRQKFDHRFQPQNPLAGAQQFVSRDPQEDDELKLCSHTMSLPTRGQLEGRMIVTAFEHGLDNVTEEAVTIVICALEKHLKDLLTSVVSRRKAHRLKDGHFRYAFGCNVNPQPYLRNSLAAYNQLIECPPVLSSPTGTPNSGTYVHPDDAEQQAALLLACSGDNLPASLPPVNMYDLLEGLQVHREVIPSHTVYALNMERILMKLWHPNREELQQDEIHRQRLAAKEGLLLC", "output": "Probably involved in transcriptional regulation."}]}
+{"id": "function_valid_3827", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKTPPVLKRRREGVTDYRKRYRLVISRETRAVIRQTRKGLIIQLVDYVPEGDHVLVTVTNKTLKKALNIDGNNIQMYYLAGYMAAKKGISLGISGAVVDTGRAIFRKGGRIAAAIKGLIDGGLEINADEDIFPDESRLNGEHLKQRLDINEIKSKIGE", "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."}]}
+{"id": "function_valid_3828", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSDANVPLSFSDVAANKVKTLIAEEENPELKLRVYITGGGCSGFQYGFTFDEKVNDGDMTIENSGVTLVVDPMSLQYLVGGIVDYTEGLEGSRFFVNNPNATTTCGCGASFSV", "output": "Required for insertion of 4Fe-4S clusters for at least IspG."}]}
+{"id": "function_valid_3829", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLYAGFMRNHLNGDSVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWIAAMEDVLKVESQNKIPELNEYQCGTAAMHSLKEAQQIAKNILDAGVSVNKNDELALPESMLKELRID", "output": "Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD)."}]}
+{"id": "function_valid_3830", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTRVRRGYIARRRRTKIRLFASTFRGAHSRLTRTATQQKMRALVSIYRDRGRQKREFRRLWIARINAATHENGVSYSRLINDLYKRQLLLNRKIPAQIARYNLNSLYMISNEIIKEKRD", "output": "Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit."}]}
+{"id": "function_valid_3831", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MARIAGIDLPRNKRIEIALTYIFGIGRTTAQRILAETGVSADTRTDNLAESEVAKIRDYIDKNLKVEGDLRRDVSMDIKRLMDLGCYRGLRHRKGLPVRGQRTKTNARTRKGPARTVAGKKK", "output": "Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites."}]}
+{"id": "function_valid_3832", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTEYFEVGKILSPHGLKGEVKVNATTDFPEERLATGSRLFIKNNKQYEELIVENTRRHKQFYLVKFEKIDDIDQAEKICSKELYVAETDQQELPEGSYYFKDILNCPVYDAETGEKLGVLENIETPGANDIWEIKPEKGKSFWIPNIESVVKKVDLANKRIEVTLLEGLRDEN", "output": "An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes."}]}
+{"id": "function_valid_3833", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGVSLLWALLQDMVLAAIPALGFAMVFNVPVRALRYCALLGAIGHGSRMLMIHFGMNIELASLVASIMIGINWSRWLLAHPKVFTVAAVIPMFPGISAYTAMISVVEISHLGYSEALMSTMVTNFLKASFIVGALSIGLSLPGLWLYRKRPGV", "output": "Involved in succinate export with YjjP. Both proteins are required for export."}]}
+{"id": "function_valid_3834", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSAQPVDIQIFGRSLRVNCPPDQRDALNQAADDLNQRLQDLKVRTRVTNTEQLVFIAALNISYELTQEKAKTRDYAASMEQRIRMLQQTIEQALLDQGRITEKTGQNFE", "output": "Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division."}]}
+{"id": "function_valid_3835", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLQPTRLKYRKQQKGRNTGIATRGNKVSFGEFGLKAVGRGRLTARQIEAARRAMTRHIKRGGRIWIRVFPDKPITEKPIQVRMGGGKGNVEYYIAEIKPGKVLYEMDGVPEELAREAFELAAAKLPIPTTFVVRQVGQ", "output": "Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs."}]}
+{"id": "function_valid_3836", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEINRDEFKEVVVNIGRVTKVVKGGRRFRFNALVVVGNKNGLVGFGLGKAKEVPDAIKKAVDDAFKNIIKVNVKGTTIAHDIEHKYNASKILLKPASEGTGVIAGGSARPVIELAGIKDILTKSLGSNNPYNVVRATIDALSRIKA", "output": "With S4 and S12 plays an important role in translational accuracy.; "}]}
+{"id": "function_valid_3837", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLVLSRKKNESIVINNDIKIVVVEIRGDKVRLGVEAPREVPVHRREVYDAIQRNNEAFDANAPADSNDVS", "output": "A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW."}]}
+{"id": "function_valid_3838", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MQNFTVHQGVVATLDRANVDTDQIIPKQFLKRIERTGFGQFLFFDWRFLEDGETENPDFELNRINVKGASILLTRQNFGSGSSREHAVWALDDYGFRAVIAPSFADIFFNNCFKNGVLPIALSEEDVEELFQRAEKGNPYQLTVDLENQVITDGQGFERSFEVDASRRHNMLHGLDDIAQTLLHEDKITAFEEARG", "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."}]}
+{"id": "function_valid_3839", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDPQLPEPEPLIALIEALRRLPGVGVRSARRMAYHLLQHDLQGADMLGRALSAAVQHLRHCARCNSFTEDEVCATCANPKRDPGLLCIVETPADQNMIESSHGYRGLYYVLMGRIAPLEGVGPRELDFQRVIERACDGVVQEVILATNFTAEGETTAHFLDDALSERGLKVTRLARGVPAGSELEYVDAGTIAWALMERRST", "output": "May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO."}]}
+{"id": "function_valid_3840", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNIPQEVARRRTFAIISHPDAGKTTLTEKLLLFAGAIQIAGSVKARKASRHASSDWMEIEKQRGISVASSVMQMEYRDCVINLLDTPGHQDFSEDTYRVLTAVDAALMVIDAANGVEPQTIRLLQVCRARNTPIITFINKLDREVREPLELLSEIEGHLGMDTVPFSWPVGMGKAFGGVFDIRRNRMRIFRAGQERRGEDDEFIDGLDNPEIPRRFGAAFAQASGEIELINEAAPAFDREAFLAGKQTPVFFGSAINNFGVQEVLDALVDQAPAPGPRQALEREVRPDEPKFTGVVFKVQANMDPAHRDRVAFVRVSSGRFERGMRLKVARTGKEMRPNNVVSFLSQRRELLDEAYAGDVIGIPNHGVLQLGDVLTEGESLRFTGLPFFAPELFQAVEVKDPLRTKQLRVGLTQLGEEGAIQVFRPEAAGGALLLGAVGQLQFEVVAHRLKTEYGVDARMMPSRYTSARWITSDDPRALRKFMDANAAHIAYDVVDAAAFLITSPAQLRVAEDLYPNVKFHALREHGGKVFGDKA", "output": "Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP."}]}
+{"id": "function_valid_3841", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSNPQQLRYSKEHEWLSGAEDGVSTVGITEHAANALGDVVYVQLPEVGDTVTAGETCGELESTKSVSDLYSPVTGEVVEANQDVVDDPSLVNSAPFEGGWLFKVRVAEEPKDLLSADEYTEFSGS", "output": "The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein."}]}
+{"id": "function_valid_3842", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRDYKQLNGLALAYVGDAIYEIYIRDYLVSLGQTKPNVLHRMATHYVSAKAQASLMQAMLAGEMLTEEEEVMYKRGRNAKSHTFAKNADVTTYRVATGFESLMGYLHLTQQKERLEELINWCIKKVGETNEK", "output": "Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors."}]}
+{"id": "function_valid_3843", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTMTDPLSDMFSRIRNANQVLHKKVTVPSSRLKVSIADLLKREGYILDYSVIDEHPGQLLVIELKYGPDKSRALVGLKRVSKPGLRVYAKSSNLPEVFGGLGIAILSTSSGLLTCSQARKKGVGGEVLAYAW", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit."}]}
+{"id": "function_valid_3844", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAKLTKRMRVIREKVDVTKEYEINEAVALLQELATAKFVESVDVAVNLGIDARKSDQNVRGATVLPHGTGRDIRVAVFTQGANAEAAKEAGADIVGMEDLAEQVKKGEMNFDVVVASPDAMRVVGQLGTILGPRGLMPNPKVGTVTPNVAEAVKNAKAGQVRYRNDKNGIIHTTIGKANFSAEQIKENLEALLVALKKAKPSSAKGTFLKKVSISTTMGAGVAVDQASLNTQA", "output": "Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.; "}]}
+{"id": "function_valid_3845", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGKIIGIDLGTTNSCVSILENGNVKVIENAEGARTTPSIVAYANDGEILVGQSAKRQAVTNPHNTLFAVKRLIGRRFEEDVVQKDIKLVPYKIVKANNGDAWVEAAGKEMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDSQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKAKGDHTVIVYDLGGGTFDVSVIEIAEVDGEHQFEVLATNGDTFLGGEDFDMRLIDYLVDEFKKESGMDLKNDPLALQRLKEAAEKAKIELSSAQSTDVNLPYITADATGPKHLNVKISRAKLESLVEDLVKRTIEPCRIALKDAGIDASKIDDVILVGGQTRMPLVQKEVADFFGKEARKDVNPDEAVAMGAAIQGAVLAGDVKDVLLLDVSPLTLGIETMGGVMTALIEKNTTIPTKKSQVFSTADDNQSAVTIHVLQGERKQAAQNKSLGKFDLADIPPAPRGVPQIEVTFDIDANGILHVGAKDKATGKTQSIVIKANSGLSDEEIERMVRDAEANAEEDRKFEELAAARNQGDALVHSTRKMVADAGDKVTAEEKTAIEAAVVALEAAVKGDDKAAIDAKVEELSKVSAPVAQKMYAEQSAEQPQGGAQQAEPEAKHDDVVDAEFEEVKDNNKQ", "output": "Acts as a chaperone."}]}
+{"id": "function_valid_3846", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEMERINEDTIRVVIGNDDLNERGIRVLDLLGNHKQIESFFYSILEEVDVDHQFQDNDAVTFQVLPNRNGLELFISKNSDNLQDTIAKATQSPDQSDDSDSQDDVSDYLKRKLMQTDTNQVEDGQGIAHNPTKDTNDLDPYLDDPDTPTKEYVLKFDQFEDLVSLAQLFRPEGLASNLFKYRDQYYLELVFFVDQSSTATIKDDVAVALEYAHLANISADVLLEHGEKIMSNAALETIRHYFK", "output": "Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis."}]}
+{"id": "function_valid_3847", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIQMQTNLDVADNSGARRVMCIKVLGGSKRRYATIGDIIVVSIKEAIPRGKVKKGDVMKAVVVRVRKDIRRADGSVIRFDRNAAVLINNQSEPVGTRIFGPVPRELRAKNHMKIISLAPEVL", "output": "Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome."}]}
+{"id": "function_valid_3848", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSDDNSVTKVAAFYQFAALPDYRELREPLRAFCAGLALKGSVLLAQEGINGTIAGAPDAIDAFAHELAHGTMFGGRLDNLELKFSTAEAMPFGRLKVRLKKEIVTLGDAAADPTRQVGTYVDAAAWNALIAAPDTLVLDTRNAFEVAMGTFEGAVDPGIKSFGQFKDFAAERLDPAKHRRIAMFCTGGIRCEKASAHLLARGFAEVYHLKGGILKYLEEVPEAQSRWRGECFVFDERVALGHGLRERDKDATRDQ", "output": "Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs."}]}
+{"id": "function_valid_3849", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MISLMEARNLRKERTGVVLSNKMEKTITVAAKFKEKHPIYGKFVSKTKKYHAHDEKNECNIGDTVRIMETRPLSKTKRWRLVEIIERAK", "output": "One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA."}]}
+{"id": "function_valid_3850", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKTLLLTLVVVAIVCLDLGYTLTCLICPEKDCQKVHTCRNEEKICVKRFYDKNQLGWRAQRGCAVSCPKAKPNETVQCCSTDKCNK", "output": "Binds with low affinity to muscular (alpha-1-beta-1-delta-epsilon/CHRNA1-CHRNB1-CHRND-CHRNE) and very low affinity to neuronal (alpha-7/CHRNA7) nicotinic acetylcholine receptor (nAChR)."}]}
+{"id": "function_valid_3851", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTQIFDSVSFLKTVTHQPGVYRMYNAEAVVIYVGKAKDLKKRLSSYFRKKVDSEKTKALVSNIAKIDVTVTHTETEALILEHNYIKQYLPKYNVLLRDDKSYPYIFLSAHRHPRVSLHRGAKKRKGEYFGPYPDSGAVRETLHLIQKIFPVRQCEDTVYANRTRPCLMYQIGRCAGPCVSSVISDVDYAELVGYLRLFLQGKDNQVLELLVQKMEIASQQLKFEDAAKFRDQIQAIRRVQEQQYVSEDSQEDMDVLGFAQENGIACIHILMIRQGKVLGSRSHFPKIPQNTNAQEVFDSFLTQYYLSHNEARTIPSRIILNQELAADVEAIQLALSDVAGRKVQFHTSPSGSRGRYLKLSNTNALTAMTTKINHKMTINQRFKALRDVLAMDSIARMECFDISHTMGESTIASCVVFNSEGPVKQEYRRYNITGITGGDDYAAMGQALERRYAKQLDVEKIPDIIFIDGGKGQLNRAHEIIVQYWGDWPKRPVMIGIAKGVTRKPGLETLITVDGDEFHLPSDDPALHLIQHIRDESHNHAIAGHRAKRGKTRKTSALEGIEGVGPKRRQALLKYTGGLQELKRASVEEIAKVPGISHSLAEIIYQALKQ", "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision."}]}
+{"id": "function_valid_3852", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MMATLTTAISPQGPYVGRFAPSPSGALHFGSLVAALGSYLRARSLGGKWLIRIEDIDPPREVKGAADDILRTLEAYGFEWDDTVLYQSARTDAYQAKLDQLLAQDDAYFCQCSRKQIQAMGGIYDGRCHQLATPHQSGAIRLVNRAQVAEFTDNLMGKVVVDHDFATEDFIIKRSDGLYAYQLAVVLDDAHQGISEVVRGCDLIEASCRQLSLYQSLGLTAPQWLHLPLACLTPGFKLSKQNHAQAIDKQHPQASLNAALTFLGQSTVEPTSAAQMLAQAVAQFELTAVPKQREIILTA", "output": "Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon."}]}
+{"id": "function_valid_3853", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MANKTVLFNKHLESNAKMVDFHGWDMPLNYGSQIEEHHAVRQDAGMFDVSHMTVVDVTGTDACAFLRKLLANDVAKLKVPGKALYGGMLDDNAGIIDDLITYYLTDTFYRVVVNSATREKDLAWIAKQSQGFDVTVTERPELAMIAVQGPNAKAKAAAVFSSEQNAAIEGMKPFFGKQAGSLFIATTGYTGEAGYEIIVPETEAEALWQALLDQGVKPCGLGARDTLRLEAGMNLYGLDMDETINPLAANMGWTIAWEPTDRDFIGRKALEALRDAGTDKLVGLVMEEKGVLRHDMPVFFTDAAGVEQQGVITSGTFSPTLGYSIAMARVPSSIGDTAEVEMRKKRVAVRVVAPNFVRNGKQAF", "output": "The glycine cleavage system catalyzes the degradation of glycine."}]}
+{"id": "function_valid_3854", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIDPGHGGQDPGAINSLGLQEKKITLKIGIKLKNLLQNSDLFYPVLTRNDDSYVSLKKRRDFLKNNHVSFLISIHADSSKKRYVSGASIWITTNDRMHREINNFIKNREENIYFPKNIQNLIQKNKHDFFLKKTVLDLQFNNFQKMEINLSRYIFQQLKKIIKLDKINLNYASLGILSSINTPSMLIETGFITNFLEEKKLRTNKYQNKIANAIYIALKNYFQDRLLSNLRNT", "output": "Cell-wall hydrolase involved in septum cleavage during cell division."}]}
+{"id": "function_valid_3855", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MHEMSIAMSVVEAVVDKAREEGGGKITGIDLVVGRLAGVEVESLKFCFGAAARGTLAEGAELVIEEPEGRGRCEACGAEFPVTSFYAKCSACGQFRVKIESGRELAVRSFTIE", "output": "Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase."}]}
+{"id": "function_valid_3856", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGLTKEHKTEIITKFGDSATDTGKAEVQVALFTRRITDLTGHLQQHPKDKHSRRGLLMLVGKRKRVLNYLKKVDIERYRKVLADLDLRK", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.; "}]}
+{"id": "function_valid_3857", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDEFHRYGKEDSSWQQCFLYPLFFQEDLYAISHDHYLDGSSSSEPMEHFSFNDQLSFLTVKRLIGRIREQNHSIGLFVNCDPNPLVDRNKSSYFESVLEGLTLVLEVPFSTRSKYSVQGIKEWKSFRSIHSIFPFLEEKFPHSNYILDTRIPYSIHPEFLVRTFRRWIQDAPSLHPLRSVLYEYRNSPENLQRSIIVAPRVNTRFFLFLWNHYVYECESILVPLLKRSFQSRSSSHGSFPERTLFDRKIKHIIRISHRNSLKSIWSLKDPKIHYVRYGERFIIAIKGTHLLVKKCRYYLPIFRQCYFHLWSEPYRVCSHQLSKNCSSFPGYSLRVRMKPLLVRTKMLGELFITDLITDEFYPIVPIVSIIGLLAREKFCDISGRPISKLAWTSLTDDDILDRFDRIWRNFFHYYSGSFGRDGLYRIKYILSLSCAKTLACKHKSTIRVVRKELGPELFKKSFSKEREFDSPAFSSKAVARSQRERIWHSDIPQINPLANSWQKIQDLKIKNLFDQ", "output": "Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns."}]}
+{"id": "function_valid_3858", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNKGEDNLVRTSITVPEQLLQKVNELIASGYFASRSEIFRQALREYLQRIEWTERVGDEEYFGALTYVFQHERAEPELVKVQHEFTDVIISTTHIHVSPEKCLEVLLLQGPGKRIAELAKRIRGVRGVEQAKLTVVSSEGE", "output": "Transcriptional regulator."}]}
+{"id": "function_valid_3859", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGAMIVREVFEIAEKIKNMEIRGAGEIARAVAEALKIQAEKSKAKTSHELWKELKEASKILYNTRPTAVSLPNALRYVMYRGKIAYTSNADLESLRYTIINAAKEFIYNSEKAIERIGEIGAKRIEDGDVIMTHCHSKAAISVMKTAFDQGKDIKVIVTETRPRWQGKITAKELASYGIPVIYIVDGAARHYMKMTDKVVMGADSITANGAVINQIGTALIALTAKEHRVWVMIAAETYKFHPETMLGQLVEIEMRDPTEVVPKEELETWPKNIEVLNPAFDVTPPEYIDVIITEKGVIPPYAAIDILKEEFGWAFKYREPWED", "output": "Catalyzes the isomerization of ribose 1,5-bisphosphate (R15P) to ribulose 1,5-bisphosphate (RuBP), the CO(2) acceptor and substrate for RubisCO. Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and RubisCO."}]}
+{"id": "function_valid_3860", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEQKLGNLVKKNVVNSVFQGRSLLAEKDFTPMELEYLIDFALHLKALKKLGISHRYLEGKNIALLFEKTSTRTRSAFTTASIDLGAHPEFLGSNDIQLGKKESVEDTARVLGSMFDGIEFRGFKQSVVDDLARYSGVPVWNGLTDEWHPTQMLADFMTIKENFGHIKNINLSYMGDGRNNTANSLLITGSMLGANIRIVSPKELQPSEKTTELAKKFAEKSGSRFLITDNIDEGVSKTNVLYTDVWVSMGESDWEDRVKLLKPYQVNMETIRKTSTPDDQLIFMHCLPAFHDINTDYGHEIFEKYGIKEMEVTDEVFRSIYARQFEEAENRMHSIKAIMAATLGNLFIPHV", "output": "Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline."}]}
+{"id": "function_valid_3861", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDKKAIFDSVSNMEEQIGELYQQLGDLKTNLGEMLEENNRLNLENEHLRRRLSLTDEATPEPKAETEAEHGVMAPNRKEAMQQMIELGEGYDNLVQLYKEGFHVCNVHFGSPRGNDEDCLFCLSLLNKK", "output": "Involved in initiation control of chromosome replication."}]}
+{"id": "function_valid_3862", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MELTTRTIAARKHIALVSHDHCKKSLLAWVMENRDLLAQHELYATGTTGNLVQKATGIDVHCLLSGPMGGDQEVGALISEKKIDILIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNRSTADFLIGSTLFSSEVTIAIPDYDRYMQQRLDLK", "output": "Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate."}]}
+{"id": "function_valid_3863", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSSEHIQNKLALLPDQPGCYLMKDRQGTIIYVGKAKVLKNRVRSYFSGTHDSKTQRLVQEIVDFEYIVTSSNVEALLLEINLIKKHDPRFNIRLKDDKTYPFIKITNERHPRLIITRQVKKDKGKYFGPYPNVYAANEVKRILDRLYPLRKCSTLPNKVCLYYHLGQCLAPCVFDVEASKYKEMQDEIVAFLNGGYKTVKNDLMKKMQEAAENMEFEKAGEFRDQINAIETTMEKQKMTMNDFVDRDVFGYAIDKGWMCVQVFFIRQGKLIERDVSQFPFYNDADEDFLTFIGQFYQKANHIPPKEIYLPDDVDSEAVQAVVPDTKIIVPQRGNKKELVKLAYKNAKIALNEKFMLLERNEERTVGAVERLGEAMGIPTPSRVEAFDNSNIHGTDPVSAMVTFLDGKPSKNDYRKYKIKTVEGPDDYATMREVIRRRYWRVLKEGLPMPDLILIDGGKGQIDSAKDVLTNELGLDIPVAGLAKDDKHRTSQLLFGDPLEIVPLERNSQEFYLLQRMQDEVHRFAITFHRQLRSKTGFQSILDGIPGVGPGRKKKLLKHFGSMKKLKEASVEEIKEAGVPLNVAEEVHKHITAFNEKAKNTEQK", "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision."}]}
+{"id": "function_valid_3864", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDYKVKDLSLAEQGKKQIEWAEIHMPALMEIRKQFEKEKPLQGLRISAVLHVTKETAVLVKTLKIGGATVALAGSNPLSTQDDVAAALVEEGIRVFAWRGETEKDYYDNIKEILKYEPQIIMDDGGDLHAYVHENMPQLKLFGGTEETTTGVIRLKAMEEQGVLRYPVIAVNNAFTKYLFDNRIGTGQSTIDGILRATNILIAGKVAVVAGYGWVGRGIAQRLRGMGARVIVVEVSPLRALEAVMDGFDVMPMSKAAELGEIFITATGNINVIRKEHILKMKDGAILANSGHFNVEIDVKGLKEMAKSSRLIRPNLEEYELPNGKRIYLLAEGRLVNLAAAEGHPSEVMDLSFSNQALSVKYIYENRGKLENKVYNVPQEIDETVAKLKLNGMGIEIEPMTQEQIEYMKQWRYGT", "output": "May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine."}]}
+{"id": "function_valid_3865", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAASAGPEIERLIALLSKLPGLGPRSGRRAALALLKKRDTLLAPLATAMAEAQAKVRTCGTCGSLDVTDPCAVCADGSRDGRLLCVVEEVGSVWAMERGGSFKGRYHVLGGLLSALDGIGPEALRIGELVGRVADGSVAEVILALPATVDGQTTAHYIADRLAKTNVPVTMLARGVPVGGDLDWLDDGTIAQALRARRPA", "output": "May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO."}]}
+{"id": "function_valid_3866", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSTRAGRRVAISAGSLAVLLGALDTYVVVTIMRDIMHDVGIPVNQMQRITWIVTMYLLGYIAAMPLLSRASDRFGRKLLLQVSLAGFAIGSVMTALAGQFGDFHMLIAGRTIQGVASGALLPITLALGADLWAQRNRAGVLGGIGAAQELGSVLGPLYGIFIVWLFSDWRYVFWINIPLTAIAMLMIQVSLSAHDRGDELEKVDVVGGVLLAIALGLVVIGLYNPQPDSKQVLPSYGVPVLVGGIVATVAFAVWERCARTRLIDPAGVHIRPFLSALGASVAAGAALMVTLVNVELFGQGVLGMDQTQAAGLLVWFLIALPIGAVLGGWGATKAGDRTMTFVGLLITAGGYWLISHWPVDLLNYRRSIFGLFSVPTMYADLLVAGLGLGLVIGPLSSATLRVVPTAQHGIASAAVVVARMTGMLIGVAALTAWGLYRFNQILAGLSTAVPPDATLIERAAAVADQAKRAYTMMYSDIFMITAIVCVIGALLGLLISSRKEHASEPKVPE", "output": "In association with lipoprotein LprG probably transports triacylglycerides (TAG) across the inner cell membrane into the periplasm; TAG probably regulates lipid metabolism and growth regulation. May be an efflux transporter and involved in maintaining correct cell wall permeability. Probably required with LprG for normal surface localization of lipoarabinomannan (LAM)."}]}
+{"id": "function_valid_3867", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNNLNSVFDYEDIQLIPNKCVINSRLEADTSVKLGNFTFKLPVVPANMQTIIDDKIAEMLAKEGYFYIMHRFEAENRAAFIKKMHQQGLIASISVGVKADEHAFIREISADALIPEFITIDIAHGHADSVIKTIQLIKRLMPQTFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITKVKTGFGTGGWQLAAVKWCAKAASKPVIADGGIRTHGDIAKSIRMGATMVMVGSLFAAHEESPGQTVERDGQLFKEYFGSASEYQKGEHKNVEGKKILLPHKGSLKDTLKEMEEDLQSSISYAGGRDLSALTKVDYVVVKNSIWNGDAI", "output": "Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides."}]}
+{"id": "function_valid_3868", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEELQGYLEKDRSRQQHFLYPLLFKEYIYTFVHDRGLNSSVFYESTEIFGYDNKSSSVLVKRSIIRMYQQNYLIYSVNDSNQNRFVGHNNYFYFHFYSQMILEGFAVIVEIPFLLRLVSSLEEKKIPKSQNLNLRSIHSTFPFLEDKLSHLNYVSDILIPYPIHLKILVQILQFWIQDVPSLHLLRFFLHEYHNWNSLITPNNSIFLFSKENKRVFRFPYNSYVSECEFVLVFLRKQSSYLRVTSSGAFLERTHFYGKIEHRIVVRRNYFQKTLWFFKDPFMHYVRYQGKAILVSKGTHLLMKKWKCYLVNFWQYYFHFWSQPYRIHINQLSNCSFYFLGYLSSVLINPSAVRNQMLENSFLIDTVIKKFDTRVPVITLIGSLSKAKFCTVLGHPISKPIWTDLSDCDINDRFGRICRNLSHYHSGSSKKQSLYRIKYILRFSCAXTLARKHKSTVRAFLQRLGSGLLEEFFMKEEQVVSLIFPKTTSFSLHESHIERIWYLDIIHINDLVNYS", "output": "Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns."}]}
+{"id": "function_valid_3869", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MMTRMELRPLEIGFSKALTEVAPVTCQCECWDHNLCSSQASEMDLIYQSQDTHSCASKQDAVFQLLSETKIPVPNRYRKISHRLSTLSNKKTLKSQLDRFLSSSKKLHNDDVNRGDYCFLLSTPVECSASTNSHSYDCLWNFSCNSFPEYSSYSASETSSVASYSYYSGPNPATPSSSSCNLVNANSLDIYLNINNLKKSKSVPRLRGQFMEPVEHNHPLSKSLEEQSSFLEQSKDASSNLTACNRSGSSLSSNFYSSRLSKKTSLASLNKSRASLQHKIMSLSRNIIRRVFHKPEVHLDPSASILNLSSSHGESNLTNGLLCQNFKLFQDDWLMEDCAPDANFTLYTPLQPWEKRSVKPEIRRPRLNPNFFRVFVLEAQMRRAGKLSANTAGRAQLIYLPKPAVTFSTSPLHVEL", "output": "May have a role in meiosis and sporulation."}]}
+{"id": "function_valid_3870", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKNDTLNDVINSIKNASRLGKREIIAEPAAKLIGKVLKVMQDYNYIKSFEVIDESRGGKFKIVLNTTINNCGVIKPRFPVKNENLEKYEARYLPAEDFGILILTTTKGVMSNIEARKLGIGGKLLAYVY", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit."}]}
+{"id": "function_valid_3871", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MNIKPLPDNGDLVVVKITEVKNFGANGVLEEYPGVEGYIHISEVATGWVKHIRSYLREGQRVVCKVIGVNPERKVVDLSLKRVNQHQSREKIAEWKNEQKADKLFEIVCSRLNRNPEECKEQFGRRLVELFGTLFAAFESAAQSNGEWLPEMNGDWKNVFVEIAKENITIPEVSVSGYFEVYSLASDGVERIKEVLTIPEDTGKVELEYVGAPRYRIVVKDKDYKKAEEILKKVVQIVNEKAKKLQVEVEFNKQ", "output": "eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA."}]}
+{"id": "function_valid_3872", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSNQDSGNPAAKPPKGKTAARRKARSLAVQALYSWQIAGQPLHEIEAQFRTDNDFSEVDGAYFHEILHGVPRQKSELDSTFEPCLDRPLAEIDPVELAILRLSTYELRNRIDVPYKVVINEGIELAKTFGATDGHKFVNGVLDKLAPRLRAAELRGGKR", "output": "Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons."}]}
+{"id": "function_valid_3873", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRALRFSAGSWRCVFAWMLLLVGLAAQGAELSELERLRIAQVFPAVERIGDPEGDYGVRRLSKGEETLGYAFQTLSVTDIPAYSGKPINLQVILDPQAVIRDAYVLEHHEPILLIGIPEEKLHAFSARYDGVRADQRVVVGRSSDPQAVTVDAVSGATVTVMVVNEIVMRAAHTVAVALGLIEDRGNVRPKPAQVRQQPAATASWSELLGNGAIRRLQLSRGQIDDAFKGSEAEGIGEADAAHRDEPFIDLYSALLNPPAVGRSLLGDNQYRELMASLKPGEYAFVVLGDGEYSFKGSGYVRGGIFDRVQLRQFGDIISFRDLDYQRLSDVYAEGMPEFREMAIFVARASQRFDPGSPWTLELLVRRQTGPVAGVFTSFELACQTPEEYLERPQPTAEELAALEEAARPLWLRVWYQKSFQVGVLCTALVLLLAILFLQDRLVRRPRLMQRLRTGYLAFTLVYLGWYSLGQLSVVNVLTFVHALFEGFRWELFLSDPLLFILWTFTAASLLLWGRGVFCGWLCPFGALQELLNELARKLRVPQFQVPFAVHERLWAIKYIILLVLFGLSLESLALAEQAAEVEPFKTAITLGFDRQWWFVAYAVALLVVNLFTRKVYCRYLCPLGAALAIPAKARLFDWLKRRAECGRPCQLCARECEIQAIHPDGRIEANECHYCLDCQMTYHDQDKCPPLVNKRKKRAKSAPADNARIPAENL", "output": "Transcriptional activator of the nitrous-oxide reductase gene NosZ."}]}
+{"id": "function_valid_3874", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTAITISDQEYRDFCRFLESQCGIVLGDSKQYLVRSRLSPLVTKFKLSSLSDLLRDVVTGRNRDLRVAAVDAMTTNETLWFRDSYPFTVLADKLLPEMAANKRPIKIWSAASSSGQEPYSMAMTILEVQQKRPGLLPSVSITATDISASMLDMCRAGIYDNLALGRGLSPERRRVFFEDAGDGRMKVKDNVKRLVNFRPQNLMESYSLLGKFDIIFCRNVLIYFSPDMKSKVLNQMAASLNPGGYLLLGASESLTGLTDKFEMVRCNPGIIYKLK", "output": "Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP."}]}
+{"id": "function_valid_3875", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTDTPPENEEQHESNVQNENEVEHLQQEIVTLKTELKEKNDKYLMALAESENSRKRLQKERQELMQYALENTLIDFLNPIESMEKALGFATQMSDDVKNWALGFNMILNQFKQIFEEKGIIEYSSIGQKFNPFLHEAVQTEETSEVPEGTILEEFAKGYKIGERPIRVAKVKVAKAPTPKENKE", "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding."}]}
+{"id": "function_valid_3876", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MATATLPATVGVIGLWDGTTDGKEGFMDYATGDTNVKQPKEYEIEVHDIRKLDPQPTLLNNGYELVDIPTVVTEEQFSESGKSEKGKAYIKDVYFAECKRIIQEVAGGVDTIIPVSFRMREQKGEKESTTKKLGNIESRYAPRPVAHLDRDTPTAITVLEETVGKEKAQELLSKHKRNPATMWPLCFLNHDRIPTWNYDTHVGHVWSLNDPRVSDRGEKTYDCVVKYDERYDYHYVSDLKPEECLVFCSFDSIPKYAMPHSAFWDNNVPADAPNRRSIEVRSLVFF", "output": "Oxidoreductase; part of the gene cluster that mediates the biosynthesis of squalestatin S1 (SQS1, also known as zaragozic acid A), a heavily oxidized fungal polyketide that offers potent cholesterol lowering activity by targeting squalene synthase (SS) . SQS1 is composed of a 2,8-dioxobicyclic[3.2.1]octane-3,4,5-tricarboxyclic acid core that is connected to two lipophilic polyketide arms . These initial steps feature the priming of an unusual benzoic acid starter unit onto the highly reducing polyketide synthase clz14, followed by oxaloacetate extension and product release to generate a tricarboxylic acid containing product . The phenylalanine ammonia lyase (PAL) clz10 and the acyl-CoA ligase clz12 are involved in transforming phenylalanine into benzoyl-CoA . The citrate synthase-like protein clz17 is involved in connecting the C-alpha-carbons of the hexaketide chain and oxaloacetate to afford the tricarboxylic acid unit . The potential hydrolytic enzymes, clz11 and clz13, are in close proximity to pks2 and may participate in product release . On the other side, the tetraketide arm is synthesized by a the squalestatin tetraketide synthase clz2 and enzymatically esterified to the core in the last biosynthetic step, by the acetyltransferase clz6 (By similarity). The biosynthesis of the tetraketide must involve 3 rounds of chain extension (By similarity). After the first and second rounds methyl-transfer occurs, and in all rounds of extension the ketoreductase and dehydratase are active (By similarity). The enoyl reductase and C-MeT of clz2 are not active in the final round of extension (By similarity). The acetyltransferase clz6 appears to have a broad substrate selectivity for its acyl CoA substrate, allowing the in vitro synthesis of novel squalestatins (By similarity). The biosynthesis of SQS1 requires several oxidative steps likely performed by oxidoreductases clz3, clz15 and clz16 (Probable). Finally, in support of the identification of the cluster as being responsible for SQS1 production, the cluster contains a gene encoding a putative squalene synthase (SS) clz20, suggesting a likely mechanism for self-resistance (Probable)."}]}
+{"id": "function_valid_3877", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MADFAQLEVYIGDLSTAITSLITQCQRNGHATGSPSENLSRLFGLEAPTEAHRARESALVILTKLQIMLAGPTDLLQQMTIQTQLLACIRWLGEFQVPACIPLDGSALMKDVSELIDVPENQLGRIVRMAATCGFLREPEPGHITHSALSASFVTNPSYLDAAMFLAETAAPAALDMVAATKQRLGSSEPASQNVVFDQGFFSAANKTQLRRLQRQWQAYLRHGMAHLCDITTDFLTCLEPLRMGNASIVEVGARSAERAMALVDQYPTLHFTVQLSPASTLSSASKNGTAASKVRHPRIRVQHRVPGTPQPIQDAMVYIINFPVPEPGVSYNSPVAQISAELRAHLAPLRMNRSATIVLTAPSLPERGNVAAVGVARIRDLSLLQLANEQEVEMSDLLSLLNGVGDGEGRLVLVNEMRSAGNHGAVALEVKYQSYTDR", "output": "Transcriptional coactivator; part of the gene cluster that mediates the biosynthesis of agnestins, dihydroxy-xanthone metabolites."}]}
+{"id": "function_valid_3878", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEDFIYYNGKKYRKGYTTGTCAAAAAKACVEMILTQEEVSAVQVTTTGGTILEIPVAHQQFSKKRATAAVQKDGGDDIDATHGMWIFVDVELTNSTEVVLDGGVGIGRATQKGISVAVGEAAINPAPRKNILEAVRKSLGEHRGANILVYAPEGEERAKRTMNSNLGIIGGISILGTTGIVTPMSDEGWKKSLSMELEMKRNQGLEQIILVPGNYGDDFVQHTLGFSSNNIVSMSNFVGYMLKETQRLAFKKVLMVGHFGKLVKVSAGIFTTYSKDADARAEILVANLALLGAPLSLLQEVEKCNTTEAAGELIEEAGYTHVYEVIAQKIKARSERFLKFTKPSVEIDVVTFSTERGLLATTKDIDVLREEWQ", "output": "Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A."}]}
+{"id": "function_valid_3879", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MMHDDPNEAGLPPHNDAIPDETAEGADEVNPLHHRRIRSFVTRAGRVSTGQRRALDEFGPRFVVPYAPEMPDWDAIFGRSAPRILEIGFGMGASTAEIAAHRPSDDFLGVEVHEPGVGALLKLIGEQGLSNIRIIQHDAVEVLEHMIAPASLDGVHIFFPDPWHKARHHKRRLIQPPLVAHLASRLKPGAYLHCATDWQNYAEQMLEVLGAEPTLENTAADYAPRPDYRPVTKFERRGLRLGHGVWDLVFRKRAD", "output": "Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA."}]}
+{"id": "function_valid_3880", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAKKIDAYIKLQVKSGSANPSPPVGPALGQKGVNIMEFCKAFNARTEKMEKGMPIPVVITVYSDRSFTFETKTPPASYLLKTAAGLKSGSPRPNTQKVGTIARAKIQEIAELKAADMTGADVEAMTRSIEGTARSMGLVVEG", "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors."}]}
+{"id": "function_valid_3881", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIAQLKGSLAAKHPDHVVMDVHGVGYRVFISLATYNELPTVGEACLLYTVTHVREDAFLLYGFHSESQRKVFNLLTSVNGIGTKLALAALSSHTPEALLTALSREDLTLLCTIPGVGKKTAQRMAMELKDKLGALPMAAPTTAIGAATMAANPAGLREEVASALLNLGYKPPQVDAALAKLFSAGEITDISVALKGALKLLAPA", "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."}]}
+{"id": "function_valid_3882", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MALTAEQKKEILGTYGLHDTDTGSPEAQVALLTKRIADLTEHLKVHKHDHHSRRGLLLLVGRRRRLLKYVAQIDVERYRSLVERLGLRR", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.; "}]}
+{"id": "function_valid_3883", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKFSQRTLLKLKNKNKKLRPNKYKKLKRETLRGRIKGTVERPRLSVYRSNENIYAQIIDDTNSKTLISCSTLDRSIKLVISTGRTCDASRLMGEKLAKLSLKKNITKIVFDRGPYLYHGRIKAVADGARAGGLQF", "output": "Binds 5S rRNA, forms part of the central protuberance of the 50S subunit."}]}
+{"id": "function_valid_3884", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAKKITGYIKLQVPAGKANPAPPIGPALGQHGVNIMEFCKAFNAKTQADEGTITPVVITVYADRSFTFITKTPPVPVLIKKAAGIASGSAVPNKTKVGKLTKAQVEEIAKTKMPDLNAASLEAAMRTVEGTARSMGVDIV", "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors."}]}
+{"id": "function_valid_3885", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSNQNIRIKLKAFDHRLIDKSALEIVETAKRTGASVRGPIPLPTKKERFTVLTSPHVNKKARDQYELRTYVRLMDVISPTDKTVDALMKLDLAAGVDVAIKLN", "output": "Involved in the binding of tRNA to the ribosomes."}]}
+{"id": "function_valid_3886", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDQEPIPSSLEDNPQFKEETSLQKFRRRFKEEPLIPLGCAATSYALYRAYRSMKAGDSVEMNKMFRARIYAQFFTLIAVVAGGMYFKTERQQRREFEKMVEQRKAQEKRDAWLRELEVRDKEDKDWRERHAAMEAAAKEAGKRKSVPEQDAARSAIEPADEKSIGVLAAVRELLARQN", "output": "Cytochrome c oxidase subunit which plays a role in assembly of respiratory supercomplexes."}]}
+{"id": "function_valid_3887", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPLIMEDGINVDDLFGEPGSLELGLSPPSNAPIKGLPQRLDEMRLVGCCQKIAWSRLGCVAYITPDGMRVNVRHLQCRPSDGKWVLSEDTPLLPVTEAHGGHPLVHLCWNETGAELAVADSSGRVSIYSISIALNSIAGHRQATSDPDDDGAQIVGMMWLNVNRVVHAFHQAAKVQGRWAYSPFRRRPIGPFHPVNKAGLVCVTRSGTIRLLYQNPDSRWAEISTELKNTGYSDRLLTHAALVSTQGGVLVATHSACQKLCLYRVQIAWNPTQYDPGQQKPPAPWPVPSFRFLHCKVESLCDVIGTNRNPGDNQGLPSFTNSVYGLTRLDIILPALDNPAGSTSTPWIVAVYSSPLHATPDHPQQQSPASVIVRWQLDTGAVTLHPKFDEVGSKKSSAQMKPKLELRRLEDIYSDRYAISIDQIEYGNVLAITYEDGSIVFHDPKTMAVFNGVDDTNTVTSLAQAGFHYPPEASGLHMAFSPNACAAVMLDAEGQTQLRLTEHTYGAEGGLHDENKYSAAIAALTLAFCRGCGSDVNIDDVILILVRQLSSEAQINFINEVYRALSVNCNFTMEQDKLMNHIYIPRCLSLQAALGFKDKYTPRSSPSAIPWAILQLRHASVLYAFFFQYNKGAPTESHDPDVLRMVLGNTKWALEFSFYVSNELFDLADEFESMASDQEAFTQKLKSTTSLPLIILLSSMSRAFLRFICRGLRGIHAGYATAAPLTGDARVYYAEIYQTLENSPVRIDAYEKFLAGVDSAVRHAYHSAGFGDAERPGPEKELLVNARVPPVLVSAVATILRQTVPALKSEIDRITIYMGNYSWLGLAHDRRTEMYRRTRDVDIIKKIPLRSLGPYTEVDAAPSGKTNAQGPPQQPQPQQQRRRRCVRCCEISGDTHPPRSLLSFRMIAKLGLLRSCVCGGMWTLVEPEVSAPAADPPVSQATGRTPALMAIGLAGSS", "output": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity)."}]}
+{"id": "function_valid_3888", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTLACCKLDPHPQSPARQHTGPWLVWLHGLLGSGQDWLPVAELCGDYPSLLIDLPGHGNSVALTTTGFEDISRQISETLQANGIREYWLAGYSLGGRIAMYHACYGHKVGLQGLLVEGGNLGLESDELRKARFEQDCQWAQRFRHEPLPQVLADWYQQDVFADLDSQQREQLVAVRANNHGPAVADMLEATSLGHQPWLLPALQCLSVPYTYLCGERDHKFQQVAHQYKLPLRTLARAGHNAHRANPGAFAALVLSFLSQSSFLPLSSFLPPSR", "output": "Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)."}]}
+{"id": "function_valid_3889", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MATAASNPYSILSSSSLVHDSAIMQQGSPFRNPQKLLQSDYLQGVPSNGHPLGHHWVTSLSDANPWSTSLGSSPLDQQDIKPGREDLQLGAIIHHRSPHVTHHSPHTNHPNAWGASPAHNSSLTSNGQPINVYSQSGFTVSGMLDHGGLTPPPPSGTTQSLHPVLREPVDHGDLGSHHCQDHSDEETPTSDELEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQATICRFEALQLSFKNMCKLKPLLNKWLEEADSSTGSPTSIDKIAAQGRKRKKRTSIEVSVKGVLETHFLKCPKPAAQEISSLADSLQLEKEVVRVWFCNRRQKEKRMTPPGDPQQHEVYSHSVKTDTSCNEL", "output": "Transcriptional activator. Induces neural-specific gene expression to act as a key regulator of neural differentiation (By similarity)."}]}
+{"id": "function_valid_3890", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MATTNDIKNGTVLKLEGQLWNIIEFQHVKPGKGGAFVRTKMRNVMSGKVVDKTFNAGLKIETATVDRRDYQYLYQDGEDFVFMDTQDYDQITVSGATVGDATNFMLENQMVNIAIHEGTPLYIELPPSVVLEITYTEPGLQGDRSSAGTKPATVETGYEIQVPLFVEQGTKVKVDTRDGSYLGRVND", "output": "Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase."}]}
+{"id": "function_valid_3891", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSKNSKAYKEAAEKVDKTRLYSPLEAAKLAKETSSKKQDATVEVAIRLGVDPRKADQMVRGTVNLPHGTGKTARVAVFAVGDKAEQAEAAGADIVGSDDLIEKIQGGFLDFDAAIATPDQMAKVGRIARILGPRGLMPNPKTGTVTPDVAKAVSDIKGGKINFRVDKQANLHFVIGKASFDESKLAENYGAALDEVLRAKPSSSKGRYLKKVVVSTTTGPGIPVDPSITRNFTEE", "output": "Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.; "}]}
+{"id": "function_valid_3892", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPRKGPAPKRPLVNDPVYGSQLVTQLVNKVLLDGKKSLAERIVYGALEQAREKTGTDPVVTLKRAMDNVKPSLEVRSRRVGGATYQVPVEVRPDRSVTLALRWLVSFSKARREKTMVERLANEILDASNGLGAAVKRREDTHKMAEANRAFAHYRW", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."}]}
+{"id": "function_valid_3893", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPSPSSHTELPDSSSLRHILAVAHSPLAEPGVARTLATELGLDWLGVVAPKQVRDYGLLLFMDEHGLALQQTGKGAPGPVRAEFVSGKMGYRREHGGGAGQLVARAVGMQKTRAPLQVLDATAGLGQDAFVLASLGCQMTLFERNPIIHALLADGLYRASLNEACAPIVARMTLHSGNSLDWMNQAGPEAVDVVYLDPMFPHRDKSALVKKEMQVFRQVVGDDDDASQLLEAALGCARYRVVVKRPRKAPAIAGPEPAARVEGKSSRYDIYPIRALPA", "output": "Specifically methylates the guanosine in position 1516 of 16S rRNA."}]}
+{"id": "function_valid_3894", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSGKNNIISQLEAEQMTKEIPAFAPGDTVVVQVRVTEGNRERLQAFEGVVIGKRNRGMNSSFTVRKISYGVGVERTFQTYSKLIDSVSVKRRGDVRQAKLYYLRDLSGKAARIKEKLN", "output": "This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site."}]}
+{"id": "function_valid_3895", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MARLNVKPTRMELSNLKNRLKTATRGHKLLKDKRDELMRRFVDLIRENNELRQTIEKELAANMKEFVLAKASENSLMVEELFAVPVHEVTLWIDIENIMSVNVPKFHVQSNTAREQEQGEFAYSYLSSNSEMDNTIQKTKELLEKLLRLAEVEKTCQLMADDIEKTRRRVNGLEYAIIPQLEETIHYIELKLEEAERASLVRIMKITS", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane."}]}
+{"id": "function_valid_3896", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAIADNKKARFNYTIEEQFEAGMVLEGWEVKAIRAGQVQLTDGYVVVKDGELFLIGCRINPLRTASTHVHPQADRTKKLLMKKDEIRRLVGKVEQKGYTLVPLNLHYKGGRVKADIALAKGKDLHDKRETEKKRDWEREKGQLMRHKISSPRKDT", "output": "Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation."}]}
+{"id": "function_valid_3897", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MVNDTVANMITSIRNANVIEATTVRIPATNTTKDVGKILLQEGFITNLREHKENTRSFLILTLKYRGRKKKPYITNLKRISKPGLRIYSNHREIPKVLGGMGIVILSTSSGIVTDREARQKQIGGEILCYVW", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit."}]}
+{"id": "function_valid_3898", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAGKSGEEKMKEMEAEMALFEQEVLGAPVAPSPVDPVPLSIQAVPIIRPVIATNTYSQVQQSLQARAAAAASVVGPNFVSPVTFVGPAIPPPRPPVMRPSFIPHALQRPIEPHGAMTRPSFIPHVLQHRAPGPRHPGMPPLQPLMAHHMHGPPPPLMRHIPPPPLGMRPGPPPAPMGPLPPPPRPMVQSAPKINPTVIQAAPTVYTAPPVRKPEEEIVEPPIIPEEKESLSYEETVIGPSMPEIEPVQPEVVLEPVQEDKKKAKPEKLKRCIRTAAGTSWEDQSLLEWEPDDFRIFCGDLGNEVNDDILARAFSRYPSFLRAKVIRDKRTGKTKGYGFVSFKDPNDYVRATREMNGKYVGSRPIKLRKSQWKDRNIDVVRKKQREKKKLGLR", "output": "May bind RNA."}]}
+{"id": "function_valid_3899", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIGLVGRKVGMTRVFTEDGVSIPVTVIEIEANRVTQVKTLENDGYSAIQVTTGSKKANRVTKPEAGHFVKAGVEAGRGLWEFRTEGEEFTLGQEINVDIFTDVKKVDVTGTSKGKGFQGGVKRWNFRTQDATHGNSLSHRVLGSIGQNQTPGRVFKGKKMAGHLGAERVTVQSLEVVRVDAERKLLLVKGAVPGATNSDVIVKPAVKA", "output": "One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit."}]}
+{"id": "function_valid_3900", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGKIIGIDLGTTNSCVAIMEGNQVKVIENSEGARTTPSIIAYMDDNEVLVGAPAKRQSVTNPKNTLFAVKRLIGRRFEEKEVQKDIGLMPYAIIKADNGDAWVEAHGEKLAPPQVSAEVLRKMKKTAEDYLGEPVTEAVITVPAYFNDSQRQATKDAGRIAGLEVKRIINEPTAAALAFGLDKAEKGDRKIAVYDLGGGTFDVSIIEIADVDGEMQFEVLSTNGDTFLGGEDFDQRIIDYIIGEFKKEQGVDLSKDVLALQRLKEAAEKAKIELSSSQQTEINLPYITADASGPKHLNLKVTRAKLEALVEDLVERTIEPCRTAIKDAGVKVSDIDDVILVGGQTRMPKVQEKVKEFFGKEPRRDVNPDEAVAVGAAIQGQVLSGDRKDVLLLDVTPLSLGIETLGGVMTKMINKNTTIPTKHAQVYSTADDNQGAVTIKVFQGEREMAAGNKLLGEFNLEGIPPAPRGVPQIEVTFDIDANGILHVGAKDKATGKENKITIKANSGLSEAEIEKMVKDAEANAAEDHKLRELAESRNQGDALVHSTKKALTEYGDKLEAGEKEKIEAALKELEDVLKNASSDKAAIDAKVEAVATASQKLGEKMYADMQAQQAGAAGAAGAAAEGASAQGGAQPADDVVDADFKEVKKD", "output": "Acts as a chaperone."}]}
+{"id": "function_valid_3901", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKPSDWLILQKKVRFGDCDSAGVIHFHNLLKWSHEAWEESIEIYGIPCNDIFPDFSIRKSQIIFPIVNCEANFNAPIKIGDLLKVKIAPHKINTHLFQVNSFFIKNGNKVAEGKIIHCSLDVDSRNKIEIPDQLERWIEASNVSTNLKEC", "output": "Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis."}]}
+{"id": "function_valid_3902", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MHLARFPRRFIAHLPTPLERLDRLSAELGGPEIWIKRDDCTGLSTGGNKTRKLEFLMAEAELQGAEIVMTQGATQSNHARQTAAFAAKLGMKCHILLEDRTGSNEANYNHNGNVLLDHLHGATTEKRPGGGDMNAEMEKLADEWRADGKKVYTIPGGGSNPTGALGYVNCAFELLAQANDGGLKIDHIVHATGSAGTQAGLITGLKAMNAQIPLLGIGVRAPKPKQEENVYNLACATAEKLGCPGVVAREDVVANTDYVGQGYGIPTESGMEAIKMFAELESILLDPVYSAKGAAGFIDLIRKGHFKKGERVVFLHTGGAAALFGYDGAFDFSSRWVG", "output": "Catalyzes the desulfonation and deamination of L-cysteate, yielding pyruvate, sulphite and ammonium. Involved in sulfolactate degradation."}]}
+{"id": "function_valid_3903", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSGASARDATFLAFDYGEKRIGVALGNALTRSARALVVIPNLNREHRFKAVGELLAEWRPDALVVGLPMHPDGTPHDMTQQAKRFGNQLNGRFGLPVTWVDERYSSVEAEAGLRERNVRGRARTDMLDAEAARVILQQYFDELSDHEHH", "output": "Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA."}]}
+{"id": "function_valid_3904", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAKFQGYLEFDGARQQSFLYPLFFREYIYVLAYDHGLNRLNRNRSIFLENSDYGKKYSSLIVKRLILRMYEQNRLIIPTKDLNQNPFLGHTNLVDYQMISILFAVIVEIPFSLRLGSSFEGKQLKKSYNLQSIHSIFPFLEDKLSHFNYVVDVLIPYPIHLEILVQTLRYRVKDPSSLHFFRFCLYEYCNWKNFDIKKKSILNPRFFLFLYNSHVCEYESIFFFLRKRSSHLRSTSYEVLFERILFYGKIQHFLKVFVNTFPAILGLLKDPFIHYVRYHGKCILATKDTPLLMNKWKYFFVNLWQCYFSVWFQSQKVNIKQLSKDNLEFLGYLSSLRLNPLVVRSQMLENAFLIDNVRIKLDSKIPISSIIGSLAKDKFCNVLGHPISKAAWTDSSDSDILNRFVRICRNISHYYSGSSKKKNLYRIKYILRLCCVKTLARKHKSTVRAFLKRLGSGLLEEFLTGEDQVLSLIFPRSYYASKRLYRVRIWYLDILYLNDLVNHE", "output": "Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns."}]}
+{"id": "function_valid_3905", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVERDNELKGTTFTISVLHISDGKPERIRQLLAAKVAQAPQFFNCAPLVINVERLADIPDFDQLKGLVESEDFVLVGITGARDEAMKTAAKAAGLAVMASGKSRKVEPLPLPEPTPSPVAEVKAAPAPLVPSKVHVGPVRSGQQLYAAGTSLVILGSVSQGAEVIADDSIHIYGALRGRAIAGAKGNTQARIYCQQLQAELLSIAGTFQLSDALPAGLIQQPVHVRLDNEQLRIDHIK", "output": "Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization."}]}
+{"id": "function_valid_3906", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIDKTAFIHPSSIVEEGAIIGAGVYIGPFCIVGSQVEIGAGTELKSHVVVNGITKIGCDNQIYQFASIGEANQDLKYAGEPTRVEVGDRNRIRESVTIHRGTTQGGGVTKVGCDNLLMVNTHVAHDCVIGNRCILANNAALGGHVEIDDYAIIGGMTAIHQFCVIGAHVMVGGCSGITQDVPPFVIAQGNHATPFGINIEGLKRRGFDKESLHAIRSAYKLLYRSGRTLDEVKPEIAELAEQYPVVKAFNDFFARSTRGIIR", "output": "Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell."}]}
+{"id": "function_valid_3907", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSQLDTTTPSGDYLMALDAGTGSVRAVIFDLNGNQIAAGQAEWLHLPVPDVPGSMEFDLTTNWQLTCQCIRQALHLAKLPASAIRAVAACSMREGIVLYDRSGTPIWACANVDARASREVSELKELHNNGFELEVYQCSGQTLALSAMPRLLWLAHYRPDIYRQAGTLTMISDWLANMLSGELAVDPSNAGTTGMLDLVTRNWQPNLLEMAGLRADILSPVKETGTLLGHVTAKAAQECGLLAGTPVVMGGGDVQLGCLGLGVVHAGQTAVLGGTFWQQVVNLPQPIIDPNMNTRINPHVIPGMVQAESISFFTGLTMRWFRDAFCAEEKLLAQRLGIDTYSLLEDMAARVPAGAYGVMPIFSDVMRFKSWYHAAPSFINLSLDPEKCNKATLFRALEENAAIVSACNLAQIAEFSGVKASSVVFAGGGAKGKLWSQILADVTGVPVKVPVVKEATALGCAIAAGVGVGLYEALDKTGERLVRWEREYIPNTEHKALYQAAKTNWQAVYTDQLGLVDCGLTTSLWKAPGL", "output": "Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position."}]}
+{"id": "function_valid_3908", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSNTESIIVSQTKTTSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLQMPALNRGFVALFLLLLMAFVIWFGKDLMVKVMSFLVFPFIASLILISLSLIPYWNSAVIDQVSMSDLSFTGHDGILVTVWLGISIMVFSFNFSPIVSSFVVSKREEYEGEFGKEFTEQKCSKIIGRASLLMVAVVMFFAFSCLFTLSPQNMAEAKAQNIPVLSYLANHFATMTGTKSTFATVLEYGASIIALVAIFKSFFGHYLGTLEGLNGLVLKFGYKGDKKKVSVGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASLLCLLPMFAIRKVPALAKFRGRTENLFVTAVGLLTILNIVYKLF", "output": "Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system)."}]}
+{"id": "function_valid_3909", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSSETLEFQAEARQLLQLMVHSIYSNKDVFLRELISNASDALDKLRLASLRDKDLDVDTADLHIAIEIDPDARTLTVRDNGIGMSRDEVVQVIGTIAKSGTAELLRTLRESADAETSQELIGQFGVGFYAAFMVADRVVLVTREAGATDGTRWESSGEGTYTIASATDAPQGTAVTLHLKPADSEDNLHDYATEWTVRQIVKRYSDFIAHPIRMAVEQPGTDGGESTTEVQTLNSMKALWARSRDEVEPAEYHEFYKHVSHDWADPLEVVHMRGEGTFEYEALLFLPTHAPLDLFSPQGRRGVQLYVKRVFIMDDCEALMPGYLRFVKGVVDAHDLSLNISRELLQQDRQIQVVRRRLVKKILATVKELKANQPEKYRTFWTEFGAVVKEGLIDDTENRDSLLEILSVASTHDPAEPTDLADYVTRMKDGQTDIYYATGENRSTIENSPHMEAFRAKGFEVLLLTDPVDEVWVERVGEYEGKTLRSVAKGQVDLDTEEERSAAEAERERQRTEYADLLTWLSSTLADQVREVRLSARLTTSPACVVGDAHDVTPTLEKMYRAMGHEVPQVKRILELNPTHPLVSGLRKAREQGVTEESLKETAELLYGMALLAEGGELADPSHFTRILAERLARTL", "output": "Molecular chaperone. Has ATPase activity."}]}
+{"id": "function_valid_3910", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MADPSSYRPAPGTIPESPGVYRFRDGTGRVIYVGKARNLRNRLNSYFADPVNLHQRTRQMVFTAESVDWISVATEVEALQQEFTEIKQYDPRFNVRYRDDKSYPYLAVTVSEEFPRLQVMRGAKRKGVRYFGPYSHAWAIRETLDLLLRVFPARTCSSGVFKRAGQVGRPCLLGYIDKCAAPCVGSVSAEEHRAIVEGFCDFMAGRTDLMVRRLEREMADASAELEFERAARLRDDLAALRRAMEKQTVVFGDGTDADVVAFADDPLEAAVQVFHVRDGRIRGQRGWVVEKTEELTIGDLVHHFCTQVYGGEQGEADVPRELLVPELPADVEALADWLSDHRGSRVTLRVPQRGDKRALLETVARNATDALARHKLKRAGDLTTRSKALDEIAETLGLQTAPLRIECYDISQIQGTDVVASMVVFEDGLPRKSEYRRFIIRGATDDLSAMSEVLRRRFARYLDARAETGEAGVESAGDPATPAGPASTGPGVPDEPRVGTLVDPTTGRPRKFAYPPQLVVVDGGAPQVAAAAQALAELGVDDVALCGLAKRLEEVWLPDDDFPAILPRTSEGLYLLQRVRDEAHRFAITFHRQRRSRRMTESALDRVPGLGEVRRKALLRHFGSLKRLSAASVEEITEVPGVGQRTAEAILAALGDSTQPDEPRT", "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision."}]}
+{"id": "function_valid_3911", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSRIGRKSIPVPTGVDVTIAGQTVTVKGPKGELSHTIAEPITIDRAEDGQLNVARPNDERKAKELHGLSRTLVANMIVGVTEGYRKSLEIAGTGYRVTAKGKDLEFALGFSHPVTVVAPEGITFSVEKPTLFHVAGINKQLVGEVAANIRKIRPPEPYKGKGVKYQGEVIRRKAGKAGKK", "output": "This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center."}]}
+{"id": "function_valid_3912", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MARIAGVDLPREKRIEIALTYIFGIGLSRSKQILRDTGVDPNKRVKDLTDDEVAKIRDYIDKNFKVEGELRAEIARNIKRLIDIRCYRGLRHLRGLPVRGQRTRTNARTRKGPRKTVGVMRKKS", "output": "Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites."}]}
+{"id": "function_valid_3913", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTQDEMKKAAGWAALKYVEEGSIVGVGTGSTVNHFIDALATMKDDIEGAVSSSEASTQKMKALGIPVYDLNSVDRLSVYVDGADEINDRMDMIKGGGAALTREKIVAAVAEKFICIVDNTKQVNILGEFPLPVEVIPMARSYVARQLVKLGGDPVYREGVVTDNGNVILDVYNLKILNPKELESQINEIVGVVTNGLFAKRGADVLLVGTPDGVKTFTAK", "output": "Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate."}]}
+{"id": "function_valid_3914", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPVLVSNLQGKVAVDEALTGLLTRAAQEVLKAEGYGEEAEVSLVFVDDAYIHGLNRQYRGVDAPTDVLSFAMQEGEPLAGGEEELILGDVVISLQAAERQAGEYGHSLQREAAYLAVHGVLHLLGYDHQGEEERKIMRRKEEEVLGRLNLTR", "output": "Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA."}]}
+{"id": "function_valid_3915", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRPIKLMGHERSLTQVKYNREGDLLFSVAKDNAASIWYSSNGERLGTLEGHQGVIWSIDVDPETLLCATGGGDLAVKLWTVENGQCVYTWNSPSPVRRVSFSPDGKKLLVIADQVMGHIGTISVYDINRDTASLTNQAETASLVIETEQNGSKATVAGWSEDGRFIIAGHDNGYVSKYDAHTGELLKSLQAHGIHNEEKNVSVTDIQFAPEDRSYFITSSKDKCAVLTDVDTFEILKVYKADAPMNTAAITPLKDFVILGGGQEARNVTTTAESQGKFEARFYHKIFEEEIGRVKGHFGPLNTVAVHPDGTGYSSGGEDGFIRVHTFDKSYKDFLFDAERTEKAAAAGLD", "output": "Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation."}]}
+{"id": "function_valid_3916", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSRIGKSPIPIPDKVSVSLDGLAVTVKGPKGELKRTLPDGVTVNQVDNTIVVAPTSEKRQSRERHGLCRTLVANMIEGVSKGYSKKLEIVGVGSRAQVKGKTLVVSAGYSHPVEMLAPEGITFAVENNTNVTVSGTDKELVGNEAAKIRAIRPPEPYKGKGIKYAGERILRKAGKSGKK", "output": "This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center."}]}
+{"id": "function_valid_3917", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAKRVQVVLSEDILSLGKDGDLVEVAPGYARNFLLPHGKALPVTPAVLKQVEHRRAKEAERLAALKADAVAFRTALDTIGRFTVKKQTGGDDVLFGTVTNVDVAEAIESATKKLVDKRDITVPEVHRTGNYKVQVKLHPEVVAEINLEVVSH", "output": "Binds to the 23S rRNA."}]}
+{"id": "function_valid_3918", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEQQHIEVVGKLGSTYGIRGWLRIYSSTEQAESIFDYQPWFLKIKGEWQSIELENWRYHNHEIIVKLKGVDDREAAQILANVEIGVDLSVFPELEEGDYYWHDLIGCTVVNLEGYTMGTVTEMMETGSNDVLVVKANTKDAFGKQERLIPFLYEQVVKRVDLTTKTIEVDWDAGF", "output": "An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes."}]}
+{"id": "function_valid_3919", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKNMLLLSSSKYKNTGYLEHTLPWLQNFLADYRGKTIAFVPYAGVRRTFDEYEKTVQNALSYLEMNIVSVHHGKQHRDIIEQADVIAIGGGNTFCLLKQLYEHNLIDIIREKVNNSTPYFGWSAGANVVGASIMTTNDMPITYPPSFQALQLFPHQINPHFISGKMQGHNGESREERLAEFLLVNPTALVYALPEGSALHIQNEMATVLGENPILCFSENMECGTFDINTTFSY", "output": "Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids."}]}
+{"id": "function_valid_3920", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MASEHLEHKLALLPDKPGCYLMKNINDQIIYVGKAKNLKNRVRSYFKSSHTGKVAKMVSEVADFETIVTSTNKESFLLEITLIQKHQPYFNIKLKKGTGYPYIKITNERDPQIKIVSKIKKDGGYYFGPYPNVYAAEETMHFIQKVYPLRRCNGYQGRPCLYYHMGQCLGACFKEVPKSDYEEQIKKIKSFLSGNTATVKRQLTKKMQRAAENMEFERAAEIRDQLHYIEVTVEKQKIISNDKTPRDLFNFYMDKGWLSIQIFFIRQARLMKREKRLFPIVDTAVEEMTSFILQFYNRRNNILPHEILLPKGLPNKEISEILGVPVRTPVRGEKRDLLAMAHENAQLSLDEKFRLLEMDQSKTTGAMKEITDALGLPEGHRIEAFDHSHIQGADPVSAMVVFINGEPAKNFYRKYKLKTVINHADEAASTREVIRRRYSRLLKENKPMPDMIFMDGGEIQMDAAKDVLENELGLEIPVVGMVKNDKHQTADLLFGDDDHHINLNPRSQGFYLVQRIQDEVHRFAITFHRRVHTKHSLSSRLDEIKGVGPRTRTKLLKKYGSITKIAQASVDEIHSLGINRPTAQLIKVSLQKNAEVAKGSSHD", "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision."}]}
+{"id": "function_valid_3921", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSRVGRLPIAIPADVTVTVTPDNLVTVKGPKGELVKTMHKDISIAVENNEVIVTRHSEQKDHRALHGLTRALINNMVIGVKQGYQKTLDLVGVGYRAQLQGKKLVMNLGYSHPVEIEPIDGITFETPAATRVIVSGIDKEKVGFAAADIRKWRVPEPYKGKGIKYENEVIRRKEGKTGKK", "output": "This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center."}]}
+{"id": "function_valid_3922", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDIISLGWSSLLVVFTFSLSLVVWGRNGF", "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions."}]}
+{"id": "function_valid_3923", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAEKKRAQEQEKVQEDQKMQNEQNECEEVEKKLQECEEKYLRVHADFENTKKRLEREKIQAIEYSLEKFAQDLLPALDSLDMALAAVSHDNLNAEEAVKELKKGIELTIDQFIKAFNKNGIEVIEIEEGGEFNPHLHEAILQVDDAEKKAGQIVQVIQKGYKYKERILRPAKVSVAKGNE", "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding."}]}
+{"id": "function_valid_3924", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGSVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK", "output": "Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins."}]}
+{"id": "function_valid_3925", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MFQDNPLLAQLKQQLHSQTPRAEGVVKGTEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIVAVIHSEKERESAEPESLVEPFLTRFVGKVQKKDDRLAIVPDHPLLKDAIPCRAARGVEHDFKQGDWAVAEMRRHPLKGDRGFYAELTQFITFSDDHFVPWWVTLARHNLEKEAPDGVATEMLDEGLTRRDLTALDFVTIDSASTEDMDDALYAESTADGKLLLTVAIADPTAWIAEGSKLDNAAKVRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPVLACRMTLAADGTIEDNIEFFAATIESKAKLAYDDVSDWLEGRGSWQPDSEAIAQQITLLKDVCQRRSEWRQTHALVFKDRPDYRFVLGEKGEVLDIVAEPRRIANRIVEESMIAANICAARVLRDKLGFGVYNVHTGFDPANTEQLAALLKTHDVHVDPTEVLTLEGFCKLRRELDAQPTGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAIIKGETIARPQDEATVQMAERRRLNRMAERDVADWLYARFLNDKAGTDTRFAAEIIDVSRGGMRVRLVDNGAVAFIPAPFLHAVRDELVCSQENGTVQIKGEVVYKVTDVIDVTIAEVRMETRSIIARPAV", "output": "Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction."}]}
+{"id": "function_valid_3926", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSVTAERKAQIIKEFATAEGDTGSPEVQVAILTERINNLTEHFKDHKKDNHSRRGLLALVSSRRSLLDYLKKKDEARYTKLIGALGIRR", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.; "}]}
+{"id": "function_valid_3927", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MFAVIKTGGKQYRVAANDLIKVEKVAGEAGDIVEFAEVLMVGSTIGAPTVAGAIVTAEVVEQGRARKVIAFKKRRRQNSKRTRGHRQELTTIRISEILTDGAKPSKKAAEKKAPKAAPKKAAAKAESAE", "output": "This protein binds to 23S rRNA in the presence of protein L20."}]}
+{"id": "function_valid_3928", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MARVKTGVVRRRKHKKVLKLARGFYSGRRKHFRKAKEQLERSLVYAYRDRRRKKTDFRRLWIVRINAACRLNDLSYSRFINGLKKAGIELDRKILADLAMNDVAAFAKIAEAAKKAL", "output": "Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit."}]}
+{"id": "function_valid_3929", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSRGKKTVERVVELMKDPKHIRNIGIVAHIDHGKTTLSDNLLAGAGIISEELAGKQLFMDSDAEEQARGITIDASNVSMVHEVEGQDYLINMIDTPGHVDFGGDVTRAMRAVDGAVVLVDAVEGTMPQTETVLRQALKEQVRPVLFINKVDRLVNELKVDETEMQIRLGKVIDKVNKLIKGMNEDLYNNGWKLDASKGTVAFGSALYNWAVSVPYMKKGGVSFKDVFEKCRAGDMKYLAKNSPLYEVVLDMVVHHLPNPLEAQPRRVNVIWHGDHSTKEGKAMLACDPNGPATMMVTDISFDPHAGEVATGRLFSGTLRRGDGLYVMGSAKKENRLQQVGIFMGPKRVEVEEIVAGNIAAVTGLKDAIVGSTVTSLMEMSPFESLKHYSEPVMTVAVEAKNMKDLPKLVEVLRQVAKEDPTLGIAINEETGEHLISGMGELHLEIVTGRIKRDKGVEIVTSEPIVVYRETVTGKVEDVEGKSPNRHNRFYFTLEPLPEEIVNLIKAGEITMNQQAIERRDVLLKAGMDKDEAKNVKHIKGTNMLIDMTKGIQYLNETMELIIEGINEALAGGPLADEPVQNLKMTLTDVKLHEDAIHRGPAQVIPAVRGAIKGGMLIAGDSLLEPVQKIQISVPMDQMGAATSQIQGRRGQVFDMQSEGDTITVVGKAPVAELFGFAGDIRSATEGRAMWNTEFAGFELVPNNLVKDVVVAIRKRKGLKEQMPTPSDYLSV", "output": "Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome."}]}
+{"id": "function_valid_3930", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDSLTTLYKNHLDTLQERTRNVLARFNLDALLIHSGELFNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPSAFWTEEIDIIALPKADDIGGQLPAARGNIAYIGPVPERALKLDVPADKINPKGVIDYLHFYRAYKTDYELACMREAQKTAVNGHRAAHEAFLSGMSEFDINLAYLTATGHRDTDVPYSNIVALNEHAAVLHYTRLDHRAPSEMRSFLLDAGAEYNGYAADLTRTWAADGDSDFAALIKDVNEEQLALIGTMKAGVSYIDYHIQFHQRIAKLLRRHQIVTDISEEAMVEADITGPFMPHGIGHPLGLQVHDVAGFMQDDTGTHLAAPAKYPYLRCTRVLQPRMVLTIEPGIYFIESLLVPWREGPFSKHFNWQKIEALKPFGGIRIEDNVVIHEHGVENMTRDLKLA", "output": "Splits dipeptides with a prolyl residue in the C-terminal position."}]}
+{"id": "function_valid_3931", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIEIKKAKPTSPGRRHVVSVKNTELHTGKPFKGLVEVKKSKAGRNNTGRITVRHQGGGHKQHYRIVDFKRNKDDITAKVERIEYDPNRSANIALVLYADGERRYIVAPKGLKKDMSVISGEKVDIAVGNCMPLRNIPLGTVIHNIEMKPKKGAQMIRSAGTFAQLVGKDNAYAIIRLRSGEMRRVLLDCRAVIGVVSNSEHNLKSLGKAGAKRWRGIRPTVRGVAMNPVDHPHGGGEGRTSGGRHPVTPWGIPTKGYKTRRNKRSNKLIVQKRK", "output": "One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome."}]}
+{"id": "function_valid_3932", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRSTLKGALQPFTPLLLRFGGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEYETRFSELFFDYLHCIQSLAGATGTPEPALRRFELALLGHLGYGVNFTHCAGSGEPVDDTMTYRYREEKGFIASVVIDNKTFTGRQLKALNAREFPDADTLRAAKRFTRMALKPYLGGKPLKSRELFRQFMPKRTVKTHYE", "output": "Involved in DNA repair and RecF pathway recombination."}]}
+{"id": "function_valid_3933", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSSRVLTPDVVGIDALVHDHQTVLAKAEGGVVAVFANNAPAFYAVTPARLAELLALEEKLARPGSDVALDDQLYQEPQAAPVAVPMGKFAMYPDWQPDADFIRLAALWGVALREPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRASNGGLPKRDVNTVSEPDSQIPPGFRG", "output": "This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'."}]}
+{"id": "function_valid_3934", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDNRPIGFLDSGVGGLTVVRELMRQLPHEEVIYIGDSARAPYGPRPAEQIRDYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKEKLDIPVLGVILPGASAAIKSTHSGKIGVIGTPMTVTSDIYRKKIEALSPEMEVSSLACPKFVPLVESNELTSSVTKKVVYETLLPLAGKVDTLVLGCTHYPLLRSIIQNVMGPDVKLIDSGAECVRDISVLLNYFEINRSREEQTLRHRFYTTASAKSFAEIAEHWLGQKVSVEHIDL", "output": "Provides the (R)-glutamate required for cell wall biosynthesis."}]}
+{"id": "function_valid_3935", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDVTRLLLATLLVFLCFFTACSHPPPGEKLRDDRSLRSNSSVNLLDFPSVSIVALNKNSKQISRKEAEKKRSSKKEASMKKVARPRTPLSAPCVATRDSCKPPAPACCDPCASCQCRFFRSACSCRVLSLNC", "output": "Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity)."}]}
+{"id": "function_valid_3936", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSRIDQSKLELEERLVTVNRVAKVVKGGRRFRFAALVVVGDKNGHVGFGTGKAQEVPEAIRKAVEDAKKNLIEVPMVGTTIPHEIIGRFGAGNVLLKPASEGTGVIAGGPVRAVLELAGLADILSKSLGSNTPINMIRATLQGLSELKRAEDVAKLRGKSVEDLLG", "output": "With S4 and S12 plays an important role in translational accuracy.; "}]}
+{"id": "function_valid_3937", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAKIRIHEIAKELGYDSKEIIEKANELGLGIKTASNAVEPEIAAAIYEYIQTREIPEAFKKNIKTPTAKKPKKENIKEQEKLNESEKKEPKKEEKLKQEVKKEELKVEKENVKEEEKQEIIDAHKPQSLASATLAKRRGLVIVKKKKDEEEIQVKKEEVKNSNDISINNEERLSLKTMFSNADESLKKKKKEKKSFVASKKESTEKMNFLDEHDFGDISLDDEDEVVLPDFSVKEQEKPQNINKKQPNFIRQAVGNSAGFGLEGGIQRRSRKKPPKKIEKKEVEEVSSVAISKEIRVYEFADKIGKSTSEVISKLFMLGMMTTKNDFLDEDAIEILAAEFGIEINIINEADEFDYVKDYEEETDEKDLVTRAPVITIMGHVDHGKTSLLDYIRKSRVASGEAGGITQHVGAYMVEKNGRKITFIDTPGHEAFTAMRARGASITDIVIIVVAADDGVKPQTKEAINHAKAAGVPIIIAINKMDKEAANPDMVKTQLAEMEIMPVEWGGSYEFVGVSAKTGMGIEDLLEIVLLQADILELKANPKSFAKASIIESSVQKGRGAVATIIVQNGTLTVGSTVVAGEAYGKVRAMSDDQGKALKEIKPGECGVIVGLSEVADAGEILIAVKTDKEAREYANKRHEYNRQKELSKSTKVSIDELGAKIKEGNLKALPVILKADVQGSLEALKASLEKLRNDEIKVNIIHSGVGGITQSDIELASASENSIVLGFNIRPTGEVKERAKDKGVEIKTYNVIYNLLDDVKALLGGMMSPIISEEQLGQAEIRQVINVPKIGQIAGCMVTEGVINRGAKIRLIRDGVVVYEGNVSSLKRFKDDAKEVAKGYECGVGIEGCDDMRVGDYIESYKEVEEQASL", "output": "One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex."}]}
+{"id": "function_valid_3938", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKTIVALGLLALATAASGQFLQDCTNALDGLYAIGNCESQFLTCSGGIARIMDCPADLIYNEPLLICDWRHNVVGCEGSGEASGEQSGEGSGEASGEGSGEASGEGSGEASGEGSGSGEGSGEENNVCEGLEDGAYSSGGCTTYYFFCTDNTARFLSCPTPLFYDVATQKCAWKALVEECNGEIIIDGSGETSGEGSGEASGENSGENSGEGSGEFEPTCDGKADGIYPNGVCVPNFLTCSGGIARVMNCPASLIFNPDILVCDWPRDVAECHGLSTPAPVCEDDGYFSFGQCSSSFTACTNGRAIVMFCPAGLKFSQANQRCDYDDLVNECQEASGEESSGEASGEQSGEGSGEASGEASGEASGENECVSLDNGLHAIGCSPRVLSCQNGHVDIFECPSSLVFNEQTLICDYPQTSLKCLIEDTLLIDETPITPFDCSTNGLFSDGLCSATYHQCSAGQLINFTCAETNAVFSAANAECVDSSTLLQCH", "output": "Required for polar body extrusion during cytokinesis in embryo development. Affects cortical granule size. Shown to have roles in meiotic chromosome segregation, osmotic barrier function and polarization in conjunction with cpg-2. Binds chitin (By similarity)."}]}
+{"id": "function_valid_3939", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEAIFELLGYQYKASLNWDIYIPLLKGYNKGKNIFIKKILFIKNNGLIINGFPYINRGIIKAKIIKHIRDKKQICFKSKKRKGFKLKKGHRQYLTKIKIIYIEF", "output": "This protein binds to 23S rRNA in the presence of protein L20."}]}
+{"id": "function_valid_3940", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKDQPIGMFDSGVGGLSTLRDLRALLPHEDIIYYADTGNCPYGGRSHEEIVALSERITYILLERGVKLIVVACNTATLHAVDYLREHFSISFVGMEPGIKPAIAQTKTGVVGVMATQATVAGERFQRLIARYAGDVQVVPQACPGLVELIEAGELQSETTRDAVARYVAPLLKAGADTIVLGCTHYPFLRSLIADVAGPNVALLDTGAAVARQTQRLLAAADLLNPQTSQGSIEWLTSGDPAHFAKIRQCLEIE", "output": "Provides the (R)-glutamate required for cell wall biosynthesis."}]}
+{"id": "function_valid_3941", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPLLLSGKEFRDDLESACCLAIQTPLEGGAETRLLRRLKAAGYRTQITSVRGFGDPEVFLLKLHGIRPPHLGHQNIGRNGALGEVQEVIPQLHELLSEEQPLALWLLEGQVLSRSELLALCDLSEKDPQLKIVVEMGGERKLKWQSMRKFLEQ", "output": "NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration."}]}
+{"id": "function_valid_3942", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGKIIGIDLGTTNSCVAIMDGNTTRVIENSEGARTTPSIIAYQEDGEILVGASAKRQAVTNPRNTIYAAKRLIGRKFDEKEVQKDIDLMPYTISRADNGDAWVEVRGQKLAPPQISAEVLRKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAFGLDKTDKGDRKIAVYDLGGGTFDVSIIEIADVDGEKQFEVLSTNGDTFLGGEDFDQRIIDYIITEFKKEQGVDLAKDVLALQRLKEAAEKAKIELSNSAQTDINLPYITADASGPKHLNIKLTRSKLESLVEDLIERTIAPCRTAIKDAGVSVSDIDDVILVGGMTRMPKVQEKVKEFFGKDPRKDVNPDEAVAVGAAVQGQVLSGDRKDVLLLDVTPLSLGIETLGGVMTKMITKNTTIPTKFAQTFSTADDNQPAVTIKVFQGEREMASGNKMLGEFNLEGIPPAARGVPQIEVAFDIDANGILNVSAKDKASGKENKITIKANSGLSEDEIQKMVKDAELNAADDKKKLELVQARNQGEAAVHSVKKSLGEHGDKLDAGEKTAIESAVKDLEEALKGEDKDAIDAKTTALMTASQKLGEKMYADAQAAGGPEAAAAAAAGAAGASAGAAAADDNVVDAEVKEVKKD", "output": "Acts as a chaperone."}]}
+{"id": "function_valid_3943", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRIGILGGTFDPIHYGHIRPAIEVKHALALDKILLMPNHIPPHKQQPNLTTAQRLKMVADVCSQLDGFELCDIEAKRDTPSYTVVTLEQLKSLHPEHELFFIMGMDSFLQLKSWYEWQRLFDFAHLVVCQRPGWQLDAAHPMQQILTARSHAHQETHEGHAKNTHKNSGQIFPVTITPQDISSTQIREQLAKGEIPVDLLMPVTLDYIQNQQLYLP", "output": "Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)."}]}
+{"id": "function_valid_3944", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MMTPTIPVALFDRLLVEGISPHELVRRKLMCLFNSCAVPGGETLPPLLTRGMPEWHEVNVGDKRVLNWFCRELRAAILRYEPSINMLKVSVKDAHHQTLALSLEAMLQDESEPLRLEIAYSNGRWR", "output": "Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway."}]}
+{"id": "function_valid_3945", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGAQLRVYRQRIKSTQSMGKLFKAMELIATSRISKARSRVQASLPYANAITRAVSVVASQSEIHHPLTTEPEQILRAAVLVLTSNRGLAGSYSASVLKQAEQLNTLLQADGKEVKTYLVGNKAQAYFQFRNRSFTKAWVNPTDAPEFATAQEISKTLLEDFAEEFEKDGVDEIHVVYTRFKSMVVQEPTVIRLLPLEVSEEEVSESSDLLPLYEYEPEPEAVLDALLPRYIEARIFNVMLQAAASELAARQRAMKSASDNARDLVKKFTRLANTARQAEITQELSEIVAGADSLNAS", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex."}]}
+{"id": "function_valid_3946", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGIAHTEWESVIGLEVHVELNTESKLFSPARNHFGDEPNTNISPVCTGMPGSLPVLNKDAVRKAVLFGCAVEGDVALFSRFDRKSYFYPDSPRNFQITQYEHPIVRGGCIRAVVEGEEKTFELAQTHLEDDAGMLKHFGDFAGVDYNRAGVPLIEIVSKPCMFSAEDAVAYANALVSILGYIGISDCNMEEGSIRFDVNISVRPRGSRELRNKVEIKNMNSFTFMAQALEAEKRRQIEEYLSHPNEDPKKVVPAATYRWDPEKKKTVLMRLKERAEDYMYFVEPDLPVLQITETYIDEVRQTLPELPHSKYMRYITDFDIAEDLAMILVGDRHTAHFFETATMSCKNYRALSNWITVEFAGRCKAKGKTLPFTGILPEWVAQLVNFIDRGVITGKIAKEIADRMVSSFGESPEDILRRHPSLLPMTDDHALRAIVKEVVAQNTASVADYKNGKAKALGFLVGQIMKRTEGKAPPKRVNELLLAAMRDM", "output": "Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)."}]}
+{"id": "function_valid_3947", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIENWHRGFVLHRREYSETSLLVDFFTEEHGRITLLAKGARRPHSPLKAVLQPFTPLLLRWSGKGDLKTLTKAEPASLTLPMQTLALYSGFYVNEVLARVLENQTAYPELFQHYLQCMTRLATQPEQIEPILRTFEFQMLKALGYGVNFSICAATGDPVSPSMTYQFRENQGFIASLLQNNYTFLGKDLLAFEQLDFSDKATLQAAKRFTRMALKPYLGSQPLKSRELFQNILPNKLKSG", "output": "Involved in DNA repair and RecF pathway recombination."}]}
+{"id": "function_valid_3948", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAKVSSIKKNESRKKKSQSLHNKRLALKSKIYDKNISLEERFSLVMSLAQLPRNSSSTRIRNRCELTGRPRGVTRKFGISRNKLRELIGRGLVPGVVKSSW", "output": "Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site."}]}
+{"id": "function_valid_3949", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAVKERVGVVVSDKMDKTVVVAIENRSPHPKYGKIVVKTQKFKAHDAENQAKQGDRVRIRETRPLSKTKRWEVAEILTDS", "output": "One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA."}]}
+{"id": "function_valid_3950", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDIKRTILIAALAVVSYVMVLKWNDDYGQAALPTQNTAASTVAPGLPDGVPAGNNGASADVPSANAESSPAELAPVALSKDLIRVKTDVLELAIDPVGGDIVQLNLPKYPRRQDHPDIPFQLFDNGGERVYLAQSGLTGANGPDARASGRPLYAAEQKSYQLADGQEQLVVDLKFSDNGVNYIKRFSFKRGEYDLNVSYLIDNQSGQAWSGNMFAQLKRDASGDPSSSTATGTATYLGAALWTASEPYKKVSMKDIDKGGLKENVSGGWVAWLQHYFVTAWIPAKSDNNVVQTRKDSQGNYIIGYTGPVISVPAGGKVETSAMLYAGPKIQSKLKELSPGLELTVDYGFLWFIAQPIFWLLQHIHSLLGNWGWSIIVLTMLIKGLFFPLSAASYRSMARMRAVAPKLAALKERFGDDRQKMSQAMMELYKKEKINPLGGCLPILVQMPVFLALYWVLLESVEMRQAPWMLWITDLSIKDPFFILPIIMGATMFIQQRLNPTPPDPMQAKVMKMMPIIFTFFFLWFPAGLVLYWVVNNCLSISQQWYITRRIEAATKKAAA", "output": "Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins."}]}
+{"id": "function_valid_3951", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKTDIHPKYVAAKIKCACGTVIETRSTSGDISVEICSNCHPFFTGKSKLVDTTGRVDKFKKKYKMK", "output": "Binds the 23S rRNA."}]}
+{"id": "function_valid_3952", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTSIFFNRHYPTLESACERWGLEFDANAEFELVFENDILTLIKRDEPKLKGIFVDFVTGAVAHRRKFGGGRGQSIAKAVGLKQGVTPTVVDGTAGLGRDAFVLASLGCKVIMVERHPIVAALLEDGLRRGYEDTEIGDWMRERMSLFHGSSIDSLADAPQASNTEVDVVYLDPMYPHREKSALVKKEMRVFQSLVGADLDADGLLAPAMALASKRVVVKRPDYADDLDGVKPSMVIATKKNRFDVYVKAAMTA", "output": "Specifically methylates the guanosine in position 1516 of 16S rRNA."}]}
+{"id": "function_valid_3953", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MANIKSAKKRAVQSEKRRKHNASRRSMVRTFIKKVYAAIAAGDKDAAQKAFNEMQPIVDRQSCKGLIHKNKAARHKSNLVAQINAMQ", "output": "Binds directly to 16S ribosomal RNA."}]}
+{"id": "function_valid_3954", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSTWLLPENIADVLPSEARKIEELRRRLLDRFRSYGYEMVMPPLLEYLESLLTSGGADLRLRTFKLVDQLSGRTLGLRADITPQVARIDAHLLNRQGVTRLCYAGHVMHTRPRGLHATREQIQIGAEIYGHAGLEADLEIQQLMLDALHLAGLSRIRLDLGHAGVLAALLARDAQAAERGESLYDALSGKDVPLLNELTDDLGADTRAALRALPNLYGDASVLAEARTRLPVLPEITRALDDLAQLASQAKGVEVAIDLADLRGYAYHSGAMFSAYIDGVPNAIARGGRYDHVGQAYGRSRPATGFSLDLRELARISPVEARGTAILAPWAQDDALCAAVAALRDAGEVVIQALPGHDHVLDEFACDRSLVERNGAWVVEPR", "output": "Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine."}]}
+{"id": "function_valid_3955", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTTPHSPKTIDELMSRANDMAGLTLGQLADSHGFITPANLKRDKGWVGQLIEHELGALAGSRPEPDFLHLGIELKTIPVDKNGKPIETTYVTVAPLIDIQGLTWETSVVCHKLQTVLWIPIQGDRDIPVSQRQIGSPILWRPNEEELALLKQDWEEIMEFIALGQVKQLTARHGEVLQLRPKGANSRSVTQSIGPNGSTQMTNPRGFYLKIPFTQSILSRAFGIYTQATSR", "output": "Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair."}]}
+{"id": "function_valid_3956", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETLADHEGRHLLPSVVHYQQQGHSVGYDARTNAALDTANTISSVKRLMGRSLADIQQRYPHLPYQFQASENGLPMIETAAGLLNPVRVSADILKALAARATEALAGELDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGQEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIPDRSDNRVQRELLDAAIAAKIALSDADSVTVNVAGWQGEISREQFNELIAPLVKRTLLACRRALKDAGVEADEVLEVVMVGGSTRVPLVRERVGEFFGRPPLTSIDPDKVVAIGAAIQADILVGNKPDSEMLLLDVIPLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRSLARFALRGIPALPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLTDSEIASMIKDSMSYAEQDVKARMLAEQKVEAARVLESLHGALAADAALLSAAERQDIDDAAAHLSEVAQGDDVDAIEQAIKNVDKQTQDFAARRMDQSVRRALKGHSVDEV", "output": "Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU."}]}
+{"id": "function_valid_3957", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTSTDQGSWARSEGDSWDIVSSVGYTALGVSAQRAVESERPDALIDDPFAKHFVLAAGEPHLIETITKRDAPQASPFEYLRGMGMRSRFFDEFFLEAAASGITQAVILAAGLDARAHRLAWPAGVTVYELDQPQVLAFKDGVYAQQGAEPTCDRRTVAVDLRDDWPAALKEAGFDAGRPTAWSAEGLLPYLPAAAQELLFERMVELSAPGSRAAIEGPTGTLGMSQFAKVEQKYRSEKDTFGKIDITELFYDEEKTPPVEWFSVRGWSTQGLDMFDLAERYGVRHPEVPEDIRELAGAMHYLTCTLPA", "output": "Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity."}]}
+{"id": "function_valid_3958", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQCPYCQHTNSRVLESRSSEGGQSIRRRRECLNCKHRFTTYERIEFVPITVIKHDGKKESFDASKLLRGMVRACEKTGISHQRLETIVDDIEAYLQQRPQREVTTHEIGQLVLKYLREENEVAYIRFASVYGRFKGIKDFVETLDQLQEETISSPMSQWSKSSTRDRDQSQTSPCLSLTHNGSENSR", "output": "Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes."}]}
+{"id": "function_valid_3959", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAAITNNPDKEKALGLVLNQIERNFGKGSIMRLGDAARMKVETISTGALTLDLALGGGLPMGRVVEIYGPESSGKTTLALHAIAEVQKAGGVAAFVDAEHALDPTYSAALGVDINNLLVAQPDTGESALEIVDQLVRSAAVDVVVIDSVAALVPRAEIEGEMGDTQVGLQARLMSKALRKIAGNIGKSGCVVIFLNQLRQKIGITYGSPEVTTGGTALKFYASVRLDIRRIQTLKKGSEGEYGIRAKVKVAKNKVAPPFRIAEFDIIFGQGISRMGCMLDLAEQSDVVLRKGAWYSYNGDNISQGRDNAVKYLEENPKIAETIEQQVREKLELGSLSFAISQGDGEEEE", "output": "Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage."}]}
+{"id": "function_valid_3960", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPQHDQLHRYLFENFAVRGELVTVSETLQQILENHDYPQPVKNVLAELLVATSLLTATLKFDGDITVQLQGDGPMNLAVINGNNNQQMRGVARVQGEIPENADLKTLVGNGYVVITITPSEGERYQGVVGLEGDTLAACLEDYFMRSEQLPTRLFIRTGDVDGKPAAGGMLLQVMPAQNAQQDDFDHLATLTETIKTEELLTLPANEVLWRLYHEEEVTVYDPQDVEFKCTCSRERCADALKTLPDEEVDSILAEDGEIDMHCDYCGNHYLFNAMDIAEIRNNASPADPQVH", "output": "Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress."}]}
+{"id": "function_valid_3961", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAKRKQNVRSKRKVKKNIESGIVHIRSTFNNTIVTITDMQGNAISWATAGNMGFKGSRKSTPFAAQLASETAAKTAMDNGMRTVEVNVKGPGAGREAAIRALQAIGLEVTAIRDVTPVPHNGCRPPKRRRV", "output": "Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome."}]}
+{"id": "function_valid_3962", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDPRSEVILRQHDYLKGRVLLINAPNDALVSQLPTEIDASVWTWNYADYQGFLNAGATAHFSVEFPLQEFDQAIIFVPKSKELLNYILHVVMSHLKIDQSVFLVGEKKGGVERAAKQLQSFGKILKLDSARHCQLWHLKIEKTEKIKPLESWLKTYTVQVNEQELTICALPGVFSQTHLDVGTAVLLPYLNQVKSGRIADFGCGAGIISCYLAKANSSNIIHALDIDAFALQSTEMTFSRNGIGSDQLRLQPVTGIADAPTELDAIVSNPPFHQGIHTNYDASEGLCQNAKKHLKASGELWIVANRFLNYPILIEKHFGQCEIKTDLQGFKVLYACA", "output": "Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle."}]}
+{"id": "function_valid_3963", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MERYQQLFKQLAAKKEGAFVPFVQLGDPSPAMSLNIIDTLIAAGADALELGIPFSDPLADGPTIQNAALRAFAAGVTPAICFEILAEIRQKHPTIPIGLLMYANLVFHNGIDHFYQRCAEVGVDSVLIADVPFEESAPFRAAALRHGIAPIFICPPNADDDLLREIASHGRGYTYLLSRAGVTGAENHGQLPLNHLVDKLREYNAAPALQGFGISEPAQVKASLAAGAAGAISGSAIVKIIEKNVAQPVEMLVQLTRFVTEMKAATRS", "output": "The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate."}]}
+{"id": "function_valid_3964", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLFNDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVIAPSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTYRFTIDAFRRHCMMNGLDSIGLTLQHDDAIAAYEAKQPAFMN", "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."}]}
+{"id": "function_valid_3965", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLATTFVMTLASICAWLIDTWILIPLNLIYLRTLAFILVIAVVVQFTEMVVRKTSPVLYRLLGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAVADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL", "output": "Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR."}]}
+{"id": "function_valid_3966", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIIERLIGNLRDLNPLDFSVDYVDLEWFETRKKIARFKTRQGKDIAIRLKDAPKLGLSQGDILFKEEKEIIAVNILDSEVIHIQAKSVAEVAKICYEIGNRHAALYYGESQFEFKTPFEKPTLALLEKLGVQNHVLSSKLDSKDRLTVSMPHSEPNFKVSLASDFKVVMK", "output": "Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly."}]}
+{"id": "function_valid_3967", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSSKEQNTPNEQASDEIETEQAKNQGADTAAEAADQRDERIAQLEAQLAESQGGVRDAQLRAQAEIENIRRRAELDVEKAHKFALEKFSNELLPVIDSLERALEVADKSNPELAAMIEGIDLTMKSLLGAVRKFGVEVVGDTNVPFNPEVHQAMSMMESEEVEPNHVMMVMQRGYTLNGRLLRPAMVAVAKSKG", "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding."}]}
+{"id": "function_valid_3968", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPKKTQQSVSFEASLQQLEQIVSRLESGDLALEEALNEFERGVQLARAGQQVLQQAEQRVQILLSDDKNAELTPFTPEKE", "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."}]}
+{"id": "function_valid_3969", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKNVTDSFVSLGHWRSAGSFGFNTDIFATNPINLSVVIGVLIFFGKGVFSDLLDNRKLRIVNTIRNSEELCGRAVEQLEKARARLRKVEMEADQFRMNGYSEIERDKLNLINSIYKTLEQLENYKNETIHFEQQRVINQVRLRVFQQALQGALGTLNSCLSNELHLRTINANIGMFGAMKEITD", "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "}]}
+{"id": "function_valid_3970", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MANHKSTQKSIRQDQKRNLINKSRKSNVKTFLKRVTLAINAGDKKVASEALSAAHSKLAKAANKGIYKLNTVSRKVSRLSRKIKQLEDKI", "output": "Binds directly to 16S ribosomal RNA."}]}
+{"id": "function_valid_3971", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MADEQFPAAATALEEYQSIEEQMASPEVVSNPDKLRKLGRRHAELGAIVDAYKAWLQVKDDLAAAQEMAGEDADFAEEAKRLEDELPGVEEKLRTALIPRDPDDARDTIMEIKAGTGGEEAALFAGDLLRMYTRYAEKRGWSVNVQSENTTELGGVKDVQIAIRAKGTPAPEDGVWASMKYEGGVHRVQRIPVTESQGRIQTSAAGVIVFPEADEDDDEIEIDPKDLKIDIFMSSGPGGQSVNTTYSAVRMTHLPTGITVNMQDEKSQIQNRAAALRVLKSRLLAMKHEQEAAEAADMRHSQVRSLDRSERIRTYNFPENRIVDHRTNYKAYNLDAVLDGDLQAVIDSDIQADEADRLANQK", "output": "Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA."}]}
+{"id": "function_valid_3972", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGAILGKKIGMTRLYNDKREAISCTVIQAGPCFVTQVKSAEKDGYDAYQIGIGERDEKKINKPMQGHYRKAGVTPGFMMAEFKKTEFSENLEAGNPVSVESFKEGEKVNVLGVSKGKGFAGVVKRHNFGGGSRTHGQSDRLRAPGSVGGSSDPSRTFRGTRMAGRMGGDNITVKNLEIVKIMPESNLLVIKGAVPGPKNSYVKIVSIKK", "output": "One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit."}]}
+{"id": "function_valid_3973", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MALVPIVVEQTSKGERSYDIYSRLLKERIIFLTGQVEDHMANLIVAQMLFLEAEDPEKDIYLYINSPGGVVTAGLAIYDTMNFIKPDVATLCTGQACSMGAFLLSGGAKGKRFALPNARVMIHQPLGGARGQATDIQIQAQEILKLKEMLTRKMAEHSGQPFEKVAADTERDNFMSAVEAMEYGLIDKVLTHRDIK", "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins."}]}
+{"id": "function_valid_3974", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MANTPQAKKRARQNEKARKHNASMRSMGRTYLKKVLSAIQTGDQAAAQAAYVSAVAVIDRIADKGLIHKNKAARHKSRLNAKLKAMAA", "output": "Binds directly to 16S ribosomal RNA."}]}
+{"id": "function_valid_3975", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGQKSNPNGLRLGIIKNWDSKWFANFKKTPQFIHEDFCIRNFINKNYSKALIAQIEIERSKKKDKEIIKINLHVAKSNIINGKDNESLKKITKQIEQITKKEVFFNVIEIKNPDKVAILVAKTMAEQLEQRFYFRRVQKMAIQKVLKTGVKGVKTLISGRLGGLEMARSEGYLEGRVPLNTLRADVEYAFTEAHTTYGSFGVKVWIFHGDVLPGETILDTRKPFAIKSNYISKNNKKSNNYKGDK", "output": "Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation."}]}
+{"id": "function_valid_3976", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAARLQEFYKEQVVPKLIEQFGYKSVMEVPRITKITLNMGLGEAINDKKIIENAVGDLTKIAGQKPVVTKAKKAIAGFKIRQGYPIGAMVTLRGERMFEFLDRFVTVALPRVRDFRGVSGRSFDGRGNYNIGVKEQIIFPEIEYDKIDALRGLNISITTTAKNDEEAKALLGAFKFPFRN", "output": "This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs."}]}
+{"id": "function_valid_3977", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLSNILPLSIGAIFGTTARWLLNLAVPASLSPATGNLFANWTGALLIGIFAETVSHPQWKLLLITGFFGSLTTLSGFSLETVTLLQSNRPASALANIFLHTAGSLLLTWLGLKIGTAVK", "output": "Important for reducing fluoride concentration in the cell, thus reducing its toxicity."}]}
+{"id": "function_valid_3978", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MALTKAEMAEKLFDEVGLNKREAKEFVDAFFDVLREALEQGRQVKLSGFGNFDLRRKNQRPGRNPKTGEEIPISARTVVTFRPGQKLKERVEAYAGSGQ", "output": "This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control."}]}
+{"id": "function_valid_3979", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTNPFDSAGSKAPPKPFTVSEGRREVRSFVLRQGRFTPAQQRAFDERWPRFGIDYNGQPRDLDATFGRPAHKVLEIGFGNGAAMRFAAQHDPSRDYIGIEVHAPGVGRLLNALADDNADHVRLYHHDAVEVLQNEIADGALDEVRIYFPDPWHKKRHNKRRLLQPAFAELIVRKLRPGGRLHCATDWEDYAEQMWDVLDATAGLVNRAGPRGSVPRPDWRPQTHFETRGQKLGHGVWDLLYDRT", "output": "Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA."}]}
+{"id": "function_valid_3980", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MISYYFQGFALGVAMILPLGPQNAFVMNQGIRRQYHLMIALLCALSDLVLISAGIFGGSALLMQSPWLLALVTWGGVAFLLWYGFGALKTAMSSNLELASAEVMKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLAMEPKRWFALGTISASFLWFFGLALLAAWLAPRLRTAKAQRIINILVGVVMWLIAFQLAREGVAHMHALFN", "output": "Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine."}]}
+{"id": "function_valid_3981", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MELLLLSNSTLPGKAWLEHALPLIANQLNGRRSAVFIPFAGVTQTWDEYTDKTAEVLAPLGINVTGIHRVADPLAAIEKAEIIIVGGGNTFQLLKESRERGLLAPMADRVKRGALYIGWSAGANLACPTIRTTNDMPIVDPNGFDALDLFPLQINPHFTNALPEGHKGETREQRIRELLVVAPELTVIGLPEGNWIQVSNGQAVLGGPNTTWVFKAGEEAVALEAGHRF", "output": "Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids."}]}
+{"id": "function_valid_3982", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGNPFELEADGLLAICIQHEMDHLVGKLFIDYLSPLKQQRIRQKVEKLDRLNARA", "output": "Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions."}]}
+{"id": "function_valid_3983", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIDKSAFIHPTAIVEDGAVIGANAHIGPFCIVGPQVEIGEGTVLKSHVAVNGQTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHVAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVHQFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREGLVAIRNAYKLLYRSGKTLDEAKLEIAELAEKHPEVKAFTEFFERSTRGPIR", "output": "Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell."}]}
+{"id": "function_valid_3984", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "METATLIAISISGLIVSFTGYALYTAFGQPSQQLRDPFEEHGD", "output": "May play a role in photosystem I and II biogenesis."}]}
+{"id": "function_valid_3985", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAAVLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSHITVVVSDR", "output": "This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).; "}]}
+{"id": "function_valid_3986", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTLPDFRLIRLLPLASLVLTACTLPGHKGPGKSPDSPQWRQHQQEVRHLNQYQTRGAFAYISDDQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGNVQLVDNKGQRYTADDAEEMIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEVNYRQDGKNWKVVYGGYDSKTQPAMPANMELSDGSQRIKLKMDNWIVK", "output": "Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein."}]}
+{"id": "function_valid_3987", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQTGETLLIIADDPATTRDIPGFCTFMEHDLLAQETEGLPYRYLLRKAH", "output": "Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin."}]}
+{"id": "function_valid_3988", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSREEANTRETVTAYREYKQVIQTISDAEEMIKDASGDPELEEMAKEELKESKAAKEEYEEKLKILLLPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAETQGWRFEVMESSVNGVGGIKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDIDPKDLRVDIYHASGAGGQNVNKVATAVRMVHIPTGIKVEMQEERTQQKNRDKAMKIIRARVADHFAQIAQDEQDAERKSTVGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTILSGKMDEVIDALVMYDQTKKLESLNN", "output": "Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA."}]}
+{"id": "function_valid_3989", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLLEKNSKSGGRNNNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERRYILAPKGLKAGDQIQSGVDAAIKAGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGTYVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRPTVRGTAMNPVDHPHGGGEGRNFGKHPVSPWGLQTKGKKTRSNKRTDKFIVRRRSK", "output": "One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome."}]}
+{"id": "function_valid_3990", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAKKIAAQFRLLLPAGKATPAPPVGPALGQRGVNIMEFIKRFNAATASMGDVLVPVDVTVFADKSFTFEVRTPPASFLLKKAAKVEKGSGEPNKVTVGKVTRAQVEEIAKQKMKDLNTEDLEAAVRIIEGTARSMGIQVVD", "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors."}]}
+{"id": "function_valid_3991", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTTLTAQQIACVYAWLAQLFSRELDDEQLTQIASAQMAEWFSLLKSEPPLAAAVNELENCIATLTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQEIKRLLVEAGMETSGNFNEPADHLAIYLELLSHLHFSLGEGTVPARRIDSLRQKTLTALWQWLPEFVVRCRQYDSFGFYAALSQLLLVLVESDHQNR", "output": "Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor."}]}
+{"id": "function_valid_3992", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MALNLEQKKAMVAEITDIANQAVSAVAADYRGLTVSEMSDLRKSAREARVHMRVYRNTLARRAFKETTYACLEEVLTGPIVLFFSQEEPGAAARLIEKFIKEHERLEVKGLALGGELLPAEKLKAVARLPSREEALSQLAAVLLAPVTKLVRTLNEPIAQVARVMAAVRDQKAA", "output": "Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors."}]}
+{"id": "function_valid_3993", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKRVFLWLIFVLAFHKLLAEKIGDIASVVGVRDNQLIGYGLVIGLNGTGDKSGSKFTMQSISNMLESVNVKISADDIKSKNVAAVMITASLPPFARQGDKIDIHISSIGDAKSIQGGTLVMTPLNAVDGNIYALAQGAITSGNSNNLLSANIINGATIEREVSYDLFHKNAMVLSLKSPNFKNAIQVQNTLNKVFGNKVAIALDPKTIQITRPERFSMVEFLALVQEIPINYSAKNKIIVDEKSGTIISGVDIMVHPIVVTSQDITLKITKEPLNNSKNTQDLDNNMSLDTAHNTLSSNGKNITIAGVVKALQKIGVSAKGMVSILQALKKSGAISAEMEIL", "output": "Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation."}]}
+{"id": "function_valid_3994", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQQGIHPDYHPVEVTCSCGNTFVTRTAGKEDHMFVDVCSQCHPFYTGKQKILDTGGRVARFEKRYGKKSK", "output": "Binds the 23S rRNA."}]}
+{"id": "function_valid_3995", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKKKIAEYEVGEQVDIFLLIKTATKGIASNGKPFLTVILQDPSGDIEAKLWDVSPEVEKQYVAETIVKVAGDILNYKGRIQLRVKQIRVANENEVTDISDFVEKAPVKKEDMVEKITQYIFEMRNPNIQRLTRHLLNKHQNEFLDYPAATKNHHEFVSGLAYHVVSMLDLAKAISNLYPSLDKDLLYAGVILHDLGKVIELSGPISTTYTLEGNLLGHISIMVNEIGKAADELQIDAEEVLILQHIVLSHHGKAEWGSPKPPLVKEAEILHYIDNLDAKMNMMDRALGRTKPGEYTERVFALDNRSFYKPSFHN", "output": "Shows a 3'-5' exoribonuclease activity."}]}
+{"id": "function_valid_3996", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGKIRKLDDQLSNLIAAGEVVERPASVVKELVENSIDANSTSIEIHLEEAGLSKIRIIDNGDGIAEEDCIVAFERHATSKIKDENDLFRIRTLGFRGEALPSIASVSELELITSTGDAPGTHLIIKGGDIIKQEKTASRKGTDITVQNLFFNTPARLKYMKTIHTELGNITDIVYRIAMSHPEVSLKLFHNEKKLLHTSGNGDVRQVLASIYSIQVAKKLVPIEAESLDFTIKGYVTLPEVTRASRNYMSTIVNGRYVRNFVLMKAIQQGYHTLLPVGRYPIGFLSIEMDPMLVDVNVHPAKLEVRFSKEQELLKLIEETLQAAFKKIQLIPDAGVTTKKKEKDESVQEQFQFEHAKPKEPSMPEIVLPTGMDEKQEEPQAVKQSAQLWQPPKQEWQPPQSLVREEQSWQPSTKSIIEEPIREEKSWNSNDEDFELEELEEEVQEIEEIEMNGNDLPPLYPIGQMHGTYIFAQNDKGLYMIDQHAAQERINYEYFRDKVGRVAQEVQELLVPYRIDLSLTEFLRVEEQLEELKKVGLFLEQFGHQSFIVRSHPTWFPKGQETEIIDEMMEQVVKLKKVDIKKLREEAAIMMSCKASIKANQYLTNDQIFALLEELRTTTNPYTCPHGRPILVHHSTYELEKMFKRVM", "output": "This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex."}]}
+{"id": "function_valid_3997", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPVLNLKSDLADADDLETLMAGIGRRARAAGRAMALAPAQTKDLGLRAIAEQIRTSAPAILRENARDVSAAQAAGLTNAIIDRLTLDEGRVAAIAEAVEKVAGLADPVGRQLAAFERPNGLLIERISVPLGVVGVIFESRPNVTADAGALCLKAGNAAILRAGSDSHRTATAIAAAMSEGLARAGLPADAIQLVPTRDRAAVGLMLTGLGGCVDVIVPRGGRSLVERVQAEAKVPVFAHLDGICHVYVAEGADLGMARSLLLNSKMRRTGICGAAETLLVDAAVAETHLKPLVEALLESGCAVRGDAATQAADPRVSAATDADWRTEYLDAIISAKVVDGLDAAIAHIEANGSHHTDAIITDDTNAAARFLNEVDSAIVTHNASTQFADGGEFGFGAEIGIATGRMHARGPVGVEQLTTFKYRVHGSGQTRP", "output": "Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate."}]}
+{"id": "function_valid_3998", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKLHVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL", "output": "One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA."}]}
+{"id": "function_valid_3999", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRRANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFLDDPLYLFRVWDGGMSFHGGLIGVIVVMFIFAHRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNFPFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYIRKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVIMMVWAYRRSPQQHVS", "output": "Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins."}]}
+{"id": "function_valid_4000", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEISWGRALWRNFLGQSPDWYKLALIIFLILNPLIFIISPFVAGWLLVAEFIFTLAMALKCYPLLPGGLLAIEAVFIGMTSAEHVREEVAANLEVLLLLMFMVAGIYFMKQLLLFIFTRLLLSIRSKMLLSLSFCMAAAFLSAFLDALTVVAVVISVAVGFYGIYHRVASSRTEDTDLQDDSHIDKHYKVVLEQFRGFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAKAAGWHFGDFFLRMSPVTVPVLICGLLTCLLVEKLRCFGYGETLPEKVREVLQQFDDQSRQQRTRQDKIRLIVQAIIGVWLVTALALHLAEVGLIGLSVIILATSLTGVTDEHAIGKAFTESLPFTALLTVFFSVVAVIIDQQLFSPIIHFVLQASEHAQLSLFYIFNGLLSSISDNVFVGTIYINEAKAAMESGAITLKQYELLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVWMALPYTLVLTVVGLLCVEFTLAPVTEWFMQMGWIATL", "output": "Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons."}]}
+{"id": "function_valid_4001", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRTSHMLEHLMEALRCLPGVGPKSAQRMAFHLLQRDRKGGLQLAEALSQAMTEIGHCNECRTFTEEETCHICTNPKRQDNGQICVVESPADIAAIEATGQYSGRYFVLMGHLSPLDGIGPSDIGLDVLDYRLRRGDITEVILATNPTVEGEATAHYIAELCNAHEVNASRIAHGVPVGGELELVDGTTLSHSLLGRHKI", "output": "May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO."}]}
+{"id": "function_valid_4002", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPQVAKYDTTGNRVGDIDLADNVFNEEVNEHVVHQVVTAQLATMRRGTASTKTRGEVSGGGRKPWRQKGTGRARHGSIRSPLWVGGGIVFGPRPRKHIKKVPKKVKKLALRSILSYKSQNEELIILDELKFDTPKTKQVVELLSNLNLEGKKVLIILPDKDANIYLSARNIPGVKTLVVDALNAFDLLNNDCIVMSEEAVKRVEEVLAR", "output": "One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.; "}]}
+{"id": "function_valid_4003", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPRRRIIGTRKILPDPKFSSELLAKFINILMIDGKKSIAEVIVYTALKNLSKRTDKKELEAFEIALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMRWIVESARKRVDKSMSLRLSNELYDALENKGTAVKKREEVHRMAEANKAFAHYRW", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."}]}
+{"id": "function_valid_4004", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAEIILNVEVRDGAGTGNARATRRAGKVPGVLYGGGKAPVNIAVKANEFRKSLYTGKLLGHLVTLQYGEEKQSVIAKAVQFHPVTDEPVHFDLYRVDEHQLIKIEVPVHFKNHETSVGLKKGGTLEVIRHTVELACPADKIPEELVIDLAGHDIGDVIRISEVKLPEGVKPAMDRDFVIANVKASSAAQSDAGDTTA", "output": "This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance."}]}
+{"id": "function_valid_4005", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MARLAGVDIPREKRLEIALTYIYGVGKTRAHETLAATGISADVRVKDLTDAQLVELRDYIEGNYKVEGDLRREVAADIRRKVEIGSYEGLRHRKGLPVRGQRTKTNARTRKGPKRTVAGKKKAR", "output": "Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites."}]}
+{"id": "function_valid_4006", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEMLLGTDIIEVDRIKRAIENGGRKFSEKVFTLNEIEYCESRKAGKYQSYAARFAAKEAVSKAFGTGIGKNAAFSEIEILKDSLGKPYVRLSGKAKEFYDSLGTAGISVSLSHCRAYAVAYAVISLGDSFKNKI", "output": "Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein."}]}
+{"id": "function_valid_4007", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDILKSIENEQIRTDLPKLEIGDFIKVHAKIKEGTRERIQVFEGTVIALKGSGLKETFTVRRISYGVGVERVFPVNSPRVDRIDVVRKGVVRRAKLYYLRDRVGKAAKIKEKLDRK", "output": "This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site."}]}
+{"id": "function_valid_4008", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKYSKNESRQRRKIRISKKVSGTAERPRLVVYRSNLHVYAQIVNDLDGATLVATSTLALGKNESGLHCNKGGAEKVGIEIARMAKEKNIDKVVFDRNGYLYHGRVKAVADGAREGGLEF", "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."}]}
+{"id": "function_valid_4009", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MARLLLVCLGGALGSGARYLTSAWALRAFGPDFPRGTLLVNVSGSFLLAGIMTASLQSEAVPPDLRLFLAAGVMGGFTTYSSFNYETLALVEQGRLAAAAAYLLATVLGCLAAAFAATLLVRWLAG", "output": "Important for reducing fluoride concentration in the cell, thus reducing its toxicity."}]}
+{"id": "function_valid_4010", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDSFVSTYLWPALIMIGQSLLLLVCLLVFIAYILLADRKIWAAVQLRRGPNVVGPFGLFQSFADLLKFMVKEPIIPAGANKAVFLLAPLVSVVLALSTWAVVPVANGWVIANINVGILYILAISSLEVYGIIMGGWASNSKYPFLGALRSAAQMVSYEVSIGLVIVTVLLCVGSLNLTDIVMSQQTGLGTKLGLPASFLDWHWLSLFPMFIVFFISALAETNRPPFDLPEAESELVAGFMVEYGSAPYMMFMLGEYAAVVLMCSLTTILFLGGWLPPVDIWILSWVPGIIWFMLKACFVFFMFAMVKAFVPRYRYDQLMRLGWKVFLPLSLAMVVIVAFVLKLTGWA", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone."}]}
+{"id": "function_valid_4011", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAAGGAEEATKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANIKEGVAAAEAEEIKAKLEEAGATITLK", "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation."}]}
+{"id": "function_valid_4012", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MARVKRGVIARRRHKKILKLAKGYYGARSRVFRVAKQAVIKAGQYAYRDRRQRKRQFRALWIARINAGARQNGLSYSRLIAGLKKATIEIDRKVLSDLAVNEKAAFAAIVEKAKAVLA", "output": "Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit."}]}
+{"id": "function_valid_4013", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEPFRIHKGTAAVLMNDNIDTDQIIPKQYLKRIERTGFGKFLFDEWRYDNNRQENPNFPLNAPDRKGASILITGDNFGCGSSREHAPWALADYGFRVIIAGGFADIFYMNCMKNGMLPIVMDKEMREKLVKTDAREQIEVDLENEVITTSTHRFHFTIEKMWKEKLFNGLDEISITMQYEQEIKEYERRVATY", "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."}]}
+{"id": "function_valid_4014", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MVEVRVPATSANIGPGFDCLGVAVNIYNKFFVEEIEEGLIFEGCADKFKNENNLIYVAMKKCFDKIGYKPTGLRIKIESDIPVSRGLGSSAACVVGGIVSANELAGGVLNKKELLDLAVGVEGHPDNVNPAFCGGMTASISDNREVIYSKVKVSEGIKFCALIPDFTLSTEKARAVLPKSIDYKDGIFNVGRTALMISALNNGDFHLIKYACKDKLHQDYRAKLIENFYSIKEECEKLNSLGVFLSGAGPTIMVMLKEEDKRFSKNIKSFLETLKNKWEVRELKIDKLGTVVNNRKV", "output": "Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate."}]}
+{"id": "function_valid_4015", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MENISDLWNSALKELEKKVSKPSYETWLKSTTAHNLKKDVLTITAPNEFARDWLESHYSELISETLYDLTGAKLAIRFIIPQSQAEEEIDLPPAKPNAAQDDSNHLPQSMLNPKYTFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHYVIEHNPNAKVVYLSSEKFTNEFINSIRDNKAVDFRNKYRNVDVLLIDDIQFLAGKEQTQEEFFHTFNALHEESKQIVISSDRPPKEIPTLEDRLRSRFEWGLITDITPPDLETRIAILRKKAKAEGLDIPNEVMLYIANQIDSNIRELEGALIRVVAYSSLINKDINADLAAEALKDIIPNSKPKIISIYDIQKAVGDVYQVKLEDFKAKKRTKSVAFPRQIAMYLSRELTDSSLPKIGEEFGGRDHTTVIHAHEKISKLLKTDTQLQKQVEEINDILK", "output": "Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids."}]}
+{"id": "function_valid_4016", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTEMKILIVTLTYIEKSIIDEIVNNLSSYGLEVDILFDSRKYLPISAFNWERLQYDAEKVLSFLKSKYDFNYDSIIFLADSDGYIDGYNFVFGLTIDNFAIIFLNRLREEFYNRKPDLELFMKRVVKEVTHEAGHTLGLGHCNTIGCVMNFSNTVEDVDKKQARFCKNCIYKIENLSKYLQRK", "output": "Probable zinc metalloprotease whose natural substrate is unknown."}]}
+{"id": "function_valid_4017", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKKEIASHLLEIGAVFLQPNDPFTWSSGMKSPIYCDNRLTLSYPKVRQTIAAGLEELIKEHFPTVEVIAGTATAGIAHAAWVSDRMDLPMCYVRSKAKGHGKGNQIEGKAEKGQKVVVVEDLISTGGSAITCVEALREAGCEVLGIVSIFTYELEAGKEKLEAANVASYSLSDYSALTEVAAEKGIIGQAETKKLQEWRKNPADEAWITA", "output": "Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)."}]}
+{"id": "function_valid_4018", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MYCPFCHNEQSRVIDSRVIDSGTSIRRRRECAACKGRFTTIEKAVLSVVKRNGLAEPFSRDKLIRGVKRACQGRDVSDDALKKLAQEVEETVRSHGSSQVNANDIGLAILEPLRDLDEVAYLRFASVYKSFESADDFESEIRLMRRRDRDSF", "output": "Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes."}]}
+{"id": "function_valid_4019", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIKEAIVKIVNKEDLTYDEAYAVMNEIMGGETTSTQNAAFLAALSTKSAKAETTDEIAGCAAAMREHAVQVKTGMDVFEIVGTGGDNAQSFNISTTSALVAAAGGMKVAKHGNRAASSLCGTADCLEALGVNIDQSPEKCVELLNKVGMCFFFAQKYHTSMKYVGPIRKELGFRTVFNILGPLTNPGSPAMQLLGVYDEYLVEPLAQVLVSLGVKRGMVVYGMDKLDEISMSASTKICEIKDGWFRTTVISPEDFGFERCTKEDLKGGTPEENAKIVRDILGGQKGHKRNAVLMNAGASLYIGGKADSMKEGIELAAEIIDSGKALETLDKLIDVSNS", "output": "Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)."}]}
+{"id": "function_valid_4020", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MMRQSLQAVLPEISGNKTSSLRKSVCSDLLTLFNSPHSALPSLLVSGMPEWQVHNPSDKHLQSWYCRQLRSALLFHEPRIAALQVNLKEAYCHTLAISLEIMLYHDDEPLTFDLVWDNGGWRSATLENVS", "output": "Inhibits RpoS proteolysis by regulating RssB activity, thereby increasing the stability of the sigma stress factor RpoS during oxidative stress. Its effect on RpoS stability is due to its interaction with RssB, which probably blocks the interaction of RssB with RpoS, and the consequent delivery of the RssB-RpoS complex to the ClpXP protein degradation pathway."}]}
+{"id": "function_valid_4021", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTTGVERVLFRALGVSDREMNWKQYLCAILGLNMLGLAVLFFMLLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSMSTLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFLPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANSSHPFENPTALTNFVQMLAIFLIPTALCFAFGEVMGDRRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGTDSSINMEGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGRTPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQAASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS", "output": "Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel."}]}
+{"id": "function_valid_4022", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLATTFVMTLASICAWLIDTWILIPLNLIYLRTLAFILVIAVVVQFTEMVVRKTSPVLYRLLGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAVADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL", "output": "Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR."}]}
+{"id": "function_valid_4023", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTYRDRPLGELAISIPRATRLFRQYELDFCCGGKLTLQRAAARHSLDLVMLESQLAELDSTPDQHRDWRQAPLDELCAFIVTRYHQRHRDQLPELVLMAQKVEQVHTGKTGCPRGLAKQLDSLRQELDSHMMKEERILFPLIEQGEGARCHGPISVMEHEHRDAGELLDVIRFLTDNMTPPTGACTTWRALYAGISELINDLMEHVSLENNLLFPRALGDV", "output": "Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions."}]}
+{"id": "function_valid_4024", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEVRQSIHSDHAKQLDTAGLRREFLIDTVFDADRYTMVYSHIDRIIVGGIMPVTQSVSIGNEVGKQLGVGYFLERRELGVINIGGPGTIDVDGKCYEIGPREALYVGQGARDLRFASLDSACPAKFYYNCAPAHTHYPNRKITPAEVSPQTLGDTKSSNRRTINKYMVPEVLPTCQLSMGLTELEEGNLWNTMPCHTHERRMEVYFYFNMAPDSCVFHMMGEPQETRHIVMRNEQAVISPSWSIHSGVGTRAYTFIWGMVGENQVFDDMDHLAITDLR", "output": "Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate."}]}
+{"id": "function_valid_4025", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPIDFRMTKKGLILLIESYSSIESLKQEIMAKFNEARDFFSEGDEISLMLTQETSKPDDIVNIVSLLGNLGVRVKDILVGSLEKKNVKIGQKYDLVREKVTEVRGAQVIKRNLRSGQIVVHNYDIIVFGNVHPGAEIIAGGSIVIFGTARGILRAGYSVGDEAVIAALDLKPSLIQISGLISQDYNVYETPAVAHIRTGRIVVEKIESAKFEVKGGKI", "output": "Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization."}]}
+{"id": "function_valid_4026", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSKVKNIAVVAHDNCKKELLDFVDCNHNILSRHNLVATGTTGGLVEKMIMERVEQKADEGYEFKPVNRMKSGPLGGDQQLGAMISEGKIDVLIFFWDPMQPQPHDVDVKALLRLAVLYNIPTASNRSTAEFLISSPFFEGEFQRKETDFSSYTQRKL", "output": "Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate."}]}
+{"id": "function_valid_4027", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MARYLGPKLKLSRREGTDLFLKSGVRAIDSKCKIEQAPGQHGARKPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGANLLQLLEGRLDNVVYRMGFGATRAEARQMVSHKAIMVNGRVVSIASYQVSPNDVVSIREKAKKQSRVKAALELAEQREKPTWLEVDAAKMEGVFKRIPERTDLSADINEHLIVELYSK", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; "}]}
+{"id": "function_valid_4028", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MITTTALVPARRSAVRTLLATVTEHDGVSPLDEAALLALDGEDARHLLLTADGAATDTHAAEATAGSAASADPADPADPAAPADPADPADETLLGYVSVLGDGTVQGMVDPAHRRRGHGSALLRAALALRPDAGVWVHGALEGSLAFLTDAGLTETRRLLTLRRDLGGAQPLPSAPAPTLEGLRLDTFEESRDAEAWVAVNVRAFADHPEQGALTRADLEQRLAQPWFDAEDMLVALRDETLVGFVWIKREQPGATDRDAEIYVVATDPSVQGHRVAGHLMATVLERLERDGVPGVELYVEADNAPALRLYENWGFEVSGRDVQLRATERG", "output": "Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol."}]}
+{"id": "function_valid_4029", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKIKEGYMPFHEYKTYYRIVGEPSADKAPLLIHGGPGSSHNYFELMDDYAETGRQLIMYDQVGCGKSSLPEDPGVYVKETWAEELVALRKFLHLDELHMLGQSWGGMLEMYYLTSFDPQGIKSVMIDGSPASIKLWVQEQHRLIKYLSYEDRAAIAEAERTGDFTNVKYLAANDRYMEKYCWDDPDENSPEPLRRPTNGKRASLIAEGPNEFTENGTISDFDVTDQLHKIHVPVLVTSGTDDLCTPLIAKSVVDHIPGAKWHLFANSRHLALLDQHDEFIHVLDQWLAAND", "output": "Releases the N-terminal proline from various substrates."}]}
+{"id": "function_valid_4030", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRIFVYGSLRTKQGNSHWMTNALLLGEYSIDNYQLYSLGHYPGAVPGNGTVHGEVYRIDNATLAELDALRTRGGEYARQLIQTPYGSAWMYVYQRPVEGLTLIESGNWLDRDQY", "output": "May play a role in antibiotic biosynthesis."}]}
+{"id": "function_valid_4031", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "GLNRPSKRCLAGSAPCEFHKRSTCCSGHCIIWWCA", "output": "Probable neurotoxin with unknown target. Possibly targets ion channels."}]}
+{"id": "function_valid_4032", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKPLHAFPKRWLPWLIGGAFALVAISMMPSLMRHENVVQIRVSHAGAPMPDGFYLYQQLSAQGIRIKSITPSGDALIIHFDNEEQSLAAQKVLRRLLPDGFIVAQHDQAAHLSLA", "output": "Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR."}]}
+{"id": "function_valid_4033", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKAIKVNAGRTAAVQPARMPKLRDGYLLCKVHCVALNPADWKYLDFIGVQGVTLGADLSGVVEEIDPSCGAHFEKGDRIAAFVHGGNVSQPDDGAFAEYCLVKADLALKVPDAMSDEDAATLGVAVATCGQALYQGLELPLPGGAPYDGFLLVYGGSTSTGTLAIQYARLSGCKVIATASPHNWPLLKELGVEETFDYKDPDCAKKVRGIPICKAGYLTDGALIRAFTSDSLVLALDCIAEGDSAKICEDSISESKGGTICYLFQAKHSRADIVDKRVFAYTVFGEAFDKFGQSWPARAEDFARGKEFAALASQMLSDGQLRPHPVRLGKDGLEGVLDGLQQLRERKVSGAKLVYRVVETP", "output": "Oxidoreductase; part of the hps1-dma1 gene cluster that probably mediates the biosynthesis a derivative of cyclopiazonic acid (CPA) (Probable). The hybrid polyketide synthase-nonribosomal peptide synthetase (PKS-NRPS) nps1 might incorporates acetyl-CoA, malonyl-CoA, and tryptophan (Trp) and utilizes a C-terminal redox-incompetent reductase domain to make and release the tryptophan tetramic acid, cyclo-acetoacetyl-L-tryptophan (c-AATrp), as the first intermediate in the pathway (By similarity). In addition, the cluster also includes the tryptophan dimethylallyltransferase dma1, the FAD-dependent oxidoreductase toxD, the cytochrome P450 monooxygenase cyp3.1 and the methyltransferase DOTSEDRAFT_139328; the latter 2 being not present in all CPA-producing fungi but involved in additional modifications that occur in biosynthesis of a range of CPA and CPA-like products (Probable). Further studies are required to clarify whether the CPA-like hps1-dma1 cluster is functional or a non-functional relic reflecting evolution of D.septosporum (Probable)."}]}
+{"id": "function_valid_4034", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MVARGNVVSIGQIAPKHSSEVSFSVDPVSWEIGSLLQRGMLLEVATSNKPGLVCPQSNGCHEDMSLMTFMVSSSVIFPALVMCTQAGRDHEGDLPLLLPVVRGIGAPYEKELFAATKGVNTQKGALFSAAILAGAAGYLSQKSRHFQIGELFEVVAAMTKGIVRRELNPSVLEKKESLSNGEKLYLRHQVPGIRGELERGLPSVRDYAVPALKYAQDLGASLEASFLHTLITLMSQVDDTNIISRGGLESLKKVKTLSKEVLKEGSIFNKEGIDNYFYLENFCIDRGLSPGGSADLLAITISAYLLSEEKFKCKIM", "output": "Involved in the formation of 2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A, the prosthetic group of the acyl-carrier protein of the malonate decarboxylase."}]}
+{"id": "function_valid_4035", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTDVAKTLEELCTERGMRMTEQRRVIARILEDSEDHPDVEELYRRSVKVDAKISISTVYRTVKLFEDAGIIARHDFRDGRSRYETVPEEHHDHLIDLKTGTVIEFRSPEIEALQERIAREHGFRLVDHRLELYGVPLKKEDL", "output": "Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes."}]}
+{"id": "function_valid_4036", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "NTVSSFQDILMRMSKMQLGSSSEDLNGMITQLESLKLYRDSLGEAVMRMGDLHSLQSRNEKWREQLSQKFEEIRWLIEEVRHRLKNTENSFEQITFMQALQLLLEVEQEIRT", "output": "Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs). Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell. Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain. This domain is believed to allow recognition of RNPs to which the M1 protein is bound. Because the M1 protein is not available in large quantities until the later stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the nucleus before sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized. Furthermore, the RNPs enters the cytoplasm only when they have associated with the M1 protein that is necessary to guide them to the plasma membrane. May down-regulate viral RNA synthesis when overproduced (By similarity)."}]}
+{"id": "function_valid_4037", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKQVNMNRNERRQMRHKRVIKKIRRIDNDRPVMIVVKSNSHISAQVWDFNQNKIIASSSSVSLDLVNGNKENAAVVGTDIANKLLKMKIDEITFDHGGSKYHGRIAALADAARKAGLKF", "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."}]}
+{"id": "function_valid_4038", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVTIPPLVSRWFPVCGFRVCKISSPFAFTTPRWPHNDVYIGLPITLLHFPAHFQKFSQPAEISDKRYRVLLCNGHQTPALQQGTHSSRQVTPLSLRSRSSTFNK", "output": "Plays a role in modulating host cell signaling by binding to and degrading host RGS16 . Not necessary for virus replication ."}]}
+{"id": "function_valid_4039", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGQEDLMNRAEDVADQFLRVTKQYLPHLARLCLISTFLEDGIRMWFQWNEQRDYIEATWSCGYFLATCFVLLNLIGQLGGCVLILSRNFVQYACFGLFGIIALQTVAYSILWDLKFLMRNLALGGGLLLLLAESRSEGKSMFAGVPSMGESSPKQYMQLGGRVLLVLMFMTLLHFDFNFFSILQNLVGTALIILVAIGFKTKLAALTLVLWLLVINVYFNAFWTIPAYKPMHDFLKYDFFQTTSVIGGLLLVVALGPGGVSMDEKKKEW", "output": "Endoplasmic reticulum cargo receptor that mediates the export of lipoproteins by recruiting cargos into COPII vesicles to facilitate their secretion. Acts as a cargo receptor for lipoproteins bearing both APOB and APOA1, thereby regulating lipoprotein delivery and the maintenance of lipid homeostasis."}]}
+{"id": "function_valid_4040", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAVWQSATGKVYLPPSTPVARVQSTDEYIQRTNIYYHANTDRLLTVGHPYFNVYNNNGDTLQVPKVSGNQHRVFRLKLPDPNRFALADMSVYNPDKERLVWACRGLEISRGQPLGVGSTGHPYFNKVKDTENSNSYTTTSTDDRQNTSFDPKQIQMFIVGCTPCIGEHWEKAIPCAEDQQQGLCPPIELKNTVIEDGDMADIGFGNMNFKTLQQNRSDVSLDIVNEICKYPDFLKMQNDVYGDACFFYARREQCYARHFFVRGGKTGDDIPAAQIDDGMMKNQYYIPGGQDQSQKDIGNAMYFPTVSGSLVSSDAQLFNRPFWLQRAQGHNNGILWANQMFVTVVDNTRNTNFSISVYTENGELKNITDYKSTQFREYLRHVEEYEISLILQLCKIPLKADVLAQINAMNSSLLEEWQLGFVPTPDTPIHDTYRYIDSLATRCPDKSPPKEKPDPYAKFNFWNVDLTERLSLDLDQYSLGRKFLFQAGLQQTTVNGTKSISRGSVRGTKRKRKN", "output": "Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2."}]}
+{"id": "function_valid_4041", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "LECKDLGISIDDDNNRRLAVKEGDPLVVQFVNADREGN", "output": "Inhibition of trypsin."}]}
+{"id": "function_valid_4042", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNMGLFYGSSTCYTEMAAEKIRDIIGPELVTLHNLKDDSPKLMEQYDVLILGIPTWDFGEIQEDWEAVWDQLDDLNLEGKIVALYGLGDQLGYGEWFLDALGMLHDKLSTKGVKFVGYWPTEGYEFTSPKPVIADGQLFVGLALDETNQYDLSDERIQSWCEQILNEMAEHYA", "output": "Low-potential electron donor to a number of redox enzymes."}]}
+{"id": "function_valid_4043", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSNEVERVYPRLLDFVRKKYVSKNLLRVTLTGEDLIGFPEDQNGSHIKVFFPNQASGILQLPIREGDKVIWPEHKPVPRAYTVRQYRAQSNELDIDFVVHGEGTPGGGWALKAQTGSQLGLIGPGGPDPLIEPADWHIMAGDLSAVPAISAILEKMPSQAKGYVFLEVDDIEDKHDISHPEQMVIKWLVRDPNQAQPVLAMAIEQLPVPQGAESLSAFVAGENESVIACRKILRNEYRIARDKIYAIPYWKRGKNEEAYHEERHVVMDEEF", "output": "Involved in intracellular removal of iron from iron-vibriobactin complex. Vibriobactin is an iron-chelating compound involved in the transport of iron from the bacterial environment into the cell cytoplasm (By similarity)."}]}
+{"id": "function_valid_4044", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPQNEYIEQHIKKHGRRLDYEERKRKKEAREGHRVAKDAQTLKGWRAKQFAKKRYAEKVAMKKKIKAHQESKVKGPSTPKAEDGEALPTYLLDRQTNNTAKAISSSIKQKRLEKADKFQVPLPKVKGISEEEMFKVIKTGKSKSKSWKRMITKHTFVGEGFTRRPVKMERIIRPAALRQKKANVTHPELGVTVFLPILGVKKNPQSPMYTQLGVLTKGTIIEVNVSELGLVTAGGKVVWGKYAQITNEPDRDGCVNAVLLV", "output": "Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles (By similarity)."}]}
+{"id": "function_valid_4045", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTTVPVTDIQNDLITEFSEDNYPSNKNYEITLRQMSILTHVNNVVDREHNAAVVSSPEEISSQLNEDLFPDDDSPATIIERVQQPHTTIIDDTPPPTFRRELLISEQRQQREKRFNITVSKNAEAIMESRSMITSMPTQTPSLGVVYDKDKRIQMLEDEVVNLRNQQSNTKSSNNLDNFTRILFGKTPYKSTEVNKRIAIVNYANLNGSPLSVEDLDVCSEDEIDRIYKTIKQYHESRKRKIIVTNVIIIVINIIEQALLKLGFDEIKGLSTDITSEIIDVEIGDDCDAVASKLGIGNSPVLNIVLFILKIFVKRIKII", "output": "Required for viral crescent formation early during virus morphogenesis."}]}
+{"id": "function_valid_4046", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDLRTGEVITAPQAMNGVYTWEINNPLYFTITRHQQRPFLLNQDIITVQVRFNHNLRKELGIHKCFLNFQIWTTLQPQTGLFLRVFRYQVIKYLDNIGVISINNVIRAADHVLFNVIANTIECKLTHEIKFNVY", "output": "Increases viral DNA accumulation. Enhances infectivity and symptom expression."}]}
+{"id": "function_valid_4047", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "NEQSGKSQTVIVGSWGAKVS", "output": "D-galactose-specific lectin, binds the T-antigen structure Gal-beta1,3-GalNAc (Thomsen-Friedenreich-antigen-specific lectin). Potent and selective stimulant of distinct T- and B-cell functions. Shows a unique ability to specifically recognize IgA-1 from human serum."}]}
+{"id": "function_valid_4048", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "DLTPKVQVYSRFPASAGTKNVLNCFAAGFHPPKISITLMKDGVPMEGAQYSDMSFNDDWSFQRLVYADFTPSSDAVYTCKVDHETLKEPQVYKWDPEF", "output": "Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity)."}]}
+{"id": "function_valid_4049", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "METVYCTFDHKLSLSDISTLCKLMNIVIPIPAHHHLIGSGNLGLYPIVSSNKDYVHVRNVLRTMVVTILQKVEGNQLVLRKPVTGHQYAIKNTGPFPWEKGDTLTLIPPLSTHSEEKLLKLGDWELTVPLVVPTAIAAEINIRLLCIGLIAVHREYNEMQTIIDELCSIQYRDVLIKLPDIVNDKQSMYSMKTACISLSMITAMAPDIVRTYIDRLTLEDHSMLLIKCQELLSKRTTLNTQRCGQLHATEIKDELKKVKSVLTMIDQINSLTNEKTYFVVCDVSADNRMATCIYKN", "output": "Structural component of the T=16 icosahedral capsid. The capsid is composed of pentamers and hexamers of major capsid protein/MCP, which are linked together by heterotrimers called triplexes. These triplexes are formed by a single molecule of triplex protein 1/TRX1 and two copies of triplex protein 2/TRX2. Additionally, TRX1 is required for efficient transport of TRX2 to the nucleus, which is the site of capsid assembly."}]}
+{"id": "function_valid_4050", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MADDLSLGFTTVWNAVVSELNGESNTDDEATNDSTLVTPLTPQQRAWLNLVQPLTIIEGFALLSVPSSFVQNEIERHLRTPITDALSRRLGQQIQLGVRIAPPSTDHIDDNSSSADVLLTDDCGTDTDENYGEPLTGEYQGLPTYFTERPHHTESTVTGGTSLNRRYTFETFVIGASNRFAHAAALAIAEAPARAYNPLFIWGESGLGKTHLLHAAGNYAQRLFPGMRVKYVSTEEFTNDFINSLRDDRKVAFKRSYRDVDVLLVDDIQFIEGKEGIQEEFFHTFNTLHNANKQIVISSDRPPKQLATLEDRLRTRFEWGLITDVQPPELETRIAILRKKAQMERLAVPGDVLELIASSIERNIRELEGALIRVTAFASLNKTAIDKALAEIVLRDLIADASTMQISAATIMTATAEYFDTTIEELRGPGKTRALAQSRQIAMYLCRELTDLSLPKIGQAFGRDHTTVMYAQRKILSEMAERREVFDHVKELTTRIRQRSKR", "output": "Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)."}]}
+{"id": "function_valid_4051", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLNIIKSKLNTTYKKKGLNDSSIAIYNRDVIPAVRNWKSSIYAYNKNAINLIPIKSKYVMKLIKAYFNLYNLQLESLLRKNRLRRRFRKISTNRIFISDGEFKHTNDKVNITLYVYNKQKLNYLLKLKKRYLTLFKKAKFARKLKLIKNVGLNILCKHKQKSILLSNLLPKYNTQVNTAQNIYYTRFIKKSFKRLKFYMYYKQMLYINKAKFENTYLQGLINLVRNIFNKNVEFNIINLKYFYFNSKIFTQPLELKLKKKRNVLRYLKVLIRKAKIKNVKLAEKSKKFFNFNIFNSDNFLQQDNTKSKYLKKIILSNLKYKRVSGVRLEAAGRLTRRFSASRSQRRTKYKGNLENVYSSFKGYPTPVLRGNDKANLQYTVINSTSRVGAFGVKGWISST", "output": "Essential for mitochondrial protein synthesis and required for the maturation of small ribosomal subunits."}]}
+{"id": "function_valid_4052", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MVIETWKKSGIATKFPTYRNSAPVTVHSWQKGKRQDVEAEGLWRIKDGIYDFTEFIDKHPGGTFWIRETKGTDITEAFEAHHLTTAPEKMIAKYKVRDAYQRIYTLTLHEDGFYKTLKERVREKLKTIDKRPKRKSDVSDDL", "output": "May play a role in muscle cell metabolism."}]}
+{"id": "function_valid_4053", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKMLTVFDPAMCCSTGVCGSDVDQVLVNFSADVQWLKGRGVQIERYNLAHEPMSFVENEKAKAFLEASGAEGLPLLLLDGETVMAGRYPKRAELARWFGIPLEKVGLASTSCCGGKTSCC", "output": "Inducer-independent trans-acting repressor of the ars operon."}]}
+{"id": "function_valid_4054", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIHSLPSPEPFVILAMPRTGTHYLEALLNDHPNILSNGELLNSYDENWPDKDRLRHSDRELLELAYMRYPPAKKKVTHVGCKINEPQFYERPGFFDELARWQGLKVILLTRNTLESLRSLVQARQTGQWLKFSPDRNEPPSVSLSVNECEAYFKAADDFHARVKDAFDPSKLLMIEYQDLLLKPSACLAAVLAFLGAPAHRFSNRATIQRQETRSLARSLRNFVELRRHFAGGPYAKFFELDDASAPQG", "output": "Required for the formation of sulfated nod factor. Proposed to transfer activated sulfate (PAPS) to a N-acetylglucosamine of the nod factor."}]}
+{"id": "function_valid_4055", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPRKGPVAKRDVLPDPIYNSKLVTRLINKMMVDGKRGKSQAILYSAFDIIAQETGKDPMEVFEQAMKNIMPLLEVKARRVGGANYQVPIEVRADRRSTLGLRWLVNYARLRGEKTMEVRVAREIMDAANNTGASVKKREDTHKMADANRAFAHYRW", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."}]}
+{"id": "function_valid_4056", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPKKNEAPASFETALSELEHIVTRLESGDLPLEDALNEFERGVQLARQGQAKLQQAEQRVQILLSDNEEASPEPFIADNE", "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."}]}
+{"id": "function_valid_4057", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAMVQPKSQKARLFITHLLLLLFIAAIMFPLLMVVAISLRQGNFATGSLIPEQISWDHWKLALGFSVEQADGRITPPPFPVLLWLWNSVKVAGISAIGIVALSTTCAYAFARMRFPGKATLLKGMLIFQMFPAVLSLVALYALFDRLGEYIPFIGLNTHGGVIFAYLGGIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDVNSYTLAVGMQQYLNPQNYLWGDFAAAAVMSALPITIVFLLAQRWLVNGLTAGGVKG", "output": "Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane."}]}
+{"id": "function_valid_4058", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "KCCKKGGPRKCPPEGMTXFYERIFRI", "output": "Exhibits antibacterial activity. May play a role in protection against parasite settlement."}]}
+{"id": "function_valid_4059", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "GASGLIPVMRN", "output": "Mediates visceral muscle contractile activity (myotropic activity)."}]}
+{"id": "function_valid_4060", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "RQERLAKLFTEAVRRWDVSFTENLPDYMKELVSFFRKGWEDYLLGYYEEAEWLAAEYVPSLDEYIK", "output": "Involved in defensive oleoresin formation in conifers in response to insect attack or other injury. Involved in sesquiterpene (C15) olefins biosynthesis (By similarity)."}]}
+{"id": "function_valid_4061", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKSNHMQVEAICNGYVIDHIPSGQGVKILRLFSLTDTKQRVTVGFNLPSHDGTTKDLIKVENTEITKSQANQLALLAPNATVNIIENFKVTDKHSLALPKEVENVFPCPNSNCITHGEPVISSFTIKMIKGNIGLKCKYCEKTFSKEIVTAQV", "output": "Involved in allosteric regulation of aspartate carbamoyltransferase."}]}
+{"id": "function_valid_4062", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTQPVQTIDVLLAEHAELELALADPALHSNPAEARRVGRRFARLAPIVATHRKLTSARDDLETARELVASDESFAAEVAALEARVGELDAQLTDMLAPRDPHDADDIVLEVKSGEGGEESALFAADLARMYIRYAERHGWAVTVLDETTSDLGGYKDATLAIASKADTPDGVWSRMKFEGGVHRVQRVPVTESQGRVHTSAAGVLVYPEPEEVGQVQIDESDLRIDVFRSSGKGGQGVNTTDSAVRITHLPTGIVVTCQNERSQLQNKTRALQVLAARLQAMAEEQALADASADRASQIRTVDRSERIRTYNFPENRITDHRIGYKSHNLDQVLDGDLDALFDALSAADKQSRLRQS", "output": "Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA."}]}
+{"id": "function_valid_4063", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTATRLPDGFAVQVDRRVRVLGDGSALLGGSPTRLLRLAPAARGLLCDGRLKVRDEVSAELARILLDATVAHPRPPSGPSHRDVTVVIPVRNNASGLRRLVTSLRGLRVIVVDDGSACPVESDDFVGAHCDIEVLHHPHSKGPAAARNTGLAACTTDFVAFLDSDVTPRRGWLESLLGHFCDPTVALVAPRIVSLVEGENPVARYEALHSSLDLGQREAPVLPHSTVSYVPSAAIVCRSSAIRDVGGFDETMHSGEDVDLCWRLIEAGARLRYEPIALVAHDHRTQLRDWIARKAFYGGSAAPLAVRHPDKTAPLVISGGALMAWILMSIGTGLGRLASLVIAVLTGRRIARAMRCAETSFLDVLAVATRGLWAAALQLASAICRHYWPLALLAAILSRRCRRVVLIAAVVDGVVDWLRRREGADDDAEPIGPLTYLVLKRVDDLAYGAGLWYGVVRERNIGALKPQIRT", "output": "Involved in the biosynthesis of the enzyme cofactor mycofactocin (MFT). Acts as a glycosyltransferase that catalyzes the oligoglycosylation of pre-mycofactocin (PMFT), adding up to nine beta-1,4-linked glucose residues. Is required for the in vivo ethanol assimilation in M.smegmatis."}]}
+{"id": "function_valid_4064", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MATTADFKNGLVLVIDGQLWTITEFQHVKPGKGPAFVRTKLKNVLSGKVVDKTFNAGVKVDTATVDRRDTTYLYRDGSDFVFMDSQDYEQHPLPEALVGDAARFLLEGMPVQVAFHNGVPLYIELPVTVELEVTHTEPGLQGDRSSAGTKPATLQTGAQINVPLFINTGDKLKVDSRDGSYLGRVNA", "output": "Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)."}]}
+{"id": "function_valid_4065", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGIKVYKPTTNGRRNMTGSDFAEITTSTPEKSLLVSMSKTAGRNNTGRITVRHHGGGHKRKYRMIDFKRTTDNVVAKVATIEYDPNRTANIALIVYANGVKSYILAAKGLEVGMTVVSGPDADIKVGNALPLANIPVGTLIHNIELKPGKGGQLVRSAGASAQVLGSEGKYTLVRLQSGEVRMILSTCRATIGVVGNEQQSLINLGKAGRTRHMGIRPTVRGSVMNPNDHPHGGGEGRQPVGRKSPMTPWGKPALGLKTRNKKAKSSKLIVRRIND", "output": "One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome."}]}
+{"id": "function_valid_4066", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAKDDVIEVDGKVVDTMPNAMFTVELENGHQVLATISGKIRKNYIRILPGDKVQVELSPYDLTRGRITYRFK", "output": "One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex."}]}
+{"id": "function_valid_4067", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MANRLKEKFVNEITPDLVKKFDYTSVMQVPKIEKIVLNMGVGDAVTNSKNLDEAVAELELISGQKPLVTKAKKSIAGFRLREGMSIGAKVTLRGERMYDFLDKLVNVSLPRVRDFRGVSSKAFDGRGNYTLGVREQLIFPEIDFDNVNRVRGLDIVIVTTANTDEESRELLAQFGMPFEK", "output": "This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs."}]}
+{"id": "function_valid_4068", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSLNRATVAKRYSQALFDLLSEKDQLESGYTELQELRRIFQDNPQLSTMLSDASLQVADREALLQPLLKQASPYIKNLIQMVYDYGRMENMVDIIDQFQVLYDELHHTVYAEVTTAVELSAEQKSQIEAVYAKRVGAEKVVLSSKVDPDVIGGVIVKAADTILDGSLRTKINRLRQQLLA", "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "}]}
+{"id": "function_valid_4069", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSAPETTAPLQPPAAQAASLPGSLAESLASSGITELLAQLDRELIGLKPVKARIRDIAALLLVDKLRAARGFSAGAPSLHMCFTGNPGTGKTTVAMRMAQILHQLGYVRRGHLVAVTRDDLVGQYIGHTAPKTKEILKKALGGVLFIDEAYYLYRPENERDYGQEAIEILLQVMENNRDDLVVILAGYKDRMDRFFESNPGMSSRVAHHVDFPDYQLDELRQIADLMLAEMQYRFDDESRAVFADYLARRMAQPHFANARSVRNALDRARLRHASRLLDDAGTVADDRTLTTITASDLLASRVFSKAAPAAQTPAKE", "output": "Seems to be necessary for the expression of RuBisCO."}]}
+{"id": "function_valid_4070", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MYAVIKTGGKQYKVAEGESIFVEKLDVQAGEEVVFDQVILVANGDDVKVGTPLVEGAKVVASVDKQGKEKKVVTFKYKPKKHSHSKYGHRQPYTKVTVKSIEA", "output": "This protein binds to 23S rRNA in the presence of protein L20."}]}
+{"id": "function_valid_4071", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTRIKRGYIARRRRTKIRLFASSFQGARSRLTRTITQQKIRALVSAHQDRGRQKRDFRRLWITRINAVIRANKVYYSYSTLIHHLYKRQLLLNRKILAQIAILNRNCLYMISNEILK", "output": "Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit."}]}
+{"id": "function_valid_4072", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSTVPVKIKPLDHYEGLALPAYETPQSAGMDLRAAVPADEPVSIPPGEWRLIPVGIAIALPAGFEAQVRPRSGLAAKHGISCVNTPGTVDADYRGEIRVNLINHGQANFVVNRGDRIAQMIIAPVTQAVWEIADTLDETTRGTGGFGSTGTK", "output": "This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA."}]}
+{"id": "function_valid_4073", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLTLSDFDFPLPPELIAQSALPDRSASRLLVVERLAPADTADAVRMVDRAFSDIVDYLRPDDLLVFNDTRVIKARFFGHKPSGGKIEVLVERVVDSHTVLAQVRASKTPTEGSILHLADGAFAVTVGPRVDQFFTLRFPEPALDLIERYGRLPLPPYIRHDPDAYDETRYQTVYARSPGAVAAPTAGLHFDDALFARLNAAGVRRAFLTLHVGAGTFQPVRTENLAEHKMHSEWYAVSADLAQAVRDTRARGGRVIAVGTTSLRALESAAQADGTLAAGSGDTDIFITPGYRFRLVDALITNFHLPKSTLLMLVSALAGVEAIRAAYRHAVEQRYRFFSYGDAMLLTRQPGA", "output": "Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)."}]}
+{"id": "function_valid_4074", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKKIVLAGGCFWGVEEFLSRINGVVSTEVGYANGRTENPTYEDICTKNTYFAEVCLVNYDENIISLKELLAKFWTIIDPTSLNKQGNDVGSQYRTGIYYVEPSDLEEILNSKEELQKSYSKKIVTEVKPLENYYKAEEYHQKYLKKNPNGYCHIKLD", "output": "Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine."}]}
+{"id": "function_valid_4075", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSNIIKQLEQEQMKQDVPSFRPGDTVEVKVWVVEGSKKRLQAFEGVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSISVKRRGAVRKAKLYYLRERTGKAARIKERLN", "output": "This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site."}]}
+{"id": "function_valid_4076", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFAEHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTQLIERLGLRR", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.; "}]}
+{"id": "function_valid_4077", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MHRNDSQRLGKPGGAPESLQMANNNFLSTLSPEHCRPLAGECMNKLKCGAAEAEIMNLPERVGTFSAIPALGGISLPPGVIVMTALHSPAAASAAVTDSAFQIANLADCPQNNSSGAGGNPAKKKRKRCGVCVPCKRLINCGVCSSCRNRKTGHQICKFRKCEELKKKPGTSLERTPVPSAEAFRWFF", "output": "Acts as a negative regulator of the Wnt signaling pathway required for anterior neural structure formation (By similarity). Binds preferentially to DNA containing cytidine-phosphate-guanosine (CpG) dinucleotides over CpH (H=A, T, and C), hemimethylated-CpG and hemimethylated-hydroxymethyl-CpG (By similarity)."}]}
+{"id": "function_valid_4078", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTMKPVIALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGDGQLGGYLYTVVDTGGIGENDDGIDVPMTSQSLQAVGEADVVLFMVDGRAGLTAADEQIASELRKLPKPTYLIVNKTDGVDADSAMSEFFALGLTEVLPIAAAHGRGVTSMIEHILEGFTDLELLPEGEHRTSKKPGEDSIRVAVLGRPNVGKSTLINRMLGEERVVVFDHAGTTRDSIEVPFERMGRAYTLIDTAGVRRRGKVFEMVEKFSVIKALQAMEAAQVVVVVIDAREGITDQDLHLLGYALDSGRALMIAVNKWDGLEADHKERVRVNLGRRLEFAPWVKIKFISALHGTGVGDLWGMVEQAWDSAFIKIGTNELTRMMEEITNGHPPPRNGRFRAKLRYAHLGGNNPPTLVLHGNRTEALPTSYKKFLENRFRELLKLEGTPIRLEFKSGTNPYEGRKNVLTDRQVHKRKRMIKRMKK", "output": "GTPase that plays an essential role in the late steps of ribosome biogenesis."}]}
+{"id": "function_valid_4079", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "TKKDGEEKVA", "output": "Strongly inhibits trypsin and plasma enzyme(s) activity."}]}
+{"id": "function_valid_4080", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEFTLEEIAHLLGGEVKGDGKAKVSSIAKIEEASSGSISFLSNPKYESFIYSTNASAVIVKKDFQPRESLKTSLILVDDPYTSFTTILEAYQQALNASKMGKEEPSFIGKNAVIGSNHYIGAFAYIGSNCKIGNNVKIYPQAYIGDNVTIGDNTTIYAGVKIYANCELGNQVTIHSGCVIGSDGFGFAPQADGTYKTIPQIGNVVIGNHVDIGANTVIDCATMGSTIIYDGVKIDNLIQIAHNVKIGKNTVIAAQAGISGSTTIGENCIIAGQVGIIGHIKIANKTTIAAQAGIGRTISEEGLTLLGSPAIEKLDFLKSFAIYRKLPTLQKRIEELEEKTLNLSGIKES", "output": "Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell."}]}
+{"id": "function_valid_4081", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTELKLDPYFGEYGGMYVPQILVPALKQLESAFVDAQQDPAFQAEFTDLLKNYAGRPTALTLTRNLSPNPLVKIYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLGLKCKVYMGAKDVERQSPNVFRMKLMGAEVIPVTSGSATLKDACNEAMRDWSASYDKAHYLLGTAAGPHPFPTIVREFQRMIGEETKQQILEKEGRLPDAVIACVGGGSNAIGMFADFIDEPSVELIGVEPAGKGIDTPMHGAPLKHGKTGIFFGMKAPLMQDRDGQIEESYSVSAGLDFPSVGPQHAHLNAIGRARYESATDDEALAMFQQLARCEGIIPALESAHALAYAVKLAKTATKETILVVNLSGRGDKDIFTVSDILAAKEQESGND", "output": "The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine."}]}
+{"id": "function_valid_4082", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MHSSYPTITGLGLVPTVIEQSGRGERAYDIYSRLLRERIVFLVGPVNEQSASVIVAQLLFLESENPDKDISFYINSPGGSVYDGLAIYDTMQFIKPEVSTLCTGFAASMGTFLLTAGQRGKRYALPNARIMIHQPSGGSQGTAADVEIQAKEVLYLRERLNAMMAERTGRSIEEIARDTDRDNFMSAHAAKTYGLVDEVLETRAALGASPHLHDR", "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins."}]}
+{"id": "function_valid_4083", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MITNNLVPTVIEKTAGGERAFDIYSRLLKERIVFLNGEVNDHSANLVIAQLLFLESEDPDKDIYFYINSPGGMVTAGMGVYDTMQFIKPDVSTICIGLAASMGSLLLAGGAKGKRYSLPSSQIMIHQPLGGFRGQASDIEIHAKNILRIKDRLNKVLAHHTGQDLETIVKDTDRDNFMMADEAKAYGLIDHVIESREAIIK", "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins."}]}
+{"id": "function_valid_4084", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKLLLFILMISSIIIVPVGQAQRIKDLASVQGVRSNQLVGYGLVVGLPGTGEQSPFTEQSFRTMLSNFGISLDSSLKPKIKNVAAVAVHAELPPFLKPGQTIDVTVSSVGEAASLRGGTLLQTFLKGLDGKVYAVAQGSMVVSGFGAEGADGSKIVANTPTVGRIANGALIERAVPSGFMQNDFLTLNLNYPDFSTAKILADTINQRLGADPDKGYVIATPIDAASVRVSAPRDVGQRVGFLATLENFEFMPAKAPARIVINSRTGTIVIGQDVRLLPAAITHGGLTVTISENQQVTQPNPLGQGDTVVTDQSIIDVNLDDTRMFKFDPGVTLDQLVRAVNEVGAAPGDLMAILEALSEAGALQGELVVI", "output": "Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation."}]}
+{"id": "function_valid_4085", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MALNLEKKQEIIKAFATKENDTGSCEVQVALLNERIKLLTEHLKANPKDHSSRLGLLELVAQRRNLLKYIKRTDHARYVVLIEKLGIKDR", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.; "}]}
+{"id": "function_valid_4086", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLWFKNLMVYRLSREVSLSADEMEKQLSAFSFTPCGSQDMAKTGWVSPMGSHSDALTHTVNGQIVICARKEEKILPSPVIKQELQDKIERLEGEQHRKLKKTEKDSLKDEVLHSLLPRAFSRFNQTFLWIDTVNDLIMVDAASAKRAEDTLALLRKSLGSLPVVPLTLENPIELTLTEWVRSKTLPAGFALMDEAELKAILEDGGVIRCKKQDLFSDEIAVHIEAGKLVTKLALDWQERIQLVLSDDGSLKRLKFADTLRDQNEDIDREDFAQRFDADFILMTSELAALIKNLIEALGGEAQH", "output": "May be involved in recombination."}]}
+{"id": "function_valid_4087", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MANHKSAEKRIRQTIKRTERNRFYKTKVKNIIKAVREAVAINDVAKAQERLKIANKELHKFVSKGILKKNTASRKVSRLNASVKKIALA", "output": "Binds directly to 16S ribosomal RNA."}]}
+{"id": "function_valid_4088", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQGYFITFEGPDGAGKTTVINEVVKAIQGQCKREILVTREPGGSKIAEKIRDIILDPANTEMNAKTEALLYAASRSQHVSEIINPALKRGDLVMSDRFVDSSLAYQGQGRGLGIDEVAQINAFATGHLEPDLTIFLDLDPAQGLARIAKVRSGSEDRLEQEKLAFHEEVYRGYQKVNQAHPDRVKVVDASQDLPQVVAASVKLVKSTFPELF", "output": "Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis."}]}
+{"id": "function_valid_4089", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDIKLKDFEGPLDLLLHLVSQYKVDIYEVPIVEVIEQYLNYIETLQVMKLEVAGDYMLMASQLMLIKSRRLLPKVVEHIEEEDLEQDLLEKIEEYSRFKAVSQALAKQHDQRAKWYSKPKQELIFEDAILQEDKTVMDLFLAFSNIMAAKRAVLKTNHTVIERDDYKIEDMMASIKQRLEKENVISLSAIFEECQTLNEVISIFLASLELIKLHVVFVEQLSNFGAIILRKEKK", "output": "Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves."}]}
+{"id": "function_valid_4090", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAGHEVRYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSGLKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLVNKETGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGSTVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIVDIFGESDLVRNTIEKDIHKNPSDSRTDEALKEIYERLRPGEPKTADSSRSLLIARFFDARRYDLAAVGRYKVNKKLNIKTRLLNQIIAENLVDAETGEILVEAGTEMTRSVIESIEEHLDGDLNKFVYTPNDYAVVTEPVVLQKFKVVSPIDPDRVVTIVGNANPDDKVRALTPADILAEMSYFLNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQQIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVRDVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRATGRVTNEIVWLTADEEDEYTVAQANSKLNEDGTFAEEIVMGRHQGNNQEFSASVVDFVDVSPKQVVAVATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQHNGKVVFSDAEKVEIRRQDGSLDVYHITKFRRSNSGTAYNQRTLVKVGDIVEKGDFIADGPSMENGEMALGQNPVVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDTKLGPEEITREIPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERLLHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRKIKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHLGMAARNLGIHIATPVFDGASSEDLWDTVREAGMDSDAKTVLYDGRTGEPFDNRVSVGVMYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVLQEILTYKSDDVTGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDNEVELRDLDEGEDDDIMHVDDLEKAREKQAQETQEVSETTDEK", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_valid_4091", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "METATLVAIFISGLLVSFTGYALYTAFGQPSQQLRDPFEEHGD", "output": "May play a role in photosystem I and II biogenesis."}]}
+{"id": "function_valid_4092", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRDPVETYMNLVPMVVEQTNRGERAYDIFSRLLKERIIFVTGPVEDNMSMLVVAQLLFLEADNPKKEISMYINSPGGVVTSGLAIYDTMQFIRPPVATLCTGQAASMGSLLLAAGEKDMRHALPNARIMVHQPSGGFQGQATDIMLHAQEILNLKKRLNEIYVKHTGQTYKAIEDALERDKFLTADMARDFGLVDKVIDKRAEEPAAPKAS", "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins."}]}
+{"id": "function_valid_4093", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKICLIDETGAGDGALSVLAARWGLEHDEDNLMALVLTPEHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALSDITPRPQVVCLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVKRPDYAPPLANVATPNAVVTKGHRFDIYAGTPV", "output": "Specifically methylates the guanosine in position 1516 of 16S rRNA."}]}
+{"id": "function_valid_4094", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTTNTVSRKVAWLRVVTLAVAAFIFNTTEFVPVGLLSDIAHSFHMQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLSFLSWSFTVLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGLPLGRIVGQYFGWRMTFFAIGIGALITLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSIYLLTVVVVTAHYTAYSYIEPFVQNIAGFSANFATALLLLLGGAGIIGSVIFGKLGNQYASALVSTAIALLLVCLALLLPAANSEIHLGVLSIFWGIAMMIIGLGMQVKVLALAPDATDVAMALFSGIFNIGIGAGALVGNQVSLHWSMSMIGYVGAVPAFAALIWSIIIFRRWPVTLEEQTQ", "output": "Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites."}]}
+{"id": "function_valid_4095", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGQSKKLNKQPNSLSPLVQLAGIRKCFDGKEVIPQLDLTINNGEFLTLLGPSGCGKTTVLRLIAGLETVDSGRIMLDNEDITHVPAENRYVNTVFQSYALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLETFAQRKPHQLSGGQQQRVAIARAVVNKPRLLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPKNLFVAGFIGEINMFNATVIERLDEQRVRANVEGRECNIYVNFAVEPGQKLHVLLRPEDLRVEEINDDNHAEGLIGYVRERNYKGMTLESVVELENGKMVMVSEFFNEDDPDFDHSLDQKMAINWVESWEVVLADEEHK", "output": "Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system."}]}
+{"id": "function_valid_4096", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRSGVFVAVLVVVVFALLTQGQELHVPEREAVANLAARILKIVHAPHDAAAGVPHKRNSELINSLLGISALMNEAGRR", "output": "The pigment-dispersing hormone causes the migration of the distal retinal pigment into the proximal end of the pigment chromatophore cells and thus decreases the amount of light entering the retinulas. May also function as a neurotransmitter and/or neuromodulator (By similarity)."}]}
+{"id": "function_valid_4097", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSRIGKRPISIPGGVDVNIEGNVVTVKGPKGTLTKEMHSLINIAVEEQQIVVTRPDDQPLSRSLHGLTRTLVANMVEGVTKGFSKSLDMVGVGYRAAKQGNKLVLSVGKSHPVELIPFEGIEVEVPAQNKIIVKGMDKELVGDFAAEIRKERPPEPYKGKGIKYENEVVRRKAGKTGAKKGGKK", "output": "This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center."}]}
+{"id": "function_valid_4098", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKIQDYTKQMVDEKSFIDMAYTLLNDKGETMNLYDIIDEFRALGDYEYEEIENRVVQFYTDLNTDGRFLNVGENLWGLRDWYSVDDIEEKIAPTIQKFDILDADDEEDQNLKLLGEDEMDDDDDIPAQTDDQEELNDPEDEQVEEEINHSDIVIEEDEDELDEDEEVFEDEEDFND", "output": "Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling."}]}
+{"id": "function_valid_4099", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDYDSMKEQWGEVEDRDGVRLSWNVFPSTRMEASRLVVPIGALYTPLKEKPDTPLLQFEPVTCKQPCRSVLNPFCQVDVRARLWICPFCLSRNPLPPHYKDITAQAIPPELHPSNTTIEYRLSRPAPSPPIFLYVVDTCQEEDSLAALKESLIMSLSLLPENALVGLITYGTMAQVHEIGYTECAKSYVFRGSKEYAAKQVQEMLGLIQPAMRPGMPAHQPGRPMPMGPASRFLLPVTQAEFQLTKALEQLQQDPWPISSDRRNLRCTGVALSVAVGLLETSFQNAGGRIMLFAGGPATEGPGMVVGPELREPIRSHHDIDRDNVKYYKKALKFYDNLAKRTAHNGHTIDIFAGCLDQVGLLEMKGLCNSTGGHMILTDSFTSSMFKQSFIRVFEKDGDDNLLMGFNAVLEVLTTKELKVTGLIGHAVSLNKKSTSVGETECGIGNTCSWKMCGIDPKASYGVYFEIAQGGPSQHQQNQKGMIQFLTYYQHSSGQFHLRVTTIARDLSGPAGDPAIAHSFDQEAAAVLMSRIAVFKAEVDDGPDVLRWVDRMLIRLCSRFADYRKDDPSSFRLEKNFTLYPQFMFHLRRSQFLQVFNNSPDETAFYRHVLDHEDVSNSLVMIQPTLDSYTFDQEGGQPVLLDSSSIQPTHILLLDTFFHILIFHGETVAEWRKAGYQDQEGYENFASLLEQPKEDARDLITDRFPLPRFIVCDHGGSQARFLLSKLNPSTTHTSGAGAYGGVGAQSAQTIFTDDVSLQTFMEHLMKLAVSGTN", "output": "Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity)."}]}
+{"id": "function_valid_4100", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEDVGVNNDTVHPEARAYITSLVSALGGYGVDDDGGYTLGDDALEVLRDLKRWVRFYDERTNRMDVARCLAESNLVTSDLLQIMAKWVSNESSSKYMERIAFACLEIMVPLTWPIERDSETMTVNHHRHLPVLQLAQLGYKRAIINFDVAPILSTAVRIALPCMAIPNGDRSSRDQATIKLILYFLRNIAMIAPPPGLKYEGDETQVSRSTLIDAFTFQDIFLTILTIASNMGEDFRTEDVIILDIIFHIVKRVDSSKLFVSEKRLHKIKEDELTAAMRKEAAMLKSYNKNAPTRHSRFGTMIWVKRESGKLATVSGQDALLDAATRERKMDSNKSFKPPRRARKEDMEPKDLGPRVSLDERARRQLQSFVSEFLDSGFNPLFSHVRRSLDREAPHVLQSHHSQFFYLVAWFLEAERMRKKAAKDSKNQTSTGEDVGSFNLVAEVLNQEMFITMSRTLDRAYGDKDWRLLTTVMRCFTQILLTIQEMASSGNEENEEIADNILSRLFYEETTHDLIANIVRTYKDQGFEYLDACTELTHTFVRILEAYSKENVDLQVRSRKRTRRKKKAAKAAGDQGDDEGQGDAEDDSADDERQAEKTSQERKFDFKRFALRFAPQGVVDTFVTFTKYYRDLDDSQLKRAHRYFFKLAFKQDMSVMLFRLDIIHLFYNMIKGPEPLDKSSSMYKEWEDLAMQTIRKCVKKLEERPALFTELLFSKITSTAHYLEYGHEKQTISNPRPAAELEFKREVEREQQIAILVGVLIDRSQTDHLGWIKKQLSDAESERRAWENAERALAAERPDDEVMAGSAEAIAAKTPDHVTMRPDTDARRTAMFKNPHLRLLMKLVGLERLAPTLDETPDAIWIIPGTLTADALKETISLINKAEFTPPIFDDGELAEDQLRRKTAPRKRAAYDDDDNLDGINDLINDGSDDDGDDGTGILFPAGGPTARKRTAQDEPPKKRLQRRRRRGGSDDPDADTAETDAQAEARARARRKKELEKARKIKSEMYVDPREDDSDYEGNKERDRLFFAREEERQAVKDATFGLSSRPEGVGEGAWEALVGAVMGGGDGDDGEGEDAVVGERPPKVGGRKRKSGVADLAESGGEDSEEGDEDDESRSEEDGSAVSEAEAPAAAGRRPNKRRKPAQKKKKRVVDISSGEDDDVGMDMDVDVDADADADAMDFTQSSKDGAVTNDTPLSSDPSRTTKPGGAEGSGDKGGGEDEDEDMPVAKPVARARPRARAGFIVESSDEE", "output": "Forms a fork protection complex (FPC) with CSM3 and which is required for chromosome segregation during meiosis and DNA damage repair. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity)."}]}
+{"id": "function_valid_4101", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLEDRRLEVLRAIVEDFVLSNEPVGSKALAERHNLGVSPATVRNDMSALEEEGYITQPHTSAGRIPTDKGYRLFVDRLSGVKPLSRAERRAIQSFLEGAVDLDDVVRRSVRLLAQLTRQVAVVQYPSLSSSSIRHIEVVTLGPYRLLMVLITDTGRVEQRIVDSLVPVDDEVAGELRSVLNCALAGRRLVDAPDIVAALPDSTRSELRPYLTTVAGAVLESLVERQEERIAMAGTANLTRSPVDFADSLRSILEALEEQVVLMKLIGSARETGTVTVRIGRETDVDALRSTAVVATGYGRGPFALGGMGVLGPMRMDYPGTMAAVRAVAKYVGELLGAD", "output": "Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons."}]}
+{"id": "function_valid_4102", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTARMDKRFAELKAEGRPALVTYFMGGDPDYDTSLGIMKALPEAGSDIIELGMPFSDPMADGPAIQLAGQRALKGGQTLKKTLQLAADFRKTNDLTPIVMMGYYNPIYIYGVEKFLDDALAAGIDGLIVVDLPPEMDDELCIPAIRKGINFIRLATPTTDEKRLPTVLKNTSGFVYYVSMNGITGSALPDPSLVSGAVQRIKQHTELPVCVGFGVKTAEHAKVIGGSADGVVVGTAIVNQVATSLTKDGKATPDTVQAVATLVRGLSSGARSARLVAAE", "output": "The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate."}]}
+{"id": "function_valid_4103", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKEFWQTCVSRLEQELPPQQISAWIRPLVPLAYDEAQAVLRVAAPNRFKLDWVRKNFSHQIEALAAEWYQRPVQVQFELPSHSTTPRIPVTPRAAVAPVAPASAAPLAPAAPPVAAAYSAPPEPPAAPAQTSAAVDAANIVYERSRLNTDLTFENFVTGKANQLARAAALQVAENPGTSYNPLFLYGGVGLGKTHLIHAIGNAMVAAGTGVRVRYVHADQYVSDVVKAYQRKAFDDFKRYYHSLDLLLIDDIQFFSGKNRTQEEFFYAFEAMVAQRKQIIITSDTYPKELSGIDSRLISRFDSGLTVAIEPPELEMRVAILLRKAESEGVPMPEEVAFFIAKHLRSNVRELEGALRKVLAYARFHGREALNVDVCKEALKDLLSVSNGQITVENIQKTVADFYKIKVADMYSKRRPANIALPRQVAMYLAKELTQKSLPEIGDLFGGRDHTTVLHAVRKISDARAKQAELNHTLHVLEQTLKG", "output": "Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids."}]}
+{"id": "function_valid_4104", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MHISKPAGPLPASVPFYRQLYFQVVVAIILGALLGRFEPAFAESLKPLGDAFIKLVKMIIAPVIFLTIVTGIAGMTHLKTVGRVFGKAMVYFLFFSTLALVVGLVVAHVVQPGAGMNINPADLDQSAVKSYVEKSHDLTLVGFLMDIIPNSLIGAFTGDQVVNGKLTGPNILQVLFVAVLFGVSLALVGERGKPVLNLLEALIAPVFKLVHILMRAAPIGAFGAIAFTIGKYGVESLVNLAWLVGSFYLTSLLFVLVILGVVCRLCGFSVLKLIRYLKAELLLVLGTSSSESALPSLMEKMEKAGCEKSVVGLVVPTGYSFNLDGTNIYMTLAALFIAQATNTELTLGHQIALLAVAMLSSKGAAGVTGAGFITLAATLAVVPEVPVAGMALILGVDRFMSECRSLTNFIGNAVATVVVSRWENALDRDRLTLVLDGGEPPLLAPVGEPGVAPAALR", "output": "Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane."}]}
+{"id": "function_valid_4105", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MADLEEQLSDEEKVRIAAKFIIHAPPGEFNEVFNDVRLLLNNDNLLREGAAHAFAQYNLDQFTPVKIEGYEDQVLITEHGDLGNGKFLDPKNRICFKFDHLRKEATDPRSCEVENAIESWRTSVETALRAYVKEHYPNGVCTVYGKKIDGQQTIIACIESHQFQAKNFWNGRWRSEWKFTITPSTTQVVGILKIQVHYYEDGNVQLVSHKDIQDSLTVSNEVQTAKEFIKIVEAAENEYQTAISENYQTMSDTTFKALRRQLPVTRTKIDWNKILSYKIGKEMQNA", "output": "F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity)."}]}
+{"id": "function_valid_4106", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNHNVIIVIALIIVVISMLAMLIRVVLGPSLADRVVALDAIGLQLMAVIALFSILLNIKYMIVVIMMIGILAFLGTAVFSKFMDKGKVIEHDQNHTD", "output": "Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion."}]}
+{"id": "function_valid_4107", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDRQQQLRRLQGGLIVSCQAPADSPLHQPEIIAAIAVAAVQRGAVGIRLDTPEHVRAVRDRLPETPIIGLWKRTFPDSSVYITPRYVEAEAIAAAGADIVALDCTLRPRPDGEDFCQIIPRLQQELGCAVMADIDTLEAAIAAAKAGADLVGTTLYGYTEATQGQTPPGWDLLETAAQQLPNTPVICEGGIASAQAARQACDRGAFAVVVGTAITGIDLQVQAYVTALNARP", "output": "Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)."}]}
+{"id": "function_valid_4108", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAQQSPYSAAMAEQRHQEWLRFVDLLKNAYQNDLHLPLLNLMLTPDEREALGTRVRIVEELLRGEMSQRELKNELGAGIATITRGSNSLKAAPVELRQWLEEVLLKSD", "output": "This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region."}]}
+{"id": "function_valid_4109", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGGLSIWHWLIVLLIVALVFGTKKLRNIGNDLGSAVKGFKDGMKEGEAPADAQQLPRSGSVDVNAKETTRSDSNKA", "output": "Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system."}]}
+{"id": "function_valid_4110", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSRRHAAEKREILPDAKFGDTVLTKFMNNLMIDGKKSVAESIVYNALDRVQTRLKREPLEAFHEALDNVKPSVEVRSRRVGGATYQVPVEVRTERREALAIRWLITAARKRNENTMEERLAAELADACNNRGTAVKKREDTHKMADANKAFSHYRW", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."}]}
+{"id": "function_valid_4111", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTMHNSVEFQDAFDVIVVGAGHSGCEAALATARLGCRTLLLTLNLDKIAWQPCNPAVGGPAKSQLTHEVDALGGEIGKMADRTYLQKRILNSSRGPAVWALRAQTDKREYAAIMKNIVENQENLSIRESMVTDLVLGANDEVIGVETYFGVAFQCKAVILTTGTFLGGKIWVGNKSMPAGRAGEFAAEGLTETLNRLGFETGRLKTGTPARVDKRSVDYSKMQLQPGDEEVRWFSFDPDVWVEREQLPCHMTRTTPETHRLIRENLHLSPVYGGWVEAKGPRYCPSIEDKIVRFVDKESHQIFIEPEGRDIPELYIQGFSTGLPENLQLQMLRSLPGLENCVMLRPAYAVEYDYLPATQCYPTLMTKKVAGLFCAGQVNGTTGYEEAAAQGIVAGINAARFVRDQEMIVFPREQSYLGTLVDDLCTKDLREPYRMLTSRSEYRLLLRSDNSDQRLTPLGREIGLIDDRRWQLFTRKQEQITGEKERLYATRVKENDEVGKAIASNTQQAIKGSITLADLLRRPGFHYVDLDRYGLGNPELTPAEREGAEIDIKYSGYLARQQSQIEQIARQAQRQLPRDLDYTTVETLSKEAREKLNKVKPMTIGQAARIGGVNPADINALLIYLELRQTKHQTGLAALP", "output": "NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34."}]}
+{"id": "function_valid_4112", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAKFDPRNLPDLVRRPILTEKATIMMEQDKYTFEVTPKATKPQIRAAIEDLFQVKVVKVNTALPPRRKKRVGKFIGFKPQYKKAIVTIAPGDVEKIRQVLFPEV", "output": "One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome."}]}
+{"id": "function_valid_4113", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDMATSGRAGGRHGPAAIRQVSTNLAWEHNRFPWNFDMRERLNVVDCGDLVYAFGDAREMSEKLQAHAEKLLAAGKRMLTFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCEFDHGTMFYTAPKEGLIDPNHSVQIGIRTEFDKDNGFTVLDACQVNDRSVDDVIAQVKQIVGDMPVYLTFDIDCLDPAFAPGTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVAPAYDQSEITALAAATLALEMLYIQAAKKGE", "output": "Catalyzes the formation of putrescine from agmatine."}]}
+{"id": "function_valid_4114", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQPNDITFFQRFQDDILAGRKTITIRDESESHFKTGDVLRVGRFEDDGYFCTIEVTATSTVTLDTLTEKHAEQENMTLTELIKVIADIYPGQTQFYVIEFKCL", "output": "Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C)."}]}
+{"id": "function_valid_4115", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MYAVVKTGGKQYKVAAGEKLKVEQIPADIGAEITLDQVLAVGAGDQIKFGTPLVSGASVKATVISQGRHDKVKIFKMRRRKHYQKRQGHRQNYTELRIEAINA", "output": "This protein binds to 23S rRNA in the presence of protein L20."}]}
+{"id": "function_valid_4116", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSRVAKAPVTLPNGVSVTLNDRQVEVKGKNGNMSLRLHELVELKQEDDLIIFSPTVDSKEAMMHAGTMRSLLNNLVIGVNEGFEKRLLLIGVGYRAQATGNKVTLNVGYSHPVEYTLPEGVSAETPTQTEIVLKSNDKQQLGQAAANIRGFRPPEPYKGKGIRYSDEHVIRKEAKKK", "output": "This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center."}]}
+{"id": "function_valid_4117", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNEAVIDPILETAVNTGDMFCSQTIPNRCLKDTILIEVQPECADTLQCVLDDKVSRHQPLLLRNHKKLELPSEKSVTRGGFYMQQLELLVKSAPPNEYALLLIQCKDTALADEDNFFVANGVIDAGYRGVISALLYYRPGVTVILPGHLTIYLFPVKLRQSRLLPKNVLKHLDPIFKSIQVQPLSNSPSNYEKPVISEFADISTVQQGQPLHRDSAEYHIDVPLTYKHIINPKRQEDAGYDICVPYNLYLKRNEFIKIVLPIIRDWDLQHPSINAYIFGRSSKSRSGIIVCPTAWPAGEHCKFYVYNLTGDDIRIKTGDRLAQVLLIDHNTQIHLKHNVLSNIAFPYAIRGKCGIPGVQWYFTKTLDLIATPSERGTRGFGSTDKETNDVDFLLKH", "output": "Involved in nucleotide metabolism: produces dUMP, the immediate precursor of thymidine nucleotides and decreases the intracellular concentration of dUTP to avoid uracil incorporation into viral DNA."}]}
+{"id": "function_valid_4118", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDPVKAQQLAAELEVEMMADMYNSLLRMTGACHKKCVPPHYKEAELSKGESVCLDRCVSKYLDIHERMGKKLTELSLQDEELMKKMQQGVTST", "output": "Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity)."}]}
+{"id": "function_valid_4119", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MDPTTLVWGTESTTMNGNDQALPLLCGKETLILVVLILFIALVGLVGNAFVLWLLGFRMRRNAFSVYVLSLAGADFLFLCFPMINCLAYLINFFHSISINFPSFFTTVMTCAYLAGLSMLSAISTERCLSVLWPIWYRSRRPRHLSAVMCVLLWALSLLLSILEGKFCGFLFSDGDSGWCQTFDFITAAWLMFLFVVLCGSSLALLVRILCGSRGLPLTRLYLTILLTVLIFLLCGLPFGIQWFLILWIWKNSDVLFCHIHPVSVVLSSFNSSANPIIYFFVGSFRKQWRLRQPVLKLALQRALQDTAEVDHSEGCFSQGTLEMSGSSLV", "output": "Mast cell-specific receptor for basic secretagogues, i.e. cationic amphiphilic drugs, as well as endo- or exogenous peptides, consisting of a basic head group and a hydrophobic core. Recognizes and binds small molecules containing a cyclized tetrahydroisoquinoline (THIQ), such as non-steroidal neuromuscular blocking drugs (NMBDs), including tubocurarine and atracurium. In response to these compounds, mediates pseudo-allergic reactions characterized by histamine release, inflammation and airway contraction."}]}
+{"id": "function_valid_4120", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAEERPGAWFGFGFCGFGQELGSGRGHQVHSPSPLRAGVDVCRVSASWSYTAFVTRGGRVELSGSASGAAGGCRDAWASEGLLLVLRAGPGPEALLQAWAPDSALRGEPLWAHSVVPEAVEEDDPGGEAQIGRLPLLPCARAYVSPRPPFYRPLAPELRARQLELGAEHALLLDAAGQVFSWGGGRHGQLGHGTLEAELEPRLLEALQGLTMAEVAAGGWHSVCVSETGDIYIWGWNESGQLALPTRNLAEDGETVAREATGLNEDGSQVKRTGRVEDGAPAPFIAVQPFPALLDLPLGSDAVKVSCGSRHTAVVTRTGELYTWGWGKYGQLGHEDTTSLDWPRRVEYFVDKQLQVKAVTCGPWNTYVYAVEKGKS", "output": "Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8. Possibly together with KDM8, is involved in proper mitotic spindle organization and chromosome segregation. Plays a role in regulating alpha-tubulin deacetylation and cytoskeletal microtubule stability, thereby promoting cell migration and TGF-beta-induced epithelial to mesenchymal transition (EMT), potentially through the inhibition of KDM8."}]}
+{"id": "function_valid_4121", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKTYSAKPSEIEKKWWVIDAKNIVLGRLASRVANMLRGKHKPSFTPHLDCGDNIIIINAEHVKLTGKKANPKDGKIYYRHTGFPGGLKDTTAGKILSSKHPERVIKMAVKRMITRNTLGAKQMSNLYVYANGDHPHMAQQPTVYDFASQNPKNKK", "output": "This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly."}]}
+{"id": "function_valid_4122", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAKEIDINKLLAQENNALNTILSQVNELCEQNKKLQGLIEIQNETKELEKEHNRSLPWFKRLVKTVSNVKYIFVKSEEQLTNEAIKYNNKILKDIDNKIYNIAEKSAPLKQELQEEIEKNFKDLTKKDLSKEQRERLSEVYFSYKSKPERFSALNMTNPLQFIKAEELEKQYNSLNATKQNIQNLISENSNIKELKEIQKQVAEIREEIPYTFFEKLNNIWQNVKNVFVNNSEQVLAKNKESNTRAIRKIDEQLYKTKHKFEELIENKERNINDIIAKLPDNEELQKIVSNLANHMTSKKEPILTTSSIAKPLENNVTPPPPLTKNNIPPPPPPPPLSKNNILPPPPPPMPTMAPAQTETLSKPVGVTTTVKKLENQPRPSIDTSDLMREIAGPKNLRKVEKTDVKTQDSRDLLLQSIRGEHKLRKVEFDPNTGKPVAHSHSKPAQNVSKPNGVASILARRVAMEMSDSSSSSGSESDSGNWSDASVNSNKPKALKTRGERDAKTTTHAQKILSNRSSQKPSFVRS", "output": "Recruits and activates the Arp2/3 complex, which in turn leads to actin polymerization, promoting Rickettsia motility during infection."}]}
+{"id": "function_valid_4123", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSDDTPHPEWQLVPQGNFVRLSLTLPTVTTAPDSPSLVFSHQQLEQSLGNYLRIMAGRWQDQTLVRLAVNNQLLDARQLQAIAAGLKEQNLTLQWVETNRRQTAVAAASAGLSVDQTMADKPLVDPSETPSLPKPLVVRHTLRSGGEIRHGGDVVIIGDVNPGSSIVADGDILIWGCLRGMAHAGAKGNDQAVIMILRLAACQIRIGDRLARVGADAVDRREPEIAYITSEGIRLTPVRQFQRSALL", "output": "Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)."}]}
+{"id": "function_valid_4124", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MMKKIDVKILDPRVGQQFPLPTYATSGSAGLDLRACLDDAVELAPGATTLVPTGLAIHIADPSLAAVMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMVSIWNRGQDSFTIEPGERIAQMVFVPVVQAEFNLVEAFDATERGEGGFGHSGRK", "output": "This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA."}]}
+{"id": "function_valid_4125", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MYGWINIDKPCGISSASVVSRVKKILNVKKVGYAGTLDPLASGILPIAIGEATKLMPYAVDVQKSYIFTVQWGEQRTTDDASGEIIKKSNIVPHFEEINKIIPNFIGMIEQVPPNFSAIHVDGVRAFKLARNGQEFELSSRYVNVVRLKLLSFSRENNTADFYLLCKKGVYVRSIARDLGIRLGCFGYVAKLRRVRVGYFKQKNAITLDKLKILHNNGDTHKYLLPLWYVLQDIKHLDDVFCSVEISKIKNGQNIQLNNLYMVKNCDMCYVSTHSVPVAICSIANNVIKPVRVFNV", "output": "Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs."}]}
+{"id": "function_valid_4126", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEIILFLTMMVMITYVFSGYLYRVALVQSSRVDLIFTRFENMCFKIIGTDLEHMSAKTYVKHFLAFNGFMGFITFVLLIVQQWLFLNPNHNLNQSIDLAFNTAISFLTNSNLQHYNGESDVTYLTQMIVMTYLMFTSSASGYAVCIAMLRRLTGLTNIIGNFYQDIVRFIVRVLLPLSCLISILLMTQGVPQTLHANLMIRTLSGHIQHIAFGPIASLESIKHLGTNGGGFLAGNSATPFENPNIWSNFIEMGSMMLLPMSMLFLFGRMLSRHGKRVHRHALILFVAMFFIFIAILTLTMWSEYRGNPILANLGIYGPNMEGKEVRFGAGLSALFTVITTAFTTGSVNNMHDSLTPIGGLGPMVLMMLNVVFGGEGVGLMNLLIFVLLTVFICSLMVGKTPEYLNMPIGAREMKCIVLVFLIHPILILVFSALAFMIPGASESITNPSFHGISQVMYEMTSAAANNGSGFEGLKDDTTFWNISTGIIMLLSRYIPIILQLMIASSLVNKKSYHQDKYTIAIDKPYFGVSLIVFIVLLSGLTFIPVLLLGPIGEFLTLK", "output": "Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel."}]}
+{"id": "function_valid_4127", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAKKESFFKGVKSEMEKTSWPTKEELFKYTVIVVSTVIFFLVFFYALDLGITALKNLLFR", "output": "Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation."}]}
+{"id": "function_valid_4128", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTLDLIKIRRDLHQIPEIGLEEFKTQAYLLERIAEMTEGKDFVEQRTWRTGILVFLHGSAPEKTIGWRTDIDGLPIVEETGLDFKSIHEGRMHACGHDIHMTTALGLLDQMLQVQPKNNMLFLFQPAEENEAGGMLMYEDGAFGDWLPDEFYGLHVRPDFKVGDIATNTNTLFAGTCEVLVTFKGKGGHAAFPHEANDALVAASYFITQVQTIVSRNVDPIQGGVVTFGSFHAGTTNNVIAETAEVYGTIRTLTQEMSLLIQKRVRQIAEGVAASFGMEVDIMLKQGGYLPVENNPALAKELMAFFDASPAVNLIDCLPAMTGEDFGYLLSKVPGVMFWLGIDTPYALHHPKMSPNEEALAFAVSEIGKFLKYKAED", "output": "Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate."}]}
+{"id": "function_valid_4129", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTEKLLQMMQEKGYFNQHKKVLVAVSGGADSMSLLHFLYNHQKDLDIQLGIAHVNHKQRQESEYEENYLRHWAKEHKVPFHYSAFSGKFSENAARTFRYDFFKRIMKEADYSALVTAHHADDQAETIFMRLLRGSRLRHLSGICDVRSFGTGQIIRPFLHIPKDQLPVTFHFEDRSNSSLAYLRNRIRLTYLPTLSQENPKFKEHLCLLADEIALMDKALEELTKDITITDLSVFQQQTDAVQHLLIQSYLESFPDLQLSKGQFNQLMSFLRKKTSGKMPLKNGYVLVKTQTDFLITKEEPISLSSPSLLEFGKSIVFEEYLLTFSEPHVVSNVDTINIWSDAPIVIRHRHEGDRIDLGTHHKKIRRLFIDNKISEKDRQKAIIGEQDGQIIFLYVAGRLYLKKRPKNAILYGTVVIYKKF", "output": "Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine."}]}
+{"id": "function_valid_4130", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAQPGTLNLNNEVVKMRKEVKRIRVLVIRKLVRSVGRLKSKKGTEDALLKNQRRAQRLLEEIHAMKELKPDMVTKSALGDDINFEKICKKPDSTATERAIARLAVHPLLKKKIDVLKAAVQAFKEARQNVTEVESSKNASEDNHSKNTLYSNDNGSNLQREGTVISEQEVKETKILAKKPIHNSKEKIAKMEHGPKAVTIANSPSKPSEKDSVISLESQKTPADPKLKTLSQTKKNKESDSSLSGNSDGGEELCEEEKEYFDDSTEERFYKQSSMSEDSDSGDDFFIGKVRRTRKKESSCHSSVKEQKRLEKVFLKEDTGETHGDTRNDKTKPSTETRKLESVFFHSLSGSKSSRRNFKEQAPKTRSLDFPQNEPQFKNQFNKKLSRRLENTKQQLQLPLHPSWEASRRRKEQQSNIAVFQGKKITFDD", "output": "May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells (By similarity)."}]}
+{"id": "function_valid_4131", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKPFTELNGRVAPLDRANVDTDAIIPKQFLKSIKRSGFGPNLFDEWRYTDHGEPGQDCVNRPKNPDFVLNQPRYEGAQILLTRDNFGCGSSREHAPWALEDYGFRVLIGSSFADIFFNNCFKNGLLPIVLPAPEIDELFRQCEATDGYRLKVDLATQTIVRPDGKTIAFEVDPFRKECLLNGWDDIGLTLRHADRIRTFEEKRRADHPYYFVA", "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."}]}
+{"id": "function_valid_4132", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MHSEAEESKEVATDVFNSKNLAVQAQKKILGKMVSKSIATTLIDDTSSEVLDELYRVTREYTQNKKEAEKIIKNLIKTVIKLAILYRNNQFNQDELALMEKFKKKVHQLAMTVVSFHQVDYTFDRNVLSRLLNECREMLHQIIRRHLTAKSHGRVNNVFDHFSDCDFLAALYNPFGNFKPHLQKLCDGINKMLDEENI", "output": "Acts as a negative mediator of apoptosis. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation (By similarity)."}]}
+{"id": "function_valid_4133", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQDVETYLSTAPVLATLWFGFLAGLLIEINRFFPDALVFPSL", "output": "May help in the organization of the PsaE and PsaF subunits."}]}
+{"id": "function_valid_4134", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVALESAHLVGAGGALGALCRHYLAGAIQRETFPLGTLTVNAFGSFALGLLTFAGVTGDAALLVGVGACGSFTTFSSFSVETVRLWENGYVALAALNAVGNLACALVGIGLAWGIVRIV", "output": "Important for reducing fluoride concentration in the cell, thus reducing its toxicity."}]}
+{"id": "function_valid_4135", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRHYEIMFLVHPDQSEQVPGMVERYEGIITKHNGKIHRKEDLGRRQLAYSINKVHKAHYILMNVECNLDALNEIKNAFKFNDAILRHLITVQKQAITTESVLMKKEKETKVA", "output": "Binds together with S18 to 16S ribosomal RNA."}]}
+{"id": "function_valid_4136", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTENHYLLLTPGPLTTTKTVKEVMLYDWCTWDVEYNTMVQKVRAKLVSLATKEEEKYTTVLMQGSGTFSVEAVIGSVIPKNGKLLVCTNGAYGKRIVQMAEMLHIDVVVSQTEEWEPTNIVEVEKILQQDKEITHIAVVHCETTTGIINPIVDVCKLGKQYGKVTLVDAMSSFGGIEIDIAELQIDFLISSANKCIQGVPGFGFVIAKRDELLKCKGQARSLSLDLYDQWETMENQNGKWRFTSPTHVVHAFYQALLELEKEGGVRARYNRYYNNQKLLVNRMGEIGFKPIVNEKYQSPIITSFIYPEGNFEFQQLYNELKRYGFVIYPGKISKVDTFRIGNIGDVHEEDINRLVDSIAKGVVIG", "output": "Involved in phosphonate degradation."}]}
+{"id": "function_valid_4137", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGKKRNKVSVIGAGFTGATTAFLTAQKELADVVLVDIPQLENPTKGKALDMLEASPVQGFDANITGTANYEDTAGSDIVVITAGIARKPGMSRDDLVATNEKIMRSVTKEVVKYSPDCIIIVLTNPVDAMTYAVYKESGFPKERVIGQSGILDTARFRTFVAQELNLSVKDITGFVLGGHGDDMVPLVRYSYAGGIPLETLLPKDRIDAIVERTRKGGGEIVNLLGNGSAYYAPAASLTEMVEAILKDQRRVLPTIAYLEGEYGYEGIYLGVPTIIGGNGLEQIIELELTETEKSQLDKSVESVKNVMKVLS", "output": "Catalyzes the reversible oxidation of malate to oxaloacetate."}]}
+{"id": "function_valid_4138", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MALNIEEIIASVKEATVLELNDLVKAIEEEFGVTAAAPVAVAGGAAAGGAAEEKTEFDLVLAGAGDQKIKVIKVVREITGLGLKEAKELVDNTPKPLKEGIAKEEAEELKAKLEEVGASVEVK", "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation."}]}
+{"id": "function_valid_4139", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MFSGVVMAWQKAQGCLKESLSKDVYSLWIAPLESVRQENGVVSLAGPDRYFIAFVKQNYLKEIERSLTGVDSSITDVRFLEKKAVPQLRSMMHRTSTSAPTFPVPSVSSASTASTASTASSASSVPRQLRLPSVPKNNASIRALHPRYTFDEFMVGQSNILAESACRAISADADTVGPCLYINSGTGLGKSHLTHAVAHHLLSNSPMTRMHYVTAQQFSAEMVHGIKNNSMDMFKKKYQEDCDILLVEDIHTLKGKKKTQEELNEVLDTLVKSGKRVLLTANAAPRELAGIDGEFRSRMSAGLITSIQAPDIKTRSRIVERKAAGQRLSFDEDMTSYLAQNVRGDVRQIESAITAIGARARLMGGYIDMNLIREVVGSVVGCNQSLSSSLIRDLISAQFQVSVEDLQSRSRKKSISLPRQIAMYLSRKFTEESLAEIGRTYKRDHSTVIHSVKVITDKARRDMSLGAQVNLLSDKVKQI", "output": "Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids."}]}
+{"id": "function_valid_4140", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTSNTLHYTVEKSSILGPEWQSLYSTAEPVDFDKSHFEQAMLNVIRQPNVNSTVILRADMLIDNEYDLESGSCVKSEKKDIALGSDEGILKVNIDDLAPRSVPIALADVTTKFQFVRRIVPRNPFKDAIINQTCLVMNSNSDASTSLVIYIPHFDNAELCPFYIPQVAAVGILLHDHQLSVHYIPFAGQKELLFDPKQRVVRTAFRLLQTAYKHSKGVKDGYAKRVMHDVVVDKVLFQDQYIHLKKKYSKFLVDNWAESTDPKKHVFEDIAIAAFLIELWKKIYGAENTTNKMQFRDLGCGNGVLCYILIQEGFKGLGIDARQRKSWSIYPAEVKRCLKEQVIIPSVLLRPHPTMKLHAPHLQHNGRFFPMQLVSPQLIAPATVMYSSADLLQSPQVNIAEFPPDTFIIGNHSDELTCWIPLLGYPFMVIPCCSHNLSGNRIRYAVRDVERAKKLGNSTYQGLVDRVEYLADRVGWKTEKEMLRIPSTRNAAIIGYKNDKLNEFPTDEIYSILMEEGGADGWVANTMNLMKSNPRGH", "output": "Probable adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase."}]}
+{"id": "function_valid_4141", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLSYCLLVTGPAYGTQQASSALQFAQALLAEGHKLESVFFYREGVLNANQLTSPANDEFDLVRGWQQLGDVHQVALNVCVAAALRRGIADSQQATQLNLVGANLQPGFILSGLGELAQSVLTYDRVIQF", "output": "Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE."}]}
+{"id": "function_valid_4142", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAKKSLIQREKKRHKLEQKYHLIRRSSKKKIRSKVSPLSLSEKTKMQEKLQSLPRNSAPTRLHRRCFLTGRPRANYRDFGLSGHILREMVYACLLPGATRSSW", "output": "Binds 16S rRNA, required for the assembly of 30S particles."}]}
+{"id": "function_valid_4143", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLTLKLFVYTVVIFFVSLFIFGFLSNDPGRNPGREE", "output": "One of the components of the core complex of photosystem II (PSII), required for its stability and/or assembly. PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation."}]}
+{"id": "function_valid_4144", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEKHIPVLLKESIEYLNIKENGIYVDCTLGRAGHSSEILKKLKDGKLFSIDQDETAILEGTEKLTKISNNFKILEGNFVNISAMLAMQGIFEVDGILYDLGVSSPQFDVAERGFSYRFDGPLDMRMDRANNSLTAHKIVNEYTQEELEQILWNYGDEKFARSIAKNIILSRPINTTFELVSVIKKSLPAKILKQQKHPAKKTFQALRIRVNNEMETLESSLEQSLNLLKPKGRVVVITFHSLEEKVVKNIFKKYTLDEQQFYLSNLPYEIESSKDFKLLFKKPLKPTNTEVENNNRSHSAKLWVIEKK", "output": "Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA."}]}
+{"id": "function_valid_4145", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTSKTVTRADLASVVCRKVGLSHTESAALVELVLNEICNSLVRGEAVKLSSFATFQVRKKNERVGRNPKTGVEAPILPRRVVTFKAANVLKQRILDSHRARQKIISHE", "output": "This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control."}]}
+{"id": "function_valid_4146", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MYQLQFINLVYDTTKLTHLEQTNINLFIGNWSNHQLQKSICIRHGDDTSHNQYHILFIDTAHQRIKFSSIDNEEIIYILDYDDTQHILMQTSSKQGIGTSRPIVYERLV", "output": "Specifically inhibits the cysteine protease staphopain B (SspB) by blocking the active site of the enzyme. Probably required to protect cytoplasmic proteins from being degraded by prematurely activated/folded prostaphopain B. Also involved in growth capacity, viability and bacterial morphology (By similarity)."}]}
+{"id": "function_valid_4147", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLNRVVLVGRLTKDPEYRTTPSGVSVATFTLAVNRTFTNAQGEREADFINCVVFRRQADNVNNYLSKGSLAGVDGRLQSRNYENQEGRRVFVTEVVCDSVQFLEPKNAQQNGGQRQQNEFQDYGQGFGGQQSGQNNSYNNSSNTKQSDNPFANANGPIDISDDDLPF", "output": "Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism."}]}
+{"id": "function_valid_4148", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRILISNDDGIFAEGINTLATVLSELGEVTIVAPDRNRSGASNSLTLDYPLRIREEGDRRISVDGTPTDCVHFALNEWLDYRPDIVVAGINHGANLGDDVLYSGTVAAATEGHFLGVPAIAISLVGSTHFDTAAQVVKSIVVNLLEKPLPKNKILNINVPDIPFAELKGWKVTRLGARHRAEQMVKDVDPRGKVLYWLGPPGACQDAGPGTDFHAVEQNLVSITPLQVDLTAHDALESVELWMNEVGKK", "output": "Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates."}]}
+{"id": "function_valid_4149", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MALLEFFRPKKTTTASVAKERLQIIVAERRSAGQSTPSYLPQLKLDLLEVIRKYVNINPDQVSVNLDQKDEDLSVLELNVTLPEDK", "output": "Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell."}]}
+{"id": "function_valid_4150", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAAKIRRNDEVIVLTGKDKGKKGKITKVLATGKVIVEGINLVKKHQKPVPAMGVQGGIVEQEAAIDVSNVAIFNAETGKADRVGFRFEDDKKVRFFKSNSVTIK", "output": "One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.; "}]}
+{"id": "function_valid_4151", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAQMSTSEIRGGVKVEVEAQPYTIISNEFVKPGKGQAFNRIKMKHLLTGRVIERTFKSGEKLNLADVAEEEMRMLYKESDGVIFMDEKSFEQIKISLESIGETVQWLLDDHVYEVIFYNGNAVNVEPPTFMEMVITDTSPGVRGDTASGRVLKPAILESGAKVQVPIFVEQGEKIKVDTRTGEYVSRVSS", "output": "Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)."}]}
+{"id": "function_valid_4152", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MINQANKTAKLRVKRAVRVRKHLRGTGLKPRLCVVKSNSHIQAQLIDDETGTTLGGTATFAKEYRNTEFCKKNKASARKLGEQIAEIAKSKNIKEVVFDRGPFKYHGILAELANAARAGGLQF", "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."}]}
+{"id": "function_valid_4153", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIIGIGSDLIDITRIAKVIERHGERFLDRVFTEAERAKAERRAKKSELVAATYAKRFAAKEACSKALGTGIRQGVWWRDMGVVNLPGGRPTMVLTGGAKTRLDALTPPGMTARIDLSITDEWPLAQAFVVISAIPAAAEQAVHTSS", "output": "Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein."}]}
+{"id": "function_valid_4154", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MASTDTYNPTRDDFAAMLDESFAGGNLQESSVIKGKVVAIEKDMAVIDVGLKTEGRVPLREFAGPGRDNEIKVGDTVEVFLDRIENALGEAVLSRDKARREESWGKLEKAFQNNEKVFGVIFNQVKGGFTVDLDGAVAFLPRSQVDIRPIRDVAPLMNNSQPFQILKMDRRRGNIVVSRRTVLEETRAEQRQELVQNLEEGQVIDGVVKNITDYGAFVDLGGIDGLLHVTDIAWRRVNHPTEVLTIGQTVKVKIIKINHETHRISLGMKQLLDDPWQGIEAKYPLNARFTGRVTNITDYGAFVELEPGIEGLIHVSEMSWTKKNMHPGKIVSTSQEVEVQVLEVDSVKRRISLGLKQTMRNPWEVFVEKHPVGSTVEGEVKNKTEFGLFLGLDGDVDGMVHLSDLDWKLPGEQVIDNFKKGDMVKAVVLDVDVEKERISLGVKQLEGDPFAEPGDVKKGAVVTCEVLDVKESGIDVQIVGTDFNTFIKRSELARDRNDQRSDRFAVGEKVDARVIQFDKKARKVQVSIKALEVAEEKEAIAQYGSSDSGATLGDILGTALKQRDK", "output": "Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)."}]}
+{"id": "function_valid_4155", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSVCTEIDYKLYTELRKIAGNSLFLFNEDGDFVEVVSNSSFKFLLPVGLFSSMDIPLKKPIECNTDNDIEHSKNVVMPNLYPFQERVASEVLSSIKKKVELKRPMYVTLHLACGFGKTITTCYLLSVHKKKAVICLPNKMLINQWKRAIESININHLVSVDGVGNLLKELVKKPADILIIVSRHLSNKEFCKKIHVDYDVFVLDESHMYNLMNNSTVTRFLTYYPPKICYFLTATPRRVNRIYCNDVINVSNSSDLKKYIKIVEFFFETYSSDTIRQMVKKLNTNYNKYHMYTEKILAEDVPRNKLILDTIIYDFEKMIVNRLIIVTKLRKHMMFFYTNLIEKFGSDIVYLGDAKNKNISDIVKKIKSINRFIFISTTNYSGTGLDVPTLDSLVICSAVMNSMQIEQILGRICRYSISKTRTVIVFPNTSIKEIKHMIGFFTQKIITLAIEKLGFKKIDKKGNKQEFALCKAFNLQTR", "output": "DNA helicase which seems to act as a postreplicative transcription termination factor. Involved in ATP-dependent release of nascent RNA. Forms a stable complex with single-stranded DNA, and to a lesser extent RNA (By similarity)."}]}
+{"id": "function_valid_4156", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTSSHNNLLQNFQEYLSVEKGLSDNSIYSYGYDLNKFKNFLEKEHIDFLKVQADDIMRFLNEEKDRKISSKTIAREVVAIRQFYKFLKDEKKLDTNPTEKIETPEVMRSIPDYLTQDEIEELFASIKEDNLYELRDKCIFELLYSSGLRISEACNLRLNDMDLEGMTLTVEGKGGRQRLVPFGEKSLDILNRYLKQSRPFILKSRNCEYLFVSKKGSYINRKSVWRLLNHYIKRTSILKKVTPHTLRHSFATHLLENHADLKSVQELLGHIDIATTQIYTHMANKTLREVHKKFHPRG", "output": "Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids."}]}
+{"id": "function_valid_4157", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSNSISVSFNDEPPGSIDPVRVENFISEVLKDLNLKNWDISLLFCDDAFIQNLNKQYRDIDSPTDVLSFEQGDEYFDEAGETRFMAGDIVISLDSLSFNAEEFNVDINEELKRLIVHGILHLNGMDHSDNSPEQEMLKFQEELLMQYKNMEIYRV", "output": "Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA."}]}
+{"id": "function_valid_4158", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSQRGNRKTQVGVVVSDKMDKTVVVRVSHLVKHPVYNKYIKRSVKYKAHDTDNSCKTGDRVLIVETRPLSKDKRWKVRQIIDRVE", "output": "One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA."}]}
+{"id": "function_valid_4159", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEKNGTVHTGTVRQSLGLSLAALGVVYGDIGTSPLYAMRECFHGTHPHPATPDNVLGVLSLIVWALILIVSLKYLVFVLRADNRGEGGILALTALLNPWGDENRPPRKVLVFLGLFGAALLYGDGTLTPAISVLSAIEGLKIATPLFHPYIVPITVVILILLFLIQHRGTARVGALFGPVMVLWFTVLALLGIRGIMMAPEVLGALNPLHAVLFFVRDGWSGFQVLGAVFLVVTGGEALYADMGHFGRLPIRLAWFCCVLPALLLNYFGQGALLLSDPSEATEPFYHLAPPWALYPLVLLATLATIIASQAVISGVFSLTRQAIQLRLSPRMRIVQTSSEEIGQIYIPAVNWALMLATITLVAGFGSSSGLAAAYGVAVATTMVITALLVRFVMLERWHWHPLAVAGLTVVFLTVDLAFFGANILKVGAGGWIPLAAGLAVFTVMITWRRGRELVTTHLLAQATPLPSFLEELAAKPPQRVPGTAVFMSGRLFPAPPTLIHHLEHNKVLHEQVVILTVLTEDIPRVSASERIELKRLGQGFYRLIVRYGFMQSPNVPVILRECEPLGLVTDPETTTFYLGRETLIPTEKVSGMPHWREKLFAFMSRNSLQATAFYNLPPDRVVELGQQVEI", "output": "Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter."}]}
+{"id": "function_valid_4160", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MELTNLIEKCTKHSKDFATEVEKLWNDELSSESGLSRKTRNVIRNILRDITKSLTTDKKSKCFCILERSTINGEQIKDVYKTIFNNGVDVESRINTTGKYVLFTVMTYAAAELRLIKSDEIFALLSRFFNMICDIHRKYGCGNMFVGIPAALIVLLEIDHINKLFSVFSTRYDAKAYLYTEYFLFLNINHYLLSGSDLFINVAYGAVSFSSPISVPDYIMEALTFKACDHIMKSGDLIYIYAFTKKVKDLFNTKSDSIYQYVRLHEMSYDGVSEDTDDDDEVFAILNLSIDSSVDRYRNRVLLLTPEVASLRKEYSEAEPDYKYLMDEEVSAYDKHLPKPITNTGIEEPHATGGDKEDQPIKVVYPPNNDKDDAIKPHNPLEDPNYVPTITRTDIGIADYQLVINKLIEWLDKCEEECGNGGEFKTELEEAKRKLTELNAELSDKLSKIMSLERDSVNKTERIDRLTKEIKELRDIQNGTDDGSDSSEIDKKIIRELRESLDREREMRSKLEKELDTIRDGKVDGSCQRELELRRMWLKQRDDDLRAEIDKRRNVEWELSRLRRDIKECDKYKEDLDKAKATISNYVSRISTLESEIAKYQQDRDTLSVVRRELEEERRRVKDLESRLDECTRNQEDTQEVDALRSRIRELENKLTDCIESGGGNLTEISRLQSRISDLERQLNECRGNVTEISRLESRISDLERQLNDCRRNNETNAETERDATS", "output": "Structural protein that forms a matrix surrounding the mature virion (MV) through interaction with protein A26. Presence of protein A25 in the virion structurally prevents direct virus-cell fusion mechanism (By similarity)."}]}
+{"id": "function_valid_4161", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MHCPFCSENDTKVIDSRLVADGHQVRRRRQCLACNERFTTFETAELLMPKVIKSNGNREPFNEDKMVGGIQRALEKRPVSADAIELAISMIKSKLRATGEREVPSKMIGNLVMEQLKHLDKVAYIRFASVYRSFEDIREFGEEIARLED", "output": "Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes."}]}
+{"id": "function_valid_4162", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTNANMQGKIRIYDLARDLGRDNRDVMAVCQRLGIAHKTHSSTISEQEADSIREAFQRGLPPGGRKKAKIQQQGAAAANKQQILEVRRPPVGYQPPVRTEVSQILVSTVTPAVPTEAQPLPIPTLPELPVPEQVAEQAAAPSVQEAVEPIAVSPVTSPLPIDAADVEADNYTADEDSMPISIAQTVVEAPAAPTSEAAPPEPEPTPLPAPAAEAPQPVRPPAPPAPAKPTPAPAPAPRPTAEQPSEPRRPQPPAQPPSRPEKRGGPLIAPNRGGLQPTRPVPAQPAPQTPTRSGSGIAKKGAITKAGSGSGGGRPGGPMRRRDEREAAVVDEQPKILLLSGNISVQDLAQRMHVPTTEIIKTLFMKSVMVNINQTLDQATAELVARELGYEVQAETAVAQATKTEMLDVGDIESLEVRPPVVTIMGHVDHGKTSLLDAIRSARVAEGEAGGITQHIGAYQIEVPTEAGPRKLVFLDTPGHEAFTAMRARGAKVTDITVLVVAADDGVKPQTIEAISHAKAAGVPILVAINKVDKPDANPERVKQELTEYDLVPEEWGGKTVMVPVSAKQKLNLDLLLENLLLVADYELELMANPNRQAKGTIIEANLDKARGPVATALVQNGTLHVGDIIVVGSIFGKVRALYDDRGNRVDAAPPSMPVEVLGLTDVPQAGDEFEVYSDEREARRIADERTSKARENRLQQQMASRRVSLGAFSAQAQEGELKELALIIRADVQGSVEAIRASLEKLPQDKVQLRVLQAAAGEVSETDIDLAAASNAVILSFSTTLASGARQAAEQAGVDVREYDVIYKLLEDIQLAMEGLLDPELVEEALGGAEVRQVFPVGKGQVAGCYVKEGKLLRNAQMRVRRGKEVVFEGHVDSLKRFKEDAKEVATGFECGVGSDKFASWQPGDLIECFRMVTQKRTLN", "output": "One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex."}]}
+{"id": "function_valid_4163", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLSSGQSESLNQPMRMVICCLLLSTGLLAAVPSPAEQNALPATERQVEEVVTRLTGIMTTTQQAQSDAARPDVRMTTCSVQLEGDKSKAIYLYQEQTMSNNLGAPYRQRLLRIAASADGRAVESAGFKFVEAKPLAGLCAKPAAERLIAPMALDGDPTCTVRLVQAGDKYMGTTPEGGCQSNVRGAARITNEITLYKEGMDTRDRGFDAQGNQVWGAKEEPYRFRRLTP", "output": "Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins."}]}
+{"id": "function_valid_4164", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRHYEIVFIVHPDQSEQVPAMIERYKGMVLAAEGKIHRLEDWGRRQLAYPIQKLHKAHYVLMNVECQAETLAEIEHAFKFNDAVLRHLTIKMDRAISDASPMMKDEKAKNLLDAQPAAEVEASA", "output": "Binds together with S18 to 16S ribosomal RNA."}]}
+{"id": "function_valid_4165", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MITVALAKGALLNDSVARFQSAGLDFSAVLDPGNRQLMVPSHCGRARALLVRNGDVPVYVAYGQAQLGVVGYDVLREHQMPVAQLVDLGFGGCRMAVAVKASSGYQHAADLPPHCRVASKFTHCAREFFDALDLPVELVHLTGSVELGPLTGIAEAIVDLVATGRTLRDNGLVAIEELFQSSARLIGHPLALRLDRGDLQLIVEAMRIQESLPKNPA", "output": "Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity."}]}
+{"id": "function_valid_4166", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNIIFWGTPIFCVPILEKLLKSNHNVLAVITQPDRRRGRGNKVLPSPIKQKALEENLPIYTPVNITKEKDIQAKIKQYNADIFVVVAFGQILPKSVLKLPKYGCWNIHASLLPRWRGAAPIQWSILSGDSETGVGLMAMEEGLDTGAVLLEKKLKLKLLENAEQLSQRLKDLSCNLIIEGIEILEKVREQSQSLSKLNLTKQEDINRTYSYARLLMKEDYLINWNDSGYNIHKQILGLYPNCYTYINSKRLKVLESIPINNKYDEFLDFRYKDIILKSQSIINNNGLIIDIIENIGIIVQTKDVPLLITKVKLEGKKESSQNALIQQLTLTNSQNKLGE", "output": "Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus."}]}
+{"id": "function_valid_4167", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAKKIVGFIKLQVPAGKANPSPPIGPALGQRGLNIMEFCKAFNAKTQGMEPGLPIPVVITAFADKSFTFIMKTPPATVLIKKASGVQKGSAKPHTDKVGTLTRAQAEEIAKTKQPDLTAADLDAAVRTIAGSARSMGITVEGV", "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors."}]}
+{"id": "function_valid_4168", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDKQEAKHINMPSPSACEHKSVEAYLFIDPLCKDCWEIEPFIIKLWLEYGKYFSIRHIVTGKVDGTNASSHKWNKPANIRFVWEKTTSLQGFSCDGKVHMQEASSTPYLVSMAIKAAELQGRKAGSKFLRKLQEYIFLENVSNPDCELLLACAKDSNIDVEEFKKDLHSASAKKAFQCDLKFTNEMHITEIPSLVFFHANSDEEGIKIAGNYSYDVYVQLLKELVKCEIEPEPLPPLEVLLEATQFISSKEVAFIYDCPQQEIERELKKLQLKRKVQMIEVKCERYWKWIAKEKDLV", "output": "Adapter protein required for efficient degradation of Spx by ClpXP under non-stress conditions. Interaction with Spx stabilizes Spx and exposes the C-terminus of Spx for recognition and proteolysis by ClpXP."}]}
+{"id": "function_valid_4169", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MINKTLLQKRFNGAAVSYDRYANVQKKMAHSLLSILKERYSETASIRILELGCGTGYVTEQLSKLFPKSHITAVDFAESMIAIAQTRQNVKNVTFHCEDIERLRLEESYDVIISNATFQWLNNLQQVLRNLFQHLSIDGILLFSTFGHETFQELHASFQRAKEERNIKNETSIGQRFYSKDQLLHICKIETGDVHVSETCYIESFTEVKEFLHSIRKVGATNSNEGSYCQSPSLFRAMLRIYERDFTGNEGIMATYHALFIHITKEGKR", "output": "Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway."}]}
+{"id": "function_valid_4170", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MFEAVEELIGEHADLEKKLADPSVHADQANARKLNKRYAELTPIVATYRSWKQTGDDIETAKEFVADDPDFAAEVKDLEKQREELTEKLRLLLVPRDPSDDKDVILEIKAGAGGDESALFAGDLLRMYLRYAERVGWKTEIIDSTESELGGYKDVQVAVKTKGGQGATEPGQGVWARMKYEGGVHRVQRVPSTESQGRIHTSAAGVLVTPEAEEVDVEIHANDLRIDVYRSSGPGGQSVNTTDSAVRITHLPTGVVASCQNEKSQLQNKEQAMRILRSRLLAAAQEEAEREAADARRSQVRTVDRSEKIRTYNFPENRISDHRVGFKAYNLDQVLDGDLDAMIQACVDADSAAKLAAA", "output": "Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA."}]}
+{"id": "function_valid_4171", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEALVYTFLLVATLGIIFFAIFFREPPKVPNRGK", "output": "Seems to play a role in the dimerization of PSII."}]}
+{"id": "function_valid_4172", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKYQQLENLECGWKWKYLIKKWKDGEAITRHIDTSEADAAIAELRRIEHEPTLVLAWIEKHMSEELENKLKQAIRAKRKRHFNAEQVHTKKKSIDLDYRVWEKLSNRANELGCTLSDAIEYLLSEASRSEKASQKVTSIKEDLSKLLSS", "output": "Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain."}]}
+{"id": "function_valid_4173", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTVYAIIGGTGLTQLEGLNIRQSLPMNTPYGAPSGEIQIGDYAGREVMFLARHGHPHRLPPHQVNYRANIWALKQAGAEAILAVNAVGGIHPAMGTGHFCVPHDLVDYTSGRQHTFFADDLEEVTHIDFSYPYSEALRVRLVAALAAEGCAFSDRGVYACTQGPRLETVAEIIRLERDGCDIVGMTGMPEAALARELELEYACLALVVNPAAGKSTAVITMAEIEQALRDGMGKVKATLARVLSAS", "output": "Catalyzes the reversible phosphorylation of S-methyl-5'-thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1-phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine."}]}
+{"id": "function_valid_4174", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSGGSRIQLLSPRLANQIAAGEVVERPASVAKELLENSLDSGARRIDIEVEQGGVKLLKVRDDGSGISADDLPLALARHATSKIRELEDLEGVLSLGFRGEALASISSVARLTLTSRTASASEAWQVETEGRDMTPRVQPAAHPVGTSVEVRDLFFNTPARRKFLKAEKTEFDHLQEVIRRLALARFDVGFHLRHNGKSILSLHEAHDEIARARRVGAICGPGFMEQALPIDVERNGLRLWGWVGLPTFSRSQADLQYFFVNGRAVRDKLVAHAVRQAYRDVLFNGRHPTFVLFLELEPNGVDVNVHPTKHEVRFREGRSVHDFLYGTLHRALADVRPEDQLAAPAAVPELVRPTGQQAGEFGPQGEMRLASPVLEQPRAPQQSFSNGGSGAGYQYQYTPRPSQPLPAAEAQAVYREFYKPLETGAAPATALPESQGDIPPLGYALAQLKGIYILAENAVGLVLVDMHAAHERIMYERLKVAMASEGLSGQPLLVPETLALSQREADCAEEHAQWFQRLGFELQRLGPETLAIRQIPALLKQAEANRLVQDVLADLMEYGTSDRIQAHLNELLGTMACHGAVRANRRLAIPEMNALLRDMENTERSGQCNHGRPTWTQMGLDDLDKLFLRGR", "output": "This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex."}]}
+{"id": "function_valid_4175", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQVKNPILGLCQKAKFALSAAKVEQCPDDQGYEVAFAGRSNAGKSSALNTLTHASLARTSKTPGRTQLLNFFSLDDERRLVDLPGYGYAKVPIPLKQHWQKHLEAYLGSRECLRGVILMMDVRHPMTDFDKMMLDWAKASSMPMHILLTKADKLTHGAGKNTLLKVQSEIRKGWGDGVTIQLFSAPKRLGVEDAYRVLADWMELEDKPVV", "output": "Necessary for normal cell division and for the maintenance of normal septation."}]}
+{"id": "function_valid_4176", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MISKPDKNKTRQRRHARVRGKISGTAERPRLNVYRSNKNIYAQVIDDVEGVTLASASTLDSEVKGNNKTEKAASVGEVVAKRAAEKKIVDVVFDRGGYLYHGRVQALAEAARENGLKF", "output": "This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance."}]}
+{"id": "function_valid_4177", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNLYPWLQHSYKQIIYPHYINKGHHSIILESHKNIGITCLAKHISLWLLCQKKNKSIYHCKTCHSCQLMNSKNHPDWHYFGSNTCLSKNSSKTIGVNEVRNFTNTIFNSAQQGQNKIVYIPNIKKLTEFAINSLLKIIEEPPQNTYFLLINYLPHKIITTLRSRCIIHNLYGPTKENRIEWLKEQNINTNQKIHMSMLYSNEISFISKCKHSLFFLYQERLNFFETLLTSFQEKNFLKMLNVLNNKKCLDQIFIWICGIILDSIKWKHDINTIIINTDQTKIIQILASNFSILSLDNSYKSWIYCYNNIKNIPGINIELLFVKQLLYWEEILNIFN", "output": "DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)."}]}
+{"id": "function_valid_4178", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTANRKELAVERAAKKEAVEQLNGVFKTTSVAVVAQYSGLTVAQMQKLRQQMKQAGASVKVSKNRLAKIALEGTDVVAIGPMLKGPTVIATSNDPVAAPKVAIEFAKANEKFVIVGGSMGKTVLNVDGVKALASLPSLDELRGKIVGLIVAPATKLAQLANAPAGKLARVIQAHASKGEAA", "output": "Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors."}]}
+{"id": "function_valid_4179", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGQKINPIGLRVGVIRDWEAKWYAEKDFASLLHEDLKIRKFIDNELKEASVSHVDIERAANRINIAIHTGKPGMVIGKGGSEIEKLRNKLNTLTDKKVHINVIEIKKIDIDARLVAENIARQLENRASFRRVQKQAITRAMKNGAKGIKTQVSGRLGGADIARAEQYSEGTVPLHTLRADIDYAHAEADTTYGKLGVKVWIYRGEVLPTKNTSEGGK", "output": "Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation."}]}
+{"id": "function_valid_4180", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDKIFVDEAVTELRTIGDMLRWAVSRFNDANVYYGHGTDNAWDEAIALVFHALHLPEEIGQQVILSNLTSSEKHKIVELIIRRVRERLPVPYLTNKARFAGLEFYVDERVLVPRSPIAEMIANRFGPWLYGKPVNRILDLCTGSGCIAIACAYEFDEAEVDALDISEDALDVAQVNVETLGVMDRVFPMQSDLFSAIPEGPQYDLIVSNPPYVDEEDIGDMPDEYHHEPAIGLASGRDGLDLTKRILANAAQYLTPTGILVVEVGNSMVHLMEQFPEVPFTWVNFENGGDGVFVLTRDQLIEHQSLFAIYRDAQ", "output": "Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue."}]}
+{"id": "function_valid_4181", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTVEKSYYMTQEGKDKLEEELHYLKTDRRQEVVERIKVARDFGDLSENSEYDAAKDEQAFVEQRITQVEKMIRNAVIIENDNDNPNIVSLGKSVSFVELPDGDEETYTIVGSAEADPFEGKISNDSPMATSLLGKEIGEEVTVTTPGGDIDVRITNVE", "output": "Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides."}]}
+{"id": "function_valid_4182", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFKKLDPSPKWIVYDNNPVMHKPIEDVVFPLTKEDEHVISQMLSYVDASYEGEADKYDIRAGIGIAAIQLGCPKKIIYIHLDDKNGEHKYLMANPKIIKESTSKMYLKNGEGCLSVKKDHKGLSIRKSIVWVKGIDLFTNKEIEVKATDLLAACFQHEVDHNNNKFYYNRINESDPYYVEKNWEEI", "output": "Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions."}]}
+{"id": "function_valid_4183", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSWIILVIAGLLEVVWAVGLKYTHGFSRLTPSVITVTAMIVSLALLAWAMKSLPVGTAYAVWTGIGAVGAAITGIVLLGESANPMRLASLALIVLGIIGLKLSTH", "output": "Guanidinium ion exporter. Couples guanidinium export to the proton motive force, exchanging one guanidinium ion for two protons."}]}
+{"id": "function_valid_4184", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDMAAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLIMLVLWNAGYIIRSMQNIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPGMVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSMRDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQIALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTVSLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITFTAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSAIILQRAAR", "output": "Multidrug efflux pump that functions probably as a Na(+)/drug antiporter."}]}
+{"id": "function_valid_4185", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSKINKLEHIRNIGICAHIDAGKTTTTERILYYTGKSHKIGEVHEGGATMDWMEQEQERGITITSAATTCKWQDKVINIIDTPGHVDFTIEVERSLRVLDGAVAVFDGVAGVEPQSETVWRQADKYNVPRMCFVNKMDRMGADFYKCVDMIKDRLGAKSLILQLPIGIEENFKGIINLIKMKAVIWKDESLGAEYFEEDIPTDMQDKAAEYRARLLDMTVELDDTIMERYLSGEEITEEEIKILIRKGTIEAKFYPVLCGSAFKNKGVQPLLDAIVDFLPSPIDIGIVKGIEVSTSEEKDFPISITEPFSALAFKIMNDPFVGSLTFIRIYSGKITSGASVVNTVKNKREKIGRMLLMHANNREDIKEASAGDIVALAGLKDTSTGDTLSDIDTQVVLERMEFPEPVIELAVEPKSTADQEKMGLALSRLAAEDPSFKVSTDHETGQTVIKGMGELHLEIIIDRMRREFKVEANIGAPQVAYRETITTACEIDYTHKKQSGGAGQFARVKIIFEPLKDVIDLKDEDKNKTFVFESKIVGGAVPKEYIPGVEKGLNNIRETGIVAGYPMIDFKATLVDGAFHDVDSSVLAFEIAAKGAFREGMQKGNPKLLEPIMKVEVITPDEYMGDIIGDLNSRRGQIQSMDPRGNAQVVTAYVPLAEMFGYVNTLRSLSQGRAQFSMIFSHYDQVPSQVADIIKAKK", "output": "Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome."}]}
+{"id": "function_valid_4186", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGRYLGPSCRLCRREGIKLYLKGEKCYTDKCPLAKRGYAPGQHGQEKKKLTQYGMQLREKQKLKRYYGILERQFVRYYERAERMRGITGENLLQLLERRLDNVVYRLGFAVSRAQARQLVSHGHIEVNGKKVDIPSYLVKPGDVISVKESSRSMELIKNNLEMGRNVPDWLELNKDAFEGRVVSLPRREHIDLPVQEHLIVELYSK", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; "}]}
+{"id": "function_valid_4187", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MGGRGMNPAKMKQMMKQMGIDVKELKDVKEVIIKTADSNIVIENANVTIMTVQGSETYQIVGDAKEVPKSLEIPADDIKLVMEQTGVSEEEARNALKNSNGDLAEAIVALSSA", "output": "Contacts the emerging nascent chain on the ribosome."}]}
+{"id": "function_valid_4188", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTITEEDLIEPLRKVVEYSPPRRFLETVDMIVNVKGVDLSDPSQRIDKEVVLPHGRGKPVNVCVIAEGEMAREAEEAGATVINREKLEELAENVREAKKIARRHEFFYAQVDLMPDVGRVLGPVLGPRGKMAKPVPPNADIRALIERAHRTARVRMRDQPVIHTVIGARNMEPEQLAENAMAVLREITSELEKSWAQIDSVYVKTTMGPAERVY", "output": "Binds directly to 23S rRNA. Probably involved in E site tRNA release.; "}]}
+{"id": "function_valid_4189", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTKESLEKATFAGGCFWCMVKPFDTQPGIEKVVSGYTGGHTVNPTYKEVCSGTTGHTEAIQITFDPAVFPYEKLVEVYWQQTDPTDAAGQFVDRGDSYRPVIFYHNEEQKEIAEKSKAALDASGRFKKPIVTEIAKAETFYPAEEYHQDFYKKEKAHYEGYQVASGRAAFIDANWKG", "output": "Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine."}]}
+{"id": "function_valid_4190", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTMYAKNNTSGKDMLSLLEWNKEELTDIIKLAVAMKTNPAHYSHILSGKILGMIFDKPSTRTRVSFEAGILQLGGQAIVMSSKELQIGRGEPIKDTAHVMSEYIDAIMIRTFSHEKVEELAYHAEIPIINGLTDLHHPCQALADLMTIYEWKDQLEGIKLAYIGDGNNVCHSLLLAGAMVGIDIRLAMPKGYEVDETILAKAENLAKQSGGKIFVTEDSKLAVTDADFIYTDVWTSMGQEDENAKRLADFGEKYQVNAELVSGAKPDYHFLHCLPAHREEEVTTEIIDGIHSVIYQQAGNRLHAQKALLAAILEAK", "output": "Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline."}]}
+{"id": "function_valid_4191", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MFIGIVSLFPEMFRAITDYGVTGRAVKKGLLNIQSWSPRDFAHDRHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSELATNQKLILVCGRYEGVDERVIQAEIDEEWSIGDYVLSGGELPAMTLIDSVARFIPGVLGHEASAIEDSFADGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWLRRPELLENLALTEEQARLLAEFKTEHAQQQHKHDGMA", "output": "Specifically methylates guanosine-37 in various tRNAs."}]}
+{"id": "function_valid_4192", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MARIIALDGAQGEGGGQILRSALSLSMITGQPFEMSGIRAGRAKPGLLRQHLTAVRAATEICGAQVNGDELGSQQLRFTPGPIRGGEYRFAIGSAGSCMLVLQTVLPALWFADGSSRVEVHGGTHNQAAPSADFICRVWEPLLARMGISQRTTLIKHGFYPAGGGAAATVVEPAASLRGLTLISRGETLRTTAEALLAAVPYHVGEREVATLEAHFPQAEKNVVALEGGCGPGNALSLMIQSEQLTELFAAFGVKGTSAEAVANQVAHEARRYLASPAAVGEHLADQLILPLALAGEGAFTVARASAHLLTNIAVVERFLPVRFSCEATESGYLVRVSD", "output": "Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing."}]}
+{"id": "function_valid_4193", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGEFSTLLQQGNGWFFIPSAILLGILHGLEPGHSKTMMAAFIIAIKGTVKQAVMLGLAATLSHTAIVWLIALGGMYLSRAFTAQSVEPWLQLISAIIILSTACWMFWRTWRGEQQWLAGNHHHDHDHDHDHDHDHDHDHDHDHDHDHDHHGHIHPEGATSKAYQDAHERAHAADIQRRFDGQTVTNGQILLFGLTGGLIPCPAAITVLLICIQLKAFTLGATMVLSFSLGLALTLVTVGVGAAISVQQAAKRWSGFSTLARRAPYFSSILIGLVGVYMGIHGYTGIMQ", "output": "Efflux system for nickel and cobalt."}]}
+{"id": "function_valid_4194", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFKKLFRQDGNILNSELAEDLPIPRHVAIIMDGNGRWAKKRFLPRIAGHKEGMDVVKRVTRYANAIGIDVLTLYAFSTENWKRPTDEVDFLMKLPVEFFDSFVPELIEENVRVNVMGYRENLPEHTMRAVEKAIADTAHCTGLTLNFALNYGGRSEIITAAKEAMKELVSEGKTSEDLTEELLNDHLMSHGLGDPDLLIRTSGELRLSNFMLWQLAYSEFYFTETHWPDFSKEDFLQAIIEYQNRSRRFGGL", "output": "Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids."}]}
+{"id": "function_valid_4195", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGRKEDNIEKALRIVEHTELVRNIGIVAHIDHGKTTLSDNLIAGAGMMSEELAGKQLVLDYDEQEQARGITINAAVASMVHAFQGKEYLINLIDTPGHVDFGGDVTRAMRAVDGVIVVVDSVEGVMPQTETVIRQALREYVKPVLFINKIDRLINELRLNSDEMQKRFTKIISDVNKLISKYAPKEFTKEWQVSVQDGKVAFGSAYNNWAISVPSMAETKITFKDIVEYVKNGKQKELAQKNQLHKIILNMVIRHLPDPKTAQSYRIKQIWKGDLETEVGKSMVSCDFKGPVAMMVTKIIIDPHAGEIAIGRLFSGTVKKGTDLYISGDGKGKVQTLAMMVGPDRIPVEEVTAGNIAAIVGLKGAIAGSTVSSIENMEPFEPMIHYSEPVVTLAIEAKHTADLPRLIDVLRDISKADPSIQVDINQETGEHLISGMGELHLDVTLYRIKNDYKIEVETSEPIVVYRETVEKKGGPFEGKSPNKHNRFYFEVEPLKPEVIQAIEDGDIPQGSKFKDKKTIIETLVSKGIDREEARGLVCVEGTNIMFDVTRGIQYLDETMELLIEAFTEVMNRGPLANEKVFGVKARLVDAKLHEDSIHRGPAQVIPAGRNSIYGAMCEAKRILLEPVQKVFINVPQEEMGSAINEVQQRRGVIEDMTQEGEEVSLVARIPVSGMFGFASAIRSATGGKVLWSFENAGYQKVPPELQDSVVRSIRERKGLRPEPYDADYYASM", "output": "Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome."}]}
+{"id": "function_valid_4196", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEAQIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIETKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAMLALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK", "output": "The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication forks via replication fork reversal (RFR). RuvA specifically binds to HJ cruciform DNA, conferring on it an open structure. The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex. HJ branch migration allows RuvC to scan DNA until it finds its consensus sequence, where it cleaves and resolves the cruciform DNA."}]}
+{"id": "function_valid_4197", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLKEFQEFISKGNVMDLAVGVIIGAAFGKIVDSLVNDIIMPVIGAIFGGLDFNNYFVGLSSAVNATSLADAKKQGAVFAYGSFITVALNFVILAFIIFLMVKAVNNLRRRLEREKPATPAAPPPADVALLTEIRDLLARR", "output": "Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell."}]}
+{"id": "function_valid_4198", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MMPFSREERQFVYTWLSNMLGHELSASQLAQYQQGLFDDFFAFLTEQGFQAQVEGIQQQLQQLKTVELAHLELAADYTQLFLLDGSSSALPYASVYLPEAQLTCHFTFLEALLVRFQLQLNRDKPEPSDHLCVYLELLRQLAEVDDMKTYRQLIQDALLPWLLPFNDKVQRVKTRTTFYQQVVVLLILLLQADCQN", "output": "Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor."}]}
+{"id": "function_valid_4199", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MVVVGLDVGYGDTKVIGVDGKRIIFPSRWAVTETESWGIGGKIPVLSTDGGQTKFIYGKYASGNNIRVPQGDGRLASKEAFPLIAAALWESGIHNDGSPVDLVIGSGTPLGTFDLEVKAAKEALENKVLTVTGPEGEVRQFNITRLIMRPQGVGAALYLLNQGIIEQQPGYGVVIDVGSRTTDVLTINLMDMEPVVELSFSLQIGVGDAISALSRKIAKETGFVVPFDLAQEALSHPVMFRQKQVGGPEVSGPILEDLANRIIENIRLNLRGEVDRVTSLIPVGGGSNLIGDRFEEIAPGTLVKIKPEDLQFANALGYRDAAERSM", "output": "Polymerizes into bundles of filaments, forming a helix with a filament width of 5.5 nm and an axial repeating unit of 5.5 nm. Polymerization of Ta0583 requires NTP and is optimal with ATP, but GTP, UTP, CTP, and even the deoxy form of NTP can also support the polymerization reaction. Nucleoside diphosphate or AMP-PNP does not support polymerization."}]}
+{"id": "function_valid_4200", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGTETATLGGGCFWCTEAAMEELAGVTDVTSGYAGGDTADPSYRDVCSGTTGHAEVVQVEYDTAELAYEDVLEVFFTVHDPTTVDREGPDVGSQYRSIVLPHDDQQHERATAFVDELAAADAFDGSIVTEIEPLETFYPAAEKHQNYFEKNPDAAYCTVNVAPKVSKVREQFGARTE", "output": "Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine."}]}
+{"id": "function_valid_4201", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPIVARSSRVPWVIKYRPKRVEDVVNQDQAKKILVPWFKAWLEGRKPDKRAALLYGPPGVGKTSLVEAIASEFNLEMIELNASDYRRRSDIERIVGAASRKRSMFKRGVVILLDEVDGINPREDAGGIEALLSVIKTTENPIVMTANDPWKDFLRPLREVSLMVEFRPLTLTHIVAVLQRICEAERIECEREALRYIAERSEGDLRSAINDLQAVAEGYGRVTLTLAREIVRGREKSIDIWRTLNQVFYKPRQAWMARKAVSQSEKDYEELIAWINDNIPRKYGEPSDLFRAFDALARATVFLGRAKFGGNWELLSYVFDLMGPGVAYARMEGEVLKTRYSYPEKIRMMAQLRGVRETREKLAEVLAKRLLMSRRAVKTEVLPILHYIFRSSRDPTKPAMIALEYGLTEKMVELLAGQRKSEILKAMATVKKARLGEKPLEPQEAKARRRGEKASRDEGRKAGKRERKGVGLDFFLGEQ", "output": "Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA."}]}
+{"id": "function_valid_4202", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAHVTSVTLGEHLTGFVGEMIQSGRYGNISEVLRDALRLMEAREQRVQHVRDMVLAGTNVPVSHRLMDEIFSAAVKDTSV", "output": "Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the effect of toxin ParE (By similarity)."}]}
+{"id": "function_valid_4203", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSKIIGIDLGTTNSAVAVLEGGEAKIIPNPEGARTTPSVVGFKNGERQVGEVAKRAAITNPNTISSIKRYMGTNHKETIEGKDYSPQEISAIILQYLKSYAEDYLGETVDKAVITVPAYFNDAQRQATKDAGKIAGLEVERIINEPTAAALAYGMDKTETDQTILVFDLGGGTFDVSILELGDGVFEVHSTAGDNELGGDDFDKKIIDYLVAEFKKDNGVDLSQDKMALQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEVTLTRAKFDELTHDLVERTIAPTRQALKDANLSASDIDQVILVGGSTRIPAVQETIKKELGKEPHKGVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVMTPLIERNTTIPTSKSQTFSTAADNQPAVDIHVLQGERPMAKDNKTLGRFQLADIPPAPRGIPQIEVLFDIDKNGIVTVRAKDLGTGKEQNIVIKSSSGLTDEEIEKMVQDAEANAEEDKKNKENAELRNNADQLVFTVDKTLKELEGKIDEEEVKKAEAARDELQEALKGEDFDAIKEKTESLNEIVQNLSVKLYEQAAAEQQAAGGAEGQEAPQNDDVVDAEFEEVNDDDKENK", "output": "Acts as a chaperone."}]}
+{"id": "function_valid_4204", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTSWAEKYRPKNLDGILGNAKAVSELRAWAMAWEKGRPEVKCLILYGPPGVGKTSAALALASEMDWDYIELNASDQRTAEIIKSIAGPASQVSTFSGRRRLVILDEADNLHGTYDRGGAAAILRVIKNATQPVILIANEYYNIEKPLRDACRGVQFRSIRAQTIASLLREICRSEGIECEPEAVMHIAAMSGGDLRSAINDLEAAARGLKHLRLEDVATSERDVKASIFRVLDSIFKGEDSRSALEATYQLDESPEDLIHWIDENLPIVYKDRELAKGFECLSRADIFLGRVRRRQNYTLWRYAAFLMTGGVRAVSSKVRRGYTQFRPPSLWKRLGQTRKARSVRDSAARKIAAHCHVSTSYARSELLNFVGALLRSKKTGAAVAASLGLNIEEIALLTGSSPTTKKVQKLFEDAQKIIEAEQIAMIDRGLKIVDREIEKPEDKAMKYASVSKEIVQEKRQRSLFDF", "output": "Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA."}]}
+{"id": "function_valid_4205", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKEILPGLYILRRDRLATSPPSQEPLYGEKIVDGLRVWDPRRSKLAALLLRYPCLEGVVPSGKVLYLGAANGTTVSYLGDILTGGMIYAVEISPRAMRDLLLLAEQRENIIPVLGDAARPETYRRIVEPVDLLYQDVAQRNQAEIASRNASIYLKPNGLMVVMIKARSIDSTARSTEIFDEEIRRLSGVEVLRRVDLPHHRDHVAVVARKLR", "output": "Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA."}]}
+{"id": "function_valid_4206", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTRSEGDTWNLASSVGATATMVAAARAAATRRPRPVLTDEYAEPLVRAVGLDVFTKLASGELDPDDLERDVGFARMVDTFAARGRFYDDYFAAAGKAGLRQVVIVASGLDARPYRLSWPAGTTVYEIDQPEVIAFKTATLSRIGAAPTAELRTIGIDLRQDWPAALQDAGFDAAQPTAWLAEGVLIGFLPPEAEVRLLDSITPLSAEGSRFAADYGSLNDASQASTEQARRTTEGWRRRGLDMDIAALTYPGKHTDVAAHLGADGWATTTFGLADLFAAAGLPELTEAEQGPAATLSFVRAIKS", "output": "Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity."}]}
+{"id": "function_valid_4207", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTTTEKVQPRLKERYRNEIRDSLQQQFGYANVMQIPTVTKVVVNMGIGEAARDAKLINGAVNDLALITGQRPEIRRARKSIAQFKLREGMPIGARVTLRGDRMWEFLDRLTSIALPRIRDFRGLSPKQFDGVGNYTFGLAEQSVFHEIDVDKIDRVRGMDINVVTSATTDDEGRALLRALGFPFKEN", "output": "This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs."}]}
+{"id": "function_valid_4208", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRHFLTLNDLDKNEILDILSLAKDIKKEAKSRNYISYLKDQTLAMIFEKSSTRTRVSFEVGIHQLGGKGLFLSSRDIQLGRGEPVKDTARVLGRMVDMIMARVYKQSDLEELAKFSGVPVINGLSDDFHPVQLMSDLLTLSELGLNLQTMKVAYVGDGNNMTNSWLMAASKLGFELRVATPKGYEVPQWVLDIAKQNSKISCANLIITDNPKAAISGADVVTTDTWVSMGQEDEKEKRINDFAGYCVDDDMMSLAAKDAKFLHCLPAYRGYEVSEAVFEAHAGEIFSEAENRLHAQKAVMVWCDRKRYE", "output": "Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline."}]}
+{"id": "function_valid_4209", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MPRAQLQRFLSGISAEGIRTVYLDPKDAAKAKLDAMHSSPSSRYVVLEGRAAKPRGKKVGRRFKILSNKDIDGVLQEAQKGLDFVITEVQDWKIIPLENMIAKLHKIHTRLYAVARSPAEVRKMFSILDVGVDGVIFTASTVGDVREALVHLGTKSFRLQPARITEIREVGDGERVCVDTASMLERGEGMLVGSRSNFMFLVHNESVGSSFTSPRPFRVNAGAVHSYTLGTDGNTLYLSEVETGTEVLVLDSHGRARRAAVGRSKIERRPMLMIKAEADGEIGGIIAQDAETIRFVRPGGGLVSVTHLKKGDKVLVHSKPAAGRHFGMEVADEYILEK", "output": "Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3-dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis."}]}
+{"id": "function_valid_4210", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPKGKNLHVKIGDNVKIISGFDKNKTGEVTKIYRNTGKILVKGINFKFKHIKPNTESDVGEIKQFEAPIHHSNVKLI", "output": "One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit."}]}
+{"id": "function_valid_4211", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTEYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAIGMGLATTFVLTLASVCAWMVNSFILLPLGLVYLRTLAFILVIAVVVQFTELVVRKTSPALYRLLGIFLPLITTNCAVLGVALLNINQSHNFMQSAVYGFSAAAGFSLVMVLFAAIRERLAVADVPAPFRGSSIALITAGLMSLAFMGFTGLVKF", "output": "Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane."}]}
+{"id": "function_valid_4212", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSRIITAPHIGIEKLSAISLEELSCGLPERYALPPDGHPVEPHLERLYPTAQSKRSLWDFASPGYTFHGLHRAQDYRRELDTLQSLLTTSQSSELQAAAALLKCQQDDDRLLQIILNLLHKV", "output": "Required for Yop secretion."}]}
+{"id": "function_valid_4213", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MARPMGKLPSNTRKCAQCAMAEALLEIAGQTINQKDLGRSGRMTRTDNDTWDLASSVGATATMIATARALASRAENPLINDPFAEPLVRAVGIDLFTRLASGELRLEDIGDHATGGRWMIDNIAIRTKFYDDFFGDATTAGIRQVVILAAGLDTRAYRLPWPPGTVVYEIDQPAVIKFKTRALANLNAEPNAERHAVAVDLRNDWPTALKNAGFDPARPTAFSAEGLLSYLPPQGQDRLLDAITALSAPDSRLATQSPLVLDLAEEDEKKMRMKSAAEAWRERGFDLDLTELIYFDQRNDVADYLAGSGWQVTTSTGKELFAAQGLPPFEDDHITRFADRRYISAVLK", "output": "Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity."}]}
+{"id": "function_valid_4214", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTILSDVKALGQQIWLDNLSRSLVQSGELAQMLKQGVCGVTSNPAIFQKAFAGDALYADEVAALKQQDLTPKQRYETMAVADVQAACDVCLAEHESTGGKTGFVSLEVSPELSKDAQGTVEEARRLYAAIGCKNAMIKVPATDAGIDALETLVSDGISVNLTLLFSRVQTLKAYAAYARGIAKRLAAGQSVAHIHVVASFFISRVDGALDTTLPDHLKGKIAIALAKAAYQDWAQYFGSPEFAALETQGANRVQLLWASTGVKNPAYPDTLYVDSLIGAHTVNTVPDATLKAFIDHGTAKATLTEGADEAQAQLAETAALGIDVETLAARLQEDGLKQFEEAFEKLLAPLV", "output": "Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway."}]}
+{"id": "function_valid_4215", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAKAKFERTKPHVNIGTIGHVDHGKTTLTAAITKVLHDKYPELNESRAFDQIDNAPEERQRGITINISHVEYQTEKRHYAHVDAPGHADYIKNMITGAAQMDGAILVVAATDGPMPQTREHVLLARQVGVPYILVALNKADAVDDEELIELVEMEVRELLAAQDFDEDAPVVRVSALKALEGDEKWVKSVEELMDAVDESIPDPVRDTDRPFLMPVEDVFTITGRGTVVTGRVERGVVNVNEEVEIVGIRPGTTKTTVTGVEMFRKLLDQGQAGDNVGLLLRGIKREDVERGQVVVKPGTTTPHTEFDGQVYILSKDEGGRHTPFFNNYRPQFYFRTTDVTGVVTLPEGTEMVMPGDNTDISVKLIQPVAMDEGLRFAIREGGRTVGAGRVTKIHK", "output": "This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis."}]}
+{"id": "function_valid_4216", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKIMGKKARNAALVLAVVSAEQKKHALEMIALSLESQADEILCANNQDLINAAQNNMAAAMIDRLKLDELRLCAMIDSVRQIACLPDPVGQVINAWTRPNGLHISCVRTPLGVIGIIYESRPNVTIDASCLCLKSGNAAILRGGSDSFHSAYALHSALAMGLEKAGLPTDAIQMVETTDRDAVGEMLKGLDGTIDVIIPRGGQSLVKRVQSDARVPVFAHLAGLCHIYIDQSANVEMARDIVLNAKLRRTGICGAVETVLIDRQALEKFLPVLIALQEKGCEIRATEDIVSLVPTFALACEEDWSQEYLDAILSVKTVEGVEGAIEHIVRYSSGHTESIIAEDVGVVEIFFNRLDSAILLHNASTQFADGGEFGFGAEIGIATGKMHARGPIGVEQLTSFQYQIRGNGQVRP", "output": "Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate."}]}
+{"id": "function_valid_4217", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGLMIFAYIAIGAVLGAGTGYLLHRYVSAKRIGDANELAKRIVEEARKEAQAQKKEILLQGQDEIFNQKRELENEFKERERELKARDRKLEEQGERLEEKLEKATQKEHEVLAIEKELTRKERRLATLEEELEGKIAEQDHRLEEVSGLTAEEARARIMEEVEARTRHESAKMIRVIEMEARETADRKAKEILASAIQRYAGDYVGEQTVTAVTLPSEDMKGRIIGREGRNIRALEAATGVDLIIDDTPETVILSAYSPLRRQVAKMALERLIQDGRIHPARIEDIVRKCEQELEVQVREVGEQATFDAGVHGIHPDIIKLLGQLRYRTSFSQNVLQHSLEVSALCGMMAAELGMDIKKAKRAGLLHDIGKAVDHEVEGPHALIGADIAKKYGEGKDIIHAIAAHHEDQPPKTALAVLVQAADSISGARPGARKELLENYVKRLEDLENIATGFEGVSKVYAIQAGREIRVMVNSENVDDDQTYMLCKDIAAKIEKNLTYPGQIRVTVIRERRAVGYAK", "output": "Endoribonuclease that initiates mRNA decay."}]}
+{"id": "function_valid_4218", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRQHVNPLSQFFQLPLSLPSKNILFEKSHYPIHLDIGSAKGEFLIELATKYPDWNFVGLEIREPLVSLCEKKRRKLELTNLKFLFCNVNVSLDEWLSDLDFGQLKRVSIQFPDPWFKRKHFKRRVLNTNILNSIAKSMSKDGEIFIQSDILKLIEYMTNTIDENRYFTRKNVGDLRSIDKNPYDVMTDREIFSLKKNLLIYRVMYIRNSLLFTN", "output": "Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA."}]}
+{"id": "function_valid_4219", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDSSTLIKRLETAKSSFQNLELQLADPDVASDPKQLETIARERSRLEPLVNDYLKLQIIEKECLEAKGLVKESRDDKEMELLAREELQNLELSKNELIQKLTLALLPKDPRDERSVMLEIRAGAGGNEACLWAGDLARMYERYGQKLGWNVKPISSTEADMGGFREMIISVKGESVYSQLKFEAGVHRVQRVPSTESQGRVHTSTATVAVMPEADPVEVKIESTDLEISTARSGGAGGQNVNKVETAIDLFHKPSGIRVFCTQERSQMQNRERAMEILRAKLLELEIAEANAKERSARLSQVGTGDRSEKIRTYNYKDNRTTDHRLGVNFPLEQVLSGQLEDVIGACIAEEQKRQMEELSNQSED", "output": "Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA."}]}
+{"id": "function_valid_4220", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MVRLREIPRTATFAWSPGAASPLIATGTRAGAVDVDFSNQTCLELWDLALSRHETGGELQPVAKIDTDSGFNDLAWTESEDNSRGVIAGALENGSLDLWDADKLLNGSDDAVISRTSKHSGAVKALQFNPKHSNLLATGGAKGELYISDLDNIANPYRLGGTAARADDIECLDWNKKVAHILVTGSSAGFVTVWDVKTKKESLTLNNMGRKAVSAVAWDPEKPTKLVTATPLESDPLICVWDLRNSHAPERTLRGHESGVLSLSWCAQDPDLLLSSGKDNRTMCWNPQTGHAYGEFPVVTNWTFQTRWNPHNPNFFATASFDGKISIQTIQNTSTETAQAIADQNQALDGEDFFAKAQTQPQVSSFSLPKPPKWLERPCSATFGFGGRVVSVNLVEKGQRASKIKITPFEVDEAVGKSTETFETALKEGDLRSICESRAANAGSDEEKADWKVIEALISKDPRKGLVEYLGFADQADEAADSLSKLGLDKEEEVNGEVAKESRGSGAKKHRRLQSMFDANPEADSFLSDLAASKGAKTNNPFHIFNGSENEADTGITRALLLGDFEKALDVALKEDRLSDAFMIAICGGPKCIEKAQEHYFQKQTNSPNYVRLLASIVGKNLWDVVYNADLSNWKEVMAALCTFADEKDFADLCEALGDRLEEELRNNEDKGMRKDASFCFLAGSKLEKVVAIWIEELREHEQKAIETAADDSAFSIHVRALQGLIEKVTIFRQVTKFEDTERTKESDWKLSTLYDKYIEYADVVATHGRLQVAQKYLDLVPEKHPEAEIARNRIKLATRQATPQRTQPAAATVTRAALNKPLPQPNAFQPQRAYSPATPAAVPSPYAPAAAAANAYAPPTTATNPYAPSTASAPAQPVNPYAPPAGGSSYTPAGYQPPKAPAYGAQPLGGGVPPPPRASNQSPAPTVTTYTTATNLPAWNDLPEGFAKAPTPRRSTPAAATVASPFPNQSPTLTQGPPPPAGQRAPSVPPPPKGTAPPPRMTSPPAAQPASTTMPPPPANPYASLPQSPPMASTMGVPASIPRGPSPYNAPPTMPPPPNRYAPSPAAQAASPQLQTRAPVPPPPQAAASPYAPQPPAAGHYVPSTPPPHVQPPPQQAPPPQAAPGSRPSTASSQKKPAPAPPKYPPGDRSHIPADAMPVYEILSADMQRVKSRAPSSFKAQVDDAERRLNILFDHLNNEDLLKPNTIADMAELARAIQARDYETARTIHVDIMTNRLDECGNWMVGVKRLISMSRATP", "output": "Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity)."}]}
+{"id": "function_valid_4221", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MHELLLFASVPAHQHHELLQQLAGLTAMQPRHRLERRLVFKAYRKPGLTNTRVGASQDLQGVELQRLNKMLNGGMFYTQVVGPVAKADFGGNPSSSGDPDVSMSGLEEKPSSSSSSYSYEDQPWKLEFRDIPEAGTRSAVTARLMASATLPKGDITAPMNAWGYSFVTEYVVEGDVFVLNDIVIFLHRVLLYPTGAQESHGPRRQLPAYQELSPLERTGSYVLQAAITVQDGGNQEMMRTASQHLFGLREQLKSAVRLEMADRLSLDTRAK", "output": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity)."}]}
+{"id": "function_valid_4222", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAKTATPGACASDPGSGPLPENYEMALAELEALVARMEGGTLSLEDSLAAYRRGAALVAFCQQQLEKAEQQVRVLDGASLKPLSAGTAAADGEDDDL", "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."}]}
+{"id": "function_valid_4223", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAKISKRRQAFAAKVDRQKLYPIDDALALVKECASAKFDESIDVAVQLGIDAKKSDQVVRGSVVLPAGTGKSVRVAVFAQGEKAEQARAAGAEVVGMEDLAEQIKAGQMDFDIVIASPDTMRIVGTLGQILGPRGLMPNPKVGTVTPDVATAVKNAKAGQVQFRVDKAGIIHATIGRASFEPTALRTNLSALIEALQKAKPATSKGVYLRKIALSSTMGVGVRVDQGSLAAQ", "output": "Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.; "}]}
+{"id": "function_valid_4224", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKAELPEPLKKDGFGEYKLMPESIDDLWHLSHLISPGNTVYAVTLRTVDGPSDKLRSEKLEKRPVRIGVKCEKAEFVPESSRLRVFGVISYGPDMGQHHTLNIEAGYEISVVRQWRQIDLARLERAVSSSVHGVVHIAAIEDGEAELYRVRQYGPERITTLTVGSGKTAELDSRQALFAELLTFLEKVTGSIVIAGPGFVKEDFVKFAKTKAPEIAERMLIADTRRCGYGAVQEAIGNGVLTRVAEDLQLAKEVSFMDEVFLRIGQNGAVAYGKSEVRQAIDYGAAETILVADSFVKDGGIEKMIEGAERLGANVVVLSTEFEPGTRLVGLGGVAALLRYKI", "output": "May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity."}]}
+{"id": "function_valid_4225", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIKQEFLKKMQEKKYFQDHRKVLIAVSGGLDSMTLLQLLIVSQKELAIELAIAHVNHKQRPESDQEEKALVKIAEQLGVKIFTSSFSGNFSENAARQFRYDFFGKVMQEGHYTALVTAHHADDQAETVFMRLLRGARLRHLSGMKAVQPFACGELIRPLLTFHKSDFPDIQHFEDSSNFQNDYLRNRIRNLYLPDLEKENPQFKDSLRYLGKEIEDWQTALSHLTRDLDIENVQVFHQQIPQVQRFLLQNYLENFSGLNLSKQQFEEVLNILQTKANYQHTLKKDYELVKDYQRFEIRKISRKPDLKMDSILLEFENLIEFGYYRFSFGIPLSGENIQKIFVSRETSLTLRFRKEGDSILLNGHHKKLRRLFIDKKVSFEERNSSVVVEQNHQILAILNIAISDLSKALKSDIMSTVLYIQKIDG", "output": "Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine."}]}
+{"id": "function_valid_4226", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRVRNRKGATELLEAHPQYVILNPADAKGRWQEIFGNDHPIHVEVGSGKGAFVSGMAKANPEINYIGIDIQKSVLSYALDKVLATDVPNIKLLWVDGSDLTDYFEEGEIDRLYLNFSDPWPKKRHEKRRLTYQSFLATYQQILPENGEIHFKTDNRGLFEYSLVSFSQYGMKLKGVWLDLHASDFEDNVLTEYEQKFANKGQVIYRVEAAFE", "output": "Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA."}]}
+{"id": "function_valid_4227", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MARFQEFYKEKVVPGLIEKFGYKSVMEVPRITKITLNMGLGEAVADKKIIENAVGDLTKIAGQKPVVTKARKAIAGFKIRQGYPIGAMVTLRGRAMYEFLDRFVTVALPRVRDFRGVSGRAFDGRGNYNIGVKEQIIFPEIDYDKIDALRGLNISITTTAKTDDEAKALLASFKFPFRN", "output": "This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs."}]}
+{"id": "function_valid_4228", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MFWFKNVMIYRLTSPLSLESHSLEDQLQQTKFTPCSQSDMSKFGWSSPLSGSELLHFSQSKQFLLVSHKEDKLLPANVIKKETEERIAVLEEKEARKLKKTEKQAIKDDVVAMLLPRAFSKHQFTAIWLDLDAQLVYVDAGSSKRAEDTLALLRKTLGSLPVVPISFALLPSEVMTNWIAKGHTPNWLNLLEEAELKSFDTDSVVRCKRQDLESEEIAQHLQASKFVTKLAIDWENHFSCVLNEDATLSRVKFADEVREKNDDILKEDIAQRFDADLLLMTEELKLFTQKMIEEFGGIKERI", "output": "May be involved in recombination."}]}
+{"id": "function_valid_4229", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSSGVQGGPAAHANAYQTHPLRDAASALGTLSPQAYVDVVSAAQRNFLERMSQLASEQCDAQPAAHDARLDDRPALRAPQERDAPPLGASDTGSRASGAAKLTELLGVLMSVISASSLDELKQRSDIWNQMSKAAQDNLSRLSDAFQRATDEAKAAADAAEQAAAAAKQAGADAKAADAAVDAAQKRYDDAVKQGLPDDQLQSLKAALEQARQQAGDAHGRADALQADATKKLDAASALATQARACEQQVDDAVNQATQQYGASASLRTPQSPRLSGAAELTAVLGKLQELISSGNVKELESKQKLFTEMQAKREAELQKKSDEYQAQVKKAEEMQKTMGCIGKIVGWVITAVSFAAAAFTGGASLALAAVGLALAVGDEISRATTGVSFMDKLMQPVMDAILKPLMEMISSLITKALVACGVDQQKAELAGAILGAVVTGVALVAAAFVGASAVKAVASKVIDAMAGQLTKLMDSAIGKMLVQLIEKFSEKSGLQALGSRTATAMTRMRRAIGVEAKEDGMLLANRFEKAGTVMNVGNQVSQAAGGIVVGVERAKAMGLLADVKEAMYDIKLLGDLLKQAVDAFAEHNRVLAQLMQQMSDAGEMQTSTGKLILRNARAV", "output": "Plays a role in the bacterium-induced formation of multinucleated giant cell (MNGC), which is formed after host cell fusion, as well as in the intercellular spreading of bacteria and in the induction of apoptosis in macrophages. May act in concert with other effector proteins to induce fusion of host cell membranes (By similarity)."}]}
+{"id": "function_valid_4230", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MGRTLENKQQIVTEIKSLLNDSEMAVVLDYKGLTIKEMSDLRSRLQTTNGICKVTKNSLMRKAIDGDSNWNDLESLLTGTNAFVLIKEDVGGAVKAIQSFQKDTKKSETKGALFEGRLLSDSEIKEIASLPSKEVLMAKIAGALNGVATKIAISINEVPSGLARSLKQHSEKSES", "output": "Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors."}]}
+{"id": "function_valid_4231", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTKTDRVCVGAIAGAFGVKGEVRLKSFCTEPTDIASYGPLSTEKGDRSFRVTLTRPVAGGLGARLSDVTTKEEADALRGVGLYVDRARLPSLGDDEFYHADLIGLEVRDTGGALLGRVHAVHNHGAGDILEIAGAVGREGLLLPFTRAVVPTVDLAAGRIVADPPEGLD", "output": "An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes."}]}
+{"id": "function_valid_4232", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MYVRHLQVTDFRSWPHADLTFEPGPTVLVGSNGQGKTNLVEALGYVATLGSHRVATDAPLVRYGTQRAVVRAAVVNHGRELLVELEITPGKANRARINRGAAGKPRDVLGILRTVLFAPEDMAMVRGDPGERRRFLDDLLVARAPRYAGVRSDYDRVLRQRSALLKSAGAAKRGGSGGDLRTLEVWDGHLARYGAELLAGRLDLVAAIAPHVTSAYANVAATAEETAPSGRVADVRYRSSLGESLPEGYGVPRGEPADVEVLEKALLAELERVRAQELERGVSLVGPHRDDLELMLGELPAKGYASHGESWSFALALRLASYHLLAEDGAEPVLILDDVFAELDRRRRSRLAELVAGAEQVLVTAAVAEDVPEELTGVRFDVREGEVRRVE", "output": "The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP."}]}
+{"id": "function_valid_4233", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIFLTLEHILTHISFSVVSIVIIIHFLTLLVNEFVGLYDSSEKGMLTTFFCLTGLLITRWIYSGHLPISDLYESLIFLSWIFSIIHMVPYFKKHKNYLSTITAPSTFFTQGFATWGLLTDMHQSKILVPALQSQWLIMHVSMMVSGYAALLCGSLLSAALLVITFRKVIRIVGKNNNLLNDSFPVDEIQYMMEKKSILKNTFFPSSRNYYRFQLIQQLDHWGFRILSIGFLFLTIGILSGAVWANEAWGSYWNWDPKETWAFITWTIFAIYFHTRTNKNLEGLNSAIVASIGFLIIWICYFGVNLLGIGLHSYGSFTLISN", "output": "Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment."}]}
+{"id": "function_valid_4234", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKFLLLVLAALRFLTQVIPASAGGSKCVSNTPGYCRTYCHQGETALFMCNASRKCCVSYSFLPKPDLPQLIGNHWQSRRRNTQRKDKKQQTTVTS", "output": "Has antibacterial activity."}]}
+{"id": "function_valid_4235", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKNCMMADQRGRSILKHQPVVGDEALEFSRGLAPSTFGFRYAAYMDRNHFLPSGRTAVKHIADPTLAYVMTRYRQCHDFVHIITGCGRSIEEELAVKIFEWKHTGLPLGLLSLLGGAPRLAAAQWAHMRLYWEWASRNAPCSRHGEPAVPMYLNVPWEDMLAKEYDEVVAYTGITPLPQFLEKRQQH", "output": "Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides."}]}
+{"id": "function_valid_4236", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSTYTPKAGDTTRSWYVIDATDVVLGRLAVEAAKLLRGKHKPTFTPNVDGGDFVIIINADKISLSGDKLTKKFAYSHSGYPGGLRKRAIGDLLAKHPTRVVENAITGMLPHTKLGRQIQKKLKVYAGPEHPHTAQQPVPFEIKQVAQ", "output": "This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly."}]}
+{"id": "function_valid_4237", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKQPNKAPRANIAAPKGTATPKRRRKTRDELDAEARDRKRQKKHSGNRSGARTNVEGSNKKGHSQTQEKDPRVGSKVPVPLVIESQVKAKSMPKPVEKNVVKPRLTPEEELAKLENDERLDALLDRLDNDEVLNKEDQAYVDLTLDRIDALMEQLGIELGDDEDDVEREEKQEDILQLLKRGNPKDTF", "output": "A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis."}]}
+{"id": "function_valid_4238", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSGTLLAFDFGTKSIGVAIGQRITGTARPLTAIKAQDGTPDWTLIERLLKEWQPEAVIVGLPLNMDGTEQPLTARARKFANKIHGRFGAVVKLHDERLSTVEARAGLFEHGGFRALNKGSVDSASAVIILESFFEQGF", "output": "Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA."}]}
+{"id": "function_valid_4239", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVSDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN", "output": "Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters."}]}
+{"id": "function_valid_4240", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDIVFMGTPDFAANILQKLIEEPQFNIKLVVTQPDKPVGRKQILTPPPVKEFALKFNLNVVQPDRLKGNEEFFEVLKKINPEVIVVVAYGKILPKEILQIPKYGCINVHASLLPEYRGAAPIQRVLMDGKNYTGITIMKMDEGLDTGDILLQEGIEIEQNDDVITLSKKLSELGAKLLIETLKNISNIVPVKQDATKATYAPPIDKKEGQISWDMSAVQIYNRFRALKIWPGIFTIYKGKLLKIHEMEIAKLDNLENVQNGTILGINETGILVKVKDGVIKLKELQLEGGRKMSARDFVNGYKIKKGDILS", "output": "Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus."}]}
+{"id": "function_valid_4241", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTHYIQGQWHTGNGHDVTSINPANGETIWCGKTATAEQVNTAVEAARAAQFDWFMLGFDARLAIVEAYRSQLEANKAELAETIAQETGKPQWETATEVGAMIGKIALSAAAYHKRTGTEANDTPAGRAVIRHKPHGVVAVFGPYNFPGHLPNGHIVPALLAGNTVIFKPSELTPKVAELMVKLWDKAGLPAGVINLVQGEVDTGKALASHPQIDGLFFTGSSRTGHLLHQQYAGHPGKILALEMGGNNPLIIKGVQDIKAAVHDILQSAYISSGQRCTCARRLYVEQGEQGDALIALLVDAVKQIKVGPWNAQPQPFMGSMISETAAKGMVAAQANLLDLGGKVLVELTHLQAGTGLVSPGLIDVTAIDVLPDEEYFGPLLQLVRYGDFDQAIKLANQTRYGLSAGLLADSREDYDYFLARIRAGIVNWNKQITGASGAAPFGGVGASGNHRASAFYAADYCAYPVASVEADAVSLPATLSPGLSL", "output": "Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate."}]}
+{"id": "function_valid_4242", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTINALLLSSSRVGDTPYLAHAIPFIKPLTTQAQKWIFIPYAGVSMSYDTYLASVVMGLAELNLDISGIHQHPDPCQAIKDADGILIGGGNTFHLLHELYRYNLINLIREKVAQGTPYVGWSAGANVSGASIKTTNDMPIIEPPSFDALKIVPFQLNPHYSNYRTPGHNGETRAQRLLEFTKVEPLTPVIAIAEGSALWRRDNTLVLLGENPAYLFCGEQQEMLIPIGSDLSHLLK", "output": "Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids."}]}
+{"id": "function_valid_4243", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPEPIIIEPEPAVAGSLFGDRIDVAREFTAQLGQRGEELGLIGPLEPPRLWSRHVINSVLVAPLLRPGLVGDIGTGAGLPGLVLAIARPDVDFVLIEPMERRVAWLEEQVAHLALGNVSVRRARAEEVAQEFNLDQVTARAVSAFAKLIPLTVPLVKTGGELVLMKGSNAEREVEAASKAIRKYHLEDVEVITLGSGQVDEVTRVVRARVA", "output": "Specifically methylates the N7 position of guanine in position 518 of 16S rRNA."}]}
+{"id": "function_valid_4244", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSNPITITESAQSHFAKLLAQQPEGTNIRVFVVNPGTQNAECGVSYCPPEAVEATDTEYPFSGFSAYVDGLSLPFLEEAVIDFVTDKMGSQLTLKAPNAKMRKVSDDASLMERVEYALQTQVNPQLAGHGGHVRLISISDDGVALVQFGGGCNGCSMVDVTLKEGIEKELLAQFAGELTAVRDSTEHDRGEHSYY", "output": "Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins."}]}
+{"id": "function_valid_4245", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MESTSPALSVSIAVLTALLGLTGFGIYTAFGPPSRQLDDPFDDHDD", "output": "May play a role in photosystem I and II biogenesis."}]}
+{"id": "function_valid_4246", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKVSEFDYELPSELIAQEPVEPRDASRLMVLHRKTQRIEHRIFREIIEYLEPGDLLVLNVSKVIPARLYARKKTGASIEILLIERLEEGIWKCLVRPGQKVKKGTELVIDEDLSAVCLGRGEDGTRILKFQPQDDRLIFEKGRTPLPPYIKNEVPLERYQTVYAKEEGSVAAPTAGLHFTPELIEKLKKKGVQFAEVVLHVGIGTFRPVKVEEVEKHKMHEEFYQVTKETIKKLRETRERGNRIVAVGTTTVRTLETIARLPEQEEYVGKTDLFIYPPFEFKLVDALITNFHLPRSTLLMLVAAFAGKDFVMEAYREAVKRRYRFFSFGDAMLIL", "output": "Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)."}]}
+{"id": "function_valid_4247", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTIRHLSETIINQIAAGEVIERPASVIKELVENAIDAGATRIEVVTAGGGKTLLRVTDNGSGIPADELALAVSRHCTSKLTDDVHDIRALGFRGEALPSIGSVSKLTLKSRPQDADSGFEVCVTGGHLDGPRPTALNRGTIVEVRDLFYATPARLKFMKTDRAEATAITDVVKRIGIAFPHIRFSLAGTDRTPFEMPATGTGAEATLERIGQVLGREFGENALAIDAERDGVRLAGFVGIPSFNRGNALHQFAYVNGRPVRDKQIFGALRGAYSDVIARDRHPVAVLFLTLDPALVDVNVHPAKADVRFRDPGLVRGLIVGAIKQALAQSGIRPATSGAEAMLQAFRAEGFGAQQSAPRPANSYSPASWRTAPPAPRSEWSPQTAHPAHRPLDLQAAPALRENGQAVLGDVAVPAADARASVAEAPVELMQKPLGAARAQIHENYIVAQTEDSLVIVDQHAAHERLVYEALKNALHARPIAGQMLLIPEIVDLPEEDAQRLAGHAETLARFGLGVEQFGPGAIAVRETPAMLGEMNVQQLIRDLADEIAEHDTADGLKAMLHHVAATMACHGSVRSGRRLKPEEMNALLRDMEATPGSGTCNHGRPTYIELKLTDIERLFGRR", "output": "This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex."}]}
+{"id": "function_valid_4248", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIFVILEHILTHISFSIIAIVITTHLMTLLVHEIVGLCDSSEKGMIATFFCITGLLVTRWIYSGHFPLNDLYESLMFLSWSFSLILMVPYFKNHKNHFSTITAPSAICTQSFATSGLSTEIHQSEILVPALQSHWLMMHVSMMLLSYAALLCGSLLSIALLVITFRKNIDMIGFTNHLLIWPFSFGEIKYLNEKRSLLKNTSFLLFRNYHRYQLTQRLDHWSYRVIGLGFTFSTIGILSGAVWANEAWGSYWNWDPKETWAFITWTISAIYSHTRTNKSLQGMNSAIVASMGFLIIWICYFGVNLLGIGLHSYGSFT", "output": "Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment."}]}
+{"id": "function_valid_4249", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPNLQTVAQLISLFLILTSGPAIIVLIALRRGNL", "output": "A core subunit of photosystem II (PSII)."}]}
+{"id": "function_valid_4250", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSQETEKDLEQTQNEELVEEAQSDEKKDQEVDPVEAAQAEAAEYKDKYIRAHADFENAKKRLEKDKMNAVAYANESFAKDILAVLDSFENALSAIEGANKENAAEVLEKMQEGVKLTYEQLKKVLEKNSIKEIESKGTFNPEVHQAIMQVDSDEHKTDDIVQVMQKGYTIKDRVLRPAMVSTAK", "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding."}]}
+{"id": "function_valid_4251", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAMKKLLIASLLFSSATVYGAEGFVVKDIHFEGLQRVAVGAALLSMPVRPGDTVTDDDISNTIRALFATGNFEDVRVLRDGDTLLVQVKERPTIASITFSGNKSVKDDMLKQNLEASGVRVGESLDRTTIADIEKGLEDFYYSVGKYSASVKAVVTPLPRNRVDLKLVFQEGVSAKIQQINIVGNHAFSTDELISHFQLRDEVPWWNVVGDRKYQKQKLAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYITVNITEGDQYKFSGVQVTGNLAGHSAEIEALTKVEPGELYNGAKVTRMENDIKKLLGRYGYAYPRVQSQPEINDSDKTVKLHVNVDAGNRYYVRKIRFEGNDTSKDAVLRREMRQMEGAWLGSDLVDQGKDRLNRLGFFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWLGTGYAVGINGTKNDYQTYTELSVTNPYFTVDGVSLGGRVFYNDFDANDADLSDYTNKSYGTDITLGFPVNEYNTLRAGVGYVHNSLSNMQPQVAMWRYLNSMGQYPDNTNDRNSFSANDFTFNYGWTYNKLDRGFFPTEGSRVNLNGKVTIPGSDNEYYKATLDTATYVPIDNDHQWVVLGRTRFGYGDGIGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAVYFPASSRHDDDDSYDNECKSTESAPCKSDDAVGGNAMAVASLELITPTPFISDKYANSVRTSVFWDMGTVWDTHWDSSAYAGYPDYSDPSNIRMSAGIAVQWMSPLGPLVFSYAQPFKKYDGDKAEQFQFNIGKTW", "output": "Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery."}]}
+{"id": "function_valid_4252", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEISYGRALWRNFLGQSPDWYKLALIIFLIVNPLVFAVAPFVAGWLLVVEFIFTLAMALKCYPLLPGGLLAIEALLIGMTSPAHVREEIAGNLEVLLLLMFMVAGIYFMKQLLLFVFTRLLLGIRSKMLLSLAFCLAAAFLSAFLDALTVVAVVISVAVGFYGIYHRVASARPDDSDLLNDSHIEQHYREVLEQFRGFLRSLMMHAGVGTALGGVMTMVGEPQNLIIAKAAGWHFGEFFLRMAPVTLPVMVCGLLTCLLVEKYRLFGYGEPLPPTVRKVLQEFDDRSRAQRSRQERLRLIAQALIGVWLIVALAFHLAEVGLIGLSVIILATTFTGVTDEHAIGKAFTEALPFTALLTVFFSIVAVIIDQQLFTPVIEFVLQASPHAQLSLFYLFNGLLSSISDNVFVGTVYINEAKAALEHGAISLPQFEMLAVAINTGTNLPSVATPNGQAAFLFLLTSALAPLIRLSYGRMVWMALPYTIVLTLVGLLCVEFTLMPVTDWLLAHGWLVTPTLP", "output": "Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons."}]}
+{"id": "function_valid_4253", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSKEDVIEVEGVIKEALPNATFQVELENGHVVLAHLSGKLRMHFIRILPGDKVTVELSPYDLTRGRITWRKK", "output": "One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex."}]}
+{"id": "function_valid_4254", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSRRHRAEKREINPDPKFGDLVVTKFMNAIMLHGKKSVAESIVYGAFDAVQSKLKQEPVTVFHSALDNIAPHVEVRSRRVGGATYQVPVDVRPERRQALAIRWLIAAARKRNETTMVDRLCGELMDAANNRGSAVKKREDTHKMADANRAFSHYRW", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."}]}
+{"id": "function_valid_4255", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MARVTVEDAVEQIGNRFDMILVAARRARQIAVQGKDPMVEEMNDKPTVIALREIELGLVNAHTLDADERQTVREREAAEIAAVSAIAEGRSL", "output": "Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits."}]}
+{"id": "function_valid_4256", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MVIKAQSPAGFAEEYIIESIWNNRFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHDSVPQLIDNLLAVRTNIATIFVRTAIRHHPEKAQEILARAKTVDDNAEAFTALDYGIFRGLAFASGNPIYGLILNGLKGLYTRVGRYYFSNPEARKLALTFYNKLSTLCDTESYDQVLECLRTYGKESGAIWHSMQGTMPSDLAEARR", "output": "Multifunctional regulator of fatty acid metabolism."}]}
+{"id": "function_valid_4257", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKLVVGLGNPGPEYARTRHNVGFLVADRLALALRAEFTLRKFASELAEGRAGGERVWIMKPQTYMNHSGESVGSALHFWKLGLEDLVVVHDDLELEPFRVQLKVGGGHGGHNGLKSVNAHVGGPDYARVRVGVGRPPPRMDPADYVLGRFAKADEAPLEECLVRATEAARLAIELGAAKAMNQVNRRASAAG", "output": "The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis."}]}
+{"id": "function_valid_4258", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MANLAQPAAKELAGHPLVVIPARMASTRLPGKPLADICGTPMIVQVWRRAMEAGVGRVVVAAAEKEIADAVREAGGEAVLTDPDLPSGSDRVWQAVCEVDPEGHHTVILNVQGDLPTLDPALIRTAYEALVRPGADISTLAATITVEEERTNPNVVKAVASFGEGRLARALYFTRATAPWGEGPLYHHIGLYGYRREALARFVALPPSPLEVREKLEQLRALEAGMAIEVALVDTVPLGVDTPADLEKARAALARRSV", "output": "Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria."}]}
+{"id": "function_valid_4259", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MLSVNELALEIFDNLADLAEEFNAVYHELDNGARIVDCGVSTRGGYAAGRAFTEICMGGLGEVNFRMGQIKEFPQPFIDVNTDFPSIACLGAQKAGWTVKVGNYFAMGSGPARALSLKPKHTYEVIDYEDDYDCAVICLESDHLPNAEVMNKIAEECHVDVANTCAVVAPTSSIVGSIQVSGRCVETAIYKLNELGFDTRKIASAIGTAPIPPVRGAKRAMGVTNDATIYHGQIQLTMNAPEIKDYLEKIPSSKSKGYGKPFNDIFKEAGYDFYKIDTSLFSPAEVIINELSDGSVYRVGAVNTDVTLKSFGLQ", "output": "Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+)."}]}
+{"id": "function_valid_4260", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSNSPIQAVIFDWAGTIVDFGSFAPTSIFVEAFKQGFDFEIDLEEAREPMGLGKWDHIQAVGRIPAVDKRWNEKFGRSMTSEDIDAIYAAFMPLQKAKVADHADPILNAIEVVNGLKDKGIKIGSCSGYPREVMDVLIPVAADYGYKPDYVVATDDLPQGGRPAPFMALKNVIELNVTDVNACIKVDDAAPGIDEGHNAGMWTVGLLLSGNEAGLTFEEYQAADEATLNAAREKARAKLLKSSPHYLIDTIADFPEVVADIERRLAAGERP", "output": "Involved in phosphonate degradation."}]}
+{"id": "function_valid_4261", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSNVLELTIPASTANLGVGFDSIGMALDKFLHLSVKETSGTKWEYIFHDDASKQLPTDETNFIYHVAQQVASKYSVDLPILCIEMRSDIPLARGLGSSASALVGAIYIANYFGDIQLSKHEVLQLATEIEGHPDNVAPTIYGGLIAGFYNDVSKETSVAHIDIPDVDVIVTIPTYELKTEASRRALPQKLTHSEAVKSSAISNTMICALAQHNYELAGKLMQQDGFHEPYRQHLIAEFDEVKTIASQHNAYATVISGAGPTILIFSRKENSGELVRSLNSQVVSCHSELVDINISGVKERIVYQ", "output": "Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate."}]}
+{"id": "function_valid_4262", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKKTLLASSLAVGLGIVAGNAGHEAHASEADLNKASLAQMAQSNDQTLNQKPIEAGAYNYTFDYEGFTYHFESDGTHFAWNYHATGANGANMSAQAPATNNVEPSAVQANQVQSQEVEAPQNAQTQQPQASTSNNSQVTATPTESKASEGSSVNVNAHLKQIAQRESGGNIHAVNPTSGAAGKYQFLQSTWDSVAPAKYKGVSPANAPESVQDAAAVKLYNTGGAGHWVTA", "output": "Is able to cleave peptidoglycan and affects clumping and separation of bacterial cells."}]}
+{"id": "function_valid_4263", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MHVKKGDKVMVISGKDKGKQGTILAAFPKKDRVLVEGVNMVKKHSKPTQANPQGGISNQEAPIHVSNVMPLDPKTGEVTRVGYKVEDGKKVRVAKKSGQVLDK", "output": "One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.; "}]}
+{"id": "function_valid_4264", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGQKVNPIGLRLGINRNWESRWFPTKQSLPENIGEDYKIRAFLKKKLYYAGISQILIERTAKKLRVTVVAARPGIIIGKKGQDVENLKNEVSKLIGKEVNVNIKEERKAQASAQLAAENVAMQLEKRVAFRRAMKKVIQGAQKSGAKGIKISVAGRLGGAEMARTEWYLEGRVPLHTLRAKIDYGVAEAHTTYGNIGIKVWIFKGEVLQKGVQPEKTEEEAPKKTRRARRGK", "output": "Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation."}]}
+{"id": "function_valid_4265", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSMTDNVADMLTRIRNAYKSKLINVSFPSSKIKISILDVLQKEGYIKDYITTQKNNISYTEVALKYSVNGDASICEIHRVSKPGKRVYSPIKDLKGYYNNMGIYILSTPYGVMSDREAHIKNVGGEVICKVF", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit."}]}
+{"id": "function_valid_4266", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MHVKKGDKVVVISGKDKGKQGVILAAFPKNDRVLVEGINLVKKHSKPTQANPQGGISEQEAPIHVSNVMPLDPKTGEVTRVGYKVEDGKKVRVAKKSGQVLDK", "output": "One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.; "}]}
+{"id": "function_valid_4267", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MARIAGIDIPREKRVEIALTYVYGIGLTRSKLILANTGVNPDTRVKDLSDSDVQKLRGATEEFTLEGDLRRKEGMALKRLQDIGCVRGRRHRMSLPVRGQRTRTNARTRRGSRKTVAGRKK", "output": "Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites."}]}
+{"id": "function_valid_4268", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSKVVVCAMYKFVTLAEFEKLQSPLQKVMETSGVKGSLLLAQEGINGTVAGSQSAIDNLLAWLATQPGLDNIVYKLSFDDVMPFYRTKVKLKKEIVTMGVEGIDPKKVVGTYVKPKDWNQLISDPEVLLVDTRNDYEVQIGTFKDALDPKTKTFREFPDYVKQNLDPAKHKKVAMFCTGGIRCEKSTAYLKEQGFDEVFHLEGGILKYLEEVKLEESLWQGECFVFDNRVAVDHNLEKGQYAQCNACRMPITADEMALDSFVQGVSCLHCIDNISEKQRQRFIERERQVQLSKLRGEAHIGSDVSQVIQTRRAKKDRLKKAQHDKSA", "output": "Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs."}]}
+{"id": "function_valid_4269", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MFWSKKPLDLPTPETALKGRPDAIPTARLHHVNQNPLKGPYPDGFRTAIFALGCFWGAERAFWRTPGVWVTAVGYLAGLTPNPTYEEVCSGRTGHTEGVLVVYDPAVISYADLVKLFFESHDPTQGMRQGNDVGTQYRSGIYTSDPQEKAVAEAVKASYEAALKAKGFGPITTEIIDGGPFYFAEDYHQQYLSKNPGGYCGLGGTGVSCPIGVGVAAQ", "output": "Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine."}]}
+{"id": "function_valid_4270", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MARPKIALIGAGQIGGTLAHLVALKELGDVVLFDIADGTPQGKALDIAESGPVERFDASLKGTTDYADIAGADVCIVTAGVPRKPGMSRDDLLGINLKVMKSVGEGIAANAPDAFVICITNPLDAMVWALQQFSGLPKEKVVGMAGVLDSARFRHFLAEEFNVSMKDVTAFVLGGHGDTMVPLTRYSTVAGIPLPDLVEMGWTSQEKLDAIVQRTRDGGAEIVGLLKTGSAFYAPAASAVEMAEAYLKDQKRLLPCAAYCDGEFGLNDMYVGVPTIIGAGGIEKVVDIKLGKDEQAMFDNSVNAVKGLMEACKGIDDSLV", "output": "Catalyzes the reversible oxidation of malate to oxaloacetate."}]}
+{"id": "function_valid_4271", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MARSRFDTGSGPSQRQLRVGELIRRTLSSVLNQGDIHDPDLNRMSITVGEVRTSPDLKVATAYVLPLGGHGAQDALDALRRNRHELRRAVSKELTLKFSPELRFQIDETFDRMDETRRLLSQDHVRQDLDKPDED", "output": "One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA."}]}
+{"id": "function_valid_4272", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLQPIGDRVIVKVKDEEEKTVGGIVLASNAKKKPTEGEVVAVGEGAYASNGEKIPMSVKKGDVVLYDRYSGTNVEYEGEKYLVLHEKDILAIAK", "output": "Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel."}]}
+{"id": "function_valid_4273", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKCPKCNSTQSKVVDSRHADELNAIRRRRECENCGTRFTTFEHIEVSQLIVVKKDGTREQFSREKILNGLVRSCEKRPVRYQQLEDITNKVEWQLRDEGHTEVSSRDIGEHVMNLLMHVDQVSYVRFASVYKEFKDVDQLLASMQGILSENKRSDA", "output": "Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes."}]}
+{"id": "function_valid_4274", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIQITVVQIDNYGPWTVTPNPRRESDLQALQSRLYCDMNLQFGAHRGLAFYTRFDNIIAITNGIDLETHKRIQNSVKNRYPFTVSMAVASAETAYEAQKLATETIQEYGSAQDDVRKEVLDVANEFVSNGYVQLAHVDINDITGKLTDLETAYDTYLSVQMTKLKLMEELKKYDSMGFFIGGDNFMCPCNGMSEKDFLCMFEDIKESCGIDLKAGIGIGKTAEDASNLADIGLEVIREGKTDFQVYTLKQEIEERKDVTYNYMCPI", "output": "Catalyzes the formation of 2-amino-5-formylamino-6-ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity."}]}
+{"id": "function_valid_4275", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPKEDIHPTWYPDAKVICNGEVVMTTGSTQPEIHVDVWSGNHPFFTGTQKILDTEGRVDRFMRKYGMADSENDSTDKKKTTNEKKVSDSPSKES", "output": "Binds the 23S rRNA."}]}
+{"id": "function_valid_4276", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKVLVLGGGVIGVTSAYYLARAGAEVTVLDRQDAPASETSFANAGQVSPGYSTPWAAPGIPLKALKWMLQEHAPLAVRLDGSLFQLRWMAQMLRNCSAQRYAVNKERMMRVAEYSRSCLQQLRADTGIAYEQRTGGTLQLFRTQAQLDAVERDVAVLRECAVPFELLDRDQLAQVEPALAQARDRLTGGLRLPKDETGDCHRFTNELARIATGLGVELRFNQNVDGLVVEGGRIAGVRVNGELLTADRYVMAFGSYSRQALEPLGLDLPVYPVKGYSLTVPLGNPALAPQSTVLDETYKIAVTRFDDRIRVGGMAELGGFDLRLDPRRRATLELVVNDLFPGGDVARASFWTGLRPMTPDGTPIIGATRYANLFLNTGHGTLGWTMACGSGRLIADLITGRSPEISTDGLALDRYTHRPARHLGGSSTPVSA", "output": "Oxidative deamination of D-amino acids."}]}
+{"id": "function_valid_4277", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTDSLIAIVPAAGVGQRAGRPDLPKQYRLLAGQPMLRWAVAALLADARIGQVRVAVSPGDERAGAALAGLPRTVCRPCGGPTRAATVAAALADSNAADSDWILVHDAARPGLPPDALARLIDACLADAVGGLLALPVADTVKAGGPRVRATLDRDGLWLAQTPQMFRAGVLRAALAAAQAGGGTVTDEASAIEAAGHAPLLVPGAMRNFKVTWPDDFELMEKWL", "output": "Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP)."}]}
+{"id": "function_valid_4278", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSQSAVSFQISPVSKAQDPLIQQQIDLKTKPPGALGQLESLALQIARVQATDSQQTDQPQNTVLKIVHPTMLVFAGDHGIAAEGVSIAPSEVTRQMVQNFAHGGAAINVFCRQVGFRLEVIDCGILTPVEGVEGIIDQRLGAGTGAIHLEPAMALETVDKGFAMARDLIERHHQAGCNLVAFGEMGIGNTSAAAAIMAAIMQLDVIDCVGRGTGINSETLERKLMLIELALLLHQSALSGPKSVLACLGGFEIVQMTGAMLAAAERKMLVVVDGFIATAAALVAVQIAPNVRDYLIFAHQSDEQGHLRMLEFLQAKPLLSLGLRLGEGTGAALALPLIQASVNFYNQMASFSDAGIEAVV", "output": "Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB)."}]}
+{"id": "function_valid_4279", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSETKNVRTLQGKVVSDKMDKTVTVLVERKVKHPLYGKIIRLSTKIHAHDENNQYGIGDVVVISESRPLSKTKSWVVSELVEKARSI", "output": "One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA."}]}
+{"id": "function_valid_4280", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSRTIFCTYLQRDAEGQDFQLYPGELGKRIYNEISKDAWAQWQHKQTMLINEKKLNMMNAEHRKLLEQEMVSFLFEGKDVHIEGYTPEDKK", "output": "Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes."}]}
+{"id": "function_valid_4281", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSNETVLPLQFTEAAAKKVKLLISDEENPNLKLRVYITGGGCSGFQYGFTFDDQVNDGDMTIEKQGVELVVDPMSLQYLVGGAVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI", "output": "Required for insertion of 4Fe-4S clusters for at least IspG."}]}
+{"id": "function_valid_4282", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSNHDQLHRYLFANHAVRGELVSVNETYQQVLANHDYPPAVQKLLGEMLVATSLLTATLKFDGDITVQLQGGDGPLTLAVINGNNRQEMRGVARVKGEISDDSTLQEMVGNGYLVITITPAQGERYQGVVALEGETIAACLENYFMQSEQLPTRLFIRTGHVADKAAAGGMLLQVLPAQERNEDEFDHLAQLTATIKAEELFTLPANEVLYRLYHQEEVTLYEPQNVSFRCTCSRQRCADALVTLADDDVTEMLEQDGNIDMHCEYCGNHYLFDAVDIATLKNGNSASSEQIH", "output": "Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress."}]}
+{"id": "function_valid_4283", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEPVSTITGKAVVLPVENIDTDQIIPARFLKVTDRSGLAAGLFEAWRYQADGTPNPDFPLNRPEAAGATILISGRNFGCGSSREHAPWALQDYGFKAVLAPSFADIFRSNSLKIGLLPVTIDQAVYDELVARYAADPQMHLTIDLATQTVTLPDGRQVHFPIDAFSKYCLLHGVDQLGFLLQQEEAIIAYEASHPQPVTTR", "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."}]}
+{"id": "function_valid_4284", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSTNQETRGFQSEVKQLLQLMIHSLYSNKEIFLRELISNASDAADKLRFKALSNPALYEGDGELRVRVSFDETLGTLTISDNGIGMNREQVIDHLGTIAKSGTKEFLNSLGTDQAKDSQLIGQFGVGFYSAFIVADKVTVKTRAAGETQAVLWESAGEGDYTVADIEKATRGTDVILHLREEEKEFLSEWRLREIIGKYSDHIGLPVEIQTTEYNEEGKASGQKWEKINKAQALWTRSKNEISDEEYQEFYKHLSHDYNDSLIWAHNKVEGKQEYTSLLYVPAKAPWDMFNREQKHGLKLYVQRVFIMDDAEVFMPNYLRFMRGLLDTNDLPLNVSREILQENKITASLRAALTKRALQLLEKLAKDDQAKYQTFWNEFGLVLKEGVGEDFANKQQIASLFRFASTQTDSSEQTVSLADYVGRMKEGQKAIYFLTADSYVAAKNSPHLELFNKKGIEVLLLSDRIDEWVVGHLTEFDGKPLQSITKSDLDLGDLADKEQEESQKAQQAEFGSFLERAQSYFGERVKKVVLTHRLTDTPAVVSTDNDEMTTQMAKLFAAMGQKAPEVKYTFELNPDHQMVKKIADLTDETEFNDWIELLFEQALLAERGSLENPAAFIKRMNKLLG", "output": "Molecular chaperone. Has ATPase activity."}]}
+{"id": "function_valid_4285", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKVIITVNYEEMSKKAAEIVKKQIKEKPNTVLGLATGSTPLGMYKHLIEMYKRGEIDFSNVITFNLDEYIGLSPDHPQSYHYFMFHNFFNHINIKKENVHIPNGIAEDLEEECRKYEEEIEKAGGIDLQILGIGINGHIGFNEPDESIETKTHVVTLTEKTINANKRFFKSAEEVPRKAITMGLGSIMKAKKIVLLASGKNKAEAIKETIKGQLTTKVPATVLALHHDVTIIIDKEAASLIPDEDLKEIEVIV", "output": "Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion."}]}
+{"id": "function_valid_4286", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MIKEAIKIQGTKEGLVIVLEEDVDIETLKEKIVNRIEKSLKFFEGATLTVRVKSLSVKEEKLQELKDVIFEKYGIEVRIKNFQEKHIKNVTDDEIFNGLEEGITKFHKGTVRSGQVVKYHGNLVIIGDVNPGGLVQAAGNIVVMGTLRGIAHAGFTGNKEAVIVASSLRAMQLRIANVISRAPDKDDASDYPEIAVVKKGKIIVKPLYHLNDLW", "output": "Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization."}]}
+{"id": "function_valid_4287", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEEQGTGIRVEALSAEFAAQAAAWAERLELPLHDEAADFAVQVGADGLQIQQLGPQAPGPVRVDFVEGQAAHRRQFGGGNGQMIAKAVGIAQGVRPQVLDATAGLGKDAFVLASLGCQMTLIERQPLIAALLEDGLARARADEEVGAIVGRMRLLTGNAIERMRAWEGEPPQVIYLDPMFPHRDKSALVKKEMRVFRPLVGDDLDAPALLEAALALASHRVVVKRPRKAPIIDGPKPSHSLEGKSSRYDIYPKKALKA", "output": "Specifically methylates the guanosine in position 1516 of 16S rRNA."}]}
+{"id": "function_valid_4288", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSTTTSLIIAILAGILGIVIGFFFRKSLAEKKIRSAEDYAVKIIEDANKDAETKKKELLVEAKDEIFKMKSDLDRENKSRLKEISRQEDRLNSKEENLERKNASLEKKHKKLDSELKKADDMQLKIQSLIDEKELELEKVAGLTSDEAKNIVLERVKTETIREQAAIIKEIESKTKEESEKFAREIISTSIQRYAADQVAESTVSVVNLPNDDMKGRIIGREGRNIRAFETLTGVDLIIDDTPEAVVLSAFDPVRREIARIALEKLIVDGRIHPTRIEEMVEKARKDVDNTIREKGEEACDETNVHGLHPELIKILGKLHYRTSYGQNVLKHSIEVSNIAGMLASELGVNVKLAKRGGLLHDLGKAIDHEIEGPHVELGVNAAKRFKEPKDVINCIEAHHGDVEPTCIESILVQSADAISAARPGARRESMENYIQRLENLEQIANSFDGIESSYAIQAGREIRIMVKPDVIDESSMVILAKDVAHKIESELEYPGQIKVNVIRENRVSDYAK", "output": "Endoribonuclease that initiates mRNA decay."}]}
+{"id": "function_valid_4289", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSRRRGKVEPRHIEGDPKYNDKVISKFINCLMVDGKKSVAESVFYDALEVIAKKTGQDPFAVFQEALENAKPQVEVKSRRVGGVTYQVPIEVRPERRLALGIRWLIKYSRGRNEKSMKNKLAAEFMEAQKGTGSAIKKKEDIRKMADANKAFSHYRW", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."}]}
+{"id": "function_valid_4290", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MALLIEDKKQIVAEVSEVASKAFAAVVADYQGLSVEQLTTLRVEARKLGVTTRIVRNTLAKRAFQGTQFDILNDNLVGPTILGFSTSEDDMGAAARLFEEFAKTNKAFELKAAAFDGKVYQGADVSVIANLPNQEKALTMLASVLQAPISKLGRLITALKEKNESEAA", "output": "Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors."}]}
+{"id": "function_valid_4291", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSDDDVNEFAKNLLSAKRELTYCSVCGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHGLYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLLKPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL", "output": "May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO."}]}
+{"id": "function_valid_4292", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MARYIGPKCKLSRREGTDLFLKSGVRALESKCNIEAAPGIHGQRRGRQSDYGTQLREKQKVRRIYGVLERQFRGYYQAAASKKGATGENLLQLLECRLDNVVYRMGFGSTRSESRQLVSHKAISVNGKTVNIPSYQVRPGDVVAVREKSSNQLRIVQALELCAQRGRVEWVDVDSAKKSGVFKNVPARGDLSADINENLIVELYSK", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; "}]}
+{"id": "function_valid_4293", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFQDNPLLAQLKQQLHTQTPRVEGVVKGTEKGFGFLEVDGQKSYFIPPPQMKKVMHGDRIIATLHTDKDREIAEPETLVEPFLSRFVGRVQRKDDRLSIVPDHPLLRDAIQCRPVRELTHSFQNGDWAVAEMCRHPLKGDRAFQADLTAFITNGEDHFVPWWVTLARHNLEREAPAMVESALNDAELEREDLTALNFVTIDSASTEDMDDALFVQDNGDGSWLLTIAIADPTAYVVENSELDLTARKRAFTNYLPGFNIPMLPRDLSDNLCSLRPNERRPVLVCRVTITEEGTLSNDIRFSAAWVESKAKLVYDDVSDWLEGNNRWQPQDTAIAEQITLLKRICDARSNWRQQHALVFKDRPDYRFLLGEKGEVLDIIVEHRRIANRIVEECMIAANVCAALALREHLGFGIYNVHTGFDPALVEQAASVLKANGVGADPQALLTLPGFCELRRHLDALPTQFLDSRIRRFQTFAEISTVPGPHFGLGLEAYATWTSPIRKYGDMVNHRLLKAIITGQQAEKPQEEITVQLAERRRLNRMAERDVGDWLYARYLQPQAGTDTRFTAEIIDITRGGLRVRLLDNGAVAFIPAPFIHAVRDEVVCSQETGTVQIKGETVYSQSDKIEVRIAEVRMETRNVIARPVA", "output": "Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction."}]}
+{"id": "function_valid_4294", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQVKSHKPSKQRKYLYNAPIHHRGKIMSAPLSEELKSKYGINSIPIRKGDRVKVMRGDYRGTEGEVISVDRKRYRIAVKGIVRRKADGTEVPVPIHPSKVVITKLYLKDEARKRLLERKGVKVEEIVEESE", "output": "One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.; "}]}
+{"id": "function_valid_4295", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAAPKSTATRARRGRRVVKKNVTQGHAYIKSTFNNTIVSITDPKGHVISWASSGQVGFKGSRKSTPFAAQLAAESAARKAMEHGMKKVDVFVKGPGSGRETAIRSLSTAGLEVGTIADVTPQPHNGCRPPKRRRV", "output": "Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome."}]}
+{"id": "function_valid_4296", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQDQQQVIHKAQPWHGKVGLIYGQRQGKTEMQRCFTQAPFRIQRPFYPEGNRVCHTVLLHTAGGIVGGDRLSLDLELKPESHVFLTTAAANKIYRTNGETAQQDGIIHQAPGSILEYFPQEMIIFDGAEYHQSLRVNLAPGAVWCGWEVLRFGRTARGEKFISGNWRGLTEIWQDDELLWGDRQWLPGHPEVFAAWNGLNNQPVVGSLALVGLEISEAQMAELRQTMATIQQGLGGITQLPKGVLCRYRGPSSTEVKRWFISLWQNWRSLYSPQPPTLSRVWQTY", "output": "Required for maturation of urease via the functional incorporation of the urease nickel metallocenter."}]}
+{"id": "function_valid_4297", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKNADRGVAAELDGSDLRVAIVQARFNAAITEQLASSCIAELEALGVLAKHIKHVTVPGALEVALALQALAEQKDHDALIALGCIIRGETYHFELVANESGAAVTRVSLEHGVPIANAILTVENEAQAWARADEKGRDAARVAVEMANLMEDLS", "output": "Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin."}]}
+{"id": "function_valid_4298", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQPDRDTLLAGAQALGCPLSDTQADALLAYLGLLQRWNQVYNLTAIRDPKQMLVQHLLDSLAVIAPLNRVAGSAPLRLLDVGSGGGLPGVVIAVLRPDCQITCVDTVAKKATFIRQVTAELRLPQLVARHARVEQLTDGPYSVITARAFASLADLVKLTRPLLAPGGCWMAMKGQHPQAEIDALDADINVFHVEQLSVPGLDAERRLVWMRPRSVASS", "output": "Specifically methylates the N7 position of guanine in position 527 of 16S rRNA."}]}
+{"id": "function_valid_4299", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAEAKALPRFKKLYQDNIRKALLEEFKYDNEMQIPRITKVVLNMGVGEATGDSKKPAVAAEDLAMIAGQKAVVTRARNSIATFKLREGMPIGAKVTLRQDRMYEFLDRLITIALPRVRDFRGLNPKSFDGRGNYAMGIKEHIVFPEINYDKVDQIWGMDIIVCTTAKTDDEARSLLRAFNFPFRQ", "output": "This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs."}]}
+{"id": "function_valid_4300", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MALTLTDVKRIAHLARLELADADAEHTLVQLNDFFGLVEQMQAVDTSGIAPLAHPIEQIEDVALRLRNDVVTETVEREAFQRPAPAVQDGLYLVPKVIE", "output": "Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)."}]}
+{"id": "function_valid_4301", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNVKDFDFYLPEELIAQHPLEKRDTSRLMVLDKETGEISHKNFYDIIDYLNEGDTLVLNNTRVMPARLIGEKEGTGGKIEFLLLKRVEKDRWECLAKPGKSARVGRRFTFGDGKLKAEVVEVKDNGNRIVEFYYEGIFEEVLDSLGEMPLPPYIHERLEDRERYQTVYSKENGSAAAPTAGLHFTEELLHKIKDRGINIAYVTLHVGLGTFRPVKVDTIEDHEMHSEYYHLSKEDAEVINATKKRGNKVISVGTTSTRTLETIADEDGNVKETNGWTNIFIYPGYKFKVVDRLITNFHLPESTLIMLVSTLAGKEHVMNAYEEAVKEKYRFFSFGDAMFIK", "output": "Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)."}]}
+{"id": "function_valid_4302", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTEPTPAVPETDDLAEPRLVIEPGVAARFCAVAEPVLMAMGYRLVRIKVSGDAGCTVQIMAERPDGTMLIDDCEAASRALSPVLDVADPIDRAYRLEISSPGIDRPLVRRSDFARYAGHLVKIEMAVPHQGRKRYRGLLDGVEGDAVRVQREGATKDEDPLVLLPMHDIGDARLVLTDELIAESMRRGKQAERDLKQSLGLAPEPPPHAKRSDPKKSHAPKRGPKAAKAPTKPKPQNTKQHRLAADKARRGEIDTSEGD", "output": "Required for maturation of 30S ribosomal subunits."}]}
+{"id": "function_valid_4303", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKPLIALVGRPNVGKSTLFNRILRQKSAIVDPTPGVTRDRHINPGEWQGKQFLLMDTGGYAPENDSLSVAMLDQTMRAIADADAIIFMVDARSGLTYLDLDIAKILKQTFSDKKIFFAINKVDNPQLALEAAAMVRSGFTEPYLISARDGGGVADMLDDILETLPCPESEDEELDDDSIKLAVLGRPNVGKSSLVNALLGTDRQIVSDVPGTTRDAIDSVLKRNGKEYILIDTAGLRKRTKIDPGIEYYSSLRTERAIERCQVALVLLDAQLGLESQDMKIIHMAIERKKGVLILVNKWDLVEKDSKTSKKFTDNLMMQLGNIGYIPIIFTSALTKKNCYRAIDTAAQIAINRRQKISTSNLNRFLQEALAMRHPASKSGKELKIKYMTQIEAGHPVFAFFCNDPQLLENNFKRFLEKRLRESFDFEGLPITMRFLRK", "output": "GTPase that plays an essential role in the late steps of ribosome biogenesis."}]}
+{"id": "function_valid_4304", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQLVIVAVGHKMPGWIETGFSEYAKRMPPELRIELREVKPETRSSSNNAATVMQREAARIEAVLGSLSKQCRIVALDERGRDFTTVQLAAQLTDWQREGGDVAFLIGGADGLDPALKARASTLIRLSSLTLPHGMVRVLLAEQLYRAWSVTQNHPYHRA", "output": "Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA."}]}
+{"id": "function_valid_4305", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQCARSSAGDCHSCGWLSLAYSEQINQKQHNLLDLLPKNYAFTQLAPVESQQVKFRNKAKMVVSGSVEKPILGLRKPEGEGVDLCQCPLYPASFEPVFPILKTFIAKAGLVPYNVERRRGELKFILLTESRHNHSMMLRFVLRSEKKLAQLRQALPWLQAQLPQLAVISVNIQPVHMAILEGEQEIVLTEKTFLDEYFNEIPLHIRPKGFFQTNPDVAASLYATAGHWVKELQINRLWDLFCGSGGFGLHCAQKNTELTGIEISPEAIECARLSANELGLEHVEFQALDSTGFALAKESVPELVLVNPPRRGIGETLCDYLNSMKPRFILYSSCNAQTMAKDIQQLSHYRIDRVQLFDMFPHTAHYEVLTLLVLQQS", "output": "Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA."}]}
+{"id": "function_valid_4306", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPDQPLNRTTIPEKKLSNLPTCPGVYQFKNNQGTIIYVGKAKNIRSRVRSYFREGPHISGKTKVLVNHIADIDIILTSSEVEALILENNLIKDLKPRYNINLKDDKTYPYLVITNEAFPRILITRQVKRDGSTYFGPYTEARQLRSVLDLISTIFPVRKCKLKLTKENIESGRFSVCLNYHIHTCKGPCEGKQREEDYLRMIEEIKGLLKGKTGALIRTLSAEMHRYADELRFEEAAELKIQIEGLRKYTERQKVVSKDPVDRDVFGIAQHQDDACGVIFKIREGKLLGSQRMYFSNVDDEQHETLLRKCLEKYYLETPDLIPQEIFLPLPIDDDEVMALRELTGDINLRFIVPKIGEKAKLVAMCIDNARHHLEEYLIEKQKRGELSRIVPALQALQETLHLSRQPERIECFDNSHFQGTDYTSSMVCFVGGKPRKSDYRKFKLNSFEGSDDYAAMQEAVTRRYSGSLQDELPLPDLIVIDGGKGQVNTAWKVLQELGLEIPVIGLAKRLEEIFLPNTPDPYNLAKTSPALKLLQQIRDEAHRFAITYHRKLRTKRTIQTGLTDIAGIGEKSAMKLLEHFGSIEQIAKAEKEEILAVTGPKTAEAILSYFRKKQP", "output": "The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision."}]}
+{"id": "function_valid_4307", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFYWILLALAIATEITGTLSMKWASVGNGNAGFILMLVMITLSYIFLSFAVKKIALGVAYALWEGIGILFITIFSVLLFDEALSTMKIAGLLTLVAGIVLIKSGTRKPGKPVKGAARATI", "output": "Catalyzes the excretion of spermidine."}]}
+{"id": "function_valid_4308", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLENMFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSLATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLGALDYLFVASKPFAERYFPNGVTRSSLLKAPAVAFDHLDDMHQAFLQQNFDLPPGSVPCHIVNSSEAFVQLARQGTTCCMIPHLQIEKELESGELINLTPGLLQRRMLYWHRFAPESRMMRKVTDALLEYGHKVLRQD", "output": "Controls the transcription of genes involved in arginine and lysine metabolism."}]}
+{"id": "function_valid_4309", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNKFSSVWVFSDTPSRLPELMSGAQAVGEKVNAFVLNEADSATACHLGADHVWLLSGKPEDRMIEDYAAAMAETIRQHSEGGAVLLPNTRRGKLLAAKLGYRLSAAVSNDASDVSLQDGKAAVKHMVYGGLAIGAETIASPFAVITLSSGTFDAQQPDASRSGEMHTVQWQAPATAVTRTATQARQSNSVDLDKARLVVSVGRGIGSKENISLAEALCQTIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANGAQTIFAINKDKNAPIFQYADFGIVGDALKILPALTAALAR", "output": "Required for anaerobic carnitine reduction. May bring reductant to CaiA."}]}
+{"id": "function_valid_4310", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MDEQRSKALSAALSQIDKQFGKGAVMRLGDHNAIKDIEVYSTGSLGLDLALGVGGLPRGRVVEIYGPESSGKTTLTLHAIASCQAAGGTAAFIDAEHALDPGYAHKLGVDLENLLISQPDTGEQALEIADMLVRSGAVDLIVIDSVAALTPKAEIEGDMGDSHVGLQARLMSQALRKLTANISRTNTLVIFINQIRMKIGVMYGSPETTTGGNALKFYASVRLDIRRIGAIKKSDEVVGNDTRVKVVKNKVAPPFREAEFAIYYGEGISRLSELVDLGVKFDIVEKSGAWYSYQGERIGQGKDNARQYLKEHPELAANIEQRIRAAAAGHPLAFAEEVAEPAAVG", "output": "Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage."}]}
+{"id": "function_valid_4311", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKSSLKPVEKYAYSIFEIAKEEKKLDLYKHNLETINSIIEEVPAFFEAVGDPARDRNERKQIVIKNLEGEIDIYLISLIDLLIDVKSIKLLKKIVLKALDFVNEALSVKKVLITTAYELTKNQIDRLVQSLKKKYACEKIEPIVVVDKSIIGGLSINFESQVLDNSLKTKLFNVVKKTN", "output": "F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.; "}]}
+{"id": "function_valid_4312", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MASTNFRPLHDRVVVRRVESEAKTKGGIIIPDTAKEKPQEGEIVAVGSGARDESGKVVALDVKAGDRILFGKWSGTEVKIDGEDLLIMKEADIMGIIG", "output": "Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel."}]}
+{"id": "function_valid_4313", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKSGAIKAAKKAGNVAADGVIKTKIDGNYGIILEVNCQTDFVAKDAGFQAFADKVLDAAVAGKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIGVLVAAKGADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDIAMQSGKPKEIAEKMVEGRMKKFTGEVSLTGQPFVMEPSKTVGQLLKEHNAEVTGFIRFEVGEGIEKVETDFAAEVAAMSKQS", "output": "Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome."}]}
+{"id": "function_valid_4314", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MIYDIIGDIHGCFHEFMLLTKKLGYVWENDVPIHPNGRKLAFVGDLADRGPQSLQVIDTVISLVQQNKAVYVPGNHCDKLYRFFLGRNVQVTHGLETTVAEWEQADEKTKTRIRTQFMKLYENAPLYAILDDGKLVIAHAGIRGDYIGKSNQKVKKFVLYGDITGEKHPDGSPVRRDWAKHYRGDALIVYGHTPVKEPRWLNNTVNIDTGCVFGGQLTALRYPEMETVSVPSTMPYVAEKFRPFD", "output": "Asymmetrically hydrolyzes Ap4p to yield AMP and ATP."}]}
+{"id": "function_valid_4315", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MYAIIETGGKQIKVEAGQEIYIEKLDVEAGETVTFDKVLFVGGENVKVGSPVVEGATVTAKVEKHGRAKKIIVFKYKAKKNNRKKQGHRQPYTKLVVEAINA", "output": "This protein binds to 23S rRNA in the presence of protein L20."}]}
+{"id": "function_valid_4316", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAKEKIRIRLKAYDHRILDQSAEKIVETAKRSGATVSGPIPLPTEKTVYTILRAVHKYKDSREQFEMRTHKRLIDIVSPTPQTVDSLMRLDLPSGVDIEIKL", "output": "Involved in the binding of tRNA to the ribosomes."}]}
+{"id": "function_valid_4317", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKYDIIGDIHGCLQEFQNLTEKLGYNWSSGLPVHPDQRKLAFVGDITDRGPHSLRMIEIVWELVIHKKVAYYAPGNHCNKLYRFFLGRNVTIAHGLETTVAEYEALPSHKQNMIKEKFITLYEQSPLYHVLDEKRLLVCHAGIRQDYIGRQDKKVQTFVLYGDITGEKHADGSPVRRDWAKEYKGTTWIVYGHTPVKEPRFVNHTVNIDTGAVFGGKLTGLRYPEMEIVSVPSSLPFVPEKFRPIS", "output": "Asymmetrically hydrolyzes Ap4p to yield AMP and ATP."}]}
+{"id": "function_valid_4318", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MRCPSCSHNGTRVLDSRPVDEGRSIRRRRECESCLSRFTTFERVEESPLIVVKKEGTREEFNKEKILRGLIKACEKRPVSLRQLEEVTQSVERELRNLGISEVKSDMIGEIVMEELRDIDDVAYVRFASVYRQFKDLNVFIEELKDILQKERE", "output": "Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes."}]}
+{"id": "function_valid_4319", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MISDKIKLTAKDILEKEFKTGMRGYQQEEVDKFLDMIIKDYEAFHKEFEQLKQQNARLKRELEEQKLAATQVPQQPVVQTPVAQPVYNNTNTDILKRLSNLEKAVFGSKLYE", "output": "Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation."}]}
+{"id": "function_valid_4320", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKVIASTLRKGNVVDKDGKLYVILTAENIHPGKGTPVTQLDMRRITDGVKISERYRTTEQVERAFVEDRDHTFLYQDGEGYHFMNPESYEQIAVPADVVGDAAPYLQEGMTVTLSTHNGVPLTIELPQRMTFEIVETEPVTKGQTASSSYKPALLSNGVKTSVPPHVSTGTRVVIMTADGSYVERAKD", "output": "Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase."}]}
+{"id": "function_valid_4321", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKAGYAEDEVVAVSKLGDIEYREVPVEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTESL", "output": "Acts as a radical domain for damaged PFL and possibly other radical proteins."}]}
+{"id": "function_valid_4322", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLENMFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSLATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLGALDYLFVSSKPFAEKYFPNGVTRSALLKAPVVAFDHLDDMHQAFLQQNFDLPPGSVPCHIVNSSEAFVQLARQGTTCCMIPHLQIEKELASGELIDLTPGLFQRRMLYWHRFAPESRMMRKVTDALLDYGHKVLRQD", "output": "Controls the transcription of genes involved in arginine and lysine metabolism."}]}
+{"id": "function_valid_4323", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK", "output": "Involved in pyrimidine catabolism. Catalyzes the deamination of 3-aminoacrylate to malonic semialdehyde, a reaction that can also occur spontaneously. RutC may facilitate the reaction and modulate the metabolic fitness, rather than catalyzing essential functions."}]}
+{"id": "function_valid_4324", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSGFQQHTGLVVPLDTANIDTDAIIPKQFLQKVNRIGFGKHLFHDWRFLDDAGQQPNPEFVMNAPRYKGASILLARENFGCGSSREHAPWALADYGIQVMIAPSFADIFYGNSINNQMVPVRLTEQEVDELFQFVEANEGAEITVDLEAMKVRANGKEYSFEIDEFRRHCLLNGLDNIGLTLQHADKISEFEAKIPSFLK", "output": "Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate."}]}
+{"id": "function_valid_4325", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLFLTQVREVVVSEVNIPLSFSDAAATRVQTLIAEEENPDLKLRVYITGGGCSGFQYGFTFDEKVNDGDTTIVNSGVTLVVDPMSLQYLMGGMVDYTEGLEGARFFVNNPNATTTCGCGASFSV", "output": "Required for insertion of 4Fe-4S clusters for at least IspG."}]}
+{"id": "function_valid_4326", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKQILNILPMFIFFIFYKFYDIFIASGSLIVISGLICIIHWIFYNEIDKISLFSFLSVFFFGSLTIFFHNSQFIKWKITIIYIIFSLVLLISQFFTRKPMIQRFLEKDIKISNIYWRKINFIWSLFFLFCAILNIYIAYYFSETIWVNFKVFGFTSLTFFLILITSIYINCKISKNK", "output": "Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis."}]}
+{"id": "function_valid_4327", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MANVVDQSKEQMKKSVESTKENFAGIRTGRANPALLNGIVVEYYGAPTPLKHVATIGVPEPRTLSVTPFDPSQANAVEKALRDSDLGASPRRNGSAILLTMPELTEDRRKEYVKLAKSKAEDGKVAVRNIRRKSKEAIDKAVKDGEMGEDEGDRLLKELDKVTKATTDELDALLEAKQKEIMEV", "output": "Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another."}]}
+{"id": "function_valid_4328", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKVAVLGAAGGIGQALALLLKTQLPAGSHLSLYDIAPVTPGVAVDLSHIPTAVEIKGFAGEDPTPALVGADVVLISAGVARKPGMDRSDLFNINAGIVRNLIEKVAATCPTALVGIITNPVNTTVAIAAEVMKKAGVYDKNRLFGITTLDVIRSETFIAELKGLNVADVKVNVIGGHSGVTILPLLSQVEGATFTDEEVASLTTRIQNAGTEVVEAKAGGGSATLSMGQAACRFGLSLVRGLQGEANIVECAYVDGGSEHAEFFAQPVLLGKNGIEKVLPYGEVSAFEANARDSMLDTLKGDIKLGVDFVK", "output": "Catalyzes the reversible oxidation of malate to oxaloacetate."}]}
+{"id": "function_valid_4329", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTSYTFSRELRLLTPAQFKSVFSNPIKASSAEITLLAIPNTEQHPRMGLTVAKRFVKRANQRNRIKRVIRDSFRLNQHDIPHLDIVVLVRNGVMEMENAEINKLIEKLWRKLSRRYNG", "output": "RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme."}]}
+{"id": "function_valid_4330", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSEALNELATYLTEVRGALISSSEIKYGELNVTTTAENVIALLTFLRDDAKCGFVNMTDICGVDWPQRPDRFDVVYHLLSPKKNLRIRIKVPVAEDQPVPSACGIYPGADWFERETWDMYGVLFTGHPDLRRILTDYGFEGHPLRKDFPTTGFVEVRYDDAAKRVVYEPVELKQEFRNFDFLSPWEGTDYVLPGDEKAKA", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_valid_4331", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSELTSLTIAEAREKLVSKDITAVELTDAYLGAIEAANGAINAYVTVTPEIARDMAKASDARLATGKAGALEGIPLGVKDLFATRDVHTQACSNILDGFKPKYESTVTQNLWNEGAVMLGKLNMDEFAMGSSNENSFYGPVVNPWRATGSEEKLVPGGSSGGSAAAVAARLCAGATASDTGGSIRQPAAFTGTVGIKPTYGRCSRWGIVAYASSLDQAGPIARDVRDAAILLKSMASIDEKDTTSVDLLAPNYEAAIGQSVKGMKIGIPREYRVDGMPEEIEALWQKGMAWLKEAGAEIVDISLPHTKYALPAYYIVASAEASSNLARYDGVRYGLRVDGKDIADMYEKSRAAGFGKEVQRRILMGTYVLSAGYYDAYYLRAQKVRTLIKRDFEQVFAAGVDAILTPITPSSAFAIGDKDLAADPVKMYLNDIFSVTLNMAGLPGLSVPAGLDAKGLPLGLQLIGKPFEEETLFKTAHVIEQAAGKFTPAQWW", "output": "Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)."}]}
+{"id": "function_valid_4332", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MASYGMGDLKKGLKIEIDGIPFKIVEYQHVKPGKGPAFVRIKIKSFIDGKVLEKTFHAGDKCESPNLEEKQMQYLYDDGENCQFMDTQTYEQVAISDEDVGEAKKWMLDGTMVDVLFHNGKAIGVEVPQVMELKIIETAPNFKGDTQGSNKKPATLETGAVVQIPFHVLEGEIIRVDTVRGEYIERANK", "output": "Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase."}]}
+{"id": "function_valid_4333", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEIVAENRKARFDYFVLQEYDAGMVLVGSEVKSLRQRKVNMGDAYVLEKDMELWIHNLHISEYNRSDRKNHKPLRVRKLLLRKREIHKIAGNIKVSGLAVVPLMIFFNNKGIAKIKIAIVKGKKLYDKREAIKTRDWQREKSRISRREV", "output": "Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation."}]}
+{"id": "function_valid_4334", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MASLKSIKKRIVSVKNTGQITKAMKMVSAAKLRRAQENVVAARPYAAKLGEVLGRLSRNQDADSSPLMIKRTTGKALLIVVTSDRGLCGGFNANLCKAAERFVKERGAEFTDLSIMTIGRKGYEFLKNRQKIRKNFGTVFSNLNYQTAALLAQEVIQGYLDEEFDEVFIIYNAFRSVMSQDITLEQLLPVTPPEAADEEYAPEYIYEPSKSELLGELLPKHIEVQIFKSLLESVASEHGARMTAMDSASKNANEMIGKLTLQYNRARQAAITTELMEIISGAESIKG", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex."}]}
+{"id": "function_valid_4335", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADAANVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGDFETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKMDGRQMFMQLAPISDKK", "output": "IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins."}]}
+{"id": "function_valid_4336", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRDPIETVMNLVPMVVEQTNRGERAYDIFSRLLKERIIFVNGPVEDGMSMLVCAQLLFLEAENPKKEINMYINSPGGVVTSGMAIYDTMQFIRPPVSTLCMGQAASMGSLLLTAGATGHRYALLNARIMVHQPSGGFQGQASDIERHAQDIIKMKRRLNEIYVKHTGRDYDTIERTLDRDHFMTAQEALEFGLIDKVVEARDVSADESK", "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins."}]}
+{"id": "function_valid_4337", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKTILVTGFDPFGGEIVNPAWESVKELGKIESDLYKVELRQIPTVFEKSIEHLYAAIEETKPDIVLCIGQAGGRGDIAVERVAINVNDARIPDNEGNQPIDTPIRENGPTGYWSTLPIKAIVHELKQKGIPASISQTAGTYVCNHLFYGLMHYLAEKKASVRGGFIHIPYLPEQAARQADQPSMALETIVKGLQLAIETTISHDRDIVMEGGQIS", "output": "Removes 5-oxoproline from various penultimate amino acid residues except L-proline."}]}
+{"id": "function_valid_4338", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MANIKSQQKRNRTNERARLRNKAVKSSLRTAVRAFREAAHAGDKAKAAELLASTNRKLDKAASKGVIHKNQAANKKSALAQALNKL", "output": "Binds directly to 16S ribosomal RNA."}]}
+{"id": "function_valid_4339", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MCDFMDYIQLAFYDASKWNRDNSYSRLTTTANALLDFSTPERLKVNLSSLSTPHFATTYTLGTVGLIDGSISYLFTTIPLHNTPSRSSLIPLRKLVPGYRQIYPPSIPIEYPTANDHSGIPAAVRSKADNPKMKPTLLHATLHLPPPTTLTGLFICRLSSTTQLSLAVCSSRAPASKSAPQATLLTQIFHDTGKYSSEFLFSTDNALLGFKGLWNFGPDPRKPTRGDPASQRSRPLLSLLSAGGEVYYSPVSSVVGLSTGLRFATLPAATENAHSAFPYTLTLTLTPLTGSMSTTYSLLASPNLAFSSRFGFNVYSWESEMVAGCELWRRSKSKSQNIYPSAVDNLAWARLKMGVPDTAVSVNPEHELSYFHKEGHNSSHASDSVIKVRVDQSWNIRALWEGRVKELLISAGVALGPASRSTLSYASPVAPGGLSSYGWKSVGVSVLYAS", "output": "Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria."}]}
+{"id": "function_valid_4340", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTFNPNIATHTLEAEGLRCPEPVMMVRKTIRTMLDGEVLLVTADDPSTTRDIPSFCRFMDHQLLGAQIDQLPYQYLIKKGLA", "output": "Sulfur carrier protein which probably makes part of a sulfur-relay system."}]}
+{"id": "function_valid_4341", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAERSQNLQDLFLNTVRKQKISLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHAISTIMPGQPLQMFENEEAAS", "output": "RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs."}]}
+{"id": "function_valid_4342", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSKLPLLPTTVIGSYPRPKWLRESIRLHKAGKISDEDLQEAFNDAVIAVLKDHYNAGVDVPTDGEVRRDEMVEFFAERIKGFKFYGPVRVWGTAYYRKPSVVSKIEYKKPMLVDEFTFAKSVSYTDNLKITITGPYTIAEWSYNEYYKNKKDLVFDLAKAINQEIKNLVEAGAKIIQIDEPALHTRREDVSWGVEAVNEAVKGVNAKLVMHICYGEYSFVAPYLNELKVDQINFAFKIYNYKPLELLKRYGFDKELGAGVIDVHNRRIETSEEVANDIRKILEYFTPEKVWINPDCGLKLLSRKIAYQKLVSMVEGTKVVREELKRKGYSVD", "output": "Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown."}]}
+{"id": "function_valid_4343", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSKVKKNDETLSEVLVDVNRVTKVVKGGRSFAFSAYVVVGDKAGRVGAGHGKAKEVNEARGKAKQAAKKRMMKVPLYQNRTIHHDVVGKSGAAKVILRRAKAGTGIIAGGSMRAIFDSLGVHDIVAKSIGSTNVYAMISATFDALNKLASPKSIAMRRDKKVNEISVKSADIQVNE", "output": "With S4 and S12 plays an important role in translational accuracy.; "}]}
+{"id": "function_valid_4344", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MLKYDVIVIGGGHAGVEAAAASARLGVPTLLITLKPENLGEMSCNPAIGGIAKGTLVKEIDALDGLMGYVIDQAGIHYKMLNETRGPAVWGPRAQADRKLYKKAMYQILTNYPNLDILYGKVEDIEIKSSKIEAVILNNGSKILCQKIILTTGTFLSGLIHIGQKKIPAGRVDEEPSYGLSNTLKQIGFKLARLKTGTPPRIDGRTIDYSKTILQPGDKIPRPFSELTNIVNVSQINCFITTTTSETHDIIRENLDKSAMYSGQIEGIGPRYCPSIEDKIVRFSTKSEHRIFLEPEGLDDYTIYPNGISTSLPEDVQHKLIKTIPGLENVKVLRPGYAIEYDYVDPREISVTLETKKIAGLYLAGQINGTTGYEEAAGQGIIAGINAALAVKDQAPFMLTRANSYIGVMIDDLTTFGTIEPYRMFTSRSEYRLSLRADNSDLRLTELGMNIGVVSEKRKKIFTKKCEDIEKIKSLLNTLSLTTSKLAKMGIQVAQDGTYKTVLDLFKIPNFNVEQAIKIFPMLKETQNNNILQLLYIEAKYASYLTRQHADINLFQSEEAQFIPKNLDYFKIPSISLEIQEKLSSHKPTTIGVARRIPGITPAAITAIIIYLKTKYSDGSST", "output": "NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34."}]}
+{"id": "function_valid_4345", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRTGIIAQKIGMTSVFNDKGERISLTLVKVDDCQVVGHKTLEKHGYNALVIGVKDKKISRVTKPMRQVFANAKISPKTKLKEFRISEENFIDIAASLEVDHFTAGQFVDITATTIGKGFAGSMKRHNFRGLEASHGVSISHRSHGSTGQRQDPGKVFKGKKMAGHMGCNQVTIQNLKIFAVDKERKLIMIQGSIPGHKNSYLSVKDAIKKISITV", "output": "One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit."}]}
+{"id": "function_valid_4346", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAFKKKFTPKKKFCRFCANKNLPVDYKRPDILKDFITDRGKIIARRITGTCAKCQRRLTLEIKRARQMALLYYTATHSAEHLKKM", "output": "Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit."}]}
+{"id": "function_valid_4347", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAKLQAEGLFDQQYKKPLPSPAHCVGVITSKTGAALHDILHVLKRRDPSLPVIIYPAAVQGDDAPGQIVRAIELANQRNECDVLIVGRGGGSLEDLWSFNDERVARAIFTSRIPVVSAVGHETDVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTRQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLERLQKRMSFALENQLKRTGQQQQRLTQRLNQQNPQPKIHRAQTRIQQLEYRLAETLRAQLSATRERFGNAVTHLEAVSPLSTLARGYSVTTATDGNVLKKVKQVKAGEMLTTRLEDGWIESEVKNIQPVKKSRKKVH", "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."}]}
+{"id": "function_valid_4348", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRPYAETMRKVIGHLAHGNLEYKHPYLEDRDVKRVGYLVVSTDRGLCGGLNINLFKKLLAEMKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAYDEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDTLLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQELTEIVSGAAAV", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex."}]}
+{"id": "function_valid_4349", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGDKTKVQVSKLKPGRYIIIDGEPCRIVNITVSSPGKHGSAKARIEAVGIFDGKVRSIVKPTSAEVDVPIIDKRVGQVIAITPDTVQIMDMETYELYDVPIETGVEDEVKDQLKEGITVEYWETLGRIQIKKVRGE", "output": "Functions by promoting the formation of the first peptide bond."}]}
+{"id": "function_valid_4350", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MYAVFQSGGKQHRVSEGQTVRLEKLDIATGEAVEFDQVLMVANGEEIKIGVPFVDGGKIKAEVVAHGRGEKVKIVKFRRRKHYRKQAGHRQWFTDVKITGISA", "output": "This protein binds to 23S rRNA in the presence of protein L20."}]}
+{"id": "function_valid_4351", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKTMFILALIALAATSVVAQLDTTCSQGYGQCQQQPQQQVNTCSALLQQCSPTPYVQSQMWQASGCQLMRQQCCQPLAQISEQARCQAVCSVAQVIMRQQQGQSFGQPQQQVQSFSQPQHQVPIEITRMVLQTLPSMCNVNIPQYCTTTPCRTITQTPYNIPMSATCVGGTC", "output": "Seed storage protein. Not integrated in the gluten polymer through disulfide bonds, unless incorporated by reduction and reoxidation during dough making. Increases dough strength and bread volume, but decreases dough stability when added into a base wheat flour (By similarity)."}]}
+{"id": "function_valid_4352", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKVTLIAILTCAAVLVLHTTAAEELEESQLMEVGMPDTELAAVDEERLFECSVSCEIEKEGNKDCKKKKCKGGWKCKFNMCVKV", "output": "Postsynaptic neurotoxin."}]}
+{"id": "function_valid_4353", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEKLTILLLVAAVLMSTQAMFQGGGEKRPKDKIKFLSKRKTNAESWWEGECLGWSNGCTQPSDCCSNNCKGRNCDIW", "output": "Inhibits voltage-gated ion channels."}]}
+{"id": "function_valid_4354", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MASYAVLGATGNCGSALIQLLLQRPDASIHAFCRNKPKLIGLLPEIEKSERVTIYQGSIKDTDLLTACLRGRRAVFMVLSSNINEPGFRVGRDANKAVIEVLRTLHREDSGSTGPPPKIILLSSATLDDTLSRKTPYLLRQILHMSASHIYNDLAETEKLLRAEQEWLTTVFVKPGALSVDEQRGHALSFVESDNPVSYLDLAAAMIEAADDTTDKYDMKNIGVVNTNGAARFPTGTPLCIATGLLRHFVPSLHPYLP", "output": "Oxidoreductase; part of the ergochrome gene cluster responsible for the typical purple-black color of the ergot sclerotia . The ergochrome gene cluster produces several ergot pigments including the yellow ergochrome secalonic acid and its derivatives, as well as the red anthraquinones endocrocin and clavorubin . The pathway begins with the synthesis of atrochrysone thioester by the polyketide synthase (PKS) CPUR_05437 (By similarity). The atrochrysone carboxyl ACP thioesterase CPUR_05436 then breaks the thioester bond and releases the atrochrysone carboxylic acid from CPUR_05437 (By similarity). The atrochrysone carboxylic acid is then converted to atrochrysone which is further transformed into emodin anthrone (By similarity). The next step is performed by the anthrone oxygenase CPUR_05434 that catalyzes the oxidation of emodinanthrone to emodin (By similarity). Emodin is further modified to yield monodictyphenone via several steps involving CPUR_05427, CPUR_05428, CPUR_05429 and CPUR_05430 (By similarity). The short chain dehydrogenase/reductase CPUR_05418 then catalyzes the C-5 ketoreduction to give the xanthone skeleton of the monomeric units . Ergochromes formation requires further dimerization steps of different xanthone units, probably catalyzed by the cytochrome P450 monooxygenase CPUR_05419 . CPUR_05425, CPUR_05426 and CPUR_05431 are unique to Claviceps, thus it is likely that they are involved in further modification of xanthone units or in their dimerization . The yellow ergochromes and the red anthraquinone pigments endocrocin and clavorubin are products from the same PKS derived precursors and the latter are likely shunt products in the pathway of xanthone biosynthesis . It is proposed that atrochrysone carboxylic acid released from the PKS CPUR_05437 can also be converted to endocrocin anthrone which is further oxidized into endocrocin by CPUR_05435 (By similarity). Endocrocin could be then modified to clavorubin, possibly by CPUR_05423 and CPUR_05431 . Clavorubin is the principal anthraquinone metabolite produced by the cluster with a much higher yield compared to endocrocin ."}]}
+{"id": "function_valid_4355", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKKIAWSLGILVTIGALCAIVWPSWYPSRPLVTTPSQADIQADQSSPRDLLEYFLSGLGETSLPVIQQQVQRYEQENQGLLIDSSLFAQYVQYKAALSELTLPQASGGLSTQEWWQLHQSLLDLQARYFSAEQQALFAEENRLRELAIEKRRIYEQYGQSEEAQRAWQALLLDQPDFIQRSEATAQLLPQLTQAGQGDTQQRYLARVALVGEQGAQRLAELDDSRATFEQQFQDYYQARAAILVRNELSASEQQTQIQQLREQHFAPEQWRRIDALERLKDNGE", "output": "May be involved in the folding of the extracellular lipase during its passage through the periplasm."}]}
+{"id": "function_valid_4356", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSIPFSNTHYRIPQGFGNLLEGLTREILREQPDNIPAFAAAYFESLLEKREKTNFDPAEWGSKVEDRFYNNHAFEEQEPPEKSDPKQEESQIPGKEEEASVTILDSSEEDKEKEEVAAVKIQAAFRGHVAREEVKKMKTDSLQNEEKEENK", "output": "Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates (By similarity)."}]}
+{"id": "function_valid_4357", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MFKRKSTAELAAQMAKLNGNKGFSSEDKGEWKLKLDNAGNGQAVIRFL", "output": "Binds preferentially to single-stranded DNA and therefore, destabilizes double-stranded DNA. It is involved in DNA replication, repair and recombination. Binds ss-DNA as the replication fork advances and stimulates the replisome processivity and accuracy."}]}
+{"id": "function_valid_4358", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNKSLKEIYYQDVIPGLIEQFNYTNIHQVLKITKITLNRGLGEASKNNKILEASIKEFELISGQHPLINKARKSVAGFKIREGMPVGISVTLRKKLMYTFLEKLIHLSLPRIRDFRGVSVKSFDGRGNYNLGIKEQLIFPEIEYDQVDQVRGLDISITTTAKTQQEGIALLRALGMPFNDN", "output": "Binds 5S rRNA, forms part of the central protuberance of the 50S subunit."}]}
+{"id": "function_valid_4359", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEQMRQDIIELKQNDKSQEQRISLLERTSDRHDQQIQAVTESLSKIHENTTWIKRTITGAIISTLSTVVVGGILTIVWNLVKN", "output": "Probably functions as a holin together with holin-like protein 26. Accumulates harmlessly in the cytoplasmic membrane until it reaches a critical concentration that triggers the formation of micron-scale pores (holes) causing host cell membrane disruption and endolysin escape into the periplasmic space. Determines the precise timing of host cell lysis."}]}
+{"id": "function_valid_4360", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNLMLITFNEFKTGISLNDTRAEHLVKILKLKDNDKFKFGILGEKNIYHCIYKKDKKLFFKKIFKVGESNKLKKLYVLIGMIRPIVAKRIIKELASIGTYKIIFFNTELTEKSYLNSKIFKNNDCEKHLIAGAMQGKITYLPKIKIIKNLKESLKYIQQENFEIKILLEKNSEKNLIDIEQINNAVIIVGPERGFTEKEKQLIAQYNFSPYSISTNTLRTETATIAASIITASKLINM", "output": "Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)."}]}
+{"id": "function_valid_4361", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "SRTLIKSKLWVGPEIQKEMKLVAPNLDLTVDYGWLWFLSQPLFKLLTIINSIINNWGFSIILITFIMKIITYPLTKSQYVSMSKIRALQPKIKEIKEAFSDNKQRISQEMIILYKKEKINPLGGFLPVFIQMPVFLSLYYMLIGSVELRHAPFVLWIKDLSSQDPFYVLPIIMGLTMFFIQKTSSNNISDPIQKKIMNFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQKFIFSNFKSN", "output": "Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins (By similarity)."}]}
+{"id": "function_valid_4362", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAVCIIDHDNIRGVIYFEPVHGKDKVIGLKSGTYSLIIHRYGDISQGCDSIGSPEIFIGNIFVNRYGVAYVYLDTDVNISTIIGKALSISKNDQRLACGVIGISYINEKIIHFLTINENGV", "output": "Virion protein with no enzymatic activity."}]}
+{"id": "function_valid_4363", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNSLFMIFSLGIVGASLMVISTPNPVYSVFWLVIAFVNAAVMFISLGLDYIGLIFIIVYVGAIAILFLFVIMLIQQPNKIDSQDHSHFLPIGLSVIFLFYSLLTNSPKYISNPVIGSRTNIGAIGSHLYTTYYELVLIASLVLLVAMIGAILLAKQPNSPFLYNSHGESLRSRQDLFLQISREHL", "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)."}]}
+{"id": "function_valid_4364", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSSHYDVQALPAEQREHILRGFGLGWWRQLGQVAIVFGVVLLACWYVGLLDATTLLNGLPSIATLAGEAMPPDFSGYRSWIRPLIDTLAMSIAGTAIAVVFSLVVAFVAARNTAPHPLVFGVARVLLNALRSVPELIMGIIFVAAVGFGALPGVLALGLHSVGMVGKFFAEAIEHVDEAPVEAARAAGATPMQVLLHAVLPQVTPQFADVAIYRWEYNFRASTVMGMVGAGGIGFELMGSLRIMQYQEVAAILLVILAMVTLVDAFSGVLRKHFK", "output": "Probably forms part of a binding-protein-dependent phosphite transporter. Probably responsible for the translocation of the substrate across the membrane."}]}
+{"id": "function_valid_4365", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MARSVVVALLVLLSLSGLEAIQHAPKIQVYSRHPAENGKPNFLNCYVSGFHPSDIEVDLLKNGKKIEKVEHSDLSFSKDWSFYLLYYTEFTPNEKDEYACRVSHVTFSTPKTVKWDRTM", "output": "Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity)."}]}
+{"id": "function_valid_4366", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "EGDVAKGEAAFKRCSACHAIGEGAKNKVGPQLNGIIGRTAGGDPDYNYSNAMKKAGGEGLVWTPQELRDFLSAPKKKIPGNKMALAGISKPEELDNLIAYLIFSASSKPAZ", "output": "Cytochrome c2 is found mainly in purple, non-sulfur, photosynthetic bacteria where it functions as the electron donor to the oxidized bacteriochlorophyll in the photophosphorylation pathway. However, it may also have a role in the respiratory chain and is found in some non-photosynthetic bacteria."}]}
+{"id": "function_valid_4367", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "AYKIVTSQCTVCGACEFECPNAAISMKRGTYVIDATKCTECEGQFDKPQCVSVCPVDNTCVPA", "output": "Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions."}]}
+{"id": "function_valid_4368", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MRITEANPDPDAKAVPAAAAPSTASDAAAAAAATAATAAAAAAATAATAAAAAAATAATAAKAAALTAANAAAAAAATAAAAARG", "output": "Contributes to protect fish blood from freezing at subzero sea water temperatures. Lowers the blood freezing point. Binds to nascent ice crystals and prevents further growth (By similarity)."}]}
+{"id": "function_valid_4369", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSKSNESAVAFQTAIASIKLIQASSVLDLTEDDFDFLTRDRVWIATDRSRARRAIEACVYGTLDFVGYPRFPAPVEFISAVIAYYVHPVNIQTACLIMEGAEFTENIVNGVERPVKASELFAFTLLVRAGNKDLIGHAETNIREQLRAQGVM", "output": "Assembles the procapsid by joining twelve 12S pre-assembly complex into a T=1 icosahedral particle, called 108S procapsid. Ten proteins D bind each 12S complex, which are formed by three pentamers of F, G, B protein and a H protein. The scaffolding protein is released from the provirion after genome packaging to form the mature virion."}]}
+{"id": "function_valid_4370", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTLSRNSHKEDQLEEKVLVVNRCCKVVKGGRKFSFSALILVGDRKGRLGFGFAKANELTDAIRKGGDAARKNLVSINSLEGGSIPHEVLVNHDGAELLLKPAKPGTGIVAGSRIRLILEMAGVKDIVAKSLGSNNPMNQVKAAFKALLTLSCKDDIMKRRAVIND", "output": "With S4 and S12 plays an important role in translational accuracy.; "}]}
+{"id": "function_valid_4371", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSRTIFCTFLQREAEGQDFQLYPGELGKRIYNEISKEAWAQWQHKQTMLINEKKLNMMNAEHRKLLEQEMVNFLFEGKEVHIEGYTPEDKK", "output": "Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes."}]}
+{"id": "function_valid_4372", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "QGGWPRPGPEIPP", "output": "This peptide both inhibits the activity of the angiotensin-converting enzyme (ACE) and enhances the action of bradykinin by inhibiting the peptidases that inactivate it. It acts as an indirect hypotensive agent (By similarity)."}]}
+{"id": "function_valid_4373", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MARQMMTVGCLILIVVLLDMMVPVFNTCPGQYDECGNGPEEGECCGTHNYCCKNACTTYHHCHGGRDAGKLLRSLKKLKLTTH", "output": "Acts as a neurotoxin by inhibiting voltage-gated potassium channels (Kv)."}]}
+{"id": "function_valid_4374", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGIKNLKSLLLENKSLTILDDNLYKVYNGIFVDTMSIYIAVANCVRNLEELTTVFIKYVNGWVKKGGHVTLFIDRGSIKIKQNVRDKRRKYSKSTKDRKMLELEKCTSKIQNVTGFMEEEIKAEIQLKIDKLTFQIYLSDSDNIKISLNEILTHFNNNENVTLFYCDERDAEFVMCLEAKTYFFTTGEWPLIISTDQDTMLFASVDNHPKMIKNLTQLFKFVPSAEDNYLAKLTALVNGCDFFPGLYGASITPTNLNKIQLFSDFTINNIVTSLAIKNYYRKTNSTVDVRNIVTFINDYANLDDVYSYIPPCQCTVQEFIFSALDEKWNDFKSSYLETVPLPCQLMYALEPRKEIDVSEVKTLSSYIDFENTKSDIDVIKSISSIFGYSNENCNTIVFGIYKDNLLLSINSSFYFNNSLLITNTKSDNIINIGY", "output": "Putative nuclease that seems to be required for double-strand break repair, homologous recombination, and production of full-length viral genomic DNA."}]}
+{"id": "function_valid_4375", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTNLLNKSLEENGSFLTAVYIFVGFVALYLLGRALQAFVQAADACCLFWYTWVVVPGAKGTAFVYNHTYGKKLNKPELEAVVVNEFPKNGWNNKNPANFQDVQRNKLYS", "output": "Plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis."}]}
+{"id": "function_valid_4376", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSAMTRVSEVIIGIVSAGVVSALVFPRYTGEQMRTTVRKRFGSFVDYVASALSGQLDRAHIETIHTRFAYVVGFEAARSMAVFEDPDTRMRSGRLARLNSEFMSASSRFHALHQLMNRLHAAGAQAAIDAIEPYFREIAPLLTRNGEPVRTSIDAAHSAEQLLAWRDALPRRIRATRAELETQPDFPLLDFDTAAELLYRFITDLQEYAATYASLATATHERERWIERYEPRTNKTAATIAGIRTATVILALGWFWIETAWPSGVMLVLNAAATCALASSAPRPTAMAAQMGMGTALAVCTGFLLTFGIYPRIDGFVLLCAALAPLLAIGIYMSLKPKLAGYGGAI", "output": "Involved in the resistance (detoxification) of the fungal toxin fusaric acid."}]}
+{"id": "function_valid_4377", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "IYVRPTKDELLYCGEFRELGQPDKKCRCDGKPCTVGRCKFARGDADDKCTSA", "output": "Potent inhibitor of fibrinogen interaction with platelet receptors expressed on glycoprotein IIb-IIIa complex. May prevent blood from clotting during either feeding and/or storage of ingested blood."}]}
+{"id": "function_valid_4378", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MPLTPPPDYTRVYTALAIGASIAFFTGLITRNTLPSVGDLQHNLPHGGRYRDGTKSVEYCGPRKLNSVESGSRWTFQPWLLVIVLVALIIALGRQGHNCRACGRSH", "output": "Plays a role in viral cell-to-cell propagation, by facilitating genome transport to neighboring plant cells through plasmosdesmata,."}]}
+{"id": "function_valid_4379", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEKVKAWLIKYKWWIVAAIGGLAAFLLLKNRGGGSGGGGEYMVGSGPVYQQAGSGAVDNTMALAALQANTQLSAQNAQLQAQMDASRLQLETQLNIETLAADNAHYSTQSQLQLGMAQVDLSKYLGDLQSTTSTALAGMQSDTAKYQSNIQLQAENIRANTSLAEIDAQKYIVGKQADIAKYQAKTERRGQDYGFALGLLNFGGKFF", "output": "Component of the phage ejection machinery. Pilot protein for the formation of the tube that conducts the genome into the target cell. Probably involved in penetration of the bacterial outer membrane and for making the peptidoglycan layer accessible to the viral transglycosylase. Essential for viral infectivity."}]}
+{"id": "function_valid_4380", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MATMIRGHRLRIAEGDIPIAGVKSSRIYSDISPFKKASDLMIHWNEFVFKVMPEDIAGDGFRLASIPVIPSSEVQAVLRKRESTNYVHWGALSISIDALFRKNAGVSGWCYVYDNRWETFEQAMLQKFHFNLDSGSATLVTSPNFPVSLDDPGLSNSISVAVMFENLNFKFESYPISVRVGNMCRFFDSFLSSVKNKVDSNFLLEASNADPLGVGAFGFEQDDQVSELFNYIQTVPTQAIKFREHEIPKGFLGMMGKKKIKSFEFASGSKGMERRKPNRGKQIDRSFSQRAVPGFRSQNEKVEHQGLSTDSDFENFLRNKRGNKAGVKSTASEGSSVDNISSREFQFARQNQAKEDGSSSEFAAQGGRKSKGISGRRKQTSSWKDRGNPGTDTGVHLREHSDPGNVRADGVSGPSGGSEINGGSISPRVLQPEGSGQLDQSFQDYLFGPEHQQNDIPSGL", "output": "Suppressor of viral-induced RNA silencing."}]}
+{"id": "function_valid_4381", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTEQKRPVLTLKRKTEGETPTRSRKTIINVTTPPKWKVKKQKLAEKAAREAELTAKKAQARQALSIYLNLPTLDEAVNTLKPWWPGLFDGDTPRLLACGIRDVLLEDVAQRNIPLSHKKLRRALKAITRSESYLCAMKAGACRYDTEGYVTEHISQEEEVYAAERLDKIRRQNRIKAELQAVLDEQ", "output": "One of the components on the FinOP fertility inhibition complex, which inhibits the expression of traJ gene, which in turn regulates the expression of some 20 transfer genes. The transfer genes are responsible for the process, called conjugal transfer, in which DNA is transmitted from one bacterial host to another. RNA-binding that interacts with the traJ mRNA and its antisense RNA, finP, stabilizing finP against endonucleolytic degradation and facilitating sense-antisense RNA recognition (By similarity)."}]}
+{"id": "function_valid_4382", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "AVDDYAATRYPIILVHGLTTDSKYGGVVEYXYRNPNDLTSHXXAAYVYELRSDPLD", "output": "This thermostable and solvent-tolerant lipase is rather nonspecific. It can synthesize both primary and secondary alcohol esters. Simple triglycerides of short and middle chain fatty acids (C<13) are the preferred substrates."}]}
+{"id": "function_valid_4383", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSQNILLLIRADIKAVDEKVDALQQAVNDVSANLPDTSELSAKLDAQATTLDTIVTQVNNINDVLNPDLPDVPGNLQKQQQQKKSNKK", "output": "Seems to be involved in the morphogenesis of the polyhedra. Forms extensive fibrillar structures in both nucleus and cytoplasm. It is involved in the liberation of polyhedra from infected-insect cell."}]}
+{"id": "function_valid_4384", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKKNFPFHMVTNSPWPIILSFSFMNTLISTVIWIYSSISMFMILNFINSILIMMLWFRDIIRESTFQGMHSMFITNFLKFSMILFILSELMFFISFFWTFFHSSISPNIEINMTWPPKNIKFFNPMEIPLLNSFILVSSGFTVTLSHYYLIINNLKLSKSYLLLTILLGIYFTILQTIEYSNSFFCFNDSIYGSIFFMATGFHGLHVLIGSIFLLISLYRMMNIHFSNMHNMNFELAIWYWHFVDVIWLFLYTFIYLLI", "output": "Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix."}]}
+{"id": "function_valid_4385", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAKKDGNQEEEISQMEEGNIHSASNSDSNVGFCSSVSVVVILQKLIAEAIGTYFVIFAGCGSVAVNKIYGSVTFPGICVTWGLIVMVMVYTVGYISGAHFNPAVTITFSIFGRFPWKQVPLYIIAQLMGSILASGTLALLFDVTPQAYFGTVPVGSNGQSLAIEIIISFLLMFVISGVATDDRAIGQVAGIAVGMTITLNVFVAGPISGASMNPARSIGPAIVKHVYTGLWVYVVGPIIGTLAGAFVYNLIRSTDKPLRELAKSASSLRS", "output": "Aquaporins facilitate the transport of water and small neutral solutes across cell membranes."}]}
+{"id": "function_valid_4386", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MALIFICILHCGIWANAVNAFHIFLQITMWRLNDNKVYLPPPGPIASIVSTDEYVQRTNLFYYAGSSRLLAVGHPYFPLKNSSGKITVPKVSGYQYRVFRVKLPDPNKFGFSETTLVTSDTQRLVWGCVGVEIGRGQPLGVGISGHPYLNKYDDTENPSGYGTSPGQDNRENVAMDYKQTQLCIVGCTPPMGEYWGQGVPCNASGVTQGDCPVIELKSEVIQDGDMVDTGFGAMDFASLQASKSDVPLDLVNTKSKYPDYLGMAAEPYGNSLFFFLRREQMFLRHFFNKAGKTGDVVPSDMYIAGSNTRSKIADSIYFSTPSGSLVTSDSQLFNKPLWIQKAQGHNNGICFGNQLFVTVVDTTRSTNLTLCASTDPTVPSTYDNAKFKEYLRHVEEYDLQFIFQLCIITLNPEVMTYIHTMDPTLLEDWNFGVSPPASASLEDTYRFLSNKAIACQKNAPPKEREDPYKKYTFWDINLTEKFSAQLTQFPLGRKFVMQAGLRPKPKLKTVKRSAPSSSTSAPASKRKKTKR", "output": "Forms an icosahedral capsid with a T=7 symmetry and a 50 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. Binds to heparan sulfate proteoglycans on cell surface of basal layer keratinocytes to provide initial virion attachment. This binding mediates a conformational change in the virus capsid that facilitates efficient infection. The virion enters the host cell via endocytosis. During virus trafficking, L1 protein dissociates from the viral DNA and the genomic DNA is released to the host nucleus. The virion assembly takes place within the cell nucleus. Encapsulates the genomic DNA together with protein L2."}]}
+{"id": "function_valid_4387", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "DICDIAIAQCSLTLCQDCENTPICELAVKGSCPPPWS", "output": "Mating ciliate pheromones (or gamones) are diffusible extracellular communication signals that distinguish different intraspecific classes of cells commonly referred to as 'mating types'. They prepare the latter for conjugation by changing their cell surface properties."}]}
+{"id": "function_valid_4388", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSDFNLVGVIRVMPTDPDVNLDELEEKLKKVIPEKYGLAKVEREPIAFGLVALKFYVLGRDEEGYSFDEVAEKFEEVENVESAEVETVSRI", "output": "Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA."}]}
+{"id": "function_valid_4389", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MITIYTAPSCTSCKKAKTWLSYHHIPFNERNLIADPLSTTEISQILQKCDDGVEGLISSRNRFVKTLGVDFEDISLSQAIKIISENPQIMRRPIIMDEKRLHVGYNEEEIRAFLPRTVRVLENGGARLRSAI", "output": "Global transcriptional regulator that plays a key role in stress response and exerts either positive or negative regulation of genes. Acts by interacting with the C-terminal domain of the alpha subunit of the RNA polymerase (RNAP). This interaction can enhance binding of RNAP to the promoter region of target genes and stimulate their transcription, or block interaction of RNAP with activator."}]}
+{"id": "function_valid_4390", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAETSNNKTSEEAKANEKKSQSETLEESKLENMNSEESTETTQTESMETAETETSLQTELESAKKEIESLKDSWARERAEFQNFKRRSAQEFVSIRKEAVKSLVSGFLNPIDNLERVGATQTNSEELKPFVDGVTMILKEFYSVLEKSNVIRFDPKGEPFDPMSMEALSSEEGDQYSEETVIDVYQPGYYYKENEDKFTLRPARVRIGKPKS", "output": "Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding."}]}
+{"id": "function_valid_4391", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MHCPFCRHPDSRVIDSRETDEGQAIRRRRSCPECGRRFTTVETAVLAVVKRSGVTEPFSREKVISGVRRACQGRQVDDDALNLLAQQVEDSVRAAGSPEIPSHDVGLAILGPLRELDEVAYLRFASVYRSFSSADDFAREIEALRAHRNLSAHS", "output": "Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes."}]}
+{"id": "function_valid_4392", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGLFGMMKFAQTHHLVKRRGLRAPEGYFTPIAVDLWNVMYTLVVKYQRRYPSYDREAITLHCLCSMLRVFTQKSLFPIFVTDRGVECTEPVVFGAKAILARTTAQCRTDEEASDVDASPPPSPITDSRPSFAFSNMRRRGHAFAPGDRGTRAAGPGPAAPSGAPSKPALRLAHLFCIRVLRALGYAYINSGQLEADDACANLYHTNTVAYVHTTDTDLLLMGCDIVLDISTGYIPTIHCRDLLQYFKMSYPQFLALFVRCHTDLHPNNTYASVEDVLRECHWTAPSRSQARRAARRERANSRSLESMPTLTAAPVGLETRISWTEILAQQIAGEDDYEEDPPLQPPDVAGGPRDGARSSSSEILTPPELVQVPNAQRVAEHRGYVAGRRRHVIHDAPEALDWLPDPMTIAELVEHRYVKYVISLISPKERGPWTLLKRLPIYQDLRDEDLARSIVTRHITAPDIADRFLAQLWAHAPPPAFYKDVLAKFWDE", "output": "Minor structural protein that acts as an endoribonuclease during lytic infection. Degrades host mRNAs in the cytoplasm by cutting them at preferred sites, including some in regions of translation initiation. Together with inhibition of host splicing by ICP27, contributes to an overall decrease in host protein synthesis. Also, after the onset of viral transcription, accelerates the turnover of viral mRNA, thereby facilitating the sequential expression of different classes of viral genes. Binds translation initiation factors eIF4H, eIF4AI, and eIF4AII, thereby may interact directly with the translation initiation complex and thus digest specifically mRNAs. Also impedes antigen presentation by major histocompatibility complex class I and class II molecules, inhibits secretion of cytokines that would otherwise recruit lymphocytes and neutrophils cells to the site of infection and blocks the activation of dendritic cells. Impedes the alpha/beta interferon-mediated response to infection (By similarity)."}]}
+{"id": "function_valid_4393", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "FMRF", "output": "Myoactive; cardioexcitatory substance. Pharmacological activities include augmentation, induction, and regularization of cardiac contraction."}]}
+{"id": "function_valid_4394", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWAAVMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLLWFSCLLSGLGGTLFDPPRSALVVKLIRPQQRGRFFSLLMMQDSAGAVIGALLGSWLLQYDFRLVCATGAVLFVLCAAFNAWLLPAWKLSTVRTPVREGMTRVMRDKRFVTYVLTLAGYYMLAVQVMLMLPIMVNDVAGAPSAVKWMYAIEACLSLTLLYPIARWSEKHFRLEHRLMAGLLIMSLSMMPVGMVSGLQQLFTLICLFYIGSIIAEPARETLSASLADARARGSYMGFSRLGLAIGGAIGYIGGGWLFDLGKSAHQPELPWMMLGIIGIFTFLALGWQFSQKRAARRLLERDA", "output": "Confers resistance to norfloxacin and enoxacin."}]}
+{"id": "function_valid_4395", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "RFKKIRRLGALPGFTSKRPRSGSDLKNQLRSGKKSQYRIRLEEKQKLRFHYGLTERQLLKYVHIAGKAKGSTGQILLQLLEMRLDNILFRLGMASTIPGARQLVNHRHILVNDRIVDIPSYRCKPRDIITTKNKQRSKALIQNYIASSPHHEELPNHLTIDPFQYKGLVNQIIDNKWIGLKIN", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; "}]}
+{"id": "function_valid_4396", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "GVPSVSTVNVAQKQHDVNFLLFKVYI", "output": "Hemocyanins are copper-containing oxygen carriers occurring freely dissolved in the hemolymph of many mollusks and arthropods."}]}
+{"id": "function_valid_4397", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "GLLQTITEKLKEFAGGLVTGVQS", "output": "Has no antimicrobial or anticancer activity."}]}
+{"id": "function_valid_4398", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "APPGFTPFRSKAV", "output": "Produces in vitro relaxation of rat arterial smooth muscle and constriction of intestinal smooth muscle (By similarity). May target bradykinin receptors (BDKRB)."}]}
+{"id": "function_valid_4399", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNKKVIAIVVGVVVVLVAILGVVAWFVPILKVGNIEVTGATRTDPDQVLEVSGIVEGENLFRVDATAAGQNIVELPWVKSVTVNRALPSTITVELTEREPAVFIKRADGDHVIDTEGKEIIIGTPPVGTVEVSGADEGNSEVLPAVIAVINAIKAQDAQMTESIQVVEAPDQFDILLKMNDGREIYWGSSENNHDKAVAMSTVLKREGQRWNISSPSMVTVR", "output": "Essential cell division protein."}]}
+{"id": "function_valid_4400", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTTRYLLDKSAAYRAHLPAVRHRLEPLMERGLLARCGITDLEFGVSARSREDHRTLGTYRRDALEYVNTPDTVWVRAWEIQEALTDKGFHRSVKIPDLIIAAVAEHHGIPVMHYDQDFERIAAITRQPVEWVVAPGTA", "output": "Toxic component of a type II toxin-antitoxin (TA) system. An RNase. Its toxic effect is neutralized by coexpression with cognate antitoxin VapB21 (By similarity)."}]}
+{"id": "function_valid_4401", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGVMGGTFDPIHYGHLVAASEVADLFDLDEVVFVPSGQPWQKGRQVSAAEHRYLMTVIATASNPRFSVSRVDIDRGGPTYTKDTLADLHALHPDSELYFTTGADALASIMSWQGWEELFELARFVGVSRPGYELRNEHITSLLGQLAKDALTLVEIPALAISSTDCRQRAEQSRPLWYLMPDGVVQYVSKCRLYCGACDAGARSTTSLAAGNGL", "output": "Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)."}]}
+{"id": "function_valid_4402", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MPDLKSLIREVPDFPKPGILFYDITTLLKDPSGFHGVIDGLKDHYRDIKVDTVLGIEARGFIFAPALAYALGAGFVPVRKPKKLPAECVRITYDLEYGTDTLEMHKDAIGNGHRVLIVDDLLATGGTASAAARMVQDAGGIVVGLGFVIELTFLAGRQRLNGHDVFSLLQYDK", "output": "Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis."}]}
+{"id": "function_valid_4403", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAKITRKRRVKKNIESGIVHIQSTFNNTIVMITDVHGNALAWSSAGALGFKGSKKSTPFAAQMASEAAAKAAQEQGLKTVSVTVKGPGSGRESAIRALAAAGLNVTSISDVTPVPHNGARPPKRRRV", "output": "Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome."}]}
+{"id": "function_valid_4404", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MQTVGMIAEFNPFHTGHAYALAQARKLAQADVVVVVMSGNYVQRGEPAIFDKWIRAQAALQHGADIVVELPVTGAVQAADQFAEAGVTALAAMGVNTLAFGTEHPEVAYADLAEKLATAALTGDGFRDYTQTYATQLNAVYAKAAGITQTDPNFMLGLSYAKANLALKRPMTLLPFARRGIGHDEVGIQANIASASTVREYLRADQSVEAIVPTELVDFYAKQQQYSWAQFFPWLKYRLQTAELNELRLVATMAEGLEYRFTQKIDDAQDMTAFLKQVKSKRYTYARLRRLALAITLNMTATAVNQARQHPQLHVLGFTPTGRQYLNSVKHDLDWPLLTKVSADMLAPDGVLAMTHRADRLITTIGGVEQNYGRRPLM", "output": "Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34."}]}
+{"id": "function_valid_4405", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAATNQPMIQLKDVSKIYDNGTVGLKDINLNIDKGEFVVVVGLSGAGKSTLLRSINRLQDVSKGDILIDGKSITSAKGKDLREIRRDIGMIFQSFNLVKRSSVLRNVLTGRVAYYPTWKTTFNLFTKEDKQKAYEALQRVDLADKVYTRADQLSGGQQQRVAIARVLTQNPKIILADEPTASLDPQTSRRVMHDLKMLNEEYGMTVVANLHSVELAKEFGDRVIGVRAGQIVYDGKMSETSQAVFDDIYNGGNGKKGEEDA", "output": "Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system."}]}
+{"id": "function_valid_4406", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNVLPCSINTLKGLYDLSGVEVGQHFYWQIGGFQVHAQVLITSWVVIAILLGSATIAVRNPQTIPTKSQNFFEYVLEFIRDLSKTQIGEDYGPWVPFIGTMFLFIFVSNWSGALLPRKIVQLPHGELAAPTNDINTTVALALPTSVAYFYAGLTKKGLGYFGKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADELVVVVLVSLVPLVVPIPVMFLGLFTSGIQALIFATLAAAYIGESMEGHH", "output": "Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane."}]}
+{"id": "function_valid_4407", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MCSPSETKTSVIDQLKRAASAEEFFTTLGVDYDPQVVNVARLHILKRMGQYLASEDLAGLSNCAVTERCKAVLERAYADFVASSPLDQRVFKVLKDAVSPKRGAFVPLDALK", "output": "May protect the nitrogenase Fe-Mo protein from oxidative damage."}]}
+{"id": "function_valid_4408", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRCPSCSSLDTQVKDSRPTEDSSVIRRRRVCLACNFRFTTFERVQLRELTVIKRNGRRVPFDRDKLVRSLQISLRKRPVDPERLEEMVSAVVRELESGGESEISSEAIGEIVMEHLRKLDDVAYVRFASVYRNFREAKDFEAVLGELSSDELARAALLRK", "output": "Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes."}]}
+{"id": "function_valid_4409", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSYTINAVTRTEIGKGSSRRLRHAGKVPAVIYGPGKEPVSIKFEHKDIINIQLNDDFYTTDLTVSIEGKEVKVRVKAIQRHAFKQLVEHIDFMFA", "output": "This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance."}]}
+{"id": "function_valid_4410", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAPTPELSPETLARHLAVLGPASGYCVAYSGGLDSTVLLHLMAALSAARELPLRAVHIHHGLQPQADAWAEHCRQQAAALGVDCLVLPVEVRRDSGEGLEAAARQARYAALASHLQSGEALLTAHHADDQAETVLLHLLRGSGPRGLAGMRAQRPLGRGRLLRPLLPWPRERLRAYGDTHALCWVEDPSNAHVAHDRNWLRHTLWPVLTQRWPDASRRVGRAAGEQAEAEALLRELAGEDLARHPPGPGLAVSVLARLSPARARNLVRHWLLMSGLRPPPRARLEQGLADLIRAGRDRQPVLTWPEGELRRYRDRIHRLPAGGPPPWPGPDREWDLRVPLVVPGVGVLRLVRADEGIAPSLIGAEGLSVGRRRRGERCQLAHDPGHRPLSKRFQEAGIPPWERDRVPILRRGEEVVAIANLGTAKRFTARPGYRLICEEHGPDGG", "output": "Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine."}]}
+{"id": "function_valid_4411", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIQMQSLLKVADNTGARTVMCIKVLGGSKRRFAGIGDVIKVAVKDAAPRGRIKKGEVYNAVIVRTAKGIRRSDGSLVKFDTNAAVILNNKLEPIGTRIFGPVTRELRTAKFMKIVSLAPEVI", "output": "Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome."}]}
+{"id": "function_valid_4412", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSVSRMIPRLVRASASPMAVPTAFRRSFGSSVVCAKDNDGPRGPSTPSTAPEYRQNQTSKPPNQFMPNSTSTMTNDYPKVGEKASPPELLNSVDPNYRPADPYSGKVQHFTGGRQEPGAQKPELGLGEMEGITFKVEPLQRSGEDTTTMRARLLYQSRKRGILESDLLLSTFADVYLAKMNHEQLQEYDRFLDENDWDIYYWATQDAPEEGTPAEDTPTETWQRTGAKSGEWRQTIGAFKAAYRPVPTRWADSEVLRLLREHVRDNSATGFHAAKNKKTGGSGLGRMPNIQVFDS", "output": "Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer."}]}
+{"id": "function_valid_4413", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAIVGLGTDIVEIERITAHVARSGDKLAKRVLTEAEFDIYQQHSQPSRYLAKRFAAKEAAAKALGTGIGRGVSFQHIHIGNTPDGAPTIDFTQGAQQRLALLNGVVGHISIADEKSYAIATVILESR", "output": "Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein."}]}
+{"id": "function_valid_4414", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEIIIISGRSGAGKSVALRALEDIGYYCVDNLTMDLVPQLVDMLENKQHLVAISLDIRNLPQEPETLDHILNLLQEKYPVKIIFLDTDRNTLIRRYSDSRRLHPLSVQNLSLEAAIAAEKEHLEPLVQHANVIIDTTPLSPHELAERLREFLRGNTEKELQIIVESFGFKYGIPLDADYVFDVRFLPNPHWNQELRPMTGLEKPVIEFMQKHIEVDNFIYQTRNYIENWLPMLEKNNRSYLTIAIGCTGGKHRSVYIAQQIGEYFRAKGKKVQIQHKSLEKHTQNK", "output": "Displays ATPase and GTPase activities."}]}
+{"id": "function_valid_4415", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MNTNKQFKVYTTSAVDFAQDPTALSSNINAPQFDKAIVVHVFFSQNKNLEDLQEFQLLVKSANVDILSIITTSRSTPQAKYFVGQGKAEEIAQAVEQLNADIVLVNHSLTPAQARNLESICQCRVVDRTGLILDIFAQRARSHEGKLQVELAQLRHLATRLVRRKTGLDQQKGAVGLRGPGETQLETDRRLIKVRITQLQNRLEKVAKQRNQNRQTRRKADIPTISLVGYTNAGKSTLFNVLTQANVYVADQLFATLDPTLKRLPIQDVGNCVLADTVGFIRELPHDLVSAFKSTLQETTEASLLLHVIDVADSRKLENMLTVNEVLSEIKANQVTTLLVYNKIDQVENIQPHIEFDEENQPIAVYLSAQLNQGLDLLVEAIRQKLSHEILHLEINLAAQYGKIRHCFYQLNCVRQEKINEQGEFLLDIQIDKIEWLKLSKQFPLLKRFYETTEISDK", "output": "GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis."}]}
+{"id": "function_valid_4416", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSQYTIPHVIERTPAGERSFDIFSRLLNERIVFLGTEIDDGVANVVMAQLLHLQADSSDQEIGLYINSPGGSTTAMLAIYDTMQFLRPTIATYCMGQAASAAAVLLAAGTKGHRHVLAHSRTLLHQPSTQGNGTISDLALQAAEIMRVRSQTEAILSKHTGQTVERLRRDTDRDRIFTAEEAIEYGLADTLVAA", "output": "Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins."}]}
+{"id": "function_valid_4417", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MATNNTQNLRKSFAKTRSTVEYPDFLDIQVRSFKDFFQIDTPAENRFKEGLYKVFAENFPISDSRDNFILDFIDYNIDTPKYNVDECIDRGLTYAVPLKAKLRLTCNDKDNEDFQTIEQEVFLGNIPYMTERGSFVINGAERVIVSQLHRSPGVFFAQSKHTNGTKLYSARVIPFKGSWIEFATDVNNVMFAYIDRKKKFPVTTLLRAIGYGSDKDILDLFGLSEEVEATKANIKKAIGRKLAARVLRTWTEDFVDEDTGEVVSIDRNEVLLERDSIIKEEDINIIVESGSKSIILHREDVNIADYTIIYNTLQKDNSNSEKEAVEQIYRQLRNTDAPDEQTARDIIHNLFFSDKRYDLGEVGRYRINKKLGSGMGSEVKVLTKEDIINIVKYLIGLINSRAVVDDIDHLSNRRVRTMGEQLYSQFSVGLARMARTIKERMNVRDNEDFKPVDLINARTLSSVINSFFGTNQLSQFMDQTNPLAEITHKRRMSALGPGGLSRERAGFEVRDVHYTHYGRLCTIETPEGPNIGLISSLCVHAKVNSMGFIETPYRKVIDGIVDVKNQPVFLTAEEEDGAHIAQANAMYDDNGNFISDRIKARYEGDFPVIAPDKVDLIDIATNQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPLLRPEAPIVGTGLERRVAMDSRTLLIAEADGVVEFVDANEIKMRYDLTDEDRLVSFDSDIITYSLIKFRRTNQDTCINLKPVIQHGERVKKGQVLCEGYATDKGELALGRNLMVAFMPWQGYNFEDAIVISEKVVRDDIFTSIHIEEFELEVRDTKRGEEELTSEIPNVSEEAVKNLDENGIIRTGAEIKEGDILIGKITPKGESDPTPEEKLLRAIFGDKAGDVKDASMKAPPSLRGVVIDTKLFSRPKKDKDLRIKSKKQVETIKGKYSKDLLALREQMIEKLAALLDGQTSQGVKHKFGDEVISKGVKFSRKNIEANVFPDKNPYRDESNYNVQEEANLLGDLIIDNWTSDKKINENVLRLVKNYLTKRNETAGKFKRERFTLEVGDELPAGIVQLAKVYIAKKRKLKVGDKMAGRHGNKGVVARIVRDEDMPFLEDGTPVDIVLNPLGVPSRMNIGQIYETLLGLAGKKLGRKYATPIFDGASEEEVINELRDAGLPTIGRTKLVDGLSGNPFDQPVTVGVIYMMKLGHLVDDKMHARSIGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAFGAANILQEILTVKSDDVVGRAKTYECIVKGENLPRPNIPESFNVLVHELRGLALEITLH", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_valid_4418", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIINAKGPASFAEKYIVRSIWDNKFPPGSILPAERELSELIGVTRTTLREVLQRLARDGWLKIQHGKPTQVNNFWETSGLNILETIADLNPEGFPVLVDQLLSARTNVSAIYFRGALRNNPDQAVDVLAGIHQLENTAEAFAEFDYQLHHRLAFSSGNPLYVLILNGFKGLYSRVGRYYFSSSDARALALNFYVELEKLALAKNYIDVPAVMRSYGINSGKMWQRLRDDMPADIAQDKS", "output": "Multifunctional regulator of fatty acid metabolism."}]}
+{"id": "function_valid_4419", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MKTVQDYIRTIVDFPHEGIMFRDVTTLFADPRGFRIAIDQMLHPYAGLQIDKVVGLEARGFILGGAIAHQLSKGFVPIRKKGKLPGKTISEAYTLEYGEAIVEIHDDAIQPGEKVLVVDDLLATGGTAEAGIKLIERLGGEIISTSFIIDLPDLGGRARLEAMGVEVNALCAYEGL", "output": "Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis."}]}
+{"id": "function_valid_4420", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAAAQHRPVMLEEAVRALAPSGGDVVVDATFGGGGHSARVLRELGPGGRVVGIDRDPEARGRAERLLGDPRFSFEQGPYDEVLWRMVGRGERADALLFDLGLSSFQVDDPRRGFSYTREGPLDMRMDPGSGPSAADFLNAAGEAEIAGVLSEYGDVPRAQARRVAREILRRRPLRTTADLREAVRAAVGWAPRGGNPAKRVFQAVRIRVNDELGGLRRALEAAERLLVPGGRLVVISFHSGEDRLVKRFIAEREGRCTCPPELPVCVCGARPVFRRGPVLRPSEREVAENPRSAPARMRVAFRTAEPAREAS", "output": "Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA."}]}
+{"id": "function_valid_4421", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MIQSQHSQTARHALAETVVLAKARKNLSFAQLTEGTGLSEAFVTAALLGQHALPADAARVVADKLGLDDDAVLLLQMIPLRGSIDDRVPTDPTIYRFYEMLQVYGTTLKALVHEKFGDGIISAINFRLDVKKVDDPEGGSRAVITLDGKYLPTKPF", "output": "Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide."}]}
+{"id": "function_valid_4422", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSAALRFDNIGKVFPGVRALDGISFDVHAGEVHGLMGENGAGKSTLLKILGGEYQPDAGSVLVDGRPVQFANAAASIAAGIAVIHQELQYVPDLTVAENLLLGRLPNAFGWVKKREAKRYVRERLAEMGVDLDPDARLGRLSIAQRQMVEICKALMRNARVIALDEPTSSLSHRETEVLFKLVDDLRAQGRALIYISHRMDEIYRLCDACTIFRDGRKIASHDALADVPRERLVAEMVGREIADIYHYAPRTLGDVRFSAEGVDGPALREPASFSVRAGEIVGFFGLVGAGRSELMRLVYGADRRRAGALTLDGKRIDVKRTGDAIRHGIVLCPEDRKEEGIIAIASVAENINISCRRHSLRAGLFINGKTESETADRFIQRLKIKTPNRRQKIRFLSGGNQQKAILSRWLAEPDLKVVILDEPTRGIDVGAKHEIYDVIYRLAERGCAIVMVSSELPEVLGVSDRIVVMREGRIAGELPRADANEHAVLNLALPQTSAVEAA", "output": "Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system."}]}
+{"id": "function_valid_4423", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MQNQRIRIRLKAFDHRLIDQSTAEIVETAKRTGAQVRGPIPLPTRKERFTVLISPHVNKDARDQYEIRTHKRLVDIVEPTEKTVDALMRLDLAAGVDVQISLG", "output": "Involved in the binding of tRNA to the ribosomes."}]}
+{"id": "function_valid_4424", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MANLRDIRKKIGSVKNTQKITHAMKLVSTSKLRKAEEVARNSRAYALKLDAVFDDVLSKMKNQGIEDIQSKYFRELERLEIKKVDIIFITADKGLCGGFNTNTIKKVLACTNEYKEKDIKVRLCGIGKKGNEYFSFNGIEVLDKINNLSSMPNYERAQEFMKKVVEDYLSGKTDKVIIIHNGFKNMISQEIRVKTILPIGYKIIHQNPQPNEAQETITSEPSGSEDEILDSLAEKYVEYSLYYALIDSLAAEHSARMQAMDTATNNAKDLVKTLTISYNKARQEAITTELVEINAGVEALK", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex."}]}
+{"id": "function_valid_4425", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MARRRRGTPIDGVLLLDKAPGVSSNRALQQVRRLYDAQKAGHTGTLDPMATGLLPVCFGEATKFSAYLLDADKTYRTWVRLGEVTDTGDAEGTVIEHHSVPALDERDIEAALAGFRGEVEQVPPMYSALKHQGRPLYELAREGKHVERAARRVTVYDMRLLSCEAEGFELEVRCSKGTYIRTLAEDIGHALGCGAHITSLRRLRSGPFEADAMHAFSALEDLDAASREARLLPVDTMLTHLPSLEVAASASRRLLHGQRAQIDTAGLAAQSTARLYRDAAFLGLVTVTECGEVAPRRLLNTASLASE", "output": "Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs."}]}
+{"id": "function_valid_4426", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MALTQEDIINAVAEMSVMEVAELISAMEEKFGVSAAAAVVAGPGAGGEGEAAEEQTEFDLVLTGAGDKKVNVIKVVREITGLGLKEAKGAVDGVPATLKEGMSKEDAEAAKTKLEEAGASVELK", "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation."}]}
+{"id": "function_valid_4427", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSKPVVAIVGRPNVGKSTLFNRLAGGLVAIVENRPGVTRDRLYRDSEWLGRKFTIIDTGGIEFVNENTPITAQMRRQAEIAIEEADVIVFVIDAQISPTPDDDMIAQTLRRSGKPVILAANKVENFAKTELYEFYNLGLGEPVPISAVHGMNIGDLLDEVVSHFPEDIEEEVDPDTIRIAVVGRPNVGKSSLVNTLLGEERVIVSNIPGTTRDAIDSAFEHEGKHYIIIDTAGMRRKGRIEELTEQYSVSRSLRAVDRSDVILMLLDAGEGVTEQDKKIAGYAHEAGKGIVLVVNKWDLIEKDDKTMNRFEKDIREELGFMQYAPTLFISAKTGQRVTKLLDLVDFVAEQNSTRVATATLNTLVREWVHLNPPPTDKGRRLKVLYATQVGVKPPTFVFFVNDHELMHFSYRRYLENQLRSSFGFEGSPIRMIVRQKDEERE", "output": "GTPase that plays an essential role in the late steps of ribosome biogenesis."}]}
+{"id": "function_valid_4428", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGFKFLEVIKPFCIILPEIEKPQRKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSESADPFYWMRVIMASNRGTLMELGITPIVTSGLIMQLLAGAKLIEVGDTPKDRALFNGAQKLFGMIITIGQAVVYVMTGMYGDPSDMGAGICLLIIIQLFIASLIVLLLDELLQKGYGLGSGISLFIATNICETIVWKSFSPATVNTGRGTEFEGAVIALFHLLATRSDKVRALREAFYRPNLPNLMNLSATILVFGIVIYFQGFRVDLPIKSARYRGQYSSYPIKLFYTSNIPIILQSALVSGLYVISQMLAIRFRGNFFIGLLGVWEDVEGGGPARSYPVALCYYLSPPESFFSMFLDPIHGLLYITFMLGSCAFFSKTWIEVSGSAAKDVAKQLKEQQMVMRGHREKSMIHELNRYIPTAAAFGGLCIGALSVLADFIGAIGSGTGILLAVTIIYQYFEIFVKEQAEVGGMGTLLF", "output": "Component of SEC61 channel-forming translocon complex that mediates transport of signal peptide-containing precursor polypeptides across the endoplasmic reticulum (ER). Forms a ribosome receptor and a gated pore in the ER membrane, both functions required for cotranslational translocation of nascent polypeptides. May cooperate with auxiliary protein SEC62, SEC63 and HSPA5/BiP to enable post-translational transport of small presecretory proteins. The SEC61 channel is also involved in ER membrane insertion of transmembrane proteins: it mediates membrane insertion of the first few transmembrane segments of proteins, while insertion of subsequent transmembrane regions of multi-pass membrane proteins is mediated by the multi-pass translocon (MPT) complex."}]}
+{"id": "function_valid_4429", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKEEKKLLLQEVEEKISASQGFILLRYLGFTAAHSREFRNSLSGVSAEFEVLKKRIFFKAIQSAGFDIDSSDTSGHLGVVFAYDDAVSAAKQVLDFNKQHNDSLVFLAGRIDSANLSGKEVEAVAKLPSMKELRQQIVGLIAAPMSQVVGIMGSALSGVVSCIDQKIQKN", "output": "Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors."}]}
+{"id": "function_valid_4430", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MEDKNILYGPEPFHPLADGTAGEQMFYALSRYADISGCIALTNAHTKENVLYEEFLKLSCRLAESFKKYGLKQNDTIAVCSENGLQFFLPLIASLYLGIIAAPVSDKYIERELIHSLGIVKPRIIFCSKNTFQKVLNVKSKLKYVETIIILDLNEDLGGYQCLNNFISQNSDINLDVKKFKPNSFNRDDQVALVMFSSGTTGVSKGVMLTHKNIVARFSHCKDPTFGNAINPTTAILTVIPFHHGFGMTTTLGYFTCGFRVALMHTFEEKLFLQSLQDYKVESTLLVPTLMAFFPKSALVEKYDLSHLKEIASGGAPLSKEIGEMVKKRFKLNFVRQGYGLTETTSAVLITPDTDVRPGSTGKIVPFHAVKVVDPTTGKILGPNETGELYFKGDMIMKSYYNNEEATKAIINKDGWLRSGDIAYYDNDGHFYIVDRLKSLIKYKGYQVAPAEIEGILLQHPYIVDAGVTGIPDEAAGELPAAGVVVQTGKYLNEQIVQNFVSSQVSTAKWLRGGVKFLDEIPKGSTGKIDRKVLRQMFEKHKSKL", "output": "Produces green light with a wavelength of 562 nm."}]}
+{"id": "function_valid_4431", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MESDKMMPGGLTEARPATPEIQEIATTVKSQLEEKTNKTYEKFEAVEYKSQVVAGINYYIKVHVGGNSYVHIKVFKSLPYQNKPLELSGYQVDKTKDDELTGF", "output": "This is an intracellular thiol proteinase inhibitor."}]}
+{"id": "function_valid_4432", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGRLILEHTLQGHKGRIWGVAWHPKGNVFASCGEDKAIRVWSLSGNTWSTKTILSDGHKRTIREIRWSPCGQYLASASFDATTAIWSKSSGEFECNATLEGHENEVKSVSWSRSGGLLATCSRDKSVWIWEVAGDDEFECAAVLNAHTQDVKRVVWHPTKDILASASYDNTIKMFAESQLDSDWDCTATLSSHTSTVWSIDFDAEGDRLVSCSDDKTLKIWRAYHPGNDAGIATPDKQSVWKCVCTLSGQHSRAIYDVSWCKLTGLIATGCGDDGIRIFKETSDSKRDEPTFEQLTAEETAHEQDVNAVEWNPAVAGQLISCSDDGTIKIWKVDD", "output": "Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins."}]}
+{"id": "function_valid_4433", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MLIKQLSSSYNEYNNNYAASFLIGPLPEGIAQSLGFNIRSVLLKEFPYFAVKNIRFNPENNNYKTHIGTKESIETIINTILGIDFNYSFDFYKAMGLYKSKPKALFQENLSKAKFLCSAKQVGEGILYAKDLMLPVGIKCTTPYKIIAHVTKQNFLGFTFELGFLFGLNNNIKFENKLYSIKTYPIQNINIEIINSKKSFNLNSESIILSFTTKSSLQPIDVIKILSYLLLNKHLILIKAFQQFLD", "output": "DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates."}]}
+{"id": "function_valid_4434", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRIERVDDTTVKLFITYSDIEARGFSREDLWTNRKRGEEFFWSMMDEINEEEDFVVEGPLWIQVHAFEKGVEVTISKSKNEDMMNMSDDDATDQFDEQVQELLAQTLEGEDQLEELFEQRTKEKEAQGSKRQKSSARKNTRTIIVKFNDLEDVINYAYHSNPITTEFEDLLYMVDGTYYYAVYFDSHVDQEVINDSYSQLLEFAYPTDRTEVYLNDYAKIIMSHNVTAQVRRYFPETTE", "output": "Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis."}]}
+{"id": "function_valid_4435", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDLSQLRPPEGSRKKRKRIGRGSGSGHGGTSCKGHKGQNARSGGGVRDGFEGGQMPLSRRLPKRGFRSRILKDIVTLNVEKLNGFQTGVEIDEHRLKESGMVKSSAEKIKILGKGEIDHPLTVKIKMISQGAKAKIEAAGGSVIEVV", "output": "Binds to the 23S rRNA."}]}
+{"id": "function_valid_4436", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MRDLKTYLSVAPVLSTLWFGALAGLLIEINRFFPDALTFPFFSF", "output": "May help in the organization of the PsaE and PsaF subunits."}]}
+{"id": "function_valid_4437", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MIEVFLFGIVLGLIPITLAGLFVTAYLQYRRGDQLDL", "output": "Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions. PetG is required for either the stability or assembly of the cytochrome b6-f complex."}]}
+{"id": "function_valid_4438", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPLVRVPATTANLGPGFDTLGMALNLFDELKIEESSSPEIIITGEGEGTIPRGQENIAYRAARAVFAKVGRPPVPLKLEMHNSIPVARGLGSSAAALVGAIVGTNAILGGPLGPAELVNLATTLEGHPDNVAPAILGGLVASARDGEQVICRRLELPPGLVTVVAIPQFTLSTRISRGVLPAKVDLEDAVFNISRVAVLLAAVATGDLDLMGRMMVDKLHQPYRLPLIPGMAEVFAAAREAGALAVTLSGSGPTVIAFCRGRQPKVGPAMAAAFARKGVKCTVKELAPCNHGAVVI", "output": "Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate."}]}
+{"id": "function_valid_4439", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAAQQDIRIKLKSYDHTLIDKSAEKIIRTVKSTGAVVSGPVPLPTEKKIYTVLRGPHVDKKSREQFERRHHKRLIDILSSSSDTVDSLMQLELPSGVDVEIKV", "output": "Involved in the binding of tRNA to the ribosomes."}]}
+{"id": "function_valid_4440", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MPNLSGLKTEISSVRNISKITNAMQLVASAKLRKISKKVIDTHNYVSEVYSLFNDIIRQTDKSVFLKESNFKANKTLWVVINSNLGLCGGYNSNVNKLVLQNLKLEDEIFAIGSKAVSFFRSKKIKIKNQITDIDINFTNKKARSISNDLLDMYINHEFDEIKIVYTKFINNVTFEPAIIRIFPIIKLENNFKHSQSLVFEPDAEQILSSTILIYINAIIYGTIIESQVSEQASRRTAMENATNNGKNLEQTLSLKYNRQRQGAITQEISEIVSGANNKS", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex."}]}
+{"id": "function_valid_4441", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSTIAKDQTQINDKIRAKELRLIGQDGEQIGVKSKREALEMAERVDLDLVVVAPNAKPPVARIMDYGKFKFEQQKKEKEMKKKQKIINVKEIRLSPTIEEHDFQTKLKNGRKFLTKGDKCKVSIRFRGRAITHKEIGQRVLEKYADECKDIATVEQKPKMDGRQMFIMLAPTAEK", "output": "IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins."}]}
+{"id": "function_valid_4442", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTSGFALDVRNWTETLGWQPSPQQQQQFEALYHGIIAGNQRLNLTRITDPAEFTEKHLWDSLYGLRPLLTDDWSGEIIDIGTGGGFPGLPAAIALTKSRVMLLDSTRKKIQFLQTLAQELGLSNVTVAVGRAEEWGRDRRQRARYDWATIRAVGPATVCAEYCLPLLKIGGKAVLYRGQWTEEEAIALDRAVTILGGEVVDVSATFLPESGAERHCITLQKTAQTPAAYPRMVGLPSQKPLG", "output": "Specifically methylates the N7 position of a guanine in 16S rRNA."}]}
+{"id": "function_valid_4443", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MARSGYTLPVFACAAAIAALQRLRQPAASIQSVDCHLIDPDQTVAIAIEQVAPLSPDRALAICRSDPGDNLDLTRGTPIWAEVQLSPRSPDQDSLAIEAGEGIGHSETGPAIYDYAQRLLRANLLPLLQTNEQLTVRLILPEGRRLAERTANAAFGVVEGLSLLGTHGVAEALSAPEQLQVFRDRLRQLSADPDLVIFCIGENGLDLSQKIGLPRDRQLKTANWLGPLLVEAGLLGIPRILLFGYHGKLLKLAGSIFHTHHHVADARREILAAYAIAAGASLEQVRSLLDFPTVDAATQYLDQTDPALASRLWPQIAEAIVDRSQAYIRRYSEQIPEIGVVLFGRDRQLLTASSQAQTWLTNRAIAQPLRYPSA", "output": "Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A."}]}
+{"id": "function_valid_4444", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKLHVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL", "output": "One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA."}]}
+{"id": "function_valid_4445", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSEIILNANAQDVADARANGLSEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGGVLDSGLRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQDALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHIYVDESVEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQMAESGVTLHADAAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIREHGTQHSDAILTCDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLEALTTYKWIGIGDYTIRA", "output": "Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate."}]}
+{"id": "function_valid_4446", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKRISTTITTTITITTGNGAG", "output": "This protein is involved in control of the biosynthesis of threonine."}]}
+{"id": "function_valid_4447", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSRRSTNEGRLTRPNPVYRNRLVNMLVNIILKNGKKSVAYRILHEAMKTIQQKTKKNPLAVVRQAIRRVTPNVAVKARRRGGSTYQVPVEIKPDQGKALAVRWILAAARKRPGRSMAFKLSYELMDAARQTGNAIRKREETHRMAEANKAFAHYR", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit."}]}
+{"id": "function_valid_4448", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSLMTKLGFRALVASCLITAGSAANAQVNVLITGVGSTQFPIATANFANEANLPQQVTSIVRADLARSGKFTNIDAGSTPVPESASVDLGAWKAKGANAFVAGSVNREANGQYKVNFILYDTVKQQSLGGLSLTATDTTLRTAGHKIADYIYQKLLGVRGVFATRLSYVIKTGNRYQLQISDSDGQNARIALSSTEPIISPSWSPSGTKVAYVSFERKKPIVYIHDLPTGRRYIVSDQKGNNSAPAWSPDSNTLAVALSLTGNTQIYTVNSTGGGLRRLTQSSSIDTEPFYSPDGHWIYFTSDRGGAPQIYRMPAQGESAGAAQRVTFTGSYNTSPRISPDGKLLAYISRTGGGFKLYVQDLQSGAANAITNTNRDESPSFAANGQYLLYATQSGGRNVLAAVPSDGSAPPQILSVQGGSVREPSWGPFMQ", "output": "Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity."}]}
+{"id": "function_valid_4449", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTQEREKAIELALSQIEKQFGKGAIMRLGADEALPDIDAIPTGALSLDIALGVGGVPRGRVIEIYGPESSGKTTLALHIAAEAQKLGGIAAFVDAEHALDIGYARKLGVRTDDLLVSQPDTGEQALEIAEMLVRSGAVDVLVIDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGIISKSNCCVIFINQIRMKIGVMFGSPETTTGGNALKFYASVRLDIRKIATLKQGDAVIGSRTKVKVVKNKVAPPFREVEFDIYYGEGISRLGDLLDLAVDRKIIDKSGAWFSYGSDRIGQGRENSRNFLKEHPEMVAEIEDKIYETAGIPRKGGKEEAA", "output": "Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage."}]}
+{"id": "function_valid_4450", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDQHKGDASLGGIVKALGLVFGDIGTSPIYTLTVIFTLTQPTRENVFGILSLVFWTMTILVTMEYAWLAMSLGRKGQGGEIVLREIIMKLVKTGRLVAFAGFLSFVGVSLLLGDGVITPAISILSAVEGLLLIPGLEGLSTGTLVAIAAAIAIGLFSVQFKGTDRVAGAFGPIMAVWFSTLAVTGVVSALSMPEIVEAINPWHAFTFFRENGLAGYFVLSEVILCSTGGEALYADMGHLGRRPIVKSWYFVFMALYLNYLGQGVFAITHPEAKNLLFGMVRDQMPTLYIPFLILTIMATIIASQSIISGVFSIVYQGITTRLLPLMRVDYTSREIKSQIYLGAVNWSLMVAVILVMLLFRKSENLAAAYGMAVTGSMTITGIMMIIVFAHTTKKWRALVALVITLIDAAYLLSTFSKIPHGAYWSLILASIPFVTIIIWTRGQRSLYHALKPLDLETFLISYEQIYAKGPIRGTGLFFTRDTDVVPPYVVHCIIRSNIIYERNVFISLVITDEPLGVETELIKGIGPGLDAFRIEAGYMEVVDIEALLKANGIQEKVIFYGVEDISTRNPLWRVFSVFKKLTPNFVQFHKLPASRLQGVVTRVEM", "output": "Transport of potassium into the cell. Likely operates as a K(+):H(+) symporter."}]}
+{"id": "function_valid_4451", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MQIKSAEFIKSAAKPVGYPPGDLPEVAFAGRSNVGKSSLINVLVNRRGLVRTSSTPGRTQLLNFFEVNQHFMLVDLPGFGFAKVPVSVKKAWGRMTRTYLEERTNLKAVVLLFDIRREPRDEELQLLDWLEELNIPTIPVITKVDKVTKNRRRAQIRPILEATGLPQEAFSFFSALTREGREDILQRLDVALSDVEDEFGIDVPESE", "output": "Necessary for normal cell division and for the maintenance of normal septation."}]}
+{"id": "function_valid_4452", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTESTTSDVVLTSEQIAGLLPHRYPFALVDRVIAHDPGVSATAIKNVTMNEPQFQGHFPERPLMPGVLIVEAMAQVGGLIVTQMPDLPKGLFVFAGIDGVRFRRPVVPGDQLVIRCELLSLKRKRFGKVKAEATVDGDLACSGELMFSLVD", "output": "Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs."}]}
+{"id": "function_valid_4453", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTKYISALGLDVGRKRVGVAGCDRTGLIATGITTVERTSFDRDVQQIQNIVNERQVQVLVVGLPYSMDGSLGFQARQVQKFTSRLAKALQLPVEYVDERLTSFQAEQMLIAENVSPSRNKGLIDRKAAALILQQWLDIRRTNAQSSVAVEY", "output": "Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA."}]}
+{"id": "function_valid_4454", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MGIKNLNSVTASLRGTVLLDKSMLWKGKPEKSLVSYKISCGGRNSRGVITVRHRGRGHKRLYRIIDFKRNKVGVSATVERLEYDPNRTAFIALLSYDDGEKSYIIAPNGLKKGDVVISGEGSDILPGNCLMLKSIPVGTFVHNVELRPGNGGVIARSAGTYAQLMSKDGVYVLLRLSSGEIRKVLSDCRATIGIVSNLDNQNVKLGKAGRNRWLGIRPTVRGVAMNPIDHPHGGGEGKTSGGRNPVTPWGVPTKGKKTRKRNKSSNKYIKRVSDKG", "output": "One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome."}]}
+{"id": "function_valid_4455", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSIDVANESGVPADEERLARLARYILDALRVHPLAELSVLLVDEEPMADLHVRWMNEPGPTDVLSFPMDELRPGAPGRTSEPGILGDVVICPQVAARQAERAGHSMQDEIDLLCTHGILHLLGYDHAEPDEHREMFSLQNELLAGWRRSLEEEER", "output": "Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA."}]}
+{"id": "function_valid_4456", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTRSLKKNPFVANHLLRKIEKLNTKAEKEIIITWSRASTIIPTMIGHTIAIHNGREHLPIYITDRMVGHKLGEFSPTINFRGHAKNDNRSRR", "output": "Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA."}]}
+{"id": "function_valid_4457", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIESNLIISLLVIPMITIIALIFIGKRPKIKRYVALAGTALTLIFAFINLNNVLKDGPITLELGSWDAPYSIVFVLDIFSALLVITSLIVTMLIILYSYQSVGIERETYYYYFAVMFMLTGVIGSFITGDIFNLFVFFEVFLMASYILLVIGGTKVQLSETIKYVLVNVTSSAFFVIAVAMLYSVVGTLNLADISEKLSQLPSQDSGIVTIIFILFIFVFATKAGAFPMYIWLPGAYYAPPIAIIAFFGALLTKVGIYAIARTASLFFRDTSNFSFYTILFLALLTIIFGCVGAISYFDTKKIILYNIMIAVGVILVGVAMMNQTGMMGAIYYTLHDMLIKAALFFLIGVMYKITKTHDLRKYGGLIKDYPVLGWTFFIAALSLAGIPPLSGFYGKYYIVQATFEKGFYLSGIVVLLSSLVVLYSVIRIFLQGFFGKSEGYQVNPKLQYKGILTVSIVAVVISVIFGLSADWLQPIIKDAAETFYNPSVYTDSVLGGK", "output": "Mnh complex is a Na(+)/H(+) antiporter involved in Na(+) excretion."}]}
+{"id": "function_valid_4458", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKIDFLTLFPEMFNGVLNQSILKRAQDKNMLTVNTVDFRHFAENKHNQVDDYPFGGGQGMVLKPEPIFNAMESIEKTDDTRVILMCPQGKPFTQAIANELSQSEHVVFICGHYEGYDERIREHLVTDEISMGDYVLTGGELPAMVMTDAIVRLLPGVLGNQQSHEDDSFQDGLLEFPQYTRPREYKGMSVPDVLLSGNHAHIDRWRHEQKILRTFVKRPDLLERYPMTVEEKDIVERYKKQLKKD", "output": "Specifically methylates guanosine-37 in various tRNAs."}]}
+{"id": "function_valid_4459", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSQKAIKGYINLIIPAGGATPAPPIGPALGQRKVNIKTFCDEFNNSTKDTEKGVPLPTLITVYEDSSFSFKIKTPPASYFLKKYARITKGSSATKKEAVVGKVTMDDCREIAKLKMPDLNTKDIEAATKIICGSAASIGLEVVGN", "output": "Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors."}]}
+{"id": "function_valid_4460", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTQSNPNEQNVELNRTSLYWGLLLIFVLAVLFSNYFFN", "output": "One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation. This subunit is found at the monomer-monomer interface and is required for correct PSII assembly and/or dimerization."}]}
+{"id": "function_valid_4461", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSRLEHRFAQLKTEGRAALVTFITAGDPGYDTSLKVLKGLPAAGADVIELGMPFTDPMADGVAIQLATLRALDAGQTLQKTLQMVSEFRVDDQTTPIVLMGYYNPIHRFGVEAFVAQAKEAGVDGLIIVDLPPEHDAELATPAQASGIDFIRLTTPTTDDARLPRVLERSSGFVYYVSVAGVTGAGSATTEHVTEAIARLRRHTDLPISVGFGIRTPEQAAAIARLADGVVVGSAFVDKIASAESPEHAIDGVLTLCAALAEGVRSARR", "output": "The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate."}]}
+{"id": "function_valid_4462", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MQRSLDSLAGMATSAFGAGTSAAMRQATSPKTILEYIINFFTCGGIRRRNETQYQELIETMAETLKSTMPDRGAPLPENIILDDMDGCRVEFNLPGENNEAGQVIVRVSKGDHSETREIPLVSFEKICRALLFRCEFSLPQDSVILTAQGGMNLKGAVLTGANLTAENLCDADLSGANLEGAVLFMADCEGANFKGANLSGTSLGDSNFKNACLEDSIMCGATLDHANLTGANLQHASLLGCSMIECNCSGANMDHTNLSGATLIRADMSGATLQGATIMAAIMEDAVLTRANLRKASFISTNLDGADLAEANLNNTCFKDCTLTHLRTEDATMSTSTQTLFNEFYSENI", "output": "Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. Involved in the reorganization of late endosome/lysosome (LE/Lys) compartments in mammalian cells. Necessary and sufficient to link kinesin-1 onto the Salmonella-containing vacuole (SCV) membrane. Required for centrifugal extension of lysosomal glycoprotein-rich membrane tubules, known as Salmonella-induced filaments (Sifs), away from the SCV and toward the cell periphery. Required for virulence, but not for intracellular survival and replication in phagocytic cells (By similarity)."}]}
+{"id": "function_valid_4463", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDYFTLFGLPARYQIDTQALSLRFQDLQRQYHPDKFANGTQAQQLAAVQQSATINQAWQTLRHPLTRAEYLLSLHGFDLASEQHTVRDTAFLMEQLTLCEELDDIEQSKDDVRLESFIKRVQKMFDARLQQMVEQLDNAAWDAAADTVRKLRFLDKLRSSAEQLEEKLLDF", "output": "Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA."}]}
+{"id": "function_valid_4464", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MAGDLNLKKSWNPALVKNQQKVWEEEQQKLDELKRIKERNQEYKQEQEYLELLKLQHGDQFQIKDLNKQQKLKISKLNWMYDDVPFEGNEKVEENSSGFIESNVEFTDGKSKVENLLKGNHVVGKKRDGSGTSDRINKIIGVGMTKSSKVSYSDDPLLKIKQQQQQAQRVARKQHPSDKHSHRSRHSSKSSSDRVHKSHEHERSRKHNSSHTRHKDGSPHR", "output": "Involved in pre-mRNA splicing."}]}
+{"id": "function_valid_4465", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MACGATLKRSMEFEALMSPQSPKRRRCAPLPGSPATPSPQRCGIRPEMQQGQQQPLPQLGGDRRLTPEQILQNIKQEYTRYQRRRQLEGAFNQSEAGVSNEVQASCSSLTAPSSPGSLVKKDQPTFSLRQVGILCERLLKDHEDKIREEYEQILNIKLAEQYESFVKFTHDQIMRRYGARPASYVS", "output": "Molecular adapter that acts as a bridge between proteins, and which is involved skeletal muscle development. Functions as signal transducer for MSTN during skeletal muscle regeneration and myogenesis."}]}
+{"id": "function_valid_4466", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSGSAKYSDWSQVMTLIANAAEQGNHQPLLTMLMTPDEREALVARVNIFHELLQGELSQRQISQLLGVGVATITRGSNELKSHTDEEKVWLMDLLEKSTKSELDVEKE", "output": "This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription."}]}
+{"id": "function_valid_4467", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MEYDIKTLDNGSAGSVALPEEIFAVTPRSDIMARVVHWQLAKRRAGTHRTKGMGEISGTTKKPYRQKGTGSARQGSLRAPQFRTGGVVHGPVVRDHGYDLPKKVRRLGLICALSQKAAEGKLIVLDAANGVTKTREAAAKIKALGWTSALIVDGAVDEQFARAIANLPKIDVLPTIGANVYDILNHDVLVITRAGLEGLKERLA", "output": "One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.; "}]}
+{"id": "function_valid_4468", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MAEQASSFTDRLAARFAGAQIAVALPRGEVTLEVAAADWHATCLALRDELGFEQLSDLCGVDYLGYGSGEWDTADVSSQGFSRGVEGKAVGRFAWGEFPSQESSAGAQPQQLPKQRFAVVAQLISYQHNQRLRVRCYAPDEQVPLVASVTDIWPGVNWFEREAFDLFGIVFDGHPDLRRILTDYGFVGHPFRKDFPLIGNVEVRYDEERKRVVYEPVTSVEPRVGVPRVIRDDARYETAAGEVGRSETAK", "output": "NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient."}]}
+{"id": "function_valid_4469", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSRHYEVVFLVHPDQSEQVPAMIERYKSLIEGGNGTIHRLEDWGRRQLAYPIQNLVKAHYVLLNIEVDQAVLSELVESFRFNDAVLRHLVVKRDGPDTEQSLIMKSKDEKGDKHERSERRRRDDEEGDVPAATDTDGDNAEAA", "output": "Binds together with S18 to 16S ribosomal RNA."}]}
+{"id": "function_valid_4470", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MARREEETKEFEERVVTINRVAKVVKGGRRFRFTALVVVGDKNGRVGFGTGKAQEVPEAIKKAVEAAKKDLVVVPRVEGTTPHTITGQYGSGSVFMKPAAPGTGVIAGGPVRAVLELAGITDILSKSLGSNTPINMVRATINGLQNLKNAEDVAKLRGKSVEELYN", "output": "With S4 and S12 plays an important role in translational accuracy.; "}]}
+{"id": "function_valid_4471", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKPLHIVMENFGPFIKETIDFEQVETDQLFLISGKTGSGKTMIFDAIVYALYGMASTKTRKEGDLRSHFADGKSPMSVIYQFKVNNQTFKIHREAPFIKEGNITKTQAKLNIYELVDNQFELRESKVNQGNQFIVQLLGVNAEQFRQLFILPQGEFKKFLQSNSKDKQSILRTLFNSERFDEIRHLLVENVKQEKVQIENRYTQIENLWNDIDTFNNDELALYKELESSQTDKMIEKFPQFNDYGCKILKSFEEAKNKITKELDDLNHKYKVNVELSENTKKLKAEKIKFDDLKKEQNYIDKLKQELKMIQESKVLITYFTRLQSLKKDKDELVSLHEQSKLNETNYHNEIKGFQKQLEHLSTRENEITQFNQYLEKNQVFFNQLDKIISSYQQKPVIEEEIKRLYSEYNDLITKKEELTKEMNNKNKDFAIIEHYTEEIYKLKKIIDESERQKKDEKLFDKLQLDKSSYLSKLKEKKEQLNEIESSITNIDATLIDLNDKKDFVNEIKSAMSIGDTCPICGNEIHSLGEHIDFESIAQKNNKIKRLESKKVKIRDEIIKIETRIEELNHRENELNFEKQEKKDISELQKQLNHLNQLKDEQQSINKLVENFEKQEKEIVNKIHQFDLDLSRKNTQKEKLEIQINDFERHSQFSSVNDFETYYSHAKKQVETYEYENEKTKDKLNELNNKLKIEMNDQKHLTENLTQTSKEINNLELKMEKEMQQLGFESYDQVKSAADLSAQKDEIEREINIYNKNYQSYEIEINRLKELVKGKKLLNLEELRQSIEKTNLKLDETNSQIATISYKIDNNSNKFNKIKNIIQILDDELKVQKEIFLLSEILAGKNDYKLTLENYVLIYYLEKIIFQANQRLSFMSGNRYQLIRREAISLGLSGLEIDVFDFHSNKSRHISSLSGGETFQASLALALGLSEVVQQESGGITLDSMFIDEGFGTLDQETLETAIDTLINLKSSGRMVGIISHVSELKQRIPLILEVTSNQYESHTQFRKN", "output": "SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity (By similarity)."}]}
+{"id": "function_valid_4472", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKIDILTLFPDMFAPLEHSIVGKAKDKGILEINYHNFRDNAEKARHVDDEPYGGGQGMLLRAQPIFDTFDKLNVTKPRVILLDPAGRTFNQAYAEELAQEEELVFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTIVDATVRLIPEVLGKEASHKDDSFSSGLLEFPQYTRPAEFRGMKVPDVLLSGHHVNIRRWRMEQSLRKTWERRPDLLENYDFTDEERQILEEIKSEGK", "output": "Specifically methylates guanosine-37 in various tRNAs."}]}
+{"id": "function_valid_4473", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLSLLPYTDRHQ", "output": "Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit."}]}
+{"id": "function_valid_4474", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSAFTPASEVLLRHSDDFEQSRILFAGDLQDDLPARFECAASRAYTQQFHHWQALSRQMGDNVRFSLVAQASDVADCDTLIYYWPKNKPEAQFQLMNILSLMSVGSDVFVVGENRSGVRSAEPMLADYAPLNKVDSARRCGLYHGRLEKQPQFSLESWWAEYNIDGLTIKTLPGVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGCGAGVLSAALASHSPKVRLTLCDVSAPAVEASRATLAANGLEGEVFASNVFSEVKGRFDMIISNPPFHDGMQTSLDAAQTLIRGAVRHLNSGGELRIVANAFLPYPKILDETFGFHEVIAQTGRFKVYRTVMTRQAKK", "output": "Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle."}]}
+{"id": "function_valid_4475", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDEWIAEFIKRIILKLPFSQTMTILKAWGFLTDSELQTLTLRYPKDITATEVVRLCEAKNATIDHAAALDFVFNHAFSNKKLWTVYQMSKTSESENDLFDASEFKLQFKKSIHAVSKNVTINFKEFGEALWIRIAWGTHNTRPNQYKATFAVYHSQTPHVFITGLGKACRPLLCQALVIASKYSQIQEMELKSRCLESLKDIVFKRFNQPFSSHHSRPHEKALTQKIVDPRVTYENMREKERVHHLTRETFGEGPLPKLELASYKLETMFRAESIMGGNLTAGNEPFRCVVKFSSPHLLEAIRSLAPAGIAEAPISTLLSCIPHKARNSFKITEKRGLHPASSQPTNF", "output": "Probable component of a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation."}]}
+{"id": "function_valid_4476", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MAGQISETDQIKQFKEFLGTYNKITENCFMDCIRDFTTREVKPEEITCSEHCLQKYLKMTQRISMRFQEYHIQQNEALAAKAGLLSQPR", "output": "Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space (By similarity)."}]}
+{"id": "function_valid_4477", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MNRKKGDKGFESPRPYKLTHQVVCINNINFQRKSVVGYVELTIFPTVANLNRIKLNSKQCRIYRVRVNDLEAAFIYNDPTLEVCHHESKQRNLNYFSNAYAAAVSAVDPDAGNGELCIKVPSELWKHVDELKVLKVHINFSLDQPKGGLHFVVPNMEGSMAERGAHVFSCGYQNSTRFWFPCVDSYSELCTWKLEYTVDAAMVAVSNGDLVETVYTHDMRKKTFHYMLAIPTAASNISLAIGPFEILVDPYMHEVTHFCLPQLLPLLKHTTSYLHEVFEFYEEILTCRYPYSCFKTVFIDEAYVEVAAYASMSIFSTNLLHSAMIIDETPLTRRCLAQALAQQFFGCFISRMSWSDEWVLKGISGYIYGLWMKKTFGVNEYRHWIKQELDQIVAYELKTGGVLLHPIFGGGKEKDNPASHLHFSIKHPHTLSWEYYTMFQCKAHLVMRLIENRISMEFMLQVFNKLLSLASTASSQKFQSHMWSQMLVSTSGFLKSISNVSGKDIQPLIKQWVDQSGVVKFYGSFAFNRKRNVLELEIKQDYTSPGTQKYVGPLKVTVQELDGSFNHTLQIEENSLKHDIPCHSKSRRNKKKKIPLMNGEEVDMDLSAMDADSPLLWIRIDPDMSVLRKVEFEQSDFMWQYQLRYERDVVAQEEAILALEKFPTPASRLALTDILEQEQCFYRVRMLACFCLAKIANSMVSTWTGPPAMKSLFTRMFCCKTCPNIVKTNNFMNFQSYFLQKTMPVAMALLRDVHNLCPKEVLMFILDLIKYNDNRKNKFSDNYYRAELIDALANSVTPAVSVNNEVRTLDNLNPDVRLILEEITRFLNMEKLLPSYRHTITVSCLKAIRVLQKNGHVPSDPALFKSYAEYGHFVDVRIAALEAVVDYTKVDRSYEELQWLLTMVQNDPVPYIRHKILDMLTKNPPFTKNMESPLCNEALVDQLWKLMNSGTSHDWRLRCGAVDLYFTLFGLSRPSCLPLPELGLVLNLKEKKAVLNPTIIPESVANNQEPVNTTNNHGQPVVFQNTEDDHLIKETASSISGHQQGVKRKADMPLGSPLEPGQILEKNEDSKVKLKIRFSNSQEEEEIDMDTVHDSQAFIYHHLNMLERPSTPGKEQSSGEVTMHPVSAAPLSVFSKESNSSKHSDHHHHHHHEHKKKKKKTLQVWIRP", "output": "The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs)."}]}
+{"id": "function_valid_4478", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MAASIPSDLRNLRACLLCSLIKSVDAFQTDGCENCDEVLHLKGDEEKVYDCTSANYDGMIAAMSNDDSWVCKWQKMQRRVKGIYAISVSGSLPSNVVSDLKSMGVRYKANQRDYSIQAKK", "output": "May function as a component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II. DSIF may enhance transcriptional pausing at sites proximal to the promoter, which may in turn facilitate the assembly of an elongation competent RNA polymerase II complex (By similarity)."}]}
+{"id": "function_valid_4479", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGIKKYNPTTNGRRNMTTNDFAEITTDRPEKSLLAPLSKKAGRNNQGKITVRHQGGGHKRQYRIIDFKRNKDGIPGRVATIEYDPNRSANIALINYVDGEKRYILAPKNLEVGMEIMSGAEADIKIGNALPLINIPVGTVVHNIELKPGRGGQLVRSAGTSAQVLGKEGKYVLVRLTSGEVRLVLSACRATVGQVGNESHELIKIGKAGRSRWLGKRPTVRGSVMNPVDHPHGGGEGRSPIGRKSPMSPWGKPTLGFKTRKKNKASDKFIVRRRKK", "output": "One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome."}]}
+{"id": "function_valid_4480", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTTSPTPFKTVRDLVRHAVSRFSQAKLAFGHGSDNAFDEAVYLVLHTLHLPLDTLEPFLDARLAPDEIDAVLAVIERRATERVPAAYLTREAWMHGHRFYVDERVIVPRSFIGELLDDGLQPYVEDPELVGSVLELCTGSGCLAILAALAFPNASVDAVDLSADALAVAKINRDNYGLDERIALYHGDLYAPLPQFKWIDPAQRYDVIIANPPYVNAGSMAELPAEYRHEPEMALAGGADGMDIVRRIIGEARRWLQDDGVLVVEIGNERANVEAAFGGLELVWLPTSAGDGSVFLIHASELPAVAG", "output": "Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue."}]}
+{"id": "function_valid_4481", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSAPPKENIGLPVSEFVQMNNLACESVGGKVLFATDDCFAPAENLLKKKDPEFKPGLFTEFGKWMDGWETRRKRIPGHDWCIIELGVPGIIHGFEADTRFFTGNYAPRISVQAACLKPEEITFQPRKDKIGTAASIEEYKSADKLKSEKWSHLLQMTELTPGYAESSHSYFNVNSKQRWTHLRLNIYPDGGIARFKVYGIGQRDWSSCKPNDLEDLLSMVNGGVCLGFSDAHYGHPRNLIGIGRACDMGDGWETARRLDRPPVLKADSKGILQVPGFEWAVLKLGHPGLVTHIEIDTNHFKGNSPNSCKIDACALTPTEEEGVKRDERFEIGYNWKPLLSVTQIHPHKRRYVESTSLALHQVISHVKITIAPDGGVSRIRLWGFPRPLP", "output": "Utilization of purines as secondary nitrogen sources, when primary sources are limiting."}]}
+{"id": "function_valid_4482", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKTDLLACRHIGVNKADAEVMLRKIGVASLDELIDKTIPANIRLKAPLALPAPMTEYEFARHIAELAGKNKLFTTYIGMGWYNTITPAVIQRNVFENPVWYTSYTPYQTEVSQGRLEALMNFQTAVCDLTAMPLANCSLLDEATAAAEAVTMMYGLRSRNQQKAGANVVFIDENIFPQTLAVITTRAIPQDIEIRTGKFRDLEFTDDLFACVLQYPNANGNAEDYREFTEKAHTANCKVAVAADILSLALLTPPGEWGADIVFGTTQRLGTPMFYGGPSAGYFATRDEYKRNMPGRIIGWSKDKYGKLCYRMALQTREQHIKREKATSNICTAQALLATMAGFYTVYHGQEGIRNIASRIHSITVFLEKSISKLGFKQVNKQYFDTLRFILPDSVSAQQIRTIALSKEVNLRYFDNGDVGLSIDETTDVAAANILLSIFAIAAGKDFQKVDDIPEATIISEELKRQTPYLTHEVFSKYHTETEMMRYIKRLDRKDISLAQSMISLGSCTMKLNAAAEMLPLSCAEFMCMHPLVPEDQAAGYRELIHNLSEELKVITGFAGVSLQPNSGAAGEYAGLRTIRAYLESIGQGHRNKVLIPASAHGTNPASAIQAGFTTVTCACDEHGNVDMDDLRAKAEENKDDLAALMITYPSTHGIFETEIVEICQIIHACGAQVYMDGANMNAQVGLTNPGFIGADVCHLNLHKTFASPHGGGGPGVGPICVAEHLVPFLPGHGLFGNSQNEVSAAPFGSAGILPITYGYIRMMGAEGLTMATKTAILNANYLAACLKDTYGIVYRGANGFVGHEMILECRKVYEETGISENDIAKRLMDYGYHAPTLSFPVHGTLMIEPTESESLSELDNFVLTMLTIWNEIQEVKNGEADKEDNVLINAPHPEYEVVSDQWEHCYTREKAAYPIESVRENKFWVNVARVDNTLGDRKLLPTCYGCFD", "output": "The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein."}]}
+{"id": "function_valid_4483", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MDTETSPLLSHNLSTREGIKQNTQGLLAHTIARHPGITAIILGILILLVIILIIVAIVYYNRSVDCKSNMPRPPPSYSIQQSEPHHHFPVFFRKRKNSTSQQAHIPSDEQLAELVHS", "output": "Together with the penton and the other minor capsid proteins (M1249L, p49), forms a complicated network immediately below the outer capsid shell, stabilizing the whole capsid. Three copies of p17 encircle each p72 capsomer in the inner capsid shell, anchoring p72 capsomers on the inner membrane. Required for the assembly of the capsid and icosahedral morphogenesis. Additionally, inhibits the host cGAS-STING pathway through its interaction with STING1 and subsequent interference of the recruitment of downstream components TBK1 and IKBKE."}]}
+{"id": "function_valid_4484", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MWKEFKSFAIRGNVIDLAIGVIIGGAFGKIVTSLVNDLMMPLLGLLLGGLDFSALSFTFVDAEIKYGLFIQSIVNFFIISFSIFLFIRYISKLKKKDAEEEKAAPDPQEELLKEIRDLLKEQTNRS", "output": "Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell."}]}
+{"id": "function_valid_4485", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEKKIALIAHDKKKDDLVNFVKQNYLFLSKFKLIATGTTGSRIQQATDLTIIKYKSGPMGGDQQIGAEVAEGNVLAIFFFRDPLTNQPHEPDVSALIRLCDVHNIPLATNVKTAEILIKGFEGLNT", "output": "Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate."}]}
+{"id": "function_valid_4486", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSENTAERTTRRKVREGLVVSDKMNKTITVMVEDRVKHPLYGKVMTKSVRLKAHDENNEAGMGDRVRIMETRPLSATKRWRLVEIIEKAK", "output": "One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA."}]}
+{"id": "function_valid_4487", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTKHSGIDPLTQISPNQHVLIRLPSDNLKIVELKANAIVSLGKFGAFRVNEIIGYRFGTTFDIVYDGVEEEFVKGTQTMIGKISVLENRLKASSPALENSSENNRGLINLGSVVQEMSMAEIEAMKREAASGDAIISKMIESHKSFHQKTVHSQEKYLKRKKQKFAKFFTVEYLDSSGLLHYLIEKGDVLRVMDISQESLGMALNLANINSNGQYLCIDETGGLIVYAMLERMFAGDSNSKANGKIVVVHENEHPNLDLLKFSSYSDNFIQRHVKTISVLDFFEPAKEADIKSLFKPLSAEEINDLKSNKKSAYFRRLKWYHNQLSNIEVAASSFDGLLVASTLYLPTLIPRLGEKIHGSRPIVCYSQYKEPLLELSHSLYENLNYLAPSLLETRCRPYQTVRGKLHPLMTMKGGGGYLMWCHRVLPAAEPKLHQETLEKSEIKNSDEEGDEDAHKLDQEKQVIKRRKPNEDNEKL", "output": "Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA."}]}
+{"id": "function_valid_4488", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MFRPLVKRVVTRRFLAAANNSNAHIEIRTLEDLAKLQSLDNVDPKLISKLINDKTNELNIKNELQMLKQLQAEEQKTQETSLKKFVRPAWIFLLMGSIVYLSCHYVWWKLDYEEKELEYTHKVHQLESELAALNEAHNSSVSSDKNSKRSSRKWYKFW", "output": "Component of the INA complex (INAC) that promotes the biogenesis of mitochondrial F(1)F(0)-ATP synthase. INAC facilitates the assembly of the peripheral stalk and promotes the assembly of the catalytic F(1)-domain with the membrane-embedded F(0)-domain."}]}
+{"id": "function_valid_4489", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKIGVFCPIGNNGWLLSENAPQYMPSFELNKKIVQRAEHYGFDFALSMIKLRGFGGKTEFWDHNLETFTLMAGLAAVTSKIKIYATAATLVMPPAIVARMASTIDSISNGRFGLNVVTGWQAPEYSQMGMWPGDEYFAKRYEYLSEYVQILRELWATGQSDFKGEHFQMEDCRVSPQPQAEMKIICAGQSDTGLEFSAQHADYNFVFGKGLNTPTAYAGINDRLKHFTDQTGRDVQTYVLFMVIAAETDAEAMAKWQSYNDGADVEAINWLMNQGGKDTKSGADTNIRQMASSVSPVNINMGTLVGSYEKVAAMLDEIAEIKGTEGILLTFDDFVQGVEDFGERIQPLMTSRQDIVAEYQPVTPLEKSA", "output": "Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism, adding oxygen atoms in the process to yield ureidoacrylate peracid, that immediately reacts with FMN forming ureidoacrylate and FMN-N(5)-oxide. The FMN-N(5)-oxide reacts spontaneously with NADH to produce FMN. Requires the flavin reductase RutF to regenerate FMN in vivo."}]}
+{"id": "function_valid_4490", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MRVVFQQCTKFSTSCNRAFLARFLKPVMNASPKEHVVKQLLKPVGLNVPPRPNIKYSEGNSWLDLFDGAKTEERIKELEIEFAKSGMYEMATFRKTNGKLFLSPESYWKADKALYFPHLSGRTLSSEDHGNVEDVLRGKTSVIRVFSTQVGDKISREYIKNTELGIDNYENQSCQVIDINFLENKLKSWLFKLSLNNLKSTVPVQRHDNYWLCHREQIPFLMRERLLINNVYSGYIFVVDPNLKIRFMACGPASADEFNKLWKVVGQLSKEKK", "output": "Involved in assembly of the mitochondrial F1-F0 complex."}]}
+{"id": "function_valid_4491", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPRKGSVPKRDVLPDPIHNSKLVTKLINKIMLDGKRGTAQRILYSAFDLVEQRSGRDALEVFEEAINNIMPVLEVKARRVGGSNYQVPVEVRPERRTTLGLRWLVNYARLRGEKTMEDRLANEILDAANNTGGAVKKREDTHKMAEANKAFAHYRW", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA."}]}
+{"id": "function_valid_4492", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSNVLELTIPASTANLGVGFDSIGMALDKFLHLSVKETSGTKWEYIFHDDASKQLPTDETNFIYHVAQQVAAKYSVDLPNLCIEMRSDIPLARGLGSSASALVGAIYIANYFGDIQLSKHEVLQLATEIEGHPDNVAPTIYGGLIAGYYNDVTKETSVAHIDIPDVDVIVTIPTYELKTEASRRALPQKLTHSEAVKSSAISNTMICALAQHNYELAGKLMQQDGFHEPYRQHLIAEFDEVKTIASQHNAYATVISGAGPTILIFSRKENSGELVRALNRNVVTCHSELVDINVSGVKERIVYQ", "output": "Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate."}]}
+{"id": "function_valid_4493", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKTFPVSIVTPDGPVYEKEVEMVSVKAESGEMGILPGHIPTVAPLKISAVRLKNGGHTDYVAVSGGFIEVRPDKVTVLSSSAEEANHIDIHRANEAKRRAEQRLQDKQAHVDFKRAEMALQRAVNRLNVSDMK", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane."}]}
+{"id": "function_valid_4494", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MADITVELVSVERMLWSGKASIVTAQTVEGEIGVLPGHEPLLAQLVDNGVVTIRPVDGDKLVAAVQGGFLSISKEKVTILAEYAIWADEVNTAESESHLQADDEISKARAEAELKAVRRKAEA", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane."}]}
+{"id": "function_valid_4495", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MANTEFYFNVDSGYLEGLVRGFKGGILRSTDYLNLAQCETLEDLKLHLQSTDYGSFLANETRQLTVSIIDQRLKDKLMAEFHYFRNHAFEPLATFLDFITYSYMIDNIILLITGTLHQRPISELVPKCHPLGSFEQMEAVNIAQTPAELFNAIIVDTPLADFFQDCLSENDMDEMNIEIMRNKLYKSYLEAFYKFCKKLGGTTEEIMCPILEFEADRRAFVITINSFGTELNKEEREKLYPTCGRLFPEGLRMLGNADDQDQVKTTAEYYAEYKALFEGVGIGTGEKTLEDKFFEHEVKMNVLAFNNQFHFGVFYAYVKLKEQECRNIVWIAECISQRHRTKINNYIPIL", "output": "Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). May play a role in coupling of proton transport and ATP hydrolysis (By similarity). Regulator of osteoclast fusion and bone formation (By similarity)."}]}
+{"id": "function_valid_4496", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSEQKTLSVQKRDNLGKGANRRLRSEEVVPGVFYDTKGNNVAVQMPAKPLQKLFEEVGRTTVFQLEIEEEGKKSTHPVLIWDALFHPYKKKFTHIDFFGVDLDREIKIRVPLEFVGTSRGVKLGGKLEVYREFIDVMSKPLTLPKKITLDLTELDINSTIMLKDVAMPEGVRPATNENFAILSVLTPKSE", "output": "This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance."}]}
+{"id": "function_valid_4497", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MSLFDHSVSELHKKLNNKEISVTDLVEESYKRIADVEDNVKAFLTLDEENARAKAKELDAKIGAEDNGLLFGMPIGVKDNIVTNGLRTTCASKMLANFDPIYDATVVQKLKAADTITIGKLNMDEFAMGSSNENSGFYATKNPWNLDYVPGGSSGGSAAAVAAGEVLFSLGSDTGGSIRQPAAYCGVVGLKPTYGRVSRYGLVAFASSLDQIGPITRTVEDNAYLLQAISGLDRMDATSANVEVGNYLAGLTGDVKGLRIAVPKEYLGEGVGEEARESVLAALKVLEGMGATWEEVSLPHSKYALATYYLLSSSEASANLSRFDGVRYGVRSDNVNNLMDLYKNTRSEGFGDEVKRRIMLGTFALSSGYYDAYYKKAQQVRTLIKNDFENVFANYDVIIGPTTPTPAFKVGEKVDDPMTMYANDILTIPVNLAGVPAISVPCGFGANNMPLGLQIIGKHFDEATIYRVAHAFEQATDHHTKKASL", "output": "Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)."}]}
+{"id": "function_valid_4498", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MALTAEQKKEILGTYGLHDTDTGSPEAQVALLTKRIADLTEHLKVHKHDHHSRRGLLLLVGRRRRLLKYVAQIDVERYRSLVERLGLRR", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.; "}]}
+{"id": "function_valid_4499", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSRYTGPSWKRSRRLGISLSGTGKEISRRNYAPGDHGPNNRAKVSEYGQQLKEKQKLRWMFGLNERQFQNLFIRAGKIREGKHGVNFMALLERRLDNIVYRLGLASTREQARQLVNHGHILVDGKRVDIPSYEVKVGQEISLRDKSKNLQQVKDALDAVVSRPPFVSFDDSKMTGTLVRLPERDEMEPEVDEALIVEWYNKKL", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; "}]}
+{"id": "function_valid_4500", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRVTFPDAKALKKIVPIVADLISEGQFVATEEGIKLVAMDPASIAMVIWEMKPEAFIDYTIEGDKEIITVSMDDLKTIVKKLKQREMVVWETDREKNKLKILARGTIKKTFSIPLLEGEETETPIPSLEYNNVVELDSKAIKEIIDDASAIADSLKFKAEPPSKLIIKAEGEMKEMTVELTEGEDAVVSIDIQEEAYASYSIDYLKKFAKAADVSDIAILKLKTDYPLWLEYRYLDKMTLIFILAPRSD", "output": "Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication."}]}
+{"id": "function_valid_4501", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSQEILNVEGMSCGHCKSAVESALNNIDGVTSADVNLENGQVSVQYDDSKVAVSQMKDAIEDQGYDVV", "output": "Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA) (By similarity)."}]}
+{"id": "function_valid_4502", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MINTETFDTHTPMMQQYLRLKAQHPDILLFYRMGDFYELFYDDAKKAAKLLDISLTKRGQSAGNPIPMAGVPHHAVENYLAKLVQLGESVAICEQIGDPATSKGPVERKVVRIVTPGTVTDEALLQERQDNLLAAIWHDNQGFGYATLDVTSGRFQISEMIELETIAAELQRSRPVELLYPESFEHMALIENFHGLRRRPLWEFELDTAKQQLNLQFGTRDLVGFGVDKATLALRAAGCLLQYVKDTQRTALPHIRGITMERQQDTVIMDAATRRNLELTQNLSGSTDNTLASVLDLCVTPMGSRMLKRWLHAPVRDRQILENRQQAIATLQEIGLELQPFLLQIGDLERVLARLALRSARPRDLARMRHAFQQLPDIHQVMDSSDSPYIKQLQKNIGRFDELQELLEKAIVETPPVLIRDGGVIAPGYNSELDEWRTLADGASNYLEQLEIREREKLGLDTLKVGFNGVHGYYIQVSRGQSHLVPIHYVRRQTLKNAERYIIPELKEYEDKVLTSKGKSLAIEKALYEELFDLLLPHLAELQTSAEALAELDVLANLAERAETLNYICPTLSDKPGIQITGGRHPVVEQVLREPFISNPLSLSSQRRLLIITGPNMGGKSTYMRQAALITLLAYIGSFVPAEKAVIGPVDRIFTRVGASDDLASGRSTFMVEMTETANILHNATEQSLVLMDEIGRGTSTYDGLSLAWACAENLANRIKAMTLFATHYFELTTLPEKLEGVVNIHLDAVEHGDTIAFMHSVQEGAASKSYGLAVASLAGVPREVIKRARQKLKELESLSNHATASHVDTPQLALLTEETSPAVEALENLNPDSLTPRQALEWIYRLKDMV", "output": "This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity."}]}
+{"id": "function_valid_4503", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKDPQSPNESFDIIVIGGGHAGCEAAITTAKLGFSTALFTINLDRIAWQPCNPAVGGPAKSQLVHEIDALGGIIGQLADETAIQKRILNASRGPAVWALRAQTDKREYSKRMIEILQNTDNLSLKEAMITELVIKEAETFSNNLKNKTKKIKGVKTFFGTYYYAKSIIITAGTFLEGRIWIGNKSMSAGRSGEQAAQGLTQSLHNLGIKTERLKTGTPARVDKKSISFDELDIQPSTASDKYFSFDPKIKNNMPQVSCHITRTTLKTHELIRNNLHLTPIYGGFIDSKGPRYCPSIEDKIVKFADKNSHQIFLEPEGINTPEIYVQGFSTGLPENIQLDLLRTLPGLNKCKMLRPAYAVEYEYIPATQLKSSLETIEIENLFSAGQINGTTGYEEAAAQGLVAGINATRKLNMKDPIIFSRESSYIGTMINDLITRDLKEPYRVLTSRSEYRLTLRGDNADRRLTPLGFEIGLIDERRWLAHKKKMKSLKEENSRLENTRLKCTDEIAKKIELDSGSKIKGSTTLKELLKRPNLHYSDFIRYDLVDKTLPISVIEGVEIDIKYEGYLKRQKNNIDQINRQSLKSLSSEINYDQIDTLSLEARENLNKIKPTNFGDASKIPGVSKADLTALLVWLKIKELKNEKKTSFAEKKLSS", "output": "NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34."}]}
+{"id": "function_valid_4504", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSTGPSEVIRIRMEAYDHAVLDQSARDIVDTVKATASIVHGPIPLPTRIERYTVLSSPFVNKKARQQYEIRTHKRLVDIVQASAKTIEALNKLSLPAGVDIKIKASAR", "output": "Involved in the binding of tRNA to the ribosomes."}]}
+{"id": "function_valid_4505", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MEQIVSSLWSDCLNHLQTKVSPIDYSTWLRPLQASFANEELTLYAQNPFVENWVKDKFLTEIIDLARFLSKNEQLKITIRVGNKPTEQNLSASSTNKEELTQDTVHKFKTGLNGRLTFDNFVQGKSNQLAKAVAQQVADNPGESHCNPFSLYGGTGLGKTHLLHAVGNEILKRNPQARVVYIHSERFVQDMVKALKNNTIENFKKFYRSLDVLMIDDIQFFAKKEASQEEFFHTFNSLFERNKQIILASDHFPKNIENIEERIKSRLNWGVSTAIEPPELETRVAILMKKAEERNVELPEEVAFYLGQKLRTNVRELEGAINRVSAWCNFTKRQITIDAVRETLKDLIASYDHLVTIENIQKIVAEYYNIKMADLKSKSRTRSIARPRQMAMALAKELTSHSLPEIGREFGGRDHTTVMHACKTINELRDTDNSIQEDYTNLTRKLSS", "output": "Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids."}]}
+{"id": "function_valid_4506", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MSKDDVIQMQGEVLENLPNATFRVKLENGHVVLGHISGKMRMHYIRILPGDKVTVELTPYDLTRARIVFRSK", "output": "One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex."}]}
+{"id": "function_valid_4507", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTARGNLFIVSAPSGAGKSSLISALLQDKPADKQVSVSHTTRQPRPGEVNGQHYHFVTKEEFKALITENAFFEWAEVFGNYYGTSRKVIEQTLTDGIDVFLDIDWQGAQQVKKVMPEAIGIFILPPSRTELEKRLTGRGQDSKEVIASRMAQAASEISHYNEYDFIIINDDFDTALADLVAIIRSQRLTDTGQIHAHNDMIQGLLAD", "output": "Essential for recycling GMP and indirectly, cGMP."}]}
+{"id": "function_valid_4508", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKVTKADIVISAVKPEQYPDSDLPEIALAGRSNVGKSSFINKILNRKKLVRISSKPGKTQTLNFFLINEMMHFVDVPGYGYAKVSKSERAAWGKMIETYFTTREQLDAAVLVVDLRHQPTSDDVMMYDFLKHYEIPTIIIATKADKIPKGKWQKHLKVVKETLAVEIGDEIVLFSSETGLGKEEAWKAIHKFTKTKNA", "output": "Necessary for normal cell division and for the maintenance of normal septation."}]}
+{"id": "function_valid_4509", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEKQYLTVTALTRYIKTKIEYDPHLQSVWLKGEISNFKNHSRGHMYFTLKDENARIAAVMFAGHNRNIKFKPENGMKVLVKGKISVYEASGSYQIYIQDMQPDGVGNLHLAYEQLKVRLEEEGLFSQVYKKAIPPYAKTIGVITSPTGAAIRDIITTIKRRYPIGNVIVFPVLVQGESAAPSIVQAIRTANEMGEIDVLIVGRGGGSIEELWAFNEEMVARAIFKSEIPIISAVGHETDFTIADFVADLRAPTPTAAAELAAPNIIELQEKVLQRTLRLQRAMRELVHKKEEKLQVLQKSYAFRYPRQVYEQKEEQLDRALEQLVLAKERYIDKKVNQLKQLSFYLEKHHPSQKIMQTKVAVETLQKQLQREMQTLLQTKEFAFVRAAQKLEALSPLKVMMRGYGLVYDEEKQVLKSVKDVSLGDAVSVQLQDGILDCSVSGIEERELNNGK", "output": "Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides."}]}
+{"id": "function_valid_4510", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MSERNQRKVYTGRVVSDKMDKTITVLVETYKTHSLYGKRVKYSKKYKAHDEQNQAKLGDIVKIMETRPLSATKRFRLVEIVEEAVII", "output": "One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA."}]}
+{"id": "function_valid_4511", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTAAHADLQAEFLEMPEGLRIDRPDVADGSALWRIAKDSKTLDLNSSYSYLLWCRDFAGTTAVARAADGTPVGFITAYVRPERPHTLLVWQVAVDAAYRGRGLAARMLDGLTARVTDEYGVTGIETTISPGNTASERLFTSYAQRHGADLEREVLFEAGLFPDAPHDPEVLYRIGPLSH", "output": "Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A."}]}
+{"id": "function_valid_4512", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MGASLNEIKQRIASTKKTSQITKAMQMVSAAKLTKSEGASKSFQEYSSKIRSVVTHLVAAQLSELRETEQSSLSEGNYHVMLAQRPVKKTGYIVITSDKGLVGGYNSSILKQTMSMIQEDHDSNKEYALIAIGGTGADFFKARGIDVSYELRGLTDQPTFEEVRKIVTTATTMYQNEVFDELYVCYNHHVNSLTSQFRVEKMLPITDLDPSEATSYEQEYLLEPSPEAILDQLLPQYAESLIYGAIIDAKTAEHAAGMTAMKTATDNAQNIISDLTISYNRARQGAITQEITEIVAGAAALE", "output": "Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex."}]}
+{"id": "function_valid_4513", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MATHSTNEFRGGLKVMVDGDPCSIIDNEFVKPGKGQAFNRVKFRNLKTGRVLERTFKSGETLPAADVVEVEMQYLYNDGEFWHFMTSENYEQHAASKEAVAEAKQWLKEEALCMVTMWNGVPLSVEPPNFVELKITETEPGVRGDTATGGTKRAKLETGAVVRVPLFLNEGEIIKVDTRRGEYVSRAK", "output": "Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation."}]}
+{"id": "function_valid_4514", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MELQTKSPTTQNDFSQHTPMMRQYLRIKAEYPDLLVFYRMGDFYELFYDDAKKAAKLLNITLTARGQSAGHAIPMAGVPYHAVENYLTKLVRLGESVVICEQIGDPATSKGPVAREVTRIITPGTVSDEALLDEHRDNTLMVIHQEKDRFGIATLDITSGRFLIQEIISENALFAEIERIRPAELLISEENSVHPLKADSIKRRPPWEFDHATALTLLCQQFQTKSLDGFGITHLPLAITAAGCLLQYVNYTQKSALPHIHSIQAEQNEEALFIDANTRRNLELITNLQGEEVHSLAWLLDHTATPMGSRLLRRWINRPLRDQILLQQRQNAVSTLLEKRNYSEIYENLRHIGDLERIVARIALRSARPRDLMQLRQALGVLPTLHQQLTNLPLNKQLQEIKNNLGLFDELFRLLKKAIIENPPIVIRDGGVIADGYDAPLDELRNMSTNSHQFLIDLEQQERERTKINTVKVGYNRIHGYYIEISRAQAKQAPTEYIRRQTLKNVERYITPELKIFEDKVLSSRSRALAREKELYEQLLDTLIEKLIPLQQCASAIANLDVLNTLAERADTLNFNAPQFCDYPIIKIEAGRHPIVENVMTDPFMPNDTHLDEKRRMLIITGPNMGGKSTYMRQTALITLLAYIGSFVPAKNAQLGPIDRIFTRIGAADDLASGRSTFMVEMTETAAILHNATEESLVLMDEVGRGTSTFDGLSLAYACASYLATKLKAFALFATHYFELTALASTLQAVKNVHLDAVEHEEKIIFLHALREGPANKSYGLQVAQLAGIPRSVIQHARQKLEELENPVISETQQPQQNELFLPIENPVLTQLDKLNPDNLTPKQALDILYQLIQLRQQK", "output": "This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity."}]}
+{"id": "function_valid_4515", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MGKLQDGIAIKRINDAITTFKNYKLDELEQGGSMAINTLSNVRAHVGLAWPAILRNCLIHTSSHLGFMKFMIDIATTWKVGAFTLLGSVGDEDPFTDVDLIYTKTCLHLGLKDNDFLQFPEEFAYEANSFLEAQSMNARVDMLTGVHNIEDKYVFRMQSISKFLKAYYTASEDVAYLTGFIKPDDSKDSILSAELLKAQVTSEVLRVRNLITTKIQKYINLYEDSQLPHFRQAALSYTQDWDVDGGVPAALPQPDITDDESPVTNPGPSAPPVSKGADQPEDEEMIRKKVETSKDAPPKAVPSGNVSARGIPAFLEDDMSEMDAPDGFHDYLTREHENNFDLAQLGLAPSV", "output": "Minor outer capsid protein."}]}
+{"id": "function_valid_4516", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MYLAILALPMFGSAVAGLRGRTIGVTGAHIITTGCLMTSAALSIVAFYEVGLSGSPVSIVIGSWIDSEFMLVQWGFLFDSLTVSMLLPVLIVSSLVHLYSISYMAGDPHNQRFFSYLSMFTFFMLVLVAGDNYFIMFVGWEGIGISSYLLINFWYTRMQANKAGMKALTVNRVGDMFLSVGFFAIFWVFGNVDYASVFSVAPYINETAITIIGLLLLVGAMAKSANIPLHTWLPDAMEGPTPVSALIHAATLVTAGVYLMLRSSPIIEYGPTVLVVITWVGALTAFFAATTGLLQNDLKRVIAYSTCSQMGYLFMAVGLSQYNVALFHLVNHAFFKALLFLAAGAVIHGMADQQDLRRLGGLVNFLPFTYTAILIGSLSLMALPFMTGFYSKDLILEVALGQYEVSGTIAYWLGTISAVFTAFYSFRLVSLTFFTTPNAPKGDYLHAHEAPMIIVIPLVILSIMSIVFGYIAKDMFVGVGTDFLSTALFQHPDHITLIEAEFGLPLLMKLLPAIGSLFGAGLALYLYHVVPSITISLTNGPIGYGVYSFLNAKWYWDALYNGLIIESGLRIGLVISKVIDRGIIELTGPYGLSTVLTGAGRSVATYDTGVITSYALYIMLGLVSLIFLVFAPTNMVFNEYGLSLILVYLSALVLLPSSTRTS", "output": "Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity)."}]}
+{"id": "function_valid_4517", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLYHENFDVIVVGGGHAGTEAALASARTGQKTLLLTHNIDTLGQMSCNPAIGGIGKGHLVKEVDAMGGLMAEAIDHAGIQFRTLNASKGPAVRATRAQADRALYKAYVRNALENAPNLTLFQQSVDDLIVEQDRVVGVVTQMGLKFHAKAVVLTVGTFLGGKIHIGMESSSGGRAGDPPSIALADRLRELPFRVDRLKTGTPPRIDARTVDFSVLEAQHGDNPTPVFSFMGKREHHPRQIPCFITHTNEQTHEVIRNNLDRSPMYAGVIEGIGPRYCPSIEDKVMRFADKNSHQIFIEPEGLTTHELYPNGISTSLPFDVQVQIVRSMKGFENAHIVRPGYAIEYDFFDPRDLKQTYETKFISGLFFAGQINGTTGYEEAAAQGLMAGLNASLYSQGKEGWSPRRDQAYMGVLIDDLSTMGTKEPYRMFTSRAEYRLLLREDNADLRLTEKARELGLIDDVRWARFNEKIENMETERQRLKSTWVNPNSAGIDELNKLLKTPMAREASGEDLLRRPEISYSQLTQLDAFAPALEDQQAAEQVEIQVKYDGYIKRQQEEIEKSLRHEHTKLPADLDYKDVKGLSNEVVAKLSEAKPESIGIASRISGITPAAISILLVHLKKHGLLKKGEEE", "output": "NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34."}]}
+{"id": "function_valid_4518", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAIKLEDKKAIVAEVNEAAKAGLSAVVADARGVTVGAMTGLRKEAREAGVYVRVVRNTLLKRAVADTEFSVLNDVFTGPTLIAFSNEHPGAAARLFKEFAKGQDKFEIKAAAFEGKFLAANQIDVLATLPTRNEAISQLMSVIQGATSKLARTLAAVRDQKEAAAA", "output": "Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors."}]}
+{"id": "function_valid_4519", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MTSPCKHGDRPPGRHDLVFVSPAGWRAMLDARDDLAADSLLARWPKMRWPTIRRRALPHEATGVALGLPLPPSAGKKRVALLVEIDHVASVARPPSLQQARAYAPRNWWPTLDRLDGLALRHSVDARVYGSLAWQSLTGLDYVTGRSDLDVLFEFRSETDIDRFVADVAAIETSAPMRLDGELMSADGAAVNWREVHGGASELLVKSIERVVLLDRHQFISGATGS", "output": "Transfers 2'-(5-triphosphoribosyl)-3'-dephosphocoenzyme-A to the apo-[acyl-carrier-protein] of the malonate decarboxylase to yield holo-[acyl-carrier-protein]."}]}
+{"id": "function_valid_4520", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTEFDLSTREGRWKHFGSVDPVKGTKPTTKNEMTDLQSTHKNFLFEIEEVGIKNLTYPVLIDQYQTAGLFSFSTSLNKNEKGINMSRILESVEKHYDNGIELEFNTLHQLLRTLQDKMNQNAAGVDVSGKWFFDRYSPVTNIKAVGHADVTYGLAIENHTVTRKELTIQAKVTTLCPCSKEISEYSAHNQRGIVTVKAYLDKNNDVIDDYKDKILDAMEANASSILYPILKRPDEKRVTERAYENPRFVEDLIRLIAADLVEFDWIEGFDIECRNEESIHQHDAFARLKYRK", "output": "Converts GTP to 7,8-dihydroneopterin triphosphate."}]}
+{"id": "function_valid_4521", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTTRIDTKFAELKAEGRPALVTYFMGGDPDLETALKVMKALPKAGADVIELGMPFSDPMADGPAIQAAGLRALNAGQTLAKTLYMAAEFRKEDDTTPIVMMGYYNPIYVYGVERFLTDAKASGVDGLIVVDLPSEMDAELCIPAMKAGINFIRLTTPTTDDKRLPKVLHNSSGFVYYVSMNGITGAAIADTAKVGEAVRHIKKSTDLPICVGFGVKTPEQAAAIATHADGVVVGTAIVNAIAGELDEKGKVKGDPVAAATRLVHALAESVRATRLEAAQ", "output": "The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate."}]}
+{"id": "function_valid_4522", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRVIVADCSAEYSGRLNASLPLAKRVLLIKADSSLLIFSELGSYKPLNWMTAPCTIREIDPAAKSAQHSRESVAGGAVDGDSATHSPESVAAGEPEKVLRVSADKGSDILEVTLQHIYSDQTYDLGEDPGLIKDGVEDHLQRYLAEQIERIGKGAKLVRREYPTAIGPVDIMAVNAEGEHVAVEIKRHGGIDGVEQLTRYCELLNRDPLLAPVHGIFAAQTITPQAQVLAKDRGFTCLILDYDDMKGTEDDSLRLF", "output": "Cleaves both 3' and 5' ssDNA extremities of branched DNA structures."}]}
+{"id": "function_valid_4523", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MTCDDFRAEDEQPIEVDERRRRLKRKANDDDDDDETVRERVDDAESSMEVFEAEYPPILDPLQDQREAKYFRERMQRFDLYSRTTGLSVDDIDWPLIRGRSLQKGRVAGISFVYDDTRYPINRFSDTWLLCVTKQKLFSFGAGCVEDLNITSFVLRRTMKVLSTYCNWLFEAAKRNNRRHITHKEIQELINRDGFRFHQYLQKFLIGRGMEYTEYNNRFFKYLHEEYNKNPGGLETIYSNQDFIAKETAQANYIYDTVRAKYGGFEELPLFRHALKISFTQPGEHYFSRFYAKRFHEALGCPPLDSEIIMILDWFGVLIMNQIAYKTIRWHEEEYNDGSFPVLDSYHKALADESKCPKACLISISLFPDDPLFDLDIDYGTNPPPVNTAYQKVRRTPRDPTPFYRLMEFEDYKSCLVKMHFNFSELTGEWLRKICARGR", "output": "Required for male development. In XO (male) animals, fem-3 directs male differentiation in all tissues. In XX (hermaphrodite) animals, it specifies the first 80 or so germ cells to be sperm. Negatively regulates male development when bound to tra-2. Together with fem-2 associates with the CBC(fem-1) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of tra-1 (By similarity)."}]}
+{"id": "function_valid_4524", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MFVVSEMADFIKAGGLGDVAAALPRALRHRYDVRVLIPGYRAVLARAGKVEIVGRVLAHAALPACDIGRIVQSDGLPIYILLSKELFERDGSPYVSTSGSEFEDNAIRFATLSHAAAQIAAGRAGLGWRPRLLHLNDWPCALAAAYVRWSGGTTPCLLTIHNLAYQGLVPYSMAAALGIPAERVSELEFYGQMSFLRGGIVHADHVNTVSVSYAQQITGPAQGCGLDRLLAGRAAKGALSGIVNGIDASWDPRTDEYLDSHFSVNHWQGRQANAAQVRKAFGLRESTGPLFAVVSRLVHQKGLDLICEVAPQIVAAGGQIAVIGGGEPEIEQQVAELTRRYPGQVGAFIGFEEGLARRMFAGADFLLMPSRFEPCGLSQMYAQRFGCLPIAHATGGLIDTVDDGVTGFLFQQASAEALRRCLERAFRTFRLPSLLSAMRRAAMLRPSGWDVAGKKYISLYERTAATAPAVATVS", "output": "Synthesizes alpha-1,4-glucan chains using ADP-glucose."}]}
+{"id": "function_valid_4525", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKRYIALDIGDVRIGVARSDIMGIIASPLETINRKKVKSVKRIAEICKENDTNLVVVGIPKSLDGEEKRQAEKVREYIEKLKKEIENLEIIEVDERFSTVIADNILKELNKNGAIEKRKVVDKVAASIILQTYLDMKK", "output": "Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA."}]}
+{"id": "function_valid_4526", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MRFMQRSKDSLAKWLSAILPVVIVGLVGLFAVTVIRDYGRETAAARQTLLEKGSVLIRALESGSRVGMGMRMHHAQQQALLEEMAGQPGVRWFAVTDEQGTIVMHSNSGMVGKQLYSPQEMQQLHPGDEEVWRRIDSADGEPVLEIYRQFQPMFAAGMHRMRHMQQYAATPQAIFIAFDASNIVSAEDREQRNTLIILFALATVLLASVLSFFWYRRYLRSRQLLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSELLELVKPTHLALQAVDLNTLINHSLQLVSQDANCREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPVNITRKDPQG", "output": "Member of the two-component regulatory system ZraS/ZraR. May function as a membrane-associated protein kinase that phosphorylates ZraR in response to high concentrations of zinc or lead in the medium (By similarity)."}]}
+{"id": "function_valid_4527", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MKRIAFVFSTAPHGSASGREGLDALLATSALTEALGVFFISDGVFQLLPGQKPDAVLARDYIATFKLFDLYDIDQCWICAASLRERGLENINFVVDATPLEPVALRRELGNYDVILRF", "output": "Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions."}]}
+{"id": "function_valid_4528", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MARYTGPSWKVSRRLGISLSGTGKELERRPYAPGQHGPTQRKKISEYGLQQAEKQKLRHMYGLTERQFKNTFNKAGKLQGKHGENFMILLEQRLDNIVYRLGLARTRRAARQLVNHGHITVDGKRVDIPSYQVSVGQVISVREKSAKNSAIAESLEVSSFVPEYVTFDAETLTGSLNRLPERSELAAEINEAFIVEFYSR", "output": "One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.; "}]}
+{"id": "function_valid_4529", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MANHSSAKKAARQTVKRTLINKKRSSAIKTFIKKVVHEISIGNKENANIALSVAQSKIMQGVKKNIIKLNTASRKISRLSRQIKSLKVNNTL", "output": "Binds directly to 16S ribosomal RNA."}]}
+{"id": "function_valid_4530", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTRAKSGKISKNRHKKILKLAKGYRGRANSCFRVAIEKVEKALQYAYRDRRNRKRDFRGLWIQRINAAVREHGLVYSQFMGALKKTEIDIDRKVLAELAVNNSDGFVSIVEKAKAHI", "output": "Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit."}]}
+{"id": "function_valid_4531", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIKSELVQIVAARNPHLYHRDVENIVNAVLDEITDALAAGNRVELRGFGAFSVKNRPSRSGRNPRTGDSVFVEEKWVPFFKTGKELRERLNPGMNDNNNGEDD", "output": "This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control."}]}
+{"id": "function_valid_4532", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MEELRGYLELDRSWQRDFLYTLILQEYIYSLAHDHGFNRTIFLENAGYEKKYSFLIVKRLITRMYQQNHLILSANDSNQNEFWGQKKNLYYQVISEGFAFIVEIPFSLQLLFSLEGKEIVKSRNLRSIHSIFPFLEDKFSHLNYVLDILIPHPVHLEILVQTIRYWTKDASSLHLLRFFLYEYRNWNSRISIKQYISFFSNRNQRLFLFLYNSHVCEYESIFIFLRNQPSHLRSTFSGAFLERIHFYEKMEHLVKVFTKNFQVILWFFKDTFMHYVRYQGKSFVASKGTSLLMIKWKYYLVNFWQCYFSVWSQPRRIYINQLSNHSLDFMGFLSSVRLNPSVVRIQMFEKSFIIDNAINTFDTLVPNIPMIGSFAKEKFCNIFGHPISKPVWADLSDSDIIDRFGRICRSLSHYYSGSSRKKSLYRIKYILRISCARTLARKHKSTVRTFLKRLGSEFLEEFFMEEEKVLSLILPRDSYTSQRFYRGRIWYLDIFCIHDLANHE", "output": "Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns."}]}
+{"id": "function_valid_4533", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MDGKNCSSVNEFLLVGISNKPGVKVTLFITFLIVYLIILVANLGMIILIRMDSQLHTPMYFFLSHLSFSDARYSTAVGPRMLVGFIAKNKSIPFYSCAMQWLVFCTFVDSECLLLAVMAFDRYKAISHPLLYTVSMSSRVCSLLMAGVYLVGIMDASVNTILTFRLCFCESNVINHFFCDVPPLLLLSCSDTQVNELVIFTIFGFIELITLSGLFVSYCYIILAVRKINSAEGRFKAFSTCTSHLTAVAIFQGTMLFMYFRPSSSYSLDQDKIISLFYSLVIPMLNPLIYSLRNKDVKEALKKLKNKKWFH", "output": "Putative odorant or sperm cell receptor."}]}
+{"id": "function_valid_4534", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MSDTTGRIPLCLIGTVAGIAVIGLVGVFFYGSYSGLGSSL", "output": "One of the components of the core complex of photosystem II (PSII). PSII is a light-driven water:plastoquinone oxidoreductase that uses light energy to abstract electrons from H(2)O, generating O(2) and a proton gradient subsequently used for ATP formation. It consists of a core antenna complex that captures photons, and an electron transfer chain that converts photonic excitation into a charge separation."}]}
+{"id": "function_valid_4535", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MNQISINNVDYIYSDGFEALHDINMSIKKGERVAILGPNGAGKSTLFNMLNGIISPTSGEVKINGLDTKVKKNLNVIRRDVGMVFQDSDDQLFNSSVMQEIAYGLVNMKVSEEELQSRVKWALNVVNMDGFEKKSPHNLSGGQKKRIALASVLAMKPEVLVLDEPTVSLDPRGTIKLVKLLKKINEEMKITIVFSTHDMDIVPLFADKVYVLNEGKLILQGGVKEVFNNKKVLRNINLRLPRVAHLAEILKSDGCIEFDELPLTIGEIRKCIKNLKGGI", "output": "Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system (By similarity)."}]}
+{"id": "function_valid_4536", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEEFQRYLELDRSQQHYFLYPLIFQEYIYALAHDHGLNINRSILLENAGYDNKFSLLIVKRLIARMYQQNHLILSTNDSNQNRFLRRNKNLYSQMISEGFAVIVEIPFYLQLKSSLESKGIVKSHNLRSIHSIFPFLEDKISHLIYGLEILIPYPVHLEILVQTLRYWVKDASSLHLLRFFLHEYCNWNTPNKAGSSFSKRNQRLFFLLYNSHLCEYESIFIFLRNQSSHLRSTSSGTLLERIYFYGKIKYLVKVFVKAFQVNLLLLKDPFMHYVRYQGKSILASKGTPFLMKKWTYYFVNLWQCHFYLWSQPGRICINQLYNHSLDILGYLSSARLNPSMVRGQMLENSFLIDNAINKFDAIVPIIPLIGSLAKAKFCNVLGHPISKAVWTDLSDSDIIDQFGRICRNLSHYHSGSSQKKSLYRIKYILRLSCARTLARKHKSTVRAFLKRLGSGLLEEFFTAEEQVLYLTFPRASSASQRLYRRRIWYLDIICINDLANHE", "output": "Usually encoded in the trnK tRNA gene intron. Probably assists in splicing its own and other chloroplast group II introns."}]}
+{"id": "function_valid_4537", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MEKTFPMTQEGLDKLKLELENLKLVKRPEVIDRIKVARSYGDLSENSEYEAAKDEQAFIEGRISTVETMIRYAEIVDNAKIAKDEVALGKNVTFVEVGETDEESYQIVGTAEADPFSGKISNESPIARVLIGKKVGDIVNVPLPVGEMTVKIVKVD", "output": "Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides."}]}
+{"id": "function_valid_4538", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MFARILGLDVGTKTVGVSVSDLLGMTAQPVETIKIDSEAGELGFERLGVLIKEYKPEKVVLGLPKHMNGDEGIRAEASRDYGTKLANEFGLEVAYQDERLTTAQAEKVLIDGGVRRKERKKSIDKLAAVLILQNYLDAHALKL", "output": "Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA."}]}
+{"id": "function_valid_4539", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MDPCECSKTGTCNCGGSCTCTNCSCTTCKKSCCSCCPSGCTKCASGCVCKGKTCDTSCCQ", "output": "Metallothioneins have a high content of cysteine residues that bind various heavy metals."}]}
+{"id": "function_valid_4540", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MIQISDRAKAHFLRLIQREGVPGMGVRLSAVDPGTARADARLEFAEPSELVGDEWLIDCGDFTLYVASASVAWLDSAEIDYVTQATGSQQLIIKAPKIKGQELSQVASLVERVCWVVENEINPQLASHGGRVEVQEVSAEGVVLLRFGGGCHGCGMVDVTLKQGVEKTLMERVHGVIAVRDATDHSTGAAPYISRNFAS", "output": "Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins."}]}
+{"id": "function_valid_4541", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MPSPCNCIETQVCICGTGCSGEGCRCGDACKCSSGCGCSGCKVVCKCQPGECACGKQCTGPDTCKCDSSCSCK", "output": "The metallothioneins are involved in the cellular sequestration of toxic metal ions."}]}
+{"id": "function_valid_4542", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTIKAPALNLPGLGADPLTQRIKEKEKKWKYKVAVLSGKGGVGKSTVAVNLTAALAKMGYFVGILDADIHGPNVAKMLGVEKEEIYAEKFDDGHFEMIPPMADFMGQVTPIKVMSMGMMVPEDQPIIWRGALVTKAIKQLLGDVKWGSLDFMIIDFPPGTGDEILTVVQSIQLDAAIIVTTPQEVALLDTGKAVNMMKKMEVPYIAVVENMSYLICPHCGNKIDIFGEGGGEKLAEKEGVDFLGKIPIDLKAREASDLGIPIVLYGDTPAAKAFMEIAEKLVNKLKEMKGDEKKE", "output": "Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP."}]}
+{"id": "function_valid_4543", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MNTYKNSLNHFLNLVDCLEKIPNVGKKSAFKMAYHLGLENPYLALKITHALRNALENLKTCASCNALSETEVSEICSDESRQNSQLCMVLHPRDVFILEDLKDFLGRYYVLNSIEDVDFNALEKRLIGENIKEIIFAFPPTLANDSLMLYIEDKLQHLHLTFTKIAQGVPTGVNFENIDSVSLSRAFNSRIKA", "output": "May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO."}]}
+{"id": "function_valid_4544", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKPIVSILIFCALAVVIMGHPLDSGYGIPHIVEKLPNGQWCKTPGDDCSKNNECCKPKDPENYSSGCASQWSGMQGKRVNMCRICYIESSMC", "output": "Probable neurotoxin with ion channel impairing activity."}]}
+{"id": "function_valid_4545", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "NRDVAACARFIDDFCDTLTPNIYRPRDNGQRCYAVNGHRCDFTVFNTNNGGNPIRASTPNCKTVLRTAANRCPTGGRGKINPNAPFLFAIDPNDGDCSTNF", "output": "Has antiviral activity against tobacco mosaic virus and antitumor activity."}]}
+{"id": "function_valid_4546", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MTRMVNCVKMEQELEGLDFPPFPGDLGQKIYENVSKEAWKQWLAQQTILINEYRLSSLDPKAQNFLKEEMQKFLFGGEDLEMPEEFQAID", "output": "Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes."}]}
+{"id": "function_valid_4547", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MAVKILTDSTSCMNNDLINKFHINLVSLSVSFDDESFKEKDISNEVFYEKMNEKGIPKSSQPSIEDLCSVMEEVVSVGDELLCIFISSDMSGTYSTAHIARDMVIEKYKDAKIEILDSRSNCMQLGFAAISAARAAMDGKSLEEVKLAAEENMKKSRFLFIPDNLVYLKKGGRIGGAGALIGNLLKIIPILTVEDGKTSVFAKIRTKKRAVETMVQRVLEDTDKFGMGGIAVHHINCYDEAKRLAETIKNKFKVDPIICDIGPVIGLHVGPGAIGIAYYTEKNMR", "output": "May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism."}]}
+{"id": "function_valid_4548", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MKNTKTSQEQVIELKLSDRQKKVLKSIVDEYTISATPVSSKLLVQKEFKDQSSATIRNEMMFLEKNGLIEKQHISGGRVPSLKGYDFYNKNLINKNNNVSDNFKMRLHKILSKRYSNIDEILNAAVSIINETTQLPAVVTKTSSDELLKRIDLVKINDNSALVLIVTSSENILTHSIKLDKNTKFNDLQTCFSVLDERLVDTKLSLISSKLDLIVDIVRNKLEEVEYYFSKIVHRVFDFYAYKPNIDSKTYGVKYLTKHSEFEDQQKLNDLLNLLEDSTIWQQIALNKKTDGLAKIMLGNEIGHEHLAIATTQINLANTNHQITVVGPTRMDYAKIKALLDFLKIEIEKILGSTNEH", "output": "Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons."}]}
+{"id": "function_valid_4549", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MTRILLLLLGFYQYFISPLLGNNCRFHPTCSEYAKEAISMHGSIKGLWFTFKRIIKCQPFCNGGYDTVPISIKNSKPLNKKI", "output": "Could be involved in insertion of integral membrane proteins into the membrane."}]}
+{"id": "function_valid_4550", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MVHPQLKRSIESLSFSGYKLTRRNLYNAPALKVMGRSVNNSSSNNNDQQQYNLESAKQNTQIVVIGAGLAGLSAAQHLLRHGFRSTIVLEATDRYGGRVNSKRFGDTYCELGAKWVNMNIDGAHNTIYELLRNAEGLRKQLKQRECANYVHTQGREVPPNMVELIDMQFRQLCRGFKVSEKVKSGGDLHVLDNVMAYFKTESEKLVGHSYPDPEKRALAREIFQSLFKEFSSILGCCLEYVNIEHITSCPVQQELRPLYVPTGLDNVLDTLTQHISKEQLQTGKPVGSIQWQTLSDFGAPTSPLPQERKCVACLDGTLYSADHIICTLPLGVLKNFSAILFKPALPLEKLQAIRNLGYGNPVKIYLAYKRPISRWLKSNLRPLGAQLGKDEPAITVNGRQERLWTQQVVEISQLPSSQHVLEIRVGGGYYDEIEKLPDVTLLEQITALLRQCLRNRLVPYPQALLRSNWSTSACYLGGRPYFSTTSSARDVQRLAEPLGDIAPTLLFAGDATALKGFGTIDGARTSGIREAQRIIDYYYLKQYM", "output": "Has a non-vital function."}]}
+{"id": "function_valid_4551", "name": "Protein Function Description", "instruction": "Can you provide the functional description of the following protein sequence?", "instances": [{"input": "MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNYVIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYIIDGLLDKMLINEREAKMIHAVIDRETLSMDMVSRDIIRANILKRLLPVINYY", "output": "Negative regulator of clpC, clpB and clpP transcription by binding directly and specifically to their promoter region."}]}
+{"id": "function_valid_4552", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSRIVNCVKLKREAEGLDFPPYPGELGTRIWQQISKEAWEEWKQIQTRLVNENRLNLADARARKYLQQQMERFLFEDGTVEAQGYVPPSA", "output": "Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes."}]}
+{"id": "function_valid_4553", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MSIRILPDSEIKAAASSFHAPALLFANPKNLYQRRIARFTSLSNAHPLEDYLHFASQVAEAQLAVLQQQPIAQDPRLSAEKLSAEDLAKQPLNAQRWQRDPVWQTLLMAILAEMKPKANETILNTIETLEKYSKAERDSIADKLLAQEFEQISSAQAVFIWAALSLYWLQLVQQIPHSSHKESGESLHVCPICASAPVTSVIHFGAEQGLRYLHCALCETEWNMVRSKCTNCDQTGKLDYWSLDSEIAAVKAESCGDCHSYLKALYQERDPKVEAVADDLASIFLDVEMEEKGLQRSGLNPFLFPNPEA", "output": "Necessary for formate dehydrogenase activity."}]}
+{"id": "function_valid_4554", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MHEIITLQLGQRANYLATHFWNLQESYFTYNEEEESPVDHDVHFRPGVGADGSETYTPRTVIYDLKGGFGTLRKYNALYELTEDATPGQGLWDGREVLQQQAPIPQSDYQKSLDAGLPAPTLSAETVRYWSDYNRLFYHPRSIVQLNDYELNSKIMPFEDWTIGEELFNELDKEHDLLDRDVRPFAEECDQLRALQVFTGSDDAWGGFAAKYIDRIRDEYGKKSVWVWAIENGKKVDRQTQFKRDLNKARSVHAISTQASLYAPIIDPPSRIPQSIYLDARSEWYTSALVSAAMESVSLPTRLRPYHDFEASLAGDDGTHKIFELQSTMVQDGEDAANSPIKTEFDLDFTYDGLACKNSHHVFNQLQVSRGLADGGGESGGEDQGILRRKRHFNSEPMFQRFHTTLPFPILDSFPQNMFPELKSKEKINILAALTVSSRTAERLKVYETLAGRVAGVDERETLVNGLGEIRETYETGWMSDSDFDDD", "output": "Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance."}]}
+{"id": "function_valid_4555", "name": "Protein Function Description", "instruction": "Predict the general functional description of the protein sequence.", "instances": [{"input": "MLSFSQNRSHSLEQSLKEGYSQMADLNLSLANEAFPIECEACDCNETYLSSNSTNE", "output": "Antitoxin component of a type II toxin-antitoxin (TA) system. Labile antitoxin that binds to cognate MazF toxin and counteracts its endoribonuclease activity."}]}
+{"id": "function_valid_4556", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKTTLDLPDELMRAIKVRAAQQGRKMKDVVTELLRSGLSQTHSGAPIPTPRRVQLPLVHCGGAATREQEMTPERVAAALLDQEAQWWSGHDDAAL", "output": "Antitoxin component of a type II toxin-antitoxin (TA) system."}]}
+{"id": "function_valid_4557", "name": "Protein Function Description", "instruction": "Generate the functional description in free-text form based on the protein sequence.", "instances": [{"input": "MARTVFCEYLKQEAEGLDFQLYPGELGKRIFDSISKQAWSEWIKKQTMLVNEKKLSMMNAEHRKLLETEMVNFLFEGKEVQIEGYVPVEQK", "output": "Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes."}]}
+{"id": "function_valid_4558", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDMAELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFDRLAENEVYEIVKAFDQEFFKLEDILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQFLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFEHIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRVADGQESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYRYLSSNHYEVH", "output": "Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons."}]}
+{"id": "function_valid_4559", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MTRMVFCQRLKKEAPGMAFQLVPGELGKRIFDNICQEAWAEWQKKQTMLINEKKLNMMNAEHRALLQTEMEKYLFEDGDVQIEGYVPPSEK", "output": "Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes."}]}
+{"id": "function_valid_4560", "name": "Protein Function Description", "instruction": "What is the functional description of the protein sequence?", "instances": [{"input": "MKKIFLAMIHFYQRFISPLTPPTCRFYPTCSEYTREAIQYHGAFKGLYLGIRRILKCHPLHKGGFDPVPLKKDKSASKHSHKHNH", "output": "Could be involved in insertion of integral membrane proteins into the membrane."}]}
+{"id": "function_valid_4561", "name": "Protein Function Description", "instruction": "Predict the functional description of the protein sequence below.", "instances": [{"input": "MKTIPSEVRCSRLCPACTNAALRLPRNAGRALIWIYRHTLSPLVGFNCRHLPTCSAYGDEAIARFGLWGGGWMTLARILRCRPWGTSGIDNVPVAKPSGATWYRPWRYGRWRGVNAK", "output": "Could be involved in insertion of integral membrane proteins into the membrane."}]}
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